Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Life Sciences (5932)
- Medicine and Health Sciences (2313)
- Animal Sciences (2151)
- Physical Sciences and Mathematics (1962)
- Biology (1669)
-
- Medical Sciences (1464)
- Zoology (1302)
- Chemistry (1183)
- Botany (1118)
- Plant Sciences (1118)
- Agriculture (994)
- Forest Sciences (994)
- Veterinary Medicine (849)
- Computer Engineering (461)
- Computer Sciences (461)
- Electrical and Computer Engineering (461)
- Engineering (461)
- Mathematics (146)
- Earth Sciences (107)
- Physics (65)
- Keyword
-
- Turkey (609)
- Taxonomy (221)
- Oxidative stress (132)
- New records (121)
- New species (104)
-
- Apoptosis (93)
- Morphology (93)
- New record (91)
- Antioxidant (83)
- Distribution (80)
- Phylogeny (79)
- COVID-19 (78)
- Cytotoxicity (73)
- Growth (73)
- Biodiversity (72)
- Antimicrobial activity (71)
- Iran (71)
- 1 (67)
- Inflammation (66)
- 2 (63)
- Breast cancer (62)
- Fauna (61)
- Rat (61)
- Antioxidant activity (60)
- Genetic diversity (60)
- Gene expression (59)
- Antioxidant enzymes (48)
- Endemic (48)
- Antibacterial activity (47)
- Cancer (47)
- Publication Year
Articles 3901 - 3930 of 10521
Full-Text Articles in Entire DC Network
Structure Of Molluscan Communities In Shallow Subtidal Rocky Bottoms Of Acapulco, Mexico, José Gabriel Kuk Dzul, Jesús Guadalupe Padilla Serrato, Carmina Torreblanca Ramirez, Rafael Flores Garza, Pedro Flores Rodríguez, Ximena Itzamara Muñiz Sánchez
Structure Of Molluscan Communities In Shallow Subtidal Rocky Bottoms Of Acapulco, Mexico, José Gabriel Kuk Dzul, Jesús Guadalupe Padilla Serrato, Carmina Torreblanca Ramirez, Rafael Flores Garza, Pedro Flores Rodríguez, Ximena Itzamara Muñiz Sánchez
Turkish Journal of Zoology
The objective of this study was to determine the structure of molluscan communities in shallow subtidal rocky bottoms of Acapulco, Mexico. Thirteen samplings were performed at 8 stations in 2012 (seven samplings), 2014 (four), and 2015 (two). The collection of the mollusks in each station was done at a maximum depth of 5 m for 1 h by 3 divers. A total of 2086 specimens belonging to 89 species, 36 families, and 3 classes of mollusks were identified. Gastropoda was the most diverse and abundant group. Calyptreaidae, Columbellidae, and Muricidae had >5 species, but Pisaniidae, Conidae, Fasciolariidae, and Muricidae had …
Detailed Analysis Of Beluga Sturgeon (Huso Huso) And Stellate Sturgeon(Acipenser Stellatus) Migration In The Lower Danube River, Stefan Hont, Marian Paraschiv, Marian Ion Iani, Elena Taflan, Daniela Nicoleta Holostenco, Delia Oprea, Lucian Oprea
Detailed Analysis Of Beluga Sturgeon (Huso Huso) And Stellate Sturgeon(Acipenser Stellatus) Migration In The Lower Danube River, Stefan Hont, Marian Paraschiv, Marian Ion Iani, Elena Taflan, Daniela Nicoleta Holostenco, Delia Oprea, Lucian Oprea
Turkish Journal of Zoology
The swimming ground speed and swimming depths of beluga sturgeon (Huso huso) and stellate sturgeon (Acipenser stellatus) were investigated using ultrasonic telemetry between 2011 and 2017 in the Lower Danube River (river kilometer (rkm) 0 Sulina-rkm 1075 Baziaş). Acoustic telemetry receivers VR2W and V16TP tags (Vemco, Canada) were used to collect data about sturgeon migration behavior in the Lower Danube River between the Black Sea and the Iron Gate II dam. The tags, equipped with depth and temperature sensors, provided data about beluga and stellate sturgeon migration periods, swimming speeds, and depths. Twenty-three beluga sturgeon (184-245 cm TL) and twenty-one …
Comparative Evaluation Of Taxonomic And Functional Diversities Of Leaf-Litter Ants Of The Brazilian Atlantic Forest, Elmo Borges De Azevedo Koch, José Raimundo Maia Dos Santos, Ivan Cardoso Nascimento, Jacques Hubert Charles Delabie
Comparative Evaluation Of Taxonomic And Functional Diversities Of Leaf-Litter Ants Of The Brazilian Atlantic Forest, Elmo Borges De Azevedo Koch, José Raimundo Maia Dos Santos, Ivan Cardoso Nascimento, Jacques Hubert Charles Delabie
Turkish Journal of Zoology
