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Precision Imaging For Head And Neck Tumors, Logan Daniel Stone Jan 2025

Precision Imaging For Head And Neck Tumors, Logan Daniel Stone

All ETDs from UAB

Antibody-based imaging modalities have become more common in the field of imaging oncology as more biomarkers are identified for certain cancers. Epidermal growth factor receptor (EGFR) is overexpressed in several cancer types including head and neck squamous cell carcinoma (HNSCC) and ameloblastoma (AB). The over- expression in these cancers has been targeted with antibodies such as Panitumumab and Cetuximab for imaging modalities. These antibodies can be conjugated with IRDye800 molecules for intraoperative fluorescence imaging or radiolabel for pre-operative positron emission tomography/ computed tomography (PET/CT) imaging. These agents could provide surgeons with additional exams to identify carcinoma in scenarios where only …


"It Says Mommy’S Coffee!": Environmental Print As A Tool To Support Young Children’S Emergent Literacy And Family Engagement In Early Care And Education, Melissa Dawn Sudduth Jan 2025

"It Says Mommy’S Coffee!": Environmental Print As A Tool To Support Young Children’S Emergent Literacy And Family Engagement In Early Care And Education, Melissa Dawn Sudduth

All ETDs from UAB

This study addressed topics related to family engagement in early childhood education, emergent literacy skills, and the use of environmental print (EP) to support young children’s emergent literacy. The children of interest in this study were young children between the ages of birth and 5-years enrolled in licensed, private early care and education (ECE) centers in Alabama. The researcher employed an explanatory sequential mixed methods design using a quantitative survey and qualitative interviews to address the following mixed methods questions: How do families of young children perceive family engagement?, Which emergent literacy skills do families of young children value and …


Sex Differences In The Development Of T-Bet+ B Cells In Lupus, Kathryn A. Sullivan Jan 2025

Sex Differences In The Development Of T-Bet+ B Cells In Lupus, Kathryn A. Sullivan

All ETDs from UAB

Cardinal features of lupus include elevated B cell activation and autoantibody production with a female sex preponderance. Development of T-bet+ B cells, driven by aberrant TLR7 and interferon (IFN) signaling, is a key pathogenic feature of systemic lupus erythematosus (SLE). In the present study, we developed two novel approaches to elucidate the mechanisms of female sex predisposition to lupus. We (i) quantified interactions of sex and genetic variation on the development of autoimmune B-cell phenotypes and autoantibodies in the BXD2 murine model of lupus using a cohort of backcrossed progeny (BXD2 x C57BL/6J) x BXD2; (ii) used a combination approach …


Parsing Clinical And Neurobiological Heterogeneity In First-Episode Psychosis Patients With And Without Features Of The Deficit Syndrome Of Schizophrenia, Matheus Teles Gomes De Araujo Jan 2025

Parsing Clinical And Neurobiological Heterogeneity In First-Episode Psychosis Patients With And Without Features Of The Deficit Syndrome Of Schizophrenia, Matheus Teles Gomes De Araujo

All ETDs from UAB

Schizophrenia is highly heterogeneous in its neurobiological and clinical presentations, which hinders attempts to understand its pathophysiology, limits efforts to identify biomarkers, and deters optimal patient care. A way to parse clinical heterogeneity is to subtype patients based on clinical presentations. The deficit syndrome (DS) is a possible subtype, characterized by primary and enduring negative symptoms. Evidence for neurobiological abnormalities dissociating DS from other forms of schizophrenia is inconsistent as most studies do not account for heterogeneity within patient groups due to limitations of group-level comparisons. The question remains whether DS presents a unique and less heterogeneous neurobiological phenotype. The …


Radioactive Seed Localization For The Resection Of Nonpalpable Breast Lesions, Katherine Ward Jan 2025

Radioactive Seed Localization For The Resection Of Nonpalpable Breast Lesions, Katherine Ward

All ETDs from UAB

Accurate localization of malignant tissues is critical in breast cancer treatment to ensure effective therapy while minimizing damage to surrounding healthy tissues. Radioactive seed localization, specifically using Iodine-125 (I-125), is a prominent method due to its precision and minimally invasive nature. However, this technique poses a risk of radiation exposure to adjacent healthy tissues. This study aims to quantify the radiation dose to healthy breast tissue from I-125 seed implantation by employing two distinct computational approaches: a hemisphere breast model in MATLAB and Monte Carlo simulations in Mathematica. The American Association of Physicists in Medicine (AAPM) Task Group 43 (TG- …


An In-Depth Review Of Food Insecurity In College Students Enrolled In Alabama Historically Black Colleges And Universities, Janice Dansby Washington Jan 2025

