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'But George Floyd Wasn't A Saint': A Critical Discourse Analysis Pre And Post George Floyd, Raya Berkley-Jacobs
'But George Floyd Wasn't A Saint': A Critical Discourse Analysis Pre And Post George Floyd, Raya Berkley-Jacobs
Graduate Studies Theses and Dissertations 2026
May 25, 2020, George Floyd died at the hands of former police officer Derek Chauvin after he placed his knee on George Floyd’s neck for 8 minutes and 46 seconds. His death sparked outrage, protests, and calls for accountability, justice, and reform. This study addresses the impact of George Floyd’s death as a focusing event that created a policy window under which federal legislation was introduced as a response to his death. Drawing on Punctuated Equilibrium Theory and Social Construction Theory, the study utilizes a critical discourse analysis to test how the death of George Floyd impacted the amount and …
Ecological And Evolutionary Divergence Of A Shared Sympatric Color Polymorphism In Paracirrhites Hawkfish, Samuel Greaves
Ecological And Evolutionary Divergence Of A Shared Sympatric Color Polymorphism In Paracirrhites Hawkfish, Samuel Greaves
Graduate Studies Theses and Dissertations 2026
Color polymorphism provides a tractable window into how selection, gene flow, and ecology interact to maintain phenotypic diversity and initiate divergence. I investigate the ecological and genomic basis of sympatric light and melanistic morphs in two reef hawkfishes, Paracirrhites arcatus and P. hemistictus, across Guam and Hawai‘i. This study aims to determine whether the color morphs of these hawkfishes are a stable polymorphism or have begun the process of ecological speciation. For P. arcatus revealed substantially lower density on Guam (0.086 ind/m²) than reported for Hawai‘i (0.292 ind/m²) and a strong skew away from the melanistic morph on Guam …
Cell Type-Specific Fatty Acid Signalling And Its Sex Dependence, Emeline Masterson
Cell Type-Specific Fatty Acid Signalling And Its Sex Dependence, Emeline Masterson
Graduate Studies Theses and Dissertations 2026
Dietary fat is a highly palatable, energy-dense nutrient whose oral detection powerfully shapes ingestion patterns and metabolic outcomes. Despite clear behavioral and physiological evidence that fat can evoke distinct taste signals, the cellular and molecular mechanisms underlying its transduction remain poorly understood. A critical gap exists in our understanding of the cell-type-specific molecular pathways and how these signals are modulated by hormonal status. This dissertation delineates estrogen-dependent plasticity in FA transduction within the peripheral taste system, revealing coordinated, sex and cell-type-specific modulation of these pathways. To understand the missing mechanisms, FA-evoked responses were compared in Type II cells from wild-type …
The Effects Of Episodic Facilitation And Immersion On Memory Formation During Learning Of An Exterior Preflight Inspection Procedure, Nathan A. Sonnenfeld
The Effects Of Episodic Facilitation And Immersion On Memory Formation During Learning Of An Exterior Preflight Inspection Procedure, Nathan A. Sonnenfeld
Graduate Studies Theses and Dissertations 2026
This research examined the use of episodic facilitation—instructional elements aligned with episodic memory (EM) processes—to affect learners’ memory of simulation training for an aviation procedure. Despite its assumed benefits in industry and theory, virtual reality (VR) has shown limited advantages over conventional media for training procedures, in part because prevailing frameworks emphasize semantic and procedural outcomes, leaving memory of training experiences as events underexamined. To address this gap, this work advances human factors research by examining EM as a design consideration, an outcome, and an explanatory mechanism for how simulation training experiences are remembered. Grounded in theories of EM and …
Reclaiming The Self: A Visual Narrative Of A Process Of Individuation Through Artistic Practice, Stacie Becker
Reclaiming The Self: A Visual Narrative Of A Process Of Individuation Through Artistic Practice, Stacie Becker
Graduate Studies Theses and Dissertations 2026
Reclaiming the Self: A Visual Narrative of a Process of Individuation Through Artistic Practice features a multidisciplinary practice that uses visual narrative, metaphor, and symbolism to reconcile the complex intersections of internal and external identity-shaping experiences, informed by lived experience as a woman. Working across painting, mixed media, printmaking, book arts, sculpture, and restorative medical tattooing, the artist dissects the tension between internal identity and external expectations, addressing themes of gender roles, relationships, trauma, and agency. Various artistic methods serve not only as a process but also as a parallel for reclaiming, healing, and restoring an authentic, unashamed sense of …
