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Method Development Of Drug Court Samples, Kourtney Michelle Steen Jan 2022

Method Development Of Drug Court Samples, Kourtney Michelle Steen

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This project was done in collaboration with the Jefferson County Drug Court system. The Drug Court program is available in Jefferson County to youth and adults to help first time offenders with felony drug offenses. Individuals can have their cases dismissed once they complete the rehabilitation program. There are three phases to the Drug Court program with random drug screens conducted through a color-coded selection system. The phases are correlated to completing screens weekly, bi-weekly, or monthly. The program is completed once the individual has a clean drug test for 90 days. The overall objectives of this research project were …

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An Evaluation Of The In Vitro Antibacterial, Biocompatibility, And Mineralization Properties Of Six Calcium Silicate-Based Pulp Capping Materials, Taimy Cruz Hondares Jan 2022

An Evaluation Of The In Vitro Antibacterial, Biocompatibility, And Mineralization Properties Of Six Calcium Silicate-Based Pulp Capping Materials, Taimy Cruz Hondares

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Purpose: The purpose of this study was to evaluate the antibacterial activity, biocompatibility, and mineralization-inducing potential of calcium silicate-based pulp capping materials. Methods: Six contemporary calcium silicate-based pulp capping materials were compared in this study, including ProRoot MTA, MTA Angelus, Biodentine, EndoSequence, NeoMTA 2 and NeoPutty. The antibacterial effects of these materials against Streptococcus mutans UA159 and Enterococcus faecalis ATCC 29212 were determined by the agar-diffusion assay and the direct culture test. The biocompatibility and mineralization-inducing potential of these materials in preodontoblastic 17IIA11 cells were compared by the MTT assay and by evaluating alkaline phosphatase activity and calcium deposits, respectively. …

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Socioeconomic Status, Hbb, And Ttr Variants, And Cardiorenal Outcomes: The Regards Study, Onika E. Abrams Jan 2022

Socioeconomic Status, Hbb, And Ttr Variants, And Cardiorenal Outcomes: The Regards Study, Onika E. Abrams

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Blacks are disproportionately affected by heart failure (HF) and end-stage renal disease (ESRD). While poorer health outcomes in Blacks have been associated with social determinants of health, there are some biological differences worth noting, namely genetic risk variants for both TTR and HBB. These genetic risk variants are known to confer additional risk in the development of heart failure and end-stage renal disease, respectively. While we understand these genetic variants aren’t fully penetrant, and genetics and are not deterministic, we aimed to examine additional factors and mechanisms responsible for the increased risk in HF and ESRD in Blacks. Neighborhood socioeconomic …

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Optimal Antero-Posterior Position Of The Maxillary Central Incisors And Its Relationship To The Forehead In Adult Hispanic Females, Balraj Bains Jan 2022

Optimal Antero-Posterior Position Of The Maxillary Central Incisors And Its Relationship To The Forehead In Adult Hispanic Females, Balraj Bains

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Objective: The objective of this study is to investigate the relationship of forehead inclination to anteroposterior position (AP) of the maxillary central incisors in adult Hispanic females. Materials and Methods: 70 participants were recruited for this study and smiling profile photographs were taken. All images were deidentified and placed in standardized dimension of 7.5” by 6.5”, which were then added to a PowerPoint to be evaluated by a judging panel. 24 Adult Hispanic Females (AHF) made up the control group and were seen to have an optimal incisor AP position. 46 AHF were in the study group and were judged …

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Association Between Regional Covid-19 Vaccine Hesitancy And Reported Positive Covid-19 Cases In The Southern United States, Orielle Caudle Jan 2022

Association Between Regional Covid-19 Vaccine Hesitancy And Reported Positive Covid-19 Cases In The Southern United States, Orielle Caudle

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The use of vaccinations has been shown to be beneficial in pandemics in the past, and in some cases, it has led to elimination of a particular disease (i.e. polio). The COVID-19 vaccination can also serve the same purpose, however, vaccine hesitancy within specific regions of the country may prevent and/or dilute the effectiveness of the vaccine. Vaccine hesitancy can be defined as a delay in acceptance, or refusal despite the availability of vaccine services. Southern regions have consistently had the lower vaccination rates compared to its other regional counterparts, even as the pandemic progressed and death rates increased over …

