Digital Commons Network^™

Optimization Of L-Citrulline Production In Corynebacterium Glutamicum, And The Effect Of The Human Small Intestine Environment, Simran S. Ghulldu

Honors Undergraduate Theses

L-citrulline is a crucial amino acid involved in nitric oxide production, which supports cardiovascular health, physical performance, and intestinal well-being. Nitric oxide deficiency is linked to conditions like hypertension, highlighting the need for efficient L-citrulline production. This study attempts to enhance L-citrulline synthesis in Corynebacterium glutamicum, a bacterium widely used in industrial amino acid production, as well as test a The hypothesis is that overexpressing carAB, which encodes carbamoyl phosphate synthetase, will increase carbamoyl phosphate levels and boost L-citrulline production. Two C. glutamicum strains were used: a wild type and the CRBG strain, which has mutations that promote …

Optimizing Crispri Gene Silencing Of Putative Drug Targets In Mycobacterium Abscessus, Max Ivanov

Honors Undergraduate Theses

Among nontuberculous mycobacteria (NTM), Mycobacterium abscessus (Mab) poses a particular threat to patients with cystic fibrosis and chronic obstructive pulmonary disease due to the lung damage and higher mortality rate it causes. Current treatments involve prolonged multi-antibiotic regimens that are often ineffective, highlighting the need for new drug targets.

The CRISPR Interference (CRISPRi) system uses a deactivated Cas9 protein (dCas9) to enable inducible gene silencing, offering a potential approach to identifying new targets. Genes that lead to a loss of Mab viability when silenced are considered essential, an important attribute of potential drug targets. While CRISPRi has shown …

Synthesis And Characterization Of Multifunctional Cerium Oxide Containing Nanoparticles For Biomedical Applications, Ishaan Patel

Honors Undergraduate Theses

This study presents the synthesis and comprehensive characterization of a novel core-shell nanoparticle composed of a maghemite (γ-Fe₂O₃) core and a europium-doped cerium oxide (EuCNP) shell, developed for potential use in cancer theranostics. Using a co-precipitation method, Fe₂O₃–EuCNP core-shell nanoparticles were synthesized and compared against control samples of CNPs, EuCNPs, and Fe₂O₃. A variety of characterization techniques, including UV-Vis spectroscopy, fluorescence spectroscopy, TEM, XRD, XPS, DLS, TGA, and DSC confirmed the successful synthesis of core-shell architecture and europium doping. Moreover, Fe₂O₃–EuCNPs demonstrating strong colloidal …

Academic Proposals For Combating Authoritarian Populism In The United States: A Review Of The Social Science Literature, Emily A. Padgett

Honors Undergraduate Theses

Throughout American history, the idea of “democracy” has been taught at a base level throughout the school system. While we have been taught what a democracy is, it is rare to understand what a democracy isn’t. There have been threats identified by academics to our democracy throughout different eras in history. Now, in our current political climate, all main threats to democracy have been enacted at once.

This thesis serves as a literature review of a handful of academics and their idea of what the main threats to democracy are. There will be references to different perspectives and schools of …

From Boredom To Purpose: How Self-Concept Can Affect Motivation In The Workplace, Norma I. Cintron

Honors Undergraduate Theses

The present experiment explored whether or not a positive self-concept influences how individuals manage boredom in the workplace. It was hypothesized that individuals with a positive self-concept would cope better with boredom and complete a dull task more accurately. However, these hypotheses were not confirmed, the study found no significant relationship between self-concept and boredom coping, nor between self-concept and task accuracy. In fact, individuals with higher self-concepts were slightly less accurate, though the difference was not statistically significant. Additionally, the study analyzed participants’ written responses to questions about handling boredom using Linguistic Inquiry and Word Count (LIWC) software. The …

Unravelling The Role Of Two-Component Systems In Mycobacterium Abscessus, Andrea C. Molero Perez

Honors Undergraduate Theses

Mycobacterium abscessus (Mab) is an emerging pathogen within the nontuberculous bacteria (NTM) which poses a threat due to its complex multi-drug resistance and opportunistic nature. It is predicted that only 45.6% of patients will have successful treatment, with immunocompromised and cystic fibrosis patients being the most threatened. Moreover, investigating new treatment approaches is key to responding to this public health issue. Two-component systems (TCS) are regulatory pathways that play a pivotal role in bacterial survival and virulence. These systems are composed of a sensor histidine kinase (HK) and cognate response regulator (RR) protein that senses environmental cues and triggers specific …

