Digital Commons Network^™

College Student Utilizing Dating Apps During The Covid-19 Pandemic, Sarah Boll

Communication Undergraduate Honors Theses

The following study explores the effect of the global COVID-19 pandemic on the initiation and development of human relationships. During the early days of the pandemic, governments forced shutdowns of businesses and workplaces, and public health officials created social-distancing and facial covering mandates to protect the health of citizens. However, long periods of isolation can foster negative emotions and feelings, such as loneliness, anxiety, and depression. According to Maslow’s Hierarchy of Needs, humans have an innate need for love and belonging, but the health risks of contracting the virus and social-distancing enforcements significantly threatened the “normal” methods of satisfying this …

Development And Implementation Of A Protocol For Denosumab Administration In An Outpatient Infusion Clinic, Erin Stavrakas

The Eleanor Mann School of Nursing DNP Capstone Projects

Denosumab, or Prolia, is a medication given to increase bone mineral density (BMD) and prevent fracture risk in patients with osteoporosis. Guidelines for monitoring of side effects, data on long-term effects, and appropriate precautions are still being researched and developed. Healthcare teams are often unaware of preventative care measures to guide informed clinical decision making and patient care management. The recognized gap in care also reduces the standardization of health care delivery in clinics administering Prolia; this gap can lead to errors and miscommunication between patients and healthcare teams an increased risk for side effects. The aim of this translation …

Improving Depression Screening And Follow-Up Care In Underserved Populations, Alicia D. Hankins

The Eleanor Mann School of Nursing DNP Capstone Projects

Depression is a substantial source of financial, emotional, and physical burdens to patients and their families worldwide. It also disproportionately affects economically disadvantaged populations. To combat the depression crisis, The United States Preventive Services Task Force (USPSTF) published guidelines to boost depression screenings of all patients presenting for healthcare services. A review of literature and the completed needs assessment confirmed low rates of depression screening in the rural primary care sector. This project took place in an outpatient primary care facility in rural Arkansas, where current depression screening tools were not being used. The goal was to increase the percentage …

Insomnovation – Natural Sleep Solutions Business Plan, Nikolas Limperis

Finance Undergraduate Honors Theses

Currently, 70 million Americans suffer from some sort of sleep issues from trouble falling asleep, trouble staying asleep, and daytime drowsiness. However, the sleep solutions on the market today are either highly artificial or only address the symptoms of sleep issues rather than the underlying cause. This is what Insomnovation seeks to address. By providing supplementation to seven key vitamins and minerals, Insomnovation hopes to bring a natural solution to put the issue of sleep disorders to rest.

An Engineering And Economic Analysis Of The Implementation Of The Carbo Rock-It, Lydia Huck

Graduate Theses and Dissertations

The patented Carbo Rock-It system was developed to carbonate beverages for the craft brewing industry with the goal of reducing time, cost, and environmental impacts of the carbonation process. This research field tests, models, analyzes and optimizes the engineering and economic performance of a commercial-scale Carbo Rock-It placed in production at an operating brewery (Core Brewing and Distilling Co., Springdale, AR). Field tests indicated that the Carbo Rock-It was able to successfully carbonate twelve 120 BBL batches of Scarlet Letter Seltzer to 3.0 vol/vol while meeting all beverage quality and safety requirements. The Carbo Rock-It was able to reduce carbonation …

Studying Acetylation Of Aconitase Isozymes By Genetic Code Expansion, Jessica Araujo

Graduate Theses and Dissertations

The tricarboxylic acid (TCA) cycle is a very important, centrally located, energy-producing pathway that connects numerous other metabolic and regulatory pathways. Enzymes of this cycle have been more recently implicated in various cancers and neurometabolic disorders, however, the exact mechanism by which this happens becomes quite complex when considering the potential modification of these enzymes and the presence of multiple forms of the enzymes and therefore there is much to be studied in this area.