From Motherhood To Sisterhood: Women Strike For Peace And The Transmission Of Feminist Consciousness, Olivia R. Aldrich
From Motherhood To Sisterhood: Women Strike For Peace And The Transmission Of Feminist Consciousness, Olivia R. Aldrich
Graduate Studies Theses and Dissertations 2026
Women Strike for Peace (WSP) has traditionally been understood as a maternalist peace movement that emerged in response to atmospheric nuclear testing during the early Cold War era. This thesis argues that WSP’s history reveals a more nuanced relationship between motherhood, feminism, and political activism than existing scholarship has suggested. Rather than operating in distinct stages, maternalism and feminism operated simultaneously, working alongside one another throughout the organization’s history. Furthermore, this thesis builds upon Ednie Kaeh Garrison’s concept of feminist “radio waves,” arguing that WSP functioned as a transmitter of feminist consciousness, where ideas, organizational practices, and different political identities …
Laser Beam Shaping Using A Neural Network, Azeem A. Hakim
Laser Beam Shaping Using A Neural Network, Azeem A. Hakim
Honors Undergraduate Theses
Multiphoton lithography (MPL) is a method of laser-based 3D-printing for fabricating micron-scale structures point-by-point in a photopolymerizable medium. MPL’s high-resolution capabilities have made it a powerful method for the fabrication of many devices, such as microelectromechanical systems (MEMS) and tissue scaffolds. The throughput of MPL processes can be increased by using spatially shaped laser beams that expose large areas or volumes simultaneously. A laser beam can be reshaped by passing it through a spatial light modulator (SLM) displaying a pre-designed phase mask. One type of laser beam profile used for this purpose is the Bessel beam, a type of structured …
The Effects Of Stress-Related Hormones On Excitatory Synapse Formation, Autumn C. Garvey
The Effects Of Stress-Related Hormones On Excitatory Synapse Formation, Autumn C. Garvey
Honors Undergraduate Theses
Stress profoundly influences brain function through neuromodulatory hormones that regulate synaptic plasticity, yet how temporal patterns of hormone exposure shape excitatory synapse formation remains poorly understood. This study investigates how exposure to stress hormones, norepinephrine and cortisol, affects excitatory synapse development. While existing research primarily compares concentration models, real-world stress occurs in variable patterns that may produce distinct neural outcomes. To address this gap, differentiated Neuro2A neuronal cells are exposed to norepinephrine or cortisol under a continuous treatment paradigm designed to model chronic stress conditions. Following treatment, immunofluorescence imaging is utilized to quantify excitatory synapse formation through analysis of presynaptic …
Comparative Analysis Of Serum-Free Culture Conditions On Cell Proliferation And Extracellular Vesicle Production By Adipose-Derived Stem Cells, Ayna Ghulldu
Honors Undergraduate Theses
Adipose-derived stem cells (ADSCs) are promising candidates in regenerative medicine due to their proliferative capacity, self-renewal, and secretion of extracellular vesicles (EVs) that mediate intercellular communication. Serum-free media has been increasingly explored for MSC culture as it eliminates xenogeneic components, improving human therapeutic suitability. However, comparative evaluation of distinct serum-free formulations on ADSC proliferation and EV output simultaneously remains limited. This study compares a serum-containing medium to three proprietary serum-free media prototypes differing in composition, including the presence or absence of extracellular matrix proteins, to inform the optimization of culture conditions for clinical use. Proliferation, EV characteristics, and gene expression …
The Depuration Of Microplastic Pollution In Aquacultured Indian River Lagoon Oysters, Lee Nguyen
The Depuration Of Microplastic Pollution In Aquacultured Indian River Lagoon Oysters, Lee Nguyen
Honors Undergraduate Theses
