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Articles 4591 - 4620 of 7872
Full-Text Articles in Entire DC Network
Central Florida Future, Vol. 39 No. 75, March 26, 2007
Central Florida Future, Vol. 39 No. 75, March 26, 2007
Central Florida Future
No abstract provided.
Central Florida Future, Vol. 39 No. 74, March 23, 2007
Central Florida Future, Vol. 39 No. 74, March 23, 2007
Central Florida Future
No abstract provided.
Central Florida Future, Vol. 39 No. 73, March 21, 2007
Central Florida Future, Vol. 39 No. 73, March 21, 2007
Central Florida Future
No abstract provided.
Central Florida Future, Vol. 39 No. 71, March 9, 2007
Central Florida Future, Vol. 39 No. 71, March 9, 2007
Central Florida Future
No abstract provided.
Central Florida Future, Vol. 39 No. 69, March 5, 2007
Central Florida Future, Vol. 39 No. 69, March 5, 2007
Central Florida Future
No abstract provided.
Central Florida Future, Vol. 39 No. 66, February 26, 2007
Central Florida Future, Vol. 39 No. 66, February 26, 2007
Central Florida Future
No abstract provided.
Central Florida Future, Vol. 39 No. 64, February 21, 2007
Central Florida Future, Vol. 39 No. 64, February 21, 2007
Central Florida Future
No abstract provided.
Agile Spectral Interferometric Microscopy, Nabeel Riza, Amana Bokhari, Frank Perez
Agile Spectral Interferometric Microscopy, Nabeel Riza, Amana Bokhari, Frank Perez
UCF Patents
An agile optical sensor based on spectrally agile heterodyne optical interferometric confocal microscopy implemented via an ultra-stable in-line acousto-optic tunable filter (AOTF) based interferometer using double anisotropic acousto-optic Bragg diffraction. One embodiment uses a tunable laser as the light source while other embodiments use a broadband source or a fixed wavelength laser as the source. One embodiment uses anisotropic diffractions in an AOTF to generate two near-collinear orthogonal linear polarization and slightly displaced beams that both pass via a test sample to deliver highly sensitive sample birefringence or material optical retardation measurements. A spherical lens is used to form focused …
Central Florida Future, Vol. 39 No. 60, February 12, 2007
Central Florida Future, Vol. 39 No. 60, February 12, 2007
Central Florida Future
No abstract provided.
Moisture Barrier Cone, John Holmquist, Par Axelsson, Alejandro Mancuso, Par Ostberg
Moisture Barrier Cone, John Holmquist, Par Axelsson, Alejandro Mancuso, Par Ostberg
UCF Patents
Closed air space devices and methods of use for full body bio hazard type suits that eliminate condensation and fogging from forming on the face masks and the window visor of the suit. The devices and methods have a sealed closed air space that can be formed from flexible see-through plastic in a cone shape that can be sealed between the mask and their visor. The closed air space can be presealed tot he visor/outer wall of the suit and have a second end fitted with an elastic type band that allows the wearer to attach and detach the closed …
Sandspur, Vol 113, No 15, January 29, 2007, Rollins College
Sandspur, Vol 113, No 15, January 29, 2007, Rollins College
The Rollins Sandspur
Rollins College student newspaper, written by the students and published at Rollins College. The Sandspur started as a literary journal.
Central Florida Future, Vol. 39 No. 53, January 26, 2007
Central Florida Future, Vol. 39 No. 53, January 26, 2007
Central Florida Future
No abstract provided.
Central Florida Future, Vol. 39 No. 51, January 22, 2007
Central Florida Future, Vol. 39 No. 51, January 22, 2007
Central Florida Future
No abstract provided.
Central Florida Future, Vol. 39 No. 50, January 19, 2007
Central Florida Future, Vol. 39 No. 50, January 19, 2007
Central Florida Future
No abstract provided.
Central Florida Future, Vol. 39 No. 46, January 8, 2007
Central Florida Future, Vol. 39 No. 46, January 8, 2007
Central Florida Future
No abstract provided.