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Evaluation Of Repair Strength Of Conventional, Milled, And Printed Resin Provisional Crown Materials With Different Surface Treatments And Repair Resins, Bright Jesuk Chang Jan 2022

Evaluation Of Repair Strength Of Conventional, Milled, And Printed Resin Provisional Crown Materials With Different Surface Treatments And Repair Resins, Bright Jesuk Chang

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Statement of Problem: Provisional (also known as interim or transitional) restorations are important in fixed prosthodontics to evaluate long-term esthetics, phonetics, and function while protecting the tooth preparation from bacterial infiltration and maintaining periodontal health. Recent advances in CAD/CAM technologies have allowed these restorations to be either milled or printed. However, there is a lack of literature regarding the repair and reline of these milled and/or printed restorations. Purpose: To evaluate the repair strength of conventional, milled, and printed resin provisional crown materials with different surface treatments and repair resins. Materials and Methods: This in vitro study examined the shear …

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Dear Former Phenom, Meredith Beretta Jan 2022

Dear Former Phenom, Meredith Beretta

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Dear Former Phenom is a collection of essays and poems covering my life as a female athlete in America, beginning when I was a small child and continuing to my retirement after my senior year as a collegiate student-athlete. As it stands, the collection is incomplete. This current version contains the core memories and the foundation of my discussion. This collection tells the story of my failure to reach my full potential as an athlete. It is the story of me constantly achieving higher and higher achievements, awards, accolades, and praise until I didn’t anymore. Until there was no one …

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The Roles Of Racial Discrimination And Sleep In Cognitive Functioning In Diverse Youth, Queenisha Crichlow Jan 2022

The Roles Of Racial Discrimination And Sleep In Cognitive Functioning In Diverse Youth, Queenisha Crichlow

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Cognitive functioning is an important aspect of human development that is closely related to youth academic outcomes (Caemmerer et al., 2018). Specifically, there is evidence that cognitive abilities such as memory, attention, and self-control are predictive of academic achievement in youth (Peng & Kievit, 2020). Current research suggests that chronic stress reduces cognitive functioning (Korten et al., 2014), but few studies have examined this relationship for race-related stress, specifically racial discrimination. Considering that racial discrimination is a common and reoccurring type of stress in the lives of minority youth (Hughes et al., 2016), it is possible that chronic exposure to …

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Smoking And Perceived Stress: Examining The Impact Of Racial Identity And Risk For Obstructive Sleep Apnea Through A Moderated Mediation Model, Sofia Mildrum Chana Jan 2022

Smoking And Perceived Stress: Examining The Impact Of Racial Identity And Risk For Obstructive Sleep Apnea Through A Moderated Mediation Model, Sofia Mildrum Chana

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Background: Cigarette smoking is known to have a negative effect on individuals’ sleep quality, and symptoms of insomnia. Smoking can particularly exacerbate sleep disorders such as obstructive sleep apnea (OSA) by increasing irritation and inflammation of the upper respiratory conducts. Previous research highlights the complex positive association between cigarette smoking and perceived stress. Sleep may be an important aspect intervening in the association between smoking and perceived stress, given that individuals who report high stress also report worse sleep quality and are at greater risk for OSA. However, limited research has examined the indirect association of cigarette smoking and perceived …

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Effects Of Different Types Of Augmented Feedback On Spatiotemporal Gait Performance And Intrinsic Motivation With Individuals Post Stroke, Saleh M. Alhirsan Jan 2022

Effects Of Different Types Of Augmented Feedback On Spatiotemporal Gait Performance And Intrinsic Motivation With Individuals Post Stroke, Saleh M. Alhirsan

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After a stroke, an individual can be left with physical and psychological deficits, including decreased walking speed, reduced step length, and reduced intrinsic motivation. These deficits affect their performance during rehabilitation sessions, limit daily activities such as walking and stepping, and restrict participation in social roles that involve mobility. Current clinical practice guidelines recommend providing augmented feedback using virtual reality (VR) to enhance walking outcomes after six months of stroke onset. This dissertation shows two novel VR applications designed, especially for individuals’ post-stroke, to induce their fast-walking speed and maximum step length performance, and intrinsic motivation. Three performance conditions were …

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Improving Continuity And Quality Assurance In Internet Of Things Infrastructure Using Blockchain, Hussain A. Alshehri Jan 2022

Improving Continuity And Quality Assurance In Internet Of Things Infrastructure Using Blockchain, Hussain A. Alshehri

