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Full-Text Articles in Entire DC Network
Pyridine Substituted Bodipys: Synthesis, Characterization And Cholinesterease,α-Glucosidase Inhibitory, Dna Hydrolytic Cleavage Effects, Burak Barut, Hüseyi̇n Baş, Zekeri̇ya Biyiklioğlu
Pyridine Substituted Bodipys: Synthesis, Characterization And Cholinesterease,α-Glucosidase Inhibitory, Dna Hydrolytic Cleavage Effects, Burak Barut, Hüseyi̇n Baş, Zekeri̇ya Biyiklioğlu
Turkish Journal of Chemistry
In this study, the synthesis of new monostyryl (BDPY-2) and distyryl BODIPY dyes (BDPY-4, BDPY-5) containing pyridine groups has been reported for the first time. The acetylcholinesterase from Electrophorus electricus (AChE), butyrylcholinesterase from equine serum (BuChE), α-glucosidase from Saccharomyces cerevisiae and DNA hydrolytic cleavage actions of BDPY-2, BDPY-4, BDPY- 5 were investigated using various techniques. The results indicated that the compounds had varying inhibition properties against AChE, BuChE, and α-glucosidase. BDPY-4 was the most potent compound on AChE with IC50 of 54.78 ± 4.51 μM, and Lineweaver-Burk plots indicated that the compound is bound to a site other than the …
Supramolecular Solvents: A Review Of A Modern Innovation In Liquid-Phase Microextraction Technique, Muhammad Saqaf Jagirani, Mustafa Soylak
Supramolecular Solvents: A Review Of A Modern Innovation In Liquid-Phase Microextraction Technique, Muhammad Saqaf Jagirani, Mustafa Soylak
Turkish Journal of Chemistry
Supramolecular solvents (SUPRASs) have rapidly gained more attention as a potential substitute to organic solvents in the sample preparation and preconcentration process. The essential properties of SUPRAS solvents (e.g., multiple binding sites, different polarity microenvironments, the opportunity to tailor their properties, etc.) these qualities offer numerous opportunities to advance innovative sample preparation and pretreatment platforms compared to the traditional solvents. Among these qualities, certain importance is placed on theoretical and practical knowledge. That has assisted in making significant developments in SUPRAS that advance our understanding of the processes behind SUPRA'S formation. The SUPRA-solute interactions that drive extractions are explored in …
Novel Vic-Dioximes: Synthesis, Structure Characterization, And Antimicrobial Activity Evaluation, Dumitru Ureche, Ion Bulhac, Alexandru Ciocarlan, Daniel Roshca, Lucian Lupascu, Paulina Bourosh
Novel Vic-Dioximes: Synthesis, Structure Characterization, And Antimicrobial Activity Evaluation, Dumitru Ureche, Ion Bulhac, Alexandru Ciocarlan, Daniel Roshca, Lucian Lupascu, Paulina Bourosh
Turkish Journal of Chemistry
The vic-dioximes are compounds with various industrial uses and scientific applications. Many coordination compounds have been synthesized based on vic-dioximes. This study presents the synthesis and full characterization of two vic-dioximes based on dichloroglyoxime, p-aminobenzoic acid, and p-aminotoluene. Their structures were proved by IR, 1H, 13C and 15N NMR spectral analysis, and single crystal X-ray diffraction. One of the reported vic-dioximes, bis(di-p-aminotoluene)glyoxime mono-p-aminotoluene trihydrate showed good to moderate antimicrobial activity against both nonpathogenic gram-positive and gram-negative bacteria (Bacillus subtilis and Pseudomonas fluorescens), phytopathogenic (Xanthomonas campestris, Erwinia amylovora, E. carotovora) and the fungi (Candida utilis and Saccharomyces cerevisiae) at MIC - …
Preparation And Characterization Of Nano Mno-Cals As A Green Catalyst For Oxidation Of Styrene, Mahdi Arian, Hoda Mollabagher, Salman Taheri, Ali Zamanian, Seyed Amir Hossein Seyed Mousavi
Preparation And Characterization Of Nano Mno-Cals As A Green Catalyst For Oxidation Of Styrene, Mahdi Arian, Hoda Mollabagher, Salman Taheri, Ali Zamanian, Seyed Amir Hossein Seyed Mousavi
Turkish Journal of Chemistry
