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Gene Expression Of Key Regulators Of Mitochondrial Biogenesis Is Sex Dependent In Mice With Growth Hormone Receptor Deletion In Liver, Ilona Zawada, Michal M. Masternak, Edward O. List, Michael B. Stout, Darlene E. Berryman, Andrzej Lewinski, John J. Kopchick, Andrzej Bartke, Malgorzata Karbownik-Lewinska Jan 2015

Gene Expression Of Key Regulators Of Mitochondrial Biogenesis Is Sex Dependent In Mice With Growth Hormone Receptor Deletion In Liver, Ilona Zawada, Michal M. Masternak, Edward O. List, Michael B. Stout, Darlene E. Berryman, Andrzej Lewinski, John J. Kopchick, Andrzej Bartke, Malgorzata Karbownik-Lewinska

Faculty Bibliography 2010s

Mitochondrial biogenesis is an essential process for cell viability. Mice with disruption of the growth hormone receptor (GHR) gene (Ghr gene) in the liver (LiGHRKO), in contrast to long-lived mice with global deletion of the Ghr gene (GHRKO), are characterized by lack of improved insulin sensitivity and severe hepatic steatosis. Tissue-specific disruption of the GHR in liver results in a mouse model with dramatically altered GH/IGF1 axis. We have previously shown increased levels of key regulators of mitochondrial biogenesis in insulin-sensitive GHRKO mice. The aim of the present study is to assess, using real-time PCR, the gene expression of key …

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Counseling Multiple-Heritage Couples, Ashley J. Blount, Mark E. Young Jan 2015

Counseling Multiple-Heritage Couples, Ashley J. Blount, Mark E. Young

Faculty Bibliography 2010s

Multiple-heritage couples are one of the fastest growing client populations in the United States. These partnerships are defined by intersecting ethnic, racial, linguistic, and religious differences. They are challenged by societal perceptions, stereotypes, and other pressures associated with being in a multiple-heritage pairing. This article discusses strengths in the multiple-heritage union brought about by the understanding of diverse viewpoints. Finally, the article identifies specific strategies, such as couples relationship education, to resolve and confront inherent differences. Las parejas multiculturales son uno de los grupos demograficos de clientes de mayor crecimiento en los Estados Unidos. Este tipo de parejas se define …

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The Impact Of Demographic And Perceptual Variables On A Young Adult's Decision To Be Covered By Private Health Insurance, John Cantiello, Myron D. Fottler, Dawn Oetjen, Ning Jackie Zhang Jan 2015

The Impact Of Demographic And Perceptual Variables On A Young Adult's Decision To Be Covered By Private Health Insurance, John Cantiello, Myron D. Fottler, Dawn Oetjen, Ning Jackie Zhang

Faculty Bibliography 2010s

Background: The large number of uninsured individuals in the United States creates negative consequences for those who are uninsured and for those who are covered by health insurance plans. Young adults between the ages of 18 and 24 are the largest uninsured population subgroup. This subgroup warrants analysis. The major aim of this study is to determine why young adults between the ages of 18 and 24 are the largest uninsured population subgroup. Methods: The present study seeks to determine why young adults between the ages of 18 and 24 are the largest population subgroup that is not covered by …

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Tuning The Correlated Color Temperature Of White Led With A Guest-Host Liquid Crystal, Haiwei Chen, Zhenyue Luo, Ruidong Zhu, Qi Hong, Shin-Tson Wu Jan 2015

Tuning The Correlated Color Temperature Of White Led With A Guest-Host Liquid Crystal, Haiwei Chen, Zhenyue Luo, Ruidong Zhu, Qi Hong, Shin-Tson Wu