An Assessment Of U.S. Medical Students’ Self-Reported Knowledge, Attitudes, And Practices In Using Professional Medical Interpreters, Ezinne Okonkwo

Honors Undergraduate Theses

Professional medical interpreters interpret conversations between patients with limited English proficiency (LEP) and physicians. Given the important role professional medical interpreters play for LEP patients, current and future healthcare professionals would benefit from understanding their services and how to utilize them effectively. Research has explored how residents and physicians regard medical interpreters, but few studies have examined medical students' knowledge and perceptions about them. This cross-sectional study investigated medical students' knowledge, attitudes, and practices regarding professional medical interpreters. The sample was comprised of Florida medical students. Participants completed a one-time, quantitative online survey collecting information regarding their medical training, demographics, …

Toward Inclusive Care: Enhancing Lgbtq+ Adolescents’ Experiences In Primary Care, Rutwa Shah

Honors Undergraduate Theses

LGBTQ+ adolescents face significant inequities in healthcare access and health outcomes, yet little is known about how they engage with routine pediatric care, where parental presence and clinician dynamics often influence their ability to access affirming services. While prior research has emphasized the importance of inclusive environments and clinician communication, few studies center the voices of LGBTQ+ youth in clinical settings. This study explored how LGBTQ+ adolescents manage sexual/gender identity disclosure, trust, and communication with primary care clinicians. This study draws on data from The VIBES Study: Viewpoints on Improving Bonds Between Health Experts and Sexual and Gender Minority Youth. …

The Loneliest Number: Implications For Using Single-Item Measures In Regression Analysis, Juliana Reis

Honors Undergraduate Theses

The current study examines the use of single-item measures to assess constructs used by occupational stress researchers. Surveys are fundamental tools for I/O Psychologist practitioners, and multiple-item measures are commonly used to fulfill that purpose. However, long surveys may offer challenges to both administrators and respondents. As an effort to mitigate those challenges, single-item measures have been receiving recognition as a promising alternative to the current psychometric measures due to their benefits, such as reduced cost and higher face validity. We will discuss the previous studies on single-item measures and why it’s relevant to explore its potential by performing a …

Healing Through Art: An Exploration Of Art History Influences On Contemporary Art Therapy For Practices In Oncology Care, Nicole Van

Honors Undergraduate Theses

Art therapy has emerged as a vital practice in oncology, offering patients a means of emotional expression and healing during their treatment journey. This project will explore how integrating art history into therapeutic settings, particularly through virtual classes, enhances the emotional well-being of cancer patients. By examining the impact of engaging with historical artworks, this research aims to illustrate how these artistic narratives can facilitate self-consciousness and foster flexibility in individuals facing significant health challenges. Research indicates that exposure to art can evoke emotion and promote psychological healing, serving as a therapeutic outlet for patients. This study will synthesize therapeutic …

Florida’S Gifted Education Program: Exploring The Nexus Between Giftedness And Choice Of College Major, Sterlin L. Bass

Honors Undergraduate Theses

Florida’s Gifted Education Program (FGEP) is a K-12 educational program in Florida’s public education system through which gifted students are identified and supported through individualized educational plans promoting intellectual development. The intent of this study is to explore the influence Florida’s Gifted Education Program has on the choice of major of a student and mental health outcomes. Current data revolving around different definitions of “giftedness” such as high ACT scores, SAT scores, and GPA, show a connection between negative mental health outcomes produced by the development of perfectionism. FGEP presents challenges in addressing these concerns due to non-standardized curricula across …

Solving The National Security Threat Of The United States Drug Crisis, Anna B. Freehafer

Honors Undergraduate Theses

This thesis analyzes the current drug crisis in the United States with the intention of forming a sound National Security Report and Strategy to equip current and future administrations with the necessary tools and information to adapt to the modern crisis. The number of drug induced and related deaths are rising in the U.S., which arguably is cause for alarm at the federal level. With the country divided on how to properly attack this crisis, which affects hundreds of thousands of lives across the nation, this thesis aims to provide a solution to a drug crisis that is unlike any …

