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Characterization Of Human Fibroblast Growth Factor 2 Variant To Determine Effects On Structure, Stability, And Cell Proliferation, Ryan Layes

Graduate Theses and Dissertations

Fibroblast growth factors (FGFs) are a family of cell signaling proteins conserved across multiple species. Each individual FGF elicits different cellular functions including, but not limited to, proliferation, migration, differentiation, angiogenesis, and wound healing. One of the most studied members, fibroblast growth factor 2 (FGF2), has demonstrated substantial wound healing capacity in a wide range of tissues including skeletal, muscular, neural, respiratory, epithelial, and cardiovascular. This ability makes FGF2 a potential therapeutic for a wide range of conditions and injuries. However, due to a short half-life at room temperature, therapeutic use of FGF2 is limited. It has been demonstrated that …

Evaluating Differences In Optical Properties Of Indolent And Aggressive Murine Breast Tumors Using Quantitative Diffuse Reflectance Spectroscopy, Joel Rodriguez Troncoso, Umme Marium Mim, Jesse D. Ivers, Santosh K. Paidi, Mason G. Harper, Khue G. Nguyen, Sruthi Ravindranathan, Lisa Rebello, David E. Lee, David A. Zaharoff, Ishan Barman, Narasimhan Rajaram

Biomedical Engineering Faculty Publications and Presentations

We used diffuse reflectance spectroscopy to quantify tissue absorption and scattering-based parameters in similarly sized tumors derived from a panel of four isogenic murine breast cancer cell lines (4T1, 4T07, 168FARN, 67NR) that are each capable of accomplishing different steps of the invasion-metastasis cascade. We found lower tissue scattering, increased hemoglobin concentration, and lower vascular oxygenation in indolent 67NR tumors incapable of metastasis compared with aggressive 4T1 tumors capable of metastasis. Supervised learning statistical approaches were able to accurately differentiate between tumor groups and classify tumors according to their ability to accomplish each step of the invasion-metastasis cascade. We investigated …

Patterns In Winter Stonefly Distribution Along A River Continuum And Land-Use Gradient In Northwest Arkansas Streams, Zachary Tipton

Graduate Theses and Dissertations

Freshwater ecosystems are facing a crisis with extinction rates of aquatic species exceeding those of their terrestrial counterparts by up to fivefold. This decline is predominantly attributed to evolving land use patterns within watersheds, leading to chemical and physical transformations in freshwater habitats. Northwest Arkansas (NWA) represents one of the fastest-growing regions in the United States, undergoing substantial shifts in land use. Consequently, the status of aquatic life in this region remains uncertain. Addressing this concern, the latest Arkansas Wildlife Action Plan emphasizes the necessity of distribution and population data to guide conservation efforts for Species of Greatest Conservation Need …

A Cross-Sectional Study On The Impact Of The Covid-19 Pandemic On Sport-Related Concussion Clinical Presentation Within Adolescents And Adults, Emily Mcindoe

Graduate Theses and Dissertations

Introduction. The COVID-19 pandemic spanned across the globe in March 2020 and has since significantly impacted human life. There is evidence that supports symptom exacerbation and an increase in anxiety and depression in clinical presentation post-COVID-19 pandemic compared to pre-COVID-19 for multiple medical diagnoses. These medical diagnoses include migraines, post-traumatic stress disorder (PTSD), obsessive-compulsive disorder (OCD), and mild cognitive impairment. The effect that the pandemic had on the clinical presentation of sports-related concussions is understudied. It is possible that the COVID-19 pandemic has altered the clinical presentation of concussions as seen in other medical diagnoses. Given the increased reporting of …

Habitat Associations Of Plains Spotted Skunk (Spilogale Interrupta) Across The Plains Ecoregion. And The Landcover Occupancy Models Of The Gray Fox (Urocyon Cinereoargenteus) In The Southeastern Plains Region In Arkansas, Michael Shaw

Graduate Theses and Dissertations

Much of the landscape of the United States has been altered by humans, leading to the eradication of most populations of large mammalian predators. Consequently, many species of mammalian mesopredators (medium-sized mammalian predators) have come to dominate the landscape. Species such as the gray fox (Urocyon cinereoargenteus) may appear to be on the rise and doing well due to their widespread range, but at a local scale may need monitoring and less is known in areas of its range. Others such as the plains spotted skunk have a wide range across the plains but are on the decline even with …

