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Metal Complexes Of Sulfamethazine/Benzoin-Based Schiff Base Ligand: Synthesis,Characterization, Dft Calculations, And Antimicrobial Activities, Kerem Buran
Turkish Journal of Biology
Background/aim: The global rise in bacterial resistance poses a significant challenge, exacerbated by the overuse of antibacterial agents. Schiff base-metal complexes have gained attention for their potential antimicrobial properties, attributed to their unique three-dimensional structures and modes of action, such as cell wall inhibition and membrane disruption. The aim of this study was to synthesize and characterize a novel Schiff base (L) derived from sulfamethazine and benzoin, and to develop metal complexes of it with Cu2+, Co2+, Ni2+, and Cd2+. This research sought to evaluate the antibacterial and antifungal activities of the synthesized Schiff base and its metal complexes to …
Luminescence Dating And Its Application To Anthropogenic Sedimentary Sequences:Tepecik-Çiftlik Prehistoric Settlement, Eren Şahi̇ner, Mehmet Korhan Erturaç
Luminescence Dating And Its Application To Anthropogenic Sedimentary Sequences:Tepecik-Çiftlik Prehistoric Settlement, Eren Şahi̇ner, Mehmet Korhan Erturaç
Turkish Journal of Earth Sciences
Luminescence dating is a fundamental technique in the field of earth sciences research, offering a reliable method fordetermining the age of sediments and artifacts. Applications of luminescence dating in archaeology include the dating of ancienthabitation sites, burial mounds, and artifacts such as pottery. This provides a chronological framework for understanding humanactivities and environmental changes over millennia. The capacity of luminescence dating to ascertain the age of events spanning a fewdecades to several hundred thousand years renders it an indispensable instrument for the construction of timelines and interpretationof the past. This study presents a concise overview of the various stages of …
Evaluation Of Physical And Chemical Condition Of A Group Of Waterloggedarchaeological Woods From The Yenikapı 16 Shipwreck, Sedef Hetto, Namik Kiliç, Asli Gökçe Kiliç
Evaluation Of Physical And Chemical Condition Of A Group Of Waterloggedarchaeological Woods From The Yenikapı 16 Shipwreck, Sedef Hetto, Namik Kiliç, Asli Gökçe Kiliç
Turkish Journal of Earth Sciences
This study examined the physical and chemical condition of waterlogged archaeological wood (WAW) samples from the Yenikapı 16 shipwreck of plane (Platanus L.), elm (Ulmus L.), pine (Pinus L.), and fir (Abies L.), representing species with different wood properties. The maximum water content (MWC) and basic density (BD) values of 74 WAW samples from the shipwreck were calculated, and 7 of 74 samples were selected for analysis using scanning electron microscopy (SEM), X-ray fluorescence (XRF), and Fourier transform infrared spectroscopy (FTIR). The availability of samples, appropriate size, the species of the wood, and the wood’s degradation were all considered. The …
Geochemical Discriminants For The Provenance Characterization Of Ceramics, Kiymet Deni̇z Yağcioğlu, Yusuf Kağan Kadioğlu
Geochemical Discriminants For The Provenance Characterization Of Ceramics, Kiymet Deni̇z Yağcioğlu, Yusuf Kağan Kadioğlu
Turkish Journal of Earth Sciences
Cultural heritage can be effectively protected and restored by accurately identifying archaeometric materials used inhistorical sites, such as rocks, ceramics, bricks, mortar, and plaster, and determining their origins. This interdisciplinary study employsmineralogical, petrographic, and isotopic properties together with geochemical analyses to ascertain the origins of these materials. Thisstudy focuses on the provenance characterization of ceramics as possible source rocks of ceramic raw material using new geochemicaldiscrimination diagrams. Detailed geochemical analyses of manufactured ceramics from various rock types from different locationswere conducted and new geochemical discrimination diagrams were created to determine the origins of the ceramics. The geochemicaldata of ceramics that …