Investigating The Effects Of Binaural Beats On Encoding Efficiency And Working Memory Performance In College Students With Attention-Deficit/Hyperactivity Disorder Traits, Megan Daza

Honors Undergraduate Theses

Binaural beats (BB) have been increasingly explored as a non-invasive cognitive enhancement tool, particularly in populations with neurodevelopmental conditions such as Attention-Deficit/Hyperactivity Disorder (ADHD). This study investigates the effects of beta-frequency binaural beats on encoding efficiency and working memory performance, specifically verbal-spatial working memory, in college students with ADHD traits. Using a 2 (ADHD/Neurotypical) × 2 (Low/High Cognitive Load) mixed ANOVA design, participants will complete an N-back working memory task under baseline, binaural beats, and control (white noise) conditions. Key research questions examine whether binaural beats improve working memory accuracy and reaction time, whether their effects vary across cognitive load …

Generating Negotiations For Iago, Kylee R. Weener

Honors Undergraduate Theses

Negotiation is a complex field that can benefit from introducing artificial intelligence (AI); doing so would benefit researchers as they try to deepen their understanding of human-human and human-agent negotiation. Investigating how large language models (LLMs) can generate negotiation dialogue with emotional context would bring agents closer to acting more human. This study explores how fine-tuning and prompt engineering can achieve this goal and the possibilities for an AI that fills these criteria to be included in the Interactive Arbitration Guide Online platform (IAGO). Doing so will make the negotiation interactions in IAGO feel more complex and natural, allowing researchers …

Quantized Average Agreement Algorithms With Error Correction For Digraphs, Shuaib A. Mughal

Honors Undergraduate Theses

Multi-agent systems have become more and more prevalent as technology increasingly gets integrated into our daily lives. Some of these technological systems are large in size; for example, the smart grid where multiple devices are used to monitor and control different aspects of the energy grid. Another example is a team of autonomous systems deployed for a specific task. When these systems are spatially distributed, an important component of distributed algorithms is the ability for the agents to reach consensus on the global state of the system. Reaching agreement enables the spatially distributed agent make decisions or determine the next …

Polarization On Campus: How Social Media Shapes College Students' Opinions On The Israel Hamas War, Jonah Lynne

Honors Undergraduate Theses

This study examines the impact of social media on the polarization of opinions regarding the Israel-Hamas war, particularly among U.S. college students. Following the outbreak of the war in October 2023, social media platforms such as Facebook, Instagram, X, and TikTok have facilitated the spread of highly partisan narratives, fueling ideological divides. The study highlights how social media contributes to the increase in antisemitic and Islamophobic sentiments, exacerbating societal tensions. Through 25 structured qualitative interviews with college students, the research explores how social media algorithms shape perceptions by reinforcing preexisting beliefs through echo chambers and filter bubbles. Taken as a …

A Signal Processing And Mechanical Design Approach To Understanding Triboelectric And Piezoelectric Nanogenerators’ Output, Nicholas Rose

Honors Undergraduate Theses

Scalable energy harvesters—capable of converting motion into electrical output—provide promising solutions to increasing energy demands. This thesis was inspired by the potential biomedical applications of piezoelectric nanogenerators (PENG) and triboelectric nanogenerators (TENG). In theory, these devices could convert mechanical energy from the body into usable electricity for self-powered electronics such as pacemakers or cochlear implants. In line with this goal, this project worked to design a sustainable and biocompatible PENG; however, early devices produced inconsistent voltage. These output inconsistencies motivated an exploration of device reproducibility, but characterizing piezoelectric output signals is a particular challenge in the field. Subtle to significant …

Threading The Needle: Chinese American Adoptees And The In-Between, Annalee Johnson

Honors Undergraduate Theses

Threading the Needle is a short documentary that investigates the relationships between Chinese American adoptees, their families, and their heritage. The film features two primary participants, Mia Nails and Annalee “AJ” Johnson as they reflect on their Asian American identity, experiences with racism, and their struggles with cultural estrangement. The similarities and differences in their perspectives shed light on both the wonderful and the heartbreaking circumstances of adoption. The contemporary value of the film lies in how it challenges popular representations of the Asian American experience: Though in recent years, Asian American media has become more present in popular culture, …

