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Homophobia And Hiv Transmission: A Six-Country Comparative Analysis, Tiernan Middleton Jan 2015

Homophobia And Hiv Transmission: A Six-Country Comparative Analysis, Tiernan Middleton

HIM 1990-2015

This interdisciplinary study combines epidemiological data with anthropological theory to investigate the relationship between HIV transmission rates and systemic homophobia. Previous research has illustrated the link between high levels of structural violence and structural stigma to increased risk of diseases such as the link between African-Americans and heart disease. This study investigates the relationship between systemic homophobia and HIV transmission rates. Through operationalizing homophobia into seven distinct factors, I evaluated systemic homophobia in six countries, assigning a score 1-10 to each factor using secondary source aggregation. I compared composite scores, as well as scores in each operationalized factor to HIV …


Development Of A Fluorescent Drug Screening Platform For Inhibitors Of Mycobacterium Tuberculosis Protein-Protein Interactions, Zina Versfeld Jan 2015

Development Of A Fluorescent Drug Screening Platform For Inhibitors Of Mycobacterium Tuberculosis Protein-Protein Interactions, Zina Versfeld

HIM 1990-2015

Tuberculosis (TB) is a respiratory disease caused by Mycobacterium tuberculosis (Mtb) that kills around 1.3 million people annually. Multi-drug resistant TB (MDR-TB) strains are increasingly encountered, in part resulting from shortcomings of current TB drug regimens that last between six to nine months. Patients may stop taking the antibiotics during their allotted regimen, leading to drug resistant TB strains. Novel drug screening platforms are therefore necessary to find drugs effective against MDR-TB. In order to discover compounds that target under-exploited pathways that may be essential only in vivo, the proposed screening platform will use a novel approach to drug discovery …


The Plight Of Being Unrecognized In The United States: Should Undocumented Immigrants Be Licensed To Drive In Florida?, Jennifer Wilford Jan 2015

The Plight Of Being Unrecognized In The United States: Should Undocumented Immigrants Be Licensed To Drive In Florida?, Jennifer Wilford

HIM 1990-2015

The United States of America is facing an important decision. Should illegal immigrants be allowed to obtain driver’s licenses? Thus far ten states and the District of Columbia as well as Puerto Rico have passed laws permitting this to come into fruition. The purpose of this thesis is to gain an understanding of the significance that licensing laws have on this country. This thesis will compare the views and beliefs of both the proponents and opponents to this law. This thesis also discusses how Florida is deeply affected due to its large Hispanic immigrant population. This issue is laden with …


21st Annual Joseph C. Andrews Mentoring Celebration, February 25, 2015, Black Faculty And Staff Association Jan 2015

21st Annual Joseph C. Andrews Mentoring Celebration, February 25, 2015, Black Faculty And Staff Association

BFSA Collection - Mentoring Breakfast Materials

No abstract provided.


Resource Allocation And Load-Shedding Policies Based On Markov Decision Processes For Renewable Energy Generation And Storage, Edwards Jimenez Jan 2015

Resource Allocation And Load-Shedding Policies Based On Markov Decision Processes For Renewable Energy Generation And Storage, Edwards Jimenez

Electronic Theses and Dissertations

In modern power systems, renewable energy has become an increasingly popular form of energy generation as a result of all the rules and regulations that are being implemented towards achieving clean energy worldwide. However, clean energy can have drawbacks in several forms. Wind energy, for example can introduce intermittency. In this thesis, we discuss a method to deal with this intermittency. In particular, by shedding some specific amount of load we can avoid a total system breakdown of the entire power plant. The load shedding method discussed in this thesis utilizes a Markov Decision Process with backward policy iteration. This …


Environmentalism And Environmental Constitutional Ballot Initiatives In Florida: The Elements Of Support For Amendment One In 2014 In The Context Of Current Environmental Attitudes., Michael Jones Jan 2015

Environmentalism And Environmental Constitutional Ballot Initiatives In Florida: The Elements Of Support For Amendment One In 2014 In The Context Of Current Environmental Attitudes., Michael Jones

