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Characteristics Of Covid-19 Vaccine-Hesitant Ucf College Students And Potential Avenues For Increasing Vaccination Rates, Justin A. Barthel Jan 2022

Characteristics Of Covid-19 Vaccine-Hesitant Ucf College Students And Potential Avenues For Increasing Vaccination Rates, Justin A. Barthel

Honors Undergraduate Theses

The COVID-19 pandemic has been an ongoing disaster that has devasted millions of lives. With the development of COVID-19 vaccines in late 2020, there was a potential for populations to gain artificial active immunity in order to prevent future outbreaks. However, despite successful clinical trials, millions of citizens have been hesitant to receive the COVID-19 vaccines (Khubchandani et al., 2021). Demographics of the most prominent US vaccine-hesitant populations consist of ethnic/racial minorities and Republicans groups (Khubchandani et al., 2021). Little information is known about COVID-19 vaccine hesitancy in colleges and universities. Colleges provide an elevated risk for infection through their …

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Terror Management Theory During Covid-19: Individual Differences In Death Anxiety Defenses, Nicole L. Harkrider Jan 2022

Terror Management Theory During Covid-19: Individual Differences In Death Anxiety Defenses, Nicole L. Harkrider

Honors Undergraduate Theses

The present study seeks to determine the relationship between Terror Management Theory (TMT) and various measures of existential anxiety, future consciousness, and future-oriented thinking. By using TMT as a theoretical construct, a scale was devised to measure participants’ protective behaviors relating to the COVID-19 pandemic. Three other scales were utilized, including Lalot’s Future Consciousness Scale (FCS), Strathman’s Consideration of Future Consequences Scale (CFCS), and Weems’ Existential Anxiety Questionnaire (EAQ). The scales were combined into one composite survey along with demographic questions. 315 participants were then administered the collection of scales via an only survey platform. Results indicated strong significant correlations …

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Relationship Between Video Games And Recovery From Work: A Comparison Of Different Genres And Leisure Activities, Jessica A. Gass Jan 2022

Relationship Between Video Games And Recovery From Work: A Comparison Of Different Genres And Leisure Activities, Jessica A. Gass

Honors Undergraduate Theses

Work stress can have a negative impact for both individuals and organizations, warranting research on how to recover from it. This research analyzes how the relationship between video games and work recovery differs depending on the genre of the video game played. In addition, these relationships are compared against the relationships between the recovery experiences and other leisure activities. Participants were asked to provide information on how often they play video games and engage in other leisure activities. In addition, two different measures of the four components of work recovery (psychological detachment from work, relaxation, mastery experiences, and control) were …

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A Retrospective Dosimetry Comparison To Define Uncertainties Found In A Novel Intensity Modulated Electron Therapy (Imet) Treatment Technique For Use In Radiation Therapy, Marco A. Masciantonio Jan 2022

A Retrospective Dosimetry Comparison To Define Uncertainties Found In A Novel Intensity Modulated Electron Therapy (Imet) Treatment Technique For Use In Radiation Therapy, Marco A. Masciantonio

Honors Undergraduate Theses

This study will investigate the difference in radiation at different volumes between traditional electron beam therapy and a novel IMET. The difference in dose will be recorded between the novel IMET and the IMET with a slight shift in the target area. The percent difference between this new model treatment and the model treatment with a shift will be calculated. The main goal of this project is to determine if the target area is still sufficiently treated with this slight shift of the patient in different directions. The percent difference is crucial for the success of this project. It will …

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A Systematic Review And Meta-Analysis Of The Relationship Between The Creb Protein's Neuroplastic Functions And The Implications In Neurodegenerative Diseases: A Possible Link Between Synaptic Plasticity And Neurodegenerative Diseases, Mani Sarmast Jan 2022

A Systematic Review And Meta-Analysis Of The Relationship Between The Creb Protein's Neuroplastic Functions And The Implications In Neurodegenerative Diseases: A Possible Link Between Synaptic Plasticity And Neurodegenerative Diseases, Mani Sarmast