Environmental And Cultural Impacts Of The 8.2 Ka Event In Yenikapı (İstanbul/Türkiye), Ayşi̇n Konak, M. Namik Yalçin
Environmental And Cultural Impacts Of The 8.2 Ka Event In Yenikapı (İstanbul/Türkiye), Ayşi̇n Konak, M. Namik Yalçin
Turkish Journal of Earth Sciences
The Neolithic lifestyle, which began in the 12th millennium BP with the emergence of villages in the core region extendingfrom Iran to central and southeastern Anatolia and Syria, began to spread to neighboring geographies, such as the Marmara region,in the 9th millennium BP. During the 8.2 ka event that occurred between 8300 and 7900 BP, cold and dry conditions prevailed in thenorthern hemisphere. During the winter months, the humidity decreased and cooling of about 6 ± 2 °C was observed. In order totest whether the 8.2 ka event was also effective in the İstanbul region, a set of inorganic geochemical …
Characterization Of Thin Marble Slabs Cut With Roman Water-Powered Stone Saw Millsfrom Western Asia Minor, Hakan Elçi̇, Ramazan Hacimustafaoğlu, Serdar Aybek
Characterization Of Thin Marble Slabs Cut With Roman Water-Powered Stone Saw Millsfrom Western Asia Minor, Hakan Elçi̇, Ramazan Hacimustafaoğlu, Serdar Aybek
Turkish Journal of Earth Sciences
This study examined the mineralogical, petrographic, technological, and material properties of thinly cut marble slabs usedin the flooring and cladding of the frigidarium section of a bath constructed in the 2nd century AD in Metropolis, a city that connectedtwo significant centers in Western Asia Minor-Ephesus and Smyrna-during the Roman period. The study also explains the possibletechniques and methods by which these marble slabs could have been cut so thinly. The thickness of the marble slabs used was closelyrelated to their material properties. Bluish grey, with calcite veins with low flexural strength, containing medium to coarse crystallinecalcite veins, and white marbles …
Minero-Petrographic, Geochemical, And Multiisotopic Characterization Of The Ancientbanded Travertine Quarries Of The Lycus Valley (Denizli, Türkiye), Tamer Koralay, Nergi̇s İmre
Minero-Petrographic, Geochemical, And Multiisotopic Characterization Of The Ancientbanded Travertine Quarries Of The Lycus Valley (Denizli, Türkiye), Tamer Koralay, Nergi̇s İmre
Turkish Journal of Earth Sciences
The Lycus Valley in Western Anatolia has been the site of numerous civilizations since ancient times due to historical, geopolitical, and climatological characteristics. Banded travertine is a ubiquitous architectural stone observed in ancient settlements in the Lycus Valley. Banded travertines referred to as “Alabastro Fiorito,” “Alabastro Listato,” and “Alabastro Rossa” in archaeological bibliographies have been extracted from the ancient quarries of Çukurbağ, Hierapolis, Develi-Akköy, Gölemezli, and Tripolis in the Lycus Valley and are characterized by white, yellow, brown, red, and red-burgundy colored bands with thicknesses ranging from a few millimeters to centimeters. The banded travertines have similar mineral compositions and …
Classification Of Asia Minor Marbles Based On Crystal Size For Archaeometric Assignment, Ramazan Hacimustafaoğlu, Hakan Elçi̇
Classification Of Asia Minor Marbles Based On Crystal Size For Archaeometric Assignment, Ramazan Hacimustafaoğlu, Hakan Elçi̇
Turkish Journal of Earth Sciences
This study was carried out to determine the range of crystal sizes of Asia Minor marbles and to classify the marbles accordingto crystal size. Asia Minor marbles have been used as building stones since ancient times. The literature already includes studies on theircrystal sizes; however, different studies performed on marbles of the same locality have reported different crystal size classes, which hascaused complexity. To eliminate this complexity, this study used multidirectional petrographic analyses on the eight known Asia Minormarbles. Thin sections were photographed under a polarizing microscope, and the crystal sizes of the samples were measured usingcomputerized image analysis. An …
