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Articles 11371 - 11400 of 42552
Full-Text Articles in Entire DC Network
Role Of Tnfα Antagonists And Genetic Polymorphisms In Modulating Susceptibility To Mycobacterial Infection Among Patients With Crohn's Disease, Ahmad Qasem
Electronic Theses and Dissertations
Tumor Necrosis Factor alpha antagonists (anti-TNFα) have been extensively used for Crohn's disease (CD) treatment. Even though they may control CD symptoms initially, treatment response varies among patients, which seems to depend on single nucleotide polymorphisms (SNPs) in TNFα receptors superfamily 1A and 1B (TNFRSF1A/B). Most importantly, M. tuberculosis infection has been strongly associated with these medications, but no studies have elucidated the effects of anti-TNFα on CD associated with MAP (Mycobacterium avium subspecies paratuberculosis; a possible causative agent of CD, and closely related to M. tuberculosis). Here, we investigated the effects of recombinant inflammatory cytokines and anti-TNFα therapeutics on …
The Evaluation Of Classifier Performance On The Forensic Analysis Of Fire Debris And The Expansion Of The Substrate Database, Alyssa Allen
The Evaluation Of Classifier Performance On The Forensic Analysis Of Fire Debris And The Expansion Of The Substrate Database, Alyssa Allen
Electronic Theses and Dissertations
The current protocols in fire debris analysis rely on ignitable liquid pattern recognition and the identification of target compounds. These practices allow fire debris analysts to determine whether a sample contains or is absent of ignitable liquid residue and to classify that type of ignitable liquid based upon subjective thresholds. A statistical approach using computationally mixed datasets was devised in this research to generate an objective approach to the classification of fire debris samples and to determine error rates. Quadratic, linear, and partial least squares linear discriminant analysis (QDA, LDA, and PLS-DA) models were developed and evaluated to determine the …
An Exploration Of Florida Public School Districts' Language Development Programs For Children Before They Enter Kindergarten, Sharon Ochotorena
An Exploration Of Florida Public School Districts' Language Development Programs For Children Before They Enter Kindergarten, Sharon Ochotorena
Electronic Theses and Dissertations
The purpose of the study was to determine the extent to which preschool programs and the 10 research-based components that develop language are present in Florida public school districts. Based on qualitative methods of analysis, the study utilized two primary sources of data collection to answer the two research questions that follow: 1. Of the 67 traditional public school districts in Florida, which have language development programs for children under the age of 5, excluding those subsidized by Part B of the IDEA? 2. How do components of the programs in the sample of school districts that have language development …
Molecular Basis Of Membrane Pore Formation By Amyloid Beta Peptide, Nabin Kandel
Molecular Basis Of Membrane Pore Formation By Amyloid Beta Peptide, Nabin Kandel
Electronic Theses and Dissertations
Alzheimer's Disease (AD) is a neurodegenerative disorder that affects around 50 million people worldwide and causes cognitive decline, brain atrophy and death. Despite extensive basic and clinical studies and drug development efforts, currently no effective treatments are available for AD. The amyloid β (Aβ) peptide is neurotoxic and is tightly associated with AD pathology, but the molecular mechanism of its action remains unclear. There are various forms of Aβ in the brain, ranging from the full length Aβ1-42 to shorter peptides, such as a strongly toxic Aβ25-35 fragment. The Amyloid Cascade Hypothesis (ACH) postulated that extracellular Aβ deposits cause the …
Towards More Reliable Neural Network Learning Models, Navid Kardan
Towards More Reliable Neural Network Learning Models, Navid Kardan
Electronic Theses and Dissertations
Ideally, when a neural network makes a wrong decision or encounters an out-of-distribution example, its predictive confidence should be as low as possible. Three primary contributions in this dissertation address this challenge. The first two contributions are new approaches to mitigate overconfident predictions in modern neural networks. In the first (1), called competitive overcomplete output layer neural networks, several classifiers, as part of the same output layer, are trained simultaneously and later their consensus produces more reliable predictions. The second approach (2) reformulates the original classification problem into several new versions by combining classes together and training a classifier on …
The Impact Of Youths' Digital Citizenship Levels On Their Self-Efficacy, Madison Gannon
The Impact Of Youths' Digital Citizenship Levels On Their Self-Efficacy, Madison Gannon
Electronic Theses and Dissertations
