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Lipopolysaccharide-Induced Acute Systemic Inflammation Is Associated With Depression-Like Behavior And Increased Hippocampal Epha4 Expression ​, Senem Esi̇n Yavaş, Özkan Yavaş, Ayşe Akbaş, Seda Işiklar, Semi̇ha Ersoy

Turkish Journal of Medical Sciences

Background/aim: Depression is a prevalent neuropsychiatric disorder with a complex etiology and a higher burden in women. The inflammation hypothesis, initially proposed based on parallels between depression and sickness behavior, has gained increasing support from accumulating evidence. EphA4, a regulator of synaptic plasticity, is highly expressed in the hippocampus and functions as a negative modulator of neuroplasticity.

Materials and methods: Hippocampal EphA4 expression was investigated in female Wistar rats subjected to lipopolysaccharide-induced acute systemic inflammation. Acute systemic inflammation was induced by intraperitoneal administration of lipopolysaccharide (5 mg/ kg). Depression-like behaviors were assessed using the open-field test and tail-suspension test, while …

Effects Of Topical Glycerin And Hydrogen Peroxide On Auditory Brainstem Response Thresholds In A Rat Model Of Tympanic Membrane Perforation ​, Özlem Akkoca, Emi̇ne Aydin, Şule Demi̇rci̇, Ridvan Hali̇t Pamuk, Emi̇ne Ceren Ersöz Ünlü, Harun Çoban, Yüce İslamoğlu

Turkish Journal of Medical Sciences

Background/aim: Cerumenolytic agents containing glycerin and hydrogen peroxide are widely used in clinical practice and are generally considered safe; however, their potential effects on hearing function in cases of tympanic membrane (TM) perforation have not been adequately investigated. This experimental study evaluated the potential ototoxic effects of glycerin and hydrogen peroxide in rats with TM perforations using auditory brainstem response (ABR) testing.

Materials and methods: Twenty healthy male Wistar albino rats with bilaterally induced near-total TM perforations were divided into four groups (n = 4–6 animals/group) and received topical saline, amikacin, glycerin, or hydrogen peroxide applications twice daily for 10 …

Psychological Distress Among Dental Students: A Comparative Study Of Preclinical And Clinical Stages ​, Ömer Faruk Sari, Eli̇f Albayrak, Muhammed Hi̇lmi̇ Büyükçavuş

Turkish Journal of Medical Sciences

Background/aim: Understanding the degree of psychological stress experienced by dental students, together with the contributing factors, is important for reducing the adverse effects of stress and improving student well-being. Accordingly, the present study examined psychological distress levels among dental students and compared psychological distress across different academic years.

Materials and methods: This cross-sectional study included all undergraduate students enrolled in a single 5-year dental faculty in Türkiye during the 2024–2025 academic year. The Kessler Psychological Distress Scale (K10) survey was administered to the students and 399 dentistry students filled out the survey completely.

Results: Statistically significant differences in K10 scores …

Comments On “Pregnancy Outcomes In Systemic Sclerosis Before And After Diagnosis: A Retrospective Nationwide Cohort Study” ​, Muhammad Faisal Shabbir, Muksh Maheshwari, Chand Raj, Maria Baloch

Turkish Journal of Medical Sciences

No abstract provided.

Multicentre Real-World Outcomes Of Reference Bevacizumab And Two Biosimilars In Treatment-Naïve Neovascular Age-Related Macular Degeneration ​, Eyüpcan Şensoy, Mehmet Çitirik, Burhan Başkan, Hasan Öncül, Abdullah Beyoğlu

Turkish Journal of Medical Sciences

Background/aim: Bevacizumab biosimilars are increasingly used as alternatives to reference bevacizumab in ophthalmic practice, but comparative real-world evidence in treatment-naïve neovascular age-related macular degeneration (nAMD) remains limited. In this study, the short-term anatomical, functional, and documented safety outcomes associated with bevacizumab, bevacizumab-bvzr (Zirabev), and bevacizumab-awwb (Mvasi) were evaluated in treatment-naïve patients with nAMD in a multicentre real-world setting.

Materials and methods: This multicentre retrospective cohort included 250 treatment-naïve eyes with nAMD from 16 centres in Türkiye that completed a 3-month loading regimen with the same bevacizumab agent. Central macular thickness (CMT) was the prespecified primary longitudinal outcome; best-corrected visual acuity …

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Turkish Journal of Veterinary & Animal Sciences

No abstract provided.