The ant community living in leaf litter was assessed in 65 forest sites in the Brazilian Atlantic rainforest in the southern region of the state of Bahia, Brazil. In addition, we aimed to understand the patterns between taxonomic and functional diversities using two different resolutions of classification of ants into functional groups. We identified 364 ant species belonging to 68 genera in 10 subfamilies in 65 regions. Considering a more general functional classification, we identified a total of 13 functional ant groups, and 26 functional ant groups considering a more specific functional classification. The Atlantic Forest environments studied presented great …
Spatial Distribution Of The Epigeic Species Of Earthworms Dendrobaena Octaedra And D. Attemsi (Oligochaeta: Lumbricidae) In The Forest Belt Of The Northwestern Caucasus, Anna Geraskina, Nicolai Shevchenko
Spatial Distribution Of The Epigeic Species Of Earthworms Dendrobaena Octaedra And D. Attemsi (Oligochaeta: Lumbricidae) In The Forest Belt Of The Northwestern Caucasus, Anna Geraskina, Nicolai Shevchenko
Turkish Journal of Zoology
Evaluation of the spatial distribution of 2 ecologically similar, but different, in terms of their spatial ranges, earthworm species, D. octaedra and D. attemsi, in the belt forests of northwestern Caucasus were based on our own natural data and using geographic information system (GIS) modeling of modern potential distributions. The quantitative records of earthworms were collected in beech, deciduous, dark coniferous, coniferous-deciduous, and pine forests (1028 geographic locations). Of the most important microsites inhabited by the epigeic earthworms, 2 (plant litter and deadwood) were examined. It was demonstrated that there was high correlation of the 2 species with the humidity …
Spatiotemporal Patterns Of Ground Beetle Diversity (Coleoptera: Carabidae) In A Ramsar Wetland (Chott Tinsilt) Of Algeria, Cherine Amri, Souad Neffar, Nadia Ouchtati, Haroun Chenchouni
Spatiotemporal Patterns Of Ground Beetle Diversity (Coleoptera: Carabidae) In A Ramsar Wetland (Chott Tinsilt) Of Algeria, Cherine Amri, Souad Neffar, Nadia Ouchtati, Haroun Chenchouni
Turkish Journal of Zoology
The aim of this study was to investigate the biodiversity and structure of the Carabidae community living at the edges of a Ramsar wetland in northeastern Algeria, as well as to analyze the effect of environmental variables on this Carabidae community. The study site included two stations (T1, T2). From November 2016 to October 2017, the carabidofauna was sampled fortnightly using pitfall traps. The structure and diversity of the beetle community were measured using nonparametric indices, i.e. species richness, diversity indices, accumulation curves, and similarity analysis. Generalized linear mixed effects models (GLMM) were applied to examine the spatiotemporal variation of …
Molecular Identification Of Invasive Drosophilid Zaprionus Tuberculatus Malloch (Diptera: Drosophilidae) In Çanakkale, Turkey, Akin Kuyulu, Seda Yücel, Hani̇fe Genç
Molecular Identification Of Invasive Drosophilid Zaprionus Tuberculatus Malloch (Diptera: Drosophilidae) In Çanakkale, Turkey, Akin Kuyulu, Seda Yücel, Hani̇fe Genç
Turkish Journal of Zoology
The vinegar or pomace fly, Zaprionus tuberculatus Malloch, is native to the Afrotropical region but has recently colonized new areas in Turkey, Italy, Malta, Romania, and Greece. This invasive species was first detected in 2012 in Adana on banana and peach baits and is considered a potential agricultural pest in fig production in Turkey. However, the European and Mediterranean Plant Organization reports that no direct association of the fly with fruit damage has been documented so far because specimens were generally caught in traps. Specimens of Zaprionus sp. were monitored during surveys for cases of Drosophila suzukii (Matsumura) and Ceratitis …
Modulation Of Pten By Hexarelin Attenuates Coronary Artery Ligation-Induced Heart Failure In Rats, Elvis Agbo, Donghai Liu, Meixiu Li, Roland Osei Saahene, Liqiang Chen, Junpeng Zhao, Yiquan Wang, Guozhong Tian
Modulation Of Pten By Hexarelin Attenuates Coronary Artery Ligation-Induced Heart Failure In Rats, Elvis Agbo, Donghai Liu, Meixiu Li, Roland Osei Saahene, Liqiang Chen, Junpeng Zhao, Yiquan Wang, Guozhong Tian
Turkish Journal of Medical Sciences