Electronic Theses and Dissertations

Americans express support for “the environment” with environmental support cutting across political and demographic differences and cleavages. In the past 15 years, however, period effects, political sorting, and the emergence of a powerful anti-environmental movement have lessened the generalized levels of environmental support. Using the 2012 CCES survey, the expressed attitudes regarding multiple environmental issues found significant differences in levels of environmental support nationally by party, Tea Party attitudes, ideology, and certain demographic characteristics. For Floridians, the differences between the most pro-environmental respondents and the most anti-environmental are narrower; partisan identification itself is not significant in environmental attitudes; but ideology, …


Influence Of Personal And State Level Variables On Perception Of State Emergency Management Network Resilience In 47 States, Victoria Jennison Jan 2015

Influence Of Personal And State Level Variables On Perception Of State Emergency Management Network Resilience In 47 States, Victoria Jennison

Electronic Theses and Dissertations

Emergency management coordination in the United States has fallen victim to over a century of strategies to organize, reorganize, consolidate, or decentralize disaster preparedness, planning and response. Regardless of the agency in charge at the federal level, individual citizens have been responsible for their own well-being immediately after any disaster or emergency event for more than 100 years because it takes time to mobilize and deliver aid. The system most often charged with managing that mobilization during an emergency event that exceeds the response capacity of local public safety agencies is the state emergency management network. Many entities in a …


Safety Climate And Safety Outcomes In Aircraft Maintenance: A Mediating Effect Of Employee Turnover And Safety Motivation, Muhanna Alnoaimi Jan 2015

Safety Climate And Safety Outcomes In Aircraft Maintenance: A Mediating Effect Of Employee Turnover And Safety Motivation, Muhanna Alnoaimi

Electronic Theses and Dissertations

Aircraft maintenance is viewed as a critical safety component in general and military aviation industries, and thus it is crucial to identify the factors that may affect aircraft maintenance. Because the safety climate is considered as a leading indicator of safety performance and safety outcomes, this study utilized this safety climate approach to develop a model which can explain the relationships between employee turnover, safety motivation, self-reported unsafe acts, reporting unsafe behaviors, incidents, and injuries in the aviation maintenance environment. This study included a sample of 283 technicians in military aircraft maintenance units who participated in a cross-sectional random survey. …


Destination Competitiveness: A Comparative Study Of Hong Kong, Macau And Singapore, Louise Todd, Anna Leask, Alan Fyall Jan 2015

Destination Competitiveness: A Comparative Study Of Hong Kong, Macau And Singapore, Louise Todd, Anna Leask, Alan Fyall

Rosen Faculty Scholarship and Creative Works

This article presents a comparative study of the destination competitiveness of Hong Kong, Singapore, and Macau and those strategies developed to enhance their future positions in the global destination “marketplace.” The methodology adopted is secondary in nature in that a critical review of the existing literature was conducted along with a synthesis of current practices across the three city-state destinations. The 15 Cs Framework provides the research parameters for the study in that it advocates an inclusive approach to those challenges and opportunities facing destinations as they seek to enhance their overall competitiveness. In particular, the study explores the specific …


Peering Into The Future: Three Essays On The Nascent Phenomenon Of Collaborative Consumption, Rebeca Dellegrazie-Perren Jan 2015

Peering Into The Future: Three Essays On The Nascent Phenomenon Of Collaborative Consumption, Rebeca Dellegrazie-Perren

Electronic Theses and Dissertations

The primary objective of this dissertation is to examine the theoretical and practical implications of the collaborative consumption phenomenon for individuals, businesses and society. To accomplish this goal, a research approach at three levels of analysis is used to explore how market institutions and consumer practices negotiate a social order that combines the social domain of peers with the economic domain of market exchange. The first essay of the dissertation approaches this objective from a macro level to examine how social order is produced and sustained through the systemic interactions of service firms and peers. This essay provides a framework …