Plastics are widely used in consumer goods and industrial manufacturing, and their degradation into microplastics (MP, size < 5 mm) has created an emergent environmental pollutant. Plastics readily enter aquatic environments, where they accumulate additional contaminants and bioaccumulate in organisms. While MP contamination in marine ecosystems is well documented, less is known about MP presence in aquacultured shellfish. Depuration, the process of purging contaminants from shellfish, is conducted in sterile seawater without food, which may cause oyster starvation and death. To date, MP depuration has not been examined in the aquacultured eastern oyster (Crassostrea virginica) in published studies. This study had 3 goals: 1) evaluate the effects of algal feed on oyster survival during depuration, 2) determine the effect of algal feed on depuration effectiveness, and 3) investigate the effect of a ten-day depuration on MP concentration in aquacultured C. virginica soft tissue. MP were quantified in oyster tissues, biodeposits, and in industrial algal feed. Tissues were digested using alkaline solutions, manually examined via microscopy, and analyzed using Fourier-Transform Infrared Spectroscopy (FTIR) to investigate MP polymer …
The Impact Of Gastric Sleeve And Roux-En-Y Gastric Bypass On Chief Cell Function And Protein Digestion In Obese Patients, Garikoitz Mikel Gainza
The Impact Of Gastric Sleeve And Roux-En-Y Gastric Bypass On Chief Cell Function And Protein Digestion In Obese Patients, Garikoitz Mikel Gainza
Honors Undergraduate Theses
Obesity has become one of the largest global health concerns of the 21st century, correlating with numerous associated diseases. To help address the growing prevalence and burden of obesity, sleeve gastrectomy and Roux-en-Y gastric bypass have become two commonly performed surgical procedures done to promote weight loss by altering the anatomical structure of the stomach and surrounding organs of the gastrointestinal system. Although the benefits of improved metabolism linked to these surgical procedures are well studied, their impact on the physiology of gastric cells, and more specifically chief cells as they relate to protein digestion post-surgery, is yet to …
Examining The Results Of Revolutions In The Third World: A Case Study Of The Iranian, Libyan, And Nicaraguan Revolutions, Noah A. Mohammedelamien
Examining The Results Of Revolutions In The Third World: A Case Study Of The Iranian, Libyan, And Nicaraguan Revolutions, Noah A. Mohammedelamien
Honors Undergraduate Theses
This thesis examines the post-revolutionary trajectories of Libya, Iran, and Nicaragua to explain why some Third World revolutionary projects preserve and use elements of their founding ideology while others fragment, personalize, or diffuse over time. Rather than focusing on the causes of revolution alone, it analyzes the durability of religious-socialist ideological continuity after revolutionary upheaval. Using a (MDSD) comparative historical and institutional approach grounded in primary and secondary sources, the study evaluates five key dimensions across the cases: religious-socialist ideological fusion, religious elite loyalty, popular religious mobilization, institutional embedding of ideology, and external pressure. The findings suggest ideological continuity is …
Noninvasive Monitoring Techniques: The Use Of Scat-Sourced Dna And Camera Traps To Monitor Mammalian Carnivore Species At The Ucf Arboretum, Zachary Montealegre
Noninvasive Monitoring Techniques: The Use Of Scat-Sourced Dna And Camera Traps To Monitor Mammalian Carnivore Species At The Ucf Arboretum, Zachary Montealegre
Honors Undergraduate Theses
The 800-acre University of Central Florida Arboretum Natural Lands functions as a conservation area, recreational space, and research site, making it essential to understand the ecological community it supports. Traditional wildlife monitoring methods such as mark-recapture and blood sampling can be effective but may stress animals or disrupt natural behaviors. To minimize these impacts, this study used non-invasive techniques, specifically scat-based DNA analysis and camera trapping, to assess carnivore species' presence. Two ecologically similar sites within the Arboretum were selected. Suspected carnivore scat was collected twice weekly over two months using both structured and opportunistic sampling. DNA was extracted, amplified, …
Associations Between Oral Hormonal Contraceptive Use, Digestive And Other Health Symptoms In Young Women, Silviana E. Buzatu
Associations Between Oral Hormonal Contraceptive Use, Digestive And Other Health Symptoms In Young Women, Silviana E. Buzatu
Honors Undergraduate Theses
Oral hormonal contraceptives (OHCs) are widely used among reproductive-age women; however, their gastrointestinal (GI) side effects remain understudied. The present study examined associations between OHC use, GI, physical, and psychological symptom burden in a large sample of undergraduate women. Participants (N = 669) aged 18 to 25 years were recruited from UCF’s SONA system and classified into three groups based on self-reported contraceptive status: no birth control, combined estrogen–progestin OHC, and progestin-only OHC. Participants completed GI questionnaires, as well as physical and mental health symptoms ones.