Evaluation Of Apoptosis In Peripheral Blood And Milk Immune Cells During Lactation In Dairy Cows With Subclinical Mastitis, Mykola Mykolayovich Zhelavskyi

Turkish Journal of Veterinary & Animal Sciences

The lactation cycle is considered one of the most physiologically demanding periods in dairy cows and is accompanied by substantial immunological remodeling. In the present study, spontaneous apoptosis of lymphocytes, monocytes, and neutrophils was evaluated in clinically healthy Ukrainian Black and White dairy cows (n = 28, aged 3–5 years) during different stages of the lactation cycle: colostrum period (3–5 days), mid‑lactation (90–150 days), drying‑off (5–7 days), and dry period (12–20 days). A further group of 28 cows with subclinical mastitis confirmed by the California Mastitis Test was also included in the study. Peripheral blood and milk samples were collected …

Combined Effects Of Postdistillation Residue Blends From Medicinal Plants On In Vitro Ruminal Microorganisms, Enzymes, Nitrogen And Energy Efficiency, And Antioxidant Status, Mojtaba Akbari Shooshood, Javad Rezaei, Mahdi Ayyari, Yousef Rouzbehan

Turkish Journal of Veterinary & Animal Sciences

In this study, the combined effects of postdistillation residue blends, including pomace, wastewater, and their mixture, derived from rosemary (RO), fennel (FE), spearmint (SP), and rose (ROS), on in vitro microbial populations, enzymatic activities, fermentation, and antioxidant status were evaluated using the gas production technique. The three phytobiotic blends were MP (mixed pomace of RO, FE, SP, and ROS; 1:1:1:1 ratio), MW (mixed wastewater of RO, FE, SP, and ROS; 1:1:1:1 ratio), and MPW (mixed pomace–wastewater of MP and MW; 1:1 ratio). Each blend was used at 2% and 3% of diet dry matter (DM). The experimental diets were as …

Changes In Mohair Cortisol Concentration And Fiber Growth During Gestation In Angora Goats, Beyzanur Aköz, Erkan Pehli̇van

Turkish Journal of Veterinary & Animal Sciences

The hypothalamic–pituitary–adrenal (HPA) axis plays a central role in regulating long-term stress responses. Keratin-based matrices represent a noninvasive approach for assessing long-term HPA axis activity in farm animals. The present study investigates gestational changes in mohair cortisol concentration and mohair fiber length in Angora goats under routine farm conditions. Clinically healthy does (n = 29; 14 aged 1.5 years and 15 aged 2.5 years) were monitored during the breeding season, and pregnancy was confirmed in 16 does. Mohair samples were collected monthly, fiber length was measured, and cortisol concentrations were quantified using an ELISA. Mohair cortisol concentrations were not significantly …

Ethylcyanoacrylate Adhesive And Microperforated Polyethylene Tape For The Cutaneous Closure Of Bitches Following Unilateral Total Mastectomy, Leonardo Martins Leal, Fábio Rodrigo Castro Bastos, Joseneia Boeing, Gabriel Aguiar Pavilak, Isaac Romani, Tais Harumi De Castro Sasahara, Paola Castro Moraes

Turkish Journal of Veterinary & Animal Sciences

The use of ethylcyanoacrylate (Super Bonder®) adhesive and microperforated polyethylene tape (Transpore) for the cutaneous closure of extensive wounds following unilateral mastectomy was evaluated, and the healing process was clinically assessed. Included in the study were 15 bitches diagnosed with mammary neoplasia, aged 4–14 years and weighing 3–33 kg. All bitches underwent a 30–60 cm craniocaudal cutaneous incision through the skin in the ventral thoracoabdominal region. Following excision of the tumor and the entire mammary chain, the adjacent tissues were approximated with polyglecaprone 25 sutures. Skin-edge coaptation was achieved through the application of adhesive to half of each wound, while …

Investigation Of Feed Values With In Vitro Technique And Chemical Properties, Particle Size Of Total Mixed Rations Prepared In Commercial Dairy Farms, Özlem Karcioğlu, Betül Zehra Sariçi̇çek

Turkish Journal of Veterinary & Animal Sciences

This study was conducted to investigate the chemical and physical properties and feed values of total mixed rations used on dairy cattle farms in Ankara Province. Included in the study were three farms from each of the five districts of Ankara Province (atotal of 15 commercial dairy farms). Total mixed ration (TMR) samples were collected weekly from each farm over a 3-month period in 2025. The chemical composition (crude protein, crude fat, crude fiber, acid detergent fiber (ADF), neutral detergent fiber (NDF), and acid detergent lignin (ADL)), in vitro digestibility parameters (in vitro gas production (IVGP), methane production (MP), organic …

