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Articles 2881 - 2910 of 6508
Full-Text Articles in Entire DC Network
Sex Differences In Ss-Adrenergic Responsiveness Of Isolated Rabbit Hearts, Gregory Hoeker
Sex Differences In Ss-Adrenergic Responsiveness Of Isolated Rabbit Hearts, Gregory Hoeker
All ETDs from UAB
Stimulation of adrenergic receptors by catecholamines is the predominant regulatory mechanism for cardiovascular performance. Many cardiovascular diseases involve changes in ß-adrenergic signaling that often lead to decreased cardiac performance, cardiac arrhythmias, and/or sudden cardiac death. This has made ß-adrenergic receptors (ß-ARs) a significant therapeutic target in cardiovascular disease. Sex differences in ß-adrenergic responsiveness have been associated with cardioprotection in females, conferring a survival benefit in female patients with heart failure (HF). The heart contains three distinct ß-ARs: ß1-, ß2-, and ß3-AR. It is not known how each ß-AR subtype contributes to the sex differences in ß-responsiveness, let alone how this …
Effect Of Protons On The Biology Of Human Gliomas, Avinash Vinayak Honasoge
Effect Of Protons On The Biology Of Human Gliomas, Avinash Vinayak Honasoge
All ETDs from UAB
Gliomas are the most common and most deadly primary brain cancer. Patient outcome for the most malignant variety, the World Health Organization (WHO) Type IV glioblastoma multiforme (GBM), has stagnated over the last several decades - the best combination treatment of surgical resection, radiation, and chemotherapy results in median survival of just over a year. To escape treatment, GBM must multiply and migrate in a confined brain environment. Both of these aspects of tumor cell invasion rely on the cell's ability to volume regulate; cell division involves a stage called "pre-mitotic condensation" in which the cells shrink immediately prior to …
Nanodiamond Mediated Therapies For Prostate Cancer, Amanee Salaam
Nanodiamond Mediated Therapies For Prostate Cancer, Amanee Salaam
All ETDs from UAB
Enhancing therapeutic efficacy is essential for successful treatment of chemoresistant cancers such as metastatic hormone-refractory prostate cancer. Current chemotherapy regimens are plagued with issues such as toxicity, low bioavailability, and lack of specificity. To combat these issues, the feasibility of using nanodiamond particles (ND) to enhance the therapeutic efficacy of doxorubicin and resveratrol was investigated. The enhancement of chemotherapy using NDs was evaluated with three unique approaches: (1) drug mediation, (2) combination therapy, and (3) targeted drug delivery. The ND mediated doxorubicin system achieved a 50% improvement in therapeutic efficacy with over 60% cell death. The ND resveratrol combination therapy …
Role Of Immunoregulatory Cytokines Il-12 And Il-23 In Skin Cancer, Tahseen H. Nasti
Role Of Immunoregulatory Cytokines Il-12 And Il-23 In Skin Cancer, Tahseen H. Nasti
All ETDs from UAB
The incidence of new cases of skin cancer, which includes non-melanoma epithelial tumors and melanoma, has increased dramatically over the last few decades. Approximately 75% of all skin cancer-related deaths is due to melanoma, which is one of the most aggressive and difficult cancers to treat. The initiating events and mechanisms that influence melanoma development are not fully known, due in part to a paucity of animal models amenable to identifying new oncogenic mutations, and investigating mechanisms of immunosurveillance. Transgenic mouse models often harbor an activating mutation in a known oncogene in all somatic cells, and its widespread expression from …
Dihydrofolate Reductase Inhibitors - Applications To Chagas Disease And Dental Caries, Thao Nguyen
Dihydrofolate Reductase Inhibitors - Applications To Chagas Disease And Dental Caries, Thao Nguyen
All ETDs from UAB
significantly influenced sex ratios by increasing the production of males when
Coevolution Of Sponges And Microbial Symbionts Across Ocean Basins, Zachary Lee Nolen
Coevolution Of Sponges And Microbial Symbionts Across Ocean Basins, Zachary Lee Nolen
All ETDs from UAB
Sponges (phylum Porifera) can comprise a large portion of benthic communities in freshwater and marine environments. Because sponges possess simple body plans and can have substantial phenotypic plasticity within species, reconstructing phylogenies of Porifera based upon morphologies alone has proven difficult. With the advent of nucleic acid sequencing technologies, interest in sponge phylogenetics has significantly increased among researchers. Additionally, sponges host a wide range of microbial symbionts, including the cyanobacterium Synechococcus spongiarum. This study examined the evolution of both sets of organisms in the symbiotic relationship between Aplysina sponges and Synechococcus cyanobacteria. In Chapter 3, gene sequences coding for the …
Three-Dimensional Photography Of Facial Morphology Of African-American Children Compared To Welsh Children, Don Franklin Norris
Three-Dimensional Photography Of Facial Morphology Of African-American Children Compared To Welsh Children, Don Franklin Norris
All ETDs from UAB
The purpose of this study is to compare the facial morphology of African-American children to Welsh children using three-dimensional imaging. Materials and Methods: Three-dimensional images were captured using a stereo-photogrammatic camera system (3dMDfaceTM). 107 African-American children were imaged with the 3dMDfaceTM system and were compared with 64 Welsh children which were previously imaged using two Minolta Vivid VI900 3D laser scanners arranged in a stereo pair. The subjects were between 10 and 13 years old, presented with a normal BMI, and had no major craniofacial deformity. The images were aligned, combined and averaged using Rapidform 2006 Plus Pack 2 software …
December 20, 2013 Ereporter, University Of Alabama At Birmingham
December 20, 2013 Ereporter, University Of Alabama At Birmingham
eReporter (campus newsletter)
No abstract provided.