Disciplinary Mythologies: A Rhetorical-Cultural Analysis Of Performance Enhancement Technologies In Sports, John Lamothe Jan 2015

Disciplinary Mythologies: A Rhetorical-Cultural Analysis Of Performance Enhancement Technologies In Sports, John Lamothe

Electronic Theses and Dissertations

In sports discourse, the relationship between athletics and technology is often paradoxical. On the one hand, modern sports rely on technology at every level, from training and tracking of players to the equipment and apparel used by athletes to the game strategies and playing fields themselves. Nearly all of these technologies are intended to increase athletic performance on some level. And yet, certain performance enhancement technologies can be criticized for being antithetical to the spirit of sports, which is framed as being a strictly natural and pure human endeavor. Using a rhetorical-cultural methodological approach, popular sports discourse is analyzed to …


The Ct20 Peptide As An Agent For Cancer Treatment, Rania Bassiouni Jan 2015

The Ct20 Peptide As An Agent For Cancer Treatment, Rania Bassiouni

Electronic Theses and Dissertations

Due to cancer recurrence and the development of drug resistance, metastatic breast cancer is a leading cause of death in women. In the search for a new therapeutic to treat metastatic disease, we discovered CT20p, an amphipathic peptide based on the C-terminus of Bax. Due to inherent properties of its sequence and similarity to antimicrobial peptides, CT20p is a promising cytotoxic agent whose activity is distinct from the parent protein (e.g. does not cause apoptosis). CT20p is not membrane permeable but can be introduced to cells using polymeric nanoparticles, a method that promotes efficient delivery of the peptide into the …


Differential Expression Of Proteins Involved In Vldl Trafficking Causes Reduced Vldl Secretion In Male Ames Dwarf Mice, Faisal Ahmed Moinuddin Jan 2015

Differential Expression Of Proteins Involved In Vldl Trafficking Causes Reduced Vldl Secretion In Male Ames Dwarf Mice, Faisal Ahmed Moinuddin

Electronic Theses and Dissertations

Cardiovascular diseases (CVDs) have been recorded as the number one cause of death worldwide, accounting for 32% of total deaths annually. More than two-thirds of all CVD cases are associated with atherosclerosis, which is the accumulation of fats and other substances causing plaque formation in the interior walls of major arteries. This leads to narrowing of the lumen and hardening of the arteries, ultimately resulting in angina, heart attack and/or stroke. Studies have shown that the pathogenesis of atherosclerosis and associated CVDs is strongly linked to elevated secretion of liver-specific lipoproteins called very-low-density-lipoprotein (VLDL). VLDLs are crucial lipoproteins responsible for …


Pre And Post Implementation Evaluation Of An Emergency Department Severe Sepsis Alert And Practice Protocol, Darleen Williams Jan 2015

Pre And Post Implementation Evaluation Of An Emergency Department Severe Sepsis Alert And Practice Protocol, Darleen Williams

Electronic Theses and Dissertations

Severe sepsis kills an estimated 1,400 people worldwide every day. This often fatal infectious process accounts for an estimated 215,000 deaths in the United States (US) annually. The main goal of this project was to evaluate the impact of the Emergency Department Severe Sepsis Alert and Practice Protocol (EDSSAPP) post implementation, on time to first antibiotic administration, length of stay, and mortality in patients admitted via the ORMC ED with severe sepsis. This study evaluated the time to first antibiotic administration, total ED and hospital length of stay (LOS) and mortality of severe sepsis patients either with a severe sepsis …


The Relationship Between Dna's Physical Properties And The Dna Molecule's Harmonic Signature, And Related Motion In Water--A Computational Investigation, Victor Boyer Jan 2015

The Relationship Between Dna's Physical Properties And The Dna Molecule's Harmonic Signature, And Related Motion In Water--A Computational Investigation, Victor Boyer