Faculty Bibliography 2010s

We demonstrate an electro-optic method to tune the correlated color temperature (CCT) of white light-emitting-diode (WLED) with a color conversion film, consisting of fluorescent dichroic dye doped in a liquid crystal host. By controlling the molecular reorientation of dichroic dyes, the power ratio of the transmitted blue and red lights of the white light can be accurately manipulated, resulting in different CCT. In a proof-of-concept experiment, we showed that the CCT of a yellow phosphor-converted WLED can be tuned from 3200 K to 4100 K. With further optimizations, the tuning range could be enlarged to 2500 K with fairly good …

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Role Of Neuronal Nadph Oxidase 1 In The Peri-Infarct Regions After Stroke, Dong-Hee Choi, Ji-Hye Kim, Kyoung-Hee Lee, Hahn-Young Kim, Yoon-Seong Kim, Wahn Soo Choi, Jongmin Lee Jan 2015

Role Of Neuronal Nadph Oxidase 1 In The Peri-Infarct Regions After Stroke, Dong-Hee Choi, Ji-Hye Kim, Kyoung-Hee Lee, Hahn-Young Kim, Yoon-Seong Kim, Wahn Soo Choi, Jongmin Lee

Faculty Bibliography 2010s

The molecular mechanism underlying the selective vulnerability of neurons to oxidative damage caused by ischemia-reperfusion (I/R) injury remains unknown. We sought to determine the role of NADPH oxidase 1 (Nox1) in cerebral I/R-induced brain injury and survival of newborn cells in the ischemic injured region. Male Wistar rats were subjected to 90 min middle cerebral artery occlusion (MCAO) followed by reperfusion. After reperfusion, infarction size, level of superoxide and 8-hydroxy-20-deoxyguanosine (8-oxo-2dG), and Nox1 immunoreactivity were determined. RNAi-mediated knockdown of Nox1 was used to investigate the role of Nox1 in I/R-induced oxidative damage, neuronal death, motor function recovery, and ischemic neurogenesis. …

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The Stroke Hyperglycemia Insulin Network Effort (Shine) Trial: An Adaptive Trial Design Case Study, Jason T. Connor, Kristine R. Broglio, Valerie Durkalski, William J. Meurer, Karen C. Johnston Jan 2015

The Stroke Hyperglycemia Insulin Network Effort (Shine) Trial: An Adaptive Trial Design Case Study, Jason T. Connor, Kristine R. Broglio, Valerie Durkalski, William J. Meurer, Karen C. Johnston

Faculty Bibliography 2010s

Background: The 'Adaptive Designs Accelerating Promising Trials into Treatments (ADAPT-IT)' project is a collaborative effort supported by the National Institutes of Health (NIH) and United States Food & Drug Administration (FDA) to explore how adaptive clinical trial design might improve the evaluation of drugs and medical devices. ADAPT-IT uses the National Institute of Neurologic Disorders & Stroke-supported Neurological Emergencies Treatment Trials (NETT) network as a 'laboratory' in which to study the development of adaptive clinical trial designs in the confirmatory setting. The Stroke Hyperglycemia Insulin Network Effort (SHINE) trial was selected for funding by the NIH-NINDS at the start of …

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Thyroxine Modifies The Effects Of Growth Hormone In Ames Dwarf Mice, Andrew Do, Vinal Menon, Xu Zhi, Adam Gesing, Denise S. Wiesebborn, Adam Spong, Liou Sun, Andrzej Bartke, Michal M. Masternak Jan 2015

Thyroxine Modifies The Effects Of Growth Hormone In Ames Dwarf Mice, Andrew Do, Vinal Menon, Xu Zhi, Adam Gesing, Denise S. Wiesebborn, Adam Spong, Liou Sun, Andrzej Bartke, Michal M. Masternak

Faculty Bibliography 2010s

Ames dwarf (df/df) mice lack growth hormone (GH), thyroid stimulating hormone and prolactin. Treatment of juvenile df/df mice with GH alone stimulates somatic growth, reduces insulin sensitivity and shortens lifespan. Early-life treatment with thyroxine (T4) alone produces modest growth stimulation but does not affect longevity. In this study, we examined the effects of treatment of juvenile Ames dwarf mice with a combination of GH + T4 and compared them to the effects of GH alone. Treatment of female and male dwarfs with GH + T4 between the ages of 2 and 8 weeks rescued somatic growth yet did not reduce …