Petrography, Electron Paramagnetic Resonance, Geochemistry, And Sr-C-O Isotope Datafor Provenance Studies Of The Ancient Marmor Iassense In Kıyıkışlacık(Muğla Region), Türkiye, Namik Aysal, Emre Erdem, Nurullah Hani̇lçi̇, Tali̇p Güngör, Si̇nan Öngen, İsak Yilmaz, Fulya Uzun, Davut Laçi̇n, İpek Deni̇z Yildirim
Petrography, Electron Paramagnetic Resonance, Geochemistry, And Sr-C-O Isotope Datafor Provenance Studies Of The Ancient Marmor Iassense In Kıyıkışlacık(Muğla Region), Türkiye, Namik Aysal, Emre Erdem, Nurullah Hani̇lçi̇, Tali̇p Güngör, Si̇nan Öngen, İsak Yilmaz, Fulya Uzun, Davut Laçi̇n, İpek Deni̇z Yildirim
Turkish Journal of Earth Sciences
The Marmor Iassense (Iasos marble, Marmor Carium) banded marbles, produced from the Kızılağaç Formation near thevillage of Kıyıkışlacık, have been favorite marbles from ancient times to the present day with their colors and patterns. During theRoman and Byzantine periods, they were preferred as decorative stones for many important buildings in İstanbul, such as the HagiaSophia, Chora Monastery (Kariye Mosque), and Church of the Holy Apostles, as well as San Vitale in Ravenna and other buildingsthroughout the Mediterranean region. They were used in wall coverings, flooring, columns, and mosaics. These marbles contain redand gray-white alternating folded layers of different thicknesses. They …
Characterization Of Stone Materials From The Roman Caracalla Bath In Ancyra, Zeynep Tanriverdi̇, Ali̇ Akin Akyol, Yusuf Kağan Kadioğlu
Characterization Of Stone Materials From The Roman Caracalla Bath In Ancyra, Zeynep Tanriverdi̇, Ali̇ Akin Akyol, Yusuf Kağan Kadioğlu
Turkish Journal of Earth Sciences
The Roman Caracalla Bath was built during the reign of Roman Emperor Caracalla (circa AD 200). Today it exists only inthe form of wall remnants at the foundation level and functions as an open-air museum. It is located on a mound approximately 2.5-mhigh along Ulus’s Çankırı Street in Ankara. This research paper aims to identify the characterization and implications for provenance ofthe stone materials used in the construction of the bath by using mineralogical, petrographic, and geochemical definitions. The resultsobtained from the stone materials also provide guidance for restoration and reinforcement of the bath. In this study, the 13 stone …
Digital Documentation Of A Byzantine Rock-Carved Structure In Konya:Kiriakon Monastery, Sille, Hasan Bi̇lgehan Maki̇neci̇, İlker Mete Mi̇mi̇roğlu, Esra Yaldiz, Hakan Karabörk
Digital Documentation Of A Byzantine Rock-Carved Structure In Konya:Kiriakon Monastery, Sille, Hasan Bi̇lgehan Maki̇neci̇, İlker Mete Mi̇mi̇roğlu, Esra Yaldiz, Hakan Karabörk
Turkish Journal of Earth Sciences
Digital documentation methods enable the acquisition of viable data to preserve cultural heritage and its accurate transferto future generations. Unmanned aerial vehicle (UAV) and terrestrial laser scanning (TLS) equipment are technical tools that haveessential functions in the three-dimensional (3D) modeling of structures of historical importance. In the geographic referencing andvisualization of historical structures with their surroundings, UAVs are often used, and for the visualization of the interior spaces ofstructures as a whole, TLS is popular. The Kiriakon Monastery, a rock-carved, cross-in-square, four-supports simple provincial typeof church, and several different structures around it within the borders of Sille in Konya Province …
Multianalytical Characterization Of Byzantine Wall Paintings By Sem-Edx,Μ-Xrd, Raman And Ftir Techniques, Onur Şi̇mşek, Fati̇h Özbaş, Ersi̇n Kaygisiz, Gözem Yaşayan, Gülce Öğrüç Ildiz
Multianalytical Characterization Of Byzantine Wall Paintings By Sem-Edx,Μ-Xrd, Raman And Ftir Techniques, Onur Şi̇mşek, Fati̇h Özbaş, Ersi̇n Kaygisiz, Gözem Yaşayan, Gülce Öğrüç Ildiz
Turkish Journal of Earth Sciences
