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The Effects Of Trivalent Arsenicals And Thioredoxin Reductase Inhibitors On Selenium Metabolism In Lung Cell Culture Models, Sarah Ryann Talbot Jan 2007

The Effects Of Trivalent Arsenicals And Thioredoxin Reductase Inhibitors On Selenium Metabolism In Lung Cell Culture Models, Sarah Ryann Talbot

Electronic Theses and Dissertations

Arsenic exposure, through various routes, is associated with the development of cancer of the skin, lung, liver, kidney, and bladder. Treatment of cells in culture with trivalent arsenicals has been shown to increase reactive oxygen species (ROS). In particular, monomethylarsonous acid (MMAIII), a trivalent metabolite of arsenite, is highly cytotoxic and possibly carcinogenic. Three trivalent arsenicals; arsenite, arsenic trioxide (ATO), and MMAIII, are also known inhibitors of the selenoprotein thioredoxin reductase (TrxR). Selenium, an essential micronutrient in mammals, is needed in the form of selenocysteine for activity of this enzyme and other selenoproteins. TrxR is part of a key component …

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Testing Deterrence Theory With Offenders: Assessing The Effects Of Personal And Vicarious Experience With Punishment And Punishm, Alicia Sitren Jan 2007

Testing Deterrence Theory With Offenders: Assessing The Effects Of Personal And Vicarious Experience With Punishment And Punishm, Alicia Sitren

Electronic Theses and Dissertations

Stafford and Warr (1993) reconceptualized general and specific deterrence into a single theory in which individuals' propensities to engage in criminal behavior are based on some combination of personal experiences with being punished and avoiding punishment and vicarious (or indirect) experiences with being punished and avoiding punishment. The researchers make a substantial contribution to the deterrence literature by accounting for the effect of punishment avoidance when assessing deterrence theory. Despite the theoretical appeal of this restatement, few studies have tested its empirical merit. The current study tests the applicability of Stafford and Warr's model but also addresses several key limitations …

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Modeling And Partitioning The Nucleotide Evolutionary Process For Phylogenetic And Comparative Genomic Inference, Todd Castoe Jan 2007

Modeling And Partitioning The Nucleotide Evolutionary Process For Phylogenetic And Comparative Genomic Inference, Todd Castoe

Electronic Theses and Dissertations

The transformation of genomic data into functionally relevant information about the composition of biological systems hinges critically on the field of computational genome biology, at the core of which lies comparative genomics. The aim of comparative genomics is to extract meaningful functional information from the differences and similarities observed across genomes of different organisms. We develop and test a novel framework for applying complex models of nucleotide evolution to solve phylogenetic and comparative genomic problems, and demonstrate that these techniques are crucial for accurate comparative evolutionary inferences. Additionally, we conduct an exploratory study using vertebrate mitochondrial genomes as a model …

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The Response Of A General Circulation Climate Model Tohigh Latitude Freshwater Forcing In The Atlantic Basinwith Respect Totropi, Victor Paulis Jan 2007

The Response Of A General Circulation Climate Model Tohigh Latitude Freshwater Forcing In The Atlantic Basinwith Respect Totropi, Victor Paulis

Electronic Theses and Dissertations

The current cycle of climate change along with increases in hurricane activity, changing precipitation patterns, glacial melt, and other extremes of weather has led to interest and research into the global correlation or teleconnection between these events. Examination of historical climate records, proxies and observations is leading to formulation of hypotheses of climate dynamics with modeling and simulation being used to test these hypotheses as well as making projections. Ocean currents are believed to be an important factor in climate change with thermohaline circulation (THC) fluctuations being implicated in past cycles of abrupt change. Freshwater water discharge into high-latitude oceans …

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The Relative Sensitivity Of An Olfactory Identification Deficit In Individuals With Schizotypal Personality Features, Vidyulata Kamath Jan 2007

The Relative Sensitivity Of An Olfactory Identification Deficit In Individuals With Schizotypal Personality Features, Vidyulata Kamath

Electronic Theses and Dissertations

Olfactory identification deficits have received recent attention as a potentially useful endophenotype for schizophrenia. Examination of this deficit in individuals with schizotypal personality features (SPF) offers an alternative approach to multiple confounds present when examining individuals with schizophrenia. The aim of the current study was to compare the relative sensitivity of performance on measures of olfaction identification and sustained attention to the presence of SPF. Twenty-six undergraduates were defined as having SPF based on scoring in the top 10% of the Abbreviated Schizotypal Personality Questionnaire (SPQ-B; mean age 19.6, SD = 1.1; 62% female). These individuals were compared to twenty-six …