Background/aim: Hexarelin is a synthetic growth hormone-releasing peptide that exerts cardioprotective effects. However, its cardioprotective effect against heart failure (HF) is yet to be explained. This study investigated the therapeutic role of hexarelin and the mechanisms underlying its cardioprotective effects against coronary artery ligation (CAL)-induced HF in rats. Materials and methods: Rats with four weeks of permanent CAL, induced myocardial infarction, and HF were randomly separated into four groups: the control group (Ctrl), sham group (Sham), hexarelin treatment group (HF + Hx), and heart failure group (HF). The rats were treated with subcutaneous injection of hexarelin (100 μg/kg) in the …
Childhood Atopic Dermatitis: Current Developments, Treatment Approaches, And Future Expectations, Pinar Gür Çeti̇nkaya, Ümi̇t Murat Şahi̇ner
Childhood Atopic Dermatitis: Current Developments, Treatment Approaches, And Future Expectations, Pinar Gür Çeti̇nkaya, Ümi̇t Murat Şahi̇ner
Turkish Journal of Medical Sciences
Atopic dermatitis (AD) is the most common chronic inflammatory skin disorder of childhood. Underlying factors that contribute to AD are impaired epithelial barrier, alterations in the lipid composition of the skin, immunological imbalance including increased Th2/Th1 ratio, proinflammatory cytokines, decreased T regulatory cells, genetic mutations, and epigenetic alterations. Atopic dermatitis is a multifactorial disease with a particularly complicated pathophysiology. Discoveries to date may be considered the tip of the iceberg, and the increasing number of studies in this field indicate that there are many points to be elucidated in AD pathophysiology. In this review, we aimed to illustrate the current …
The Association Between Levels Of Inflammatory Markers In Autistic Children Compared To Their Unaffected Siblings And Unrelated Healthy Controls, Loai Alzghoul, Sultan Abdelhamid, Ahmad Yanis, Yasmeen Qwaider, Mohammad Aldahabi, Suzan Albdour
The Association Between Levels Of Inflammatory Markers In Autistic Children Compared To Their Unaffected Siblings And Unrelated Healthy Controls, Loai Alzghoul, Sultan Abdelhamid, Ahmad Yanis, Yasmeen Qwaider, Mohammad Aldahabi, Suzan Albdour
Turkish Journal of Medical Sciences
Background/aim: Autism spectrum disorder (ASD) describes a range of neurodevelopmental disabilities that impair behavior and communication. Although it is relatively prevalent, the pathophysiology is still subject to speculation and debate. The aim of this study is to identify a possible association between interleukin-6, -8, -9, and -10 and tumor necrosis factor alpha (TNF- ∝) in autism among Jordanian children by comparing the plasma levels of these cytokines in autistic children with those of their unaffected siblings and unrelated healthy controls. Materials andmethods: In this study, 80 Jordanian children under the age of 12 with diagnosed autism were selected. For comparison, …
Mitoxantrone-Melphalan Conditioning Regimen For Autologous Stem Cell Transplantation In Relapsed/Refractory Lymphoma, Müfi̇de Okay, Yahya Büyükaşik, Haluk Demi̇roğlu, Ümi̇t Yavuz Malkan, Rafi̇ye Çi̇ftçi̇ler, Eli̇fcan Aladağ Karakulak, Sali̇h Aksu, İbrahi̇m Celaletti̇n Haznedaroğlu, Ni̇lgün Sayinalp, Osman İlhami̇ Özcebe, Hakan Göker
Mitoxantrone-Melphalan Conditioning Regimen For Autologous Stem Cell Transplantation In Relapsed/Refractory Lymphoma, Müfi̇de Okay, Yahya Büyükaşik, Haluk Demi̇roğlu, Ümi̇t Yavuz Malkan, Rafi̇ye Çi̇ftçi̇ler, Eli̇fcan Aladağ Karakulak, Sali̇h Aksu, İbrahi̇m Celaletti̇n Haznedaroğlu, Ni̇lgün Sayinalp, Osman İlhami̇ Özcebe, Hakan Göker
Turkish Journal of Medical Sciences
Background/aim: High-dose chemotherapy followed by autologous stem cell transplantation (ASCT) has become the standard approach for patients with relapsed/refractory Hodgkin's lymphoma (HL) or non-Hodgkin's lymphoma (NHL). In this study, we report the outcome of the mitoxantrone-melphalan conditioning regimen for lymphoma. Materials and methods: The study group included 53 patients who were relapsed/refractory HL (n = 14) and NHL (n = 39) and received mitoxantrone and melphalan followed by ASCT. The transplant regimen consisted of mitoxantrone (60 mg/m2) and melphalan (180 mg/m2) followed by peripheral blood stem cell infusion (PBSC). Results: Prior to high-dose chemotherapy, 37.7% of the patients were in …
Efficiency Of Pulsed Electromagnetic Fields On Pain, Disability, Anxiety, Depression, And Quality Of Life In Patients With Cervical Disc Herniation: A Randomized Controlled Study, Erkam Hattapoğlu, İbrahi̇m Batmaz, Banu Di̇lek, Mehmet Karakoç, Serda Em, Remzi̇ Çevi̇k
