Digital Commons Network^™

The Depuration Of Microplastic Pollution In Aquacultured Indian River Lagoon Oysters, Lee Nguyen

Honors Undergraduate Theses

Plastics are widely used in consumer goods and industrial manufacturing, and their degradation into microplastics (MP, size < 5 mm) has created an emergent environmental pollutant. Plastics readily enter aquatic environments, where they accumulate additional contaminants and bioaccumulate in organisms. While MP contamination in marine ecosystems is well documented, less is known about MP presence in aquacultured shellfish. Depuration, the process of purging contaminants from shellfish, is conducted in sterile seawater without food, which may cause oyster starvation and death. To date, MP depuration has not been examined in the aquacultured eastern oyster (Crassostrea virginica) in published studies. This study had 3 goals: 1) evaluate the effects of algal feed on oyster survival during depuration, 2) determine the effect of algal feed on depuration effectiveness, and 3) investigate the effect of a ten-day depuration on MP concentration in aquacultured C. virginica soft tissue. MP were quantified in oyster tissues, biodeposits, and in industrial algal feed. Tissues were digested using alkaline solutions, manually examined via microscopy, and analyzed using Fourier-Transform Infrared Spectroscopy (FTIR) to investigate MP polymer …

The Impact Of Gastric Sleeve And Roux-En-Y Gastric Bypass On Chief Cell Function And Protein Digestion In Obese Patients, Garikoitz Mikel Gainza

Honors Undergraduate Theses

Obesity has become one of the largest global health concerns of the 21^st century, correlating with numerous associated diseases. To help address the growing prevalence and burden of obesity, sleeve gastrectomy and Roux-en-Y gastric bypass have become two commonly performed surgical procedures done to promote weight loss by altering the anatomical structure of the stomach and surrounding organs of the gastrointestinal system. Although the benefits of improved metabolism linked to these surgical procedures are well studied, their impact on the physiology of gastric cells, and more specifically chief cells as they relate to protein digestion post-surgery, is yet to …

Examining The Results Of Revolutions In The Third World: A Case Study Of The Iranian, Libyan, And Nicaraguan Revolutions, Noah A. Mohammedelamien

Honors Undergraduate Theses

This thesis examines the post-revolutionary trajectories of Libya, Iran, and Nicaragua to explain why some Third World revolutionary projects preserve and use elements of their founding ideology while others fragment, personalize, or diffuse over time. Rather than focusing on the causes of revolution alone, it analyzes the durability of religious-socialist ideological continuity after revolutionary upheaval. Using a (MDSD) comparative historical and institutional approach grounded in primary and secondary sources, the study evaluates five key dimensions across the cases: religious-socialist ideological fusion, religious elite loyalty, popular religious mobilization, institutional embedding of ideology, and external pressure. The findings suggest ideological continuity is …

Noninvasive Monitoring Techniques: The Use Of Scat-Sourced Dna And Camera Traps To Monitor Mammalian Carnivore Species At The Ucf Arboretum, Zachary Montealegre

Honors Undergraduate Theses

The 800-acre University of Central Florida Arboretum Natural Lands functions as a conservation area, recreational space, and research site, making it essential to understand the ecological community it supports. Traditional wildlife monitoring methods such as mark-recapture and blood sampling can be effective but may stress animals or disrupt natural behaviors. To minimize these impacts, this study used non-invasive techniques, specifically scat-based DNA analysis and camera trapping, to assess carnivore species' presence. Two ecologically similar sites within the Arboretum were selected. Suspected carnivore scat was collected twice weekly over two months using both structured and opportunistic sampling. DNA was extracted, amplified, …

Associations Between Oral Hormonal Contraceptive Use, Digestive And Other Health Symptoms In Young Women, Silviana E. Buzatu

Honors Undergraduate Theses

Oral hormonal contraceptives (OHCs) are widely used among reproductive-age women; however, their gastrointestinal (GI) side effects remain understudied. The present study examined associations between OHC use, GI, physical, and psychological symptom burden in a large sample of undergraduate women. Participants (N = 669) aged 18 to 25 years were recruited from UCF’s SONA system and classified into three groups based on self-reported contraceptive status: no birth control, combined estrogen–progestin OHC, and progestin-only OHC. Participants completed GI questionnaires, as well as physical and mental health symptoms ones.