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An Examination Of The Effectiveness Of The Adomian Decomposition Method In Fluid Dynamic Applications, Sonia Holmquist Jan 2007

An Examination Of The Effectiveness Of The Adomian Decomposition Method In Fluid Dynamic Applications, Sonia Holmquist

Electronic Theses and Dissertations

Since its introduction in the 1980's, the Adomian Decomposition Method (ADM) has proven to be an efficient and reliable method for solving many types of problems. Originally developed to solve nonlinear functional equations, the ADM has since been used for a wide range of equation types (like boundary value problems, integral equations, equations arising in flow of incompressible and compressible fluids etc...). This work is devoted to an evaluation of the effectiveness of this method when used for fluid dynamic applications. In particular, the ADM has been applied to the Blasius equation, the Falkner-Skan equation, and the Orr-Sommerfeld equation. This …

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A Cultural Contingency Leadership Model For A Multinational Higher Education Joint Venture, Frankie Albritton Jan 2007

A Cultural Contingency Leadership Model For A Multinational Higher Education Joint Venture, Frankie Albritton

Electronic Theses and Dissertations

This dissertation addressed the need for empirical research on the leadership of multinational virtual teams (Davis & Bryant, 2003; Early & Gibson, 2002; Ilgen, Lepine, and Hollenbeck, 1997; Prieto & Arias, 1997), particularly in the field of educational leadership (Cheng, 1995). This was accomplished through the development of a model based upon the cultural values discovered through the use of Hofstede's (1980, 2001) Values Survey Module 94 (VSM 94). As workers will bring values from their own cultures to the multinational workplace (Bochner & Hesketh, 1994), research was conducted to determine the cultural values of economics professors in the United …

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Resiliency In Adolescent College Students, Nancy Ahern Jan 2007

Resiliency In Adolescent College Students, Nancy Ahern

Electronic Theses and Dissertations

The construct of resilience has gained considerable attention over the last four decades since researchers observed that children and youth could cope and adapt in spite of adversity. Resilience involves a dynamic process involving an interaction between both risk and protective processes, internal and external to the individual, that can modify the effects of an adverse life event. Adolescence is considered to be a period of vulnerability for most individuals as they often partake in high risk behaviors. Further, those individuals who are in their early college years are faced with the developmental challenges of this life phase which can …

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Verification Of Pilot-Scale Iron Release Models, Stephen Glatthorn Jan 2007

Verification Of Pilot-Scale Iron Release Models, Stephen Glatthorn

Electronic Theses and Dissertations

A model for the prediction of color release from a pilot distribution system was created in 2003 by Imran. This model allows prediction of the release of color from aged cast iron and galvanized steel pipes as a function of water quality and hydraulic residence time. Color was used as a surrogate measurement for iron, which exhibited a strong linear correlation. An anomaly of this model was an absence of a term to account for pH, due to the influent water being well stabilized. A new study was completed to evaluate the effectiveness of corrosion inhibitors against traditional adjustment. Two …

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Identification And Suitability Of A Non-Anthropomorphic Meta-Language Framework In Military Applications, Gilbert Cardona Jan 2007

Identification And Suitability Of A Non-Anthropomorphic Meta-Language Framework In Military Applications, Gilbert Cardona

Electronic Theses and Dissertations

Humans carry mental models concerning the behaviors, looks, and operation of products, tools, and items used in their daily lives. When these items do not fit a user's conceptual model confusion and inefficiency occur. There are four basic types of mental models based on interactive activities: 1) instructing, 2) conversing, 3) manipulating and navigating, and 4) exploring and browsing. This thesis will focus on the conversing conceptual model and its application to communications between human-agent teams to best fit a user's mental model for that communication. A non-anthropomorphic framework does not exist for use in military applications such as; target …

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Synthesis Of Novel Aziridine Derivatives Of Podocarpic Acid, Stephen Rhoden Jan 2007

