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Articles 10831 - 10860 of 14457
Full-Text Articles in Entire DC Network
Inquiro 5 (Complete Issue), Inquiro Staff
Inquiro 5 (Complete Issue), Inquiro Staff
Inquiro (undergraduate research journal)
No abstract provided.
Nasa: Is It The End Or Only The Beginning?, Amlya Ahmed
Nasa: Is It The End Or Only The Beginning?, Amlya Ahmed
Inquiro (undergraduate research journal)
p. 4
An Evaluation Of The Spoons Program On An Acute Care For Elders (Ace) Unit, Michael Chang
An Evaluation Of The Spoons Program On An Acute Care For Elders (Ace) Unit, Michael Chang
Inquiro (undergraduate research journal)
pp. 14-16
Interview With Stephen Barnes, Phd, Miranda Collier
Interview With Stephen Barnes, Phd, Miranda Collier
Inquiro (undergraduate research journal)
pp. 23-24
Effects Of Sulforaphane And Cisplatin Treatments On A2780-Cp20 Ovarian Cancer Cell Line, Sadhvi Batra, Shweta Patel, Syed Meeran, Trygve O. Tollesfbol
Effects Of Sulforaphane And Cisplatin Treatments On A2780-Cp20 Ovarian Cancer Cell Line, Sadhvi Batra, Shweta Patel, Syed Meeran, Trygve O. Tollesfbol
Inquiro (undergraduate research journal)
pp. 25-28
A Proposed Model Of Apoptosis Of Pancreatic Insulin-Secreting Beta-Cells, Winnie Tsai, Nikhita Jain, Karen J. Goodwin, Xiaoyong Lei, Sasanka Ramanadham
A Proposed Model Of Apoptosis Of Pancreatic Insulin-Secreting Beta-Cells, Winnie Tsai, Nikhita Jain, Karen J. Goodwin, Xiaoyong Lei, Sasanka Ramanadham
Inquiro (undergraduate research journal)
pp. 29-33
Inquiro 5 (End Matter), Inquiro Staff
Inquiro 5 (End Matter), Inquiro Staff
Inquiro (undergraduate research journal)
pp. 69-72
The Effects Of Diet On Crystallin Protein Levels In The Zebrafish Lens, Miranda Collier, Kyle Floyd, Landon Wilson, Daniel Smith, Om Srivastava, Stephen Barnes
The Effects Of Diet On Crystallin Protein Levels In The Zebrafish Lens, Miranda Collier, Kyle Floyd, Landon Wilson, Daniel Smith, Om Srivastava, Stephen Barnes
Inquiro (undergraduate research journal)
pp. 60-67
Post-Transcriptional Control Of Type I Interferon Genes By Ksrp In The Innate Immune Response Against Viral Infection, Wei-Jye Lin
Post-Transcriptional Control Of Type I Interferon Genes By Ksrp In The Innate Immune Response Against Viral Infection, Wei-Jye Lin
All ETDs from UAB
Several strategies are used in eukaryotic cells in order to determine the gene expression level, including the transcriptional and post-transcriptional mechanisms. One of the post-transcriptional mechanisms is the regulation of mRNA stability, which varies considerably from one mRNA species to another. Previous studies have shown that inherently unstable mRNAs encoding cytokines and proto-oncogenes contain the AU-rich elements (AREs) in the 3' untranslated regions (UTRs). Their decay requires decay-promoting RNA-binding proteins that recognize the AREs and recruit mRNA decay machineries to facilitate the rapid decay of targeting mRNA. KH-type splicing regulatory protein (KSRP) was previously identified as an ARE decay promoting …
The Effect Of Changes In Tort Laws On Cesarean Section Rates In The United States, Allison Jean Taylor
The Effect Of Changes In Tort Laws On Cesarean Section Rates In The United States, Allison Jean Taylor
All ETDs from UAB
"Defensive medicine", medical practice decisions based on fear of malpractice litigation and where risks may outweigh health and cost benefits, is a proposed contributor to increasing cesarean rates in the U.S. Some studies suggest that changes in laws governing medical malpractice actions may decrease the cesarean rate by relieving pressures driving defensive medicine. This study examined whether, in states that have adopted certain tort reform measures, the probability of having a cesarean delivery is lower following implementation of the reform measures. A database of state legislation and court decisions and National Center for Health Statistics natality data files (1991-2004) were …
Statistical Methods In The Analysis Of Copy Number Variation Data, Nathan Wineinger
Statistical Methods In The Analysis Of Copy Number Variation Data, Nathan Wineinger
All ETDs from UAB
Copy number variation is a significant form of genetic variation that has been shown to influence many traits. However, current methods used to estimate copy number variation are imprecise and prone to errors. This property is demonstrated in a study examining copy number variation in African Americans recruited into the Hypertensive Genetic Epidemiology Network study, and who were genotyped on the Affymetrix 6.0 array. The effect this has on downstream association analyses is explored, an alternative methods are proposed. Finally, a method is proposed that uses linkage disequilibrium between copy number variants and single nucleotide polymorphisms to improve the accuracy …