Multivariate analyses indicated that overall GI symptom profiles did not differ significantly by birth …

Repurposing Cyclin-Dependent Kinase Inhibitors For The Discovery Of Novel Antiplasmodial Compounds, Ritam Bhowmik

Honors Undergraduate Theses

Malaria remains a major global health burden with over 282 million cases annually and rising resistance to artemisinin-based combination therapies. Plasmodium falciparum, the most lethal malaria parasite species in humans, relies on tightly regulated cell cycle progression during replication within red blood cells. Cyclin-dependent kinases (CDKs) are central regulators of eukaryotic cell division and transcription, and several CDK-like enzymes in P. falciparum, including Pfmrk and PfPK6, are essential for parasite growth and structurally distinct from human kinases. This study evaluated whether commercially available human CDK inhibitors (CDKIs) targeting cancer pathways could be repurposed as novel antimalarial compounds. A library of …

Manuka Honey Modulates Oxidative Stress In Neuro2-A Cells Through Mitochondrial Regulation, Rachel Abramovici

Honors Undergraduate Theses

Manuka honey is known for its vital usage in wound healing, being an agonist towards fighting infections, and is an acting antioxidant [32]. Its main constituents are flavonoids and phenolic compounds, with methyl syringate (MSYR) being a major active ingredient. The specific compounds responsible for these antioxidant effects, particularly in the CNS, remain unclear. It is hypothesized that pre-treatment of mouse neuroblastoma cells with MSYR followed by hydrogen peroxide exposure will activate the AMPK/SIRT1/PGC-1a pathway, due to MSYR’s phenolic structure, and thus reduce oxidative stress and improve mitochondrial biogenesis. Hydrogen peroxide is a standard reactive oxygen species (ROS) treatment to …

Transforming Florida Chemistry Education: Exploring Information Literacy Strategies From Singapore, Han N. Le

Honors Undergraduate Theses

This study explores the applicability of Singapore’s information literacy (IL) strategies within Central Floridian higher education environments. Singapore’s national IL framework, supported by its Ministry of Education, integrates information and communication technology (ICT), professional development, and lifelong learning initiatives through a standardized, systemwide approach. In contrast, IL instruction in the United States is largely decentralized, often limited to one-time sessions or elective courses. To investigate the feasibility of adapting Singapore’s practices, surveys were distributed to faculty and librarians across Florida’s twelve public universities, yielding responses that highlighted varying levels of IL integration, limited institutional support, and minimal professional training related …

Multicomponent Deoxyribozyme Probes For Targeted Detection Of Cancer Associated Gene Insertions, Samuel R. Veleke

Honors Undergraduate Theses

Insertions and deletions (indels) in DNA sequences of genes are linked with cancers such as glioblastoma (GB). Thus, indels may be used as potential cancer biomarkers. In the NANOG gene, its pseudogene NANOGP8 has a 22 base pair insertion sequence for GB patients. In this work, the NANOG gene and the insertion sequence were detected in one sample using a dual-fluorescent assay containing two multicomponent split deoxyribozyme (Dz) probe complexes. One complex used TXR fluorescence to detect the gene regardless of the insertion’s presence. The other complex used fluorescein (FAM) fluorophore to detect the insertion. The probes were able to …

Slay Her: The Rhetoric Of Violation In Buffy The Vampire Slayer, Lea N. Wright

Honors Undergraduate Theses

This research draws on feminist theory and monster theory to perform a close rhetorical analysis of incidents in the television show Buffy the Vampire Slayer (Buffy) where female characters are violated physically, psychologically, and/or sexually. Buffy is one of the most-analyzed television shows of all time, with a particular emphasis on the show’s engagement with feminism; however, the issue of violation has received little scholarly investigation despite multiple instances of it within the show. Through examining the rhetorical elements (such as dialogue, camerawork, body language, and character response) that surround incidents of violation, this research reveals that Buffy …

Bodies Of Knowledge: The Accuracy Of Medical Anatomical Drawings From The 14th To The 18th Century, Marina G. Mitchell

Honors Undergraduate Theses

From the fourteenth to the eighteenth centuries, European anatomical illustration underwent major transformations in response to changing scientific methods, technologies, and visual conventions, reflecting critical transitions in anatomical history. Scientific evolution allowed these images to achieve increasing structural precision and internal detail, though they frequently diverged from anatomical forms as they are understood today. This study examines how anatomical inaccuracies across five centuries emerged not from ignorance, but from deliberate mediation between purpose, observation, pedagogy, artistic convention, and cultural ideology. Through close analysis of works in visual comparison to their modern counterparts, this thesis identifies specific deviations from the twenty-first …

Social Determinants Of Health Affecting Cardiovascular Health Among South Asian Americans, Ann Mary Thomas

Honors Undergraduate Theses

Background: South Asian Americans experience disproportionately high rates of cardiovascular disease, yet the social determinants contributing to these disparities remain understudied.