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Mcp-Induced Protein 1 Mediates The Minocycline-Induced Neuroprotection Against Cerebral Ischemia/Reperfusion Injury In Vitro And In Vivo, Zhuqing Jin, Jian Liang, Jing Wang, Pappachan Kolattukudy Jan 2015

Mcp-Induced Protein 1 Mediates The Minocycline-Induced Neuroprotection Against Cerebral Ischemia/Reperfusion Injury In Vitro And In Vivo, Zhuqing Jin, Jian Liang, Jing Wang, Pappachan Kolattukudy

Faculty Bibliography 2010s

Background: Minocycline, a broad-spectrum tetracycline antibiotic, has shown anti-inflammatory and neuroprotective effects in ischemic brain injury. The present study seeks to determine whether monocyte chemotactic protein-induced protein 1 (MCPIP1), a recently identified modulator of inflammatory reactions, is involved in the cerebral neuroprotection conferred by minocycline treatment in the animal model of focal cerebral ischemia and to elucidate the mechanisms of minocycline-induced ischemic brain tolerance. Methods: Focal cerebral ischemia was induced by middle cerebral artery occlusion (MCAO) for 2 h in male C57BL/6 mice and MCPIP1 knockout mice followed by 24-or 48-h reperfusion. Twelve hours before ischemia or 2 h after …

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Modeling Undetected Live Poliovirus Circulation After Apparent Interruption Of Transmission: Implications For Surveillance And Vaccination, Dominika A. Kalkowska, Radboud J. Duintjer Tebbens, Mark A. Pallanscha, Stephen L. Cochi, Steven G. F. Wassilak, Kimberly M. Thompson Jan 2015

Modeling Undetected Live Poliovirus Circulation After Apparent Interruption Of Transmission: Implications For Surveillance And Vaccination, Dominika A. Kalkowska, Radboud J. Duintjer Tebbens, Mark A. Pallanscha, Stephen L. Cochi, Steven G. F. Wassilak, Kimberly M. Thompson

Faculty Bibliography 2010s

Background: Most poliovirus infections occur with no symptoms and this leads to the possibility of silent circulation, which complicates the confirmation of global goals to permanently end poliovirus transmission. Previous simple models based on hypothetical populations assumed perfect detection of symptomatic cases and suggested the need to observe no paralytic cases from wild polioviruses (WPVs) for approximately 3-4 years to achieve 95% confidence about eradication, but the complexities in real populations and the imperfect nature of surveillance require consideration. Methods: We revisit the probability of undetected poliovirus circulation using a more comprehensive model that reflects the conditions in a number …

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Resolution Of Crohn's Disease And Complex Regional Pain Syndrome Following Treatment Of Paratuberculosis, J. Todd Kuenstner, William Chamberlin, Saleh A. Naser, Michael T. Collins, Coad Thomas Dow, John M. Aitken, Stuart Weg, Grzegorz Telega, Kuruvilla John, David Haas, Torsten M. Eckstein, Maher Kali, Christine Welch, Thomas Petrie Jan 2015

Resolution Of Crohn's Disease And Complex Regional Pain Syndrome Following Treatment Of Paratuberculosis, J. Todd Kuenstner, William Chamberlin, Saleh A. Naser, Michael T. Collins, Coad Thomas Dow, John M. Aitken, Stuart Weg, Grzegorz Telega, Kuruvilla John, David Haas, Torsten M. Eckstein, Maher Kali, Christine Welch, Thomas Petrie

