Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

TÜBİTAK

Discipline
Keyword
Publication Year
Publication

Articles 841 - 870 of 10500

Full-Text Articles in Entire DC Network

Identification And Extraction Method Of Fragrant Pear Based On Image Detection Under Internet Of Things Applications, Peng Zhou, Huan Wnag, Pengwei Zhang, Shengzhi Liu, Wei Cehn, Weihang Zhao, Bingyu Cao Aug 2024

Identification And Extraction Method Of Fragrant Pear Based On Image Detection Under Internet Of Things Applications, Peng Zhou, Huan Wnag, Pengwei Zhang, Shengzhi Liu, Wei Cehn, Weihang Zhao, Bingyu Cao

Turkish Journal of Agriculture and Forestry

With the continuous development of society, agricultural production technology is also improving. Due to the continuous improvement of economic level, the quality of life has also put forward higher requirements, the quality of agricultural products has gradually received more people’s attention. In the picking and sorting process of traditional fragrant pear, the quality control process is not perfect, and the identification and extraction method is not mature enough. In the complex environment of insufficient light or shade of branches and leaves, the pear picking work cannot quickly and accurately locate the target fruit. Therefore, the traditional identification and extraction methods …


Cover And Contents Aug 2024

Cover And Contents

Turkish Journal of Agriculture and Forestry

No abstract provided.


Qtl Mapping For Fatty Acid Composition In Olive Oil Using A High-Density Genetic Map Based On Snp Markers, Ali̇ Can Kaya, Meryem İpek, Ahmet İpek, Mehmet Ali̇ Gündoğdu, Nesri̇n Aktepe Tangu, Sevi̇n Teoman Duran, Murat Şeker, Mustafa Akbulut Aug 2024

Qtl Mapping For Fatty Acid Composition In Olive Oil Using A High-Density Genetic Map Based On Snp Markers, Ali̇ Can Kaya, Meryem İpek, Ahmet İpek, Mehmet Ali̇ Gündoğdu, Nesri̇n Aktepe Tangu, Sevi̇n Teoman Duran, Murat Şeker, Mustafa Akbulut

Turkish Journal of Agriculture and Forestry

Olive (Olea europaea L.) is an evergreen tree species that grows naturally in regions with Mediterranean climates. Its oil and fruits are commercially valuable. Olive oil contains high levels of omega-9 (oleic acid). Because the high percentage of oleic acid makes olive oil deterioration-resistant, the development of olive varieties containing high oleic acid is one of the major goals of olive breeding programs. Therefore, this study aimed to determine quantitative trait loci (QTL) affecting fatty acid composition of olive oil. Thus, early selection of olive genotypes with a high oleic acid content can be possible. For the determination of QTLs …


Legal Regime Of The Application Process For Gmo Products In Türkiye, Ünal Yildiz, Özgür Temi̇z, Kami̇l Hali̇loğlu, Nesri̇n Yildiz Aug 2024

Legal Regime Of The Application Process For Gmo Products In Türkiye, Ünal Yildiz, Özgür Temi̇z, Kami̇l Hali̇loğlu, Nesri̇n Yildiz

Turkish Journal of Agriculture and Forestry

In Turkiye, in accordance with EU harmonization laws, Biosafety Act No. 5977 entered into force on 18.09.2010. The basic legislation regarding the application process is composed of the Biosafety Act, Regulations on Genetically Modified Organisms and Their Products, and Regulations on Working Procedures and Principles of Biosafety Board and Committees. Biosafety legislation foresees a special application procedure for GMO food, food products, feed, and other products. The application regulated in the Biosafety Law is a special administrative procedure in nature. The primary objective of this study is to explain the legal regime of this application procedure. While explaining this issue, …


Quantitative Variation Of Phenolic Compounds In Different Tissues Of Pistachio(Pistacia Vera L. Cv. Uzun) Associated With Alternate Bearing, Müjgan Güney, Muhammet Ali̇ Gündeşli̇, Murat Güney, Nesi̇be Ebru Kafkas, Sali̇h Kafkas, Zeynep Ergün Aug 2024

Quantitative Variation Of Phenolic Compounds In Different Tissues Of Pistachio(Pistacia Vera L. Cv. Uzun) Associated With Alternate Bearing, Müjgan Güney, Muhammet Ali̇ Gündeşli̇, Murat Güney, Nesi̇be Ebru Kafkas, Sali̇h Kafkas, Zeynep Ergün

