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Hyoscine-N-Butylbromide In Treating Abdominal Pain Caused By Gastroenteritis: A Double-Blind Randomized Placebo Controlled Study, Çağdaş Yildirim, Gül Pamukçu Günaydin
Hyoscine-N-Butylbromide In Treating Abdominal Pain Caused By Gastroenteritis: A Double-Blind Randomized Placebo Controlled Study, Çağdaş Yildirim, Gül Pamukçu Günaydin
Turkish Journal of Medical Sciences
Background/aimHyoscine-N-Butylbromide (HBB) is an anticholinergic agent widely used to treat pain caused by spasms in the gastrointestinal and urogenital systems. The aim of this study was to compare the efficacy of HBB with placebo in treating abdominal cramping pain caused by acute gastroenteritis in the Emergency Department (ED).Materials and methodsThis was a prospective, double-blind, placebo-controlled, randomized trial conducted in a single-center academic ED, from September to November 2021. Patients aged 18-65 years with acute gastroenteritis symptoms included in the study. The study compared the efficacy of intravenous HBB (20 mg) with placebo. The primary outcome was the absolute change in …
Antifibrotic Treatment Response Comparison Of Progressive Pulmonary Fibrosis And Idiopathic Pulmonary Fibrosis, Berna Akinci Özyürek, Kerem Ensari̇oglu, Tugce Sahi̇n Ozdemi̇rel, Esma Sevi̇l Akkurt, Ozlem Ozdag, Esma Zenbi̇lli̇
Antifibrotic Treatment Response Comparison Of Progressive Pulmonary Fibrosis And Idiopathic Pulmonary Fibrosis, Berna Akinci Özyürek, Kerem Ensari̇oglu, Tugce Sahi̇n Ozdemi̇rel, Esma Sevi̇l Akkurt, Ozlem Ozdag, Esma Zenbi̇lli̇
Turkish Journal of Medical Sciences
Background/Aim: Idiopathic pulmonary fibrosis (IPF) and progressive pulmonary fibrosis (PPF) are two entities categorized fibrotic lung diseases. With a similar clinical presentation and treatment modalities in many cases, the line differentiating two diseases may not be evident. We aimed to evaluate the effectiveness of antifibrotic treatment and the course of fibrotic lung diseases. Material and Methods: The study included patients diagnosed with IPF and PPF who were given antifibrotic treatment and followed up for one year in our clinic. At one year, treatment response and radiological evaluation were investigated by high-resolution computed tomography. Results: Eighty-seven patients were included in the …
Blood Component-Associated Acute Transfusion Reactions In Pediatric Patients: Experience Of A Tertiary Care Hospital, Zeli̇ha Guzelkucuk, Di̇lek Gurlek Gokcebay, Turan Bayhan, Ikbal Ok Bozkaya, Ozlem Arman Bi̇li̇r, Vi̇ldan Kosan Culha, Melek Isik, Ayca Koca Yozgat, Husni̇ye Nese Yarali, Nami̇k Yasar Ozbek
Blood Component-Associated Acute Transfusion Reactions In Pediatric Patients: Experience Of A Tertiary Care Hospital, Zeli̇ha Guzelkucuk, Di̇lek Gurlek Gokcebay, Turan Bayhan, Ikbal Ok Bozkaya, Ozlem Arman Bi̇li̇r, Vi̇ldan Kosan Culha, Melek Isik, Ayca Koca Yozgat, Husni̇ye Nese Yarali, Nami̇k Yasar Ozbek
Turkish Journal of Medical Sciences
Background/aimTransfusion of blood products is a life-saving clinical practice in patients with bleeding, hemoglobinopathy and cancer. In this study, we aimed to analyze the frequency and types of blood component-related acute transfusion reactions (ATR) in pediatric patients.Materials and methodsThis retrospective study was conducted at a tertiary care academic pediatric hospital.ResultsDuring the study period, 30,811 transfusions were administered to 25,448 patients. 103 ATRs were detected in 81 patients (0.33%; 3.34 reactions per 1000 transfusions, mean age 8.3±5.98 years, F/M: 36/45). All reactions were observed within an average of 4 hours after the start of the transfusion. The most common ATRs were …
Internalizing Disorders Rather Than Adhd Are Risk Factors For Chronicity In Pediatric Migraine Patients, Nevra Öksüz, Gülen Güler Aksu, Asena Ayça Özdemi̇r, Aynur Özge
Internalizing Disorders Rather Than Adhd Are Risk Factors For Chronicity In Pediatric Migraine Patients, Nevra Öksüz, Gülen Güler Aksu, Asena Ayça Özdemi̇r, Aynur Özge
Turkish Journal of Medical Sciences