Synthesis Of Novel Aziridine Derivatives Of Podocarpic Acid, Stephen Rhoden

Electronic Theses and Dissertations

Podocarpic acid (a diterpenoid resin acid extracted from the Podocarpacea specie of plants) has shown cytotoxicity against carcinoma of the nasopharynx. Since this discovery has been made, research has been performed in order to alter the structure of the resin acid so as to increase the anticancer activity. The carboxylic acid and phenol functional groups, which are present in podocarpic acid, make it possible to synthesize new derivatives selectively at the C-15, C-13, and C-7 positions as well as by substitution of the phenol hydroxyl group. Thus numerous derivatives can be prepared, in high yield, for the purpose of investigating …

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Dimesionality Aspects Of Nano Micro Integrated Metal Oxide Based Early Stage Leak Detection Room Temperature Hydrogen Sensor, Sameer Arun Deshpande Jan 2007

Dimesionality Aspects Of Nano Micro Integrated Metal Oxide Based Early Stage Leak Detection Room Temperature Hydrogen Sensor, Sameer Arun Deshpande

Electronic Theses and Dissertations

Detection of explosive gas leaks such as hydrogen (H2) becomes key element in the wake of counter-terrorism threats, introduction of hydrogen powered vehicles and use of hydrogen as a fuel for space explorations. In recent years, a significant interest has developed on metal oxide nanostructured sensors for the detection of hydrogen gas. Gas sensors properties such as sensitivity, selectivity and response time can be enhanced by tailoring the size, the shape, the structure and the surface of the nanostructures. Sensor properties (sensitivity, selectivity and response time) are largely modulated by operating temperature of the device. Issues like instability of nanostructures …

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Optimizing The High Dynamic Range Imaging Pipeline, Ahmet Oguz Akyuz Jan 2007

Optimizing The High Dynamic Range Imaging Pipeline, Ahmet Oguz Akyuz

Electronic Theses and Dissertations

High dynamic range (HDR) imaging is a rapidly growing field in computer graphics and image processing. It allows capture, storage, processing, and display of photographic information within a scene-referred framework. The HDR imaging pipeline consists of the major steps an HDR image is expected to go through from capture to display. It involves various techniques to create HDR images, pixel encodings and file formats for storage, tone mapping for display on conventional display devices and direct display on HDR capable screens. Each of these stages have important open problems, which need to be addressed for a smoother transition to an …

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Signal Processing Of An Ecg Signal In The Presence Of A Strong Static Magnetic Field, Aditya Gupta Jan 2007

Signal Processing Of An Ecg Signal In The Presence Of A Strong Static Magnetic Field, Aditya Gupta

Electronic Theses and Dissertations

This dissertation addresses the problem of elevation of the T wave of an electrocardiogram (ECG) signal in the magnetic resonance imaging (MRI). In the MRI, due to the strong static magnetic field the interaction of the blood flow with this strong magnetic field induces a voltage in the body. This voltage appears as a superimposition at the locus of the T wave of the ECG signal. This looses important information required by the doctors to interpret the ST segment of the ECG and detect diseases such as myocardial infarction. This dissertation aims at finding a solution to the problem of …

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Fate Of Nitrogen And Phosphorus Species From A Black And Goldtm Nugget Mix In A Laboratoy Column Simulated Septic Tank Drainfiel, Timir Shah Jan 2007

Fate Of Nitrogen And Phosphorus Species From A Black And Goldtm Nugget Mix In A Laboratoy Column Simulated Septic Tank Drainfiel, Timir Shah

Electronic Theses and Dissertations

The presence of nitrates and phosphorus in ground water is a worldwide problem. A septic tank with drainfield that is conventionally designed does not typically remove nitrogen in the form of nitrates. The main risks are in "Blue baby" syndrome and suspected carcinogenic effect of nitrates on humans and the nutrient enrichment of receiving waters. In some areas nitrate and phosphorus removal are essentially required. Thus the information in this report concentrates on using media in the drainfield for the removal of nitrogen and phosphorus. Extensive work has been conducted in the past few decades in order to find suitable …

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An Economic Framework For Resource Management And Pricing In Wireless Networks With Competitive Service Providers, Shamik Sengupta Jan 2007

An Economic Framework For Resource Management And Pricing In Wireless Networks With Competitive Service Providers, Shamik Sengupta