Objective: This systematic review examines the role of social determinants of health (SDOH) in shaping cardiovascular outcomes among South Asian Americans.

Methods: A systematic literature search was conducted across PubMed, MEDLINE, and Web of Science using predefined search terms related to South Asian populations, cardiovascular health, and SDOH. The review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 reporting guidelines, and study screening and management were performed using Covidence. A total …

Impact Of Senescence On Breast Cancer Outcomes, Gracie Sous

Honors Undergraduate Theses

Cellular senescence is a biological process in which damaged cells exit the cell cycle while remaining metabolically active and accumulating within tissues. Senescence plays a complex role in breast cancer progression, largely through the secretion of senescence-associated secretory phenotype (SASP) factors. These factors include a broad range of inflammatory cytokines, chemokines, and signaling molecules that can influence the tumor microenvironment.

Studies suggest that senescence may significantly promote cancer metastasis. Therefore, this study aims to investigate the genes involved in cancer progression and to improve understanding of how SASP is regulated, which is critical for improving breast cancer outcomes. The central …

Feasibility Of Telehealth-Delivered Gut-Directed Hypnotherapy For Managing Gastrointestinal Health: Exploring Specific Vs. Nonspecific Effects, Sabrina Romero

Honors Undergraduate Theses

This randomized controlled trial evaluated the feasibility and efficacy of telehealth-delivered Gut-Directed Hypnotherapy (GDH) compared to General Hypnotherapy (GH) for managing gastrointestinal symptoms associated with disorders of gut–brain interaction (DGBI). Eleven adults were randomized to receive four 1-hour hypnotherapy sessions over a 14-day period via Zoom (GH n = 5; GDH n = 6). Primary outcomes included PROMIS GI Belly Pain T-scores and Abdominal Pain Ratings assessed at baseline and post-treatment. Follow-up assessments were conducted at three months (n = 8). At post-treatment, participants receiving GDH demonstrated significantly lower PROMIS GI Belly Pain T-scores compared to GH, F(1, …

Investigating The Interaction Of Gram-Positive Lactobacillus Species With Mucin In The Context Of Barrett's Esophagus, Ritisha Suresh

Honors Undergraduate Theses

Gastroesophageal Reflux Disease (GERD) can progress to the precancerous Barrett’s Esophagus (BE) condition, in which the normal esophageal squamous epithelium is replaced with a columnar epithelium containing goblet cells. Mucins, sticky substances, are secreted in response to bile acid exposure during reflux episodes to protect the esophageal epithelium. Goblet cells secrete these mucins, which can also scaffold microbial colonization. Probiotic Lactobacillus bacteria can use glycosidase enzymes to process mucin and metabolize them into their component sugars (glycans). This project aims to identify the role of the Lactobacillus-mucin interaction in BE, as glycan availability could confer an advantage to Lactobacillus …

The Relationships Among Adverse Childhood Experiences, Medical Usage, And Somatic Symptoms: Stress And Coping As Mediating Factors, Samantha Harper

Honors Undergraduate Theses

It has been estimated that the costs of childhood adversity amount to $14.1 trillion annually (Peterson et al., 2023). Nearly two-thirds of people report adverse childhood experiences (ACEs), including abuse, neglect, or household dysfunction, that reverberate well beyond childhood (Centers for Disease Control and Prevention [CDC], 2023; Felitti et al., 1998). Greater exposure to ACEs is linked consistently to poorer health outcomes, including somatic symptoms or physical symptoms with no organic cause (Katon & Walker, 1998; Sansone et al., 2001; Stuart & Noyes, 1999; Waldinger, 2006). The present study examined the relationships among ACEs, somatic symptoms, and healthcare utilization in …

Regulation Of The Low-Density Lipoprotein Receptor In A Colon Cancer Cell Line By The Prostasin Serine Protease, Juan Pablo Ruiz

Honors Undergraduate Theses

In the effort to combat hypercholesterolemia and cardiovascular disease, research has turned to studying the effects of serine proteases on the low-density lipoprotein receptor (LDLR), which plays a key role in the diseased states with high LDL levels. Matriptase has been shown to proteolytically shed the extracellular domain (ECD) of the LDLR in the co-translational setting. Prostasin (PRSS8) and matriptase (ST14) are part of a proteolytic activation cascade and it is hypothesized that the coactivation of prostasin and matriptase or a pharmacological perturbation of the steady state could result in LDLR ECD shedding in cells co-expressing the receptor and the …

Comparative Spatial Biology: A Cross-Species Analysis Of Canine Oral Cancers As Models For Human Disease, Ram Pradhyumnan