Background/aim: Migraine is a prevalent neurological disorder that can lead to disability in children and adolescents. It is frequently accompanied by psychiatric comorbidities, both internalizing and externalizing disorders. While the relationship between migraine and internalizing disorders has been studied, there is limited research on the link between migraine and attention deficit hyperactivity disorder (ADHD).Materials and methods: A total of 280 pediatric headache patients, 107 with externalizing (ADHD) and 173 with internalizing disorders (depression and/or anxiety), were included. The dataset was composed using the Turkish headache database, Mersin Branch. Pain characteristics, associated symptoms, and accompanying comorbidities were evaluated retrospectively.Results: Two hundred …
A Nationwide Study: Prevalence Of Rheumatoid Factor And Anti- Citrullinated Peptide Positivity And Their Contribution To Rheumatoid Arthritis Diagnosis, Hasan Satiş, Abdulsamet Erden, Emre Bi̇lgi̇n, Gi̇zem Ayan, Berkan Armağan, Duygu Tecer, Alper Sari, Umut Kalyoncu, Murat Çağlayan, Mustafa Mahi̇r Ülgü, Mustafa Okan Ayvali, Nai̇m Ata, Şuayi̇p Bi̇ri̇nci̇
A Nationwide Study: Prevalence Of Rheumatoid Factor And Anti- Citrullinated Peptide Positivity And Their Contribution To Rheumatoid Arthritis Diagnosis, Hasan Satiş, Abdulsamet Erden, Emre Bi̇lgi̇n, Gi̇zem Ayan, Berkan Armağan, Duygu Tecer, Alper Sari, Umut Kalyoncu, Murat Çağlayan, Mustafa Mahi̇r Ülgü, Mustafa Okan Ayvali, Nai̇m Ata, Şuayi̇p Bi̇ri̇nci̇
Turkish Journal of Medical Sciences
AbstractAim: Rheumatoid factor (RF) and Anti Citrullinated Peptide (anti-CCP) is specific for rheumatoid arthritis (RA) diagnosis. However they could be positive in other disease and even healthy populations. It was aimed to investigate the prevalence of positive RF and anti-CCP antibodies in persons admitted to hospital for any reason and on a national scale.Material and Method: The National Electronic Health Database, which contains the clinical records of over eighty million people, is used to design this multi-center, retrospective cohort study. The subjects included in the study were divided into age groups in 10-year periods. RA cases were identified by using …
Psychometric Properties Of The Turkish Version Of The Vestibular Migraine Patient Assessment Tool And Handicap Inventory, Deni̇z Uğur Cengi̇z, Feyza İnceoğlu, Ercan Karababa, Bülent Satar, Hati̇ce Seyra Erbek, Tuba Bayindir, Büşra Kurtcu, Sanem Can Çolak, Mehmet Kadi̇r Ercan, Emre Söylemez, Meti̇n Yüksel Akyildiz, Yüce İslamoğlu, Bengi̇ Arslan, Sümeyye Demi̇rel Bi̇ri̇şi̇k, Emre Akgün Özdemi̇r, İsmai̇l Demi̇r, Ahmet Adigüzel
Psychometric Properties Of The Turkish Version Of The Vestibular Migraine Patient Assessment Tool And Handicap Inventory, Deni̇z Uğur Cengi̇z, Feyza İnceoğlu, Ercan Karababa, Bülent Satar, Hati̇ce Seyra Erbek, Tuba Bayindir, Büşra Kurtcu, Sanem Can Çolak, Mehmet Kadi̇r Ercan, Emre Söylemez, Meti̇n Yüksel Akyildiz, Yüce İslamoğlu, Bengi̇ Arslan, Sümeyye Demi̇rel Bi̇ri̇şi̇k, Emre Akgün Özdemi̇r, İsmai̇l Demi̇r, Ahmet Adigüzel
Turkish Journal of Medical Sciences
Background/aimThere are insufficient tools to assist in the diagnosis and treatment of vestibular migraine. The aim of the study to perform the Turkish adaptation of the Vestibular Migraine Patient Assessment Tool and Handicap Inventory (VM-PATHI).Materials and methodsAfter language and content validity was completed, a pilot study was conducted. Exploratory and confirmatory factor analyzes were conducted to test construct validity, and as a result of validity analyses, Cronbach α internal consistency coefficient and test-retest analyzes were conducted for reliability.ResultsIn the study in which 289 participants were evaluated, the Kaiser-Meyer-Olkin coefficient was calculated as 0.903. The percentage of variance explained by the …
Evaluation With Structural Equation Modeling Of Variables Affecting Health-Seeking Behaviors During The Covid-19 Pandemic In İstanbul, Türkiye, Pinar Atali, Seyhan Hidiroğlu, Ali̇can Sarisaltik, Melda Karavuş
Evaluation With Structural Equation Modeling Of Variables Affecting Health-Seeking Behaviors During The Covid-19 Pandemic In İstanbul, Türkiye, Pinar Atali, Seyhan Hidiroğlu, Ali̇can Sarisaltik, Melda Karavuş
Turkish Journal of Medical Sciences
Background/aim: The relation between the demographic characteristics of individuals and their health-seeking behaviors was presented and the effects of health cognitions, healthy lifestyle behaviors, and coronavirus fear levels on health-seeking behaviors during the COVID-19 pandemic were examined.Materials and methods: This descriptive survey study was conducted in the Tuzla District of İstanbul, Türkiye, between March and June 2021. Results: From analysis of the 391 participants, 60.0% were females, 27.1% were between 31 and 40 years of age, 47.0% were healthcare professionals, and the perceived socioeconomic status of 50.9% was above average. According to the results, the women exhibited more health-seeking behavior …