The purpose of this study is to identify youths' levels of digital citizenship, to identify youths' levels of self-efficacy, and to determine the relationship between their digital citizenship levels and their self-efficacy levels. Their digital citizenship levels were determined based on five factors: 1) Ethics for Digital Environment, 2) Fluency for Digital Environment, 3) Reasonable/Critical Decisions, 4) Self-Identity in Digital World, and 5) Social/Cultural Engagement to Society. Their self-efficacy levels were determined based on three factors: 1) Academic Self-efficacy, 2) Social Self-efficacy, and 3) Emotional Self-efficacy. The study has four major phases. First, an in-depth literature review was conducted on …
Ribbeting Results: Emergent Infectious Diseases In Wetland Systems, Ariel Horner
Ribbeting Results: Emergent Infectious Diseases In Wetland Systems, Ariel Horner
Electronic Theses and Dissertations
North American amphibians have recently been impacted by two major emerging pathogens, the fungus Batrachochytrium dendrobatidis (Bd) and iridoviruses in the genus Ranavirus (Rv). Environmental, seasonal and host factors may play important roles in disease dynamics, but few studies incorporate these components into their analyses. Here, we investigated the role of environmental, seasonal, genetic and location effects on driving Bd and Rv infection prevalence and severity in a biodiversity hot spot, the southeastern United States. We used quantitative PCR to characterize Bd and Rv dynamics in natural populations of three amphibian species: Notophthalmus perstriatus, Hyla squirella and Pseudacris ornata and …
Informe Parcial Proyecto “Paleobotánica Y Paisaje En El Amazonas Sudoccidental: Prospección, Excavaciones Arqueológicas Y Obtención De Muestras De Suelo En Los Llanos De Mojos, Bolivia”, John H. Walker, Neil Duncan, Juan Carlos Chávez Quispe, Thomas Warren Lee, Danielle Young, Hanna Park, Mabel Ramos Fernandez, Lizeth Duran Vargas, Andrea Cruz Diez, Jaime Bocchietti Arias
Informe Parcial Proyecto “Paleobotánica Y Paisaje En El Amazonas Sudoccidental: Prospección, Excavaciones Arqueológicas Y Obtención De Muestras De Suelo En Los Llanos De Mojos, Bolivia”, John H. Walker, Neil Duncan, Juan Carlos Chávez Quispe, Thomas Warren Lee, Danielle Young, Hanna Park, Mabel Ramos Fernandez, Lizeth Duran Vargas, Andrea Cruz Diez, Jaime Bocchietti Arias
ProSIGAB Documents
No abstract provided.
Reconfigurable Reflectarray Antennas With Bandwidth Enhancement For High Gain, Beam-Steering Applications, Michael Trampler
Reconfigurable Reflectarray Antennas With Bandwidth Enhancement For High Gain, Beam-Steering Applications, Michael Trampler
Electronic Theses and Dissertations
Reconfigurable reflectarrays are a class of antennas that combine the advantages of traditional parabolic antennas and phased array antennas. Chapter 1 discusses the basic operational theory of reflectarrays and their design. A review of previous research and the current status is also presented. Furthermore the inherent advantages and disadvantages of the reflectarray topography are presented. In chapter 2, a BST-integrated reflectarray operating at Ka band is presented. Due to the monolithic integration of the tuning element, this design is then extended to V band where a novel interdigital gap configuration is utilized. Finally to overcome loss and phase limitations of …
Hybrid Multi-Objective Optimization Of Left Ventricular Assist Device Outflow Graft Anastomosis Orientation To Minimize Stroke Rate, Blake Lozinski
Hybrid Multi-Objective Optimization Of Left Ventricular Assist Device Outflow Graft Anastomosis Orientation To Minimize Stroke Rate, Blake Lozinski
Electronic Theses and Dissertations
A Left Ventricular Assist Device (LVAD) is a mechanical pump that is utilized as a bridge to transplantation for patients with a Heart Failure (HF) condition. More recently, LVADs have been also used as destination therapy and have provided an increase in the quality of life for patients with HF. However, despite improvements in VAD design and anticoagulation treatment, there remains a significant problem with VAD therapy, namely drive line infection and thromboembolic events leading to stroke. This thesis focuses on a surgical maneuver to address the second of these issues, guided by previous steady flow hemodynamic studies that have …
Theoretical And Experimental Study For Tailoring The Electromagnetic Properties Of Conductive Materials, Jeffrey Jennings
Theoretical And Experimental Study For Tailoring The Electromagnetic Properties Of Conductive Materials, Jeffrey Jennings
Electronic Theses and Dissertations
Induction in leaded, implanted medical devices exposed to radio frequency (RF) magnetic fields during magnetic resonance imaging (MRI) produce Joule heating in adjacent tissues causing various issues, including death. Given the importance of MRI as a diagnostic tool and the growth in leaded device-related treatments, identification of a solution ensuring their compatibility is of great interest. Electromagnetic (EM) surface property tailoring in lead materials to change their inductive response by adding functionally-graded, heterogeneous surface layers is a possible solution. However, non-uniform EM properties introduce two challenges: the added complexity of analyses and characterization of the graded region. This dissertation addresses …