In this study, various analytical methods were employed to examine the mineral based natural pigments in the frescoes of themedieval (9th century) Byzantine church, known today as the Atik Mustafa Pasha Mosque. The techniques include μ-X-ray diffraction(μ-XRD), Raman and Fourier transform infrared (FTIR) spectroscopies, and scanning electron microscopy coupled with energydispersive X-ray spectroscopy (SEM–EDX). The SEM-EDX technique enabled the identification of the chemical element compositionin the studied pieces, while Raman and FTIR spectroscopies, as well as XRD, allowed the identification of mineral phases and mineralbased natural pigments in the paints of the frescoes. Fragments of various colors (red, black, yellow, …
Rocks Used In Polished Stone Axe Production In Eastern Thrace (Türkiye) During Theneolithic Period: A Geochemical, Petrographic, And Geoarchaeological Approach, Ti̇mur Ustaömer, Zeynep Özbey, M. Namik Yalçin, Mehmet Celal Özdoğan, Eylem Özdoğan, İsmai̇l Ozan Çilgin, Abdüssamed Güven
Rocks Used In Polished Stone Axe Production In Eastern Thrace (Türkiye) During Theneolithic Period: A Geochemical, Petrographic, And Geoarchaeological Approach, Ti̇mur Ustaömer, Zeynep Özbey, M. Namik Yalçin, Mehmet Celal Özdoğan, Eylem Özdoğan, İsmai̇l Ozan Çilgin, Abdüssamed Güven
Turkish Journal of Earth Sciences
Twenty-nine Neolithic polished stone axes from various archaeological sites in Eastern Thrace and İstanbul were analyzedin this study using petrographic and geochemical methods to identify their lithologies and locate their source rocks. We found thatvariable rock types, including diabase, siltstone, lava, granite, and serpentinite, were used to produce these stone tools in workshops.The same techniques were applied to samples of potential source rocks from a large area in NW Türkiye to determine the locations ofthe source rocks used to produce the stone axes. Diabase dykes of Şarköy ophiolite were identified as the source rock for the diabasepolished stone axes, the …
Antifungal Prophylaxis In High-Risk Patients With Hematologic Malignancy:A Comparison Of Practice With Guidelines In Türkiye, Özlem Güzel Tunçcan, Seçki̇n Çağirgan, Hakan Özdoğu, Si̇nem Ci̇vri̇z Bozdağ, Fi̇li̇z Vural, Mustafa Pehli̇van, Hüseyi̇n Saffet Beköz, Yasemi̇n Esen, Tuba Koç, Petek Gi̇li̇k, Esi̇n Şenol
Antifungal Prophylaxis In High-Risk Patients With Hematologic Malignancy:A Comparison Of Practice With Guidelines In Türkiye, Özlem Güzel Tunçcan, Seçki̇n Çağirgan, Hakan Özdoğu, Si̇nem Ci̇vri̇z Bozdağ, Fi̇li̇z Vural, Mustafa Pehli̇van, Hüseyi̇n Saffet Beköz, Yasemi̇n Esen, Tuba Koç, Petek Gi̇li̇k, Esi̇n Şenol
Turkish Journal of Medical Sciences
Background/aim: Primary antifungal prophylaxis (AFP) is recommended by guidelines as the gold standard for patients with hematologic malignancies. This study aimed to investigate the level of knowledge and translation of guideline recommendations into real-life setting among physicians in Türkiye.Materials and methods: In this prospective, observational study, the physicians’ knowledge of ΑFP guideline recommendations in patients with acute myeloid leukaemia (AML) or myelodysplastic syndrome (MDS) undergoing first remission-induction (Group I), and graft-versus-host-disease (GvHD) after allogeneic stem cell transplant (Group II), was compared with clinical practice via 11-item multiple-choice questionnaire evaluating the timing and patients in whom AFP was initiated, with AFP …
Synthetic Osteobiologics In Spine Surgery: A Review, Aydin Si̇nan Apaydin, Eli Johnson, Prince Antwi, Brett Rocos, Michael M. Haglund, Christopher Shaffrey, Peter Passias, Muhammad Adb-El-Barr, Khoi Than
Synthetic Osteobiologics In Spine Surgery: A Review, Aydin Si̇nan Apaydin, Eli Johnson, Prince Antwi, Brett Rocos, Michael M. Haglund, Christopher Shaffrey, Peter Passias, Muhammad Adb-El-Barr, Khoi Than
Turkish Journal of Medical Sciences
Background/aimOsteobiologics are increasingly used in orthopedics and spine surgery to facilitate bone healing and prevent non-union. Synthetic osteobiologics are artificial materials crafted in laboratories that aim to replicate the natural composition and functionality of bone. Notable examples, such as calcium phosphate and calcium sulfate, are engineered to mirror the mineral aspect of bone. They mimic human bone functionality, exhibiting osteoconductive, osteoinductive, and osteogenic properties. These characteristics promote cell attachment, migration, recruitment, and differentiation. Consequently, synthetic osteobiologics (osteoconductive grafts) have been introduced in bone fracture repair. The main strength of synthetic osteobiologics in spine surgery lies in improving fusion rates and …