Comparison Of Combined Deep And Superficial Serratus Anterior Block With Thoracic Paravertebral Block For Postoperative Pain In Patients Undergoing Video-Assisted Thoracoscopic Surgery, Gülay Ülger, Musa Zengi̇n, Onur Küçük, Ramazan Baldemi̇r, Oya Kaybal, Mehtap Tunç, Hi̇lal Sazak, Ali̇ Alagöz
Comparison Of Combined Deep And Superficial Serratus Anterior Block With Thoracic Paravertebral Block For Postoperative Pain In Patients Undergoing Video-Assisted Thoracoscopic Surgery, Gülay Ülger, Musa Zengi̇n, Onur Küçük, Ramazan Baldemi̇r, Oya Kaybal, Mehtap Tunç, Hi̇lal Sazak, Ali̇ Alagöz
Turkish Journal of Medical Sciences
Background/aim: Thoracic paravertebral block (TPVB) is a well-established procedure for the management of postoperative pain in patients undergoing video-assisted thoracic surgery (VATS). In recent years, there have been studies suggesting that fascial plane blocks may be an alternative to TPVB. The objective of this study is to determine the efficacy of combined deep and superficial serratus anterior block (C-SAPB) as an alternative to TPVB in the management of postoperative analgesia in VATS.Materials and methods: The patients were divided into two groups: TPVB and C-SAPB. Both groups were administered the same dose of local anesthetics. Multimodal analgesia was achieved for the …
Predictive Value Of Preoperative Fried Frailty Phenotype Assessment And Serum Biomarkers On The Prognosis Of Elderly Patients With Femoral Neck Fracture Under General Anesthesia Within 3 Months After Surgery, Fu Xu, Xin Kuang, Baofeng Cao, Yang Yue
Predictive Value Of Preoperative Fried Frailty Phenotype Assessment And Serum Biomarkers On The Prognosis Of Elderly Patients With Femoral Neck Fracture Under General Anesthesia Within 3 Months After Surgery, Fu Xu, Xin Kuang, Baofeng Cao, Yang Yue
Turkish Journal of Medical Sciences
Background/aim: Femoral neck fracture (FNF) seriously impact the health of the elderly and affect their long-term quality of life of the patients. This study aimed to determine whether combining the preoperative Fried Frailty Phenotype (FFP) with serum fibroblast growth factor receptor 3 (FGFR3) and run-related transcription factor 2 (RUNX2) could better predict the prognosis of elderly patients with FNF 3 months after surgery.Materials and methods: A total of 150 elderly patients with FNF (60–89 years old) were enrolled and divided into a nonfrailty cohort and a frailty cohort based on preoperative FFP evaluation. The hip recovery of patients 3 months …
Trend Shift In Proximal Humeral Fracture Treatment: A Detailed Review Of National Shoulder Arthroplasty Data, İbrahi̇m Bozkurt, İbrahi̇m Kaya, Umut Öktem, Si̇nan Yilmaz, Nai̇m Ata, Mustafa Mahi̇r Ülgü, Şuayi̇p Bi̇ri̇nci̇, Fati̇h Karaaslan, İzzet Bi̇ngöl, Durmuş Ali̇ Öçgüder
Trend Shift In Proximal Humeral Fracture Treatment: A Detailed Review Of National Shoulder Arthroplasty Data, İbrahi̇m Bozkurt, İbrahi̇m Kaya, Umut Öktem, Si̇nan Yilmaz, Nai̇m Ata, Mustafa Mahi̇r Ülgü, Şuayi̇p Bi̇ri̇nci̇, Fati̇h Karaaslan, İzzet Bi̇ngöl, Durmuş Ali̇ Öçgüder
Turkish Journal of Medical Sciences
Background/aim: This study is aimed to scrutinize the nationwide utilization trends of shoulder arthroplasty for proximal humerus fractures (PHFs), using a comprehensive national surgical database.Materials and methods: A retrospective study was conducted with 4181 patients who underwent shoulder arthroplasty due to PHF between 2016 and 2022 using national health records. They are grouped as hemiarthroplasty (HA), anatomical total shoulder arthroplasty (TSA) and reverse shoulder arthroplasty (RSA). The patients’ demographic data, hospitalization period, revision history, transfusion rates, mortality data, distribution of trends in arthroplasty methods by years, distribution of cases according to hospital characteristics, and geographical regions , were analyzed.Results: 22.1% …
Comparison Of Treatment Methods In Patients With Developmental Dysplasia Of The Hip, Burhan Kurtuluş
Comparison Of Treatment Methods In Patients With Developmental Dysplasia Of The Hip, Burhan Kurtuluş
Turkish Journal of Medical Sciences