Investigation Of Flow Field Structures In A Rectangular Channel With A Pin Fin Array, Patrick Tran
Investigation Of Flow Field Structures In A Rectangular Channel With A Pin Fin Array, Patrick Tran
Electronic Theses and Dissertations
Pin fin arrays are commonly found in heat exchangers, turbine blades, and electronic heat sinks. Fin arrays are extended surfaces that are used as turbulence promoters by inducing horseshoe vortex (HSV) and von Karman vortex (KV) structures. The horseshoe vortex are primarily studied in the leading edge of the blunt body, whereas the KV are formed in the trailing side. This study presents an experimental investigation of flow field structures and pressure loss on staggered pin fin array in the wake region, where KV are dominate. These flow structures increase the local levels turbulence and generate eddies that promote flow …
Safety, Operational, And Design Analyses Of Managed Toll And Connected Vehicles' Lanes, Moatz Saad
Safety, Operational, And Design Analyses Of Managed Toll And Connected Vehicles' Lanes, Moatz Saad
Electronic Theses and Dissertations
Managed lanes (MLs) have been implemented as a vital strategy for traffic management and traffic safety improvement. The majority of previous studies involving MLs have explored a limited scope of the impact of the MLs segments as a whole, without considering the safety and operational effects of the access design. Also, there are limited studies that investigated the effect of connected vehicles (CVs) on managed lanes. Hence, this study has two main objectives: (1) the first objective is achieved by determining the optimal managed lanes access design, including accessibility level and weaving distance for an at-grade access design. (2) the …
Design And Structural Analysis Of Morphing Wings, Nicholas Fernandez
Design And Structural Analysis Of Morphing Wings, Nicholas Fernandez
Electronic Theses and Dissertations
Many natural flyers and marine swimmers can morph their wings during a number of unsteady maneuverings. With such wing morphing they are able to control the unsteady aerodynamic forces. A number of man-made flyers, such as unmanned aerial vehicles and micro air vehicles, fly in comparable Reynolds number range, but they are yet to acquire similar morphing capabilities as natural flyers or swimmers. Moreover, the knowledge of fluid structural interaction (FSI) of such morphing wings is not well developed. Hence there is a need to investigate the FSI of morphing wings. In this thesis, a morphing wing was designed and …
Gan Power Devices: Discerning Application-Specific Challenges And Limitations In Hemts, Andrew Binder
Gan Power Devices: Discerning Application-Specific Challenges And Limitations In Hemts, Andrew Binder
Electronic Theses and Dissertations
GaN power devices are typically used in the 600 V market, for high efficiency, high power-density systems. For these devices, the lateral optimization of gate-to-drain, gate, and gate-to-source lengths, as well as gate field-plate length are critical for optimizing breakdown voltage and performance. This work presents a systematic study of lateral scaling optimization for high voltage devices to minimize figure of merit and maximize breakdown voltage. In addition, this optimization is extended for low voltage devices ( < 100 V), presenting results to optimize both lateral features and vertical features. For low voltage design, simulation work suggests that breakdown is more reliant on punch-through as the primary breakdown mechanism rather than on vertical leakage current as is the case with high-voltage devices. A fabrication process flow has been developed for fabricating Schottky-gate, and MIS-HEMT structures at UCF in the CREOL cleanroom. The fabricated devices were designed to validate the simulation work for low voltage GaN devices. The UCF fabrication process is done with a four layer mask, and consists of mesa isolation, ohmic recess etch, an optional gate insulator layer, ohmic metallization, and gate metallization. Following this work, the fabrication process was transferred to the National Nano Device Laboratories (NDL) in Hsinchu, Taiwan, to take advantage of the more advanced facilities there. Following fabrication, a study has been performed on defect induced performance degradation, leading to the observation of a new phenomenon: trap induced negative differential conductance (NDC). Typically NDC is caused by self-heating, however by implementing a substrate bias test in conjunction with pulsed I-V testing, the NDC seen in our fabricated devices has been confirmed to be from buffer traps that are a result of poor channel carrier confinement during the dc operating condition.