Electronic Theses and Dissertations

A paradigm shift from static spectrum allocation to dynamic spectrum access (DSA) is becoming a reality due to the recent advances in cognitive radio, wide band spectrum sensing, and network aware real--time spectrum access. It is believed that DSA will allow wireless service providers (WSPs) the opportunity to dynamically access spectrum bands as and when they need it. Moreover, due to the presence of multiple WSPs in a region, it is anticipated that dynamic service pricing would be offered that will allow the end-users to move from long-term service contracts to more flexible short-term service models. In this research, we …

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Behavior Of Variable-Length Genetic Algorithms Under Random Selection, Harold Stringer Jan 2007

Behavior Of Variable-Length Genetic Algorithms Under Random Selection, Harold Stringer

Electronic Theses and Dissertations

In this work, we show how a variable-length genetic algorithm naturally evolves populations whose mean chromosome length grows shorter over time. A reduction in chromosome length occurs when selection is absent from the GA. Specifically, we divide the mating space into five distinct areas and provide a probabilistic and empirical analysis of the ability of matings in each area to produce children whose size is shorter than the parent generation's average size. Diversity of size within a GA's population is shown to be a necessary condition for a reduction in mean chromosome length to take place. We show how a …

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Biostability In Drinking Water Distribution Systems In A Changing Water Quality Environment Using Corrosion Inhibitors, Bingjie Zhao Jan 2007

Biostability In Drinking Water Distribution Systems In A Changing Water Quality Environment Using Corrosion Inhibitors, Bingjie Zhao

Electronic Theses and Dissertations

In this study, the bacterial growth dynamics of 14 pilot drinking water distribution systems were studied in order to observe water quality changes due to corrosion inhibitor addition. Empirical models were developed to quantity the effect of inhibitor type and dose on bacterial growth (biofilm and bulk water). Water and pipe coupon samples were taken and examined during the experiments. The coupons were exposed to drinking water at approximately 20°C for at least 5 weeks to allow the formation of a measurable quasi- steady-state biofilm. Bulk water samples were taken every week. In this study, two simple but practical empirical …

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Soliton Dynamics And Self-Induced Transparency In Nonlinear Nanosuspensions, R. El-Ganainy, D. N. Christodoulides, C. Rotschild, M. Segev Jan 2007

Soliton Dynamics And Self-Induced Transparency In Nonlinear Nanosuspensions, R. El-Ganainy, D. N. Christodoulides, C. Rotschild, M. Segev

Faculty Bibliography 2000s

We study spatial soliton dynamics in nano-particle suspensions. Starting from the Nernst-Planck and Smoluchowski equations, we demonstrate that in these systems the underlying nonlinearities as well as the nonlinear Rayleigh losses depend exponentially on optical intensity. Two different nonlinear regimes are identified depending on the refractive index contrast of the nanoparticles involved and the interesting prospect of self-induced transparency is demonstrated. Soliton stability is systematically analyzed for both 1D and 2D configurations and their propagation dynamics in the presence of Rayleigh losses is examined. The possibility of synthesizing artificial nonlinearities using mixtures of nanosuspensions is also considered.

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Fluvial Geomorphologic And Hydrodynamic Assessment In The Tidal Portion Of The Lower Rio Grande River, Us-Mexico Borderland, A. Ernest, B. Bokhim, N. B. Chang, I. J. Huang Jan 2007

Fluvial Geomorphologic And Hydrodynamic Assessment In The Tidal Portion Of The Lower Rio Grande River, Us-Mexico Borderland, A. Ernest, B. Bokhim, N. B. Chang, I. J. Huang

Faculty Bibliography 2000s

With fast population growth and economic development in the US-Mexico Borderland, water diversion and usages has reduced the flow substantially in the Low Rio Grande River (LRGR). Tidal portion of the LRGR has posed an environmental drought issue since 1993 and the channel clogged with the invasion of non-native plants also causes environmental problems. As a result of the intensity of these natural and manmade factors, the Rio Grande stopped flowing to the sea in February 2001. The flows were reduced to a point that they were unable to push out the sand deposited at the mouth. Geomorphologic evolution in …

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Adaptive Capacity And Learning To Learn As Leverage For Social-Ecological Resilience, Ioan Fazey, John A. Fazey, Joern Fischer, Kate Sherren, John Warren, Reed F. Noss, Stephen R. Dovers Jan 2007