Newly Identified Immune Receptor May Activate B Cells In Autoimmunity, Greg Williams
Newly Identified Immune Receptor May Activate B Cells In Autoimmunity, Greg Williams
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No abstract provided.
Committee Releases New Guideline For Management Of High Blood Pressure, Tyler Greer
Committee Releases New Guideline For Management Of High Blood Pressure, Tyler Greer
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No abstract provided.
Newly Identified Immune Receptor May Activate B Cells In Autoimmunity, Jim Bakken
Newly Identified Immune Receptor May Activate B Cells In Autoimmunity, Jim Bakken
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No abstract provided.
Faculty Become Students To Learn Simulation Training, Clinton Colmenares
Faculty Become Students To Learn Simulation Training, Clinton Colmenares
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No abstract provided.
First Mechanism-Based Drug Design Underway In Kidney Disease, Jim Bakken
First Mechanism-Based Drug Design Underway In Kidney Disease, Jim Bakken
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No abstract provided.
First Mechanism-Based Drug Design Underway In Kidney Disease, Greg Williams
First Mechanism-Based Drug Design Underway In Kidney Disease, Greg Williams
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No abstract provided.
Uab Commencement Scheduled For Dec. 14, Staff
Henry Hoffman, Long-Time Supporter For Uab, Dies At 91, Clinton Colmenares
Henry Hoffman, Long-Time Supporter For Uab, Dies At 91, Clinton Colmenares
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No abstract provided.
Uab Names New Chair Of Biology, Jim Bakken
Uab Unveils State's Largest, Most Advanced Nuclear Magnetic Resonance Facility, Jim Bakken
Uab Unveils State's Largest, Most Advanced Nuclear Magnetic Resonance Facility, Jim Bakken
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No abstract provided.
December 3, 2013 Ereporter, University Of Alabama At Birmingham
December 3, 2013 Ereporter, University Of Alabama At Birmingham
eReporter (campus newsletter)
No abstract provided.
College Of Arts And Sciences Names Two Department Chairs, Natalie Wade
College Of Arts And Sciences Names Two Department Chairs, Natalie Wade
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No abstract provided.
November 26, 2013 Ereporter, University Of Alabama At Birmingham
November 26, 2013 Ereporter, University Of Alabama At Birmingham
eReporter (campus newsletter)
No abstract provided.
New Nuclear Magnetic Imaging Will Propel Drug Development, Clinton Colmenares
New Nuclear Magnetic Imaging Will Propel Drug Development, Clinton Colmenares
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No abstract provided.
November 22, 2013 Ereporter, University Of Alabama At Birmingham
November 22, 2013 Ereporter, University Of Alabama At Birmingham
eReporter (campus newsletter)
No abstract provided.
Biology's Mcclintock To Speak At Annual Dinner, Staff
Biology's Mcclintock To Speak At Annual Dinner, Staff
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No abstract provided.
Biology's Warner Receives National Bartholomew Award, Staff
Biology's Warner Receives National Bartholomew Award, Staff
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No abstract provided.
November 19, 2013 Ereporter, University Of Alabama At Birmingham
November 19, 2013 Ereporter, University Of Alabama At Birmingham
eReporter (campus newsletter)
No abstract provided.
Exercise Medicine Symposium Works Out Research, Clinton Colmenares
Exercise Medicine Symposium Works Out Research, Clinton Colmenares
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No abstract provided.
Phun Week Brings Science, Health To Life, Kendra Carter
Phun Week Brings Science, Health To Life, Kendra Carter
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No abstract provided.
Biology's Warner Recognized For Distinguished Contributions, Linda Gunter
Biology's Warner Recognized For Distinguished Contributions, Linda Gunter
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No abstract provided.
Ms Society Visits Uab Labs, Clinton Colmenares