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Effects Of Hydro- And Nano-Priming Treatments On Seed Germination And Metabolism In Sugar Beet (Beta Vulgaris L.), Sarah Jorjani, Ömer Can Ünüvar, Songül Gürel, Ekrem Gürel
Effects Of Hydro- And Nano-Priming Treatments On Seed Germination And Metabolism In Sugar Beet (Beta Vulgaris L.), Sarah Jorjani, Ömer Can Ünüvar, Songül Gürel, Ekrem Gürel
Turkish Journal of Botany
This study examined the effects of hydropriming and nanopriming on the germination and physiological parameters of sugar beet seeds. Seeds were treated with distilled water as a traditional method and with TiO2 nanoparticle solutions at concentrations of 5, 10, and 15 ppm as an advanced method. Seeds were soaked for 3, 6, and 9 h, followed by postpriming maintenance for 10 and 45 days. T he results indicated no statistically significant differences in germination rates between the control and primed groups. Both priming methods markedly increased alpha-amylase activity and chlorophyll content, indicating improved metabolic and photosynthetic potential. Notably, nanopriming for …
Modeling Global Ecological Niche Shifts Of Osyris Spp. Under Climate Change Scenarios: Conservation Priorities For A Threatened Genus, Meng Ting-Yao, Han Shun-Long, He Xiang-Tian, Wu Ya-Ni, Fengjuan Mou
Modeling Global Ecological Niche Shifts Of Osyris Spp. Under Climate Change Scenarios: Conservation Priorities For A Threatened Genus, Meng Ting-Yao, Han Shun-Long, He Xiang-Tian, Wu Ya-Ni, Fengjuan Mou
Turkish Journal of Botany
The genus Osyris L. comprises ecologically and economically important evergreen shrubs or small trees, with particular African species currently threatened by unsustainable exploitation. This study projected potential ecological niche shifts for Osyris under four Shared Socioeconomic Pathways (SSPs) using digitized herbarium specimen localities and 20 environmental variables. The genus currently occupies a broad range between 41.32°N–34.85°S latitude and 9.27°W–109.03°E longitude, at elevations from 0 to 3900 m. High-suitability areas cluster primarily in the European-Mediterranean region, eastern/southern Africa, western South America, and Southeast Asia. Projections indicate a significant decline in high-suitability area under all SSP scenarios (SSP126, SSP245, SSP370, SSP585) compared …
Mycorrhiza-Mediated Physiological Responses Of Shallot Against Twisted Disease And Drought Stress, Krisnanda Surya Dharma, Ani Widiastuti, Suryanti Suryanti
Mycorrhiza-Mediated Physiological Responses Of Shallot Against Twisted Disease And Drought Stress, Krisnanda Surya Dharma, Ani Widiastuti, Suryanti Suryanti
Turkish Journal of Botany
Shallot, a strategic horticultural commodity in Indonesia, is susceptible to biotic stress (e.g., twisted disease) and abiotic stress (e.g., drought). Mycorrhizal fungi offer an environmentally friendly solution to enhance plant resilience. This study evaluated the effects of mycorrhizal application on shallot plants against twisted disease (Fusarium acutatum) and drought stress. Using a randomized complete block design, we assessed growth, disease resistance, and physiological responses. Data were analyzed using analysis of variance followed by Tukey’s honestly significant difference test at a 95% confidence level. Results indicated that mycorrhizal application reduced both the severity and rate of twisted disease development in shallots. …
Taxonomic Significance Of Stem And Leaf Anatomy And Pollen And Seed Micromorphological Characters In The Papaver (Poppy) Sect. Rhoeadium From Türkiye, Esengül Özkaymakoğlu, Osman Tugay, Yavuz Bülent Köse, Deni̇z Ulukuş, Bayram Atasagun, Meti̇n Armağan, Ferhat Celep
Taxonomic Significance Of Stem And Leaf Anatomy And Pollen And Seed Micromorphological Characters In The Papaver (Poppy) Sect. Rhoeadium From Türkiye, Esengül Özkaymakoğlu, Osman Tugay, Yavuz Bülent Köse, Deni̇z Ulukuş, Bayram Atasagun, Meti̇n Armağan, Ferhat Celep