Electronic Theses and Dissertations

This research investigates through computational methods whether the physical properties of DNA contribute to its harmonic signature, the uniqueness of that signature if present, and motion of the DNA molecule in water. When DNA is solvated in water at normal 'room temperature', it experiences a natural vibration due to the Brownian motion of the particles in the water colliding with the DNA. The null hypothesis is that there is no evidence to suggest a relationship between DNA's motion and strand length, while the alternative hypothesis is that there is evidence to suggest a relationship between DNA's vibrational motion and strand …


Integrated Sustainability Assessment Framework For The U.S. Transportation, Nuri Onat Jan 2015

Integrated Sustainability Assessment Framework For The U.S. Transportation, Nuri Onat

Electronic Theses and Dissertations

This dissertation aims to investigate the sustainability impacts of alternative vehicle technologies and develop comprehensive sustainability assessment frameworks to analyze potential impacts of these vehicles in the U.S. In order to assess sustainability impact of vehicle alternatives, life-cycle based models has been extensively used in the literature. Although life cycle-based models are often used for environmental impacts of alternative vehicles, analysis of social and economic impacts of these vehicles has gained a tremendous interest. In this regard, there is a growing interest among the international platform and academia to use the Life Cycle Sustainability Assessment framework to have more informed …


Response Of Streamflow And Sediment Loading In The Apalachicola River, Florida To Climate And Land Use Land Cover Change, Paige Hovenga Jan 2015

Response Of Streamflow And Sediment Loading In The Apalachicola River, Florida To Climate And Land Use Land Cover Change, Paige Hovenga

Electronic Theses and Dissertations

Located in Florida's panhandle, the Apalachicola River is the southernmost reach of the Apalachicola-Chattahoochee-Flint (ACF) River basin. Streamflow and sediment drains to Apalachicola Bay in the Northern Gulf of Mexico, directly influencing the ecology of the region, in particular seagrass and oyster production. The objective of this study is to evaluate the response of runoff and sediment loading in the Apalachicola River under projected climate change scenarios and land use / land cover (LULC) change. A hydrologic model using the Soil Water Assessment Tool (SWAT) was developed for the Apalachicola region to simulate daily discharge and sediment load under present …


Energy Harvesting Toward The Vibration Reduction Of Turbomachinery Blades Via Resonance Frequency Detuning, Taylor Hynds Jan 2015

Energy Harvesting Toward The Vibration Reduction Of Turbomachinery Blades Via Resonance Frequency Detuning, Taylor Hynds

Electronic Theses and Dissertations

Piezoelectric-based energy harvesting devices provide an attractive approach to powering remote devices as ambient mechanical energy from vibrations is converted to electrical energy. These devices have numerous potential applications, including actuation, sensing, structural health monitoring, and vibration control -- the latter of which is of particular interest here. This work seeks to develop an understanding of energy harvesting behavior within the framework of a semi-active technique for reducing turbomachinery blade vibrations, namely resonance frequency detuning. In contrast with the bulk of energy harvesting research, this effort is not focused on maximizing the power output of the system, but rather providing …


The Influence Of Alloying Additions On Diffusion And Strengthening Of Magnesium, Catherine Kammerer Jan 2015

The Influence Of Alloying Additions On Diffusion And Strengthening Of Magnesium, Catherine Kammerer

Electronic Theses and Dissertations

Magnesium alloys are being developed as advanced materials for structural applications where reduced weight is a primary motivator. Alloying can enhance the properties of magnesium without significantly affecting its density. Essential to alloy development, inclusive of processing parameters, is knowledge of thermodynamic, kinetic, and mechanical behavior of the alloy and its constituents. Appreciable progress has been made through conventional development processes, but to accelerate development of suitable wrought Mg alloys, an integrated Materials Genomic approach must be taken where thermodynamics and diffusion kinetic parameters form the basis of alloy design, process development, and properties-driven applications. The objective of this research …


Drinking Water Infrastructure Assessment With Teleconnection Signals, Satellite Data Fusion And Mining, Sanaz Imen Jan 2015

Drinking Water Infrastructure Assessment With Teleconnection Signals, Satellite Data Fusion And Mining, Sanaz Imen