Honors Undergraduate Theses

In this two-part study, I investigated whether the cyclic-adenosine monophosphate response element-binding (CREB) protein has the potential to be clinically modulated as a therapeutic target for the treatment of neurodegenerative diseases. Part one consisted of a systematic review that was conducted on select articles gathered through a stepwise method to explore (1) the relationship between diseased, neurodegenerative brains and levels of active, phosphorylated CREB (pCREB), (2) increased activation of CREB as a treatment for neurodegenerative symptoms, and (3) a potential therapeutic drug for neurodegenerative diseases that can target CREB signaling. The results of the systematic review showed evidence that suggested …

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A Novel Drug To Induce Apoptosis In Advanced Prostate Cancer Cells, Parshva A. Sanghvi Jan 2022

A Novel Drug To Induce Apoptosis In Advanced Prostate Cancer Cells, Parshva A. Sanghvi

Honors Undergraduate Theses

Prostate cancer is one of the leading causes of death for men in America as approximately 1 in 41 men will have prostate cancer. In this research, we focus on enzalutamide-resistant prostate cancer cells as cell resistance to enzalutamide is a prevalent obstacle in treating prostate cancer. We tested a novel compound library at different doses and observed each compound's efficacy in inducing apoptosis in enzalutamide-resistant cells. Furthermore, we analyzed the mechanism by which apoptosis was induced in compounds that showed a high efficacy at lower doses. Overall, we found that Darapladib shows promising results in treating cells that have …

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Sacrificing Sisters: Nurses' Psychological Trauma From The First World War, 1914-1918, Kayla Campana Jan 2022

Sacrificing Sisters: Nurses' Psychological Trauma From The First World War, 1914-1918, Kayla Campana

Electronic Theses and Dissertations, 2020-2023

This thesis examines psychological war trauma nurses experienced during the First World War. Psychological war trauma, or shell shock, as it was commonly known during the war, has largely been identified as a male affliction. In this thesis, I demonstrate that women too, suffered trauma and we can better understand nurses' trauma by applying some of the same analytical techniques that scholars have previously used to examine male combatant trauma. Moreover, I analyze the ways in which contemporary actors, including medical professionals and the public, imagined female trauma, specifically the way nurses' psychological trauma could be understood and articulated. Additionally, …

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Workers, Mothers, And Françaises: The French Communist Party And Women In The Interwar Period (1920 - 1939), Elizabeth Klements Jan 2022

Workers, Mothers, And Françaises: The French Communist Party And Women In The Interwar Period (1920 - 1939), Elizabeth Klements

Electronic Theses and Dissertations, 2020-2023

A survey of the first two decades of the French Communist Party's propaganda reveals a wide range of female imagery, from the androgynous, Soviet-style militant of the 1920s to the fashionable, feminine figure of the 1930s. Earlier scholars noting this discrepancy argued that the Party first adopted the Soviet "new woman," based on the Marxist principle of absolute gender equality but rejected it just over a decade later in order to broaden their appeal to the French masses. These studies, however, were restricted by the limited access to the French Communist Party's interwar-era archives. Using recently-digitized Party meeting records, reports, …

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Addressing Human-Centered Artificial Intelligence: Fair Data Generation And Classification And Analyzing Algorithmic Curation In Social Media, Amirarsalan Rajabi Jan 2022

Addressing Human-Centered Artificial Intelligence: Fair Data Generation And Classification And Analyzing Algorithmic Curation In Social Media, Amirarsalan Rajabi

Electronic Theses and Dissertations, 2020-2023

With the growing impact of artificial intelligence, the topic of fairness in AI has received increasing attention. Artificial intelligence is observed to have caused unanticipated negative consequences. In this dissertation, we address two critical aspects regarding human-centered artificial intelligence (HCAI), a new paradigm for developing artificial intelligence that is ethical, fair, and helps to improve the human condition. In the first part of this dissertation, we investigate the effect that AI curation of contents by social media platforms has on an online discussions, by studying a polarized discussion in the Twitter network. We then develop a network communication model that …