Optimizing Marination Methodology, Holding Temperature, And Holding Time To Upgrade The Physicochemical And Sensorial Attributes Of Japanese Quail (Coturnix Japonica) Breast Fillets, Naveen Uduwawithana, Ruvini Mutucumarana

Turkish Journal of Veterinary & Animal Sciences

The aim was to optimize the effect of meat marination method (unmarinated, tumbling, injection, and immersion), holding temperature (4 oC and 8 oC), and holding time (4 h, 8 h, and 12 h) on the physicochemical and sensorial properties of Japanese quail (Coturnix japonica) breast fillets. Ninety-six deboned breast fillets (mean weight ± SD; 10 g ± 2) from 42-day-old unsexed Japanese quails were marinated. Injection marination showed the highest uptake (p < 0.05). The method × temperature × time interaction (p < 0.05) was significant for cooking yield, meat pH, hardness, cooking loss, and surface color lightness (L*). The highest pH (p < 0.05) was reported when the unmarinated control was retained for 8 h. Tumbling marinated meat when held for 12 h at 8 oC yielded the maximum cooking yield (60.3%). The cooking loss was minimal in unmarinated, tumbled, and immersion-marinated meat when held for 12 h. Irrespective of the temperature, 4-h holding time caused the minimum meat hardness in all four treatments. Tumble-marinated meat when held for 12 h at 8 oC resulted in the minimum cooking loss, hardness, and lightness (L*), as well as the maximum cooking yield. Meat when held at 4 oC for 4 h following injection marination had the highest scores for color, aroma, marinade penetration, flavor, and overall acceptability. In conclusion, quail breast fillets when tumble-marinated and held at 8 oC for 12 h were the best in terms of overall meat quality. Quail breast fillets held for 4 h at 4 oC following injection marination were rated highest by the panelists.

Are Lagrangians Involving Fractional Derivatives Physically Viable?, Nicola Fabiano

Turkish Journal of Physics

The recent trend of incorporating fractional derivatives into Lagrangians prompts a critical assessment of their physical viability. This work analyzes such theories through the lenses of classical mechanics and quantum field theory (QFT), revealing profound foundational issues. While the nonlocal nature of fractional operators circumvents Ostrogradsky's theorem, it introduces more severe problems. Classically, these include a complicated variational principle and the violation of energy conservation due to broken time-translation symmetry. In QFT, the pathologies are fatal: the propagator violates the K\"all\'en--Lehmann spectral representation, leading to acausal propagation, ghost states, complex poles, and a loss of unitarity. We conclude that Lagrangians …

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Turkish Journal of Physics

No abstract provided.

Electron-Loss And Electron-Capture Cross Sections In  H + H₂⁺ Collisions, Saed J. Al Atawneh, Oqlah Al-Refai, Mohammed Abu-Seileek, Feras Afaneh

Turkish Journal of Physics

We investigate projectile electron-loss, target electron-loss, and target electron capture in H + H₂⁺ collisions using classical trajectory Monte Carlo (CTMC) and quantum-corrected classical trajectory Monte Carlo (QCTMC) methods within a fully four-body model. Energy-dependent cross sections are reported for all three channels. For projectile electron-loss, we additionally analyze impact-parameter-dependent probabilities and representative trajectories. The QCTMC method incorporates Heisenberg corrections, improving accuracy at low impact energies. Projectile and target electron-loss cross sections peak at intermediate energies and exhibit good agreement with H + H₂⁺ data at high energies. At low to intermediate energies, projectile electron-loss exceeds target electron-loss because the …

Nonlinear Mode Crossing And Spontaneous Frequency Comb Generation In Driven Magnetic Nanodisks, Hasan Pi̇şki̇n

Turkish Journal of Physics

Nonlinear magnetization dynamics in confined nanostructures provide a rich platform for fundamental studies and advanced spintronic applications. Here, we investigate the driven dynamics of a perpendicularly magnetized permalloy nanodisk using high-resolution micromagnetic simulations. In the linear regime, geometric confinement quantizes the uniform precession into discrete radial standing spin-wave (SSW) modes. As the excitation amplitude increases, the fundamental Kittel mode exhibits a pronounced nonlinear frequency shift relative to the higher-order SSW modes, ultimately leading to a critical mode crossing associated with nonlinear resonance overlap and the breakdown of modal orthogonality. Time-domain analysis reveals that strong mode hybridization governs the ensuing dynamics, …

Microscopic Study Of Β-Decay And Stellar Weak Rates In Neutron-Rich Scandium Isotopes, Wajeeha Khalid, Jameel-Un Nabi, Maria Ramzan