New Index For Distinguishing Between Critical Illness Myopathy And Neuromyopathy: Cmap Amplitude/Duration Index, Handan Uzunçakmak Uyanik, Fatma Gökçem Yildiz, Çağri Mesut Temuçi̇n
New Index For Distinguishing Between Critical Illness Myopathy And Neuromyopathy: Cmap Amplitude/Duration Index, Handan Uzunçakmak Uyanik, Fatma Gökçem Yildiz, Çağri Mesut Temuçi̇n
Turkish Journal of Medical Sciences
Background/Aim: Critical illness-associated weakness (CIAW) is a common neuromuscular syndrome that may manifest as critical illness myopathy (CIM), critical illness polyneuropathy (CIP), or an overlap syndrome known as critical illness polyneuromyopathy (CIPM). Distinguishing between these subtypes can be challenging due to technical issues, patient-related factors such as insufficient cooperation with needle electromyography (EMG) and edema, and the need for sophisticated, time-consuming electrophysiological methods and invasive procedures such as biopsy. This study aims to contribute to the electrophysiological distinction between CIM and CIPM. Materials and methods: A new index was calculated based on distal compound muscle action potential (CMAP) amplitude and …
Evaluation Of Nonmotor Symptoms In Myasthenia Gravis Patients, Aysel Tekeşi̇n, Çağla Şi̇şman, Ufuk Emre Toprak, Alena Sar, Burcu Akalin, Goncagül Koşargeli̇r, Meli̇h Tütüncü, Enes Yi̇ği̇t
Evaluation Of Nonmotor Symptoms In Myasthenia Gravis Patients, Aysel Tekeşi̇n, Çağla Şi̇şman, Ufuk Emre Toprak, Alena Sar, Burcu Akalin, Goncagül Koşargeli̇r, Meli̇h Tütüncü, Enes Yi̇ği̇t
Turkish Journal of Medical Sciences
Background/aim: Myasthenia gravis (MG) is chronic autoimmune disorder characterized primarily by muscle weakness and fatigue, due to autoantibodies targeting acetylcholine receptor at neuromuscular junction. In this study, we aimed to evaluate non-motor symptoms in myasthenia gravis patients and compare them with disease duration, severity and clinical features.Materials and methods: This prospective study was conducted with thirty-five myasthenia gravis patients and thirty-five healthy volunteers. Total of 35 patients, 17 women and 18 men with mean age of 52.9±13.6 years constituted patient group. Control group consisted of total of 35 participants, 23 women and 12 men with mean age of 46.9±12.2 years. …
Inflammatory Changes In The Prepuce And Clinical Findings According To The Stages Of Phimosis, Gül Doğan, Di̇lek Yilmaz, Hülya İpek, Mehmet Meti̇n, Hande Afşarlar, Çağatay Evri̇m Afşarlar
Inflammatory Changes In The Prepuce And Clinical Findings According To The Stages Of Phimosis, Gül Doğan, Di̇lek Yilmaz, Hülya İpek, Mehmet Meti̇n, Hande Afşarlar, Çağatay Evri̇m Afşarlar
Turkish Journal of Medical Sciences
Background/aim: Circumcision refers to the surgical removal of all or part of the prepuce. Circumcision is commonly performed on males in childhood to prevent urinary tract infections and for religious reasons. This study was designed to investigate the inflammatory processes in the prepuce according to the degree of phimosis in patients who underwent circumcision.Materials and methods: We conducted a prospective study on 173 male children under the age of 18 who underwent circumcision between June and September 2024. A comprehensive physical examination of the genitourinary system was performed. Foreskin retraction was assessed and recorded using the Kikiros grading score, and …
Relationship Between Hand Osteoarthritis Severity And Serum Resistin Levels In Women With Metabolic Syndrome: A Case-Control Study, Eki̇n Başak Doğanci, Berna İmge Aydoğan, Ni̇lgün Başkal, Safi̇ye Tuncer
Relationship Between Hand Osteoarthritis Severity And Serum Resistin Levels In Women With Metabolic Syndrome: A Case-Control Study, Eki̇n Başak Doğanci, Berna İmge Aydoğan, Ni̇lgün Başkal, Safi̇ye Tuncer