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In this research I present a rigorous study on the service continuity and quality assurance using the Internet of Things (IoT). The research aims at identifying risks and improving the risk mitigation tools that are currently in use for improving the IoT performance, and for pushing forward the implementation of IoT in mission critical applications. This objective can be accomplished by identifying the impact of the strategic planning, quality assurance, performance assurance, and risk management on the IoT used in businesses. While the focus is mainly on the business continuity domain, the technical aspects of IoT solutions are also covered. …

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Prolonged Prone Positioning For Covid-19-Induced Acute Respiratory Distress Syndrome: A Randomized Pilot Study, David Brian Page Jan 2022

Prolonged Prone Positioning For Covid-19-Induced Acute Respiratory Distress Syndrome: A Randomized Pilot Study, David Brian Page

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ationale: Prone positioning is one of the few interventions shown in a robust, randomized, controlled clinical trial to reduce mortality in severe ARDS. Ideal duration of prone positioning is unknown. A 16-hour prone positioning period has been studied and is considered standard, although longer duration may be beneficial. Objectives: Determine if a prolonged prone positioning strategy for patients with COVID-19-induced ARDS is feasible and safe. Methods: We performed a pilot, randomized, parallel-arm feasibility study in patients with COVID-19-induced ARDS. Patients were randomized to either a prolonged 24-hour or a traditional 16-hour prone positioning strategy. Measurements & Main Results: 52 patients …

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The Potential Roles Of Broccoli Sprouts (Bsp) And Green Tea Polyphenols (Gtps) In Prevention Of Mammary Cancer, Itika Arora Jan 2022

The Potential Roles Of Broccoli Sprouts (Bsp) And Green Tea Polyphenols (Gtps) In Prevention Of Mammary Cancer, Itika Arora

All ETDs from UAB

Cancer is one of the leading causes of death in the United States. Based on the American Cancer Society statistics, in 2021 1,806,590 new cancer cases and 605,520 cancer deaths are projected to occur in the United States. Amongst all, breast cancer (BC) is one of the most prevalent cancers that occurs in women. Various lifestyle factors such as alcohol intake, smoking, an unhealthy diet and physical inactivity may result in increased rates of BC risks (cancer-transition) by inducing mutations in DNA. Numerous epidemiological studies indicate that a diet rich in green tea polyphenols (GTPs), and/or cruciferous vegetables such as …

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Invisible No More: Lgbtq History & Archiving Projects At Universities In The South, Maigen Sullivan Jan 2022

Invisible No More: Lgbtq History & Archiving Projects At Universities In The South, Maigen Sullivan

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LGBTQ history within the US South is rich and diverse though it has remained mostly absent from mainstream and academic narratives around LGBTQ history generally. In recent years, there has been a growing effort to location, preserve, research and make accessible to the community the history of the Queer and Trans South. Despite stereotypes of the South as a hyper-conservative, homophobic, and transphobic region, many public history and community archiving projects have begun on public universities across the South. This qualitative constructivist grounded theory research explored the ways in which LGBTQ public history and community archiving projects on public universities …

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Photothermal Desorption Of Volatile Organic Compounds From Buckypaper Sorbents, For Occupational Exposure Assessment, Jacob S. Shedd Jan 2022

Photothermal Desorption Of Volatile Organic Compounds From Buckypaper Sorbents, For Occupational Exposure Assessment, Jacob S. Shedd

All ETDs from UAB

Volatile organic compounds (VOCs) are a common source of occupational exposures. To prevent adverse health effects in employees, industrial hygienists must regularly conduct occupational air sampling to ensure exposures remain below regulatory limits. As such, the need for sensitive and reliable exposure assessment methodologies becomes apparent. Currently, diffusive sampling is popular and well-established exposure assessment method amongst professionals. However, its reliance on diffusion-driven mass uptake and chemical extraction, results in limited analytical sensitivity. In response to this, a pre-analytical technology, known as photothermal desorption (PTD), has been in development over the past decade. PTD uses pulses of high-energy light to …

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Characterization Of The Phenotype And Functional Properties Of Myeloid Subpopulations In Chronic Inflammatory Conditions, Krystle Leandra Ong Jan 2022

Characterization Of The Phenotype And Functional Properties Of Myeloid Subpopulations In Chronic Inflammatory Conditions, Krystle Leandra Ong