Turkish Journal of Agriculture and Forestry

Alternate bearing is a common challenge in horticultural plants, leading to irregular yield in successive years. The potentialrole of phenolic compounds in regulating this phenomenon, however, is not well understood. This study aimed to investigate thepotential role of phenolic compounds in alternate bearing in pistachio trees by analysing samples from different parts of the “Uzun”cultivar over two consecutive years. Seven phenolic compounds (gallic acid, p-coumaric acid, caffeic acid, ferulic acid, chlorogenic acid,catechin, and quercetin) were analysed using high-performance liquid chromatography at 10-day intervals. Significant variations wereobserved in the levels of certain phenolic compounds between “ON” and “OFF” years, suggesting a …


Developing Micropropagation Protocol For Black Mulberry (Morus Nigra L.), Merve Özkul, Nevzat Sevgi̇n, Mehmet Özkul, Neelam Prabha Negi, Sadi̇ye Peral Eyduran, Bi̇rsen Yilmaz, Melekşen Akin Aug 2024

Developing Micropropagation Protocol For Black Mulberry (Morus Nigra L.), Merve Özkul, Nevzat Sevgi̇n, Mehmet Özkul, Neelam Prabha Negi, Sadi̇ye Peral Eyduran, Bi̇rsen Yilmaz, Melekşen Akin

Turkish Journal of Agriculture and Forestry

This study aims to develop a suitable micropropagation protocol for black mulberry, which cannot be easily clonally propagated like other mulberry species. Clonal propagation of this species is gaining importance due to its health benefits and utilization in pharmacology. The effects of culture media and cytokinin types on micropropagation of Morus nigra L. were investigated. Single-axillary bud explants grown on MS, DKW, and NRM containing 0.25 mg/l benzyl adenine (BA) plus 0.01 mg/l indole-3-butyric acid (IBA) were compared to cultures grown on NRM with thidiazuron, metaTopolin (mT) or BA at 1.25, 2.5, 5.0 or 7.5 mg/l plus 0.01 mg/l IBA. …


Biostimulation Effect On Crithmum Maritimum L. Root Development In Controlled Environment, Stefano Zenobi, Marco Fiorentini, Biagio Di Tella, Vesna Milanovic, Andera Marcelli, Luigi Ledda, Paola Antonia Deligios, Lucia Aquilanti, Roberto Orsini Aug 2024

Biostimulation Effect On Crithmum Maritimum L. Root Development In Controlled Environment, Stefano Zenobi, Marco Fiorentini, Biagio Di Tella, Vesna Milanovic, Andera Marcelli, Luigi Ledda, Paola Antonia Deligios, Lucia Aquilanti, Roberto Orsini

Turkish Journal of Agriculture and Forestry

Biostimulants can find application in sustainable agriculture contexts as they are regarded as inputs with minimal environmental impact. Microbial inoculants, when applied to the root systems of certain plant species, confer physiological and morphological benefits to the entire plant. In the present study, we focused on some morphometric parameters of the root system of two Crithmum maritimum L. spontaneous populations (Mediterranean and Atlantic). We compared the effects of two different (for number of strains) biostimulants on the weight, length, diameter and number of tips on the root system. The experiment was conducted within two types of controlled environments: i) an …


Characterization And Bioremediation Potential Of Heavy-Metal Resistant Bacteria Isolated From Agricultural Soil, Kheira Dahnoun, Fatima Djadouni, Badiaa Essghaier, Chahnez Naccache, Nadia Zitouna, Salwa Zehdi-Azouzi, İsmai̇l Bayyi̇ği̇t, Hijran Rafiyeva Latif, Maha Mezghani-Khemakhem, Hedia Bourguiba Aug 2024

Characterization And Bioremediation Potential Of Heavy-Metal Resistant Bacteria Isolated From Agricultural Soil, Kheira Dahnoun, Fatima Djadouni, Badiaa Essghaier, Chahnez Naccache, Nadia Zitouna, Salwa Zehdi-Azouzi, İsmai̇l Bayyi̇ği̇t, Hijran Rafiyeva Latif, Maha Mezghani-Khemakhem, Hedia Bourguiba