An Examination Of Statistical Methods For Longitudinal Mediation Modeling, John Paul Bentley
An Examination Of Statistical Methods For Longitudinal Mediation Modeling, John Paul Bentley
All ETDs from UAB
The use of mediation modeling is quite prevalent in a number of disciplines to answer questions about how or why one variable exerts its influence on another variable. Although mediation can be assessed in the context of several types of study designs, the use of cross-sectional data and a single-mediator model tend to be the most commonly reported features in empirical tests of mediation. There are several limitations associated with assessing mediation with cross-sectional data, perhaps the most significant is that mediated effect estimates are biased in the case of true longitudinal mediation. For this and several other reasons, there …
Mechanisms And Consequences Of Thy-1 Shedding, John Edwin Bradley
Mechanisms And Consequences Of Thy-1 Shedding, John Edwin Bradley
All ETDs from UAB
Idiopathic Pulmonary Fibrosis (IPF) is characterized by chronic fibrosis in the lung interstitium of unknown etiology, and causes death within 2 to 4 years after diagnosis. There are no clinical interventions save for lung transplantation that give any survival benefit. Aberrant collagen deposition and aggregates of proliferating fibroblasts and myofibroblasts called fibroblastic foci (FF) are the classic features of IPF. Therefore, the cell type most often implicated as pathogenic in IPF is the fibroblast, especially its differentiated phenotype, the myofibroblast. Fibroblasts are a remarkably heterogeneous cell type. Expression of the cell surface glycoprotein Thy-1 (Thymocyte differentiation antigen 1) delineates a …
The Effect Of An Inclusive Trauma System On Homicide Risk In An Urban Population, Russell Griffin
The Effect Of An Inclusive Trauma System On Homicide Risk In An Urban Population, Russell Griffin
All ETDs from UAB
Homicide is a leading cause of mortality in the United States, with approximately 18,000 homicides occurring annually. Most prevention efforts for homicide are aimed at primary (e.g., culling aggressive behaviors among youth) or secondary (e.g., preventing repeat violence) efforts. To date, there has been limited research on tertiary prevention efforts of homicide (i.e., preventing homicide by preventing deaths from assault-related injuries). With the advent of trauma systems (TS), which allow for rapid emergency medical response for injured individuals, it is possible that these systems may be an ef-fective effort of tertiary prevention of homicides. Using data from the Jefferson County …
The Effects Of Weight Loss And Exercise On Relative Bmd In Premenopausal Women, Kara Cook Hamilton
The Effects Of Weight Loss And Exercise On Relative Bmd In Premenopausal Women, Kara Cook Hamilton
All ETDs from UAB
Heavier individuals have higher bone mineral density (BMD) than individuals of lower body weight, but it is unclear whether BMD changes in proportion to body weight during weight loss. This study compared BMD relative to body weight following a six month weight loss program and a one-year weight maintenance phase in premenopausal women and determined whether African American (AA) and European-American (EA) women's BMD respond similarly during weight loss. Premenopausal women (n=115, 34±5 yrs.) were evaluated in an overweight state (BMI between 27 and 30 kg/m2), following an 800 kcal/day diet/exercise program designed to reduce BMI <25 kg/m2, and one-year following weight loss. Results indicated that BMD relative to body weight increased after weight loss, but decreased during the one-year weight maintenance phase. However, all one-year follow up BMD measurements were increased (all significant except Ward's triangle and L1) when compared to baseline measurements. These sites included the hip neck (mean Z-score difference of 0 .088, P=0.014), the greater trochanter (mean difference of 0.089, P=0.003), total hip (mean Z-score difference of 0.099, P=0.001), L2 (mean Z-score difference of 0 .126, P<0.013), L3 (mean Z-score difference of 0.136, P=0.014), and L4 (mean Z-score difference of 0.186, P=0.005). AAs had significantly higher BMD at all sites compared to EAs, but no time by race interactions were evident during weight loss (except in L3). These results indicate that it is safe and beneficial for overweight premenopausal women to lose weight since it improves BMD relative to body weight, while also combating obesity, heart disease, high blood pressure, and type II diabetes.