Background/aimThe aim of this study is to compare the results of pemberton osteotomy (PO), salter innominate osteotomy (SO), open reduction (OR) and closed reduction (CR) applied in the treatment of Developmental Dysplasia of the Hip (DDH).Materials and methods101 hips of 82 patients treated at Orthopedic Clinic between 2017 and 2023 were included in the study. Preoperatively, postoperatively and at final follow-up of patients were evaluated. The results of these patients were evaluated according to Severin's radiological and Barret's clinical classifications. Patients who developed avascular necrosis (AVN) were evaluated according to the Bucholz and Ogden classification.ResultsIn terms of preoperative acetabular angle …
Open Surgical Approach To Fractures Of The Mandibular Condyle: Surgical Technique And Associated Complications, Cenk Demi̇rdover, Alper Geyi̇k
Open Surgical Approach To Fractures Of The Mandibular Condyle: Surgical Technique And Associated Complications, Cenk Demi̇rdover, Alper Geyi̇k
Turkish Journal of Medical Sciences
Background/aim: This study evaluates anatomical reduction and rigid internal fixation of mandibular condyle fractures using the preauricular retroparotid approach. It also, discusses advantages, deficiencies, and associated complications of the technique.Materials and methods: This retrospective study reviewed the medical records of a total of 52 mandibular condyle fractures, from 42 patients, who treated with open surgical approach using the preauricular retroparotid approach between January 2019 and 2024. Preoperative and postoperative assessments included measurements of mouth opening (maximum interincisal distance), vertical mandibular movement and facial paralysis. Moreover, the Vancouver Scar Scale (VSS) was used to evaluate scar quality at the surgical site. …
Production And Characterization Of Zn- And Cu-Doped Y2o3–Al2o3–Sio2 (Yas) Glass Microspheres, Fatma Unal, Batur Ercan
Production And Characterization Of Zn- And Cu-Doped Y2o3–Al2o3–Sio2 (Yas) Glass Microspheres, Fatma Unal, Batur Ercan
Turkish Journal of Medical Sciences
Background/aim: YAS glass microspheres are currently used in radioembolization treatment. However, abscess formation can occur following this treatment. The aim of this study is to endow YAS glass microspheres with antibacterial properties to address the abscesses that form in patients after radioembolization treatment.Materials and methods: In this study, undoped Y2O3–Al2O3–SiO2 (YAS) glass microspheres, as well as those doped with antibacterial agents zinc (Zn) and/or copper (Cu), were successfully fabricated using a sol-gel derived method.Results: After heat treatment, the microspheres exhibited an amorphous structure. Additionally, the incorporation of Zn and/or Cu dopants did not alter the patterns observed in the X-ray …
Determining Risk Factors Influencing Substance Use Among Turkish-Origin Immigrants In Germany, Enes Efendi̇oğlu, Lütfi̇ye Hi̇lal Özcebe
Determining Risk Factors Influencing Substance Use Among Turkish-Origin Immigrants In Germany, Enes Efendi̇oğlu, Lütfi̇ye Hi̇lal Özcebe
Turkish Journal of Medical Sciences
BackgroundThe increasing international migration poses unique challenges, especially regarding health outcomes and behaviors such as substance use. This study focuses on identifying risk factors influencing substance use among Turkish-origin immigrants in Germany.Materials and MethodsData were sourced from the STEPS survey conducted by the Presidency for Turks Abroad and Related Communities (YTB) in 2021 in Germany. A total of 1157 participants were selected through a quota sampling method. Data analysis involved descriptive statistics and logistic regression, utilizing SPSS 21 software.ResultsThe study found a significant association between substance use and variables such as generation status, age, and gender. Third-generation immigrants showed a …
Vitamin D3 Alleviates Intestinal Injury In Necrotizing Enterocolitis And Lipopolysaccharide-Induced Inflammatory Response In Dendritic Cells In Rats, Bo Ke, Chaoyu Li, Song Li, Jingjing Yan, Leke Sun
Vitamin D3 Alleviates Intestinal Injury In Necrotizing Enterocolitis And Lipopolysaccharide-Induced Inflammatory Response In Dendritic Cells In Rats, Bo Ke, Chaoyu Li, Song Li, Jingjing Yan, Leke Sun
Turkish Journal of Medical Sciences