An In-Depth Review Of Food Insecurity In College Students Enrolled In Alabama Historically Black Colleges And Universities, Janice Dansby Washington

All ETDs from UAB

Food insecurity is a common issue in the United States (US), and special attention has been given to college students. There is empirical evidence of high food insecurity among African American students at Historically Black Colleges and Universities (HBCUs) (Duke et al., 2023; Dahl et al., 2022; Goldrick-Rab et al., 2018). The current research explores the food-insecure conditions of college students at HBCUs in Alabama, appealing for more studies highlighting the role of all stakeholders in combating this issue. The research questions posed in this study are significant, as they are expected to yield vital information regarding the experiences and …


An Examination Of Sleep Quality And Experimental Pain Sensitivity In People With Hiv And Insomnia, Caroline Kathryn Webb Jan 2025

An Examination Of Sleep Quality And Experimental Pain Sensitivity In People With Hiv And Insomnia, Caroline Kathryn Webb

All ETDs from UAB

Prior research has established a bidirectional relationship between sleep and pain, yet this relationship has been understudied in people living with HIV. The current study investigated the relationship between HIV status (H+/H-) and insomnia status (I+/I-) on sleep and quantitative sensory testing (QST) variables. The study was comprised of two research visits where participants were screened and completed the QST protocol. Participants completed the Insomnia Severity Index (ISI), Dysfunctional Beliefs and Attitudes about Sleep (DBAS), and actigraphy as subjective and objective measures of sleep. There were four groups: H-/I- (n=46), H-/I+ (n=37), H+/I- (n=14), and H+/I+ (n=39) (N=136). Results showed …


Exploring Environmental Health Awareness And Knowledge In 9th – 12th Grade Students: A Mixed Methods Approach, Crystal Stephens Jan 2025

Exploring Environmental Health Awareness And Knowledge In 9th – 12th Grade Students: A Mixed Methods Approach, Crystal Stephens

All ETDs from UAB

EXPLORING ENVIRONMENTAL HEALTH AWARENESS AND KNOWLEDGE IN 9TH – 12TH GRADE STUDENTS: A MIXED METHODS APPROACH CRYSTAL T. STEPHENS ENVIRONMENTAL HEALTH SCIENCES ABSTRACT Safe environments provide accessibility and community protections preventing residents from exposure to contaminants or facing health risks. Unfortunately, environmental exposures such as air pollution and neighborhood-level concerns can adversely impact human health. Environmental justice communities are overburdened with increased adverse environmental exposures and subsequent health disparities. Adolescents may be more vulnerable to exposure risks and provide an opportunity to introduce environmental health education. With their power of peer association and determination, adolescents can influence the health and …


Chronic Pain And Resilience: Associations And Interactions With Diet, Asia Wiggins Jan 2025

Chronic Pain And Resilience: Associations And Interactions With Diet, Asia Wiggins

All ETDs from UAB

Chronic pain is a significant issue globally, affecting millions of people. One relatively new way mechanism to reduce pain is to promote resilience. Yet, the effect of resilience on chronic pain may differ by sociodemographic factors (like racialized group). Furthermore, access to therapies that promote resilience may be limited across populations. However, the utilization of diet interventions for chronic pain symptoms has also been well-examined. In addition, research has shown that diets can be related to psychological resilience. Therefore, beneficial diets could potentially be utilized as a catalyst to, not only promote resilience, but also reduce pain (in combination with …


Prevalence Of Meibomian Gland Dysfunction In A Young Adult Population, Tyler Thomas Jan 2025

Prevalence Of Meibomian Gland Dysfunction In A Young Adult Population, Tyler Thomas

All ETDs from UAB

Background Meibomian gland dysfunction (MGD) varies in prevalence depending on the demographic and can significantly impact quality of life. There is a lack of research on MGD in young adult, professional student populations. Professional students often experience high levels of stress, reduced sleep, and increased electronic device use, which may elevate their risk for developing MGD. Specific Aims This cross-sectional clinical analysis has two specific aims: (1) to determine the prevalence of MGD in a young adult, professional student population, and (2) to identify potential risk factors and clinical assessments correlated with MGD. Methods A total of 147 professional students …


Uncovering The Role Of Heparanase-Armed Extracellular Vesicles In Sepsis-Associated Vascular Endotheliopathy, Robert Patrick Richter Jan 2025

Uncovering The Role Of Heparanase-Armed Extracellular Vesicles In Sepsis-Associated Vascular Endotheliopathy, Robert Patrick Richter

All ETDs from UAB

Sepsis remains one of the most frequent causes of mortality and life-altering morbidity in humans of all ages globally. Though sepsis pathobiology is incompletely understood, it is clear that a unifying feature of all sepsis phenotypes is systemic vascular endotheliopathy and damage to the luminal glycocalyx of endothelial cells, or eGC, that leads to organ injury. While prior work has established that heparan sulfate (HS) is an especially important eGC constituent that helps regulate a host of endothelial cell (EC) functions, its role in promoting endotheliopathy during sepsis has not been fully characterized. Additionally, previous studies in the context of …


December 20, 2024 Ereporter, University Of Alabama At Birmingham Dec 2024

December 20, 2024 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.