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Synthesis, Characterization, And Modeling Of Thermo-Responsive Hydrogels With Improved Mechanical Strength And Swelling Kinetics, Marilu Ortiz Nieves Jan 2022

Synthesis, Characterization, And Modeling Of Thermo-Responsive Hydrogels With Improved Mechanical Strength And Swelling Kinetics, Marilu Ortiz Nieves

Electronic Theses and Dissertations, 2020-2023

Hydrogels have been extensively studied for use in applications such as tissue engineering, drug delivery systems, wound dressing, actuators, valves, and sensors in Micromechanical Systems (MEMS), among others. Thermo-responsive hydrogels in particular pose various advantages such as their capability to respond to an external stimulus and reverse the response when the stimulus is removed and the ability to imbibe a significant amount of solvent and increase their volume by over 1000%. Extensive research has been conducted to tune and improve hydrogel’s rate and degree of swelling and mechanical properties. Previous work showed that when synthetic clay (Laponite) is cross-linked with …

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From Field To Failure: Detecting And Understanding Reliability Defects In Crystalline Silicon Photovoltaics, Dylan Colvin Jan 2022

From Field To Failure: Detecting And Understanding Reliability Defects In Crystalline Silicon Photovoltaics, Dylan Colvin

Electronic Theses and Dissertations, 2020-2023

Severe pollution levels and the growing influence of climate change have shown that dirty energy sources need renewable and sustainable replacements. The field of photovoltaics (PV) has grown substantially over the years from a niche space solar market to a commodity in large part due to improvements in reliability. Reliability of all materials in a PV module must be considered. The industry has seen an explosion of innovation in cell interconnection technologies with significant market penetration in the past several years. These emerging, less mature technologies require more reliability information to guide improvements. Degradation studies of long-term outdoor exposure and …

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The Direct And Indirect Effects Of Strategic Displacement On Territorial Control In Conventional Civil War, Jennifer Hudson Jan 2022

The Direct And Indirect Effects Of Strategic Displacement On Territorial Control In Conventional Civil War, Jennifer Hudson

Electronic Theses and Dissertations, 2020-2023

Which strategies contribute towards a belligerent's ability to shift territorial control in its favor more quickly than others? This dissertation advances a theory of territorial control dynamics in conventional civil war that places the civilian population at the center of the analysis. Existing scholarship explaining territorial control in conventional civil war has emphasized the role of relative military capabilities, direct military confrontations aimed at territorial conquest, and the existence of established zones of control, with civilians generally residing in areas clearly dominated by one party or another, not in contested areas. As such, theory holds that this makes the civilian …

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Executive Function Coaching: Support For Postsecondary Student Success, Kiera Anderson Jan 2022

Executive Function Coaching: Support For Postsecondary Student Success, Kiera Anderson

Electronic Theses and Dissertations, 2020-2023

The advantages of postsecondary education are numerous and serve as a gateway to increased opportunity. Benefits include improved employment opportunities, lifetime earnings, job satisfaction, access to healthcare and preventative care, and overall better quality of life. In addition, valuable life skills development, including; building new social skills and relationships, developing critical thinking, personal development, how to overcome challenges, time management and organization, and deeper knowledge and understanding of the world. Enrollment rates in postsecondary education are predicted to continue to rise for students with and without disabilities. Students are often underprepared for the transition to college and the levels of …

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Note To Survivors: An Analysis Of Suicide Discourse On Suicide Noted And The Figured World Of Suicide, Breahannah Hilaire Jan 2022

Note To Survivors: An Analysis Of Suicide Discourse On Suicide Noted And The Figured World Of Suicide, Breahannah Hilaire