Background/aim: Necrotizing enterocolitis (NEC) is a serious condition that predominantly affects premature infants and involves an aberrant immune response and inflammatory cytokine release resulting in intestinal epithelial damage. The current study investigated the immunoregulatory effects of vitamin D3 on the maturation and activation of dendritic cells (DCs) and the antiinflammatory impact on the intestines in a neonatal rat model of NEC.Materials and methods: Inflammatory damage to intestinal tissue was assessed via morphological changes and apoptosis and DC expression of costimulatory molecules, inflammatory factors, and immunoregulatory factors by immunohistochemical staining, quantitative real-time PCR, and immunofluorescence. The fluorescein isothiocyanate-ovalbumin (FITC-OVA) uptake assay …
Comparison Of Autologous Venous Grafts And Three Types Of Extracellular Matrix Grafts In Peyronie’S Disease Surgery, Türker Soydaş, Selman Ünal, Hali̇l Uzundal, Merve Kaşikci, Musab Ali̇ Kutluhan, Emrah Okulu, Önder Kayigi̇l
Comparison Of Autologous Venous Grafts And Three Types Of Extracellular Matrix Grafts In Peyronie’S Disease Surgery, Türker Soydaş, Selman Ünal, Hali̇l Uzundal, Merve Kaşikci, Musab Ali̇ Kutluhan, Emrah Okulu, Önder Kayigi̇l
Turkish Journal of Medical Sciences
Background/aimPeyronie's Disease (PD) is known as a wound-healing disorder, for which surgery remains the gold standard treatment, but studies comparing graft materials are few in the literature. The aim of this study is to evaluate the mid- and long-term results of patients who had Peyronie's surgery with grafting procedures performed by a single experienced surgeon, according to the graft materials.Materials and methodsPatients who underwent corporoplasty between 2014 and 2020 with grafting procedures by a single experienced surgeon were retrospectively reviewed. 115 patients were divided into 4 groups according to the graft material used: autologous saphenous venous graft, Group 1 (n=36); …
Association Between Systemic Zinc And Oxidative Stress Levels And Periodontal Inflamed Surface Area, Ayşegül Sari, Serdar Doğan, Luigi Nibali
Association Between Systemic Zinc And Oxidative Stress Levels And Periodontal Inflamed Surface Area, Ayşegül Sari, Serdar Doğan, Luigi Nibali
Turkish Journal of Medical Sciences
Background/aim: Zinc is a structural component of some enzymes. The aim of this study was to evaluate the potential associations between serum zinc and oxidative stress levels and periodontal inflamed surface area (PISA).Materials and methods: This study included 90 patients divided into three groups: a periodontitis group (P; n = 30), a gingivitis group (G; n = 30), and a periodontal health group (PH; n = 30). Periodontal parameters were recorded and PISA values were calculated. Serum total antioxidant status (TAS), total oxidant status (TOS), and zinc levels were examined biochemically. Oxidative stress index (OSI) levels were calculated.Results: All clinical …
Are There Differences In The Clinical And Laboratory Features Of Patients With Seronegative Primary Sjögren's Syndrome?, Müçteba Enes Yayla, Rahi̇me Aksoy, Emi̇ne Uslu, Zehra Karaman, Recep Yilmaz, Ahmet İlbay, Ni̇lgün Göveç Giynaş, Abdulbaki̇ Gaydan, Ahmet Usta, Yeter Mahmutoğlu, Aşkin Ateş, Murat Turgay
Are There Differences In The Clinical And Laboratory Features Of Patients With Seronegative Primary Sjögren's Syndrome?, Müçteba Enes Yayla, Rahi̇me Aksoy, Emi̇ne Uslu, Zehra Karaman, Recep Yilmaz, Ahmet İlbay, Ni̇lgün Göveç Giynaş, Abdulbaki̇ Gaydan, Ahmet Usta, Yeter Mahmutoğlu, Aşkin Ateş, Murat Turgay
Turkish Journal of Medical Sciences
Background/aim: The primary objective of this study was to demonstrate the commonalities and distinctions between patients with seronegative and seropositive primary Sjögren's syndrome (pSS).Materials and methods: Between January 2010 and June 2023, 399 pSS were retrospectively examined. Patients with negative anti-SSA/Ro, anti-SSB/La, ANA, and RF antibodies comprised the seronegative group, while patients with at least one antibody positivity classified the seropositive group.Results: The most common clinical features were arthralgia (81.2%), arthritis (11.5%), hematological (19.8%) and pulmonary (11.8%) involvement. In 41 patients (10.3%), no autoantibody positivity was detected. The number of patients with at least one extraarticular involvement was statistically more …