Faculty Bibliography 2010s

A cohort of family members with various chronic diseases including Crohn's disease, asthma, complex regional pain syndrome, hypothyroidism, type 1 diabetes mellitus, and lymphangiomatosis and/or evidence of infection by Mycobacterium avium subsp. paratuberculosis (MAP) are described in this series of case reports. MAP was cultured from the blood of three members affected by the first five diseases and there was accompanying elevated anti-MAP IgG in two members. The patient affected by the sixth disease has a markedly elevated anti-MAP titer. The two patients affected by the first four diseases have been treated with a combination of anti-MAP antibiotics and ultraviolet …

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A Faith-Based Primary Diabetes Prevention Intervention For At-Risk Puerto Rican Adults: A Feasibility Study, Sylvia Torres-Thomas Jan 2015

A Faith-Based Primary Diabetes Prevention Intervention For At-Risk Puerto Rican Adults: A Feasibility Study, Sylvia Torres-Thomas

Electronic Theses and Dissertations

Diabetes is a serious health threat that disproportionately affects Hispanics of Puerto Rican heritage. Current evidence supports diabetes prevention programs to change health behaviors in people who are at risk and thus prevent the development of type 2 diabetes. However, few interventions exist for Hispanics, and even fewer have been designed for Puerto Rican adults. A literature review of community-based diabetes prevention programs involving at-risk Hispanics was conducted using a cultural sensitivity framework to determine the state of the science and identify gaps in knowledge regarding diabetes prevention for Puerto Ricans. An integrated theoretical framework was developed using constructs from …

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Can I Get An Amen? Central Florida Black Pastors' Perceptions Of The Impact Of The Black Church In The Black Community, Jeffrey Williamson Jan 2015

Can I Get An Amen? Central Florida Black Pastors' Perceptions Of The Impact Of The Black Church In The Black Community, Jeffrey Williamson

Electronic Theses and Dissertations

This study uses phenomenological methods to answer the research question, “what do black pastors perceive as the role of the church in the black community?” I asked 20 Central Florida black pastors 17 questions, most of them open-ended, to determine their perceptions of the current black church. First, these pastors are dismayed at the condition and the position of the current black church. They view the history the black church as strong and stalwart, and the Civil Rights Movement as an example of what the institution is capable of doing and being. Second, they perceive the primary roadblock of the …

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Regulation Of Vldl Trafficking By Orp 10, Philip A. Wessels Jan 2015

Regulation Of Vldl Trafficking By Orp 10, Philip A. Wessels

HIM 1990-2015

Of the challenges facing the improvement of human health, none has taken the forefront quite like the endeavor to discover novel treatments for heart disease. As heart disease has now become the leading cause of death throughout the world [1], the medical community has made incredible strides in the mission to treat atherosclerosis which is the major contributor to heart disease. Very Low Density Lipoproteins (VLDL) are secreted by the liver and subsequently converted to Low Density Lipoproteins (LDL). Many factors contribute to the narrowing of the arterial walls, however oxidized LDL is the main factor that leads to the …

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Perceived Social Support And Self-Care In Patients Hospitalized With Heart Failure, Lyne Chamberlain Jan 2015

Perceived Social Support And Self-Care In Patients Hospitalized With Heart Failure, Lyne Chamberlain

Electronic Theses and Dissertations

Problem: Heart failure is the most frequent cause for hospital readmissions in Medicare recipients, with an estimated annual cost of $12 billion. Heart failure hospitalizations are also an independent risk factor for increased mortality. Self-care, thought to be enhanced by perceived social support, is key to managing this syndrome, and up to 50% of readmissions are considered the result of inadequate self-care. Purpose: To evaluate perceived social support and self-care characteristics of patients hospitalized with an exacerbation of heart failure, and to compare these characteristics with a study of ambulatory patients with heart failure. In addition, to assess the relationship …

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Way Of The Butterfly: A Journey Towards Transformation Through Self-Portraits In-Between, Masami Koshikawa Jan 2015

Way Of The Butterfly: A Journey Towards Transformation Through Self-Portraits In-Between, Masami Koshikawa