Training Neural Networks Through The Integration Of Evolution And Gradient Descent, Gregory Morse
Training Neural Networks Through The Integration Of Evolution And Gradient Descent, Gregory Morse
Electronic Theses and Dissertations
Neural networks have achieved widespread adoption due to both their applicability to a wide range of problems and their success relative to other machine learning algorithms. The training of neural networks is achieved through any of several paradigms, most prominently gradient-based approaches (including deep learning), but also through up-and-coming approaches like neuroevolution. However, while both of these neural network training paradigms have seen major improvements over the past decade, little work has been invested in developing algorithms that incorporate the advances from both deep learning and neuroevolution. This dissertation introduces two new algorithms that are steps towards the integration of …
Task Focused Robotic Imitation Learning, Pooya Abolghasemi
Task Focused Robotic Imitation Learning, Pooya Abolghasemi
Electronic Theses and Dissertations
For many years, successful applications of robotics were the domain of controlled environments, such as industrial assembly lines. Such environments are custom designed for the convenience of the robot and separated from human operators. In recent years, advances in artificial intelligence, in particular, deep learning and computer vision, allowed researchers to successfully demonstrate robots that operate in unstructured environments and directly interact with humans. One of the major applications of such robots is in assistive robotics. For instance, a wheelchair mounted robotic arm can help disabled users in the performance of activities of daily living (ADLs) such as feeding and …
Predictors Of Territorial Work Behavior: An Investigation Of Individual Differences In Personality Using The Hexaco Model, Andrew White
Predictors Of Territorial Work Behavior: An Investigation Of Individual Differences In Personality Using The Hexaco Model, Andrew White
Electronic Theses and Dissertations
To date, little research has examined the relationship between territorial work behavior and individual differences in personality. Using hierarchical multiple regression, dimension-level and facet-level personality traits of the HEXACO model of personality were examined to determine whether personality traits predict territorial work behaviors. Based on a sample of 160 workers from Amazon's Mechanical Turk, it was observed that the dimensions of Honesty-Humility, Emotionality, Openness to Experience, and Altruism predicted territorial work behaviors. In addition, facet-level traits from these dimensions, in addition to facets from the Extraversion and Agreeableness dimension, explained variance in each of the territorial behaviors. Furthermore, quantile regression …
Assessment Of A Surface Water Supply For Source And Treated Distribution System Quality, Angela Rodriguez
Assessment Of A Surface Water Supply For Source And Treated Distribution System Quality, Angela Rodriguez
Electronic Theses and Dissertations
This study focused on providing a source to tap assessment of surface water systems with respect to (i) the use of alternative biomonitoring tools, (ii) disinfection byproduct (DBP) formation and control, and (iii) corrosion control. In the first study component, two water systems were microbiologically evaluated using adenosine triphosphate (ATP) bioluminescence technology. It was determined that microbial ATP was useful as a surrogate for biomonitoring within a surface water system when paired with traditional methods. Although microbial activity differed between distribution systems that used either chloramine or chlorine disinfectant, in both cases flowrate and season affected microbial ATP values. In …
Analysis Of Residual Stress And Damage Mechanisms Of Thermal Barrier Coatings Deposited Via Ps-Pvd And Eb-Pvd, Linda Rossmann
Analysis Of Residual Stress And Damage Mechanisms Of Thermal Barrier Coatings Deposited Via Ps-Pvd And Eb-Pvd, Linda Rossmann
Electronic Theses and Dissertations
Thermal barrier coatings (TBCs) are critical to gas turbine engines, as they protect the components in the hot section from the extreme temperatures of operation. The current industry standard method of applying TBCs for turbine blades in jet engines is electron-beam physical vapor deposition (EB-PVD), which results in a columnar structure that is valued for its high degree of strain tolerance. An emerging deposition method is plasma-spray physical vapor deposition (PS-PVD), capable of producing a variety of customizable microstructures as well as non-line-of-sight deposition, which allows more complex geometries to be coated, or even multiple parts at once. The pseudo-columnar …