Assessment Of Dietary Energy And Amino Acid Diet Formulation In The Modern Broilers, Matheus Freitas Costa

Graduate Theses and Dissertations

As a result of the advancement of genetics, understanding broiler requirements for dietary energy and amino acids is essential for improving live performance and carcass characteristics. The energy system used to formulate diets in poultry is based on metabolizable energy (ME); this equation can be described as the total amount of energy in the feed minus gases and feces. However, the net energy (NE) system may be the best depiction of the energy utilized by birds for production and maintenance purposes once the heat increment (HI) is measured. Thus, a series of studies were conducted to establish the responsiveness of …

Geospatial Analysis Of Weathering And Recession On Architectural Limestone At The 1891 Powerhouse/Icehouse In Eureka Springs, Arkansas, Stuart Bruce Wright

Graduate Theses and Dissertations

The objective of this study of the architectural limestone of the 1891 Powerhouse/Icehouse in Eureka Springs, Arkansas was to analyze the environmental factors that influenced the deterioration and surface recession of this historical stone structure. The focus of this research was to examine and establish a baseline study that may assist in future monitoring and documentation of this historic limestone structure on stone weathering. A replicable methodology was specifically created toward this baseline research in hopes that it represented a solid baseline study. Observations and data analyses revealed the relationship between the architectural limestone building structure and the dominating recession …

Tree-Ring Reconstruction Of Ouachita River Streamflow, Keaton Cade Jenkins-Joyce

Graduate Theses and Dissertations

The Ouachita River drains the Ouachita Mountains and Upper Coastal Plain in Arkansas and Louisiana. The Ouachita River is used for navigation, power generation, recreation, water supply, and wastewater treatment. The river has been prone to low flows during drought and extreme flooding, which were principal justifications for the construction of three large multipurpose dams on the stream. It is likely that the use of the Ouachita River will be stressed by future population growth, economic expansion, and climate change. For this study, tree-ring chronologies from various locations in and near the Ouachita River drainage basin were used to reconstruct …

Tissue-Engineered Models For Investigating Nerve Infiltration In Fibrotic Microenvironments, Nikolas Ala-Kokko

Graduate Theses and Dissertations

Neuron infiltration is involved in a multitude of diseased states and is critical in the regeneration of physiologic conditions. Modeling of innervation in three-dimensional, heterogenous, environments would allow early investigation in the crosstalk of neurons and native cells in normal and pathophysiologic microenvironments to gain an understanding of mechanistic functions. This would allow for greater insight into the role of metabolism, cell adhesion, microenvironmental alternations, cellular crosstalk, and signaling pathways that play a role in the promotion and prevention of neurite growth. In this thesis, with the construction of collagen-based hydrogels as the foundation for cell culture, we investigate cell …

Determination Of P Availability In Feedstuffs And The Effect Of Feedstuffs And Anti-Nutritional Factors On Secretory Iga Production And Host Nutrient Losses In Poultry, Benjamin Parsons

Graduate Theses and Dissertations

The availability of P in feedstuffs and the effect of feedstuffs, feed additives, and anti-nutritional factors on secretory IgA (sIgA) production in chickens were evaluated. A rapid method was developed using the precision-fed rooster assay to evaluate phytic acid disappearance, P digestibility, and phytase efficacy. Further, exogenous phytase was found to be effective at degrading myo-inositol 1,2,3,4,5,6-hexakis, however, the enzyme was less efficient at P release from lower inositol phosphates. The availability of P in feedstuffs was found to be affected by dietary Ca content, where increasing Ca linearly reduced (P < 0.05) both phytic acid hydrolysis and P digestibility. For example, the standardized ileal digestibility of P was reduced from 73 to 47% in soybean meal when the dietary Ca content was increased from 0.30 to 0.75%. The digestibility of P in distillers dried grains with solubles (DDGS) and corn fermented protein (CFP), however, was high across all Ca levels (71 to 80%). Relative P bioavailability based on tibia bone ash was also found to be high for DDGS and CFP, being 81 and 78%, respectively. Upon further evaluation, it was observed that utilizing low dietary Ca levels (0.30%) when P digestibility in individual plant-based feedstuffs was determined overestimated the P digestibility in practical grower diets by up to 16 percentage units. Utilization of higher Ca levels (0.75%) when P digestibility in individual plant-based feedstuffs was determined, however, resulted in calcualted P digestibility values that were within 1 to 3 percentage units of the measured digestibility in practical grower diets. Aside from P, feedstuffs were also evaluated to determine their effect on sIgA production in the intestine. Roosters excreted approximately 6 to 30 mg of sIgA / 24 h. Further, the proportional contribution of sIgA to total endogenous amino acid (AA) losses ranged from 1 to 13%, with the greatest contribution being observed for Trp. The addition of casein to a protein-free diet increased (P < 0.05) sIgA production in both roosters and broiler chickens. There was no change (P > 0.05) in sIgA production compared with the protein-free diet …