December 18, 2024 Blazer Weekly, University Of Alabama At Birmingham Dec 2024

December 18, 2024 Blazer Weekly, University Of Alabama At Birmingham

Blazer Weekly (student newsletter)

No abstract provided.


December 17, 2024 Ereporter, University Of Alabama At Birmingham Dec 2024

December 17, 2024 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.


December 13, 2024 Ereporter, University Of Alabama At Birmingham Dec 2024

December 13, 2024 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.


December 11, 2024 Blazer Weekly, University Of Alabama At Birmingham Dec 2024

December 11, 2024 Blazer Weekly, University Of Alabama At Birmingham

Blazer Weekly (student newsletter)

No abstract provided.


December 10, 2024 Ereporter, University Of Alabama At Birmingham Dec 2024

December 10, 2024 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.


December 6, 2024 Ereporter, University Of Alabama At Birmingham Dec 2024

December 6, 2024 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.


3 Chosen As Uab Vips For Fourth-Quarter 2024, Reporter Staff Dec 2024

3 Chosen As Uab Vips For Fourth-Quarter 2024, Reporter Staff

Browse All News

No abstract provided.


December 4, 2024 Blazer Weekly, University Of Alabama At Birmingham Dec 2024

December 4, 2024 Blazer Weekly, University Of Alabama At Birmingham

Blazer Weekly (student newsletter)

No abstract provided.


Students In Uab's Public Relations Program Win National Teahan Awards, Staff Dec 2024

Students In Uab's Public Relations Program Win National Teahan Awards, Staff

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No abstract provided.


Nsf Epscor Grant Awarded To Uab Professor For Pioneering Quantum Simulation Research, Staff Dec 2024

Nsf Epscor Grant Awarded To Uab Professor For Pioneering Quantum Simulation Research, Staff

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No abstract provided.


Five Tips To Maintain Gut Health During The Holidays, Staff Dec 2024

Five Tips To Maintain Gut Health During The Holidays, Staff

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No abstract provided.


December 3, 2024 Ereporter, University Of Alabama At Birmingham Dec 2024

December 3, 2024 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.


How Giving To Others Can Boost Mental And Physical Health, Staff Dec 2024

How Giving To Others Can Boost Mental And Physical Health, Staff

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No abstract provided.


Chandler & Price Printing Press: Patents From Late 19th To Early 20th Centuries, Ashley S. Mcguire Dec 2024

Chandler & Price Printing Press: Patents From Late 19th To Early 20th Centuries, Ashley S. Mcguire

Patent Coloring Books

Patent coloring book


News From Uab Libraries, 12 2024, Uab Libraries Dec 2024

News From Uab Libraries, 12 2024, Uab Libraries

UAB Libraries News

No abstract provided.


Reframe, Rest And Restart: Understanding Holiday Grief And Coping Mechanisms, Staff Nov 2024

Reframe, Rest And Restart: Understanding Holiday Grief And Coping Mechanisms, Staff

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No abstract provided.


Eleven Quick Tips For Properly Handling Tabular Data, Marla Hertz, Ashley Mcneill Nov 2024

Eleven Quick Tips For Properly Handling Tabular Data, Marla Hertz, Ashley Mcneill

Libraries Professional Work

Proper handling of tabular data, i.e., spreadsheets, is an essential skill for most researchers. Well-curated tabular data has built-in quality control, is machine readable by downstream analysis applications, and ultimately saves researchers’ time. The increased expectation of data sharing grounded by funder and publisher policies has made it even more crucial to format and describe tabular data properly to ensure that it is FAIR—findable, accessible, interoperable, and reusable [1]. However, many researchers are not formally trained in the data management skills necessary to build strong tabular datasets. They may also struggle to anticipate the future needs and potential applications of …


Breaking Down Barriers To Opioid Use Treatment: The Beacon Act Clinic At Uab, Staff Nov 2024

Breaking Down Barriers To Opioid Use Treatment: The Beacon Act Clinic At Uab, Staff

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No abstract provided.