The Relationship Between Sunlight And Cerebrovascular Health, Shia T. Kent
The Relationship Between Sunlight And Cerebrovascular Health, Shia T. Kent
All ETDs from UAB
Sunlight radiation may be related to stroke risk through increased vitamin D production. The latter has been associated with a number of conditions including stroke, cognitive function and cardiovascular disease. We performed three sets of analyses to determine whether higher levels of sunlight radiation were associated with lower rates of stroke incidence, all-cause mortality, and cognitive decline. We explored these relationships using the REasons for Geographic And Racial Differences in Stroke (REGARDS) study, a national longitudinal cohort of 30,239 participants. We merged the participants' residential histories with a ground and satellite-derived NASA dataset to characterize 15-year average sunlight radiation and …
Sox2/Parylated Parp1 Complexes Regulate Pluripotency, Yi-Shin Lai
Sox2/Parylated Parp1 Complexes Regulate Pluripotency, Yi-Shin Lai
All ETDs from UAB
Embryonic stem cells (ESCs) were first derived from the inner cell mass (ICM) of blastocyst-stage embryos. ESCs are distinguished from other cell types by their pluripotency and unlimited self-replication. ESCs are able to differentiate into multiple cell types that represent all three primary germ layers (ectoderm, mesoderm and endoderm) and can form an entire adult organism. Under defined conditions, ESCs are self-renewable and have an extended life-span without compromising pluripotency. The plasticity of ESCs provides opportunities for regenerative medicine. The recent production of induced pluripotent stem cells (iPSC) offers an ideal "personalized" substitute for ESCs. Overexpression of four transcription factors, …
A Study Of The Relationships Among Maternal Caregiver Family Management Behaviors, Childhood Asthma Morbidity, And Asthma Control, Linda M. Gibson
A Study Of The Relationships Among Maternal Caregiver Family Management Behaviors, Childhood Asthma Morbidity, And Asthma Control, Linda M. Gibson
All ETDs from UAB
A STUDY OF THE RELATIONSHIPS AMONG MATERNAL CAREGIVER FAMILY MANAGEMENT BEHAVIORS, CHILDHOOD ASTHMA MORBIDITY, AND ASTHMA CONTROL ABSTRACT LINDA GIBSON NURSING Childhood asthma, the most common chronic childhood condition, is associated with high rates of asthma morbidity (emergency department visits, hospitalizations, and school days missed due to asthma). Inadequate asthma control accounts for $1.9 billion annual health expenditures. Numerous studies have identified the relationship of the family caregiver's perception regarding asthma management and the child's asthma outcomes; though few have examined family caregiver asthma management behaviors. Knafl and colleagues (2003) defined family management behaviors as accommodations that family members use …
Neighborhood Context As A Predictor Of Nursing Home Placement Among Older Adults, David Russell Buys
Neighborhood Context As A Predictor Of Nursing Home Placement Among Older Adults, David Russell Buys
All ETDs from UAB
Persons who are aging face an increased risk of adverse health events and decreased levels of personal competencies, potentially inhibiting their ability to age in place. Sometimes, nursing home placement (NHP) may be imperative, especially if persons experience environmental docility-- an incongruence of their physical capacity with their environment. This study links the neighborhood disadvantage literature with Lawton's environmental press and environmental docility theories to examine how the environment interacts with individual level variables to impact likelihood of NHP. Findings suggest that there is not a direct link between living in a disadvantaged context and likelihood of NHP, but that …
Biology And Conservation Of The Diamondback Terrapin, Malaclemys Terrapin Pileata, In Alabama, Andy Coleman
Biology And Conservation Of The Diamondback Terrapin, Malaclemys Terrapin Pileata, In Alabama, Andy Coleman
All ETDs from UAB
The diamondback terrapin is the only obligate estuarine turtle in North America and is considered an integral member of the salt marsh ecosystem. Unfortunately, many populations throughout the terrapin's range have experienced size declines due to past overexploitation and have been unable to rebound due to current threats including crab trap mortality, habitat degradation, nest predation, and road mortality. The current study was the first comprehensive study examining various population and conservation parameters of Mississippi diamondback terrapins in Alabama. Through various field survey methods conducted in numerous salt marshes along the Gulf Coast of Alabama, it was concluded that Cedar …
Understanding Molecular Mechanisms Of Breast Cancer Metastasis Using Genetically-Engineered Mice, Leah M. Cook
Understanding Molecular Mechanisms Of Breast Cancer Metastasis Using Genetically-Engineered Mice, Leah M. Cook