Honors Undergraduate Theses

Oral squamous cell carcinoma (OSCC), one of the most common malignancies of the oral cavity, remains a clinically challenging disease due to its aggressive behavior, late-stage diagnosis, and limited improvements in therapeutic outcomes over recent decades. A significant barrier to progress in OSCC research and treatment is the lack of suitable preclinical models that recapitulate the complexity and natural progression of the disease. Most current models—including cell lines, xenografts, and genetically engineered mice—fail to capture key features such as the spatial organization of tumor epithelium, interactions with an intact immune system, and the stepwise evolution from normal mucosa to invasive …

Who Makes The Jury? Demographics And Decision-Making In The Jury Process., Ana B. Pons

Honors Undergraduate Theses

Within the American judicial system, juries have played a central role in promoting representation and fairness in the courtroom. However, limited information exists on whether prosecutorial decisions during jury selection, jury composition, or jury behavior differ based on the sex, race/ethnicity, type of case, political ideology, or geographic location of potential jurors. Following PRISMA guidelines, this scoping review synthesizes 48 peer-reviewed articles published between the 1940s and 2026 to examine whether prosecutorial decision-making and jury outcomes vary based on the sex, race/ethnicity, type of case, political ideology, or geographic location of potential jurors. Findings indicated that men are disproportionately selected …

Invasion Of Microplastics Into The Reproductive Tissues Of Feral And Domestic Felines, Emma K. Quade

Honors Undergraduate Theses

Although plastics have many useful properties in modern society, once these materials are introduced into the environment, they can cause extensive damage. Following degradation into microplastics (MP), plastic particles less than 5 mm in size, these contaminants can make their way into a variety of different environments and organisms. There are many studies that have investigated the prevalence of MP in marine environments, but fewer studies have looked into terrestrial systems, and even less that have focused on contamination in companion animals. This study sought to investigate the invasion of MP into the reproductive tissues of felines, Felis catus, …

Interaction Of The Dap-10 Fluorescent Light-Up Aptamer With An Environment-Sensitive Dye, Crystal Violet, Marina Tsukanova

Honors Undergraduate Theses

Crystal violet (CV) is an environment-sensitive dye whose fluorescence is strongly influenced by microenvironment polarity and viscosity, increasing markedly when rotational and vibrational motions are restricted. While the fluorescence enhancement of CV by fluorescent light-up aptamers (FLAPs) has been noted in literature, the specific binding interactions between CV and aptamers in the DAP-10 family have remained under-investigated.  The objective of this work is to elucidate the binding site interactions between CV and the DAP-10-42 FLAP. It is hypothesized that positions 34 and 35 of the aptamer’s sequence reside in a proposed quadruplex-duplex junction that form the dye-binding pocket of DAP-10 …

How Does The Frequency Of Visits Impact The Quality Of Life For Nursing Home Residents?, Sophie M. Carlton

Honors Undergraduate Theses

This integrative literature review examines the relationship between quantity of visitation and quality of life (QOL) of nursing home residents. The purpose of this review is to examine existing research to determine whether an optimal “dosage” of visitation exists that meaningfully enhances QOL for this vulnerable population. Establishing an evidence based- guideline may help reduce uncertainty for families and promote more consistent improvements in resident well-being. Nursing home residents are the focus of this work because their limited ability to leave the facility makes visitation one of their primary sources of non-occupational social interaction. The COVID19 pandemic further heightened the …

Analyzing Early Medieval Perspectives Of Fetal Development, Nivedha Srinivasan

Honors Undergraduate Theses

This thesis examines early medieval perspectives of fetal development by analyzing two manuscripts: British Library, Cotton Tiberius A III and Leiden University, Vossianus lat. Q69. This study will investigate how knowledge of pregnancy was shared throughout England before the establishment of universities. Interest in medieval reproductive language has piqued in importance in recent years, especially due to modern legal debates surrounding reproductive rights. By examining descriptions of the nine months of fetal development in these two manuscripts, as well as in widely known earlier medical texts like Pliny’s Natural History and Vindicianus’ Gynaecia, this research explores how monastic writers in …

Barriers To Mental Health Care Among Emerging Adult Women Across Racial, Ethnic, And Lgbtq+ Identities, Tikyla M. Euline

Honors Undergraduate Theses

Emerging adulthood is a developmental period characterized by increasing mental health concerns, yet many young adults do not seek professional psychological services. The present study examined barriers to mental health care among undergraduate women, with particular attention to the intersecting identities of sexual minority status and racial/ethnic minority status. Guided by intersectionality theory, the study investigated whether LGBTQ+ women, women of color, and individuals holding both identities reported greater perceived barriers to treatment, higher levels of medical mistrust and discrimination in healthcare settings, and lower mental health service utilization. Participants included 373 undergraduate women between the ages of 18 and …

