Digital Commons Network^™

Research And Innovation Update, July 8, 2026, Office Of The Vice President For Research And Innovation

Office of Research, Economic Engagement and Outreach

No abstract provided.

Tgf-Β Drives The Conversion Of Conventional Nk Cells Into Uterine Tissue-Resident Nk Cells To Support Murine Pregnancy, Josselyn D Barahona, Liping Yang, D Michael Nelson, Wayne M Yokoyama

2020-Current year OA Pubs

Tissue microenvironments shape lymphocyte differentiation to align immune function with local physiological demands. Uterine natural killer (NK) cells are critical for reproductive success, yet the molecular cues in the uterus that instruct their specialized identities remain incompletely understood. Here, we identify a TGF-β-dependent differentiation pathway by which circulating conventional NK cells convert into uterine tissue-resident NK cells during murine pregnancy. Loss of TGF-β receptor II expression in

Gene Dosage Differences And Non-Linear Impacts On Complex Traits., Craig Smail

Manuscripts, Articles, Book Chapters and Other Papers

Large differences in gene dosage are usually associated with opposite phenotypic effects but show a bias toward one direction in aggregate genome wide. Milind et al. suggest that this is explained by differences in regulatory mechanisms by which genes influence phenotypes and by the increased selective pressures acting on a subset of genes.

Standar Ganti Rugi Materil Dalam Kasus Perbuatan Melawan Hukum Pada Hewan Di Indonesia Berdasarkan Kasus Blackout Pln Pada Putusan Pengadilan Negeri Nomor 09/Pdt.G.S/2019/Pn Jkt Slt, Nathania Debora Siagian, Rosa Agustina

Lex Patrimonium

This study examines the standard of material compensation for pet deaths due to unlawful acts in Indonesian law, using a case study of District Court Decision No. 09/PDT.G.S/2019/PN JKT Sel, which rejected a claim for the death of four koi fish due to a power outage by PLN. Through doctrinal legal research with case and comparative law approaches, this study finds that Indonesian law still categorizes animals as movable objects, limiting compensation to provable economic loss, without considering emotional value. The court ruled that the power outage was not an unlawful act due to lack of fault, thus limiting PLN’s …

Advances In Gene Editing Strategies For Viral Disease Resistance In Pigs: Knock-Out, Knock-In, And Overexpression Approaches, Zhao Namula, Takeshige Otoi, Aya Nakai, Megumi Nagahara, Maki Hirata, Fuminori Tanihara

The Thai Journal of Veterinary Medicine

Highly contagious viral pathogens—such as porcine reproductive and respiratory syndrome, classical swine fever, and African swine fever—continue to pose serious threats to the swine industry and cause major global economic losses. Conventional disease control approaches, such as vaccination and biosecurity, are limited by viral heterogeneity and immune escape mechanisms. Gene editing technologies, most notably the CRISPR/Cas9 system, offer an innovative means of introducing innate viral disease resistance or resilience in pigs. The continuous improvement of these tools can provide a sustainable strategy to enhance animal welfare and global food security and reduce reliance on traditional control measures. This review provides …

Foreword, Adam Fortier-Brown

Maine Law Review

Access to legal services in America has emerged as one of the most pressing structural challenges facing the legal community. As attorneys increasingly concentrate in metropolitan areas, large areas are left with few practicing attorneys and challenging prospects of attracting many more. The consequences of this challenge reach across nearly every aspect of life in these communities—from housing and family stability, to starting or winding down businesses, and critically, to the constitutional guarantees that attach when someone is charged with a crime. Yet, these challenges have also generated a period of genuine creativity and collaboration between communities and different institutions. …

Rurality And Redistricting: California's Proposition 50, Rural Identity, And Democratic Legitimacy, Lisa R. Pruitt