Sensory Input To Cortex Encoded On Low-Dimensional Periphery-Correlated Subspaces, Andrea K. Barreiro, Antonio J. Fontenele, Cheng Ly, Prashant Chama Raju, Shree Hari Gautam, Woodrow L. Shew

Physics Faculty Publications and Presentations

As information about the world is conveyed from the sensory periphery to central neural circuits, it mixes with complex ongoing cortical activity. How do neural populations keep track of sensory signals, separating them from noisy ongoing activity? Here, we show that sensory signals are encoded more reliably in certain low-dimensional subspaces. These coding subspaces are defined by correlations between neural activity in the primary sensory cortex and upstream sensory brain regions; the most correlated dimensions were best for decoding. We analytically show that these correlation-based coding subspaces improve, reaching optimal limits (without an ideal observer), as noise correlations between cortex …

The Spatial Dissimilarities And Connections Of The Microbiota In The Upper And Lower Respiratory Tract Of Beef Cattle, Zhihao Zhang, Chengqian Zhang, Yikai Zhong, Shuli Yang, Feilong Deng, Ying Li, Jianmin Chai

Animal Science Faculty Publications and Presentations

Bovine respiratory disease (BRD) causes morbidity and mortality in cattle. The critical roles of the respiratory microbiota in BRD have been widely studied. The nasopharynx was the most popular sampling niche for BRD pathogen studies. The oral cavity and other niches within the respiratory tract, such as nostrils and lung, are less assessed. In this study, oropharyngeal swabs (OS), nasal swabs (NS), nasopharyngeal swabs (NP), and bronchoalveolar lavage (BAL) were collected from calves located in four countries and analyzed for investigation of the dissimilarities and connections of the respiratory microbiota. The results showed that the microbial diversity, structure, and composition …

Editorial: Respiratory Microbiome In Health And Disease, Yimin Zhuang, Tao Ding, Jiangchao Zhao, Jianmin Chai

Animal Science Faculty Publications and Presentations

Editorial on the Research Topic:

Respiratory microbiome in health and disease

Coordinated Regulation Of Myonuclear Dna Methylation, Mrna, And Mirna Levels Associates With The Metabolic Response To Rapid Synergist Ablation-Induced Skeletal Muscle Hypertrophy In Female Mice, Ahmed Ismaeel, Nicholas T. Thomas, Mariah Mccashland, Sebastian Edman, Johanna T. Lanner, Vandré C. Figueiredo, Christopher S. Fry, John J. Mccarthy, Yuan Wen, Kevin A. Murach, Ferdinand Von Walden

Health, Human Performance and Recreation Faculty Publications and Presentations

The central dogma of molecular biology dictates the general flow of molecular information from DNA that leads to a functional cellular outcome. In skeletal muscle fibers, the extent to which global myonuclear transcriptional alterations, accounting for epigenetic and post-transcriptional influences, contribute to an adaptive stress response is not clearly defined. In this investigation, we leveraged an integrated analysis of the myonucleus-specific DNA methylome and transcriptome, as well as myonuclear small RNA profiling to molecularly define the early phase of skeletal muscle fiber hypertrophy. The analysis of myonucleus-specific mature microRNA and other small RNA species provides new directions for exploring muscle …

Characterizing The Impact Of Enterococcus Cecorum Infection During Late Embryogenesis On Disease Progression, Cecal Microbiome Composition, And Early Performance In Broiler Chickens, Marcela Arango, Aaron Forga, Jing Liu, Latasha Gray, Randy Moore, Makenly E. Coles, Abdiel Atencio, Carolina Trujillo, Juan David Latorre, Guillermo Tellez-Isaias, Billy Hargis, Danielle Graham

Poultry Science Faculty Publications and Presentations

Enterococcus cecorum (EC) has been associated with septicemia and early mortality in broiler chickens. There is limited research investigating the pathogenicity of EC field strains obtained from affected birds. The purpose of this study was to evaluate the effect of in-ovo administration into the amnion with different EC field isolates at d 18 of embryogenesis (DOE18). In Exp 1, 7 EC field isolates alone or in combination (EC1–EC3, EC4–EC5, EC6, and EC7) were selected based on phenotypic characteristics and evaluated at different concentrations (1 × 10², 1 × 10⁴, and 1 × …