Generating Genomic Resources For The Pink Sundew And Its Specialist Herbivore Moth From A Single Gene To Entire Genomes, Kerissa F. Tarpley

Honors Undergraduate Theses

Genomic resources are critical for the conservation of threatened species, providing valuable insights into genetic diversity, population structure, and adaptive potential. This thesis focuses on two ecologically interconnected species: the carnivorous plant pink sundew (Drosera capillaris) and its specialist herbivore the sundew plume moth (Buckleria parvulus). The sundew and plume moth face an uncertain future as their vital bog habitats continue to disappear. The sundew plays a crucial role in the life cycle of the plume moth, which relies on the sundew during its larval stages for survival. To aid in species detections, I first generated …

Assessing The Impact Of Storing Water Samples At Ambient Temperature On Plankton Metabarcoding, Stephanie N. Lievano

Honors Undergraduate Theses

Increasing incidence of Harmful Algal Blooms (HABs) has led to fish kills, air quality hazards, and economic impacts. One economic impact is on tourism, one of the main sources of Florida’s income, where billions of dollars are lost to such events. The Florida Fish and Wildlife Conservation Commission Fish and Wildlife Research Institute (FWC-FWRI), with the help of collaborators, collects water samples from across the state for HAB monitoring. These samples are stored at ambient temperature for up to 24 hours which could directly affect data analyses. Here, in collaboration with FWRI-FWC, I investigated whether this storage technique affects plankton …

Switching Languages, Switching Personalities: The Socio-Cognitive Implications Of Bilingualism, Hannah F. Stern

Honors Undergraduate Theses

The increasing prevalence of bilingualism worldwide highlights the importance of further research into its impact on socio-cognitive processes. This study examines variations in personality traits, anxiety levels, locus of control, and cognitive load during language switching, utilizing cultural and visual-linguistic priming techniques to explore real-time socio-cognitive shifts across language contexts. A 2×3 mixed-factorial design compared language groups (monolingual vs. bilingual) across three priming conditions (semantic, cultural, and control). 120 participants completed a series of subjective and objective measures, including the Big Five Personality Inventory, Liebowitz Social Anxiety Scale, and Rotter’s I-E Scale in both languages, with controlled language-specific priming conditions …

Individual Differences In Personality Traits And Anthropomorphic Tendencies, Olivia S. Young

Honors Undergraduate Theses

Anthropomorphism is broadly defined as the attribution of human characteristics to nonhuman entities. Those with higher levels of neurodivergent traits, such as autism spectrum disorder (ASD), may struggle to maintain eye contact with and interpret the emotions of others. Anthropomorphic interaction patterns between both those with and without ASD differ between various entities such as cars, cartoon characters, animals, and humans. Results of this study have implications across domains including human factors, cognitive science, and human-animal interaction. This study employed the use of unique stimuli in combination with various scales to measure personality traits and anthropomorphic tendencies. Participants were asked …

The Implicit Perceptions Of Asian American Adoptees And Their Clinical Implications, Cai Li L. Franckewich

Honors Undergraduate Theses

Asian American adoptees occupy a unique “in-between” space, shaped by societal perceptions of race, culture, and family context. This study examined how family composition and racial pairings influence perceptions of an Asian American adoptee. Undergraduate students completed an online survey in which they were randomly shown one of five images depicting the adoptee with different family compositions, without being told she was adopted. Participants then read a story describing the adoptee experiencing common college stressors, and rated statements on a 7-point Likert scale regarding the adoptee’s well-being, factors influencing her behavior, and behavioral descriptors. Results indicated that participants perceived stronger …

The Psychological Effect Of Maternal Separation From A Child During Incarceration: A Survey And Critique Of Risk Needs Assessments, Samantha Yearwood

Honors Undergraduate Theses

This study examines whether frequently used correctional assessment instruments adequately capture the psychological impacts of maternal-child separation among incarcerated women. This research was conducted in response to growing criticisms that traditional risk and needs assessments fail to account for gender-specific experiences, specifically those related to caregiving roles and pregnancy. Using a qualitative analysis content analysis to assess four widely used instruments, the Women’s Risk and Needs Assessment (WRNA), Correctional Offender Management Profiling for Alternative Sanctions (COMPAS), Brief Symptom Inventory-18 (BSI-18), and Level of Service Inventory–Revised (LSI-R), the thesis  examines the inclusion of pregnancy-related variables, caregiving responsibilities, and separation-related psychological factors. …