Turkish Journal of Physics

This study provides a critical investigation of the β-decay characteristics of neutron-rich scandium isotopes (53-65Sc) using the proton-neutron quasiparticle random phase approximation (pn-QRPA) model. The theoretical framework allows for a microscopic understanding of spin-isospin excitation modes that are essential for examining weak interaction phenomena. Charge-changing Gamow-Teller (GT) strength distributions were calculated and found to agree well with existing experimental results, thereby confirming the model's capacity to accurately represent the nuclear configuration of these isotopes. The computed β-decay half-lives and corresponding log ft values exhibit good agreement with experimental data, further validating the GT strength distributions and reinforcing the consistency of …

Comparison Of Umbral Dot Physical Properties In Developed And Undeveloped Sunspots, Muhammed Ali̇ Çalişir, Ali̇ Kilçik, Vasyl Yurchyshyn

Turkish Journal of Physics

Sunspots are cool regions where the magnetic field is significantly stronger than in the surrounding photosphere, and their darkest central regions are known as the umbra. Umbral dots (UDs) are small, bright features within the umbra that represent convective motions partially suppressed by strong magnetic fields. In this study, high-resolution images from the Goode Solar Telescope (GST) at Big Bear Solar Observatory (BBSO) were used to analyze four sunspots at different evolutionary stages, including two developed and two undeveloped sunspots. The physical properties of UDs, including brightness, diameter, eccentricity, lifetime, and dynamic velocity, were measured and compared across these sunspots …

Stress–Strain Behavior Of The High-Entropy Cantor Alloy Crmnfeconi Using A Deep Neural Network Potential, Nguyen Le Hoai Phuong, Le Huu Nghia, Huynh Khanh Van, Vo Khuong Dien, Nguyen Thanh Tien

Turkish Journal of Physics

Machine learning interatomic potentials (MLIPs) provide an efficient approach to large-scale molecular dynamics simulations of high-entropy alloys. In this work, an MLIP trained on AIMD data was developed for the CrMnFeCoNi Cantor alloy and validated against DFT calculations. In addition, we compared MLIP results with those obtained using the classical modified embedded atom method (MEAM)-based interatomic potential for the CrMnFeCoNi Cantor alloy. The model achieved energy and force RMSEs of 7.39 x 10-6 meV/atom and 4.46 x 10-3 eV/A, respectively. Tensile simulations demonstrated that the MLIP accurately reproduced the stress–strain response, elastic constants, and deformation mechanisms observed in DFT calculations. …

Spacer-Mediated Gold Nanocube Arrays For Edge-Localized Excitonic Enhancement In Monolayer Mos2​, Abdullah Efe Yildiz, Emre Ozan Polat

Turkish Journal of Physics

Plasmonic nanostructures offer an effective route for enhancing light-matter interaction in atomically thin semiconductors, whose optical response is intrinsically limited by their subnanometer active thickness. Here, we numerically investigate excitonic enhancement in monolayer (ML) Molybdenum Disulfide (MoS2) coupled to size-tuned gold (Au) nanocube arrays separated by thin aluminum oxide (Al2O3) and hexagonal boron nitride (h-BN) spacer layers. By varying the nanocube side length, the localized surface plasmon resonance is tuned across the visible spectral range to modulate the A- and B-excitonic transitions of monolayer MoS2.We show that the nanocube-size-dependent spectral redshift can be further controlled through the spacer material and …

Theoretical Construction Of Light Hexaquarks And Their Substantiation By Seven-Dimensional Representation Of Su(2) Group, Mayank Joshi, Shuchi Bisht, Navjot Hothi, Manish Bisht

Turkish Journal of Physics

This manuscript presents a theoretical approach to constructing light hexaquarks using up and down quarks. These light exotic hexaquarks are shown to exhibit a seven-dimensional representation of the SU(2) isospin group. Additionally, the isospin septuplet is developed along with the quintet, triplet, and singlet representations for these light exotic hexaquarks. These particles are essentially mesonic in nature and also satisfy the requirements of the Kronecker product. Furthermore, the physical characteristics and weights of the respective states are intrinsically provided for these light hexaquarks.

Selective Citation: The Systematic Omission Of Established Regional Literature, İrem Eli̇tez

Turkish Journal of Earth Sciences

No abstract provided.