Turkish Journal of Botany
The poppy (Papaver) has beautiful flowers that attract the attention of not only taxonomists but also the public. However, it also presents several taxonomic problems. This study examines 13 taxa of Papaver sect. Rhoeadium, including the following species native to Türkiye: P. purpureomarginatum, P. dubium subsp. dubium, P. dubium subsp. laevigatum, P. arachnoideum, P. arenarium, P. commutatum subsp. euxinum, P. guerlekense, P. rhopalothece, P. stylatum, P. clavatum, P. syriacum, P. rhoeas, and P. postii. Plant specimens were collected from natural populations, and anatomical investigations were carried out on stem and leaf cross-sections. Pollen and seed features were examined using both …
Complete Genome Characterization Of A New Alphapartitivirus Identified In The Ectomycorrhizal Fungus Lactarius Mediterraneensis, Aigul Kali̇yeva, Ergi̇n Şahi̇n, Gülce Edi̇ş, Ilgaz Akata
Complete Genome Characterization Of A New Alphapartitivirus Identified In The Ectomycorrhizal Fungus Lactarius Mediterraneensis, Aigul Kali̇yeva, Ergi̇n Şahi̇n, Gülce Edi̇ş, Ilgaz Akata
Turkish Journal of Botany
Viruses that naturally infect fungi capable of forming mycorrhizal symbioses remain poorly studied. In the present study, a new partitivirus associated with the basidiomycete mycorrhizal fungus Lactarius mediterraneensis was identified and characterized, and it was designated as Lactarius mediterraneensis partitivirus 1 (LmPV1). The complete genome of LmPV1 was determined through high throughput sequencing of double-stranded RNA (dsRNA) extracts and confirmed by Sanger sequencing of RLM-RACE PCR amplicons. T he genome comprises two dsRNA segments, 1899 bp and 1957 bp, each containing a single open reading frame (ORF) a putative RNA-dependent RNA polymerase (RdRp) and a capsid protein (CP). Comparative analysis …
A Novel Strategy Of Mycorrhizal Fungi Usage To Enhance Crop Resilience In Saline Environments: Biopriming With Serendipita Indica, Tuğba Özteki̇n, Meli̇sa Ayişiği, Lale Yildiz Aktaş
A Novel Strategy Of Mycorrhizal Fungi Usage To Enhance Crop Resilience In Saline Environments: Biopriming With Serendipita Indica, Tuğba Özteki̇n, Meli̇sa Ayişiği, Lale Yildiz Aktaş
Turkish Journal of Botany
Soil salinization is a critical global challenge, threatening agricultural productivity by imposing osmotic stress, ionic toxicity, and oxidative imbalance in plants. This study investigated the potential of Serendipita indica biopriming to enhance salt stress tolerance in maize (Zea mays L. cv. Simon) seedlings through comprehensive physiological and biochemical analyses under controlled conditions. Maize seeds were bioprimed with different concentrations of mycorrhizal fungi S. indica spores and exposed to varying NaCl concentrations (0, 50, 100, and 200 mM). Nonprimed maize seedlings had a gradual reduction in seed vigor index, reaching about 93.56% in 200 mM NaCl treatment. Under nonsaline conditions, S. …
Hormetic Doses Of Lead Metal Ion Stimulated Photosynthetic Attributes In Brassica Juncea During Various Stages Of Growth, Shalini Dhiman, Arun Dev Singh, Nitika Kapoor, Renu Bhardwaj
Hormetic Doses Of Lead Metal Ion Stimulated Photosynthetic Attributes In Brassica Juncea During Various Stages Of Growth, Shalini Dhiman, Arun Dev Singh, Nitika Kapoor, Renu Bhardwaj
Turkish Journal of Botany
Low doses of lead (Pb) ions were used in the present study to investigate their effects on photosynthetic efficiency in Brassica juncea. Plants of B. juncea grown for 30, 45, and 60 days were analysed for root and shoot length, pigment content, gas exchange, chlorophyll fluorescence, primary and secondary metabolites, and nonenzymatic antioxidant responses under exposure to hormetic doses of Pb2+. The findings show that low levels of Pb2+ (especially 18- and 36-µM Pb treatments) improve gas exchange metrics, chlorophyll fluorescence parameters, root and shoot growth, and increased amounts of chlorophyll, carotenoid, xanthophyll and low amounts of pheophytin as compared …
