Digital Commons Network^™

Go Ahead, Daytona, John Hughes

Electronic Theses and Dissertations

Go Ahead, Daytona is a collection of essays meant to explore the experiences and lessons learned through law enforcement. It juxtaposes hope with cynicism and encourages the reader to explore his or her own biases through the lens of a narrator believing police work is something to be lived down, rather than up. The essays depict struggles with hypocrisy, sex, homelessness, violence, moral ambiguity, and self-awareness.

The Clockman Movement, Allison Martin

Electronic Theses and Dissertations

As a genre of Neo-Victorian fiction, Steampunk is largely identified by Victorian aesthetics and technology centering on clockwork and steam power. The novel The Clockman Movement seeks to emphasize the "punk" in "steampunk" by exploring the social concerns of colonialism, including sexism, racism, and classism, while embracing the more fantastic and entertaining aspects of steampunk. Before all other labels—Nordlunder, daughter, woman—Eve Traugott is a machinist. Or she would be, if one of the machinists in the capital would hire her as an apprentice. She thought it would be simple to find a machinist willing to take a chance on her …

The Role Of Occupational Branding In The Professionalization Of Technical Communication, Chelsea Thomas

Electronic Theses and Dissertations

This study investigates the relationship between professional identity and professional status by exploring the quest for professionalization within technical communication. An established professional identity is crucial to an occupation's professionalization process, as it enables members of a given field to create a common sense of being and facilitates a recognizable personal and collective identity. Such recognition is vital to an occupation's rise to professional status, as it creates a distilled image of the ideal practitioner for outsiders and forms the basis upon which claims of expertise may be made. By constructing the meaning surrounding their profession, members are able to …

The Gasoline Tree, Brianne Manning

Electronic Theses and Dissertations

In exploration of Millennial anxieties and the power of dreaming, The Gasoline Tree imagines a soundtrack for the revelations, defeats, and curiosities of leaving childhood behind. This is a collection of 40 poems that examines eating disorders, gender roles, physical abuse, sex, infidelity, loneliness, and the fear of losing one's parents. This collection also contemplates the brutalities and muted delights of what drives us all: love, in all of its forms. "The Gasoline Tree," "Wolf of Chocorua," and many other poems construct New England landscapes that pay homage to the pastoral uniqueness of Maxine Kumin and Galway Kinnell, while poems …

Unseen America, Jeffrey Shuster

Electronic Theses and Dissertations

Unseen America is a glimpse into the lives of what American society considers to be low status men. "Kumbaya" involves a Cub Scout dealing with the fallout from a neglectful father and an alcoholic mother. "Devil's Tower" is about an overweight boy trying to prove himself in front of his peers. In "True Patriots," we see two displaced working class men forced to come to terms with an America that doesn't belong to them anymore or need them anymore. "Zippo Heart" deals with a recently divorced young woman spurring on the advances of a loser coworker while dealing with her …

The Missing Middle: Understanding The Effects Of Social Enterprise On Nonprofit Performance, Angela White-Jones

Electronic Theses and Dissertations

The 2008 financial recession has seen increased poverty, job loss, and homelessness as well as decreased spending in health care, education, sanitation, and housing. These factors can lead to tensions across a number of sectors and underscore the need for innovation in for-profit, nonprofit and government organizations. One area of innovation in the nonprofit sector to supplement revenues is by adding social enterprise activity. Social enterprise is the pursuit of earned income activities for an organization that is driven by a community mission or value. Because financial and social problems are becoming increasingly intertwined, this study seeks to understand the …

The Role Of The Intermembrane Domain Of Mulan In Mitophagy And Cell Death, Jared M. Herbert

Honors Undergraduate Theses

Mulan is an E3 ubiquitin ligase and an E3 SUMO ligase embedded in the outer mitochondrial membrane. Mulan plays a major role in various cell processes including cell growth, mitophagy, apoptosis, and mitochondrial dynamics. In addition, its deregulation is involved in the development and progression of several human disorders such as neurodegeneration and heart disease. There are two main discernible domains in Mulan: a large cytoplasmic domain that encodes the RING-finger motif and carries out the catalytic activity of the protein; the second domain of Mulan is exposed to the intermembrane space of mitochondria, and its function remains unknown. This …

Microfinancing In Punjab, Pakistan: How Effective Are Microloans On The Very Poor?, Kamila N. Pervaiz

Honors Undergraduate Theses

Microfinance has been around since the 1970s to help alleviate financial burden for the underprivileged by issuing microloans and credit programs to promote business activity. Microfinance institutions have helped multiple people around the world start their own businesses and become entrepreneurs through the process of microloans and offering credit at lower rates. The purpose of this paper is to explore the impact of microloan on the very poor low income borrowers in Punjab, Pakistan. Although this study was not conducted, the research is based on empirical investigation of interviews taken around the area.