Maine Law Review

When California voters embraced mid-decade congressional redistricting in 2025, the greatest media attention landed on the state’s First Congressional District, CA-01. It is residents of that district who are likely to feel the consequences of the new maps most profoundly. In the form established by the California Citizens Redistricting Commission in 2021, CA-01 occupied more than 26,000 square miles in the state’s northeastern corner. The district included a number of inland counties stretching from Modoc, tucked into the corner formed by the Oregon and Nevada state lines, to Colusa, in the Great Central Valley. The cluster of ten counties—hereinafter “old …

Should I Stay Or Should I Go? The National Flood Insurance Program And Where We Go When The Next Storm Hits, Kevin Fitzpatrick

Ocean and Coastal Law Journal

This article argues that what makes the difference in success between these two regimes is how strictly the scientific advice underlying catch limits the advice is adhered to, and the influences allowed unto decisionmakers in the catch limit negotiation process. Whereas the United States uses the scientific advice about the MSY as a strict upper limit in determining annual catch limits, the EU does not. This allows stakeholders in the EU’s CFP governance, in particular fishing industry actors, to influence regulators to raise TACs above adequately precautionary levels in the name of “balancing” sustainable fishing with short-term economic interests. The …

"Tac-Ing" On Coherence: Achieving Sustainable Baltic Sea Fisheries Management By Hooking Precautionary Science And Greater Transparency In Eu Total Catch Negotiations, Patrick Seroogy

Ocean and Coastal Law Journal

This article argues that what makes the difference in success between these two regimes is how strictly the scientific advice underlying catch limits the advice is adhered to, and the influences allowed unto decisionmakers in the catch limit negotiation process. Whereas the United States uses the scientific advice about the MSY as a strict upper limit in determining annual catch limits, the EU does not. This allows stakeholders in the EU’s CFP governance, in particular fishing industry actors, to influence regulators to raise TACs above adequately precautionary levels in the name of “balancing” sustainable fishing with short-term economic interests. The …

Alaska's Hidden Gems: Advocating For The Protection Of Deep-Sea Corals, Both In The Courtroom And Beyond, Lauren Beizer

Ocean and Coastal Law Journal

Coral reefs are ecologically, financially, and aesthetically one of the world’s greatest resources. Off the coast of Alaska, many unique species of deep-sea cold-water corals exist and provide various public health benefits, contribute vital ecosystem functions to their surrounding environment, and serve as economic tourist attractions. Alaska’s corals reefs are exceedingly valuable to the earth due to their overall ecological value. However, these unique coral species significantly lack state and federal protections–which have recently been under consideration in several lawsuits at the federal level. American Oceans Campaign v. Daley and Oceana, Inc. v. National Marine Fisheries Service et al., are …

Editor's Page, Art Mcphee

Witness

No abstract provided.

Evaluation Of Diclazuril And Amprolium Against Eimeria Spp. In Vietnamese Broilers: Implications For Intestinal Integrity And Claudin Gene Expression, Nguyen Thi Hoa, Pham Hoang Son Hung, Le Dinh Phung, Le Duc Thao, Nguyen Van Chao, Tran Thi Na, Tran Cao My Linh, Ho Thi Dung

The Thai Journal of Veterinary Medicine

This study aimed to assess the resistance status of Eimeria spp. in Vietnam to diclazuril and amprolium and to evaluate their effects on intestinal recovery following infection. One hundred 12-day-old chicks were randomly allotted to four groups: a non-infected negative control (NC), an infected untreated as positive control (PC), an infected group treated with diclazuril (DI), and an infected group treated with amprolium (AM). At day 14, chicks from all groups except NC were orally challenged with 2 × 10⁴ sporulated Eimeria oocysts (E. tenella, E. maxima, E. acervulina, and E. mitis). On day 7 …

Conservation Education And The Cultivation Of Environmental Responsibility: Case Studies From Sri Lanka, Jody Miller, Pasindu Dilshan Abegunawardhana

International Journal on Responsibility

Conservation education encompasses effective pedagogical practices that enhance knowledge of the environment and foster responsible environmental actions. In addition to building an informed citizenry, conservation education is shaped by theoretical stances about the components necessary to cultivate environmental responsibility among participants and their communities. Highlighting three of our own conservation education projects in Sri Lanka as case studies, we draw from research and debates about environmental responsibility to illustrate the incorporation of environmental engagement and responsibility into these efforts, and the difficulties that arise in doing so. Sri Lanka is one of eight global biodiversity hotspots prioritized for conservation intervention. …

Olli Fall 2026 Catalog, Toniann Leavitt

Osher Lifelong Learning Institute

No abstract provided.