Electronic Theses and Dissertations

It has not been easy for me to talk about myself or describe my feelings or thoughts. Coming from Japan, a collective society, we typically are not raised to do so. Throughout the MFA program at UCF, I have shared my feelings and thoughts through my work. It is important to discuss and inform others of our cultural similarities and differences so that we may gain a better understanding of each other. This process has helped me grow not only on an artistic level, but also on a personal level. My journey towards integration has led me to a meaningful …

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Persons, Houses, And Material Possessions: Second Spanish Period St. Augustine Society, Daniel Velasquez Jan 2015

Persons, Houses, And Material Possessions: Second Spanish Period St. Augustine Society, Daniel Velasquez

Electronic Theses and Dissertations

St. Augustine in the late eighteenth and early nineteenth centuries was a prosperous, multi-ethnic community that boasted trade connections throughout the Atlantic world. Shipping records demonstrate that St. Augustine had access to a wide variety of goods, giving residents choices in what they purchased, and allowing them to utilize their material possessions to display and reinforce their status. Likewise, their choice of residential design and location allowed them to make statements in regards to their place in the social order. St. Augustine was a unique city in the Spanish Empire; the realities of frontier living meant that inter-ethnic connection were …

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Body Mass Bias Mitigation For Females In Military Physical Readiness Testing Through Load Carriage Implementation, Aaron Yeaton Jan 2015

Body Mass Bias Mitigation For Females In Military Physical Readiness Testing Through Load Carriage Implementation, Aaron Yeaton

Electronic Theses and Dissertations

The US Military requires specific fitness testing, known as the Physical Readiness Test (PRT), for its members to determine their overall fitness levels. The test currently being used has been shown to have bias towards heavier mass individuals of up to 20%. Prior research has been completed and several recommendations have been made to eliminate mass bias, but this has been conducted almost exclusively on males. There is very little data and research on military physical fitness testing for women besides combat specific evolution exercises. A possibility exists to eliminate the bias for females through implementing load carriage during PRT …

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The Effects Of Chronic Sleep Deprivation On Sustained Attention: A Study Of Brain Dynamic Functional Connectivity, Yiling He Jan 2015

The Effects Of Chronic Sleep Deprivation On Sustained Attention: A Study Of Brain Dynamic Functional Connectivity, Yiling He

Electronic Theses and Dissertations

It is estimated that about 35-40% of adults in the U.S. suffer from insufficient sleep. Chronic sleep deprivation has become a prevalent phenomenon because of contemporary lifestyle and work-related factors. Sleep deprivation can reduce the capabilities and efficiency of attentional performance by impairing perception, increasing effort to maintain concentration, as well as introducing vision disturbance. Thus, it is important to understand the neural mechanisms behind how chronic sleep deprivation impairs sustained attention. In recent years, more attention has been paid to the study of the integration between anatomically distributed and functionally connected brain regions. Functional connectivity has been widely used …

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Evaluation Of Strength And Hydraulic Properties Of Buried Pipe Systems Used For Stormwater Harvesting, Mario Samson Mena Jan 2015

Evaluation Of Strength And Hydraulic Properties Of Buried Pipe Systems Used For Stormwater Harvesting, Mario Samson Mena

Electronic Theses and Dissertations

Water scarcity has been identified as a global issue. Both water harvesting and an efficient water piping system are some of the important factors to meet the water demand. In this study, high-density polyethylene (HDPE) pipes used as an underground storage was evaluated and a Microsoft EXCEL based model was developed, called PIPE-R Model. To study the structural integrity of the pipes, laboratory and field testing were conducted. For the water harvesting, UCF Stormwater Management Academy designed an EXCEL based model to simulate the system's performance to store and redistribute water for an average year. The purpose of PIPE-R Model …

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The Relationship Between Participation In An Academic Intervention Program And Performance In Coursework For At Risk Eighth-Grade Middle School Students, Victoria Hyatt Jan 2015