Multivariate analyses indicated that overall GI symptom profiles did not differ significantly by birth …
Repurposing Cyclin-Dependent Kinase Inhibitors For The Discovery Of Novel Antiplasmodial Compounds, Ritam Bhowmik
Repurposing Cyclin-Dependent Kinase Inhibitors For The Discovery Of Novel Antiplasmodial Compounds, Ritam Bhowmik
Honors Undergraduate Theses
Malaria remains a major global health burden with over 282 million cases annually and rising resistance to artemisinin-based combination therapies. Plasmodium falciparum, the most lethal malaria parasite species in humans, relies on tightly regulated cell cycle progression during replication within red blood cells. Cyclin-dependent kinases (CDKs) are central regulators of eukaryotic cell division and transcription, and several CDK-like enzymes in P. falciparum, including Pfmrk and PfPK6, are essential for parasite growth and structurally distinct from human kinases. This study evaluated whether commercially available human CDK inhibitors (CDKIs) targeting cancer pathways could be repurposed as novel antimalarial compounds. A library of …
Manuka Honey Modulates Oxidative Stress In Neuro2-A Cells Through Mitochondrial Regulation, Rachel Abramovici
Manuka Honey Modulates Oxidative Stress In Neuro2-A Cells Through Mitochondrial Regulation, Rachel Abramovici
Honors Undergraduate Theses
Manuka honey is known for its vital usage in wound healing, being an agonist towards fighting infections, and is an acting antioxidant [32]. Its main constituents are flavonoids and phenolic compounds, with methyl syringate (MSYR) being a major active ingredient. The specific compounds responsible for these antioxidant effects, particularly in the CNS, remain unclear. It is hypothesized that pre-treatment of mouse neuroblastoma cells with MSYR followed by hydrogen peroxide exposure will activate the AMPK/SIRT1/PGC-1a pathway, due to MSYR’s phenolic structure, and thus reduce oxidative stress and improve mitochondrial biogenesis. Hydrogen peroxide is a standard reactive oxygen species (ROS) treatment to …
Transforming Florida Chemistry Education: Exploring Information Literacy Strategies From Singapore, Han N. Le
Transforming Florida Chemistry Education: Exploring Information Literacy Strategies From Singapore, Han N. Le
Honors Undergraduate Theses
This study explores the applicability of Singapore’s information literacy (IL) strategies within Central Floridian higher education environments. Singapore’s national IL framework, supported by its Ministry of Education, integrates information and communication technology (ICT), professional development, and lifelong learning initiatives through a standardized, systemwide approach. In contrast, IL instruction in the United States is largely decentralized, often limited to one-time sessions or elective courses. To investigate the feasibility of adapting Singapore’s practices, surveys were distributed to faculty and librarians across Florida’s twelve public universities, yielding responses that highlighted varying levels of IL integration, limited institutional support, and minimal professional training related …
Multicomponent Deoxyribozyme Probes For Targeted Detection Of Cancer Associated Gene Insertions, Samuel R. Veleke
Multicomponent Deoxyribozyme Probes For Targeted Detection Of Cancer Associated Gene Insertions, Samuel R. Veleke
Honors Undergraduate Theses
Insertions and deletions (indels) in DNA sequences of genes are linked with cancers such as glioblastoma (GB). Thus, indels may be used as potential cancer biomarkers. In the NANOG gene, its pseudogene NANOGP8 has a 22 base pair insertion sequence for GB patients. In this work, the NANOG gene and the insertion sequence were detected in one sample using a dual-fluorescent assay containing two multicomponent split deoxyribozyme (Dz) probe complexes. One complex used TXR fluorescence to detect the gene regardless of the insertion’s presence. The other complex used fluorescein (FAM) fluorophore to detect the insertion. The probes were able to …