Aconitase has become a recent enzyme of interest as its substrate, citrate, has been found to play a major role in many vital processes within …

Economic Viability Of Weed Management Strategies In High-Tunnel Tomato, Gracie Morrison

Crop, Soil and Environmental Sciences Undergraduate Honors Theses

Cost-effective weed suppression is an important consideration for tomato growers. Growers often choose methods which minimize hand labor, as hand weeding can be prohibitively expensive. This project determined economic viability of high tunnel tomatoes treated with several methods of weed control, both organic and chemical. These methods included: 2-week hand weeding, 1-week hand weeding, preemergent, straw, landscape fabric, and untreated weedy control plots. These treatments were applied to randomized blocks in a high-tunnel. Weeding, planting, and harvest were all timed to determine labor and material costs of weed management strategy implementation. After harvest, marketable yield was weighed to determine revenue. …

Using Community Science To Assess The Effect Of Wing Pattern And Weather On Butterfly Behavior, Abbigail Merrill

Animal Science Undergraduate Honors Theses

Signaling in insects is used as communication and for attraction of mates. The physical appearance of the insect as well as conditions such as weather can play a role in visual signaling, by influencing the wavelengths of light available, and subsequent signal detection. We do not know, however, whether signals butterflies present broadly correlate with how they behave. In this study, we looked at the wing patterns and behavior of butterflies in Northwest Arkansas over a 3.5-year period to assess the relationship between wing pattern, weather, and behavior. We used observational data collected by hundreds of University of Arkansas students …

Effects Of Cottonseed Meal Containing Gossypol On Testis Physiology In Boars, Kristin Ryan

Animal Science Undergraduate Honors Theses

Feral hogs are an invasive species found in 35 U.S. states without an effective control method to limit their population growth. According to a 2019 survey of 467 landowners in Arkansas, feral hogs caused an estimated $12 million in damages (Cook, 2019). While there are current control methods such as hunting and trapping, 65% of the feral hog population must be eliminated in a specific area to prohibit population growth (Cook, 2019). It is theorized that gossypol, a phenolic compound known to negatively impact reproductive function in other species, could cause sterility in boars. In this preliminary research study, 21 …

Drug-Facilitated Sexual Assault At The University Of Arkansas, Barrett Weidman

Chemical Engineering Undergraduate Honors Theses

This work was written to fulfill two main purposes. First, to help survivors of Drug-Facilitated Sexual Assault (DFSA) process their experience by compiling the toxicological, pharmacological, and distribution of the three most used date-rape drugs. Second, to gauge the knowledge and interest of University of Arkansas students regarding drug impairments, sexual assault education, and bystander intervention training. A survey was conducted for the latter and revealed that 91.6% of students believe the University’s existing sexual assault prevention education and bystander intervention training have room for improvement. Also, 37.1% of students who have received this education report that the programming does …

Isolation And Production Of Tandem Collagen Binding Domain From Clostridial Collagenase Colg And Developments In C1q Reagent Production For Future Molecule Characterization Work, Stephanie Beitle

Chemical Engineering Undergraduate Honors Theses

This thesis covers a two part project: the production methods to create a double collagen binding domain molecule with a growth factor for wound healing applications and the development of a new in-house production method for isolating C1q from bovine blood. The wound healing molecule was created using transformation, sonication, and purification before being tested via electrophoresis SDS page and Western blots to confirm the molecule’s presence. The C1q in-house production method utilizes an ultrafiltration flow cell rather than dialysis at a critical point in the process, allowing for researchers to not only be able to use a single small …

Willow Creek Internship: The Effects Of Delayed Bathing On The Health Of Mothers And Newborns Post-Birth, Cara Yates

The Eleanor Mann School of Nursing Undergraduate Honors Theses

The implications of newborn bathing have become a rising topic in couplet care. The practice of bathing after birth can be linked to many things such as glucose control, temperature stability and exclusive breastfeeding. The timing of the initial bath also has effects on immediate skin to skin time between newborn and mother and therefore effects the initial bonding period post birth. This paper explores the current research on this practice.