All ETDs from UAB

Myeloid cells represent a subset of leukocytes traditionally recognized as first responders to acute inflammatory stimuli. In recent years, there has been a growing appreciation of the role of myeloid cells as critical regulators of the immune system in disease pathogenesis and progression. Chronic inflammatory diseases including viral infections, autoimmune diseases, and malignancies are frequently associated with altered myelopoiesis characterized by a profound shift in the myeloid cell phenotype and function. The work presented in this dissertation provides an insight into dysregulated myelopoiesis and myeloid heterogeneity in multiple myeloma (MM), human immunodeficiency virus-1 (HIV-1), and coronavirus disease-19 (COVID-19). We identify …

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The Role Of Nitric Oxide And Cyclic Guanosine Monophosphate Signaling In Arteriovenous Fistula Maturation, Maheshika S. Somarathna Jan 2022

The Role Of Nitric Oxide And Cyclic Guanosine Monophosphate Signaling In Arteriovenous Fistula Maturation, Maheshika S. Somarathna

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Vascular access is the single most important component of the hemodialysis procedure and the arteriovenous fistula (AVF) is the most preferred type. However, 60% of AVFs created fail to mature successfully for dialysis use (AVF maturation failure). AVF maturation failure is primarily the result of 1) intimal hyperplasia formation (IH) and 2) poor vascular outward remodeling. Currently, a major unmet clinical need in the field is the lack of effective therapies to treat/prevent AVF maturation failure due to the poor understanding of molecular mechanisms. This proposal is designed to: 1) elucidate the pathologic significance of nitric oxide (NO) and cyclic …

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Life-Space Mobility In The Older Adult, Community-Dwelling Cancer Survivor In The Deep South: A Secondary Data Analysis, Richard A. Taylor Jan 2022

Life-Space Mobility In The Older Adult, Community-Dwelling Cancer Survivor In The Deep South: A Secondary Data Analysis, Richard A. Taylor

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By 2040, the U.S. is projected to have 26.1 million cancer survivors; 73% of these will be over 65 years old. Much is known about life-space mobility (LSM) in patients with non-cancer serious illnesses. Restricted LSM affects every aspect of an older adult’s life; their independence, autonomy, and quality of life (QOL). To date, there are no studies examining LSM in older cancer survivors. Therefore, we examined LSM, factors that affect LSM, and the relationship between LSM and QOL in older cancer survivors using existing data from the University of Alabama at Birmingham (UAB) Study of Aging (SOA) (NIA AG15062). …

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The Roles Of Repressive And Activating Epigenetic Factors In Vertebrates Neural And Neural Crest Development, Saeid Mohammad Parast Jan 2022

The Roles Of Repressive And Activating Epigenetic Factors In Vertebrates Neural And Neural Crest Development, Saeid Mohammad Parast

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The vertebrate nervous system comes from specific regions of the ectoderm that comprises of the neural plate and the neural crest. Although genetic mechanisms governing vertebrate neural development have been investigated in depth, there is a knowledge gap regarding the roles of epigenetic mechanisms in this process. As epigenetic modulators, the COMPASS (also known as SET1/MLL complex) and HP1 proteins are responsible for regulating chromatin accessibility to transcription factors. COMPASS is responsible for deposition of activating histone H3K4 methylation marks at promoters and enhancers and thus creates open chromatin domains. The critical structural and regulatory subunits of COMPASS, Dpy30 and …

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Acute Superior Vena Cava (Svc) Syndrome, An Unusual Occurrence, Muhammad Mohsin Zafar, Christopher Terrell, Imamuddin F. Mohammed, Alan Baggett Jan 2022

Acute Superior Vena Cava (Svc) Syndrome, An Unusual Occurrence, Muhammad Mohsin Zafar, Christopher Terrell, Imamuddin F. Mohammed, Alan Baggett

UAB Huntsville Research Day - All Presentations

2022 clinical vignette poster

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Predictors And Disparities Associated With Pain (Pandda-P) Study: A Comparison Of Pediatric Rheumatology Patients, Kathryn Ann Thompson Jan 2022

Predictors And Disparities Associated With Pain (Pandda-P) Study: A Comparison Of Pediatric Rheumatology Patients, Kathryn Ann Thompson