Beyond 72 Hours: A Retrospective Evaluation Of Factors Associated With Delayed Surgical Stabilization Of Rib Fractures., Alexis A Schweibinz, Clarisse Solis, Anna Michaud, John Dillis, Katherine A Graham, William B Devoe

OhioHealth Research Institute Articles

BACKGROUND: Surgical stabilization of rib fractures (SSRF) is recognized as a key intervention in reducing morbidity among patients with multiple displaced rib fractures or flail chest. Early SSRF, typically within 72 hours of admission, has been associated with improved outcomes. The factors contributing to delayed stabilization, defined as 72 hours or greater following admission, remain unclear.

METHODS: A retrospective cohort study was performed, evaluating 492 trauma patients who underwent SSRF at a level II trauma center. Patient demographics, injury characteristics, and associated injuries were analyzed to identify factors associated with delayed SSRF. Groups were defined as early (≤72 hours) and …

Hemidiaphragmatic Segmental Zoster Paresis, Terrence Sanvictores, Johnson Ukken

School of Medicine Faculty Research

The reactivation of latent varicella-zoster virus within infected neurons can lead to common clinical manifestations, including rash, acute neuritis, post-herpetic neuralgia, herpes zoster ophthalmicus, and Ramsay–Hunt syndrome. Segmental zoster paresis is an unusual neurologic complication of shingles that is defined by focal asymmetric motor weakness in the myotome corresponding to skin lesions of the dermatome. This case is a presentation of a patient who developed chronic hypoxia and severe atelectasis attributed to right-sided phrenic nerve paralysis secondary to herpes zoster infection.

Depaul Digest

DePaul Magazine

James Bort, assistant professor at the Driehaus College of Business, levels the playing field for underdog entrepreneurs. Arieahn Matamonasa Bennett, associate professor at the School of Continuing and Professional Studies, helps connect to the natural world through equine-assisted therapy. Plus, alumni pitch in during Vincentian Service Day and the latest news from DePaul's 10 colleges and schools, from music education students teaching youth to law students engaging in international human rights work.

Class Notes

DePaul Magazine

From promotions to performances, see the latest accomplishments by DePaul alumni across class years and generations. Plus, read alumni spotlight profiles of Derrick M. Robinson Jr. (SCPS '11), who battles bullying through sneakers donations, and Alessandra Swanson (JD '09), a first-generation alumna who rose to partner at a prominent national law firm.

Extrafloral Nectaries In Woody Plants: Toward An Integrated Framework For Ant-Mediated Plant Defense, Fangming Liu, Qifei Cai, Victor Busov, Zhen Liu

Michigan Tech Publications

Extrafloral nectaries (EFNs)—secretory structures that recruit predatory arthropods as indirect defenders against herbivory—have been studied almost exclusively in herbaceous systems, leaving a critical gap in our understanding of plant defense in woody plants. In trees, secondary growth, ontogenetic regulation, and seasonal phenology generate structural and temporal heterogeneity in EFN expression poorly captured by existing frameworks. We synthesize evidence across structural, chemical, and functional dimensions of EFN biology to develop an integrated framework for perennial trees. Our analysis suggests that methodological limitations in EFN detection likely bias the current chemical record of woody EFNs, while incomplete chemical characterization constrains the evaluation …

Effect Of Virtual Reality Intervention Of Postoperative Pain In Pediatric Surgical Patients, Tara L. Kempker

Dissertations

Problem: Pediatric surgical procedures are associated with preoperative anxiety. Preoperative anxiety is associated with higher postoperative pain. Multiple studies have found that decreasing preoperative anxiety using Virtual Reality (VR) Intervention also decreases postoperative pain scores and use of rescue analgesics in postoperative care units (PACU). However, there is no standardized protocol for use of VR interventions and in our institution, VR was not utilized at all.