Turkish Journal of Agriculture and Forestry

Heavy metal pollution is a major environmental issue that has a negative impact on soil quality and food security. As a result, heavy metal removal or remediation from hazardous sites has become mandatory. Bioremediation based on microorganisms is a promising method to remediate heavy metal-contaminated areas due to its eco-friendly, cost-effective, and highly efficient characteristics. This study aimed to isolate, identify and characterize rhizospheric bacteria able to resist, reduce, and detoxify heavy metals (chromium [Cr], nickel [Ni], and aluminum [Al]) from agricultural soil. Two isolates were chosen due to their high level of heavy metal resistance and could serve as …


Evaluation Of Turkish Shallot Genetic Resources For Morphological, Biochemical And Sensory Properties, Gülay Beşi̇rli̇ Aug 2024

Evaluation Of Turkish Shallot Genetic Resources For Morphological, Biochemical And Sensory Properties, Gülay Beşi̇rli̇

Turkish Journal of Agriculture and Forestry

Shallots, a subspecies of onion, are considered the gourmet onion and are preferred especially in French and Asian cooking. Its unique taste and aroma especially being caramelized through heat treatment increases its importance for boutique restaurants and niche tables. This study examined the morphological, biochemical, and sensory properties of seven generatively (GMSY-2, GMSY-3, GMSY-4, GMSY-5, GMSY-6, GMSY-7, GMSY-8) and one vegetatively propagated (GMSY-1) shallot genotypes in 2021 and 2022. Sixteen morphological and fifteen biometric features of UPOV were used in characterization. Total phenolic content, total antioxidant capacity, and total monomeric anthocyanin and pyruvic acid contents were determined as biochemical markers. …


Ensemble Learning For Accurate Prediction Of Heart Sounds Using Gammatonegram Images, Sinam Ashinikumar Singh, Sinam Ajitkumar Singh, Aheibam Dinamani Singh Jul 2024

Ensemble Learning For Accurate Prediction Of Heart Sounds Using Gammatonegram Images, Sinam Ashinikumar Singh, Sinam Ajitkumar Singh, Aheibam Dinamani Singh

Turkish Journal of Electrical Engineering and Computer Sciences

The analysis of heart sound signals constitutes a pivotal domain in healthcare, with the prediction of imbalanced heart sounds offering critical diagnostic insights. However, the inherent diversity in cardiac sound patterns presents a substantial challenge in predicting imbalanced signals. Many scientific disciplines have focused a great deal of emphasis on the problem of class inequality. We introduce an ensemble learning approach employing a convolutional neural network model-based deep learning algorithm to effectively tackle the challenges associated with predicting imbalanced heart sound signals. We use a Gammatone filter bank to extract relevant features from the heard sound signal. Our approach leverages …


Multi-Label Voice Disorder Classification Using Raw Waveforms, Gökay Di̇şken Jul 2024

Multi-Label Voice Disorder Classification Using Raw Waveforms, Gökay Di̇şken

Turkish Journal of Electrical Engineering and Computer Sciences

Automated voice disorder systems that distinguish pathological voices from healthy ones have been developed with the aid of machine learning methods. Both clinicians and patients can benefit from these systems as they provide many advantages, compared to the invasive techniques. These systems can produce binary (healthy/pathological) or multi-class (healthy/selected pathologies) decisions. However, multiple disorders might exist in an individual’s voice. Multi-label classification should be considered in such cases. By this time, only a single report is available on this topic, where hand-crafted features were used, and a data augmentation technique was utilized to overcome class imbalances. In this study, a …


Novelties In Funalia And The Status Of Fomitella (Polyporaceae, Basidiomycota), Virton Rodrigo Targino De Oliveira, Paulo Roberto De Assis Alves, Nelson Correia De Lima-Júnior, Carla Santos, Nelson Lima, Leif Ryvarden, Josef Vlasák, Tatiana Baptista Gibertoni Jul 2024

Novelties In Funalia And The Status Of Fomitella (Polyporaceae, Basidiomycota), Virton Rodrigo Targino De Oliveira, Paulo Roberto De Assis Alves, Nelson Correia De Lima-Júnior, Carla Santos, Nelson Lima, Leif Ryvarden, Josef Vlasák, Tatiana Baptista Gibertoni

Turkish Journal of Botany

During studies on the taxonomical delimitation of some species of Funalia, some inconsistencies were observed in the genus. Based on morphological and phylogenetic analyses, Fomitella supina was positioned within the Funalia clade, thus the synonymization of the genus and the new combination of F. supina are proposed. Funalia glabrorigens is also combinated in the genus, while Coriolopsis hainanensis is suggested as a synonym of F. floccosa and F. rigida is assumed as a distinct species from F. floccosa. A table with morphological comparison of the 10 Funalia species confirmed by molecular analyses is also presented.