Slay Her: The Rhetoric Of Violation In Buffy The Vampire Slayer, Lea N. Wright
Slay Her: The Rhetoric Of Violation In Buffy The Vampire Slayer, Lea N. Wright
Honors Undergraduate Theses
This research draws on feminist theory and monster theory to perform a close rhetorical analysis of incidents in the television show Buffy the Vampire Slayer (Buffy) where female characters are violated physically, psychologically, and/or sexually. Buffy is one of the most-analyzed television shows of all time, with a particular emphasis on the show’s engagement with feminism; however, the issue of violation has received little scholarly investigation despite multiple instances of it within the show. Through examining the rhetorical elements (such as dialogue, camerawork, body language, and character response) that surround incidents of violation, this research reveals that Buffy …
Bodies Of Knowledge: The Accuracy Of Medical Anatomical Drawings From The 14th To The 18th Century, Marina G. Mitchell
Bodies Of Knowledge: The Accuracy Of Medical Anatomical Drawings From The 14th To The 18th Century, Marina G. Mitchell
Honors Undergraduate Theses
From the fourteenth to the eighteenth centuries, European anatomical illustration underwent major transformations in response to changing scientific methods, technologies, and visual conventions, reflecting critical transitions in anatomical history. Scientific evolution allowed these images to achieve increasing structural precision and internal detail, though they frequently diverged from anatomical forms as they are understood today. This study examines how anatomical inaccuracies across five centuries emerged not from ignorance, but from deliberate mediation between purpose, observation, pedagogy, artistic convention, and cultural ideology. Through close analysis of works in visual comparison to their modern counterparts, this thesis identifies specific deviations from the twenty-first …
Social Determinants Of Health Affecting Cardiovascular Health Among South Asian Americans, Ann Mary Thomas
Social Determinants Of Health Affecting Cardiovascular Health Among South Asian Americans, Ann Mary Thomas
Honors Undergraduate Theses
Background: South Asian Americans experience disproportionately high rates of cardiovascular disease, yet the social determinants contributing to these disparities remain understudied.
Objective: This systematic review examines the role of social determinants of health (SDOH) in shaping cardiovascular outcomes among South Asian Americans.
Methods: A systematic literature search was conducted across PubMed, MEDLINE, and Web of Science using predefined search terms related to South Asian populations, cardiovascular health, and SDOH. The review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 reporting guidelines, and study screening and management were performed using Covidence. A total …
Impact Of Senescence On Breast Cancer Outcomes, Gracie Sous
Impact Of Senescence On Breast Cancer Outcomes, Gracie Sous
Honors Undergraduate Theses
Cellular senescence is a biological process in which damaged cells exit the cell cycle while remaining metabolically active and accumulating within tissues. Senescence plays a complex role in breast cancer progression, largely through the secretion of senescence-associated secretory phenotype (SASP) factors. These factors include a broad range of inflammatory cytokines, chemokines, and signaling molecules that can influence the tumor microenvironment.