Identification Of Genes Encoding Acyl-Coa Reductases And Aldehyde Reductases In Mycobacterial Genome By Characterization Of The Reductases Expressed In E. Coli, Harminder Singh
Electronic Theses and Dissertations
Mycobacterium tuberculosis has been long known to produce wax esters. However, the enzymes involved in their biosynthesis have not been identified. Here we report the identification of Rv3391 and Rv1543 as genes that encode fatty acyl-CoA reductases and Rv1544 as one that encodes an aldehyde reductase. When expressed in E.coli, the products of Rv3391 and Rv1543 catalyzed reduction of fatty acyl-CoA to fatty alcohol with the corresponding aldehyde as an intermediate with an optimal pH of 7.0. Both enzymes showed a strong preference for NADPH over NADH as a reductant. Apparent Km for NADPH was 38 [micro]M for Rv3391 product …
Social Pathogenic Sources Of Poor Community Health, Hayden Smith
Social Pathogenic Sources Of Poor Community Health, Hayden Smith
Electronic Theses and Dissertations
The United States currently provides a health care system that is neither efficient nor equitable. Despite outspending the world on health care, over three-fourths of developed countries produce better health outcomes (Auerbach et al., 2000). Simultaneously, the "Ecological School of Thought" has documented the large impact that social, economic, and environmental circumstances play in health outcomes. Unfortunately, these 'ecological" studies are frequently conducted without theoretical justification, and rely solely on a cross-sectional research design and a myriad of unrelated variables. This study represents an important step towards the development of a true theory of "ecology". More specifically, we argue that …
Correlation Of Rpob Gene Mutation With Clinical Rifabutin And Rifampicin Resistance For Treatment Of Crohn's Disease, Daniel Beckler
Correlation Of Rpob Gene Mutation With Clinical Rifabutin And Rifampicin Resistance For Treatment Of Crohn's Disease, Daniel Beckler
Electronic Theses and Dissertations
Emerging rise in microbial drug resistance and the slow-growing characteristic of some intracellular pathogens such as MAP (Mycobacterium avium subspecies paratuberculosis) strongly urges the need for an effective approach for unconventional drug susceptibility testing. We designed a molecular-based PCR method for the evaluation of rifabutin (RFB) and rifampicin (RIF) resistance based on probable determinant regions within the rpoB gene of MAP, including the 81 bp variable site located between nucleotides 1363 and 1443. The minimum inhibitory concentration (MIC) for RIF was also determined against 10 MAP isolates in attempt to seek correlation with rpoB sequences. We determined that MAP strain …
Mechanism Of Action And Regulation Of Membrane Serine Protease Prostasin In The Prostate And Prostate Cancer, Mengqian Chen
Mechanism Of Action And Regulation Of Membrane Serine Protease Prostasin In The Prostate And Prostate Cancer, Mengqian Chen
Electronic Theses and Dissertations
The glycosylphosphatidylinositol (GPI)-anchored serine protease prostasin (PRSS8) is expressed at the apical membrane surface of epithelial cells and acts as a suppressor of tumor invasion when re-expressed in highly invasive human prostate and breast cancer cell lines. To better understand the molecular mechanisms underlying the anti-invasion phenotype associated with prostasin re-expression in prostate cancer cells, we expressed wild-type human prostasin or a serine active-site mutant prostasin in the PC-3 human prostate carcinoma cells. Molecular changes were measured at the mRNA and the protein levels. The expression of several invasion-promoting molecules is regulated by prostasin re-expression, mediated by a protein-level down-regulation …
A Member Of The Novel Fikk Family Of Plasmodium Falciparum Putative Protein Kinases Exhibits Diacylglycerol Kinase Activity And Is Exported To The Host Erythrocyte, David Floyd Curtis