Pediatric Seizure Management With Ketogenic Diet, Lydia Beller

The Eleanor Mann School of Nursing Undergraduate Honors Theses

Seizure disorders can be life altering and debilitating, especially for developing children. Children who have seizure disorders often require social, emotional, educational, and behavioral adjustments for children. Most medication regimes do not achieve complete management of seizure frequency and intensity. For children, seizure disorders can lead to unsuccessful education experiences, low self-esteem, severe injury, and difficulties with social skills and engagement. Discovering that a dietary means can reduce their frequency and intensity is groundbreaking. The ketogenic diet is a high protein, high fat, and almost no carbohydrate diet. The ketogenic diet is an effective non-pharmacological method for treating epilepsy (Karimzadeh, …

Essential Amino Acid (Eaa) Regulation Of Skeletal Muscle Protein Turnover With Age, Mary Komp

Graduate Theses and Dissertations

Skeletal muscle (SM) is vital for both long term health and quality of life. Recent research suggests an increase in catabolic signals with age triggers pathologic conditions, such as sarcopenia. Although results from in vitro studies model how EAA can regulate muscle protein synthesis (MPS), the relevance of these models to muscle protein breakdown (MPB) and the presence of physiological EAA concentrations remains to be established. Therefore, the objective of this study was to determine the effects of a low, normal, and supra physiological dose of EAA (0.2, 1.0, and 3.0 x EAA) in a young (passages 2-10) and aging …

Effects Of One-Pass Microwave Drying On Rice’S Utilization In The Brewing Process., Christopher Stuckey

Food Science Undergraduate Honors Theses

Rice is utilized as an adjunct grain by the beer manufacturing industry. Before utilization, the rice has to be dried to a desired moisture content. The drying process employed may have an impact on the rice’s physicochemical properties which influence the rice’s performance in the brewing process. This study focused on investigating the impact of microwave drying on rice’s physicochemical properties and utilization in the brewing process. Rough rice samples at an initial moisture content of 19.7% wet basis were exposed to microwave dryer set to deliver 525 kJ/kg of energy in a single drying pass. The effects of the …

Differential Neural Correlates Underlying Different Cognitive Control Strategies And Their Relationship With The Barratt Impulsiveness Scale, Carroll Bentley

Psychological Science Undergraduate Honors Theses

Impulsivity is defined as a rapid unplanned action to a stimulus, where the person does not consider the consequences of their actions (Moeller et al., 2001). Various measurement techniques exist in the study of impulsivity and include self-report, behavioral and physiological measures. This breadth of measurement techniques affords researchers the opportunity to understand what is likely a multifaceted nature of this construct. Previous literature shows mixed results between the relationship of the three measures. The present study seeks to add clarity between the three different modalities of measuring impulsivity. To address this relationship, an undergraduate sample (n = 171) completed …

Moral Distress, Burnout, And Moral Injury In Healthcare Professionals, Sophia Gibson

Anthropology Undergraduate Honors Theses

For doctors and other health care professionals, experiences of care too often involve burnout and moral distress. Making both visible to begin addressing them takes up the main concern of my thesis. Burnout and moral distress swallow a life. Suddenly you aren’t going on that shopping trip with friends, you can forget about going to that movie or play. You are too tired to drag yourself out of bed, instead getting caught in a cycle of sleep and work with no time for a break or even to process what happened last shift. Who’s going to have a nice relaxing …

Attention, Reflection, And Contemplation: Approaching The Divine Through Romantic Poiesis, Katelynn Tyner

English Undergraduate Honors Theses

Often the techniques of the said and the unsaid work together. This paper will explore ways in which poets embrace iconophilic or iconoclastic postures toward divine poiesis. One objective will be to focus on the arrangement of an abundance of images into itineraries and poetic landscapes. Another objective will be to demonstrate how these patterns of cultivation can be related to a divine poiesis. Through poetry, there are ways of attending to, reflecting on, and contemplating divine images that can return us to forms of participation with the sacred. First examining poetic attention, I identify poets who demonstrate …

Memory Hunger: A Geocritical Study Of Nostalgia And The Glorification Of Paris In Works Written By Lost Generation Writers During The Interwar Period., Gabrielle Vatthanatham

English Undergraduate Honors Theses

The literary representations of Paris in the works of the Lost Generation communicate a nostalgia, longing for, and glorification of an irrecoverable past. The romanticization and abstraction of the setting of Paris in the works of the Lost Generation elucidates the emotional situations of their characters as they contemplate the nature of their existence. The abstraction of Paris liberates the city from its physical locale and demonstrates the repressional mechanisms of anchoring and sublimation outlined by existential philosopher Peter Wessel Zapffe in his essay “The Last Messiah.” In the connection of Paris with Zapffe’s existential theory, Paris becomes, for certain …