Efficiency Of Pulsed Electromagnetic Fields On Pain, Disability, Anxiety, Depression, And Quality Of Life In Patients With Cervical Disc Herniation: A Randomized Controlled Study, Erkam Hattapoğlu, İbrahi̇m Batmaz, Banu Di̇lek, Mehmet Karakoç, Serda Em, Remzi̇ Çevi̇k
Turkish Journal of Medical Sciences
Background/aim: In this study, it was aimed to investigate the effects ofpulsed electromagnetic field(PEMF) therapy on pain, disability, psychological state, and quality of life in cervical disc herniation.Materials and methods: Patients were randomly divided into two groups, including Group 1, which received a therapy consisting of transcutaneous electrical nerve stimulation (TENS), hot pack (HP), and PEMF, and Group 2, which received a magnetic field (sham magnetic field) without current flow in addition to TENS and HP therapy. Pain was assessed by a visual analog scale (VAS, 0?10 cm). The other outcome measures were function (Neck Pain and Disability Scale), anxiety-depressive …
Determination Of Insulin Resistance And Its Relationship With Hyperandrogenemia,Anti-Müllerian Hormone, Inhibin A, Inhibin B, And Insulin-Like Peptide-3 Levels In Adolescent Girls With Polycystic Ovary Syndrome, Ayli̇n Yeti̇m Şahi̇n, Fi̇rdevs Baş, Çağcil Yeti̇m, Ahmet Uçar, Şükran Poyrazoğlu, Rüveyde Bundak, Fatma Feyza Darendeli̇ler
Determination Of Insulin Resistance And Its Relationship With Hyperandrogenemia,Anti-Müllerian Hormone, Inhibin A, Inhibin B, And Insulin-Like Peptide-3 Levels In Adolescent Girls With Polycystic Ovary Syndrome, Ayli̇n Yeti̇m Şahi̇n, Fi̇rdevs Baş, Çağcil Yeti̇m, Ahmet Uçar, Şükran Poyrazoğlu, Rüveyde Bundak, Fatma Feyza Darendeli̇ler
Turkish Journal of Medical Sciences
Background/aim: This study aims to investigate the association between polycystic ovary syndrome (PCOS) and obesity and insulin resistance (IR) with respect to anti-Müllerian hormone (AMH), inhibin A (INH-A), inhibin B (INH-B), and insulin-like peptide 3 (INSL3) levels, all factors which may have an impact on IR.Materials and methods: In this cross sectional study, 52 adolescent girls diagnosed with PCOS[groups:nonobese (NO), n = 23; overweight/obese (OW/O), n = 29] were included. Blood samples were obtained to measure AMH, INH-B, INH-A, and INSL3 levels, together with hormonal and biochemical assessments. Oral glucose tolerance test (OGTT) was performed and the indexes of IR …
Investigation Of Oxidant And Antioxidant Levels In Patients With Psoriasis, Okan Kizilyel, Necmetti̇n Akdeni̇z, Mahmut Sami̇ Meti̇n
Investigation Of Oxidant And Antioxidant Levels In Patients With Psoriasis, Okan Kizilyel, Necmetti̇n Akdeni̇z, Mahmut Sami̇ Meti̇n
Turkish Journal of Medical Sciences
Background/aim: Psoriasis is an immune-mediated chronic inflammatory skin disease that is seen in 1%?3% of the population. It is characterized by symmetrical papulosquamous lesions on the scalp, knees, elbows, sacral region, and extensor surfaces of the extremities. Psoriasis affects both sexes equally. It is thought that reactive oxygen species have an important role in inflammatory skin diseases, especially in psoriasis. There are few studies investigating serum oxidant-antioxidant levels in psoriasis. In this study, we aimed to investigate serum oxidant and antioxidant levels in psoriasis and their effects on its pathogenesis. Materials and methods: Included in this study were 50 patients …
Treatment Results In Patients With Ductal Carcinoma In Situ Treated With Adjuvant Radiotherapy, Zeli̇ha Güzelöz Çapar, Lütfi̇ye Zümre Arican Alicikuş, Nesri̇n Aktürk, Meri̇h Güray Durak, Ali̇ İbrahi̇m Sevi̇nç, Pinar Balci, İlknur Görken
Treatment Results In Patients With Ductal Carcinoma In Situ Treated With Adjuvant Radiotherapy, Zeli̇ha Güzelöz Çapar, Lütfi̇ye Zümre Arican Alicikuş, Nesri̇n Aktürk, Meri̇h Güray Durak, Ali̇ İbrahi̇m Sevi̇nç, Pinar Balci, İlknur Görken
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to evaluate the treatment results of patients undergoing adjuvant radiotherapy (ART) after breast surgery with the diagnosis of ductal carcinoma in situ (DCIS).Materials and methods: A total of 61 women who had undergone radiotherapy following extensive surgical excision were enrolled. All patients underwent 50 Gy ART. Survival analysis was performed using Kaplan?Meier analysis and SPSS 20.0.Results: The median age was 52 years (range: 28?86). The median follow-up period after RT was 92 months (range: 23?237). The median overall survival and distant and regional recurrence-free and disease-specific survival was 96 months (range: 26?240), while …