American Agribusiness & Biotechnology: A New Era Of Farming, Nicole M. Ryan

Honors Undergraduate Theses

In the past fifty years there has been an incredible amount of change made to the agrarian system of the United States. New discoveries in the realm of biotechnology led to the adoption of genetically modified organisms (GMOs) in agriculture, and transformed the industry. Due to regulatory policies set during the nineteen-eighties this technology was able to benefit from widespread commercialization.

Today, we see the effects of this approach and are entering into a highly volatile political climate in regard to GMOs. This paper aims to provide an analysis of the regulatory system in place and the discrepancies that exist …

Theodore Pratt And The Fiction Of Nostalgia, Maurice O'Sullivan

The Marjorie Kinnan Rawlings Journal of Florida Literature

No abstract provided.

Vol Xxiv (2016)

The Marjorie Kinnan Rawlings Journal of Florida Literature

No abstract provided.

"Who Owns Cross Creek?" Rawlings And The Cracker Ethics Of Nature, Robert Bowman

The Marjorie Kinnan Rawlings Journal of Florida Literature

No abstract provided.

"The Metamorphosis Of Live Creatures": Animal Ethics In Rawlings's The Yearling, Haili Alcorn

The Marjorie Kinnan Rawlings Journal of Florida Literature

No abstract provided.

Novel Photodynamic Cancer Therapy Agent And Biochemical Phosphate Sensor Based On Nanomaterials, Alaa Fadhel

Electronic Theses and Dissertations

Biochemical research and clinical studies have revolutionized the field of medicine in both diagnosis and therapy. Researchers in the field of biochemistry and biotechnology are using nanomaterials in different applications to develop devices and materials that offer benefits to both patients and the health care industry. These include biochemical sensors, enzyme encapsulation, biomarkers, and drug delivery improvements for the treatment of cancer. This dissertation focuses on investigating two biochemical aspects using nanomaterials; namely therapy and clinical diagnosis. For therapy purposes, Silica nanoparticles were used as drug delivery system to develop a new photodynamic cancer therapy agent photo-acid generator (PAG) that …

Interpreters Of Nature: Marjorie Kinnan Rawlings, Frank Lloyd Wright, And The "Sense Of Place", H Alexander Rich

The Marjorie Kinnan Rawlings Journal of Florida Literature

No abstract provided.

Identification Of The Effects Of Diabetes Mellitus On The Brain, Tryphina A. Mikhail

Honors Undergraduate Theses

As more studies accumulate on the impact of diabetes mellitus on the central nervous system, they resound with the same conclusion - diabetes has a detrimental effect on cognition regardless of the presence of comorbidities. Less consistent however, are the specific mental processes wherein these declines are noticeable, and the structural changes that accompany these reductions in mental capacity. From global atrophy to changes in the volume of gray and white matter, to conflicting results regarding the effects of hypo- and hyperglycemic states on the development of the hippocampus, the studies display a variety of results. The goal of this …

A Mathematical Model For Feral Cat Ecology With Application To Disease., Jeff Sharpe

Electronic Theses and Dissertations

We formulate and analyze a mathematical model for feral cats living in an isolated colony. The model contains compartments for kittens, adult females and adult males. Kittens are born at a rate proportional to the population of adult females and mature at equal rates into adult females and adult males. Adults compete with each other in a manner analogous to Lotka-Volterra competition. This competition comes in four forms, classified by gender. Native house cats, and their effects are also considered, including additional competition and abandonment into the feral population. Control measures are also modeled in the form of per-capita removal …

Causal Factors Of Cryptorchidism And Endocrine Disurpting Chemicals Such As Prenatal Maternal Cigarette Smoke: A Narrative Review, Andrew R. Morrissey

Honors Undergraduate Theses

Cryptorchidism is a male congenital disorder with an unspecified, multifactorial etiology. This review evaluated the strength of select factors in the development of cryptorchidism to better understand its etiology. The strength of relationship between factors and their respective functions during testicular descent was evaluated. Factors evaluated in the causal pathway include the signaling mechanisms Desert Hedgehog (DHH), Insulin-like Hormone 3 (INSL3) and Platelet-Derived Growth Factor (PDGF), as well as sex hormone regulation (androgen: estrogen ratio, aromatase expression). Articles supporting a factor in testicular descent were evaluated and scored. These scores were summed to create the “Step Score” for each step …