A Member Of The Novel Fikk Family Of Plasmodium Falciparum Putative Protein Kinases Exhibits Diacylglycerol Kinase Activity And Is Exported To The Host Erythrocyte, David Floyd Curtis
Electronic Theses and Dissertations
Plasmodium falciparum is one of four species known to cause malaria in humans and is the species that is associated with the most virulent form of the disease. Malaria causes nearly two million deaths each year, many of these occurring among children in under-developed countries of the world. One reason for this is the prevalence of drug resistant strains of malaria that mitigate the efficacy of existing drugs. Hence, the identification of a new generation of pharmacological agents for malaria is extremely urgent. The recent identification of a group of novel protein kinases within the Plasmodium falciparum genome has provided …
The Generation And Scavenging Of Radicals Via Cerium And Nanoceria, Eric Glenn Heckert
The Generation And Scavenging Of Radicals Via Cerium And Nanoceria, Eric Glenn Heckert
Electronic Theses and Dissertations
Cerium is the most abundant of the rare earth metals, found on average at a level of 66 parts per million in the earth's crust. The unique redox properties of cerium and cerium oxide nanoparticles have led to its use in a wide variety of industrial and commercial uses such as oxygen sensors, fertilizers and as a catalyst to remove toxic gases in automobile exhaust. The use of cerium has also garnered interest in the nanotechnology field. Nanoceria has been generated in its oxide form as nanoparticles and nanorods. Recently, nanoceria has been shown to protect against oxidative stress in …
Seasonal And Diel Patterns Of Manatee Habitat Use, Monica Ann Ross
Seasonal And Diel Patterns Of Manatee Habitat Use, Monica Ann Ross
Electronic Theses and Dissertations
State and Federal agencies have created sanctuaries and speed zones to help reduce manatee mortality while incorporating the recreational and commercial resource needs of these same habitats for humans. Specific habitat resources are considered necessary to increase manatee survivorship. We have only recently begun to address how manatees use some of these resources based on physiological or reproductive strategies. In this study, I quantified patterns of habitat use during seasonal and diel periods for different sex and reproductive manatee classes using data from a radio-telemetry study conducted by the Florida Fish and Wildlife Conservation Commission during 1991-1996. I used five …
Mechanisms Promoting Phosphorylation Of The Nf2 Tumor Suppressor And Its Effects On Schwann Cell Development, Courtney Lynn Thaxton
Mechanisms Promoting Phosphorylation Of The Nf2 Tumor Suppressor And Its Effects On Schwann Cell Development, Courtney Lynn Thaxton
Electronic Theses and Dissertations
Neurofibromatosis type 2 is an autosomal dominant disease characterized by the formation of schwannomas and other peripheral neuropathies. The nf2 gene encodes the protein Schwannomin, or merlin. Schwannomin (Sch) is a membrane-cytoskeletal linking protein that suppresses cell proliferation at high cell density and modulates cell shape. Sch's tumor suppressive activity is regulated by its localization, conformation, and phosphorylation at serine 518 (S518). Sch's localization is dependent on binding the scaffold protein, paxillin. Phosphorylation of Sch at S518 regulates its conformation and tumor suppressor function. In a negative feedback loop, unphosphorylated Sch restricts cell proliferation downstream of Rac and p21-activated kinase …
University Of Central Florida Ir 2006-2007 Fact Book, University Of Central Florida
University Of Central Florida Ir 2006-2007 Fact Book, University Of Central Florida
Historical Fact Book and Enrollment
Historical fact book and enrollment data for the University of Central Florida.
