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History Of Allergy, Atopy, Infectious And Autoimmune Disease And Risk Of Multiple Myeloma, Tony B. Zbysinski Jan 2022

History Of Allergy, Atopy, Infectious And Autoimmune Disease And Risk Of Multiple Myeloma, Tony B. Zbysinski

All ETDs from UAB

Multiple Myeloma (MM) is a plasma cell malignancy, which is defined in part by antibodies and complexes of immunoglobulin (Ig) heavy and light chains (IgH and IgL). Previous associations of immune-stimulating conditions such as allergic, autoimmune, and infectious conditions and the risk of multiple myeloma (MM) are inconsistent. However, these studies were conducted in populations of European ancestry, leaving the possibility that these conditions may contribute to the excess risk of plasma cell proliferative disorders observed among Black Americans. Therefore, we assessed MGUS, a precursor condition to myeloma, and MM risk related to a history of allergy, atopy, infections and …


Telehealth High-Intensity Interval Exercise And Cardiometabolic Health In Spinal Cord Injury, Jacob Adams Jan 2022

Telehealth High-Intensity Interval Exercise And Cardiometabolic Health In Spinal Cord Injury, Jacob Adams

All ETDs from UAB

BACKGROUND: Recent studies have shown that high intensity interval training (HIIT) can improve cardiometabolic health in individuals with spinal cord injury (SCI). Individuals with SCI experience a wide array of barriers to participate in exercise such as lack of time, accessible equipment, and transportation. It is imperative to identify modes of exercise that provide effective health benefits and are accessible while requiring low time commitment. Studies have demonstrated that HIIT has similar positive improvements in cardiometabolic health with 20% of total time commitment compared to moderate intensity exercise (MIT) in short term studies. OBJECTIVES: The purpose of this study is …


Instructional Leadership During Modern Crises: A Phenomenological Study Of A Pandemic In The Modern Age, Larry Bradley Robertson Jan 2022

Instructional Leadership During Modern Crises: A Phenomenological Study Of A Pandemic In The Modern Age, Larry Bradley Robertson

All ETDs from UAB

Significant research exists concerning crisis management in schools; however, educational leaders were unprepared for the COVID-19 pandemic (Bratianu & Bejinaru, 2021; Diliberti et al., 2020; Tomasik et al., 2020). This crisis was different from any experienced in modern times. It impacted the entire world in terms of politics, economics, education, and way of life. New issues emerged due to the necessity for schools to implement remote learning. Among those issues were online learning, the disparity of the haves and have nots among students, social and emotional well-being of students, learning loss, and the role of the educator (Martinez & Broemmel, …


The Requirement Of Transcriptional Lim Complex Co-Regulators For Pancreatic Endocrine Cell Development And Function, Eliana Davi Toren Jan 2022

The Requirement Of Transcriptional Lim Complex Co-Regulators For Pancreatic Endocrine Cell Development And Function, Eliana Davi Toren

All ETDs from UAB

The prevalence and tremendous impact of diabetes mellitus has made glucose regulation of the insulin-producing -cell and surrounding pancreatic islet of Langerhans a center of public and research interests alike. A comprehensive understanding of these hormone-producing cells begins with their developmental origins. What are the genetic cues and participants in the tightly orchestrated process of their formation? Investigating the earliest determinants of islet-cell fate not only allows us to deeply understand mature - and islet-cell function, but also produces a data-driven template for how these cells can be reproduced in future stem-cell based diabetes therapies. LIM transcriptional complexes are indispensable …


Examining Family Health Through Family-Centered Care Within An Organizational Context, Bria Kathryn Morgan Jan 2022

Examining Family Health Through Family-Centered Care Within An Organizational Context, Bria Kathryn Morgan

All ETDs from UAB

Introduction: Family health is characterized as a multi-dimensional process that is shaped by a number of social determinants. Similar to individual health, various domains work in conjunction and intersect to produce family health. Family-centered care is one of the many ways that healthcare providers can support health, however, little is known about if and how it is beneficial for family health. Considering the relevance of an organizational context, this study seeks to understand the delivery of care within an organization and providers’ perceptions of family-centered care. Data/Methods: Using the case of the Ronald McDonald House, this study integrates qualitative content …


Nutrition Practices And Body Composition In Infants Born Preterm, Maggie Jerome Jan 2022