Methods: This quality improvement (QI) initiative utilized a quasi-experimental design and convenience sampling. Quantitative data was collected during visits for scheduled operative visits for pediatric surgical patients ages seven to 18 years …

Multiple Event Segmentation Mechanisms In The Human Brain, Tan T Nguyen, Joset A Etzel, Matthew A Bezdek, Jeffrey M Zacks

2020-Current year OA Pubs

The human brain segments continuous experience into discrete events, with theoretical accounts proposing two distinct mechanisms: creating boundaries at points of high

Extrafloral Nectaries In Woody Plants: Toward An Integrated Framework For Ant-Mediated Plant Defense, Fangming Liu, Qifei Cai, Victor Busov, Zhen Liu

Michigan Tech Publications

Extrafloral nectaries (EFNs)-secretory structures that recruit predatory arthropods as indirect defenders against herbivory-have been studied almost exclusively in herbaceous systems, leaving a critical gap in our understanding of plant defense in woody plants. In trees, secondary growth, ontogenetic regulation, and seasonal phenology generate structural and temporal heterogeneity in EFN expression poorly captured by existing frameworks. We synthesize evidence across structural, chemical, and functional dimensions of EFN biology to develop an integrated framework for perennial trees. Our analysis suggests that methodological limitations in EFN detection likely bias the current chemical record of woody EFNs, while incomplete chemical characterization constrains the evaluation …

Full Issue: Summer 2026

DePaul Magazine

In DePaul Magazine's summer 2026 issue, learn how DePaul is living its Vincentian mission through innovative community engagement and service learning, exemplified by its Irwin W. Steans Center and Speech Language Pathology and Occupational Therapy graduate programs. Also, meet alumna Kate Steinberg who revisits her youth and DePaul days as a rising social media influencer, get the latest news from DePaul's 10 colleges and schools, and much more.

Tips For Growing Garden Vegetables In Utah: Soil Fertilization, Gastone Makalaya, Josh Martin, Milena Oliveira

All Current Publications

A successful vegetable garden requires precise nutrient management to achieve maximum yields. Fertilization must provide adequate nutrients to support plant growth throughout the season. Fertilizer applications should be based on soil test recommendations and crop nutrient requirements. This fact sheet provides Utah gardeners with practical guidance and tips on soil fertilization for vegetable gardening.

Constructing A Lower-Bound Estimate Of The Global Number Of Insect Species On A Hyperdiverse Empirical Foundation, Robert Colwell, Laura Melissa Guzman, Dirk Steinke, Anne Chao, Daniel H. Janzen, Winnie Hallwachs, Austin Baker, Jose L Fernández-Triana, Paul D.N. Hebert, Frank Joyce, Robert Puschendorf, Donald L.J. Quicke, Rodolphe Rougerie, M. Alex Smith, Nelson Zamora, Michael J. Sharkey

School of Biological and Marine Sciences

Estimating the number of insect species on Earth is a daunting challenge. The current consensus estimate—about six million species—is likely far too low, as we will show. Our estimate of the global number of insect species rests on a sample of more than 1,600,000 DNA-barcoded insect specimens representing 53,945 species from 15 “core” Malaise traps deployed in dry forest, cloud forest, and rainforest ecosystems of the Área de Conservación Guanacaste (ACG) in Costa Rica. Even this massive sample fails to reveal the full extent of ACG insect species richness. To estimate total ACG insect richness, we adjust the observed count …

Tau Pathology In Epilepsy: Emerging Mechanisms And Translational Opportunities, Arjune Sen, Xin You Tai, Aristea Galanopoulou, Maria Thom, Eleonora Aronica, Lucy Vivash, Martin Hardmeier, Action Amos, Stephan Rueegg, Matthias Koepp, Yaroslav Winter, Christoph Helmstaedter, Jeffrey L Noebels, Hilal A Lashuel, Terence J O'Brien

