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Diagnosis And Screening Of Autism Spectrum Disorder In Clinical Populations, Jenna Brooke Lebersfeld Jan 2020

Diagnosis And Screening Of Autism Spectrum Disorder In Clinical Populations, Jenna Brooke Lebersfeld

All ETDs from UAB

Screening and diagnosis of children with autism spectrum disorder (ASD) are crucial for these individuals to receive appropriate ASD-focused intervention as early as possible. Using ASD-specific strategies in early intervention leads to improvement across skill areas. The Autism Diagnostic Observation Schedule, Second Edition (ADOS-2) and the Autism Diagnostic Interview, Revised (ADI-R) are two gold-standard diagnostic instruments used in comprehensive ASD evaluations. These measures have high accuracy in research settings, but evidence of accuracy in clinical settings is less robust. They also require significant training and expertise to administer, and comprehensive ASD evaluations are in high demand. Therefore, it is important …

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Clinical Evaluation Of The Temporomandibular Joint Function Using 4d Jaw Tracking Following Total Joint Replacement, Farhana Rahman Jan 2020

Clinical Evaluation Of The Temporomandibular Joint Function Using 4d Jaw Tracking Following Total Joint Replacement, Farhana Rahman

All ETDs from UAB

The degenerative temporomandibular joint diseases such as osteoarthritis, rheumatic arthritis, TMJ ankylosis, condylar resorption is successfully treated by total joint replacement. The aim of this study was to examine the function of Temporomandibular joint after total joint replacement. 15 patients with unilateral or bilateral TMJ total joint replacements and 15 healthy controls were evaluated via SICAT JMT+ device. This non-invasive system measures 3D position and rotation in all degrees of freedom and allows undisturbed functional mandibular movements to provide a quantitative evaluation. In addition, a TMJ questionnaire consisting the subjective symptoms was also obtained. Mandibular movements after total joint replacements …

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Exploring The Physical And Mental Health Disparities In The Transgender Male Community In A Southern Community-Based Medical Lgbtq Organization, Karen E. Musgrove Jan 2020

Exploring The Physical And Mental Health Disparities In The Transgender Male Community In A Southern Community-Based Medical Lgbtq Organization, Karen E. Musgrove

All ETDs from UAB

This dissertation examined the physical and mental health disparities in the transgender male community in a Southern community-based medical LGBTQ (lesbian, gay, bisexual, transgender, queer) organization via a convergent mixed methods study design. There is a paucity of research on the transgender male community in terms of their physical and mental health care needs, services, and disparities. Quantitative data were col-lected via a chart review of 130 transgender male medical charts at the Magic City Well-ness Center (MCWC). The MCWC transgender male medical chart data were compared to three groups separately of the 2018 Behavioral Risk Factor Surveillance System (BRFSS) …

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Neurobiological Signatures Of Treatment Response – A Multi-Modal Study In Schizophrenia, Eric A. Nelson Jan 2020

Neurobiological Signatures Of Treatment Response – A Multi-Modal Study In Schizophrenia, Eric A. Nelson

All ETDs from UAB

Schizophrenia is a heterogeneous mental illness and even though it has been studied for over a century, the neuropathology of the disease is still not fully under-stood. Only 1/3 of patients respond well to antipsychotic drug (APD) treatment while another 1/3 show only a partial response and yet another 1/3 of patients are non-responsive, exhibiting little to no change in positive symptoms and a general reduction in quality of life. In order to develop treatments that better serve non-responding and partial re-sponse patients, a greater understanding of APD neuromechanisms is needed. In order to provide a more comprehensive assessment of …

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Genetic And Immunologic Predictors Of Genital Chlamydia Reinfection In African American Women Using Bayesian Hierarchical Models, Kristin Olson Jan 2020

Genetic And Immunologic Predictors Of Genital Chlamydia Reinfection In African American Women Using Bayesian Hierarchical Models, Kristin Olson

All ETDs from UAB

Chlamydia trachomatis (CT) infection is the most common sexually transmitted infec-tion. The burden is greatest in young, African American women. CT reinfections are common and increase risk for reproductive morbidity. Why some women are more sus-ceptible to reinfection is not well understood. Emerging evidence suggests immunologic and genetic variants may predict reinfection susceptibility. The primary goal of this dissertation is to evaluate immunologic and genetic vari-ants as predictors of CT reinfection in young, African American women using different modeling approaches, which has never been reported previously. To evaluate a much larger number of potential predictors than our sample size (a …