Zonation-Dependent Distribution Of Microplastic Occurrence In Patella Caerulea From Mersin Coast, Türkiye, Ezgi̇ Deği̇rmenci̇, Nuray Çi̇ftçi̇, Sedat Gündoğdu, Deni̇z Ayas
Zonation-Dependent Distribution Of Microplastic Occurrence In Patella Caerulea From Mersin Coast, Türkiye, Ezgi̇ Deği̇rmenci̇, Nuray Çi̇ftçi̇, Sedat Gündoğdu, Deni̇z Ayas
Turkish Journal of Zoology
Increasing plastic pollution has become a critical environmental issue, leading to challenges in management. Specifically, microplastics (MPs) are of particular concern because they can persist in aquatic ecosystems and adversely affect marine organisms. The objective of this study was to assess the occurrence of MPs in the soft tissues of Patella caerulea (Linnaeus, 1758) collected from the Mersin Viranşehir coastal area. As no specimens were found in the supralittoral zone, the decision was taken to conduct sampling only in the mediolittoral and infralittoral zones. The total sampling area was 24 m2 divided into three 4-m2 plots in each zone. A …
Blinking Without Eyelids: First Video-Documented Evidence Of A Blink-Like Reflex In Ophisops Elegans (Reptilia: Lacertidae), Turan Meri̇ç Çelebi̇, Yusuf Çeli̇kaği, Tuana Kinay, Arda Cem Kuyucu, Muammer Kurnaz, Mehmet Kürşat Şahi̇n
Blinking Without Eyelids: First Video-Documented Evidence Of A Blink-Like Reflex In Ophisops Elegans (Reptilia: Lacertidae), Turan Meri̇ç Çelebi̇, Yusuf Çeli̇kaği, Tuana Kinay, Arda Cem Kuyucu, Muammer Kurnaz, Mehmet Kürşat Şahi̇n
Turkish Journal of Zoology
Eyelids play a crucial role in protecting the eyes of vertebrates; however, certain reptile species, such as Ophisops elegans, completely lack movable eyelids. In this study, we present the first video-documented evidence of a blink-like reflex in O. elegans, captured through endoscopic field observations and corroborated by laboratory video analysis. The observed movement consisted of a brief convex deformation of the ocular surface, lasting approximately 0.3 s and resembling a blink despite the presence of a fixed transparent brille. This behavior was observed once in the field and twice under controlled laboratory conditions. We propose that O. elegans may employ …
Growth Patterns And The Shift From Predominantly Female To Balanced Sex Ratios In Carassius Gibelio (Bloch, 1782): A Comparative Study Of Lotic And Lentic Populations In Serbia, Tamara Mitić, Jelena Čanak Atlagić, Ana Marić, Jelena Stanković Ristić, Nikola Marinković, Momir Paunović, Predrag Simonović
Growth Patterns And The Shift From Predominantly Female To Balanced Sex Ratios In Carassius Gibelio (Bloch, 1782): A Comparative Study Of Lotic And Lentic Populations In Serbia, Tamara Mitić, Jelena Čanak Atlagić, Ana Marić, Jelena Stanković Ristić, Nikola Marinković, Momir Paunović, Predrag Simonović
Turkish Journal of Zoology
Since its introduction into Serbian watercourses, the invasive Carassius gibelio (Bloch, 1782) (Prussian carp) has spread rapidly. This paper provides an up-to-date overview of the sex ratio, age structure, and growth parameters in Serbian populations of this fish and describes how growth varies in two contrasting ecosystems: lotic and lentic. A total of 133 individuals were sampled. The individuals from lentic habitats were longer on average, with no significant differences in average weight or age between the two ecosystem types. There was a difference in the sex ratio between the ecosystems, as indicated by a higher proportion of males in …
Habitat Diversity Or Altitudinal Gradient? Which Factor Better Explains Ground Beetle (Coleoptera: Carabidae) Biodiversity? A Case Study From Davraz Mountain (Isparta, Türkiye), Ebru Ceren Fi̇dan, Ali̇ Gök