Faculty, Staff and Students Publications

The onset of epilepsy in adulthood occurs most commonly after 55 years of age. Given the ageing global population, this disorder represents an increasing burden on healthcare and society. The bidirectional link between epilepsy and dementia is a focus of intense research with underlying tau pathology highlighted as a potential mechanistic link. In this review, we examine the evidence for tau-related neurodegenerative processes in epilepsy beginning with how changes in biochemical and structural properties of the tau protein can lead to abnormal phosphorylation and pathological aggregation. We consider the role of tau in seizure occurrence and cognitive difficulties in experimental …

Dietary Fat Intake And Its Influence On The Association Between Liver Fat And Brain Choline Metabolism In Young Saudi Women, Halima S. Hawesa, Mansour E. Shanawani, Haya A. Alshegri, Mahasin G. Hassan, Amal I. Alorainy, Nouf A. Alroqaiba, Shanoo G. A. Sheikh

Saudi Medical Journal

Objective: Fat-rich nutrition may influence the neurochemical consequences of hepatic lipid accumulation. This study examined whether percent energy from fat modifies the association between liver fat and the brain (Cho/Cr) ratio in healthy young women. Methods: A total of 109 healthy Saudi women aged 18–25 years underwent brain magnetic resonance spectroscopy (¹H-MRS) to quantify Cho/Cr ratios. Liver fat was estimated using MRI-based proton density fat fraction (PDFF), and lipid intake was assessed using a validated food frequency questionnaire. Multivariable regression models tested the interaction between liver fat and fat-derived energy intake, followed by simple slopes analysis, regression …

Effects Of Maternal Vitamin D Supplementation During Pregnancy And Lactation On Immune Development In Offspring: A Systematic Review, Kurnia Maidarmi Handayani, Ghaniyyatul Khudri, Laura Zeffira, Widia Sari

Chulalongkorn Medical Journal

Background: Vitamin D, a fat-soluble prohormone, is essential for skeletal health and plays a key role in immune regulation. Deficiency is common among pregnant and lactating women, raising concerns as fetal and neonatal vitamin D status relies entirely on maternal stores. Insufficiency during these periods is linked to preterm birth, low birth weight, and immune-mediated disorders. This review examines the effects of maternal vitamin D supplementation on the immune development of offspring.

Methods: A systematic review was conducted in accordance with PRISMA guidelines and registered in PROSPERO (CRD420251117397). Experimental rodent studies published between 2019 and 2022 that investigated maternal vitamin …

Skip Segment Hirschsprung's Disease: Report Of A Rare Case And Literature Review, Nimmita Srisan, Paisarn Vejchapipat, Natcha Wanpiyarat

Chulalongkorn Medical Journal

We present an unusual case of skip segment Hirschsprung’s disease which was initially diagnosed with total colonic aganglionosis. A term male newborn presented with distal intestinal obstruction underwent exploratory laparotomy at three days old after ultrasound-guided contrast enema. Intra-operative frozen section of the full-thickness biopsies of each part of the colon and terminal ileum reported no ganglion cells, so we performed double-end ileostomy. Although all the final pathology reports confirmed no ganglion cells similar to the frozen sections, we were curious about the problematic bowel because of preoperative imaging (at the age of 30 months) which showed dilated transverse colon. …

Bridging The Gap Between Research And Practice In Schools, Giorgio Ostinelli

Journal of Educational Research and Practice

This case study examined how a group of Swiss primary school teachers collaborated with a school improvement advisor/researcher (SIA); it is now part of a larger project that uses a design-based methodology. The SIA is a rising entity in the educational landscape and serves as a state-mandated coach who bridges the gap between universities and schools. The SIA embodies the characteristics of both an educational researcher and a school advisor/coach. The SIA experience was created and designed using a frame–object, a valuable tool for collaboratively building professional development experiences with teachers and coaches. Understanding by Design served as the frame–object …