Telemedicine In Pediatric Rheumatology: The Video Pediatric Gait, Arms, Legs, And Spine (V-Pgals), Zeynep Balik, Seher Şener, Yağmur Bayindir, Müşerref Kasap Cüceoğlu, Emi̇l Ali̇yev, Özge Başaran, Yelda Bi̇lgi̇ner, Seza Özen, Ezgi̇ Deni̇z Batu
Telemedicine In Pediatric Rheumatology: The Video Pediatric Gait, Arms, Legs, And Spine (V-Pgals), Zeynep Balik, Seher Şener, Yağmur Bayindir, Müşerref Kasap Cüceoğlu, Emi̇l Ali̇yev, Özge Başaran, Yelda Bi̇lgi̇ner, Seza Özen, Ezgi̇ Deni̇z Batu
Turkish Journal of Medical Sciences
Background/aim: Video pediatric gait, arms, leg, and spine (v-pGALS) is a virtual application of pediatric gait, arms, leg, and spine (pGALS) examination performed by video. We aimed to verify the applicability, validity, and accuracy of the Turkish translation of the v-pGALS in a large pediatric patient cohort.Materials and methods: Children aged 4-18 years were included between May and June 2022. A hands-on physical examination and v-pGALS were performed. Demographics, active symptoms, physical examination findings, diagnosis, and v-pGALS findings were recorded. The acceptability of v-pGALS by the parent/patient was measured using a visual analog scale (VAS), in terms of additional distress …
The Impact Of Maternal Muscle Strength On Cesarean Delivery Outcomes: A Comparative Study Of Nulliparous Women, Gülsemi̇n Ertürk Çeli̇k, Sezi̇n Ertürk Aksakal, Yaprak Engi̇n Üstün
The Impact Of Maternal Muscle Strength On Cesarean Delivery Outcomes: A Comparative Study Of Nulliparous Women, Gülsemi̇n Ertürk Çeli̇k, Sezi̇n Ertürk Aksakal, Yaprak Engi̇n Üstün
Turkish Journal of Medical Sciences
Arkaplan/amaçAraştırma, doğumda anne kas kütlesi ve gücü ile doğum şekli arasındaki korelasyona odaklandı. Özellikle, nullipar gebe kadınlar terimine odaklandı ve quadriceps femoris kasının ultrasonografik ölçümlerini serum miyostatin seviyeleri ve el sıkma testi ile belirlenen kas gücüyle birlikte analiz etti. Amaç, bu faktörlerin vajinal veya sezaryenle doğum yapma olasılığını etkileyip etkilemediğini ayırt etmekti.Malzemeler ve yöntemlerBu çalışma, 86 sağlıklı, doğum yapmamış kadını, doğum biçimlerine göre iki gruba ayırarak çalışmaya dahil etti: vajinal doğum (58 kadın, Grup 1) ve sezaryen (28 kadın, Grup 2). Demografik bilgiler, doğum özellikleri, quadriceps femoris'in ultrasonografik ölçümleri, uzuv çevreleri, el kavrama gücü ve serum miyostatin konsantrasyonları üzerinde karşılaştırmalı …
Relationship Between Microbiota Awareness, Nutrition Literacy, And Health Literacy Among Adolescents, İzzet Ülker, Muhammet Ali̇ Aydin, Meti̇n Yildiz, Gönül Gökçay, Ayşe Elkoca, Mehmet Sali̇h Yildirim, Abraham Tanimowo, Dursun Alper Yilmaz
Relationship Between Microbiota Awareness, Nutrition Literacy, And Health Literacy Among Adolescents, İzzet Ülker, Muhammet Ali̇ Aydin, Meti̇n Yildiz, Gönül Gökçay, Ayşe Elkoca, Mehmet Sali̇h Yildirim, Abraham Tanimowo, Dursun Alper Yilmaz
Turkish Journal of Medical Sciences
Background/aim: Microbiota awareness, nutritional literacy, and health literacy levels in adolescence have a significant impact on adolescents' health and well-being. This research was conducted to examine the relationship between microbiota awareness, nutrition literacy and health literacy in adolescents.Material and methods: The research was conducted in a descriptive-correlational type. The universe of the research was formed by individuals aged (10-19) living in Türkiye (n:739) between June 2022-February 2024. Data were analyzed using SPSS 22.0, G*Power 3.1, and R programming language 4.1.3 programs.Results: The total effect of the health literacy variable on nutritional literacy was 0.2311, and this effect value was statistically …
Management Of Acute Pain In Adults With Sickle Cell Disease: The Experience Of The Clinical Hematology Department Of The University Of Dakar, Ali̇oune Badara Diallo, Moussa Seck, Mohamed Keita, Sokhna Aissatou Touré, Elimane Seydi Bousso, Baron Ngasia, Blaise Felix Faye, Fatma Dieng, Sali̇ou Diop
Management Of Acute Pain In Adults With Sickle Cell Disease: The Experience Of The Clinical Hematology Department Of The University Of Dakar, Ali̇oune Badara Diallo, Moussa Seck, Mohamed Keita, Sokhna Aissatou Touré, Elimane Seydi Bousso, Baron Ngasia, Blaise Felix Faye, Fatma Dieng, Sali̇ou Diop
Turkish Journal of Medical Sciences