Adaptive Capacity And Learning To Learn As Leverage For Social-Ecological Resilience, Ioan Fazey, John A. Fazey, Joern Fischer, Kate Sherren, John Warren, Reed F. Noss, Stephen R. Dovers

Faculty Bibliography 2000s

Adaptive capacity is increasingly recognized as essential for maintaining the resilience of social-ecological systems and for coping with environmental change. Four main requirements enable societies to successfully adapt to change: (1) the will and intention to maintain social-ecological resilience, (2) knowledge about current problems and the desired direction of change, (3) proactive behavior, and (4) the capacity to change existing patterns of behavior. The adaptive capacity of societies can be greatly enhanced by fostering the adaptive capacity of their individual members. Considerable knowledge about how to foster the adaptability of individuals exists in the science of education and in cognitive …

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Impact Of Trivalent Arsenicals On Selenoprotein Synthesis, Denis Ganyc, Sarah Talbot, Fanta Konate, Sarah Jackson, Brian Schanen, William Cullen, William T. Self Jan 2007

Impact Of Trivalent Arsenicals On Selenoprotein Synthesis, Denis Ganyc, Sarah Talbot, Fanta Konate, Sarah Jackson, Brian Schanen, William Cullen, William T. Self

Faculty Bibliography 2000s

BACKGROUND: Exposure to arsenic has been associated with development of skin, lung, bladder, liver, and kidney cancer. Recent evidence suggests that an increase in oxidative stress in cells treated with arsenicals represents the molecular mechanism behind arsenic-induced carcinogenesis. Selenium, in the form of selenocysteine, is necessary for the activity of several enzymes with a role in defense against reactive oxygen species. A mutual sparing effect between arsenic and selenium has been shown in animal studies when both metalloids are present in high concentrations. OBJECTIVES: To determine whether changes in selenoprotein synthesis may be an underlying mechanism behind arsenic-induced carcinogenesis, we …

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Effects Of Environmental And Land Use Regulation In The Oil And Gas Industry Using The Wyoming Checkerboard As An Experimental Design (Retraction Of Vol 92, Pg 1588, 2002), Mitch Kunce, Shelby Gerking, William Morgan Jan 2007

Effects Of Environmental And Land Use Regulation In The Oil And Gas Industry Using The Wyoming Checkerboard As An Experimental Design (Retraction Of Vol 92, Pg 1588, 2002), Mitch Kunce, Shelby Gerking, William Morgan

Faculty Bibliography 2000s

No abstract provided.

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Dune Vegetation Fertilization By Nesting Sea Turtles, Laura B. Hannan, James D. Roth, Llewellyn M. Ehrhart, John F. Weishampel Jan 2007

Dune Vegetation Fertilization By Nesting Sea Turtles, Laura B. Hannan, James D. Roth, Llewellyn M. Ehrhart, John F. Weishampel

Faculty Bibliography 2000s

Sea turtle nesting presents a potential pathway to subsidize nutrient-poor dune ecosystems, which provide the nesting habitat for sea turtles. To assess whether this positive feedback between dune plants and turtle nests exists, we measured N concentration and delta N-15 values in dune soils, leaves from a common dune plant ( sea oats [Uniola paniculata]), and addled eggs of loggerhead (Caretta caretta) and green turtles ( Chelonia mydas) across a nesting gradient ( 200 - 1050 nests/km) along a 40.5-km stretch of beach in east central Florida, USA. The delta N-15 levels were higher in loggerhead than green turtle eggs, …

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An Ultra-High Discrimination Y Chromosome Short Tandem Repeat Multiplex Dna Typing System, Erin K. Hanson, Jack Ballantyne Jan 2007

An Ultra-High Discrimination Y Chromosome Short Tandem Repeat Multiplex Dna Typing System, Erin K. Hanson, Jack Ballantyne

Faculty Bibliography 2000s

In forensic casework, Y chromosome short tandem repeat markers (Y-STRs) are often used to identify a male donor DNA profile in the presence of excess quantities of female DNA, such as is found in many sexual assault investigations. Commercially available Y-STR multiplexes incorporating 12-17 loci are currently used in forensic casework (Promega's PowerPlex (R) Y and Applied Biosystems' AmpF/STR (R) Yfiler (R)). Despite the robustness of these commercial multiplex Y-STR systems and the ability to discriminate two male individuals in most cases, the coincidence match probabilities between unrelated males are modest compared with the standard set of autosomal STR markers. …