Electronic Theses and Dissertations, 2020-2023

The purpose of this discourse analytic study was to explore and examine suicide attempt survivors' suicidal discourse. Although there is robust knowledge and quantitative research regarding suicidal ideation and suicide attempts, qualitative research on this population could help to expand what is known about and what can help to prevent future suicide attempts. Often, the research on suicidal ideation and attempts have focused on prevention, intervention, and behavioral risk factors. Prior research concentrates on suicide risk and protective factors, yet little is written about the basis and origin of suicidal ideation and behavior among adolescents. Further, few of these studies …

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Investigating Group Differences Of Mental Health Service Use (Tele-Mental Health, Face-To-Face Counseling, And No Counseling) On Psychological Openness, Levels Of Computer Self-Efficacy, And Coping Behavior In Young Adults During Covid-19, Lea Herbert Jan 2022

Investigating Group Differences Of Mental Health Service Use (Tele-Mental Health, Face-To-Face Counseling, And No Counseling) On Psychological Openness, Levels Of Computer Self-Efficacy, And Coping Behavior In Young Adults During Covid-19, Lea Herbert

Electronic Theses and Dissertations, 2020-2023

Given the severity and prevalence of mental health concerns among young adults, universities and community clinics have been increasingly invested in improving counseling utilization. In addition, the COVID-19 pandemic has forced the development of online therapies. Although the availability of online therapies has increased, the process outcomes of actual service users remain unclear. The Theory of Planned Behavior was used to guide the examination of young adults' use of mental health services, and explore group differences in psychological openness, coping, and computer efficacy based on counseling modality. A total of 248 college-aged participants with three help seeking behaviors (tele-mental health …

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The Effects Of Neural And Mechanical Interventions On Muscle Size Versus Function During Short Term Immobilization Of The Lower Limb, Kylie Harmon Jan 2022

The Effects Of Neural And Mechanical Interventions On Muscle Size Versus Function During Short Term Immobilization Of The Lower Limb, Kylie Harmon

Electronic Theses and Dissertations, 2020-2023

Limb immobilization is a commonly used therapeutic intervention during periods of recovery from injury. To improve rehabilitation outcomes, interventions that curtail the severe decrements in muscular size and strength that occur during immobilization are critically needed. The purpose of this study was to assess the effects of two distinct interventions during one week of knee-joint immobilization on muscular size, strength, and neuromuscular function. Thirty-nine healthy, college-aged adults (21 males and 18 females) participated in this study. Participants were randomized into one of four groups: immobilization only (n = 9) , immobilization + action observation/mental imagery (AOMI) (n = 10), immobilization …

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Financial Sustainability Of Florida Cities: Comparative, Retrospective Modeling For Prospective Municipal Financial Health, Terry Henley Jan 2022

Financial Sustainability Of Florida Cities: Comparative, Retrospective Modeling For Prospective Municipal Financial Health, Terry Henley

Electronic Theses and Dissertations, 2020-2023

The Great Recession produced rising debt, deficits, and exposed vulnerabilities for municipalities in a globalist economy. The two-month COVID recession in 2020 accelerated these burdens; a lagging downturn recently added pressures of reduced economic activity, record inflation, and rising costs in 2022. This dissertation studies how local financial sustainability (FS) and financial condition (FC) approaches can work in concert towards a set of indicators with internal and external categorization to explain municipal financial health (MFH). Unassigned fund balance plus select formal stabilizations measure MFH, are conceptually supported in having retrospective (FC) and prospective (FS) value as an intergenerational resource and …

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Compulsory Conformity In Modern Japanese Culture: An Exploration Of Asexuality In The Works Of Murata Sayaka, Kawakami Mieko, And Kamatani Yuki, Nicholas Colecio Jan 2022

Compulsory Conformity In Modern Japanese Culture: An Exploration Of Asexuality In The Works Of Murata Sayaka, Kawakami Mieko, And Kamatani Yuki, Nicholas Colecio