Background/aim: The evolution of sickle cell disease (SCD) is marked by the occurrence of painful episodes linked to the obstruction of micro-vessels by sickle cells, known as vaso-occlusive crises (VOC). The aim of our work was to report the practical aspects of the management of acute pain in adults with SCD. Recommendations based on these practices are also provided.Materials and methods: We conducted a prospective, cross-sectional, descriptive and analytical study over a 4-month period of all sickle cell patients admitted to emergency departments for VOC. The parameters studied were sociodemographic, clinico-biological, therapeutic and evolutionary.Results: 118 cases of VOC were identified, …
Early Re-Laparotomy In Recipients After Living Donor Liver Transplantation: Causes, Risk Factors And Consequences, Bora Barut, Cengi̇z Ceylan, Aki̇le Zengi̇n, Mehmet Güzel, Yasi̇n Dalda, Sezai̇ Yilmaz
Early Re-Laparotomy In Recipients After Living Donor Liver Transplantation: Causes, Risk Factors And Consequences, Bora Barut, Cengi̇z Ceylan, Aki̇le Zengi̇n, Mehmet Güzel, Yasi̇n Dalda, Sezai̇ Yilmaz
Turkish Journal of Medical Sciences
AbstractBackground/aim: Despite advancements in surgical methodologies and the extensive perioperative and postoperative care administered to recipients, the prevalence of complications requiring early re-laparotomy following living donor liver transplantation remains persistent. This investigation seeks to analyze the determinants influencing re-laparotomy occurrences in the initial 30 days following living donor liver transplantation. Additionally, our goal is to evaluate the impact of early laparotomy on both graft and patient survival within this distinct patient cohort.Materials and methods: The study encompassed recipients (n=535) aged 18 years and older who underwent primary living donor liver transplantation at our institution from January 2019 to December 2021. …
Thoracic Trauma In The Geriatric Population And Possible Preventive Measures: A Retrospective Analysis Of 261 Cases, Mehmet Çeti̇n, Necati̇ Solak, Büşra Özdemi̇r Çi̇fli̇k, İlteri̇ş Türk, Sebahatti̇n Sefa Ermancik, Koray Aydoğdu
Thoracic Trauma In The Geriatric Population And Possible Preventive Measures: A Retrospective Analysis Of 261 Cases, Mehmet Çeti̇n, Necati̇ Solak, Büşra Özdemi̇r Çi̇fli̇k, İlteri̇ş Türk, Sebahatti̇n Sefa Ermancik, Koray Aydoğdu
Turkish Journal of Medical Sciences
Background/aim: The rise in the proportion of the elderly population within society is concurrently escalating their vulnerability to traumas, notably falls associated with age-related comorbidities.Materials and Methods: The retrospective analysis involved the examination of data pertaining to patients aged 65 and above who were admitted to our clinic for inpatient treatment following thoracic trauma. Various parameters were statistically compared between the groups with indoor and outdoor traumas.Results: 59.4% of the 261 patients included in the study were male, and the average age in the entire sample was calculated as 75.52±7.79. 136 patients (52%) had indoor trauma, while 125 (48%) had …
Role Of Ct-Based Body Composition Parameters In The Course Of Covid-19, Elçi̇n Aydin, Begüm Ergi̇n, Ezgi̇ Güvel Verdi̇, Özge Coşkun, Şükrü Şahi̇n, Ali̇ Haydar Baykan, Hi̇lal Şahi̇n
Role Of Ct-Based Body Composition Parameters In The Course Of Covid-19, Elçi̇n Aydin, Begüm Ergi̇n, Ezgi̇ Güvel Verdi̇, Özge Coşkun, Şükrü Şahi̇n, Ali̇ Haydar Baykan, Hi̇lal Şahi̇n
Turkish Journal of Medical Sciences
Background/aim: A significant correlation is observed between the course of coronavirus disease 2019 (COVID-19) and body composition parameters including visceral fat quantification, muscle mass, and hepatic attenuation. The aim of the study was to investigate the correlation between the extent of lung involvement and various computed tomography (CT) parameters, as well as laboratory findings in COVID-19 patients.Materials and methods: A retrospective analysis was conducted on 72 adult patients with laboratory-confirmed severe acute respiratory syndrome coronavirus 2 infection who underwent two consecutive thorax CT scans at least 2 weeks apart. The patients were divided into two groups, as progressive and nonprogressive, …
Phthalate Exposure Induces Cell Death And Ferroptosis In Neonatal Microglial Cells, Eli̇f Keleş, Lati̇fe Arzu Aral, Zübeyi̇r Elmazoğlu, Hasan Hüseyi̇n Kazan, Eli̇f Gülçi̇çek Abbasoğlu Topa, Mehmet Ali̇ Ergün, Hayrunni̇sa Bolay
Phthalate Exposure Induces Cell Death And Ferroptosis In Neonatal Microglial Cells, Eli̇f Keleş, Lati̇fe Arzu Aral, Zübeyi̇r Elmazoğlu, Hasan Hüseyi̇n Kazan, Eli̇f Gülçi̇çek Abbasoğlu Topa, Mehmet Ali̇ Ergün, Hayrunni̇sa Bolay