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Background: Chronic pain is a prominent feature of many pediatric rheumatic conditions. However, the diagnosis, experience, and treatment of musculoskeletal pain varies by condition. Therefore, the overall aim of the present study is to elucidate group differences and examine biopsychosocial correlates of pain in children with juvenile idiopathic arthritis (JIA), juvenile primary fibromyalgia syndrome (JPFS), non-specific chronic pain (NSCP), and pain-free controls.Methods: We recruited 117 (66% female, 73% White) school-aged children from Children’s of Alabama Rheumatology and Allergy Clinics and the community. Participants self-reported their pain, physical function, sleep, pain-related stigma, and somatic symptoms and underwent experimental pain tasks. Caregivers …

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Effect Of Saliva Contamination On Crown Retention Strengths Of Resin And Rmgi Cements, Bushra Nizami Jan 2022

Effect Of Saliva Contamination On Crown Retention Strengths Of Resin And Rmgi Cements, Bushra Nizami

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Background: The most common contaminant in the oral cavity is saliva. Many studies have shown that contamination with saliva negatively affects the strength of the resin-dentin bond. A literature review by Nair et al reported that 64.6% of studies on the topic show a detrimental effect of salivary contamination on adhesive materials. No published studies were found that thoroughly studied the effects of saliva contamination on RMGIs and resin cements with regards to crown retention rates. Objective: To study the effect of salivary contamination on crown retention strengths of RMGI and resin cements at various stages of bonding and in …

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The Effect Of Maxillary Sinus Anatomical Variations, Surgical Considerations, And Patient Factors On Volumetric Changes Following Lateral Wall Sinus Floor Elevation Technique For Up To 8 Years, Mengyi Shi Jan 2022

The Effect Of Maxillary Sinus Anatomical Variations, Surgical Considerations, And Patient Factors On Volumetric Changes Following Lateral Wall Sinus Floor Elevation Technique For Up To 8 Years, Mengyi Shi

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jectives: The aim of this retrospective study is to assess the long-term dimensional stability, or shrinkage, of the lateral window sinus grafts using cone beam computed tomography scans (CBCT) and radiographic software. Material and Methods: All patients from UAB Periodontal Graduate Clinic with available records of sinus augmentation via the lateral window approach with delayed implant placement between 2014 and 2019 were screened for having two follow up CBCT scans of diagnostic quality. The first scan must be completed within 6-9 months of lateral window sinus floor elevation (LWSFE) and prior to implant placement. The second CBCT must be taken …

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A Comparison Of Growth Factor Release Between Platelet Rich Fibrin And Recombinant Human Platelet Derived Growth Factor Bb (Rhpdgf-Bb) And Beta-Tricalcium Phosphate: An In Vitro Analysis, Maggie Ann Misch Jan 2022

A Comparison Of Growth Factor Release Between Platelet Rich Fibrin And Recombinant Human Platelet Derived Growth Factor Bb (Rhpdgf-Bb) And Beta-Tricalcium Phosphate: An In Vitro Analysis, Maggie Ann Misch

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Patients presenting with significant alveolar bone loss can pose challenges for the clinician. Traditional bone augmentation techniques may be inadequate in achieving necessary gains to restore missing teeth with dental implants. The adjunctive use of growth factors may accelerate the healing process and enhance tissue regeneration. GEM21S is a product that includes a recombinant growth factor approved by the Federal Drug Administration for oral surgery. It is delivered as a two-component system: 1) recombinant human platelet-derived growth factor-BB (rhPDGF-BB) and 2) betatricalcium phosphate (β-TCP).[1] The research on GEM 21S for ridge augmentation is mostly limited to case studies.[2- 4] Biologically, …

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Effect Of Etch Time On Sbs Of Machinable Lithium Disilicate Glass Ceramics Using Variolink Esthetic Lc, Mayur Chandrakant Nayee Jan 2022

Effect Of Etch Time On Sbs Of Machinable Lithium Disilicate Glass Ceramics Using Variolink Esthetic Lc, Mayur Chandrakant Nayee

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The purpose of this study is to measure the shear bond strength between dental cement and four different machinable, lithium disilicate glass ceramics, under varied etch time with hydrofluoric acid. Ten specimens each of 4 different machinable blocks of lithium disilicate were mounted in cylinders of pink acrylic resin. Each specimen was subjected to etching with hydrofluoric acid, rinsing with water from an air / water nozzle, drying with compressed air, application of a silane primer (Monobond Plus, Ivoclar Vivadent) for at least 60 seconds, then mounted in an Ultradent jig and Variolink Esthetic LC (Ivoclar Vivadent) cement extruded through …