Habitat Diversity Or Altitudinal Gradient? Which Factor Better Explains Ground Beetle (Coleoptera: Carabidae) Biodiversity? A Case Study From Davraz Mountain (Isparta, Türkiye), Ebru Ceren Fi̇dan, Ali̇ Gök
Turkish Journal of Zoology
Ground beetle (Carabidae) species diversity and spatial distribution were surveyed across five habitat types along an elevational gradient on Davraz Mountain, a biogeographical transition area in southwestern Türkiye. The analyses showed that habitat heterogeneity—particularly soil moisture and texture—exerts a stronger influence on carabid diversity than elevation. Sørensen’s and Jaccard similarity indices showed strong faunal overlap between some sampling areas, while multivariate principal components and canonical correspondence analyses verified distinct environmental gradients influencing community structure. Diversity indices indicated varying levels of species richness and evenness across sampling areas. The data highlight the importance of fine-scaled habitat features in driving ground beetle …
Dna Metabarcoding Approach To The Determination Of The Diet Spectrum Of The Common Sunbleak Leucaspius Delineatus (Heckel, 1843), Elena V. Dzyuba, Yurij S. Bukin, Bakhtiar E. Bogdanov, Yulia P. Sapozhnikova, Natalia N. Denikina
Dna Metabarcoding Approach To The Determination Of The Diet Spectrum Of The Common Sunbleak Leucaspius Delineatus (Heckel, 1843), Elena V. Dzyuba, Yurij S. Bukin, Bakhtiar E. Bogdanov, Yulia P. Sapozhnikova, Natalia N. Denikina
Turkish Journal of Zoology
The common sunbleak (Leucaspius delineatus) is an invasive fish found in Siberian water bodies, the trophic interactions and impact on local ecosystems of which remain poorly understood. Traditional diet analyses are limited by the mechanical damage to the prey. For the present study, therefore, we employed DNA metabarcoding of the cytochrome c oxidase I (cox1) gene to analyze the digestive tract contents of the common sunbleak obtained from Irkutsk Reservoir. Our analysis revealed 53 operational taxonomic units (OTUs), with sequences of amphibiotic insects (58.66%) and fish (34.10%) being the most prevalent. A significant proportion of the fish DNA, including sequences …
Bioerosion And Encrustation As Paleoenvironmental Indicators In Upper Cretaceous Corals, Aruma Formation, Saudi Arabia, Abdelbaset S. El-Sorogy, Huriye Demi̇rcan, Khaled Al-Kahtany, Taisser Zumlot, Talal Alharbi, Mohamed Tawfik
Bioerosion And Encrustation As Paleoenvironmental Indicators In Upper Cretaceous Corals, Aruma Formation, Saudi Arabia, Abdelbaset S. El-Sorogy, Huriye Demi̇rcan, Khaled Al-Kahtany, Taisser Zumlot, Talal Alharbi, Mohamed Tawfik
Turkish Journal of Earth Sciences
This study documents and interprets bioerosion and encrustation traces on Upper Cretaceous scleractinian corals from the Hajajah Member of the Aruma Formation in northern Khashm Buwaibiyat, central Saudi Arabia. Fieldwork in 2023 and 2024 involved detailed bed-by-bed stratigraphic logging, ichnological assessment, and fossil collection across marl and limestone units. A total of 213 coral specimens with bioerosional features were analyzed, leading to the identification of 10 ichnospecies across 5 ichnogenera, including Gastrochaenolites, Entobia, Caulostrepsis, Rogerella, and Labyrintichnus. These traces reflect a range of ethological categories, primarily domichnia, indicating permanent dwelling structures by polychaetes, sponges, bivalves, barnacles, and crustaceans. The Hajajah …
Geochemical Characteristics And Ree Potential Of Red Soils In The Seydişehir–Akseki Region (Türkiye), Muazzez Çeli̇k Karakaya, Necati̇ Karakaya, Aydin Rüşen, Cem Saraç
Geochemical Characteristics And Ree Potential Of Red Soils In The Seydişehir–Akseki Region (Türkiye), Muazzez Çeli̇k Karakaya, Necati̇ Karakaya, Aydin Rüşen, Cem Saraç
Turkish Journal of Earth Sciences