An Amplification-Free Crispr-Sers Biosensor For Specific, Sensitive And Rapid Detection Of Salmonella Typhimurium In Poultry, Fei Jia, Bingyan Li, Yawen He, Yafang Shen, Juhong Chen, Xingmin Li, Yanbin Li

Biological and Agricultural Engineering Faculty Publications and Presentations

CRISPR (Clustered regularly interspaced short palindromic repeats) has been a cutting-edge biotechnology in both gene editing and biosensing due to its desirable features, such as high base resolution and set-and-forget operation. However, as a nucleic acid detection method, an DNA/RNA amplification procedure is still inevitable in CRISPR biosensors. In this study, a highly-ordered nanopore array SERS substrate, coated with silver nanoparticles, was fabricated and utilized as a platform for the specific detection of Salmonella Typhimurium (S. Typhimurium) without the time-consuming DNA amplification step. The smart sensing strategy was established by introducing an ssDNA labeled with a Raman active molecule …

Web 2 Vs. Web 3 Paths To The Metaverse: Who Is Leading? Who Should Lead?, Le Kuai, Mary Lacity, Jeffrey K. Mullins

Information Systems Faculty Publications and Presentations

Our research investigates two questions: Who is leading the metaverse? Who should lead? The questions are important because metaverse will have significant consequences for individuals, businesses, and society. We examined the current leaders of metaverse on two evolutionary paths, namely Web 2 and Web 3. Based on regulatory reports, corporate press releases, and patents, we found that only a handful of Web 2 companies are “all-in” on metaverse, and at least one of these enterprises, Meta, is on track to end up as a dominant platform provider. Based on market capitalization, user activity, and patents, only a handful of Web …

Aqueous Ozone Efficacy For Inactivation Of Foodborne Pathogens On Vegetables Used In Raw Meat-Based Diets For Companion Animals, Sahaana Chandran, Christopher A. Baker, Allyson N. Hamilton, Gayatri R. Dhulappanavar, Sarah L. Jones, Kristen E. Gibson

Food Science Faculty Publications and Presentations

The present study evaluates the efficacy of a batch wash ozone sanitation system (BWOSS) and spray wash ozone sanitation system (SWOSS) against Listeria monocytogenes (two strains) and Salmonella enterica subsp. enterica (three serovars) inoculated on the surface of carrots, sweet potatoes, and butternut squash, commonly used in raw meat-based diets (RMBDs) marketed for companion animals such as dogs and cats. Produce either remained at room temperature for 2 h or were frozen at −20°C and then tempered overnight at 4°C to mimic the preprocessing steps of a raw pet food processing operation (‘freeze-temper’) prior to ozone treatment. Two ozone concentrations …

Innovative Approaches To Poultry Processing Wastewater Treatment: The Stainless Steel Ultrafiltration Membrane As A Viable Option, Saubana Olorunrola Dada, Chidambaram Thamariselvan, Mahmood Jebur, Sumith Ranil Wickramasinghe

Chemical Engineering Faculty Publications and Presentations

In pursuit of sustainability, we explored replacing conventional dissolved air floatation (DAF) in poultry processing wastewater (PPW) treatment with a precisely tuned 0.02 µm stainless-steel ultrafiltration (SSUF) membrane. SSUF is a robust, homogenously porous membrane with strong chemical resistance, ease of cleaning, and exceptional resistance to organic fouling. Unlike polymeric membranes, it can be regenerated multiple times, making it a cost-effective choice due to its compatibility with harsh chemical cleaning. The PPW used for the study was untreated wastewater from all processing units and post-initial screening. Our study revealed the SSUF membrane’s exceptional efficiency at eliminating contaminants. It achieved an …

The Alternative Livestock Revolution: Prospects For Consumer Acceptance Of Plant-Based And Cultured Meat In South Africa, Chiedza Tsvakirai, Lawton Nalley, Shelby Rider, Ellen Van Loo, Makgopa Tshehla

Agricultural Economics and Agribusiness Faculty Publications and Presentations

Although South Africa accounts for half of the alternative meat market for the African continent, there remains a lack of information about consumer demand for plant-based and lab-cultured meat and its market potential domestically. This study reports the results of a nationwide survey of 649 South African consumers who completed a choice experiment in which they selected among conventional beef and three alternative burger patties at varying prices. Results indicate that holding prices constant and conditional on choosing a food product, 21% of the market share was estimated for plant-based meat alternatives and 38% for lab-cultured meat.