Cover And Contents Jul 2024

Cover And Contents

Turkish Journal of Botany

No abstract provided.


Mattiastrum Pulumurense (Cynoglossinae, Boraginaceae), A New Endemic Species From Türkiye, Asli Doğru Koca, Mustafa Gökmen, Gülderen Yilmaz, Mehmet Yavuz Paksoy Jul 2024

Mattiastrum Pulumurense (Cynoglossinae, Boraginaceae), A New Endemic Species From Türkiye, Asli Doğru Koca, Mustafa Gökmen, Gülderen Yilmaz, Mehmet Yavuz Paksoy

Turkish Journal of Botany

A new species, Mattiastrum pulumurense, has been described from Tunceli in eastern Turkey. It is generally distinguished from other species (except M. racemosum var. scabridum) by a sparsely hairy or glabrescent above-ground part. It is most similar morphologically to M. longipes, M. calycinum and Paracaryum hedgei (P. hedgei is potential a member of the genus Mattiastrum). However, it differs from M. longipes and M. calycinum by its 3-3.5 mm long and linear lanceolate scales, 2.5-4.5 mm long anthers, and 10-15 mm long styles; it differs from Paracaryum hedgei by its 3-3.5 mm long scales, 2.5-4.5 mm long anthers. In addition, …


Corrigendum To “Two New Species Of Inocybe (Inocybaceae: Agaricomycetes) From Türkiye Based On Morphological Characteristics And Phylogenetic Evidence [Turkish Journal Of Botany 48 (3) 2024 145-154 ], Oğuzhan Kaygusuz, Ditte Bandini, Henning Knudsen, Meike Piepenbring Jul 2024

Corrigendum To “Two New Species Of Inocybe (Inocybaceae: Agaricomycetes) From Türkiye Based On Morphological Characteristics And Phylogenetic Evidence [Turkish Journal Of Botany 48 (3) 2024 145-154 ], Oğuzhan Kaygusuz, Ditte Bandini, Henning Knudsen, Meike Piepenbring

Turkish Journal of Botany

This corrigendum is to address an issue regarding the manuscript's previous publication, specifically Fig. 5.Regrettably, the authors have noticed that the Figure 5 is missing among the figures although there is an incite reference within the text. To rectify this oversight and ensure the accuracy of the published work, the Figure 5 is included for your reference.

Link to the original article: https://journals.tubitak.gov.tr/botany/vol48/iss3/3/


Cover And Contents Jul 2024

Cover And Contents

Turkish Journal of Zoology

No abstract provided.


Spatial And Temporal Nesting Pattern Of Sea Turtles In Alas Purwo National Park, And Itsimplications For Conservation Management Practices, Nia Kurniawan, Novita Kusuma Wardani, Noviyani Utami, Muhammad Asyraf Rijalullah, Miftah Farid Assiddiqy, Awang Gitayana, Hartono Hartono, Muhammad Fathoni, Andreas Bandang Hardian Jul 2024

Spatial And Temporal Nesting Pattern Of Sea Turtles In Alas Purwo National Park, And Itsimplications For Conservation Management Practices, Nia Kurniawan, Novita Kusuma Wardani, Noviyani Utami, Muhammad Asyraf Rijalullah, Miftah Farid Assiddiqy, Awang Gitayana, Hartono Hartono, Muhammad Fathoni, Andreas Bandang Hardian

Turkish Journal of Zoology

As a sea turtle conservation area, Alas Purwo National Park (APNP) shows different patterns in the four species of turtles thathave nesting records, such as an increase in Olive Ridley Turtle (Lepidochelys olivacea), stability in Green Turtle (Chelonia mydas), anda decline in Hawksbill Turtle (Eretmochelys imbricata) and Leatherback Turtle (Dermochelys coriacea). During the survey, which lastedfrom January to July 2023, we discovered that each type of sea turtle preferred nesting sites at specific hypothetical stations, except forthe L. olivacea, which nested at all hypothetical stations along Pancur-Cungur Coast. We also discovered that it is highly encouragedto continue relocations that have …