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Examining The Impact Of Baldrige On Hospital Performance, Jennifer O. Strahan Jan 2020

Examining The Impact Of Baldrige On Hospital Performance, Jennifer O. Strahan

All ETDs from UAB

The national Baldrige program has supported performance excellence within healthcare for over twenty years, yet it has seen recent declines in the number of applications despite Baldrige award recipients claiming noteworthy improvements across operational, clinical, and financial outcomes. Previous studies have compared Baldrige hospital recipients to non-recipients, but no studies have empirically investigated the value of pursuing the Baldrige award, regardless of award recognition or not. Furthermore, it is unclear if specific categories of the Baldrige Excellence Framework (BEF) are associated with standardized industry performance outcomes. This study used propensity score matching with linear and quantile regression techniques to understand …

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Circadian Clock And Lipid Metabolism Disruption In Fatty Liver Disease, Jennifer Valcin Jan 2020

Circadian Clock And Lipid Metabolism Disruption In Fatty Liver Disease, Jennifer Valcin

All ETDs from UAB

Hepatic Steatosis, characterized by the accumulation of triglyceride (TG) in the liver is the first stage of Alcoholic Liver Disease (ALD) and Nonalcoholic Fatty Liver Disease (NAFLD). Many metabolic pathways, including lipid metabolism, are regulated by the molecular circadian clock. Importantly, alcohol consumption and obesity induce circadian clock disruption, a risk factor for many diseases, including liver disease. In our first study, we investigated the combined effect of clock disruption and alcohol feeding on liver pathology, and diurnal rhythms in the liver molecular clock and lipid metabolism. Male liver-specific Bmal1 knockout (LKO) mice and control littermates were fed a control …

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Resonance Frequency Bifurcation Based Passive Wireless Sensor Interface Design For Multi-Parameters And Differentially Monitoring, Xinlei Yang Jan 2020

Resonance Frequency Bifurcation Based Passive Wireless Sensor Interface Design For Multi-Parameters And Differentially Monitoring, Xinlei Yang

All ETDs from UAB

Many wireless and passive sensors are developed and used in various fields with the growth of Internet-of-Things, IoT, and biomedical technologies. These sensors can measure physical parameters such as temperature, pressure, displacement, etc. These parameters can be converted into corresponding changes in resistance, capacitance, and inductance, and captured by LC tank-based sensors, wirelessly. The passive LC tank-based sensors can only measure a single parameter. By proposing a new technology, multi-resonance sensing mechanism, for measuring multiple parameters differentially in this work. Based on the proposed technology, two sensing systems have been designed and implemented. 1) Estimating human walking gait speed by …

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Dna Methylation: A Mechanism For Sustained Alteration Of Kir4.1 Expression Following Central Nervous System Insult, Jessica Boni Jan 2020

Dna Methylation: A Mechanism For Sustained Alteration Of Kir4.1 Expression Following Central Nervous System Insult, Jessica Boni

All ETDs from UAB

Astrocytes are the most numerous cells in the brain and play a critical role in maintaining homeostatic extracellular potassium ([K+]e). Maintaining low [K+]e is essential for many cellular functions including maintenance of intensely negative resting membrane potentials in the central nervous system. This process is mediated, in part, by a glial-specific, inwardly rectifying potassium channel, Kir4.1. Underscoring the role of Kir4.1 in CNS functioning, genetic mutations in Kcnj10, the gene which encodes Kir4.1, causes seizures, ataxia and developmental disability in humans. Notably, loss of Kir4.1 protein and mRNA are consistently observed after CNS injury, and in a number of neurological …

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Development Of Mitochondrial-Targeted Genetic Tools To Investigate How Changes In Mitochondrial Function Affect The Heart, Patrick James Ernst Jan 2020

Development Of Mitochondrial-Targeted Genetic Tools To Investigate How Changes In Mitochondrial Function Affect The Heart, Patrick James Ernst