Turkish Journal of Medical Sciences
Background/aimWe aimed to determine the relationship between clinical and radiological severity of hand osteoarthritis and serum resistin levels in women diagnosed with metabolic syndrome.Materials and methodsThe study was designed as a case-control study. A total of 87 women aged 50-65 years were evaluated; 29 patients diagnosed with metabolic syndrome and hand osteoarthritis (MetS (+), hand OA (+); Group 1), 29 patients without metabolic syndrome but with hand osteoarthritis (MetS (-), hand OA (+); Group 2) and 29 healthy controls (MetS (-), hand OA (-); Group 3). The diagnostic criteria of American College of Rheumatology (ACR) for hand osteoarthritis and National …
Impact Of Ivermectin On Nerve Regeneration Following Sciatic Injury In Mice: The Consequences Of Dietary High Fructose, Ezgi̇ Deni̇z Arikan, Barişcan Çi̇men, Ayşe Ece Gezen Yilmaz, Eli̇f Akaydin, Berkay Alpay, Deni̇z Eki̇n Erbaş, Erblina Nikshiqi, Sevda Müftüoğlu, Yildirim Sara
Impact Of Ivermectin On Nerve Regeneration Following Sciatic Injury In Mice: The Consequences Of Dietary High Fructose, Ezgi̇ Deni̇z Arikan, Barişcan Çi̇men, Ayşe Ece Gezen Yilmaz, Eli̇f Akaydin, Berkay Alpay, Deni̇z Eki̇n Erbaş, Erblina Nikshiqi, Sevda Müftüoğlu, Yildirim Sara
Turkish Journal of Medical Sciences
Background/aimPeripheral nerve injuries (PNI) are debilitating disorders affecting predominantly the younger generation, often leading to significant disabilities. Current treatment strategies are inadequate in addressing the complex nature of these injuries. Peripheral nerve healing and functional recovery are crucial components of both pathophysiology and therapeutic approach. High fructose corn syrup (HFCS) is a frequently used sweetener in several beverages and foods. And it is associated with several metabolic disturbances including insulin resistance and may impair nerve healing. This study investigates the therapeutic role of ivermectin on nerve regeneration following sciatic nerve injury and evaluates motor and sensorial functions together with histopathological …
Association Of Certain Biochemical Parameters Related To Bone Cycle With Genotype In Mps Iii-B Patients, Seda Gökkurt, İrem Peker Eyüboğlu, Banu Nur Güzel, Ercan Mihçi, Ayşe Özer, Mustafa Akki̇pri̇k
Association Of Certain Biochemical Parameters Related To Bone Cycle With Genotype In Mps Iii-B Patients, Seda Gökkurt, İrem Peker Eyüboğlu, Banu Nur Güzel, Ercan Mihçi, Ayşe Özer, Mustafa Akki̇pri̇k
Turkish Journal of Medical Sciences
Background/aim: The aim of this study is to investigate the genotype-phenotype correlation in Sanfilippo type B patients in terms of bone formation/resorption parameters, and to determine the release/inhibition of biomarkers accompanying osteoporosis.Materials and Methods: Plasma levels of Osteoprotegerin, Matrix metalloproteinases (MMP2, MMP9), TIMP-1, TIMP-2, BALP, Cathepsin K, and TRACP-5b were examined by ELISA method in MPS IIIB patients. At the same time, mutations in the NAGLU gene causing this disease were detected by whole exome sequencing, and their correlation with biochemical parameters was investigated.Results: Based on the enzyme analysis results, MMP-9, TIMP1, TIMP-2, and MMP-2 were significantly high, while Cathepsin-K …
Paradigm Shift In Obesity Treatment: An Extensive Review Of Current Pipeline Agents, Ecesu Çeti̇n, Brian Pedersen, Mehmet Furkan Burak
Paradigm Shift In Obesity Treatment: An Extensive Review Of Current Pipeline Agents, Ecesu Çeti̇n, Brian Pedersen, Mehmet Furkan Burak
Turkish Journal of Medical Sciences
Obesity is a multifaceted disease that poses a significant public health challenge. Recent discoveries in understanding the biological pathways that regulate satiety and metabolism have led to a shift in the treatment paradigm for obesity. Thus, the gap between pharmacological and surgical interventions has diminished. The latest approved anti-obesity medications are achieving weight loss comparable to surgery. These GLP-1 analog-based therapies not only cause substantial weight loss but also improve obesity-associated comorbidities. However, there are still unmet needs in obesity care, and treatment options with alternative pathways are necessary. Whether achieved through lifestyle changes or medication, weight loss often leads …