Electronic Theses and Dissertations, 2020-2023

This thesis investigates the representation of asexual individuals in the works of Murata Sayaka, Kawakami Mieko, and Kamatani Yuki, all of whom are contemporary Japanese writers that portray near–suffocating social environments in their depictions of modern-day Japan. Their texts illustrate the augmented demands Japanese society places upon a cross-section of asexual and neurodivergent individuals. Despite the thematic and character–related similarities in their works, I argue that each author presents a unique interpretation of how these asexual individuals interact with—and try to integrate into—wider Japanese society and mainstream culture. Murata's texts demonstrate an unapologetically radical separatism by invoking an idealized queer …

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Development Of An Hipsc-Cortical Neuron Long-Term Potentiation Model And Its Application To Alzheimer's Disease Modeling And Drug Evaluation, Kaveena Autar Jan 2022

Development Of An Hipsc-Cortical Neuron Long-Term Potentiation Model And Its Application To Alzheimer's Disease Modeling And Drug Evaluation, Kaveena Autar

Electronic Theses and Dissertations, 2020-2023

Alzheimer's disease (AD) is commonly characterized by a loss of cognitive function due to the deterioration of neuronal synapses from the presence of senile amyloid beta-42 (Aß42) plaques. Evaluating cognitive deficits caused by Aß42 using human cortical neurons poses a challenge due to sourcing difficulties, and the use of animal models to assess drug efficacy creates biological hurdles from lack of species translatability. Recent advances in induced-pluripotent stem cell technology have enabled the development of mature, human-based cortical neuron models. The development of an hiPSC-cortical neuron differentiation protocol facilitates the exploration of disease onset and functional analysis from a patient-derived …

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Investigating Mobility Through An Oxygen Isotope Study Of The Medieval Cemetery At Kilroot, County Antrim, Northern Ireland, Hannah Pytleski Jan 2022

Investigating Mobility Through An Oxygen Isotope Study Of The Medieval Cemetery At Kilroot, County Antrim, Northern Ireland, Hannah Pytleski

Electronic Theses and Dissertations, 2020-2023

Mobility is an important, multifaceted process involving complex interactions of culture, politics, and economics while also intersecting with individual identities, like religion, status, gender, and age. As such, a multitude of people from different origins can comprise a settlement or a community, which may be detectable through biogeochemical assessment. This study employs stable oxygen and carbon isotopic analysis to evaluate evidence for residential mobility within the early to late Medieval Kilroot cemetery (c. 6th to 16th centuries A.D.) at County Antrim, Northern Ireland. The site is 2.8 miles (4.5 kilometers) east of Carrickfergus Castle and the surrounding town, which was …

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A Critical Intersectional Analysis Of Black Doulas' Experiences In Maternal Healthcare, Emely Matos Jan 2022

A Critical Intersectional Analysis Of Black Doulas' Experiences In Maternal Healthcare, Emely Matos

Electronic Theses and Dissertations, 2020-2023

According to the U.S. Centers for Disease Control and Prevention (CDC), maternal death ratios are severely racially stratified as African American women face the most significant risk. Currently, Black women are four times more likely to die from pregnancy-related death in the United States than white women. Race disparities in maternal health outcomes may be exacerbated by the Covid-19 pandemic as preliminary research suggests that the pandemic's disproportionate impact on Black communities and existing concerns about Black women's medical treatment may indicate an increase in mortality within the next few years. Racial health disparities reflect the nation's flawed maternal healthcare …

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Development And Validation Of A Counterproductive Work Behavior Situational Judgment Test With An Open-Ended Response Format: A Computerized Scoring Approach, Saba Tavoosi Jan 2022

Development And Validation Of A Counterproductive Work Behavior Situational Judgment Test With An Open-Ended Response Format: A Computerized Scoring Approach, Saba Tavoosi