The karst-type bauxite deposits located in southwestern Türkiye represent the most significant bauxite resources in the country. Surrounding these bauxite deposits are widespread red soil deposits of varying sizes, developed over lithologically diverse rocks. This study aims to investigate the origin of these red soils, which were examined in two distinct groups based on their spatial relationship to the underlying geology. The first group of red soils is found on or within the fractures of karstic limestones, while the second group is primarily located in proximity to ophiolitic rocks. The investigation focused on the physical properties, as well as the …
A Deep Learning-Based Real-Time No-Reference Image Decolorization Network With Perceptual Preservation, Mengjuan Zhao, Yitao Liang, Weiya Shi, Juan Xia
A Deep Learning-Based Real-Time No-Reference Image Decolorization Network With Perceptual Preservation, Mengjuan Zhao, Yitao Liang, Weiya Shi, Juan Xia
Turkish Journal of Electrical Engineering and Computer Sciences
Currently, grayscale images are preferred as input data for some specific vision tasks. Decolorization is the transformation of a color image into a grayscale image. Efficient decolorization algorithms can improve the overall task efficiency, while perceptual preservation in decolorization can provide more information for further processing. In recent research, traditional methods focus on preserving contrast or detail information with little attention to perceptual features. Deep-learning methods are beginning to consider perceptual preservation, but they run inefficiently. In addition, the decolorization methods lack the optimal target grayscale images for reference. Therefore, we propose a new deep learning-based real-time no-reference decolorization network …
Effects Of Different Perfluoroalkyl Substances On Rice Morphology, Physiology, And Biochemistry, Maryam M. Alomran, Muhammad Aqeel, Noreen Khalid, Noreen Akhter, Muhammad Kashif Irshad, Suliman Mohammed Suliman Alghanem, Fahad Mohammed Alzuaibr, Saher Nawaz, Omar Mahmoud Alzoubi, Muhammad Usman Akbar, Ali Noman
Effects Of Different Perfluoroalkyl Substances On Rice Morphology, Physiology, And Biochemistry, Maryam M. Alomran, Muhammad Aqeel, Noreen Khalid, Noreen Akhter, Muhammad Kashif Irshad, Suliman Mohammed Suliman Alghanem, Fahad Mohammed Alzuaibr, Saher Nawaz, Omar Mahmoud Alzoubi, Muhammad Usman Akbar, Ali Noman
Turkish Journal of Agriculture and Forestry
Perfluoroalkyl substances (PFASs) are synthetic organic compounds that have not been extensively studied in natural environments. The current study aimed to explore how PFASs, including perfluorooctane sulfonic acid (PFOS), perfluorobutane sulfonate (PFBS), perfluorohexanoate (PFHxA), perfluorotetradecanoate (PFTeDA), and perfluorobutanoate (PFBA), affect rice plants and influence their metabolism. These substances had a notable impact on root and shoot growth, reducing fresh and dry weights across various treatments compared to the control. These attributes were the least affected by PFOS treatment. PFBA treatment had significant adverse effects on chlorophyll a, b, and total chlorophyll levels, followed by the effects of PFHxA and PFTeDA. …
Effect Of Nettle (Urtica Dioica L.) Seed Powder Supplementation On Some Important Quality Characteristics Of Cakes, Esra İrem Can, Kadi̇r Çebi̇
Effect Of Nettle (Urtica Dioica L.) Seed Powder Supplementation On Some Important Quality Characteristics Of Cakes, Esra İrem Can, Kadi̇r Çebi̇
Turkish Journal of Agriculture and Forestry
The nutritional adjustment of food products has gained popularity in recent years as consumer interest in healthy eating has increased. Cake is a widely consumed cereal-based product containing such key nutrients as carbohydrate, fat, protein, fiber, vitamins, and minerals. In the present study, crust and crumb color, specific volume, microstructure, antimicrobial activity, total phenolic content, antioxidant activity, and sensory analyses were evaluated in four cake groups: a control cake (IT0) and cakes supplemented with 1% (IT1), 3% (IT2), and 5% (IT3) nettle seed powder. The addition of nettle seed powder to the cakes significantly reduced the crust (L*, a* and …