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Gene Expression And The Evolution Of Phenotypic Diversity In Social Wasps, Eric A. Hoffman, Michael Ad Goodisman Jan 2007

Gene Expression And The Evolution Of Phenotypic Diversity In Social Wasps, Eric A. Hoffman, Michael Ad Goodisman

Faculty Bibliography 2000s

Background: Organisms are capable of developing different phenotypes by altering the genes they express. This phenotypic plasticity provides a means for species to respond effectively to environmental conditions. One of the most dramatic examples of phenotypic plasticity occurs in the highly social hymenopteran insects ( ants, social bees, and social wasps), where distinct castes and sexes all arise from the same genes. To elucidate how variation in patterns of gene expression affects phenotypic variation, we conducted a study to simultaneously address the influence of developmental stage, sex, and caste on patterns of gene expression in Vespula wasps. Furthermore, we compared …

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Individual Identification Of Polar Bears By Whisker Spot Patterns, Carlos Anderson Jan 2007

Individual Identification Of Polar Bears By Whisker Spot Patterns, Carlos Anderson

Electronic Theses and Dissertations

Many types of ecological studies require identification of individual animals. I developed and evaluated an automated identification system for polar bears (Ursus maritimus) based on their whisker spot patterns. First, I measured the reliability of using whisker spot patterns for identification from polar bear photographs taken in western Hudson Bay. This analysis involved estimating the complexity of each whisker spot pattern in terms of its information content. I found that 98% of patterns contained enough information to be reliable, and this result varied little among three different observers. Based on these results, I implemented a computer-aided identification system for polar …

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Modeling Free Chlorine And Chloramine Decay In A Pilot Distribution System, Jorge Miguel Arevalo Jan 2007

Modeling Free Chlorine And Chloramine Decay In A Pilot Distribution System, Jorge Miguel Arevalo

Electronic Theses and Dissertations

The purpose of this study was to identify the effect that water quality, pipe material, pipe size, flow conditions and the use of corrosion inhibitors would have on the rate of free chlorine and chloramine decay in distribution systems. Empirical models were developed to predict the disinfectant residual concentration with time based on the parameters that affected it. Different water treatment processes were used to treat groundwater and surface water to obtain 7 types of finished waters with a wide range of water quality characteristics. The groundwater was treated either by conventional treatment by aeration (G1) or softening (G2) or …

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Impact Of Zinc Orthophosphate Inhibitor On Distribution System Water Quality, Xiaotao Guan Jan 2007

Impact Of Zinc Orthophosphate Inhibitor On Distribution System Water Quality, Xiaotao Guan

Electronic Theses and Dissertations

This dissertation consists of four papers concerning impacts of zinc orthophosphate (ZOP) inhibitor on iron, copper and lead release in a changing water quality environment. The mechanism of zinc orthophosphate corrosion inhibition in drinking water municipal and home distribution systems and the role of zinc were investigated. Fourteen pilot distribution systems (PDSs) which were identical and consisted of increments of PVC, lined cast iron, unlined cast iron and galvanized steel pipes were used in this study. Changing quarterly blends of finished ground, surface and desalinated waters were fed into the pilot distribution systems over a one year period. Zinc orthophosphate …

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Processing And Study Of Carbon Nanotube / Polymer Nanocomposites And Polymer Electrolyte Materials, Muthuraman Harish Jan 2007

Processing And Study Of Carbon Nanotube / Polymer Nanocomposites And Polymer Electrolyte Materials, Muthuraman Harish

Electronic Theses and Dissertations

The first part of the study deals with the preparation of carbon nanotube/polymer nanocomposite materials. The dispersion of multi-walled carbon nanotubes (MWNTs) using trifluoroacetic acid (TFA) as a co-solvent and its subsequent use in polymer nanocomposite fabrication is reported. The use of carbon nanotube/ polymer nanocomposite system for the fabrication of organic solar cells is also studied. TFA is a strong but volatile acid which is miscible with many commonly used organic solvents. Our study demonstrates that MWNTs can be effectively purified and readily dispersed in a range of organic solvents including dimethyl formamide (DMF), tetrahydrofuran (THF), and dichloromethane when …

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