The Relationship Between Participation In An Academic Intervention Program And Performance In Coursework For At Risk Eighth-Grade Middle School Students, Victoria Hyatt

Electronic Theses and Dissertations

The focus of the research was to examine the academic intervention program implemented to address academic concerns in the middle grades in one large urban school district in central Florida. Educational leaders at all levels are concerned with the choice of one in four students who make the decision to not complete high school coursework, leaving before earning a high school diploma. The researcher examined to what extent, if any, participation in the middle grades academic intervention program affected academic success in coursework and what difference, if any, there were between academic coursework grade point averages and at-risk eligibility factors, …

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The Effect Of A Metalinguistic Approach To Sentence Combining On Written Expression In Eighth Grade Science For Students Who Struggle With Literacy, Lynne Telesca Jan 2015

The Effect Of A Metalinguistic Approach To Sentence Combining On Written Expression In Eighth Grade Science For Students Who Struggle With Literacy, Lynne Telesca

Electronic Theses and Dissertations

Recent data indicate that less than 50% of American secondary students are able to demonstrate grade-level proficiency in reading, writing, and science (National Center for Educational Statistics [NCES], 2007, 2011, 2012a, 2012b). Secondary students* are expected to develop advanced literacy skills, especially in writing, in order to be ready for college and careers. Students are expected to develop these advanced literacy skills, within all academic subjects. In other words, they are expected to develop disciplinary literacy skills. The statistics are alarming overall, but they are particularly alarming in the area of science. Students need strong literacy skills, including written expression, …

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The Scoop, Vol. 1 Issue 10, January 2015, Health Sciences Library Jan 2015

The Scoop, Vol. 1 Issue 10, January 2015, Health Sciences Library

Volume 1

Latest news and events from the Health Sciences Library in our monthly newsletter for January 2015.

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The Impact Of Public Service Motivation On Reentry Managers' Decision-Making Practices, Marie Pryor Jan 2015

The Impact Of Public Service Motivation On Reentry Managers' Decision-Making Practices, Marie Pryor

Electronic Theses and Dissertations

The goal of this exploratory study is to examine the effects of public service motivation (PSM) in predicting decision-making of criminal justice personnel (reentry managers) in the management of former prisoners. The overarching research question seeks to answer if, and in what way, PSM score influences reentry managers' approach to their work with the formerly incarcerated, who are in transition from prison back into the community. The main assumption of this study is that those reentry managers with a higher PSM score will be more inclined to take an assistance oriented approach with former prisoners and be more likely to …

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Executive Branch Documents +, Ucf Libraries Jan 2015

Executive Branch Documents +, Ucf Libraries

Technology Fee Funded Projects

UCF Libraries, in collaboration with the Department of History and Department of Political Science, is requesting $194,381 for the one-time combined purchase of ProQuest Executive Branch Documents, ProQuest U.S. Serial Set Digital Collection, and ProQuest Congressional.

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Mango Language Learning, Ucf Libraries Jan 2015

Mango Language Learning, Ucf Libraries

Technology Fee Funded Projects

The UCF Libraries, in collaboration with Department of Modern Languages, is requesting $137,500 ($140,000 less a $2,500 cost share from UCF Libraries) for the one-time purchase of Mango Languages Learning. This database will benefit UCF students and faculty, especially in programs including Modern Languages, International Affairs and Global Strategies, College of Business Administration, Public Affairs and International Studies.