Nutrition Practices And Body Composition In Infants Born Preterm, Maggie Jerome

All ETDs from UAB

Adequate nutrition and optimal growth are critical goals of clinical care for premature infants in the NICU due to rapid brain growth and development that occur during this time. Emerging evidence suggests that body composition in preterm infants is predictive of neurodevelopmental and metabolic outcomes later in childhood. The objective of this dissertation is to investigate factors affecting premature infant growth and body composition, including high enteral protein supplementation, nutrition during the first two weeks of life, and race of infants born at 22-32 weeks gestational age admitted to the UAB NICU. In a pilot study, 56 preterm infants were …


Exploring The Influence Of Psychosocial Stress And Inflammatory Properties Of The Diet On Cardiometabolic Risk And Gut Microbiome Health Among Young Adult Women Of Birmingham, Alabama, Rachel Olivia Knight Jan 2022

Exploring The Influence Of Psychosocial Stress And Inflammatory Properties Of The Diet On Cardiometabolic Risk And Gut Microbiome Health Among Young Adult Women Of Birmingham, Alabama, Rachel Olivia Knight

All ETDs from UAB

Concerning trends for obesity, diabetes, heart attacks, and obesity-related cancers, or cardiometabolic disease (CMD), are developing within the emerging and young adult/adulthood (EYA) population. Evidence supports the concept that chronic stress leads to physiologic dysregulation, reduced mental health, chronic diseases, and reduced longevity; however, these are not inevitable outcomes, and resilience or vulnerability is determined by interacting environmental and biobehavioral factors. Although CMD manifests clinically in older adulthood, disease pathophysiology begins earlier, and thus, EYA is a critical time for observation and intervention. Growing evidence indicates inflammation is a major risk factor in CMD development and may be exacerbated by …


Health Disparities In Cardiometabolic Risk Among African American And European American Adults, Catharine A. Couch Jan 2022

Health Disparities In Cardiometabolic Risk Among African American And European American Adults, Catharine A. Couch

All ETDs from UAB

African American (AA) individuals are disproportionately burdened by cardiometabolic disease, including type 2 diabetes (T2D) and cardiovascular disease (CVD), and associated risk factors. The objective of this dissertation research was to investigate pathophysiological and lifestyle contributors to racial disparities in cardiometabolic disease including beta-cell dysfunction, ectopic fat, the natriuretic peptide system, and diet. These first three risk factors, beta-cell dysfunction, ectopic fat, and the natriuretic peptide system, were explored in a cross-sectional study of young AA and European American (EA) adults. The fourth risk factor, diet, was explored in a large, national cohort of black and white adults. First, we …


Il-22 Mediated Host Defense During Attaching-Effacing Pathogen Infection, Baiyi Cai Jan 2022

Il-22 Mediated Host Defense During Attaching-Effacing Pathogen Infection, Baiyi Cai

All ETDs from UAB

Intestinal infections are a cause of morbidity and mortality worldwide and remain a public threat. Interleukin (IL)-22 is central to host immune responses in the intestine during infection and inflammation. IL-22 can be produced by both innate and adaptive immune cells, yet their relative contributions to host protection remain unclear. Here we demonstrated the specific role and mechanism for IL-22 from innate and adaptive sources to protect the host. Using the Citrobacter rodentium (C.r) model, we found that IL-22 from innate cell, protect the host during early infection. IL-22 induces epithelial production of polymorphonuclear neutrophils (PMN) recruiting chemokine CXCL1, CXCL2 …


Self-Efficacy In Pulmonary Rehabilitation, Erica Anderson Jan 2022

Self-Efficacy In Pulmonary Rehabilitation, Erica Anderson

All ETDs from UAB

the fourth leading cause of death in the United States, Chronic Obstructive Pulmonary Disease (COPD) is a major contributor of morbidity and mortality. The disease is characterized by chronic irritation and inflammation of the airways. The most common symptoms include chronic cough and shortness-of-breath. Pulmonary rehabilitation is a comprehensive exercise and education program for people with lung disease. It is well-established as an intervention to improve symptoms and other qualityof- life outcomes in people with COPD. Self-efficacy is the belief in one’s own abilities. It is recognized by the American Thoracic Society and European Respiratory Society as an integral part …


Distinct Clinical Manifestations Associated With Autoantibodies And Cytokines In Systemic Lupus Erythematosus, Fatima K. Alduraibi Jan 2022

Distinct Clinical Manifestations Associated With Autoantibodies And Cytokines In Systemic Lupus Erythematosus, Fatima K. Alduraibi