Leucine Supplementation Exacerbates Morbidity In Male But Not Female Mice With Colorectal Cancer-Induced Cachexia, Eleanor R. Schrems, Wesley S. Haynie, Richard A. Perry Jr., Francielly Morena, Ana Regina Cabrera, Megan E. Rosa-Caldwell, Nicholas P. Greene, Tyrone A. Washington

Health, Human Performance and Recreation Faculty Publications and Presentations

Cancer cachexia (CC) is a multifactorial wasting syndrome characterized by a significant loss in lean and/or fat mass and represents a leading cause of mortality in cancer patients. Nutraceutical treatments have been proposed as a potential treatment strategy to mitigate cachexia-induced muscle wasting. However, contradictory findings warrant further investigation. The purpose of this study was to determine the effects of leucine supplementation on skeletal muscle in male and female Apc^Min/+ mice (APC). APC mice and their wild-type (WT) littermates were given normal drinking water or 1.5% leucine-supplemented water (n = 4–10/group/sex). We measured the gene expression of regulators of …

Understanding Functional Benefits Of Isoleucine And Arginine On Poultry Performance And Health., Roshan Adhikari, Jason T. Lee, Keith Haydon

Proceedings of the Arkansas Nutrition Conference

Poultry industry is rapidly moving towards utilizing the best ingredients to precisely feed the birds for better performance, welfare, health, and profitability. One of the practices that evolved over time with research is better optimization of amino acid utilization in the diets thus changing the crude protein landscape. Historically, if we compare the modern diets to diets from 1980, significant changes are visible in the use of unbound or crystalline amino acids leading to reduced levels of CP and reduced unutilized nitrogen in the diets. Multiple feed-grade amino acids are available in a cost-effective manner in poultry diets. Multiple research …

The Himalayan Uplift And Evolution Of Aquatic Biodiversity Across Asia: Snowtrout (Cyprininae: Schizothorax) As A Test Case, Binod Regmi, Marlis R. Douglas, Karma Wangchuk, Zachery D. Zbinden, David R. Edds, Singye Tshering, Michael E. Douglas

Biological Sciences Faculty Publications and Presentations

Global biodiversity hotspots are often remote, tectonically active areas undergoing climatic fluctuations, such as the Himalaya Mountains and neighboring Qinghai-Tibetan Plateau (QTP). They provide biogeographic templates upon which endemic biodiversity can be mapped to infer diversification scenarios. Yet, this process can be somewhat opaque for the Himalaya, given substantial data gaps separating eastern and western regions. To help clarify, we evaluated phylogeographic and phylogenetic hypotheses for a widespread fish (Snowtrout: Cyprininae; Schizothorax) by sequencing 1,140 base pair of mtDNA cytochrome-b (cytb) from Central Himalaya samples (Nepal: N = 53; Bhutan: N = 19), augmented with 68 GenBank …

Potent Bile Acid Microbial Metabolites Modulate Clostridium Perfringens Virulence, Tahrir Jatli Alenezi, Ying Fu, Bilal Alrubaye, Thamer Alanazi, Ayidh Almansour, Hong Wang, Xiaolun Sun

Poultry Science Faculty Publications and Presentations

Clostridium perfringens is a versatile pathogen, inducing diseases in the skin, intestine (such as chicken necrotic enteritis (NE)), and other organs. The classical sign of NE is the foul smell gas in the ballooned small intestine. We hypothesized that deoxycholic acid (DCA) reduced NE by inhibiting C. perfringens virulence signaling pathways. To evaluate the hypothesis, C. perfringens strains CP1 and wild-type (WT) HN13 and its mutants were cultured with different bile acids, including DCA and isoallolithocholic acid (isoalloLCA). Growth, hydrogen sulfide (H₂S) production, and virulence gene expression were measured. Notably, isoalloLCA was more potent in reducing growth, H …

Editorial: Parasitism: The Good, The Bad And The Ugly, Marco A. Juarez-Estrada, Danielle Graham, Xochitl Hernandez-Velasco, Guillermo Tellez-Isaias

Poultry Science Faculty Publications and Presentations

Editorial on the Research Topic

Parasitism: the good, the bad and the ugly

Snapshot Of The Research Publications From The Department Of Biological Sciences, University Of Arkansas, 2019-2022, Lutishoor Salisbury, Jeremy Smith

University Libraries Faculty Publications and Presentations

This report provides a snapshot of the research publications for the Department of Biological Sciences for a four-year period.

