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Articles 4381 - 4410 of 6508
Full-Text Articles in Entire DC Network
Mechanisms Of P53-Mediated Apoptosis, Kelly Lynn Harms
Mechanisms Of P53-Mediated Apoptosis, Kelly Lynn Harms
All ETDs from UAB
No abstract provided.
Nitrite Conversion To Nitric Oxide: Biological Mechanisms And Therapeutic Implications, T Scott Isbell
Nitrite Conversion To Nitric Oxide: Biological Mechanisms And Therapeutic Implications, T Scott Isbell
All ETDs from UAB
No abstract provided.
Quantitative Magnetic Resonance: Validation Of The Echomri 3-In-1 Composition Analyzer, Angela S. Jones
Quantitative Magnetic Resonance: Validation Of The Echomri 3-In-1 Composition Analyzer, Angela S. Jones
All ETDs from UAB
No abstract provided.
Regulation Of Gene Expression In Response To Continuous Low Intensity Direct Current Electrical Fields, Jessica Amber Jennings
Regulation Of Gene Expression In Response To Continuous Low Intensity Direct Current Electrical Fields, Jessica Amber Jennings
All ETDs from UAB
No abstract provided.
Effects Of Pulsed Electromagnetic Stimulation On Cultured Dermal Fibroblasts From Diabetic And Non-Diabetic Rats, Cara Rouse Davis
Effects Of Pulsed Electromagnetic Stimulation On Cultured Dermal Fibroblasts From Diabetic And Non-Diabetic Rats, Cara Rouse Davis
All ETDs from UAB
Diabetes is a disease affecting an increasing number people each year. The medical costs of patients with diabetes are substantial due to the many complications associated with the disease. Dermal wounds are one of these complications and are often very difficult to properly heal. Pulsed Electromagnetic Fields (PEMFs) have been introduced as a method by which to speed the healing of dermal wounds. In this study, a device (provided by Biomet/EBI, Parsippany, NJ) for supplying PEMFs in vitro was used to stimulate dermal fibroblasts, one of the key cells in wound healing. These cells were isolated from the genetically diabetic …
Barrier Membranes For Ridge Augmentation - Is There An Optimal Pore Size?, Rajesh Gutta
Barrier Membranes For Ridge Augmentation - Is There An Optimal Pore Size?, Rajesh Gutta
All ETDs from UAB
Background: - Alveolar bone loss is often a sequelae of edentulism. However, several reconstruction procedures with bone grafts and barrier membranes are used to restore the lost bony architecture. The value of titanium mesh barriers has been shown to be reliable both in vertical and horizontal ridge augmentation procedures. However, there is a paucity of literature supporting the role of pore size of barrier membranes in preventing soft tissue ingrowth during ridge augmentation procedures. There are multiple reports describing a layer of soft tissue with varying thickness beneath the mesh and adhering to the newly regenerated bone. The objective of …
Metal-Tissue Interactions In Early Stage Biocorrosion Of Metallic Stents, Dina Halwani
Metal-Tissue Interactions In Early Stage Biocorrosion Of Metallic Stents, Dina Halwani
All ETDs from UAB
In-vivo corrosion of endovascular stents presents two main risks; release of toxic metallic ions and deterioration of the mechanical properties of the stents which may lead to fracture. Several studies have reported corrosion of nickel-titanium stent wires as well as stainless steel sternal wires. It has been suggested that when corrosion occurs on the surface of implants, an amount of metallic ions equivalent to the corroded volumes is released into surrounding tissue. The purpose of this study was to analyze explanted metallic stents for corrosion. The focus was on the detection of metallic ions released into surrounding vascular tissue as …
Acetylcholinesterase In The Sea Urchin Lytechinus Variegatus : Characterization And Developmental Expression In Larvae, Natalie A. Jennings
Acetylcholinesterase In The Sea Urchin Lytechinus Variegatus : Characterization And Developmental Expression In Larvae, Natalie A. Jennings
All ETDs from UAB
Acetylcholinesterase (AChE) in a deuterostome invertebrate, the echinoid Lytechinus variegatus, has been characterized. Kinetic parameters Vmax, Km, Kss, and b were 453 ± 183 μM ATCh hydrolyzed/minute, 185 ± 11 μM, 308 ± 100 mM, and 0.2, respectively for the substrate acetylthiocholine (ATCh) and 3.1 ± 1.2 μM BTCh hydrolyzed/minute, 654 ± 424 μM, 36 ± 31 mM, and 0.6, respectively for substrate butyrylthiocholine (BTCh). Pharmacologic analyses were performed with four inhibitors of cholinesterases, physostigmine, BW284c51, ethopropazine, and iso-OMPA, and yielded IC50 values of 106 ± 4 nM, 718 ± 118 nM, 2.57 ± 0.6 mM, and > 0.0300 M, respectively. …