Studies suggest that senescence may significantly promote cancer metastasis. Therefore, this study aims to investigate the genes involved in cancer progression and to improve understanding of how SASP is regulated, which is critical for improving breast cancer outcomes. The central …
Feasibility Of Telehealth-Delivered Gut-Directed Hypnotherapy For Managing Gastrointestinal Health: Exploring Specific Vs. Nonspecific Effects, Sabrina Romero
Feasibility Of Telehealth-Delivered Gut-Directed Hypnotherapy For Managing Gastrointestinal Health: Exploring Specific Vs. Nonspecific Effects, Sabrina Romero
Honors Undergraduate Theses
This randomized controlled trial evaluated the feasibility and efficacy of telehealth-delivered Gut-Directed Hypnotherapy (GDH) compared to General Hypnotherapy (GH) for managing gastrointestinal symptoms associated with disorders of gut–brain interaction (DGBI). Eleven adults were randomized to receive four 1-hour hypnotherapy sessions over a 14-day period via Zoom (GH n = 5; GDH n = 6). Primary outcomes included PROMIS GI Belly Pain T-scores and Abdominal Pain Ratings assessed at baseline and post-treatment. Follow-up assessments were conducted at three months (n = 8). At post-treatment, participants receiving GDH demonstrated significantly lower PROMIS GI Belly Pain T-scores compared to GH, F(1, …
Investigating The Interaction Of Gram-Positive Lactobacillus Species With Mucin In The Context Of Barrett's Esophagus, Ritisha Suresh
Investigating The Interaction Of Gram-Positive Lactobacillus Species With Mucin In The Context Of Barrett's Esophagus, Ritisha Suresh
Honors Undergraduate Theses
Gastroesophageal Reflux Disease (GERD) can progress to the precancerous Barrett’s Esophagus (BE) condition, in which the normal esophageal squamous epithelium is replaced with a columnar epithelium containing goblet cells. Mucins, sticky substances, are secreted in response to bile acid exposure during reflux episodes to protect the esophageal epithelium. Goblet cells secrete these mucins, which can also scaffold microbial colonization. Probiotic Lactobacillus bacteria can use glycosidase enzymes to process mucin and metabolize them into their component sugars (glycans). This project aims to identify the role of the Lactobacillus-mucin interaction in BE, as glycan availability could confer an advantage to Lactobacillus …
The Relationships Among Adverse Childhood Experiences, Medical Usage, And Somatic Symptoms: Stress And Coping As Mediating Factors, Samantha Harper
The Relationships Among Adverse Childhood Experiences, Medical Usage, And Somatic Symptoms: Stress And Coping As Mediating Factors, Samantha Harper
Honors Undergraduate Theses
It has been estimated that the costs of childhood adversity amount to $14.1 trillion annually (Peterson et al., 2023). Nearly two-thirds of people report adverse childhood experiences (ACEs), including abuse, neglect, or household dysfunction, that reverberate well beyond childhood (Centers for Disease Control and Prevention [CDC], 2023; Felitti et al., 1998). Greater exposure to ACEs is linked consistently to poorer health outcomes, including somatic symptoms or physical symptoms with no organic cause (Katon & Walker, 1998; Sansone et al., 2001; Stuart & Noyes, 1999; Waldinger, 2006). The present study examined the relationships among ACEs, somatic symptoms, and healthcare utilization in …
Impact Of Prostate Cancer Tumor Microenvironment On Alternative Splicing Landscapes In Nk Cells: An Lncap-Based In Vitro Model, Pratham N. Modi
Impact Of Prostate Cancer Tumor Microenvironment On Alternative Splicing Landscapes In Nk Cells: An Lncap-Based In Vitro Model, Pratham N. Modi
Honors Undergraduate Theses
NK cells play a significant role in anti-tumor activity, yet the transcriptomic mechanisms underlying NK cell dysfunction in the prostate cancer tumor microenvironment remain generally poorly characterized. While most transcriptomic studies focus on gene-level expression, alternative splicing and isoform-level analysis may reveal additional levels of regulation not identified in traditional analysis. The overall goal of this study was to characterize gene and isoform-level changes in NK cells exposed to in vitro prostate cancer conditions and to evaluate whether isoform-level analysis could provide additional depth and insights beyond gene-level analyses. NK92-MI cells were co-cultured with LNCaP prostate cancer cells using direct-contact …