All ETDs from UAB

Mitochondria are an important organelle found in all human cells, they fulfill several crucial roles necessary for cellular function such as energy production, calcium handling, metabolic regulation, and inducing pre-programmed cell death. Mitochondrial dysfunction is associated with many different diseases such as heart failure, aging, and cancer, as well as multiple neurodegenerative diseases. While there are currently different tools and approaches for studying different aspects of both mitochondrial function and dysfunction, they tend to have major drawbacks that limit their practicality and conclusions that can be drawn using them. We hypothesized that by finding the correct genetic mitochondrial targeting sequence, …

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Evolution Of Growth Rates And Interspecies Interactions Of Prochlorococcus And Alteromonas Under Ocean Acidification Conditions, Matthew Kuhl Jan 2020

Evolution Of Growth Rates And Interspecies Interactions Of Prochlorococcus And Alteromonas Under Ocean Acidification Conditions, Matthew Kuhl

All ETDs from UAB

Prochlorococcus is an unusually small and numerous genus of marine cyanobacteria which is thought to contribute 8.5% of marine primary production. Prochlorococcus lacks a gene for catalase, resulting in significant sensitivity to stress from reactive oxygen species (ROS), particularly hydrogen peroxide. Prochlorococcus is known to rely on other species of microbes in the ocean to degrade ROS, such as Alteromonas, a heterotrophic “helper” bacterium with which it is frequently co-located. However, it has been observed that Y2100 predicted ocean acidification conditions (800 ppm atmospheric CO2) reduce catalase production by Alteromonas strain EZ55, increasing oxidative stress on Prochlorococcus strain MIT 9312. …

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Mountains, Mines, And Quarters: Life, Labor, And The Sloss-Sheffield Steel & Iron Company, 1880-1950, Steven Filoromo Jan 2020

Mountains, Mines, And Quarters: Life, Labor, And The Sloss-Sheffield Steel & Iron Company, 1880-1950, Steven Filoromo

Vulcan Historical Review

pp. 23-33

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Mama Always Warned They Still Hate The Jews, Abriana Jette Jan 2020

Mama Always Warned They Still Hate The Jews, Abriana Jette

Nelle (literary magazine)

pp. 51-52

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On The Burial Of Pecola Breedlove And Finding Voice Through Toni Morrison, Jessie Lafrance Dunbar Jan 2020

On The Burial Of Pecola Breedlove And Finding Voice Through Toni Morrison, Jessie Lafrance Dunbar

Nelle (literary magazine)

pp. 53-58

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Vulcan Historical Review 24 (End Matter), Vulcan Historical Review Staff Jan 2020

Vulcan Historical Review 24 (End Matter), Vulcan Historical Review Staff

Vulcan Historical Review

No abstract provided.

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Sieve, Eamon Grennan Jan 2020

Sieve, Eamon Grennan

Birmingham Poetry Review

p. 114

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49 Xxxxy Klinefelter Syndrome, Jennifer Lamar, Janaki Nimmagadda, Clinton Martin, Katherine Moody Jan 2020

49 Xxxxy Klinefelter Syndrome, Jennifer Lamar, Janaki Nimmagadda, Clinton Martin, Katherine Moody

UAB Huntsville Research Day - All Presentations

2020 clinical vignette poster

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"On Heparin With Thrombocytopenia, Must Be Heparin Induced Thrombocytopenia," – Think Again., Sabrina Matosz, Ali Hachem, Farrah Ibrahim Jan 2020

"On Heparin With Thrombocytopenia, Must Be Heparin Induced Thrombocytopenia," – Think Again., Sabrina Matosz, Ali Hachem, Farrah Ibrahim

UAB Huntsville Research Day - All Presentations

2020 clinical vignette poster

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A Case Of The Human Metapneumovirus, Joseph Shaw, Qurrat-Ul-Ain Aziz, Ali Hassoun Jan 2020

A Case Of The Human Metapneumovirus, Joseph Shaw, Qurrat-Ul-Ain Aziz, Ali Hassoun

UAB Huntsville Research Day - All Presentations

2020 clinical vignette poster

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Enterococcal Bacteremia Is More Common Than You Think, Joseph Shaw, Qurrat-Ul-Ain Aziz, Ali Hassoun Jan 2020

Enterococcal Bacteremia Is More Common Than You Think, Joseph Shaw, Qurrat-Ul-Ain Aziz, Ali Hassoun