Electronic Theses and Dissertations, 2020-2023

Due to the many detrimental effects of counterproductive work behavior (CWB), it is important to measure the construct accurately. Despite this, there are some limitations inherent to current CWB measures that are somewhat problematic, including that they contain items that do not apply to all jobs while missing items that are important for other jobs (Bowling & Gruys, 2010). The current study tackles these issues by drawing on the benefits associated with open-ended response situational judgment tests (SJTs), such as them having the potential for more insight from respondents (Finch et al., 2018), to develop an open-ended response CWB SJT. …

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The Impacts Of A Food Pantry On College Students, Courtney Howell Jan 2022

The Impacts Of A Food Pantry On College Students, Courtney Howell

Electronic Theses and Dissertations, 2020-2023

The issue of food insecurity on college campuses has been explored in great depth in the last decade; however, there is much less research on the impacts of interventions such as food pantries. Some scholars suggest that food pantries alone are not enough to make an impact on food insecurity, asserting that, "not a single study has examined the effectiveness of food pantries at decreasing food insecurity on postsecondary education institutions" (Bruening, Argo, Payne-Sturges, and Laska 2017: 1788). This study aimed to gain insight into the student experience of using a food pantry and the impact that it has on …

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Lithium-Ion Battery Prognosis With Variational Hybrid Physics-Informed Neural Networks, Renato Giorgiani Do Nascimento Jan 2022

Lithium-Ion Battery Prognosis With Variational Hybrid Physics-Informed Neural Networks, Renato Giorgiani Do Nascimento

Electronic Theses and Dissertations, 2020-2023

Lithium-ion batteries are an increasingly popular source of power for many electric applications. Applications range from electric cars, driven by thousands of people every day, to existing and future air vehicles, such as unmanned aircraft vehicles (UAVs) and urban air mobility (UAM) drones. Therefore, robust modeling approaches are essential to ensure high reliability levels by monitoring battery state-of-charge (SOC) and forecasting the remaining useful life (RUL). Building principled-based models is challenging due to the complex electrochemistry that governs battery operation, which would entail computationally expensive models not suited for prognosis and health management applications. Alternatively, reduced-order models can be used …

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A Novel Antibody-Dependent Mc-Lr Detecting Biosensor For Early Warning Of Harmful Algal Blooms (Habs), Stephanie Stoll Jan 2022

A Novel Antibody-Dependent Mc-Lr Detecting Biosensor For Early Warning Of Harmful Algal Blooms (Habs), Stephanie Stoll

Electronic Theses and Dissertations, 2020-2023

Microcystins (MCs) are toxins produced by cyanobacteria commonly found in harmful algal blooms (HAB) occurring in many surface waters. Due to their toxicity to humans and other organisms, the World Health Organization (WHO) set a guideline of 1 µg/L for microcystin-leucine-arginine (MC-LR) in drinking water. However, current analytical techniques for the detection of MC-LR such as liquid chromatography-mass spectrometry (LC-MS) and enzyme-linked immunosorbent assay (ELISA) are costly, bulky, time-consuming, and mostly conducted in a laboratory, requiring highly trained personnel. Therefore, an analytical method that can be used in the field for rapid determination is essential. In this study, an Anti-MC-LR/MC-LR/Cysteamine …

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The Use Of Stable Carbon And Nitrogen Isotope Analyses To Examine Diet, Life Course, And Social Identities Among The Meroitic Elite Of Sai Island, Sudan, Rachel Lotze Jan 2022

The Use Of Stable Carbon And Nitrogen Isotope Analyses To Examine Diet, Life Course, And Social Identities Among The Meroitic Elite Of Sai Island, Sudan, Rachel Lotze

Electronic Theses and Dissertations, 2020-2023

The focus of this thesis is to learn more about the diets and lives of Nubian individuals who lived on Sai Island during the Meroitic period (250 BC to AD 250) using an approach based in life history, gender, and social identity theory. These individuals were in buried the cemetery 8-B-52.B and they were part of the elite social class. Dietary analysis was conducted by analyzing the stable carbon and nitrogen isotopes from bulk samples of human bone collagen. A total of 34 bone samples were analyzed, and 31 of those samples were determined to be well-preserved. These data were …