Aeromonas Hydrophila In Amphibians: Harmless Bystander Or Opportunistic Pathogen, Zachary P. Rivas

Honors Undergraduate Theses

For several decades amphibian populations have been declining. Historically, the bacterium A. hydrophila (Ah) was hypothesized to be the causal factor in amphibian disease and population declines. However, with the discovery of a chytrid fungus, Batrachochytrium dendrobatidis (Bd) in 1998, which was identified on the skin of amphibians during documented mortality events, Ah research became of minor interest as focus shifted to Bd. Recent studies into the immunocompromising abilities of Bd, however, have opened new questions about its relationship with Ah and their combined effects on a host.

In this study, I explore the …

Cardiac Consequences Of Selective Adrenergic Cell Ablation In Mice, Lahari Tumuluri

Honors Undergraduate Theses

Phenylethanolamine-N-methyltransferase (Pnmt), is the enzyme that catalyzes the conversion of noradrenaline to adrenaline. It has been found in the embryonic heart and in certain adult heart cells, including intrinsic cardiac adrenergic cells, intracardiac neurons, and cardiomyocytes, but their physiological role in the heart is not well understood. To determine the function of Pnmt-expressing cells in the developing heart, a novel genetically-targeted mouse model that causes selective cellular suicide of Pnmt-expressing cells was created by mating Pnmt-Cre Recombinase knock-in mice (Pnmt^Cre/Cre) with ROSA26-eGFP-DTA (R26R^+/DTA). The “cellular suicide” allele is the Diptheria Toxin A (DTA) gene …

Intramuscular Tnf-Alpha Signaling In Response To Resistance Exercise And Recovery In Untrained Males., Jeremy Townsend

Electronic Theses and Dissertations

INTRODUCTION: The nuclear factor kappa B (NF-κβ) signaling cascade is responsible for mediating stress-activated catabolic effects of Tumor Necrosis Factor Alpha (TNF-α) downstream of the TNF receptor (TNFR1). NF-κβ transcription factor remains inhibited in the cytosol of the muscle and can be stimulated for translocation and transcription by a variety of external stimuli, most notably by pro-inflammatory cytokines and oxidative stress. Nevertheless, currently there is a gap in the literature with regard to the time course effect of NF-κβ signaling following acute resistance exercise in humans. PURPOSE: To observe the effects of an acute lower-body resistance exercise protocol and subsequent …

Dining With The Cyborgs: Disembodied Consumption And The Rhetoric Of Food Media In The Digital Age, Maggie Cotto

Electronic Theses and Dissertations

This project explores digital media productions based specifically on food and cooking in order to demonstrate that new communication technologies are increasingly incorporating all five of the bodily senses. In doing so, they contribute significantly to the emergence of new ideological apparatuses appropriate for a global community. These apparatuses – including the formation of a posthumanist subject, the use of technology to support embodied cognition, and the establishment of entertainment as an ideological institution – have become the harbingers of a rhetorical evolution. Based on the work of Gregory Ulmer, along with Jacques Derrida, N. Katherine Hayles, Donna Haraway, and …

Recognizing Pain Using Novel Simulation Technology, Justin C. Grace

Honors Undergraduate Theses

Effective pain management and time to treatment is essential in patient care. Despite scientific evidence supporting the need to treat pain and an emphasis on addressing pain as a priority, pain management continues to be an unresolved issue. As a member of the health care team, nurses are integral to optimal pain management. Currently, nursing schools have limited innovative or alternative methods for teaching pain assessment and management. Simulation in nursing education provides a unique opportunity to expose students to realistic patient situations and allow them to learn and make mistakes without causing harm. However, modern low- and high-fidelity simulation …

Vitamin D Clinical Relevance In The Recovery From Traumatic Brain Injury Among The Military Population, Yuisa M. Colón

Honors Undergraduate Theses

Background: Traumatic brain injury (TBI) still remains a difficult disorder to treat. TBI has been associated to chronic neuroinflammation and a high risk for neurodegenerative disorders. Since 2001 between ten to twenty percent of all deployed military members have suffered a combat-related TBI. Nearly twenty to thirty percent of those will experience chronic cognitive, behavioral and somatic symptoms after suffering a TBI.
Methods: The objective of this review is to evaluate current literature examining vitamin D as a neurosteroid with protective properties and its clinical relevance after traumatic brain injury. Vitamin D is known to participate in neurobiological …