Modeling Habitat Suitability And Current Distribution Of The Relicted Maghreb Magpie (Pica Mauritanica), Kamel Eddine Mederbal, Mohcen Menaa, Abdallah Aouadi, Lamia Boutabia, Lamia Bensaâd-Bendjedid, Khalladi Mederbal, Amira Bouderbala, Abderrahmane Chebli, Salah Telailia Jul 2024

Modeling Habitat Suitability And Current Distribution Of The Relicted Maghreb Magpie (Pica Mauritanica), Kamel Eddine Mederbal, Mohcen Menaa, Abdallah Aouadi, Lamia Boutabia, Lamia Bensaâd-Bendjedid, Khalladi Mederbal, Amira Bouderbala, Abderrahmane Chebli, Salah Telailia

Turkish Journal of Zoology

The Maghreb Magpie (Pica mauritanica) is an endemic bird to North Africa, encompassing Algeria, Morocco, and Tunisia. Unfortunately, its population is facing a significant decline primarily attributed to habitat loss and fragmentation resulting from urbanization and agricultural practices. Due to the lack of studies on habitat requirements of Pica mauritanica on a large scale, investigating the habitat preferences of this species and thereby understanding the potential threats, remains crucial for effective conservation strategies. We performed species distribution modeling (SDM), incorporating both occurrence records and predictor variables, to investigate the potentially suitable habitat and the factors influencing the distribution of the …


Limited Thermal Plasticity In High Mountain Tropical Water Bear, Juan Manuel Carvajalino-Fernández, Valentina Diaz-Galvis, Alan Dante Torres-Jaramillo Jul 2024

Limited Thermal Plasticity In High Mountain Tropical Water Bear, Juan Manuel Carvajalino-Fernández, Valentina Diaz-Galvis, Alan Dante Torres-Jaramillo

Turkish Journal of Zoology

Tardigrades, a phylum of microscopic organisms well known for their resistance to extreme conditions thanks to adaptations such as cryptobiosis, in which they are able to suspend their metabolism until more favorable conditions arise. These organisms are found in a wide range of environments, and high Andean mountains are not the exception, even though weather conditions are highly variable during the day, let alone a month. An experiment was thus conducted at 2600m in Bogotá, Colombia to evaluate the resistance of Macrobiotus sp. found on trees, three sets of fifteen tardigrades were exposed to 20 °C, 30 °C and 40 …


Artificial Light At Night On Nesting Beaches Of The Green Turtle, Chelonia Mydas, In The Eastern Mediterranean And Its Possible Effect On Populations, Noam Leader, Yaniv Levy, Oğuz Türkozan Jul 2024

Artificial Light At Night On Nesting Beaches Of The Green Turtle, Chelonia Mydas, In The Eastern Mediterranean And Its Possible Effect On Populations, Noam Leader, Yaniv Levy, Oğuz Türkozan

Turkish Journal of Zoology

Artificial light associated with coastal development is becoming one of the major threats to coastal biodiversity. Sea turtles are coastal breeders, and it is well-known that hatchlings tend to move toward lighter objects on the beach, which prevents them from reaching the sea. It is, therefore, essential to identify the impact of artificial light at night (ALAN) on the nesting beaches. Here, we investigated ALAN levels using imagery from satellites at important green turtle (Chelonia mydas) nesting beaches in the Mediterranean. Mean August radiance levels at nesting beaches ranged from 0.00473 nW/cm2sr (Northern Cyprus-South Karpaz Beach) to 14.44 nW/cm2sr (Turkey …


Identification Of Blood Meals In Field Collected Culex Pipiens, Anopheles Sacharovi And Culex Tritaeniorhynchus (Diptera: Culicidae) Using The Elisa Method, Fatma Bursali, Gi̇zem Anti̇ka, Sare İlknur Yavaşoğlu, Fati̇h Mehmet Şi̇mşek Jul 2024

Identification Of Blood Meals In Field Collected Culex Pipiens, Anopheles Sacharovi And Culex Tritaeniorhynchus (Diptera: Culicidae) Using The Elisa Method, Fatma Bursali, Gi̇zem Anti̇ka, Sare İlknur Yavaşoğlu, Fati̇h Mehmet Şi̇mşek