Jujubenet: A Dual-Stage Spectral Reconstruction Network For Rapid Jujube Moisture Content Estimation, Yalei Xu, Yang Li, Jing Nie, Jingbin Li
Jujubenet: A Dual-Stage Spectral Reconstruction Network For Rapid Jujube Moisture Content Estimation, Yalei Xu, Yang Li, Jing Nie, Jingbin Li
Turkish Journal of Agriculture and Forestry
Spectral analysis methods can nondestructively assess the quality of agricultural products but are limited by imaging speed and equipment costs. Therefore, they have not yet been fully integrated into engineering practices. This paper presents JujubeNet, a two-stage hyperspectral reconstruction model for detecting moisture content in jujubes. The first stage utilizes a generative pretrained Pix2Pix generative adversarial network (GAN) to generate RGB images of jujubes that mimic real camera styles and are pixel-to-pixel aligned with hyperspectral images. The second stage uses a transformer-based spectral reconstruction model to achieve hyperspectral reconstruction. Additionally, we developed a moisture content detection model based on hyperspectral …
Utilization Of Phytogenic Silver Nanoparticles And Bacterial Agents For The Management Of Citrus Canker Disease, Zainab Jamil, Tariq Mukhtar, Muhammad Usman Raja, Muhammad Shahbaz, Jaya Seelan S. Seelan, Muhammed Tatar, Amjad Ali, Noor Fatima, Rahma Bejaoui, Ayşe Usanmaz Bozhüyük
Utilization Of Phytogenic Silver Nanoparticles And Bacterial Agents For The Management Of Citrus Canker Disease, Zainab Jamil, Tariq Mukhtar, Muhammad Usman Raja, Muhammad Shahbaz, Jaya Seelan S. Seelan, Muhammed Tatar, Amjad Ali, Noor Fatima, Rahma Bejaoui, Ayşe Usanmaz Bozhüyük
Turkish Journal of Agriculture and Forestry
Citrus is one of the most important and widely cultivated fruit crops globally. However, its productivity is increasingly threatened by various diseases, with bacterial infections being particularly the most destructive. Among these, citrus canker, caused by Xanthomonas axonopodis pv. citri (Xac), poses a significant challenge, requiring effective management strategies. Traditional approaches have shown limited success, but nanotechnology has emerged as a promising alternative for disease control. In this study, Xanthomonas spp. was isolated from two locations: Koont Farm and the National Agricultural Research Centre (NARC) citrus orchards in Islamabad, Pakistan. The isolates were identified through morpho-biochemical methods. Moreover, three Bacillus …
Optimizing Cultivated Land Productivity Through Integrated Fertilization Strategies And Uav-Assisted Management, Kejun Wang
Turkish Journal of Agriculture and Forestry
This study investigates the impact of long-term fertilization modes on crop health and productivity using unmanned aerial vehicle (UAV)-assisted monitoring and a Q-learning-based approach for optimized fertilization strategies. An approximate state-matching Q-learning algorithm was developed to improve the efficiency of agricultural UAVs in fertilization tasks. The spatiotemporal patterns of cultivated land productivity under different fertilization regimes were analyzed in a long-term experiment. An evaluation system for cultivated land health productivity was established. The results indicated that the Q-learning algorithm enabled UAVs to achieve efficient task completion. QLASM outperformed traditional methods on all metrics. QLASM achieved a 92% task completion rate …
Effects Of Different Mixing Ratios Of Common Vetch And Oats On Forage Yield And Quality, Meli̇h Okcu, Sedat Severoğlu, İbrahi̇m Kavuncu
Effects Of Different Mixing Ratios Of Common Vetch And Oats On Forage Yield And Quality, Meli̇h Okcu, Sedat Severoğlu, İbrahi̇m Kavuncu