Additional Effects Of Erythropoietin Pretreatment, Ischemic Preconditioning, And N-Acetylcysteine Posttreatment In Rat Kidney Reperfusion Injury, Mohammed Elshiekh, Mehri Kadkhodaee, Behjat Seifi, Mina Ranjbaran
Additional Effects Of Erythropoietin Pretreatment, Ischemic Preconditioning, And N-Acetylcysteine Posttreatment In Rat Kidney Reperfusion Injury, Mohammed Elshiekh, Mehri Kadkhodaee, Behjat Seifi, Mina Ranjbaran
Turkish Journal of Medical Sciences
Background/aim: Since the nature of ischemia/reperfusion (IR)-induced tissue damage is multifactorial and complex, in the current study, the effects of multiple treatment strategies via concomitant administration of erythropoietin (EPO) and N-acetylcysteine (NAC) with an ischemic preconditioning (IPC) regimen on renal IR injury were examined.Materials and methods: Thirty male Wistar rats were subjected to bilateral occlusion of the renal pedicles for 50 min followed by reperfusion. EPO (1000 IU/kg) was administered for 3 days, as well as IPC before the IR and NAC (150 mg/kg) administration for 4 days after IR. The animals were randomly allocated into 6 groups (n = …
Profiling Of 17 Y-Str Loci In Mazandaran And Gilan Provinces Of Iran, Minoo Sayyari, Ali Salehzadeh, Mohamad Amin Tabatabaiefar, Ali Abbasi
Profiling Of 17 Y-Str Loci In Mazandaran And Gilan Provinces Of Iran, Minoo Sayyari, Ali Salehzadeh, Mohamad Amin Tabatabaiefar, Ali Abbasi
Turkish Journal of Medical Sciences
Background/aim: TheY-chromosome mainly consists of heterochromatin regions that have a father-to-son inheritance. Short tandem repeat polymorphic (STRP) markers distributed all over the chromosome provide the opportunity for investigations in forensic medicine and ancestral lineage studies. Due to the existence of wide varieties of geographical and ethnic groups in Iran, studying Y-STRP markers is necessary for further applications. Here we investigated the provinces of Mazandaran and Gilan for the first time. Materials and methods: Samples included 119 and 90 unrelated males from Mazandaran and Gilan, respectively. Using a PCR amplification kit, 17 Y-STRP markers were amplified and genotyping was conducted by …
Capillaroscopic Findings In Turkish Takayasu Arteritis Patients, Ali̇ Akdoğan, Abdulsamet Erden, Esra Firat Şentürk, Levent Kiliç, Alper Sari, Berkan Armağan, Ömer Karadağ, Sedat Ki̇raz
Capillaroscopic Findings In Turkish Takayasu Arteritis Patients, Ali̇ Akdoğan, Abdulsamet Erden, Esra Firat Şentürk, Levent Kiliç, Alper Sari, Berkan Armağan, Ömer Karadağ, Sedat Ki̇raz
Turkish Journal of Medical Sciences
Background/aim: Abnormal capillaroscopic findings have been reported in vasculitic syndromes such as Behçet's disease, Henoch-Schönlein purpura, and Wegener's granulomatosis. This study was conducted to define the capillaroscopic changes in patients with Takayasu arteritis (TA). Materials and methods: We studied 28 TA patients (27 females). The nail folds from the 2nd to 5th fingers on both hands were examined with video capillaroscopy for all. A patient was defined as having an abnormal capillaroscopic examination if more than 1 morphologic abnormality was present in at least 2 nail folds. Results: The median capillary density of TA patients was 9 (range: 9-11). There …
The Combination Of Fatty Liver And Increased Gamma-Glutamyl Transpeptidase Levels As A Risk Factor For Atherosclerotic Plaque Development In Apparently Healthy People, Kaori Kinoshita, Nobuyuki Toshikuni, Takashi Saito, Nobuhiko Hayashi, Takahiro Minato, Yasuhiro Matsue, Yoshimichi Ueda, Mutsumi Tsuchishima, Mikihiro Tsutsumi
The Combination Of Fatty Liver And Increased Gamma-Glutamyl Transpeptidase Levels As A Risk Factor For Atherosclerotic Plaque Development In Apparently Healthy People, Kaori Kinoshita, Nobuyuki Toshikuni, Takashi Saito, Nobuhiko Hayashi, Takahiro Minato, Yasuhiro Matsue, Yoshimichi Ueda, Mutsumi Tsuchishima, Mikihiro Tsutsumi
Turkish Journal of Medical Sciences