Improvement Of Data-Intensive Applications Running On Cloud Computing Clusters, Ibrahim Adel Ibrahim
Improvement Of Data-Intensive Applications Running On Cloud Computing Clusters, Ibrahim Adel Ibrahim
Electronic Theses and Dissertations
MapReduce, designed by Google, is widely used as the most popular distributed programming model in cloud environments. Hadoop, an open-source implementation of MapReduce, is a data management framework on large cluster of commodity machines to handle data-intensive applications. Many famous enterprises including Facebook, Twitter, and Adobe have been using Hadoop for their data-intensive processing needs. Task stragglers in MapReduce jobs dramatically impede job execution on massive datasets in cloud computing systems. This impedance is due to the uneven distribution of input data and computation load among cluster nodes, heterogeneous data nodes, data skew in reduce phase, resource contention situations, and …
Interactive Perception In Robotics, Masoud Baghbahari Baghdadabad
Interactive Perception In Robotics, Masoud Baghbahari Baghdadabad
Electronic Theses and Dissertations
Interactive perception is a significant and unique characteristic of embodied agents. An agent can discover plenty of knowledge through active interaction with its surrounding environment. Recently, deep learning structures introduced new possibilities to interactive perception in robotics. The advantage of deep learning is in acquiring self-organizing features from gathered data; however, it is computationally impractical to implement in real-time interaction applications. Moreover, it can be difficult to attach a physical interpretation. An alternative suggested framework in such cases is integrated perception-action. In this dissertation, we propose two integrated interactive perception-action algorithms for real-time automated grasping of novel objects using pure …
Simulation, Analysis, And Optimization Of Heterogeneous Cpu-Gpu Systems, Christopher Giles
Simulation, Analysis, And Optimization Of Heterogeneous Cpu-Gpu Systems, Christopher Giles
Electronic Theses and Dissertations
With the computing industry's recent adoption of the Heterogeneous System Architecture (HSA) standard, we have seen a rapid change in heterogeneous CPU-GPU processor designs. State-of-the-art heterogeneous CPU-GPU processors tightly integrate multicore CPUs and multi-compute unit GPUs together on a single die. This brings the MIMD processing capabilities of the CPU and the SIMD processing capabilities of the GPU together into a single cohesive package with new HSA features comprising better programmability, coherency between the CPU and GPU, shared Last Level Cache (LLC), and shared virtual memory address spaces. These advancements can potentially bring marked gains in heterogeneous processor performance and …
Multi-Modal Interfaces For Sensemaking Of Graph-Connected Datasets, Anthony Wehrer
Multi-Modal Interfaces For Sensemaking Of Graph-Connected Datasets, Anthony Wehrer
Electronic Theses and Dissertations
The visualization of hypothesized evolutionary processes is often shown through phylogenetic trees. Given evolutionary data presented in one of several widely accepted formats, software exists to render these data into a tree diagram. However, software packages commonly in use by biologists today often do not provide means to dynamically adjust and customize these diagrams for studying new hypothetical relationships, and for illustration and publication purposes. Even where these options are available, there can be a lack of intuitiveness and ease-of-use. The goal of our research is, thus, to investigate more natural and effective means of sensemaking of the data with …
Design, Development, And Testing Of A Miniature Fixture For Uniaxial Compression Of Ceramics Coupled With In-Situ Raman Spectrometer, Ryan Jordan
Electronic Theses and Dissertations
This thesis is about the design, development and integration of an in-situ compression stage which interfaces through the Leica optical microscope coupled with a Renishaw InVia micro-Raman spectrometer. This combined compression stage and Raman system will enable structural characterization of ceramics and ceramic composites. The in-situ compression stage incorporates a 440C stainless steel structural components, 6061 aluminum frame, a NEMA 23 stepper motor. Two load screws that allow to apply compressive loads up to 14,137 N, with negligible off axis loading, achieving target stresses of 500 MPa for samples of up to 6.00 mm in diameter. The system will be …