Turkish Journal of Medical Sciences
Background/aim: Phthalates are the materials used for plasticizing polyvinyl chloride. Di-(2-Ethylhexyl) phthalate (DEHP) is one of the most frequently used phthalates in a wide range of applications, including medical equipment such as endotracheal and feeding tubes, intravenous catheters, central lines, extracorporeal membrane oxygenation sets, total parenteral nutrition bags, blood product sets, and intravenous pump lines, respiratory sets in neonatal intensive care units. Studies have shown that phthalates, including DEHP, can cross the placenta and blood-brain barrier, possibly leading to neurodevelopmental impairments in vitro and in vivo. However, the molecular mechanisms affected by phthalate exposure have not been explored in depth. …
Comparison Of Double-Port Laparoscopic-Assisted Extracorporeal Suturing Repair Technique And Open Surgical Repair In Morgagni Hernia, Mehmet Sarikaya, Fatma Ozcan Siki, Meti̇n Gunduz, Tamer Sekmenli, Ilhan Ciftci
Comparison Of Double-Port Laparoscopic-Assisted Extracorporeal Suturing Repair Technique And Open Surgical Repair In Morgagni Hernia, Mehmet Sarikaya, Fatma Ozcan Siki, Meti̇n Gunduz, Tamer Sekmenli, Ilhan Ciftci
Turkish Journal of Medical Sciences
Study's background/aim: We aimed to compare the results of Open surgery and double-port laparoscopic-assisted extracorporeal suturing repair for treating Morgagni hernia (MH).Materials and methods: Twenty-two Patients with MH who were operated on in our clinic between January 2012 and January 2023 were included in the study. Patients were divided into two groups according to the surgical technique: open surgery (OS) (n=14) or laparoscopic surgery (LS) (n=8). Retrospective comparisons were made between the groups' demographic information, surgical method used, defect size, operation time, hospital stay length, cost, postoperative problems, and recurrence. Results: There were no statistically significant differences between the groups …
The Function Of P97/Valosin-Containing Protein (Vcp) And Small Vcp-Interacting Protein (Svip) In Invasion And Migration Of Pancreatic Cancer Cells, Ebru Ali̇moğullari, Sevi̇l Çayli
The Function Of P97/Valosin-Containing Protein (Vcp) And Small Vcp-Interacting Protein (Svip) In Invasion And Migration Of Pancreatic Cancer Cells, Ebru Ali̇moğullari, Sevi̇l Çayli
Turkish Journal of Medical Sciences
Background/aim: Misfolded proteins are eliminated by a process known as Endoplasmic reticulum-associated protein degradation (ERAD). ERAD has an impact on variety of illnesses, such as diabetes, cystic fibrosis, cancer, and neurological conditions. We concentrated on p97/Valosin-containing protein (VCP) and small VCP-interacting protein (SVIP) despite there being many proteins involved in ERAD. The existence and function of SVIP and p97/VCP in various types of pancreatic cancer have not yet been investigated. The study's objectives are to examine the expressions of SVIP and p97/VCP in two pancreatic cancer types and to show whether these proteins aid in the invasion and migration of …
Antimetastatic Effect Of Nanodiamond-Conjugated Quercetin Against Colon Cancer: An In Vivo Study, Firli Rahmah Primula Dewi, Sephia Tiara Marviella, Sri Puji Astuti Wahyuningsih, A'Liyatur Rosyidah, Vuanghao Lim, Lionel Lian Aun In, Amy Yi Hsan Saik, Bimaji Ariyogo, Mee Lee Looi
Antimetastatic Effect Of Nanodiamond-Conjugated Quercetin Against Colon Cancer: An In Vivo Study, Firli Rahmah Primula Dewi, Sephia Tiara Marviella, Sri Puji Astuti Wahyuningsih, A'Liyatur Rosyidah, Vuanghao Lim, Lionel Lian Aun In, Amy Yi Hsan Saik, Bimaji Ariyogo, Mee Lee Looi
Turkish Journal of Biology
Background/aim: Quercetin (Q) is a compound that can inhibit the growth of cancer cells in the colon; however, to do so, a high dose is needed, requiring a drug delivery system to target cancer endothelial cells directly. This study investigates the potency of nanodiamond-conjugated quercetin (NDQ) as an anticancer drug against colon cancer in Rattus norvegicus induced by N-methyl N-Nitrosourea (MNU). Materials and methods: This study is experimental-based and was designed using a six-group treatment method, namely normal control (KN: not treated by MNU, nanodiamond (ND), or Q); negative control (K–: treated by MNU); positive control (K+: treated by MNU …