UAB Huntsville Research Day - All Presentations

2020 clinical vignette poster

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Herpes Esophagitis Can Resemble Candidiasis, Swetha Srialluri, Ali Hassoun, Martha Anna Chodaba Jan 2020

Herpes Esophagitis Can Resemble Candidiasis, Swetha Srialluri, Ali Hassoun, Martha Anna Chodaba

UAB Huntsville Research Day - All Presentations

2020 clinical vignette poster

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Is It Getting Hot In Here? – A Case Of Multiorgan Failure And Dic In Heat Stroke, Katherine E. Glosemeyer, William Humphrey Jan 2020

Is It Getting Hot In Here? – A Case Of Multiorgan Failure And Dic In Heat Stroke, Katherine E. Glosemeyer, William Humphrey

UAB Huntsville Research Day - All Presentations

2020 oral presentation

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Description Of Interprofessional, Community-Based Naloxone Nasal Spray Distribution And Education Events, Taylor Steuber, Larissa Pierce, Holly Clark, Shivani Malhotra Jan 2020

Description Of Interprofessional, Community-Based Naloxone Nasal Spray Distribution And Education Events, Taylor Steuber, Larissa Pierce, Holly Clark, Shivani Malhotra

UAB Huntsville Research Day - All Presentations

2020 research poster

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Direct Primary Care In Rural Communities, Dusty Trotman, David Bramm Jan 2020

Direct Primary Care In Rural Communities, Dusty Trotman, David Bramm

UAB Huntsville Research Day - All Presentations

2020 research poster

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Dalbavancin Is An Effective And Safe Outpatient Treatment Option For Pyogenic Discitis Caused By Methicillin-Resistant Staphylococcus Aureus (Mrsa), Syed Shabee Hassan, Hafiz Muhammad Fazeel, Ali Hassoun Jan 2020

Dalbavancin Is An Effective And Safe Outpatient Treatment Option For Pyogenic Discitis Caused By Methicillin-Resistant Staphylococcus Aureus (Mrsa), Syed Shabee Hassan, Hafiz Muhammad Fazeel, Ali Hassoun

UAB Huntsville Research Day - All Presentations

2020 clinical vignette poster

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Have You Ever Been Told You Have A Murmur?, Mariam Riad, Erin Britt, Roger D. Smalligan, John Fanning Jan 2020

Have You Ever Been Told You Have A Murmur?, Mariam Riad, Erin Britt, Roger D. Smalligan, John Fanning

UAB Huntsville Research Day - All Presentations

2020 clinical vignette poster

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The Yin And Yang Of Hepatitis C Infection (Hcv) & B-Cell Non-Hodgkin Lymphoma, Paul St Clair, Katherine E. Glosemeyer, Farrah Ibrahim, Rachel C. Kruspe Jan 2020

The Yin And Yang Of Hepatitis C Infection (Hcv) & B-Cell Non-Hodgkin Lymphoma, Paul St Clair, Katherine E. Glosemeyer, Farrah Ibrahim, Rachel C. Kruspe

UAB Huntsville Research Day - All Presentations

2020 clinical vignette poster

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Cytomegalovirus Induced Thrombocytopenia With No Platelets In An Immunocompetent Young Male, Sujatha Baddam, Jose Cavo, Kushdeep Chahal Jan 2020

Cytomegalovirus Induced Thrombocytopenia With No Platelets In An Immunocompetent Young Male, Sujatha Baddam, Jose Cavo, Kushdeep Chahal

UAB Huntsville Research Day - All Presentations

2020 clinical vignette poster

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Visceral Artery Aneurysm: An Unusual Cause Of Abdominal Pain, Maha Al-Baghdadi, Parekha Yedla Jan 2020

Visceral Artery Aneurysm: An Unusual Cause Of Abdominal Pain, Maha Al-Baghdadi, Parekha Yedla

UAB Huntsville Research Day - All Presentations

2020 clinical vignette poster

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Oritavancin In The Treatment Of Infective Endocarditis In Iv Drug Abusers, Maha Al-Baghdadi, Ali Hassoun Jan 2020

Oritavancin In The Treatment Of Infective Endocarditis In Iv Drug Abusers, Maha Al-Baghdadi, Ali Hassoun

UAB Huntsville Research Day - All Presentations

2020 clinical vignette poster

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