Design, Synthesis And Characterization Of Biomimetic, Bioinspired And Bio-Related Functional Polymers For Atmospheric Water Recovery, Abdullah Alqassar
Design, Synthesis And Characterization Of Biomimetic, Bioinspired And Bio-Related Functional Polymers For Atmospheric Water Recovery, Abdullah Alqassar
Electronic Theses and Dissertations
Atmospheric water recovery in changing environments has received wide attention in environmental science and engineering communities due to rapid population growth and frequent droughts. This study is focused on the design, synthesis, and characterization of biomimetic, bioinspired, and bio-related functional polymers (b3p) to help resolve the water supply issue especially in arid or semi-arid regions. It is aimed to develop unique synthetic methods to access well-defined polymers with the aid of nanomaterials and metal to produce next generation polymer materials for better atmospheric water recovery. The design of such new b3p is bioinspired by some skin materials of biological species …
Implications Of Groundwater Plume Transport And Analysis Of Karst Aquifer Characteristics In Central Florida, Daljit Sandhu
Implications Of Groundwater Plume Transport And Analysis Of Karst Aquifer Characteristics In Central Florida, Daljit Sandhu
Electronic Theses and Dissertations
Groundwater aquifers make up the primary source of drinking water in Florida. It is imperative to protect and maintain water quality to ensure optimal drinking water conditions. Florida is known for being prone to sinkholes due to karst features. One sinkhole event occurred beneath a phosphogypsum stack, and leaked a large amount of radioactive waste in the Floridan aquifer, raising water quality concerns. To study the behavior of contaminant transport, the radioactive waste plume was modeled by coupling hydraulic and chemistry concepts. Adsorption was studied to see if it can serve as a potential remediation solution to the contaminant waste, …
Rethinking Routing And Peering In The Era Of Vertical Integration Of Network Functions, Prasun Kanti Dey
Rethinking Routing And Peering In The Era Of Vertical Integration Of Network Functions, Prasun Kanti Dey
Electronic Theses and Dissertations
Content providers typically control the digital content consumption services and are getting the most revenue by implementing an "all-you-can-eat" model via subscription or hyper-targeted advertisements. Revamping the existing Internet architecture and design, a vertical integration where a content provider and access ISP will act as unibody in a sugarcane form seems to be the recent trend. As this vertical integration trend is emerging in the ISP market, it is questionable if existing routing architecture will suffice in terms of sustainable economics, peering, and scalability. It is expected that the current routing will need careful modifications and smart innovations to ensure …
Long-Term Carbon And Copper Impact On Nutrient Removal Via Green Sorption Media In Dynamic Linear Ditch Environments, Diana Ordonez
Long-Term Carbon And Copper Impact On Nutrient Removal Via Green Sorption Media In Dynamic Linear Ditch Environments, Diana Ordonez
Electronic Theses and Dissertations
Nutrient-laden stormwater runoff causes environmental and ecological impacts on receiving water bodies. Biosorption Activated Media (BAM) composed of the sand, tire crumb, and clay have been implemented in stormwater best management practices due to its ability to efficiently remove nutrients from stormwater runoff, such as in roadside linear ditches, via unique chemophysical and microbiological processes. In this study, a set of fixed-bed columns were set up to simulate some external forces in roadside linear ditches and examine how these external forces affect the performance of BAM. In our experiment, scenario 1 simulates the impact that animals such as tortoises, moles …
Blockchain-Driven Secure And Transparent Audit Logs, Ashar Ahmad
Blockchain-Driven Secure And Transparent Audit Logs, Ashar Ahmad
Electronic Theses and Dissertations
In enterprise business applications, large volumes of data are generated daily, encoding business logic and transactions. Those applications are governed by various compliance requirements, making it essential to provide audit logs to store, track, and attribute data changes. In traditional audit log systems, logs are collected and stored in a centralized medium, making them prone to various forms of attacks and manipulations, including physical access and remote vulnerability exploitation attacks, and eventually allowing for unauthorized data modification, threatening the guarantees of audit logs. Moreover, such systems, and given their centralized nature, are characterized by a single point of failure. To …