Mental Illness Identity And Social Media Use In Generation Z, Tobey Smith

Honors Undergraduate Theses

The present study investigated factors that predict a high degree of mental illness identity among Generation Z college students. Specifically, the author aimed to evaluate social media use and other psychosocial factors, including social isolation, self-esteem, well-being, discrimination, and attitude toward recovery. Two-hundred and seventeen participants were recruited using SONA and social media. Participants completed scales to measure the variables of interest: Illness Identity Questionnaire - Mental Health, Rosenberg Self-Esteem Scale, Warwick-Edinburgh Mental Well-being Scale, Hope and Coping in Recovery Scale, Cornwell Perceived Isolation Scale, Stigma Scale, Social Media Use Scale, and a set of demographic questions. Pearson bivariate correlations, …

Cloud Condensation Nuclei Activity Of Fresh And Aged Phenolic Acid Aerosol Particles, Emily A. Nortmann

Honors Undergraduate Theses

In recent years, the incidence of wildfires has considerably increased, with fire seasons starting earlier and ending later than usual due to changes in snowpack, precipitation, and temperature, which are attributed in part to climate change. Wildfires are responsible for the emission of a variety of gases and organic aerosol particles in the atmosphere with profound impacts on air quality, visibility, and human health. The aerosol particles produced by wildfires can contribute to climate change by scattering or absorbing solar radiation, affecting the radiative balance of the planet through cooling or warming effects, or by acting as cloud condensation nuclei …

Improving Safe And Effective Management Of Pain At Home, Alayna V. Olivarez

Honors Undergraduate Theses

Pain is the most common clinical symptom in individuals with a cancer diagnosis. Additionally, home is the preferred place for cancer care which introduces numerous challenges for cancer pain management. The primary purpose of this literature review is to identify support interventions to enhance pain control, prevent exacerbations in pain, and optimize quality of life in individuals with cancer transitioning from the acute care setting to home. The secondary purpose of this review is to analyze patient-specific barriers influencing self-efficacy of pain management and overall health outcomes in the target population. A systematic literature search was conducted using CINAHL, EBSCOhost, …

Navigating Online Dating: Exploring The Intersection Of Attachment Styles, Parental Attachments, And Sociosexuality In Online Dating Among College Students, Jensley Velez-Lozada

Honors Undergraduate Theses

The aim of this thesis is to explore the connection between attachment styles, parental attachment, and sociosexuality as predictors of online dating attitudes among college students. As society navigates this new digital era of online dating, how does it continue to transform young adults as they form romantic and sexual connections? It becomes increasingly important to understand the psychological mechanisms that influence these behaviors. This study examined how anxious and avoidant attachment styles, parental attachment, and sociosexuality may have contributed to online hookup attempts and outcomes behaviors. It also examined how these variables interacted and influenced both the likelihood of …

The Impact Of Divorce Proceedings On Victims Of Domestic Violence, Quinn G. Di Ienno

Honors Undergraduate Theses

Divorce often signifies the end of conflict in relationships that individuals no longer wish to continue. However, the impact of divorce on victims of intimate partner violence (IPV) is a topic that remains underexplored. This research investigates the extent to which individuals navigating divorce proceedings are victims of IPV and aims to illuminate their experiences within the legal system. The study delves into various forms of abuse, including physical, emotional, and financial, while also addressing the challenges victims face in seeking assistance. Employing a mixed-methods research design, this study comprises a comprehensive literature review and an online survey targeting those …

How Does The Modern Supreme Court Treat The Idea Of Retribution In The Context Of Capital Punishment?, Paige Forsberg

Honors Undergraduate Theses

This thesis explores the modern U.S. Supreme Court's treatment of retribution in the context of capital punishment, analyzing how justices have framed and justified the death penalty as a form of justice. Through the examination of key Supreme Court rulings and legal arguments, this study evaluates the evolving role of retribution in the Court’s decisions on death penalty cases, highlighting how judicial reasoning has shifted over time in response to legal, philosophical, and societal developments.