Physical Characteristics Of An Individual: The Identification Of Biomarkers For Biological Age Determination, Michelle Alvarez
Physical Characteristics Of An Individual: The Identification Of Biomarkers For Biological Age Determination, Michelle Alvarez
Electronic Theses and Dissertations
It is now a matter of routine for the forensic scientist to obtain the genetic profile of an individual from DNA recovered from a biological stain deposited at a crime scene. Potential contributors of the stain must either be known to investigators (i.e. a developed suspect) or the questioned profile must be searched against a database of DNA profiles such as those maintained in the CODIS National DNA database. However, in those instances where there is no developed suspect and no match is obtained after interrogation of appropriate DNA databases, the DNA profile per se presently provides no meaningful information …
Using Computer Simulation Modeling To Evaluate The Bioterrorismresponse Plan At A Local Hospital Facility, Robert Bebber
Using Computer Simulation Modeling To Evaluate The Bioterrorismresponse Plan At A Local Hospital Facility, Robert Bebber
Electronic Theses and Dissertations
The terrorist attacks of September 11th, 2001 and the subsequent anthrax mail attack have forced health care administrators and policy makers to place a new emphasis on disaster planning at hospital facilities--specifically bioterrorism planning. Yet how does one truly "prepare" for the unpredictable? In spite of accreditation requirements, which demand hospitals put in to place preparations to deal with bioterrorism events, a recent study from the General Accounting Office (GAO) concluded that most hospitals are still not capable of dealing with such threats (Gonzalez, 2004). This dissertation uses computer simulation modeling to test the effectiveness of bioterrorism planning at a …
Glutamate Excitotoxicity In Epilepsy And Ischemia, Mangala Meenakshi Soundarapandian
Glutamate Excitotoxicity In Epilepsy And Ischemia, Mangala Meenakshi Soundarapandian
Electronic Theses and Dissertations
'Excitotoxicity' represents the excitatory amino acid mediated degeneration of neurons. Glutamate is the major excitatory neurotransmitter in the brain. Glutamate excitotoxicity has been implicated in a number of neurodegenerative disorders like Stroke, Epilepsy, Alzheimer's disease and traumatic brain injury. This neurotoxicity is summed up by the 'glutamate hypothesis' which describes the cause of neuronal cell death as an excessive release of glutamate causing over excitation of the glutamate receptors and subsequent increase in influx of calcium leading to cell death. An effort to counteract this neurotoxicity has lead to the development of glutamate receptor antagonists that can effectively serve as …
Lim Kinase 1 Modulates Expression Of Matrix Metalloproteinases And Associates With Gamma-Tubulin: Dual Role In Invasion And Mito, Tenekua Tapia
Lim Kinase 1 Modulates Expression Of Matrix Metalloproteinases And Associates With Gamma-Tubulin: Dual Role In Invasion And Mito, Tenekua Tapia
Electronic Theses and Dissertations
LIM kinase 1 (LIMK1) is a unique dual specificity serine/threonine kinase containing two N-terminal LIM domains in tandem, a PDZ domain and a C-terminal catalytic domain. LIMK1 is involved in modulation of actin cytoskeleton through inactivating phosphorylation of the ADF (actin depolymerization factor) family protein cofilin. Recent studies have shown that LIMK1 is upregulated in breast and prostate cancer cells and tissues, promotes metastasis in animals and induces acquisition of an invasive phenotype when ectopically expressed in benign prostate epithelial (BPH) cells. Furthermore, overexpression of LIMK1 was associated with altered sub cellular localization of the membrane type 1 matrix metalloprotease …
Helical Packing Regulates Structural Transitions In Bax, Nuska Tschammer
Helical Packing Regulates Structural Transitions In Bax, Nuska Tschammer
Electronic Theses and Dissertations
Apoptosis is essential for development and the maintenance of cellular homeostasis and is frequently dysregulated in disease states. Proteins of the BCL-2 family are key modulators of this process and are thus ideal therapeutic targets. In response to diverse apoptotic stimuli, the pro-apoptotic member of BCL-2 family, BAX, redistributes from the cytosol to the mitochondria or endoplasmic reticulum and primes cells for death. The structural changes that enable this lethal protein to transition from a cytosolic form to a membrane-bound form remain poorly understood. Elucidating this process is a necessary step in the development of BAX as a novel therapeutic …
Retrocyclin Rc-101 Overcomes Cationic Mutations On The Heptad Repeat 2 Of Hiv-1 Gp41, Christopher Fuhrman
Retrocyclin Rc-101 Overcomes Cationic Mutations On The Heptad Repeat 2 Of Hiv-1 Gp41, Christopher Fuhrman
Electronic Theses and Dissertations
Retrocyclin RC-101, a θ-defensin with lectin-like properties, potently inhibits infection by many HIV-1 subtypes by binding to the heptad repeat (HR)-2 region of gp41 and preventing six-helix bundle formation. In the present study, we used in silico computational exploration to identify residues of HR2 that interacted with RC-101 and then analyzed the HIV-1 Sequence Database at LANL for residue variations in the HR1 and HR2 segments that could plausibly impart in vivo resistance. Docking RC-101 to gp41 peptides in silico confirmed its strong preference for HR2 over HR1, and implicated residues crucial for its ability to bind HR2. We mutagenized …