Illuminating Those Who Lurk In The Shadows: An Examination Of The Use Of Psychological Profiling In Identifying Violent Criminals In The Modern Age, Skylar R. Holmes
Illuminating Those Who Lurk In The Shadows: An Examination Of The Use Of Psychological Profiling In Identifying Violent Criminals In The Modern Age, Skylar R. Holmes
Honors Undergraduate Theses
This study examines the role of psychological profiling in apprehending violent criminals. Psychological profiling involves analyzing behavioral patterns at crime scenes, exploring the relationships between victims, and identifying characteristics and tendencies of offenders. It is currently used by many law enforcement agencies across the country to narrow down a pool of potential suspects and direct researchers, making the most of the limited manpower available. There is, however, a significant limitation in the literature and available evidence that suggests its tenets may be based on intuition and anecdotal evidence purported by investigators, subject to internal bias and thus should not be …
Regulation Of The Low-Density Lipoprotein Receptor In A Colon Cancer Cell Line By The Prostasin Serine Protease, Juan Pablo Ruiz
Regulation Of The Low-Density Lipoprotein Receptor In A Colon Cancer Cell Line By The Prostasin Serine Protease, Juan Pablo Ruiz
Honors Undergraduate Theses
In the effort to combat hypercholesterolemia and cardiovascular disease, research has turned to studying the effects of serine proteases on the low-density lipoprotein receptor (LDLR), which plays a key role in the diseased states with high LDL levels. Matriptase has been shown to proteolytically shed the extracellular domain (ECD) of the LDLR in the co-translational setting. Prostasin (PRSS8) and matriptase (ST14) are part of a proteolytic activation cascade and it is hypothesized that the coactivation of prostasin and matriptase or a pharmacological perturbation of the steady state could result in LDLR ECD shedding in cells co-expressing the receptor and the …
Comparative Spatial Biology: A Cross-Species Analysis Of Canine Oral Cancers As Models For Human Disease, Ram Pradhyumnan
Comparative Spatial Biology: A Cross-Species Analysis Of Canine Oral Cancers As Models For Human Disease, Ram Pradhyumnan
Honors Undergraduate Theses
Oral squamous cell carcinoma (OSCC), one of the most common malignancies of the oral cavity, remains a clinically challenging disease due to its aggressive behavior, late-stage diagnosis, and limited improvements in therapeutic outcomes over recent decades. A significant barrier to progress in OSCC research and treatment is the lack of suitable preclinical models that recapitulate the complexity and natural progression of the disease. Most current models—including cell lines, xenografts, and genetically engineered mice—fail to capture key features such as the spatial organization of tumor epithelium, interactions with an intact immune system, and the stepwise evolution from normal mucosa to invasive …
Who Makes The Jury? Demographics And Decision-Making In The Jury Process., Ana B. Pons
Who Makes The Jury? Demographics And Decision-Making In The Jury Process., Ana B. Pons
Honors Undergraduate Theses
Within the American judicial system, juries have played a central role in promoting representation and fairness in the courtroom. However, limited information exists on whether prosecutorial decisions during jury selection, jury composition, or jury behavior differ based on the sex, race/ethnicity, type of case, political ideology, or geographic location of potential jurors. Following PRISMA guidelines, this scoping review synthesizes 48 peer-reviewed articles published between the 1940s and 2026 to examine whether prosecutorial decision-making and jury outcomes vary based on the sex, race/ethnicity, type of case, political ideology, or geographic location of potential jurors. Findings indicated that men are disproportionately selected …