Electronic Theses and Dissertations

Adjustment of the drinking water treatment process as a simultaneous response to climate variations and water quality impact has been a grand challenge in water resource management in recent years. This desired and preferred capability depends on timely and quantitative knowledge to monitor the quality and availability of water. This issue is of great importance for the largest reservoir in the United States, Lake Mead, which is located in the proximity of a big metropolitan region - Las Vegas, Nevada. The water quality in Lake Mead is impaired by forest fires, soil erosion, and land use changes in nearby watersheds …


Trihalomethane Removal And Re-Formation In Spray Aeration Processes Treating Disinfected Groundwater, Cassandra Smith Jan 2015

Trihalomethane Removal And Re-Formation In Spray Aeration Processes Treating Disinfected Groundwater, Cassandra Smith

Electronic Theses and Dissertations

Historically, chlorination has been widely utilized as a primary and secondary disinfectant in municipal water supplies. Although chlorine disinfection is effective in inactivating pathogenic microbes, the use of chlorine creates the unintentional formation of regulated chemicals. On January 4, 2006, the United States Environmental Protection Agency (EPA) promulgated the Stage 2 Disinfectants/Disinfection by-product rule (DBPR) that focuses on public health protection by limiting exposure to four trihalomethanes (THM) and five haloacetic acids (HAA5), formed when chlorine is used for microbial pathogen control. This thesis examines post-aeration TTHM formation when employing spray-aeration processes to remove semi-volatile TTHMs from chlorinated potable water …


Fiber-Reinforced Polymer (Frp) Composites In Retrofitting Of Concrete Structures: Polyurethane Systems Versus Epoxy Systems, Elie El Zghayar Jan 2015

Fiber-Reinforced Polymer (Frp) Composites In Retrofitting Of Concrete Structures: Polyurethane Systems Versus Epoxy Systems, Elie El Zghayar

Electronic Theses and Dissertations

Fiber reinforced polymer (FRP) composites have been of interest to the structural engineering society since the earliest days of FRP composites industry. The use of such systems has been implemented in both new construction and for repair and rehabilitation of existing structures. Since the 1980s, researchers have developed a significant body of knowledge to use FRP composites in infrastructure applications; however, most of this established knowledge was concentrated on the use of traditional epoxy (EP) systems (epoxy matrix FRPs and epoxy adhesives). FRP composites with polyurethane (PU) matrices and adhesives have recently attracted the attention of a few researchers due …


The Effect Of Videogame Play On Robotic Surgery Skill Acquisition, Alyssa Tanaka Jan 2015

The Effect Of Videogame Play On Robotic Surgery Skill Acquisition, Alyssa Tanaka

Electronic Theses and Dissertations

Robotic surgery uses innovative technology to transcend a surgeon's skills when performing complex procedures. Currently, the only FDA approved robotic system is Intuitive's da Vinci Surgical System. While this system offers many advantages over other minimally invasive techniques, it also introduces a need for specialized training. Virtual reality simulators have emerged as valuable tools for standardized and objective robotic surgery skill training and assessments. In recent years, the idea of using video game technology in surgical education for laparoscopy has also been explored; however few have attempted to make a connection between video game experience and robotic surgical skills. Thus, …


Design, Fabrication, And Interrogation Of Integrated Wireless Saw Temperature Sensors, Mark Gallagher Jan 2015

Design, Fabrication, And Interrogation Of Integrated Wireless Saw Temperature Sensors, Mark Gallagher

Electronic Theses and Dissertations

Wireless surface acoustic wave (SAW) sensors offer unique advantages over other sensor technologies because of their inherent ability to operate in harsh environments and completely passive operation, providing a reliable, maintenance-free life cycle. For certain SAW sensor applications the challenge is building a wirelessly interrogatable device with the same lifetime as the SAW substrate. The design of these application intensive sensors is complicated by the degradation of device bond wires, die adhesive, and antenna substrate. In an effort to maximize the benefits of the platform, this dissertation demonstrates wafer-level integrated SAW sensors that directly connect the thin film SAW to …