It includes tables identifying the types of publications, the research collaboration between faculty and students (graduates and undergraduates); the JCR ranking of the journals in which they published and a listing of their publications, etc.

Design, Fabrication, And Evaluation Of 3-D-Printed Cystotomy Spoons As A Retrieval Method In Dogs, Davina C. D'Angelo, Sam E. Stephens, Morten O. Jensen, Lauren R. Thomas

Animal Science Faculty Publications and Presentations

OBJECTIVE

Current cystotomy methods often implement the use of off-label devices, resulting in urocystolith extraction difficulty and potentially leading to postoperative complications and discomfort for the patient. The objective of this study was to create 3 novel 3-D printed cystotomy spoons that offer a dedicated solution for removing urocystoliths from a patient's urinary bladder.

ANIMALS

Clinical use of the 3 novel 3-D printed cystotomy spoons were ultimately evaluated in 4 dogs and 1 cat that presented for urocystotlith removal at 3 different veterinary hospitals in northwest Arkansas.

METHODS

The novel cystotomy spoons were designed using SolidWorks, 3-D printed with a …

Temperate Silvopastures Provide Greater Ecosystem Services Than Conventional Pasture Systems, Helen C.S. Amorim, Amanda Ashworth, Peter L. O'Brien, Andrew L. Thomas, Benjamin R. Runkle, Dirk Philipp

Crop, Soil and Environmental Sciences Faculty Publications and Presentations

Management and design affect systems’ ability to deliver ecosystem services and meet sustainable intensification needs for a growing population. Soil–plant–animal health evaluations at the systems level for conventional and silvopastoral environments are lacking and challenge adoption across temperate regions. Impacts of silvopasture on soil quality, microclimate, cattle heat stress, forage quality and yield, and cattle weight gain were compared to a conventional pasture in the mid-southern US. Here, we illustrate silvopastures have greater soil organic carbon, water content, and overall quality, with lower temperatures (soil and cattle) than conventional pastures. Forage production and cattle weight gains were similar across systems; …

The Effects Of Landscape And Yard Features On Mammal Diversity In Residential Yards Within Northwest Arkansas, Usa, Emily P. Johansson, Brett A. Degregorio

Biological Sciences Faculty Publications and Presentations

The human footprint is rapidly expanding, and wildlife habitat is continuously being converted to human residential properties. Surviving wildlife that reside in developing areas are displaced to nearby undeveloped areas. However, some animals can co-exist with humans and acquire the necessary resources (food, water, shelter) within the human environment. This ability to coexist may be particularly true when development is low intensity, as in residential suburban yards. Yards are individually managed “greenspaces” that can provide a range of food (e.g., bird feeders, compost, gardens), water (bird baths and garden ponds), and shelter (e.g., brush-piles, outbuildings) resources and are surrounded by …

Isolation, Characterization, And Experimental Infection Of Streptococcus Gallolyticus Subspecies Pasteurianus From Commercial Turkeys With Acute Septicemia: A Pilot Study, L. S. Gray, J. D. Latorre, D. Hernandez-Patlan, B. Solis-Cruz, V. Petrone-Garcia, X. Hernandez-Velasco, K. M. Robbins, R. W. Moore, C. N. Vuong, A. Stein, L. Laverty, K. Martin, M. E. Coles, R. Señas-Cuesta, J. M. Diaz-Gomez, I. Loeza, I. Castellanos-Huerta, J. A. Maguey-Gonzalez, B. D. Graham, B. M. Hargis, G. Tellez-Isaias

Poultry Science Faculty Publications and Presentations

Streptococcus gallolyticus (SG) is a Gram-positive cocci found as commensal gut flora in animals and humans. SG has emerged as a cause of disease in young poults between 1 and 3 wk of age. SG is associated with septicemia resulting in acute mortality with no premonitory signs in turkeys. Three SG isolates were obtained from clinical field cases of acute septicemia of commercial turkeys and used in three independent experiments. In Experiment 1, embryos were inoculated 25 d of embryogenesis with varying concentrations of SG1, SG2, or SG3. In Experiment 2, day of hatch, poults were inoculated with varying concentrations …