A Comparison Study Of Sensory Processing In Older Adults With And Without Dementia, Medi̇ne Nur Özata Değerli̇, Di̇dem Karaduman, Burcu Balam Doğu, Onur Altuntaş
A Comparison Study Of Sensory Processing In Older Adults With And Without Dementia, Medi̇ne Nur Özata Değerli̇, Di̇dem Karaduman, Burcu Balam Doğu, Onur Altuntaş
Turkish Journal of Medical Sciences
Background/aim: Sensory processing is affected by aging, and dementia may lead to changes in sensory processing. This study aimed to examine the differences in sensory processing and sensory modulation between older adults with and without dementia.Materials and methods: This study was designed as a comparative study of community-dwelling older adults aged 65 years and older with and without dementia. Participants and their caregivers were recruited at the occupational therapy clinic of a public hospital. They completed a sociodemographic information form and the Adolescent/Adult Sensory Profile to assess sensory processing and sensory modulation.Results: The study included 120 older adults (60 with …
Novel Nonmagnetic Abutment Designs For Facial Prostheses: An Experimental Study, İrem Sozen Yani̇k, Ufuk Adali̇, Jamila Yassine, Fransizka Schmidt, Wolfgang Hannak, Bahadir Ersu
Novel Nonmagnetic Abutment Designs For Facial Prostheses: An Experimental Study, İrem Sozen Yani̇k, Ufuk Adali̇, Jamila Yassine, Fransizka Schmidt, Wolfgang Hannak, Bahadir Ersu
Turkish Journal of Medical Sciences
Background/aim: This in vitro study aimed to evaluate and compare the retentive forces of novel nonmagnetic abutment designs developed as an alternative to conventional magnetic abutments for facial prostheses.Materials and methods: A plexiglass model was constructed and two extraoral implants were placed in these blocks in a parallel position. Nonmagnetic abutments made of titanium were fabricated and screwed onto the implants. The nonmagnetic systems represent a novel design and include two different abutment designs (Type 1 and Type 2) with silicone attachments. Retentive force values for three abutment types: Conventional Magnetic System (CMS), Nonmagnetic abutment Type 1 System (NMS1), and …
A New Approach In The Treatment Of Ultrasound-Guided Synovial Hypertrophy, Emel Güler, Alper Doğanci
A New Approach In The Treatment Of Ultrasound-Guided Synovial Hypertrophy, Emel Güler, Alper Doğanci
Turkish Journal of Medical Sciences
Background/aimKnee osteoarthritis (OA) causes pain, limited movement, and negatively impacts daily life in older adults. Hypertrophy and changes in the synovial tissue significantly contribute to the pain. While intra-articular injections are common in OA treatment, specific therapies for hypertrophic tissue are rarely mentioned. This study aims to evaluate the long-term outcomes of local anesthetic and steroid injections in the knee's intra-articular space and hypertrophic synovial tissue.Materials and methodsOur retrospective study included patients with grade 3-4 kne OA diagnosed with ultrasound-guided suprapatellar effusion and synovial hypertrophy. Pain was assessed using the Numerical Rating Pain Scale (NRS), and functional capacity was evaluated …
Relationship Between Menstrual Cycle And Cognitive Functions In Women With Primary Dysmenorrhea, Ufuk Atlihan, Meltem Durakli Ulukök, Onur Yavuz
Relationship Between Menstrual Cycle And Cognitive Functions In Women With Primary Dysmenorrhea, Ufuk Atlihan, Meltem Durakli Ulukök, Onur Yavuz
Turkish Journal of Medical Sciences