Turkish Journal of Agriculture and Forestry
This study investigates the optimal mixing ratios of common vetch (Vicia sativa L., CV) and oats (Avena sativa L., O) for enhanced forage yield and quality in the ecological conditions of Erzurum Province. The research was conducted over two growing seasons with three replications in a randomized complete block design (RCBD). Specifically, three common vetch cultivars (Gülhan, Albayrak, Kubilay) and one oat cultivar (Kupa) were evaluated by sowing as sole crops and in different ratios (25% vetch + 75% oat, 50% vetch + 50% oat, 75% vetch + 25% oat). The analyzed parameters included hay forage yield (HFY), dry matter …
Exploring Bioactive Components Of Sugar Bean With Some Data Mining Algorithms: Relationships Between Antioxidants, Enzyme Inhibitors, And Minerals, İrem Ayran Çolak
Exploring Bioactive Components Of Sugar Bean With Some Data Mining Algorithms: Relationships Between Antioxidants, Enzyme Inhibitors, And Minerals, İrem Ayran Çolak
Turkish Journal of Agriculture and Forestry
Sugar bean (Phaseolus vulgaris L.) is a legume of notable nutritional and functional value, and its genotypes have substantial variation in bioactive compounds, antioxidant activity, mineral composition, and enzyme inhibition properties. This study aimed to comprehensively evaluate the biochemical and functional diversity of 10 sugar bean genotypes using data mining algorithms to identify superior candidates for functional food and nutraceutical development. Associations between the phytochemical profiles of sugar bean genotypes and their bioactivity, antioxidant capacity, and enzyme inhibition were modeled with classification and regression trees (CART), random forests (RF), and multivariate adaptive regression splines (MARS), while one-way ANOVA quantified varietal …
Gamma Secretase Inhibitors, Dapt And Mk0752, Exhibit Synergistic Anticancer Effects With Cisplatin And Docetaxel In 2d And 3d Models Of Breast Cancer, Kübra Telli̇, Johannes Gubat, Padraig D'Arcy, Özden Yalçin Özuysal
Gamma Secretase Inhibitors, Dapt And Mk0752, Exhibit Synergistic Anticancer Effects With Cisplatin And Docetaxel In 2d And 3d Models Of Breast Cancer, Kübra Telli̇, Johannes Gubat, Padraig D'Arcy, Özden Yalçin Özuysal
Turkish Journal of Biology
Background/aim: Breast cancer remains a major malignancy among women, and severe side effects and the development of acquired drug resistance frequently hinder current therapeutic strategies. The Notch signaling pathway, a key regulator of cell fate, is commonly dysregulated in breast cancer and associated with poor prognosis. Gamma-secretase inhibitors (GSIs) block Notch receptor activation and have shown potential anticancer efficacy. This study aimed to investigate the synergistic activity of two commonly used GSIs, DAPT and MK0752, combined with docetaxel or cisplatin in both 2D and 3D breast cancer models.Materials and methods: Triple-negative, highly metastatic MDA-MB-231 and ER+/PR+ MCF-7 breast cancer cell …
Study On The Role Of Shenfu Injection In Mediating Ferroptosis Through The Akt/Gsk-3Β/Nrf2 Pathway In Yang-Deficient Chronic Heart Failure, Xiaojie Chen, Jiayun Guo, Bing Lin, Huamin Wang, Ziyu Lu, Bayi Liu
Study On The Role Of Shenfu Injection In Mediating Ferroptosis Through The Akt/Gsk-3Β/Nrf2 Pathway In Yang-Deficient Chronic Heart Failure, Xiaojie Chen, Jiayun Guo, Bing Lin, Huamin Wang, Ziyu Lu, Bayi Liu
Turkish Journal of Biology
Background/aim: The present study investigates the role of Shenfu injection in the treatment of yang-deficient chronic heart failure (CHF). Materials and methods: Sprague-Dawley (SD) rats were modeled for yang-deficient CHF by abdominal aortic coarctation. Echocardiography was performed to detect changes in cardiac function, and serum N-terminal B-type natriuretic peptide proteins (NT-proBNP), cardiac troponin I (cTnI), and ferroptosis-related factors were measured using ELISA kits. Pathological changes in cardiac tissues were observed through hematoxylin-eosin (HE) and Masson’ trichrome staining, cardiomyocyte apoptosis was measured by TUNEL staining, and reactive oxygen species (ROS) production was determined through dihydroethidium (DHE) staining. The expression of nuclear …