Background/aim: To elucidate how the combination of fatty liver and increased serum gamma-glutamyl transpeptidase (GGT) levels influences atherosclerotic plaque development in apparently healthy people.Materials and methods: The study population included people who had received an annual health checkup for more than 7 years and had no evidence of carotid plaque at baseline. We investigated the risk factors for carotid plaque occurrence using the Cox proportional hazards model.Results: A total of 107 people (76 men and 31 women; median age, 49 years) were enrolled. At baseline, fatty liver and a serum GGT level ≥50 U/L were observed in 13 and 38 …
Comparison Of Atrial Fibrillation Predictors In Patients With Acute Coronary Syndrome Using Ticagrelor Or Clopidogrel, Engi̇n Algül, Hamza Sunman, Muhammet Dural, İlki̇n Guli̇yev, Mert Aker, Mehmet Ali̇ Felekoğlu, Mehmet Erat, Murat Tulmaç, Sadik Açikel, Tolga Çi̇men
Comparison Of Atrial Fibrillation Predictors In Patients With Acute Coronary Syndrome Using Ticagrelor Or Clopidogrel, Engi̇n Algül, Hamza Sunman, Muhammet Dural, İlki̇n Guli̇yev, Mert Aker, Mehmet Ali̇ Felekoğlu, Mehmet Erat, Murat Tulmaç, Sadik Açikel, Tolga Çi̇men
Turkish Journal of Medical Sciences
Background/aim: Ticagrelor is a drug widely used in patients with acute coronary syndromes (ACS) that specifically increases the plasma level of adenosine, which is likely to cause atrial fibrillation (AF). Therefore, in this study we aimed to investigate the electrocardiographic and echocardiographic predictors of AF development after P2Y12 receptor antagonists in ACS patients.Materials and methods: This cross-sectional study included 831 patients with ACS (486 [58.5%] with ST elevated myocardial infarction [STEMI] and 345 [41.5%] with non-ST elevated myocardial infarction [NSTEMI]). Patients were divided into ticagrelor (n = 410) and clopidogrel (n = 421) groups. P wave properties including P wave …
Plasma Thrombin-Activatable Fibrinolysis Inhibitor (Tafi) Antigen Levels In Acromegaly Patients In Remission, Mehmet Erdoğan, Mustafa Özbek, Erdem Akbal, Kemal Üreten
Plasma Thrombin-Activatable Fibrinolysis Inhibitor (Tafi) Antigen Levels In Acromegaly Patients In Remission, Mehmet Erdoğan, Mustafa Özbek, Erdem Akbal, Kemal Üreten
Turkish Journal of Medical Sciences
Background/aim: Acromegaly is associated with increased morbidity andmortality, mostly due to cardiovascular complications.Plasma thrombin-activatable fibrinolysis inhibitor (TAFI) antigen levels are associated with coagulation/fibrinolysis and inflammation. Plasma TAFI may play a role in arterial thrombosis in cardiovascular diseases. In this study, it was aimed to evaluate the thrombin-activatable fibrinolysis inhibitor (TAFI) antigen and homocysteine levels in patients with acromegaly and healthy control subjects.Materials and methods: Plasma TAFI antigen and homocysteine levels in 29 consecutive patients with acromegaly and 26 age-matched healthy control subjects were measured. All patients included in the study were in remission. The TAFIa/ai antigen in the plasma samples …
Il-1rn Vntr, Il-2(-330), And Il-4 Vntr Gene Polymorphisms In Patients With Chronic Rhinosinusitis With Sinonasal Polyposis, Gökhan Kuran, Hüseyi̇n Aslan, Süheyl Haytoğlu, Özge Özalp Yüreği̇r, Sevcan Tuğ Bozdoğan
Il-1rn Vntr, Il-2(-330), And Il-4 Vntr Gene Polymorphisms In Patients With Chronic Rhinosinusitis With Sinonasal Polyposis, Gökhan Kuran, Hüseyi̇n Aslan, Süheyl Haytoğlu, Özge Özalp Yüreği̇r, Sevcan Tuğ Bozdoğan
Turkish Journal of Medical Sciences
Background/aim: Sinonasal polyposis is a complex chronic disease displaying contributions from multiple genetic and environmental factors. In this study, we analyzed possible genetic factors that increase susceptibility to this widespread inflammatory disease. Materials and methods: A total of 176 adult patients, including 78 patients with sinonasal polyposis and 98 healthy controls, were analyzed for IL-1RN VNTR, IL-2(-330), and IL-4 VNTR gene polymorphisms using polymerase chain reaction and enzyme restriction.Results: IL-1RN and IL-4 VNTR polymorphisms were notably associated with sinonasal polyposis (P = 0.0001 and P = 0.036, respectively); however, regarding the IL-2(-330) gene polymorphism, no significant difference was shown between …
Effect Of Variation In Mirna-Binding Site (Rs8176318) Of The Brca1 Gene In Breast Cancer Patients, Mushtaq Ahmad, Fazal Jalil, Muti Ul Haq, Aftab Shah