Using Genetic Admixture And Lipo Protein Lipase Polymorphisms To Explain Variations In Plasma Triglycerides And High Density Lipoprotein Cholesterol In Premenopauasal African And European American Females, Nihal Omar Natour
All ETDs from UAB
Although African Americans (AA) are well known to be more obese and more in-sulin resistant than European Americas (EA), several studies have shown that AA have lower plasma triglyceride (TG) and higher high density lipoprotein cholesterol (HDL-C). The reasons for these levels of TG and HDL-C are not understood, and scientists have suggested a role of lipoprotein lipase (LPL), a key regulator of TG rich lipoproteins me-tabolism that is also thought to indirectly affect HDL-C metabolism. To investigate the extent to which these observed differences in TG and HDL-C are due to genetic makeup, we investigated the role of genetic …
In Vitro Compressive Fracture Resistance Of The Human Maxillary First Premolar With Different Mod Cavity Design And Restorative Materials, Wen-Chou Wu
All ETDs from UAB
Cuspal failures of MOD (mesial-occlusal-distal) restored teeth have been constantly observed in clinic especially those restored with amalgam. As the pulpal depth and isthmus width of the preparation increases, the strength decreases. A number of studies have investigated the adhesive technique which is intended to increase the fracture resistance by bonding the tooth structure. The results of the studies are controversial because of the differences of research design among studies. The purpose of this study is to evaluate the fracture resistance of the human maxillary first premolar restored with condensable composite (Surefil, Dentsply) and CEREC 3D ProCAD leucite-reinforced ceramic inlays …
Depressive Symptomatology And Suicide Attempts In Adolescents With Mobility Limitations, Ann I. Alriksson-Schmidt
Depressive Symptomatology And Suicide Attempts In Adolescents With Mobility Limitations, Ann I. Alriksson-Schmidt
All ETDs from UAB
Adolescents with mobility limitations may be at increased risk of certain adverse outcomes because of unique or exacerbated pre-existing challenges. The current study examined the relationships among mobility limitations, depressive symptomatology, and suicidal behaviors. Moreover, it was examined if pain and perceived social support mod-erated the relationships between severity of mobility limitations and the three outcome variables, and whether depressive symptomatology mediated the relationships between mobility limitations and suicidal behaviors. Secondary analyses of the AddHealth data set were performed. The sample was 49.18% female, 16.02% African-American, 65.46% Caucasian, 12.20% Hispanic, and 6.33% coded as Other. The mean age was 15.96 …
The Role Of Cd5 In Experimental Autoimmune Encephalitomyelitis, Robert C. Axtell
The Role Of Cd5 In Experimental Autoimmune Encephalitomyelitis, Robert C. Axtell
All ETDs from UAB
The regulation of activation, differentiation and persistence of effector T-cells are critical for the development of Experimental Autoimmune Encephalomyelitis (EAE), the animal model of Multiple Sclerosis. Until now, the function of CD5 was accepted to be a negative regulator of T-cell activation. This dissertation reports that CD5 has an addi-tional role in T-cell responses, which is to promote cell survival. Observations from EAE experiments revealed that mice deficient in CD5 exhibited decreased disease severity which was associated with the inability of activated T-cells to survive. Moreover, block-ing the engagement of CD5 in mice led to enhanced activation induced cell death …
Cd8+ T-Lymphocytes And The Control Of Cytomegalovirus Infection Of The Newborn Central Nervous System, Glenn Robert Burgner Bantug
Cd8+ T-Lymphocytes And The Control Of Cytomegalovirus Infection Of The Newborn Central Nervous System, Glenn Robert Burgner Bantug
All ETDs from UAB
Congenital HCMV infection of the developing brain is the leading viral cause of mental retardation and sensorineural hearing loss. To elucidate the pathogenesis of congenital HCMV CNS infections, we developed a small animal model of CMV infection where newborn Balb/c mice are peripherally inoculated with murine cytomegalovirus. In this model we observed transient deficits in cerebellar/hindbrain development as well as the recruitment of peripheral immune effector cells to the CNS parenchyma. CD8+ T-lymphocytes were the predominant mononuclear cellular infiltrates in the brain and immune-depletion of CD8+ cells resulted in increased viral genome copy numbers in the CNS. CD8+ T-lymphocytes exhibited …