Retribution, long considered one of the primary justifications for capital punishment, is examined through a nuanced lens in this study. While historically viewed as a …

Behavior Analysis Of Simple And Complex Workloads, Davi D. Dantas

Honors Undergraduate Theses

Complex tasks have evolved rapidly in recent times due to tremendous advancements in computational power and data availability. With the ever-increasing presence of complex applications, this paper attempts to distinguish between complex and simple applications. This paper explored side-channel analysis as a method to differentiate complex workloads from simple workloads by monitoring system-level metrics such as power consumption, cache behavior, and memory accesses. By leveraging side-channel effects such as power analysis and memory access, this study seeks to establish unique hardware signatures for complex workloads. Using tools such as Intel Pin, the data will be collected from complex and simple …

Stem Vs. Non-Stem Students’ Stimulant Misuse For Academic Advantages, Camille H. Allie

Honors Undergraduate Theses

This study aimed to explore the relationship between academic discipline, caffeine consumption, reported perception of stimulant misuse behaviors, and reported academic stress at the University of Central Florida. Participants were categorized as either STEM or non-STEM majors and reported whether they had misused stimulants in the past 12 months and their daily average caffeine consumption. Due to the low number of participants who reported stimulant misuse, caffeine consumption was incorporated, grouping participants as either “above median” caffeine consumption or “below median” caffeine consumption. Two 2 (Caffeine Consumption: High vs. Low) x 2 (Major: STEM vs. Non-STEM) between-subjects ANOVAs were conducted …

An Exploration Of Preservice Teachers' Perspectives On Elementary Writing Instruction, Railynn E. Baumgardt

Honors Undergraduate Theses

Writing instruction is frequently overshadowed by a greater emphasis on reading and mathematics in elementary education, resulting in preservice teachers (PSTs) often feeling underprepared and lacking confidence to teach writing effectively. This undergraduate thesis explores the perspectives of junior and senior elementary education majors at the University of Central Florida enrolled in the course Teaching Language Arts for the Elementary Classroom (LAE 4314). Using an anonymous online survey, this study investigated 38 PSTs as writers themselves, their beliefs about writing instruction, their preparedness to teach writing, and the impact of the methods course on their readiness to teach writing. Results …

The Truth And Their Versions: Florida Lawmakers And Academic Freedom Across K-12 And Higher Education, Kassandra Faylun

Honors Undergraduate Theses

Florida’s HB 7 and SB 266, enacted July 1, 2022, and July 1, 2023, respectively. HB 7 controls how certain race-related concepts, like critical race theory, are taught in K-12 classrooms and higher education. SB 266, apart from prohibiting expenditures for DEI programs, provides new requirements for general education core course curricula, including the disallowing of teaching identity politics and barring any classes that are “based on theories that systemic racism, sexism, oppression, and privilege are inherent in the institutions of the United States and were created to maintain social, political, and economic inequities.” Both HB 7 and SB 266 …

The Effects Of School-Based Menstruation Education Programs On Anxiety And Self-Efficacy In Adolescent Girls: A Systematic Review, Hannah C. Hart

Honors Undergraduate Theses

A significant global knowledge gap exists for adolescent girls regarding what constitutes a healthy menstrual cycle, proper menstrual hygiene practices, and the implications of reproductive maturity that is ushered in by menarche. This limited understanding can lead to poor health outcomes and the development of negative sentiments and beliefs surrounding the normal experience of menstruation.

This systematic review aims to comprehensively investigate the current state of research regarding the effects of school-based, formal menstruation education programs on adolescent girls, particularly the effects on anxiety and self-efficacy related to the management of menstruation. Furthermore, this work aims to take a stance …

Role Of C4 Resources In Isotopic Variability In Diet Among Children From Kellis 2 Cemetery, Dakhleh Oasis, Egypt, Faith R. Hendrix

Honors Undergraduate Theses

Using stable carbon isotope analysis, this study investigates dietary diversity in children buried at the Kellis 2 Cemetery (c. AD 50–450) in Egypt's Dakhleh Oasis. From the analysis of δ¹³C isotope values in hair keratin and bone collagen, the study reconstructs short-term and long-term dietary signals in juvenile and adult subjects. The aim is to clarify the role of C₄ plants—particularly millet—in weaning and childhood diets in a Romano-Christian Egyptian village context. A total of 631 segmented hair and 54 bone collagen samples were analyzed from 127 juveniles and 97 adults. Juvenile individuals (i.e., under 15 years biological age) showed …