Turkish Journal of Zoology

Information obtained about the blood feeding behavior of mosquito populations in nature is important for understanding their vectorial capacity and evaluating their potential role in the transmission of vector-borne diseases. This study investigated the feeding patterns of Culex pipiens, Anopheles sacharovi and Culex tritaeniorhynchus by using ELISA method. A total of 435 blood-fed females were collected from the Aegean and Mediterranean regions of Türkiye between May 2021-September 2023. The types and numbers of potential domestic animal hosts were recorded in each village. Of the 372 blood meals tested, 348 gave a single host positive result mainly on bovine and human, …


Cover And Contents Jun 2024

Cover And Contents

Turkish Journal of Biology

No abstract provided.


O-Demethyl Galantamine Alters Protein Expression In Cerebellum Of 5xfad Mice, İrem Kiriş, Merve Karayel Başar, Büşra Gurel, Tomasz Mroczek, Ahmet Tarik Baykal Jun 2024

O-Demethyl Galantamine Alters Protein Expression In Cerebellum Of 5xfad Mice, İrem Kiriş, Merve Karayel Başar, Büşra Gurel, Tomasz Mroczek, Ahmet Tarik Baykal

Turkish Journal of Biology

Background/aim: Alzheimer’s disease (AD), one of the most common health issues, is characterized by memory loss, severe behavioral disorders, and eventually death. Despite many studies, there are still no drugs that can treat AD or stop it from progressing. Previous in vitro tests showed that O-demethyl galantamine (ODG) might have a therapeutic potential owing to its 10 times higher acetylcholinesterase inhibitory activity than galantamine (GAL). Materials and methods: We aimed to assess effect of ODG on a molecular level 12-month-old 5xFAD Alzheimer’s mouse model. To this end, following the administrations of ODG and GAL, used as a positive control, protein …


Petox-Dope Nanoliposomes Functionalized With Peptide 563 In Targeted Bikdda Delivery To Prostate Cancer, Ayca Ece Nezi̇r, Zeynep Büşra Bolat, Ongun Mehmet Saka, Itir Ebru Zemheri̇, Sevgi̇ Gülyüz, Umut Uğur Özköse, Özgür Yilmaz, Asuman Bozkir, Fi̇kretti̇n Şahi̇n, Di̇lek Telci̇ Jun 2024

Petox-Dope Nanoliposomes Functionalized With Peptide 563 In Targeted Bikdda Delivery To Prostate Cancer, Ayca Ece Nezi̇r, Zeynep Büşra Bolat, Ongun Mehmet Saka, Itir Ebru Zemheri̇, Sevgi̇ Gülyüz, Umut Uğur Özköse, Özgür Yilmaz, Asuman Bozkir, Fi̇kretti̇n Şahi̇n, Di̇lek Telci̇

Turkish Journal of Biology

BackgroundNanocarrier-based systems have cultivated significant improvements in prostate cancer therapy. However, the efforts are still limited in clinical applicability, and more research is required for the development of effective strategies. Here, we describe a novel nanoliposomal system for targeted apoptotic gene delivery to prostate cancer.MethodsPoly (2-ethyl-2-oxazoline) (PEtOx) dioleoyl phosphatidylethanolamine (DOPE) nanoliposomes were conjugated with the prostate-specific membrane antigen (PSMA)-targeting peptide GRFLTGGTGRLLRIS (P563) and loaded with BikDDA, a mutant form of the proapoptotik Bik. We selected 22Rv1 cells with moderate upregulation of PSMA to test the in vitro uptake, cell death, and in vivo anti-cancer activity of our formulation, P563-PEtOx-DOPE-BikDDA.ResultsBikDDA was …


The Apoptotic Effect Of Garlic (Allium Sativum) Derived Sevs On Different Types Of Cancer Cell Lines In Vitro, Naz Ünsal, Polen Koçak Deni̇zci̇, Hazal Yilmaz, Fi̇kretti̇n Şahi̇n, Merve Yildirim Canpolat Jun 2024

The Apoptotic Effect Of Garlic (Allium Sativum) Derived Sevs On Different Types Of Cancer Cell Lines In Vitro, Naz Ünsal, Polen Koçak Deni̇zci̇, Hazal Yilmaz, Fi̇kretti̇n Şahi̇n, Merve Yildirim Canpolat