All ETDs from UAB
Morbidity and mortality of breast cancer patients are drastically increased when primary tumor cells metastasize to distant organ sites. Effective treatment of metastatic disease has been limited; therefore, an increased molecular understanding to identify biomarkers and therapeutic targets is needed. Breast cancer metastasis suppressor 1 (BRMS1) suppresses development of metastases when expressed in a variety of cancer types, including metastatic mammary carcinoma. Little is known of Brms1 function throughout the initiation and progression of mammary carcinoma. Thus Brms1 transgenic mice (derived on C57BL/6 background) were generated by utilizing MMTV promoter expression (for mammary-selective overexpression) or the beta-actin promoter (for ubiquitous …
The Effects Of Runx2 Deficiency In Cartilaginous And Mineralized Craniofacial Element, David Summerford
The Effects Of Runx2 Deficiency In Cartilaginous And Mineralized Craniofacial Element, David Summerford
All ETDs from UAB
The development of the orofacial structure in mammals is a highly ordered process that is coordinated activity of epithelial and mesenchymal cells. Chondrocytes and osteoblasts work in close association for development of many cartilaginous skeletal structures and cartilaginous orofacial structures. Two major orofacial structures are the palate and the temporomandibular joint (TMJ). The transcription factor, Runx2, is obligatory for differentiation of mesenchymal cells into chondrocytes and osteoblasts. However, specific contributions of chondrocyte in cartilaginous and mineralized structures of the craniofacial skeleton are not known. Thus, the objective of this study was to discover the regulatory role of Runx2 in chondrocyte …
Individual, Socio-Cultural And Structural Factors Associated With Cervical Cancer Screening And Treatment In Tanzania, Renicha Tomeka Mccree-Hale
Individual, Socio-Cultural And Structural Factors Associated With Cervical Cancer Screening And Treatment In Tanzania, Renicha Tomeka Mccree-Hale
All ETDs from UAB
Most African countries including Tanzania have limited cervical cancer screening and treatment programs. Only about 5% of women have ever been screened for cervical cancer. A constellation of individual and structural factors contributes to the challenge of cervical cancer screening and treatment in countries that bear significant burdens of disease. Yet, little is known about country specific factors that may constrain or facilitate scale up of health services. This dissertation is an attempt to identify and understand the country specific individual and structural barriers along with facilitators to cervical cancer screening and treatment in Tanzania. Individual, institutional and structural level …
Limited Transplantation Of Antigen-Expressing Hematopoietic Stem Cells Induces Long-Lasting Cytotoxic T Cell Responses And Effect Of Altered Suppressive Myeloid Population On Hiv-Disease Progression, Warren L. Denning
All ETDs from UAB
While each type of cancer and chronic viral infection has its own specific pathology, they share two common mechanisms of immune evasion. The first mechanism is the exhaustion or deletion of antigen-specific T cells. The second mechanism is the formation of an immunosuppressive environment responsible for the block of T cell function. Elicitation of antigen-specific T cells be accomplished by immunotherapy in place of conventional treatments such as HAART and chemotherapy. In addition, immunotherapy can alleviate the side-effects associated with long-term use of conventional therapies while reducing the total cost. The results presented here provide an alternative to conventional methods …
Vulcan Historical Review 15 (Front Matter), Vulcan Historical Review Staff
Vulcan Historical Review 15 (Front Matter), Vulcan Historical Review Staff
Vulcan Historical Review
No abstract provided.
Twentieth Century Alabama Agriculture: Sharecropping, Agribusinesses , And Direct Marketing, Josh Hodge
Twentieth Century Alabama Agriculture: Sharecropping, Agribusinesses , And Direct Marketing, Josh Hodge
Vulcan Historical Review
pp. 120-140
Segregation And Sterilization: Reassessing Alabama's Eugenic Past, James M. Hurst
Segregation And Sterilization: Reassessing Alabama's Eugenic Past, James M. Hurst
Vulcan Historical Review
pp. 51-69
Florence Nightingale: Anticipating The Germ Theory Of Disease, Samuel 'Yana' Davis
Florence Nightingale: Anticipating The Germ Theory Of Disease, Samuel 'Yana' Davis
Vulcan Historical Review
pp. 30-50
The Great Influenza Of 1918 And The Alabama Debacle, Maya J. Orr
The Great Influenza Of 1918 And The Alabama Debacle, Maya J. Orr
Vulcan Historical Review
pp. 70-96
Berry G. Jackson, Alias Berry Clyatt: Murder, Witness, And Murderer, Jessica Parker Newman
Berry G. Jackson, Alias Berry Clyatt: Murder, Witness, And Murderer, Jessica Parker Newman
Vulcan Historical Review
pp. 186-213