Integrated Assessment Of Groundwater Quality And Human Health Risks In A Semiarid Region Of Kemaliye (Türkiye), Veli̇ Keski̇n, Celaletti̇n Şi̇mşek

Turkish Journal of Earth Sciences

In this study, the hydrochemical characteristics, drinking water suitability, and potential human health risks of groundwater in the Karapınar region (Kemaliye, Erzincan, Türkiye), which has become a critical drinking water resource due to drought associated with climate change and the depletion of surface water resources, were investigated using an integrated multiparameter approach. Within the scope of the study, a total of 18 water samples, comprising 13 spring water samples and 5 groundwater samples obtained from wells, were collected during the dry season (October 2021) and analyzed for major ions, physicochemical parameters, nitrate, and trace elements. The suitability of the samples …

Signals In The Ionosphere Ahead Of Tsunami Arrival, Svetlana Riabova, Sergey Shalimov

Turkish Journal of Earth Sciences

We consider the impact of the tsunami propagating after the earthquake in Tohoku on the ionosphere according to measurements from the Hawaiian Islands, i.e., at a fairly large distance from the epicenter of the earthquake. These measurements, taken at a tidal tsunami monitoring station, at a magnetometric station, and by GPS, were used to record the arrival of the tsunami. We experimentally establish that the arrival of atmospheric waves generated by the tsunami significantly advanced the arrival of sea waves at the observation point, and this advance from one source was recorded in both the lower and upper ionosphere. Attention …

Editorial Note To The Article “Identification Of A Previously Unrecognized Listric Fault Beneath The Acıpayam Graben: Insights From Integrated Dinsar And Field Observations” [Turkish Journal Of Earth Sciences 35 (1) 2026 20-41], Orhan Tatar

Turkish Journal of Earth Sciences

No abstract provided.

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Turkish Journal of Earth Sciences

No abstract provided.

Possible Fluid Contributions From Active Faults To Mercury Distribution In Surface Sediments Of The Gemlik Gulf And Health Risk Assessment, Erol Sari, M. Namik Çağatay, Tuğçe Nagi̇han Arslan Kaya, Zeynep Çeti̇n, Nuray Çağlar

Turkish Journal of Earth Sciences

The Gemlik Gulf, located in the eastern part of the Sea of Marmara (Türkiye), is recognized as a relatively contaminated marine environment, influenced by a variety of natural and anthropogenic inputs. A comprehensive geochemical study was performed to examine the distribution of total mercury (THg) in surface sediments and to elucidate the possible sources contributing to its accumulation. The analysis revealed that THg concentrations ranged from 485 to 6486 ng/g, with all measured values substantially exceeding the average shale background concentration of 400 ng/g, indicating significant enrichment. According to sediment quality guidelines, none of the samples exceeded the effects range …

Paleoecology Of Loftusia Species (Large Benthic Foraminifera) In The Zagros Basin, North Of The Neotethys, Hossein Ghanbarloo, Amrollah Safari

Turkish Journal of Earth Sciences

Paleoecological analyses based on the wall structure of the genus Loftusia were carried out in the Maastrichtian deposits of seven outcrops of the Zagros Basin. Two types of particles are present within the wall structure: (1) tiny fossil grains and (2) detrital grains. Tiny fossil grains consist of smaller foraminifera and other small microorganism tests. Foraminiferal tests are associated with miliolid, textulariid, and rotaliid forms. Detrital grains include intraclasts and extraclasts. The presence of different particles in the test wall of this genus and the abundance of this genus in nutrient-rich conditions indicate that Loftusia are probably opportunistic foraminifera. This …

Neoproterozoic Uranium-Mineralized Sedimentary Rocks From The Kaladgi Basin, Dharwar Craton, Southwestern India: Source And Transport Mechanism Of Uranium, Ponnalagu Govindaraj, Arumugam Shanmugasundaram, Sooriamuthu Ramasamy, Muthusamy Ravichandran

Turkish Journal of Earth Sciences

The Kaladgi Basin of the Dharwar Craton, southeast India, hosts Proterozoic unconformity-related uranium (U) mineralization controlled by faulted contacts between Archean basement and Proterozoic cover sediments. To understand the ore-forming processes, 25 core samples from the Cave Temple Arenite were analyzed using whole-rock geochemistry and fluid inclusion microthermometry. U concentrations reach up to 0.13% U3O8 in the basal arenite and lower conglomerate, whereas the basement schist records only 0.0017% U. Whole-rock data reveal high SiO2 contents (72–97 wt.%), variable Al2O3 (0.4–12.9 wt.%), and enrichments in U (0.38–6.63 ppm), Th (1.5–13.7 ppm), and trace elements such as Cu, Pb, and Ni …

Citation Scope And Scientific Relevance In An Event-Based Seismotectonic Study: Reply To The Comment By Elitez On Eski (2026), Semi̇h Eski̇

Turkish Journal of Earth Sciences

No abstract provided.