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Experiences Of Stigma During Sexual Healthcare Visits: A Qualitative Study Of Non-Monogamous Women, Rachael Mccrosky Jan 2015

Experiences Of Stigma During Sexual Healthcare Visits: A Qualitative Study Of Non-Monogamous Women, Rachael Mccrosky

Electronic Theses and Dissertations

Access to health care services is critical to both personal health outcomes and health equity within a community. While non-monogamous behavior is widespread, stigma surrounding consensual non-monogamy can create barriers to health care access. This research outlines the experiences of non-monogamous women during sexual health care visits, how class acts to modify those experiences, the barriers to health care access that they encounter, and the adaptive strategies they employ. The sample for this research was 23 consensually non-monogamous women. Participants were contacted through online support groups, message boards, and snowball sampling. In-depth interviews about their sexual health care experiences were …

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Overexpression Of Human Cu/Zn Superoxide Dismutase In Mice; The Effect Of Increase Superoxide Scavenging On Autonomic Control Of The Heart., Jeffrey Hatcher Jan 2015

Overexpression Of Human Cu/Zn Superoxide Dismutase In Mice; The Effect Of Increase Superoxide Scavenging On Autonomic Control Of The Heart., Jeffrey Hatcher

Electronic Theses and Dissertations

Dysregulation of the autonomic cardiovascular control is a complication of diseases including diabetes, hypertension, sleep apnea, and aging. A common factor in these conditions is an increase in reactive oxygen species (ROS) in neural, cardiac, and endothelial tissues. Cu/Zn superoxide dismutase (SOD1) is an intracellular anti-oxidant enzyme that catalyzes dismutation of the superoxide anion (O2.-) to hydrogen peroxide (H2O2). Expression and function of this enzyme are diminished in pathologies that impair cardiovascular autonomic control. This study employed mice overexpressing a transgene for human SOD1 (hSOD1) to determine if its overexpression would alter autonomic regulation of BP, HR, and BRS in …

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Damage Detection Methodologies For Structural Health Monitoring Of Thin-Walled Pressure Vessels, Arturo Modesto Jan 2015

Damage Detection Methodologies For Structural Health Monitoring Of Thin-Walled Pressure Vessels, Arturo Modesto

Electronic Theses and Dissertations

There is a need in exploring structural health monitoring technologies for the composite structures particularly aged Composite Overwrapped Pressure Vessels (COPVs) for the current and future implementation of COPVs for space missions. In this study, the research was conducted in collaboration with NASA Kennedy Space Center and also NASA Marshall Space and Flight Center engineers. COPVs have been used to store inert gases like helium (for propulsion) and nitrogen (for life support) under varying degrees of pressure onboard the orbiter since the beginning of the Space Shuttle Program. After the Columbia accident, the COPVs were re-examined and different studies (e.g. …

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Helping Mothers Defend Their Decision To Breastfeed, Kandis Natoli Jan 2015

Helping Mothers Defend Their Decision To Breastfeed, Kandis Natoli

Electronic Theses and Dissertations

The United States has established breastfeeding as an important health indicator within the Healthy People agenda. Healthy People target goals for breastfeeding initiation, duration, and exclusivity remain unmet. The US Surgeon General's Office reports that lack of knowledge and widespread misinformation about breastfeeding are barriers to meeting Healthy People goals. Breastfeeding mothers are vulnerable to messages that cast doubt on their ability to breastfeed. Very little research has examined specific approaches to help people resist negative messages about health beliefs and behaviors. The objective of this quasi-experimental study was to test an intervention designed to help mothers defend their breastfeeding …

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Alcohol Consumption, Frailty, And The Mediating Role Of C-Reactive Protein In Older Adults, Mona Shah Jan 2015

Alcohol Consumption, Frailty, And The Mediating Role Of C-Reactive Protein In Older Adults, Mona Shah

Electronic Theses and Dissertations

Frailty is a well-established indicator of late-life decline and is accompanied by higher rates of comorbidity and disability. Meanwhile, an estimated 41% of adults over the age of 65 report consuming alcohol – an identified health risk and protective factor depending on dosage. Given that the demographic group of older Americans is projected to double by the year 2050, identification of frailty risk and protective factors is imperative. The goals of this thesis are to: (1) identify how varying levels of alcohol consumption relate to frailty, and (2) elucidate a possible mechanism that accounts for the relationship between alcohol consumption …

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