Background/aim: To evaluate the relationship between the change in pain intensity over days in the menstrual-cycle and cognitive functions in females having primary dysmenorrhea.Materials and Methods: One hundred thirty-four females with primary dysmenorrhea who were admitted to our hospital from January 2021 to November 2023 were assessed. Of these participants, 46 individuals who subjectively stated that their cognitive functions were affected, for whom neurology consultation was requested, and for whom patient data were available, were included in the study.Results: Significant decrease was seen in phonemic fluency and semantic fluency in patients who were evaluated on the 3rd day of menstrual …
Efficiency Of Cervical Cerclage And Pessary In Addition To Vaginal Progesterone To Prevent Preterm Birth In Twin Pregnancies: A Case-Control Study From A Tertiary Center, Göksun İpek, Atakan Tanaçan, Ilim Demet, Zahi̇d Ağaoğlu, Ezgi̇ Başaran, Özgür Kara, Di̇lek Şahi̇n
Efficiency Of Cervical Cerclage And Pessary In Addition To Vaginal Progesterone To Prevent Preterm Birth In Twin Pregnancies: A Case-Control Study From A Tertiary Center, Göksun İpek, Atakan Tanaçan, Ilim Demet, Zahi̇d Ağaoğlu, Ezgi̇ Başaran, Özgür Kara, Di̇lek Şahi̇n
Turkish Journal of Medical Sciences
Background/aim: To evaluate the efficiency of cervical cerclage and pessary in addition to vaginal progesterone to prevent preterm birth in twin pregnanciesMaterials and methods: The presented retrospective case-control study was conducted on 46 twin pregnancies with cervical insufficiency and delivered at the xxx Hospital, January 2022-2024. Patients were grouped as the cervical cerclage in addition to vaginal progesterone (n=10), cervical pessary in addition to vaginal progesterone (n=11), and only vaginal progesterone (n=25). Patients’ data were obtained from the hospital database. Obstetrical parameters (gravidity, parity, abortion, artificial reproductive technologies, second-trimester abortion) and ultrasound parameters (cervical length, intra-amniotic sludge) were recorded. Gestational …
The Abdominal Compliance Index And Postoperative Pain After Laparoscopic Gynecologic Surgery: A Preliminary Observational Cohort Study, Ebru Akgün Şarer, Mustafa Tahtaci, Umut Cahi̇t Ersoy, Mehtap Honca
The Abdominal Compliance Index And Postoperative Pain After Laparoscopic Gynecologic Surgery: A Preliminary Observational Cohort Study, Ebru Akgün Şarer, Mustafa Tahtaci, Umut Cahi̇t Ersoy, Mehtap Honca
Turkish Journal of Medical Sciences
Background/aimLaparoscopic surgery in gynecology has advantages of reduced scarring, less postoperative pain, faster recovery and lower risk of complications. Despite these adavantages, shoulder pain still remains a major concern affecting upto 90% of patients undergoing gynecologic laparoscopic surgery. The use of Abdominal compliance index (ACI) may offer the benefits of gaining work space for safer surgery and may prevent the drawbacks of applying higher insuflation pressures.We investigated the relation of shoulder pain and abdominal pain and analgesic use with the recently advised ACI which is a surrogate index of abdominal expansion in patients undergoing gynecologic laparoscopic surgery.Materials and methodsThirty one …
Characteristics Of The Home Environment In Children With Developmental Concerns And Delays: Insights From A Cross-Sectional Study In Türkiye, Emel Ömerci̇oğlu, Ebru Ci̇han Çam, Ömer Nazim Gülçek, Eli̇f N. Özmert
Characteristics Of The Home Environment In Children With Developmental Concerns And Delays: Insights From A Cross-Sectional Study In Türkiye, Emel Ömerci̇oğlu, Ebru Ci̇han Çam, Ömer Nazim Gülçek, Eli̇f N. Özmert
Turkish Journal of Medical Sciences
Background/aim: A stimulating home environment in early childhood plays a crucial role in fostering child development. This study aimed to evaluate the home environment of children who were referred due to developmental delays or concerns and had not received any intervention at the child or family level.Materials and methods: The study comprised of 50 atypically developing preschool children monitored at the Developmental Pediatrics Department of *** and 70 typically developing preschool children from the General Pediatrics Department at ***. Physicians and experienced child development professionals employed the Ages and Stages Questionnaire (ASQ) to perform developmental assessments on each child. The …