Effect Of Variation In Mirna-Binding Site (Rs8176318) Of The Brca1 Gene In Breast Cancer Patients, Mushtaq Ahmad, Fazal Jalil, Muti Ul Haq, Aftab Shah
Turkish Journal of Medical Sciences
Background/aim: A variation in the 3 prime untranslated regions (3?-UTRs) affects the binding of microRNA (miRNA) to the breast cancer (BC) susceptibility gene 1 (BRCA1) gene, and thus regulate its expression. In this study, the consequences of a variation in the miRNA-binding site (rs8176318G>T) in the 3?-UTRs of BRCA1 and its association with the risk of BC were investigated.Materials and methods: The selected variation (rs8176318G>T) was genotyped in BC patients (n = 300) and healthy controls (n = 300) using allele-specific polymerase chain reaction (PCR) [tetra-primer amplification refractory mutation system-PCR (T-ARMS-PCR)]. The results of the T-ARMS-PCR were further …
Normative Hippocampal Volumetric Measurements Using Magnetic Resonance Imaging, Meltem Özdemi̇r, Handan Soysal, Önder Eraslan, Alper Di̇lli̇
Normative Hippocampal Volumetric Measurements Using Magnetic Resonance Imaging, Meltem Özdemi̇r, Handan Soysal, Önder Eraslan, Alper Di̇lli̇
Turkish Journal of Medical Sciences
Background/aim: A wide variety of neurological and psychiatric disorders have been shown to be closely related to changes in hippocampal volume (HV). It appears that hippocampal volumetry will be an indispensable part of clinical practice for a number of neuropsychiatric disorders in the near future. The aim of this study was to establish a normative data set for HV according to age and sex in the general population.Materials and methods: Hippocampal magnetic resonance imaging scans of 302 healthy volunteers were obtained using a 1.5 T unit with a 20-channel head coil. The hippocampal volumetric assessment was conducted using the volBrain …
Evaluation Of Interleukin-23 Receptor (Il-23r) Gene Polymorphisms And Serum Il-23 Levels In Patients With Psoriasis, Başak Fi̇li̇z, Mehmet Yildirim, Kuyaş Heki̇mler Öztürk, Fevzi̇ye Burcu Şi̇ri̇n, Seda Çeli̇k, İjlal Erturan, Selma Korkmaz, Hi̇kmet Orhan
Evaluation Of Interleukin-23 Receptor (Il-23r) Gene Polymorphisms And Serum Il-23 Levels In Patients With Psoriasis, Başak Fi̇li̇z, Mehmet Yildirim, Kuyaş Heki̇mler Öztürk, Fevzi̇ye Burcu Şi̇ri̇n, Seda Çeli̇k, İjlal Erturan, Selma Korkmaz, Hi̇kmet Orhan
Turkish Journal of Medical Sciences
Background/aim: IL-23R gene polymorphisms and the association of these polymorphisms with serum IL-23 levels were investigated in patients with psoriasis in the current study. Materials and methods: Sixty-seven patients with psoriasis who were admitted to our dermatology outpatient clinic and 67 healthy controls were included in the study. Polymorphisms of the IL-23R gene were determined by KASP-PCR method, and serum IL-23 levels were determined by ELISA method.Results: The distribution of IL-23R gene polymorphisms rs2201841, rs11209026, rs7530511, rs1343152, and rs11465804 was not significantly different in the patient and control groups. The AA genotype of the rs2201841 locus in males and the …
Importance Of 14-3-3eta, Anti-Carp, And Anti-Sa In The Diagnosis Of Seronegative Rheumatoid Arthritis, Emrah Salman, Sali̇h Çeti̇ner, Bariş Boral, Fi̇li̇z Ki̇bar, Eren Erken, Emi̇ne Duygu Ersözlü, Suade Özlem Badak, Reyhan Bi̇li̇ci̇ Salman, Yaşar Sertdemi̇r, Alev Çeti̇n Duran, Akgün Yaman
Importance Of 14-3-3eta, Anti-Carp, And Anti-Sa In The Diagnosis Of Seronegative Rheumatoid Arthritis, Emrah Salman, Sali̇h Çeti̇ner, Bariş Boral, Fi̇li̇z Ki̇bar, Eren Erken, Emi̇ne Duygu Ersözlü, Suade Özlem Badak, Reyhan Bi̇li̇ci̇ Salman, Yaşar Sertdemi̇r, Alev Çeti̇n Duran, Akgün Yaman
Turkish Journal of Medical Sciences
Background/aim: Rheumatoid arthritis (RA) is an autoimmune disease characterized by synovial inflammation. The study aimed to assess serum 14-3-3eta, anti-CarP, and anti-Sa in seronegative RA (SNRA) patients who were treatment-naïve as well as in healthy subjects. This is the first study in the literature to examine these autoantibodies together in SNRA patients. Materials and methods: Forty-five treatment-naïve SNRA patients and 45 healthy subjects were recruited. Drugs change the levels of autoantibodies; therefore, patients who took any medication had been excluded from our study. Anti-carbamylated protein, anti-Sa, and 14-3-3eta were measured by using three different ELISA kits.Results: Median serum concentration of …