All ETDs from UAB

Objective: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by production of autoantibodies (autoAbs) and cytokines. Moreover, lupus nephritis (LN) occurs in approximately 50% of SLE patients. AutoAb and cytokine levels produced by B and T cells are high in LN patients, although their relationship with histological patterns requires investigation. Methods: We analyzed the relationship between B cell cytokines and major T cell cyto-kines, including their association with autoAbs, and the clinical manifestations of SLE, especially LN. We also analyzed endogenous intracellular interferon beta (IFNβ) expression in the peripheral blood mononuclear cells and serum circulating nephritogenic autoAbs from …


This Long-Running Study Proves That Nice People Finish First, Matt Windsor Dec 2021

This Long-Running Study Proves That Nice People Finish First, Matt Windsor

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No abstract provided.


November 23, 2021 Ereporter, University Of Alabama At Birmingham Nov 2021

November 23, 2021 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.


The Science Behind Cooking A Delicious Thanksgiving Meal, Adam Pope Nov 2021

The Science Behind Cooking A Delicious Thanksgiving Meal, Adam Pope

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No abstract provided.


Diabetes Prevention: Take Control Of Your Health With These Simple Tips, Staff Nov 2021

Diabetes Prevention: Take Control Of Your Health With These Simple Tips, Staff

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No abstract provided.


November 12, 2021 Ereporter, University Of Alabama At Birmingham Nov 2021

November 12, 2021 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.


November 10, 2021 Greenmail, University Of Alabama At Birmingham Nov 2021

November 10, 2021 Greenmail, University Of Alabama At Birmingham

GreenMail (student newsletter through 2024)

No abstract provided.


Live Healthsmart, Bundles Of Hope Diaper Bank Partner To Provide Community With Affordable Produce And Free Diapers, Staff Oct 2021

Live Healthsmart, Bundles Of Hope Diaper Bank Partner To Provide Community With Affordable Produce And Free Diapers, Staff

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No abstract provided.


New Research Faculty Introduction, Emily Liming Johns Oct 2021

New Research Faculty Introduction, Emily Liming Johns

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No abstract provided.


Uab Trial Studying Diet Composition - With No Weight Loss - To Treat Type 2 Diabetes, Matt Windsor Sep 2021

Uab Trial Studying Diet Composition - With No Weight Loss - To Treat Type 2 Diabetes, Matt Windsor

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No abstract provided.


Vickers Interviews Asif On 'The Checkup' For National Wellness Month, Erin Slay-Wilson Aug 2021

Vickers Interviews Asif On 'The Checkup' For National Wellness Month, Erin Slay-Wilson

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No abstract provided.


Why Doesn't Weight Loss Work For Me? Smarter Studies Aim For Faster Answers, Staff Aug 2021

Why Doesn't Weight Loss Work For Me? Smarter Studies Aim For Faster Answers, Staff

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No abstract provided.


Garvey Selected To Earn Highest Honor From Aace, Staff Aug 2021

Garvey Selected To Earn Highest Honor From Aace, Staff

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No abstract provided.


Why Doesn't Weight Loss Work For Me? Smarter Studies Aim For Faster Answers., Matt Windsor Aug 2021

Why Doesn't Weight Loss Work For Me? Smarter Studies Aim For Faster Answers., Matt Windsor

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No abstract provided.


August 4, 2021 Greenmail, University Of Alabama At Birmingham Aug 2021

August 4, 2021 Greenmail, University Of Alabama At Birmingham

GreenMail (student newsletter through 2024)

No abstract provided.


August 2, 2021 Ereporter, University Of Alabama At Birmingham Aug 2021

August 2, 2021 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.


July 30, 2021 Ereporter, University Of Alabama At Birmingham Jul 2021

July 30, 2021 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.


$20m Awarded For Scientific Research To Ensure Health Equity In Preventing Hypertension, Alicia Rohan Jul 2021

$20m Awarded For Scientific Research To Ensure Health Equity In Preventing Hypertension, Alicia Rohan

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No abstract provided.


Second-Career Ms2s Learn From Oncology And Survivorship Expert Through Cares; Use Prior Experience To Guide Current Research, Mary Ashley Canevaro Jul 2021

Second-Career Ms2s Learn From Oncology And Survivorship Expert Through Cares; Use Prior Experience To Guide Current Research, Mary Ashley Canevaro

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No abstract provided.


Samuel Named First-Place Graduate Winner At The Minority Student Research Symposium, Staff Jul 2021

Samuel Named First-Place Graduate Winner At The Minority Student Research Symposium, Staff

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No abstract provided.