Identification Of Epigenetic Monotherapy Candidates In Taxane-Resistant Crpc, Buse Cevatemre, İpek Bulut, Ezgi̇ Karyemez, Ceyda Açilan
Identification Of Epigenetic Monotherapy Candidates In Taxane-Resistant Crpc, Buse Cevatemre, İpek Bulut, Ezgi̇ Karyemez, Ceyda Açilan
Turkish Journal of Biology
Background/aim: Taxane resistance remains a significant challenge in the effective treatment of castration-resistant prostate cancer (CRPC). Given the association of epigenetic regulation with chemotherapy resistance and cancer progression, this study aims to identify epigenetic vulnerabilities in two CRPC cell lines (DU145 and 22Rv1) established as resistant to two different taxanes, docetaxel (Dtx) and cabazitaxel (Cbz), using a small-molecule screening approach. Materials and methods: A small-molecule library targeting epigenetic regulators, including histone deacetylases (HDAC), histone methyltransferases, histone demethylases, bromodomain proteins, deoxyribonucleic acid methyltransferases, protein arginine deiminase, and histone acetyltransferase was utilized. Drug screening was performed on parental and taxane-resistant CRPC cell …
In Vitro Antibiofilm Activity Of Tyrosol Against Single And Dual-Species Biofilms Of Candida Tropicalis And Streptococcus Mutans, Zarifeh Adampour, Betül Yilmaz Öztürk, Bükay Yeni̇ce Gürsu, İlknur Dağ
In Vitro Antibiofilm Activity Of Tyrosol Against Single And Dual-Species Biofilms Of Candida Tropicalis And Streptococcus Mutans, Zarifeh Adampour, Betül Yilmaz Öztürk, Bükay Yeni̇ce Gürsu, İlknur Dağ
Turkish Journal of Biology
Background/aim: The cross-kingdom biofilm structure formed by Candida tropicalis and Streptococcus mutans may increase caries formation. The aim of this study was to evaluate the in vitro effect of the exogenous tyrosol on single- and dual-species biofilms as well as planktonic cultures formed by C. tropicalis and S. mutans. Materials and methods: The antimicrobial efficacy of tyrosol was evaluated through broth microdilution, colony-forming unit (CFU) enumeration, and XTT reduction tests to assess cell viability and metabolic activity. Transmission electron microscopy (TEM) was used to examine ultrastructural changes in planktonic cells. Biofilm dynamics were visualized via scanning electron microscopy (SEM) and …
Eucommia Ulmoides Extract Attenuates Oxidative Stress And Promotes Melanogenesis Via Wnt/Β-Catenin Signaling In B16 Cells And Mice, Xiaojin Liu, Yaqian Qiu, Xiaobing Lv, Lei Chang, Tiancheng Ji, Yefan Gu, Shuyue Chen
Eucommia Ulmoides Extract Attenuates Oxidative Stress And Promotes Melanogenesis Via Wnt/Β-Catenin Signaling In B16 Cells And Mice, Xiaojin Liu, Yaqian Qiu, Xiaobing Lv, Lei Chang, Tiancheng Ji, Yefan Gu, Shuyue Chen
Turkish Journal of Biology
Background/aim: Oxidative stress is a major contributor to melanocyte dysfunction and hair graying by impairing key signaling pathways. Eucommia ulmoides bark extract (EUE), rich in antioxidant phytochemicals, has shown potential in combating oxidative damage. This study investigated the protective and promelanogenic effects of EUE under hydrogen peroxide (H₂O₂)-induced oxidative stress, with a focus on the Wnt/β-catenin signaling pathway. Materials and methods: An oxidative stress model was established using B16 cells and a C57BL/6 mouse hair follicle model. Results: EUE significantly improved melanocyte survival and reduced intracellular reactive oxygen species (ROS). Mechanistically, EUE activated the Wnt/β-catenin pathway, leading to upregulation of …