Nicotinamide N-Methyltransferase Expression And Its Association With Phospho-Akt, P53 Expression, And Survival In High-Grade Endometrial Cancer, Serra Akar, İsmai̇l Harmankaya, Serdar Ugras, Çeti̇n Çeli̇k
Nicotinamide N-Methyltransferase Expression And Its Association With Phospho-Akt, P53 Expression, And Survival In High-Grade Endometrial Cancer, Serra Akar, İsmai̇l Harmankaya, Serdar Ugras, Çeti̇n Çeli̇k
Turkish Journal of Medical Sciences
Background/aim: Nicotinamide N-methyltransferase (NNMT) is an enzyme that is overexpressed in malignancies. NNMT expression has not been previously studied in endometrial cancer (EC). Increased phospho-Akt (pAkt) levels in response to NNMT overexpression have been reported in in vitro studies of different cancer types. We assayed NNMT expression in primary and metastatic high-grade EC and investigated the relationship of NNMT with p53, pAkt, and survival. Materials and methods: NNMT, pAkt, and p53 expressions were assayed in 100 tissue samples of benign endometria, primary EC, and metastatic EC by immunohistochemistry. Results: The NNMT immunoreactivity score was significantly higher in primary high-grade EC …
Serum Zinc Levels In Seborrheic Dermatitis: A Case-Control Study, Ezgi̇ Aktaş Karabay, Asli Aksu Çerman
Serum Zinc Levels In Seborrheic Dermatitis: A Case-Control Study, Ezgi̇ Aktaş Karabay, Asli Aksu Çerman
Turkish Journal of Medical Sciences
Background/aim:Malassezia colonization, sebaceous gland activity, hormones, immune system defects, environmental factors, and the interactions between these factors are thought to contribute to the pathogenesis of seborrheic dermatitis (SD). Zinc, an essential element, is involved in many biological processes including the ones that contribute to the development of SD. The aim of this study is to evaluate serum zinc levels in patients with SD.Materials and methods: Forty-three patients with SD and 41 healthy controls were enrolled in the study. Disease activity was assessed by the Seborrheic Dermatitis Area and Severity Index by a single dermatologist. Serum zinc levels of all subjects …
Comparison Of Bactericidal And Fungicidal Efficacy Of Antiseptic Formulations According To En 13727 And En 13624 Standards, Asli Şahi̇ner, Ece Halat, Evren Alğin Yapar
Comparison Of Bactericidal And Fungicidal Efficacy Of Antiseptic Formulations According To En 13727 And En 13624 Standards, Asli Şahi̇ner, Ece Halat, Evren Alğin Yapar
Turkish Journal of Medical Sciences
Background/aim: In this study, the antibacterial and antifungal properties of the five most commonly used antiseptic formulations were evaluated in terms of different contact times and organic conditions. Materials and methods: Solutions of chlorhexidine digluconate, povidone iodine, isopropyl alcohol, hydrogen peroxide, and tincture of iodine were prepared and tested according to European standards EN 13727 and EN 13624 with different parameters.Results: The results showed that isopropyl alcohol (70% v/v) and tincture of iodine (2%) had greater bactericidal and fungicidal activity against the four tested bacteria and two fungi in all conditions.Conclusion: When the results of the five different active substances …
Shear Wave Versus Strain Elastography In The Differentiation Of Benign And Malignant Breast Lesions, Aykut Gürüf, Mesut Öztürk, İlkay Koray Bayrak, Ahmet Veysel Polat
Shear Wave Versus Strain Elastography In The Differentiation Of Benign And Malignant Breast Lesions, Aykut Gürüf, Mesut Öztürk, İlkay Koray Bayrak, Ahmet Veysel Polat
Turkish Journal of Medical Sciences
Background/aim: To evaluate and compare the diagnostic performances of shear wave elastography (SWE) and strain elastography (SE) in the differentiation of benign and malignant breast lesions.Materials and methods: The current study included 87 breast lesions in 84 patients. The Breast Imaging Reporting and Data System (BIRADS) categories were determined with ultrasound features. The maximum shear wave velocity (SWV), mean SWV, maximum SWV to fat SWV ratio, and mean SWV to fat SWV ratio were measured using SWE. The strain ratio (SR) was calculated as the ratio of lesion strain to the adjacent fat strain using SE. Receiver operating characteristic (ROC) …