Turkish Journal of Biology

Small extracellular vesicles (SEVs) are known to have an impact on the physiological circumstances of the target cells, are a critical component of cell-to-cell communication and have been implicated in a variety of diseases. Although it has been proposed that edible plant-derived nanoparticles have effect on communication with mammalian cells, the influence of these nanoparticles on cancer cell development has yet to be explored. In order to characterize small extracellular vesicles obtained from garlic, specific SEV surface markers and antibodies and size detections were performed by using scanning electron microscopy and nanoparticle tracking analysis. Human hepatoma, Hep3B, human neuroblastoma SH-SY5Y, …


Proteomic Investigation Of Acute And Chronic Hypoxia /Reoxygenation Responsive Proteins And Pathways In H9c2 Cardiomyoblasts, Merve Öztuğ, Evren Kilinç, Zeynep A. Öztuğ Durer, Emel Baloğlu Jun 2024

Proteomic Investigation Of Acute And Chronic Hypoxia /Reoxygenation Responsive Proteins And Pathways In H9c2 Cardiomyoblasts, Merve Öztuğ, Evren Kilinç, Zeynep A. Öztuğ Durer, Emel Baloğlu

Turkish Journal of Biology

Background/Aim: Ischemic heart diseases continue to be a significant global cardiovascular problem in today's world. Myocardial reperfusion (R) is provided with an effective and rapid treatment; however, it can lead to fatal results as well as ischemia (I). This study aims to use proteomic analysis to assess proteins and pathways in H9C2 cardiomyoblast cells exposed to hypoxic conditions, followed by reoxygenation, representing I /R injury for both short and long terms, reflecting acute and chronic hypoxia, respectively. Utilizing advanced techniques, our goal is to identify and characterize key proteins undergoing alterations during these critical phases.Materials and methods: H9C2 cardiomyoblasts, commonly …


Lungbank: A Novel Biorepository Strategy Tailored For Comprehensive Multi-Omics Analysis And P-Medicine Applications In Lung Cancer, Di̇lek Demi̇rcan Çeker, Volkan Baysungur, Serdar Evman, İlker Kolbaş, Abdurrahi̇m Gördebi̇l, Si̇nem M. Nalbantoğlu, Yusuf Tambağ, Ömer Kaçar, Ahmet Mi̇di̇, Hati̇ce Aslanoğlu, Nülüfer Kara, Ni̇lgün Algan, Ayberk Boyacioğlu, Betül Karademi̇r Yilmaz, Ali̇ Şahi̇n, Hi̇vda Ülbeği̇ Polat, Abi̇di̇n Şehi̇toğullari, Ali̇ Osman Çibikdi̇ken, Mücahi̇t Büyükyilmaz, İbrahi̇m Berkan Aydi̇lek, Abdulkeri̇m Eneş, Sevde Küçüker, Fati̇h Karakaya, İhsan Boyaci, Mahmut Gümüş, Onur Şenol, Merve Öztuğ, Evren Saban, Ömer Soysal, Nur Büyükpinarbaşili, Akif Turna, Mehmet Zeki Günlüoğlu, Aslı Çakir, Şaban Teki̇n, Uygar Tazebay, Abdullah Karadağ Jun 2024

Lungbank: A Novel Biorepository Strategy Tailored For Comprehensive Multi-Omics Analysis And P-Medicine Applications In Lung Cancer, Di̇lek Demi̇rcan Çeker, Volkan Baysungur, Serdar Evman, İlker Kolbaş, Abdurrahi̇m Gördebi̇l, Si̇nem M. Nalbantoğlu, Yusuf Tambağ, Ömer Kaçar, Ahmet Mi̇di̇, Hati̇ce Aslanoğlu, Nülüfer Kara, Ni̇lgün Algan, Ayberk Boyacioğlu, Betül Karademi̇r Yilmaz, Ali̇ Şahi̇n, Hi̇vda Ülbeği̇ Polat, Abi̇di̇n Şehi̇toğullari, Ali̇ Osman Çibikdi̇ken, Mücahi̇t Büyükyilmaz, İbrahi̇m Berkan Aydi̇lek, Abdulkeri̇m Eneş, Sevde Küçüker, Fati̇h Karakaya, İhsan Boyaci, Mahmut Gümüş, Onur Şenol, Merve Öztuğ, Evren Saban, Ömer Soysal, Nur Büyükpinarbaşili, Akif Turna, Mehmet Zeki Günlüoğlu, Aslı Çakir, Şaban Teki̇n, Uygar Tazebay, Abdullah Karadağ