The Large Ribosomal Subunit Protein L9 Enables The Growth Of Ef-P Deficient Cells And Enhances Small Subunit Maturation, Anusha Naganathan, Matthew P. Wood, Sean D. Moore Jan 2015

The Large Ribosomal Subunit Protein L9 Enables The Growth Of Ef-P Deficient Cells And Enhances Small Subunit Maturation, Anusha Naganathan, Matthew P. Wood, Sean D. Moore

Faculty Bibliography 2010s

The loss of the large ribosomal protein L9 causes a reduction in translation fidelity by an unknown mechanism. To identify pathways affected by L9, we identified mutants of E. coli that require L9 for fitness. In a prior study, we characterized L9-dependent mutations in the essential GTPase Der (EngA). Here, we describe a second class of L9-dependent mutations that either compromise or inactivate elongation factor P (EF-P, eIF5A in eukaryotes). Without L9, Delta efp cells are practically inviable. Cell fractionation studies revealed that, in both the Der and EF-P mutant cases, L9's activity reduces immature 16S rRNA in 30S particles …


Fibroblast Growth Factor-9 Enhances M2 Macrophage Differentiation And Attenuates Adverse Cardiac Remodeling In The Infarcted Diabetic Heart, Dinender K. Singla, Reetu D. Singla, Latifa S. Abdelli, Carley Glass Jan 2015

Fibroblast Growth Factor-9 Enhances M2 Macrophage Differentiation And Attenuates Adverse Cardiac Remodeling In The Infarcted Diabetic Heart, Dinender K. Singla, Reetu D. Singla, Latifa S. Abdelli, Carley Glass

Faculty Bibliography 2010s

Inflammation has been implicated as a perpetrator of diabetes and its associated complications. Monocytes, key mediators of inflammation, differentiate into pro-inflammatory M1 macrophages and anti-inflammatory M2 macrophages upon infiltration of damaged tissue. However, the inflammatory cell types, which propagate diabetes progression and consequential adverse disorders, remain unclear. The current study was undertaken to assess monocyte infiltration and the role of fibroblast growth factor-9 (FGF-9) on monocyte to macrophage differentiation and cardioprotection in the diabetic infarcted heart. Db/db diabetic mice were assigned to sham, myocardial infarction (MI), and MI+FGF-9 groups. MI was induced by permanent coronary artery ligation and animals were …


Nanoporous Ge Thin Film Production Combining Ge Sputtering And Dopant Implantation, Jacques Perrin Toinin, Alain Portavoce, Khalid Hoummada, Michaël Texier, Maxime Bertoglio, Sandrine Bernardini, Marco Abbarchi, Lee Chow Jan 2015

Nanoporous Ge Thin Film Production Combining Ge Sputtering And Dopant Implantation, Jacques Perrin Toinin, Alain Portavoce, Khalid Hoummada, Michaël Texier, Maxime Bertoglio, Sandrine Bernardini, Marco Abbarchi, Lee Chow

Faculty Bibliography 2010s

In this work a novel process allowing for the production of nanoporous Ge thin films is presented. This process uses the combination of two techniques: Ge sputtering on SiO2 and dopant ion implantation. The process entails four successive steps: (i) Ge sputtering on SiO2, (ii) implantation preannealing, (iii) high-dose dopant implantation, and (iv) implantation postannealing. Scanning electron microscopy and transmission electron microscopy were used to characterize the morphology of the Ge film at different process steps under different postannealing conditions. For the same postannealing conditions, the Ge film topology was shown to be similar for different implantation doses and different …


Effects Of Beta-Hydroxy-Beta-Methylbutyrate Free Acid Ingestion And Resistance Exercise On The Acute Endocrine Response, Jeremy R. Townsend, Jay R. Hoffman, Adam M. Gonzalez, Adam R. Jajtner, Carleigh H. Boone, Edward H. Robinson, Gerald T. Mangine, Adam J. Wells, Maren S. Fragala, David H. Fukuda, Jeffrey R. Stout Jan 2015