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Analyzing Cut Mark Characteristics On Bone From Chopping/Hacking Tools: Implications For Forensic Analysis, Kelly Mcgehee Jan 2022

Analyzing Cut Mark Characteristics On Bone From Chopping/Hacking Tools: Implications For Forensic Analysis, Kelly Mcgehee

Electronic Theses and Dissertations, 2020-2023

Sharp force trauma (SFT) is a mechanism of traumatic injury in which a tool with a pointed or slanted edge impacts the skin and/or bone, producing a penetrating cut mark. Current assessment of forensic and bioarchaeological contexts typically focuses on evaluating and interpreting traumatic injuries to bone due to cutting and stabbing using small, bladed tools, primarily knives and saws. Minimal research focuses on the damage inflicted by a larger class of chopping/hacking tools. Therefore, the purpose of this research was to experimentally evaluate and analyze macroscopic characteristics of chopping/hacking trauma inflicted on pig bones (Sus scrofa domesticus) to determine …

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Influence Of Nonlinear Multiaxial Matrix Viscoelasticity On Piezoresistivity Of Carbon Nanotube Polymer Composites, Wolfgang Klimm Jan 2022

Influence Of Nonlinear Multiaxial Matrix Viscoelasticity On Piezoresistivity Of Carbon Nanotube Polymer Composites, Wolfgang Klimm

Electronic Theses and Dissertations, 2020-2023

Nanocomposites are prominent candidates to extend the capabilities in areas of established fiber reinforced composites. Carbon nanotubes (CNT) with their outstanding mechanical, electrical, and thermal properties are of particular interest. Especially polymers profit from the addition of CNTs, and can be rendered significantly stiffer, stronger, and even electrically conductive. The resulting electrical conductance is deformation-sensitive, known as piezoresistivity, and is utilized in strain sensing applications. However, the polymer matrix introduces time- and temperature-dependency into the mechanical behavior, known as viscoelasticity, and thus affects the relationship between deformation and electrical conductivity over time. Although piezoresistivity and polymer viscoelasticity have been studied …

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Deciphering The Role And Clinical Application Of The Fgfr4-Klb-Fgf19 Axis In Colorectal Neoplastic Progression, Michael Rohr Jan 2022

Deciphering The Role And Clinical Application Of The Fgfr4-Klb-Fgf19 Axis In Colorectal Neoplastic Progression, Michael Rohr

Electronic Theses and Dissertations, 2020-2023

Colorectal cancer (CRC) is the third most common and third deadliest cancer worldwide with rising incidence rates attributed to environmental risk factors like diet. Investigating how these factors impact carcinogenesis requires an understanding of how transcriptional events evolve with respect to neoplastic progression. We employed meta-transcriptomics and latent trajectory modeling to establish a compendium of profiled healthy, adenoma, and CRC samples scored by their position along a pseudotemporal axis. By interpolating a continuous scale from cross-sectional data, dynamic processes occurring throughout disease progression can be analyzed more accurately. For example, smaller pseudotimes represented pre-malignant dysplasia and was characterized by cellular …

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The Effects Of Traumatic Experiences On Identity Among People With Expressive Language Disorders, Bailey Wagaman Jan 2022

The Effects Of Traumatic Experiences On Identity Among People With Expressive Language Disorders, Bailey Wagaman

Electronic Theses and Dissertations, 2020-2023

This study aims to address the lack of standardized measurement of the effects of trauma on identity. Waterman's (2020) theory, taxonomy, and Trauma Impacts on Identity Functioning Scales were used to evaluate the effects of traumatic brain injury on identity. TBI survivors compared their sense of identity from pre-to-post TBI. Data collection consisted of 2 interviews and participants were compensated with $60 gift cards. Participants (N = 15, Mage = 52.67) were recruited from several language disorder groups. In terms of identity functioning post-brain injury, participant reports of their experiences varied quite a bit from identity loss to a strengthened …

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