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Regional Variations In The Incidence Of Brain Glioma In Adults In Alabama, Mina Lobbous Jan 2022

Regional Variations In The Incidence Of Brain Glioma In Adults In Alabama, Mina Lobbous

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Purpose: Gliomas are the most common primary brain tumor in adults in the US with an annual age-adjusted incidence rate of 4.67 to 5.73 per 100,000 persons. Exposure to ioniz-ing radiation is the only established risk factor for non-hereditary glioma risk. There are several sources of carcinogenic contaminants in northeast Alabama and western Georgia with the Coosa River serving as the region’s primary water source. In this study, we aimed to examine the incidence rate of glioma in northeast Alabama compared to the rest of the state as well as the association of possible environmental exposure on disease risk and …

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Measuement Of Translucency, Biaxial Flexural Strength, And Radiopacity Of Different Lithium Disilicate Materials, Preshtha Mangla Jan 2022

Measuement Of Translucency, Biaxial Flexural Strength, And Radiopacity Of Different Lithium Disilicate Materials, Preshtha Mangla

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Objective: To measure translucency parameter, biaxial flexural strength, radiopacity and microstructure of various lithium disilicate materials used for dental restorations. Materials and Methods: CAD/CAM lithium disilicate glass-ceramic blocks: IPS e.max CAD (Ivoclar Vivadent), CerecTessera (Dentsply Sirona), and Amber Mill (Hassbio America) were used (shade A2, HT, and MT). Blocks of each material were milled (PrograMill PM7, Ivoclar Vivadent) into cylinders (diameter = 14 mm) and cut using circular sectioning saw (IsoMET 1000 Precision Saw, Buehler) into disc-shaped specimens (thickness = 1.00 ± 0.05 mm) (n=5/group). They were hand polished to 1200 grit with SiC paper under water lubrication. The translucency …

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A Systematic Study Of Data Security Issues In Smart Home Iot Devices, Hilal Nur Issi Jan 2022

A Systematic Study Of Data Security Issues In Smart Home Iot Devices, Hilal Nur Issi

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The best description of IoT comes from the International Telecommunication Union (ITU), which defines it as "a global infrastructure for the information society, enabling advanced services by interconnecting things based on existing and evolving interoperable information and communication technologies" (ITU, 2013). Different things, equipment, and household are employed in daily living in our world. The advantages that smart technology provides have piqued the curiosity of academics and practitioners alike. Home appliances have received a lot of attention, since smart technology has been extensively explored and put into practice. A great deal of research has gone into automating the house, making …

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The Association Between Paraquat Exposure And Parkinson's Disease Mortality: A County-Level Ecological Study In The United States, Alexander Kozuch Jan 2022

The Association Between Paraquat Exposure And Parkinson's Disease Mortality: A County-Level Ecological Study In The United States, Alexander Kozuch

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Objectives: The current study reports the results of an ecological study regarding the association between PQ exposure and Parkinson’s disease mortality in the United States. Methods: The outcome of interest for this study was mortality due to Parkinson’s disease, obtained from CDC Wonder. The exposure of interest was PQ exposure at the county level which was obtained from the United States Geological Survey (USGS). Statistical analysis was done using the mortality data, grouped into ten-year age groups, and focused on data from 2015-2019 to account for the lag time between initial Paraquat exposure and Parkinson’s Disease mortality. A Negative Binomial …

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The Relationship Between Psychological Profiles And Longitudinal Pain Trajectories In People With Chronic Knee Pain, Daniel Alexander Kusko Jan 2022

The Relationship Between Psychological Profiles And Longitudinal Pain Trajectories In People With Chronic Knee Pain, Daniel Alexander Kusko

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Considerable evidence demonstrates that radiographic findings (e.g., osteophytes) are only modestly associated with the severity of knee pain, suggesting that other biopsychosocial factors likely influence symptom severity. Multiple psychological factors have been linked to worse health outcomes in people with chronic knee pain; however, it remains unclear whether psychological profiles might help explain variability in knee pain severity. The primary goal of this study was to identify unique psychological differences among people with and without chronic knee pain, and then examine whether psychological profiles longitudinally predicted knee pain trajectories over two years. Individuals with (n = 175) and without (n …

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