Green Tea Polyphenols Are Associated With Changes In Genetic And Epigenetic Anti-Cancer Mechanisms In Vitro And In Vivo, Joel Bradford Berletch
Green Tea Polyphenols Are Associated With Changes In Genetic And Epigenetic Anti-Cancer Mechanisms In Vitro And In Vivo, Joel Bradford Berletch
All ETDs from UAB
Human chromosomes are protected from degradation associated with cell division by hexameric repeats of 5’-TTAGGG-3’ termed telomeres. During cellular replication human chromosomes undergo the loss of up to 300 bp of DNA with each division, reaching a critical length which leads to senescence and apoptosis. Most cancer cells bypass this lifespan regulatory mechanism by the expression of telomerase, a protein complex that adds telomeres through the reverse transcriptase activity of its catalytic subunit, hTERT. Approximatly 90% of all cancers express the hTERT gene making it an attractive target for novel cancer therapies. The objective of this dissertation was to help …
Impact Of Immunosuppression On The Incidence And Clearance Of Human Papillomavirus In Hiv-Infected Women In Alabama, Madhav P. Bhatta
Impact Of Immunosuppression On The Incidence And Clearance Of Human Papillomavirus In Hiv-Infected Women In Alabama, Madhav P. Bhatta
All ETDs from UAB
Persistent infection with certain “high-risk” types of human papillomavirus (HPV) infection is central to the development of cervical cancer. Human immunodeficiency virus (HIV)-infected women are at a higher risk of HPV infection, high grade cervical intraepithelial lesions, and cervical cancer. This study examined type-specific distribution of prevalent and incident HPV infections, clearance rates, and associated factors using novel molecular assays for HPV detection and genotyping in a cohort of 280 HIVinfected women in Alabama. First, we described the cohort’s sociodemographic characteristics and behavioral risk profile for HIV and other sexually transmitted infections, and assessed the factors associated with HIV-1 viral …
December 18, 2006 Reporter, University Of Alabama At Birmingham
December 18, 2006 Reporter, University Of Alabama At Birmingham
eReporter (campus newsletter)
No abstract provided.
December 4, 2006 Reporter, University Of Alabama At Birmingham
December 4, 2006 Reporter, University Of Alabama At Birmingham
eReporter (campus newsletter)
No abstract provided.
November 20, 2006 Reporter, University Of Alabama At Birmingham
November 20, 2006 Reporter, University Of Alabama At Birmingham
eReporter (campus newsletter)
No abstract provided.
November 6, 2006 Reporter, University Of Alabama At Birmingham
November 6, 2006 Reporter, University Of Alabama At Birmingham
eReporter (campus newsletter)
No abstract provided.
October 16, 2006 Reporter, University Of Alabama At Birmingham
October 16, 2006 Reporter, University Of Alabama At Birmingham
eReporter (campus newsletter)
No abstract provided.
October 2, 2006 Reporter, University Of Alabama At Birmingham
October 2, 2006 Reporter, University Of Alabama At Birmingham
eReporter (campus newsletter)
No abstract provided.
September 18, 2006 Reporter, University Of Alabama At Birmingham
September 18, 2006 Reporter, University Of Alabama At Birmingham
eReporter (campus newsletter)
No abstract provided.
September 4, 2006 Reporter, University Of Alabama At Birmingham
September 4, 2006 Reporter, University Of Alabama At Birmingham
eReporter (campus newsletter)
No abstract provided.
August 21, 2006 Reporter, University Of Alabama At Birmingham
August 21, 2006 Reporter, University Of Alabama At Birmingham
eReporter (campus newsletter)
No abstract provided.
August 7, 2006 Reporter, University Of Alabama At Birmingham
August 7, 2006 Reporter, University Of Alabama At Birmingham
eReporter (campus newsletter)
No abstract provided.
July 24, 2006 Reporter, University Of Alabama At Birmingham
July 24, 2006 Reporter, University Of Alabama At Birmingham
eReporter (campus newsletter)
No abstract provided.
Uab Experts Available To Discuss Back-To-School Topics, Staff
Uab Experts Available To Discuss Back-To-School Topics, Staff
Browse All News
No abstract provided.
July 10, 2006 Reporter, University Of Alabama At Birmingham
July 10, 2006 Reporter, University Of Alabama At Birmingham
eReporter (campus newsletter)
No abstract provided.
June 26, 2006 Reporter, University Of Alabama At Birmingham
June 26, 2006 Reporter, University Of Alabama At Birmingham
eReporter (campus newsletter)
No abstract provided.
June 12, 2006 Reporter, University Of Alabama At Birmingham
June 12, 2006 Reporter, University Of Alabama At Birmingham
eReporter (campus newsletter)
No abstract provided.