The Hot Springs Creekway & The Rediscovery Of The Water That Made Hot Springs Famous, Zane Colvin

Landscape Architecture Undergraduate Honors Theses

Arkansas’s Hot Springs National Park was the first natural reservation in the United States and is the oldest park in the National Park System. In Hot Springs, 47 springs release almost a million gallons of potable 143° water every day - the problem is, almost all of this water is hidden from sight, funneled directly into an 1884-constructed tunnel underground, where no person (or other life) can experience it.

Hot Springs Creek should be daylighted and connected with the surrounding National Park, creating thermal 'pools' for public use, and restoring its banks to pre-settlement ecologically rich conditions. My plan to …

“Translation Of Hdac6 Pet Imaging Using [18f]Ekz-001 – Cgmp Production And Measurement Of Hdac6 Target Occupancy In Nhps” – A Review, Dania Rahal

Chemistry & Biochemistry Undergraduate Honors Theses

The inhibition of histone deacetylase 6 (HDAC6) has been reported to alleviate the effects of neurodegenerative diseases such as Alzheimer’s disease. The brain-penetrant PET radioligand [¹⁸F]EKZ-001 has high affinity and selectivity towards HDAC6 and therefore suggests great promise in therapeutic treatment studies and development for neurodegenerative diseases. “Translation of HDAC6 PET imaging using [¹⁸F]EKZ-001 – cGMP production and measurement of HDAC6 target occupancy in NHPs” has achieved an effective, fully automated method of producing [¹⁸F]EKZ-001 in compliance with current good manufacturing practices (cGMP) to support the translation of [¹⁸F]EKZ-001 PET for …

3d Volumetric Mapping Of Tissue Properties Via A Catheter-Scale Microendoscope Imaging System, Andrew Stark

Biomedical Engineering Undergraduate Honors Theses

The study of tumor microvasculature is an important area of interest for research and clinical communities; however, there are significant limitations in the clinical characterization of the tumor microenvironment. Optical methods offer quantitative real-time measurement of tissue structure and perfusion and can be miniaturized for deployment endoscopically into previously inaccessible locations. However, conventional optical methods (i.e., optical coherence tomography, white light endoscopy, etc.) gives limited information about tissue perfusion while the diameter of various optical probes along with the complexity of scanning mechanisms make it difficult to access certain areas. In this study, a new technique for characterizing the tumor …

Investigating The Impact Of Hypoxia On Reactive Oxygen Species Generation Within Murine Breast Cancer Cells, Jared Mcpeake

Biomedical Engineering Undergraduate Honors Theses

When cancer metastasizes from a primary tumor site to secondary site through the bloodstream or lymph, the cancer becomes more difficult to treat. For this reason, it is vital to study what indicates the metastatic potential of a tumor. Current research has shown that cell lines with high metastatic potential display increased levels of metabolic adaptability over their nonmetastatic counterparts after undergoing hypoxic conditions. One method of assessing this adaptability is to measure the concentration of reactive oxygen species (ROS) produced by the cells while undergoing oxidative stress. In highly adaptable metastatic cells, an increase of ROS buildup within the …

Erythrocyte Deformability In Response To Glucose Using Liquid Crystals, Jayden Goff

Biomedical Engineering Undergraduate Honors Theses

The worldwide prevalence of diabetes mellitus is rapidly increasing with about 9.3% of the adult population living with the disease. People with diabetes have trouble regulating their blood glucose levels which typically leads to hyperglycemia. Under normal physiological conditions, erythrocytes can undergo deformations in response to shear stress when passing through capillaries with a smaller diameter. Poorly managed hyperglycemia can lead to the glycosylation of erythrocyte membrane proteins and hemoglobin. This glycosylation leads to increased rigidity of the cells along with decreased deformability in response to mechanical stress; therefore, these cells have a higher susceptibility of getting stuck in the …