Effects Of Beta-Hydroxy-Beta-Methylbutyrate Free Acid Ingestion And Resistance Exercise On The Acute Endocrine Response, Jeremy R. Townsend, Jay R. Hoffman, Adam M. Gonzalez, Adam R. Jajtner, Carleigh H. Boone, Edward H. Robinson, Gerald T. Mangine, Adam J. Wells, Maren S. Fragala, David H. Fukuda, Jeffrey R. Stout

Faculty Bibliography 2010s

Objective. To examine the endocrine response to a bout of heavy resistance exercise following acute beta-hydroxy-beta-methylbutyrate free acid (HMB-FA) ingestion. Design. Twenty resistance trained men were randomized and consumed either 1 g of HMB-FA (BetaTor) or placebo (PL) 30 min prior to performing an acute heavy resistance exercise protocol. Blood was obtained before (PRE), immediately after (IP), and 30 min after exercise (30P). Circulating concentrations of testosterone, growth hormone (GH), insulin-like growth factor (IGF-1), and insulin were assayed. Data were analyzed with a repeated measures ANOVA and area under the curve (AUC) was analyzed by the trapezoidal rule. Results. The …


Determining Origin In A Migratory Marine Vertebrate: A Novel Method To Integrate Stable Isotopes And Satellite Tracking, Hannah B. Vander Zanden, Anton D. Tucker, Kristen M. Hart, Margaret M. Lamont, David S. Addison, Katherine L. Mansfield, Katrina F. Phillips, Michael B. Wunder, Gabriel J. Bowen, Mariela Pajuelo, Alan B. Bolten, Karen A. Bjorndal Jan 2015

Determining Origin In A Migratory Marine Vertebrate: A Novel Method To Integrate Stable Isotopes And Satellite Tracking, Hannah B. Vander Zanden, Anton D. Tucker, Kristen M. Hart, Margaret M. Lamont, David S. Addison, Katherine L. Mansfield, Katrina F. Phillips, Michael B. Wunder, Gabriel J. Bowen, Mariela Pajuelo, Alan B. Bolten, Karen A. Bjorndal

Faculty Bibliography 2010s

Stable isotope analysis is a useful tool to track animal movements in both terrestrial and marine environments. These intrinsic markers are assimilated through the diet and may exhibit spatial gradients as a result of biogeochemical processes at the base of the food web. In the marine environment, maps to predict the spatial distribution of stable isotopes are limited, and thus determining geographic origin has been reliant upon integrating satellite telemetry and stable isotope data. Migratory sea turtles regularly move between foraging and reproductive areas. Whereas most nesting populations can be easily accessed and regularly monitored, little is known about the …


Defining The Catalytic Activity Of Nanoceria In The P23h-1 Rat, A Photoreceptor Degeneration Model, Lily L. Wong, Quentin N. Pye, Lijuan Chen, Sudipta Seal, James F. Mcginnis Jan 2015

Defining The Catalytic Activity Of Nanoceria In The P23h-1 Rat, A Photoreceptor Degeneration Model, Lily L. Wong, Quentin N. Pye, Lijuan Chen, Sudipta Seal, James F. Mcginnis

Faculty Bibliography 2010s

Purpose Inorganic catalytic nanoceria or cerium oxide nanoparticles (CeNPs) are bona fide antioxidants that possess regenerative radical scavenging activities in vitro. Previously, we demonstrated that CeNPs had neuroprotective and anti-angiogenic properties in rodent retinal degeneration and neovascularization models. However, the cellular mechanisms and duration of the catalytic activity of CeNPs in preventing photoreceptor cell loss are still unknown. In this study, we sought to answer these questions using the P23H-1 rat, an autosomal dominant retinitis pigmentosa (adRP) model. Methods A single dose of either saline or CeNPs was delivered intravitreally into the eyes of P23H-1 rats at 2-3 weeks of …