Vo-Ohpic Treatment Reduces Cardiac Remodeling In Doxorubicin-Induced Cardiomyopathy, Taylor Johnson

Electronic Theses and Dissertations

Doxorubicin (Doxo) is one of multiple anthracycline drugs used to effectively treat various forms of cancer. Unfortunately, Doxo treatment, as a side effect, induces cardiomyopathy and subsequent heart failure. We have previously demonstrated that transplanted embryonic stem (ES) cells and their conditioned medium (CM) modulate the PTEN pathway and reduce apoptosis, fibrosis and hypertrophy in a Doxo induced cardiomyopathy (DIC) model. However, mechanisms of inhibited apoptosis mediated through PTEN pathway are completely unknown. Therefore, we used VO-OHpic (VO), a potent PTEN inhibitor to understand the mechanism of apoptosis as well as its effect on cardiac remodeling in DIC. Animals were …

The Role Of Type-I Interferon In Limiting Spread And Killing Of An Oncolytic Rna Virus In Prostate Cells, Kritika Kedarinath

Electronic Theses and Dissertations

Prostate cancer is the second most prevalent cancer amongst men and there is an urgent need to address viable therapeutic options for its treatment. Development of viruses which target and kill cancer cells has gained momentum due to the first FDA approved oncolytic virus for treating human cancer patients. Our previous work with the RNA virus, Parainfluenza Virus 5 (PIV5), has led to the generation of mutants that are potential candidates for oncolytic viruses: 1) the hyperfusogenic (P/V/F) mutant has a mutated P/V and fusion gene which activates anti-viral responses and causes massive cell-cell fusion respectively, and 2) the Leader …

Malondialdehyde (Mda) And Glutathione Peroxidase (Gpx) Are Elevated In Crohns Disease-Associated With Mycobacterium Avium Subspecies Paratuberculosis (Map), Ahmad Qasem

Electronic Theses and Dissertations

Inflamed tissue in Crohn’s disease (CD) are continuously producing toxic oxygen metabolites leading to cellular injury and apoptosis. Here, we are evaluating the role of Mycobacterium avium subspecies paratuberculosis (MAP) in oxidative stress in CD by evaluation of lipid peroxidation and antioxidant defense activity. Specifically, we measured malondialdehyde (MDA) level and selenium-dependent glutathione peroxidase (GPx) activity in the plasma from patients and cattle infected with MAP. The level of MAP antibodies in bovine sera was determined by IDEXX kit whereas detection of MAP DNA was performed by IS900-based nPCR. A total of 42 cattle (21 infected with MAP and 21 …

Informational Efficiency And The Reaction To Terrorism: A Financial Perspective, Nicholas Roland

Honors Undergraduate Theses

The purpose of this study is to measure the message terror organizations hope to convey using the financial markets as a proxy of measurement to determine patterns within the marketplace and the effects on the terrorists’ ability to deliver a desired message due to the increased use of digital devices and access to instantaneous news, seen over the past decade. Using death count, geographic location, and event type, this study identified 109 attacks between 1985 and 2015 to be analyzed against 5 market indices and 5 securities. Measuring the effects within a 10-day sample window from the time of the …

Adolescent Mothers’ Implementation Of Strategies To Enhance Their Children’S Early Language And Emergent Literacy Skills, Meredith C. Canty

Honors Undergraduate Theses

Previous studies have examined how the language skills of children with adolescent mothers differs from children of older mothers. However, there is limited information on what specific strategies adolescent mothers utilize to increase early language and emergent literacy skills in their children. The aim of the present study is to examine adolescent mothers’ use of strategies to increase the early language and emergent literacy skills of their young children. A sample of 14 adolescent mothers enrolled in a teen parenting program were surveyed on their use of common strategies that are shown to facilitate early development of language and literacy …

Pharmacogenomic Management Of Familial Hypercholesterolemia: An Integrative Review Of The Literature, Brian V. Skibo

Honors Undergraduate Theses

The purpose of this thesis is to examine familial hypercholesterolemia (FH) and emerging pharmacogenomics therapies that propose to lower serum low density lipid (LDL) levels. The search of various data bases resulted in nine research articles being selected for review. Syntheses of the articles suggest emerging phamacogenomic drug therapy can improve treatment outcomes for individuals with a diagnosis of FH. The Human Genome Project (HGP) has had far reaching applications for genomic technologies and pharmacagenomic interventions, tailored to human conditions associated with select genomic traits. Synthesis of nine research articles demonstrate that little is known on the topic and reveals …