Atomic Force Microscopy Based Dna Sensing And Manipulation, Matthew Shubert

Mechanical Engineering Undergraduate Honors Theses

Sequencing DNA provides a positive impact for the biomedical community by understanding a wide variety of applications such as human genetics, disease, and pathogens. The reason the Arkansas Micro & Nano Systems lab is involved with research in DNA sequencing is due to the current, leading industry method. Nanopore sequencing was developed by Oxford Nanopore Technology in which its sequencing method separates double stranded DNA to electrically characterize individual nucleotides traveling through a charged nanopore. Unfortunately, nanopore sequencing uses biological materials that require a shelf life and drives high cost. Therefore, the Arkansas Micro & Nano Systems lab has developed …

Investigation Of The Binding Domain Interfaces Of The C-Terminus Of The Albino3 Insertase And The 43kda Chloroplast Signal Recognition Particle Subunit Via Single Molecule Förster Resonance Energy Transfer, Amanda Tomanek

Chemistry & Biochemistry Undergraduate Honors Theses

Fluorescent labeling is a technique used for visualizing functional groups contained in biomolecules by fluorescence imaging. This technique was used in this project to analyze post-translational targeting of light-harvesting chlorophyll-binding proteins (LHCP), which are the core complexes that harvest sunlight to drive photosynthetic electron transfer. This protein is synthesized in the cytosol and post-translationally targeted to the stroma of chloroplasts. CpSRP43 is a signal recognition particle (SRP) subunit unique to chloroplasts, which has been shown to interact with the stroma-soluble C-terminus of the thylakoid-bound Albino3 insertase (Alb3-Cterm). In the chloroplast stroma, targeting to thylakoids is performed via the cpSRP pathway …

The Effects Of Deletion Of The Cytoplasmic Domain Of Robo3 On Drosophila, Jessie Agcaoili

Biological Sciences Undergraduate Honors Theses

My research project examines how the deletion of the cytoplasmic domain affects the function of Robo3. If Robo3 is signaling repulsion in response to SLIT this activity should require the cytoplasmic domain. I investigated the functional importance of Robo3 by deleting the cytoplasmic domain of Robo3 using a CRISPR-based technique. This modified gene was then injected into Drosophila embryos where it replaced the normal copy of the gene. Embryos expressing the modified version of robo3 in place of normal robo3 were dissected and examined.

A Historical And Practical Analysis For Neuromarketing In Business Practices Today, Scott Wicinski

Marketing Undergraduate Honors Theses

What thoughts come to your mind when you think of the term neuromarketing? In a digital age where personal privacy seems to be diminishing and data exploitation appears to be rising, many people are skeptical about businesses' attempts to combine neurology, psychology, and business. This skepticism is unfortunately, legitimate. Our history reveals plenty of occasions where businesses have exploited their customers through unethical means and traded valuable relationships and resources for profits. However, despite the flaws business can introduce, business is arguably still the most powerful tool for creating value in a community. Through business, customers have had access to …

The Ethical Dilemmas Of The True Crime Genre, Jordan Smail

Marketing Undergraduate Honors Theses

Along with the recent mainstream popularity of true crime entertainment, the genre has been increasingly criticized for ethical violations. Interestingly, the centuries-long history of true crime and the moral debates around it has led to an abundance of literature on the subject with little to no consensus. The mere existence of true crime entertainment can even be considered controversial in some cases. For those who produce and market true crime content, a lack of common guidelines means receiving a wide range of feedback. This dichotomy of both backlash and praise being published about the same works reveals a gap in …

Quantification Of Dental Fissures Through Occlusal Topography Analysis, Duru Erkan

Biological Sciences Undergraduate Honors Theses

Narrow, deep, and elaborate dental fissures are widely believed to increase the predisposition of enamel to develop carious lesions as these surfaces are thought to be ideal for cariogenic bacteria to adhere to. Therefore, dentists prescribe sealants as a preventative measure for patients with such fissures to avoid tooth decay. Yet to date, there is no objective data supporting the notion that fissure morphology actually affects caries susceptibility, nor is there a quantifiable, clinically practical method to characterize fissure patterns expected to increase risk of caries disease.

In this study, three new methods to quantitatively characterize fissure pattern in mandibular …