Turkish Journal of Biology

Background/aim: LUNGBANK was established as a pioneering biorepository dedicated to lung cancer. Designed for streamlined biospecimens handling, it employs high-volume technologies to secure high-quality samples. Fortified with robust data management, LUNGBANK efficiently integrates diverse datasets. This strategic infrastructure positions LUNGBANK as more than a biospecimens repository; it operates as a sophisticated platform for advanced lung cancer research, amplifying the potential for meaningful discoveries.Materials and methods: LUNGBANK is intricately designed to streamline the collection, transfer, storage, and processing of biospecimens, employing high-volume technologies to ensure the acquisition of high-quality biological specimens. The system is fortified with robust data management protocols, facilitating …


Senggani Fruit (Melastoma Malabathricum Linn.) Extract As A Natural Indicator In Ph-Responsive Pva-Taro Starch Plastic Packaging, Rika Risma Dewi, Intan Syahbanu, Winda Rahmalia Jun 2024

Senggani Fruit (Melastoma Malabathricum Linn.) Extract As A Natural Indicator In Ph-Responsive Pva-Taro Starch Plastic Packaging, Rika Risma Dewi, Intan Syahbanu, Winda Rahmalia

Turkish Journal of Chemistry

Polyvinyl alcohol (PVA)-starch-based bioplastics are widely used in many applications. pH-responsive plastic packaging was produced through the incorporation of senggani (Melastoma malabathricum Linn.) fruit extract into PVA-taro starch-based plastic packaging. The objective of this research was to examine the characteristics of senggani fruit extract under different pH conditions and explore its application as a pH indicator in intelligent packaging. The senggani fruit was extracted through the maceration method using a solvent comprising 96% ethanol and 3% citric acid, with a ratio of 85:15 (v/v). The senggani fruit extract solution underwent color changes, appearing pink at pH levels below 6, pale …


Dft Modeling Of Water-Assisted Hydrogen Peroxide Formation From A C(4a)-(Hydro)Peroxyflavin, Yilmaz Özkiliç Jun 2024

Dft Modeling Of Water-Assisted Hydrogen Peroxide Formation From A C(4a)-(Hydro)Peroxyflavin, Yilmaz Özkiliç

Turkish Journal of Chemistry

The cofactor of a class A monooxygenase is reduced at an external location of the enzyme and is subsequently pulled back into the active site after the reduction. This observation brings the question; is there any defense mechanism of the active site of a monooxygenase against the formation of the harmful hydrogen peroxide from the reactive C(4a)-(hydro)peroxide intermediate? In this study, the barrier energies of one to three water molecule-mediated uncoupling reaction mechanisms in water exposed reaction conditions were determined. These were found to be facile barriers. Secondly, uncoupling was modeled in the active site of kynurenine 3-monooxygenase complex which …


Effect Of Quince Seed Gum (Qsg) On The Performance Of Injectable Hyaluronic Acid Hydrogels In Terms Of The Rheological, Morphological, And Mechanical Aspect, Serdar Kolay, Ni̇lhan Kayaman Apohan, Erdi̇nç Babuç, Gökay Gün Jun 2024

Effect Of Quince Seed Gum (Qsg) On The Performance Of Injectable Hyaluronic Acid Hydrogels In Terms Of The Rheological, Morphological, And Mechanical Aspect, Serdar Kolay, Ni̇lhan Kayaman Apohan, Erdi̇nç Babuç, Gökay Gün

Turkish Journal of Chemistry

Injectable hydrogels play an important role in tissue engineering as a filling and repairing material. This study aimed to develop a new injectable hydrogel based on hyaluronic acid (HA) and quince seed gum (QSG) and investigate the effect of QSG on hydrogel performance. The amount of unreacted 1,4-Butanediol diglycidyl ether (BDDE) is maintained at an undetectable level for HA-QSG hydrogels. Amino acid analysis showed that the HA-QSG hydrogel had rich amino acid concentrations of leucine, arginine, and valine. After thermal sterilization, the elastic modulus of HA-QSG gels for dermal and intra-articular filler applications is 63 Pa and 92 Pa respectively. …