Hydrophilic nano MnO is shown to have significant stability in aqueous media for oxidation of styrene. Different catalysts have been used to synthesis styrene oxide, but MnO-CaL is considered the efficient and selective catalyst to produce styrene oxide. In general, this paper reported especial strategy for synthesis of novel nano MnO that stabilized with oleic acid in chloroform and changing nature of its stabilizer by exchanging oleic acid with lignosulfunate and displays its catalytic activity towards selective oxidation of styrene. The catalyst has shown good selectivity in oxidation of styrene by changing temperature. Finding the optimal conditions for reaction and …
A Four-Component Modified Biginelli Reaction: A Novel Approach For C-2 Functionalizeddihydropyrimidines, Harsha Narkhede, Avinash Dhake, Vaidhyanathan Balasubramaniyan
A Four-Component Modified Biginelli Reaction: A Novel Approach For C-2 Functionalizeddihydropyrimidines, Harsha Narkhede, Avinash Dhake, Vaidhyanathan Balasubramaniyan
Turkish Journal of Chemistry
A novel four component modified Biginelli reaction for the synthesis of C-2 functionalized dihydropyrimidines has been established. The approach uses assembly of less explored acetyl acetone with aromatic aldehyde, thiourea, and dimethyl sulphate to construct a novel 5-acetyl 2-methylthio dihydropyrimidine system, which works as an efficient well-designed intermediate for generating C-2 modified Biginelli libraries with nitrogen nucleophiles. Phenyl hydrazine, semicarbazide, and aryl semicarbazides are successfully used as N-nucleophiles to generate C-2 functionalized dihydropyrimidine derivatives, which fulfil the demands of active pharmacophore. Time economy, step economy, and a single pot reaction with moderate to excellent yield are the major advantages of …
Synthesis Of 7,12-Bis(4-(Di(1h-Pyrrol-2-Yl)Methyl)Phenyl)Benzo[K]Fluoranthene From Anew Dialdehyde As A Novel Fluorometric Bis-Dipyrromethane Derivative, Faride Ranjbari, Salar Hemmati, Mohammad Reza Rashidi
Synthesis Of 7,12-Bis(4-(Di(1h-Pyrrol-2-Yl)Methyl)Phenyl)Benzo[K]Fluoranthene From Anew Dialdehyde As A Novel Fluorometric Bis-Dipyrromethane Derivative, Faride Ranjbari, Salar Hemmati, Mohammad Reza Rashidi
Turkish Journal of Chemistry
Dipyrromethanes are useful mediator structures which can be used as a part of other molecules such as bis-porphyrins and their derivations. Various methods have been developed for their synthesis. This study presents the synthesis of a new bis- dipyrromethane, 7,12-bis(4-(di(1H-pyrrol-2-yl)methyl)phenyl)benzo[k]fluoranthene, using the Lewis acid catalyzed reaction between a new dialdehyde and pyrrole at room temperature. The UV spectroscopic and fluorometric properties of the final product and precursors were determined. The newly synthesized product with desirable UV spectroscopic and fluorometric properties has the potential to be applied as a part of bisporphyrins or it can be used for other purposes in …
Investigation Of Olea Ferruginea Roylebark Extracts For Potential In Vitroantidiabetic And Anticancer Effects, Samra Liaqat, Muhammad Islam, Hamid Saeed, Mehwish Iqtedar, Azra Mehmood
Investigation Of Olea Ferruginea Roylebark Extracts For Potential In Vitroantidiabetic And Anticancer Effects, Samra Liaqat, Muhammad Islam, Hamid Saeed, Mehwish Iqtedar, Azra Mehmood
Turkish Journal of Chemistry
This study was conducted to investigate the physicochemical, phytochemical, in vitro antidiabetic and anticancer potential of Olea ferruginea R bark. After extraction using Soxhlet, in vitro antidiabetic and cytotoxic activity on human hepatocellular carcinoma (HepG2) cells was assessed by nonenzymatic glycosylation of hemoglobin assay, alpha-amylase inhibition assay, glucose uptake by yeast cells, and 3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide assay, respectively, and gene expression via real-time polymerase chain reaction. Primary and secondary metabolites were present in the extractants; polyphenols (35.61 ± 0.03) and flavonoids (64.33 ± 0.35) in the chloroform; and polysaccharides in the ethanol (268.75 ± 0.34), and glycosaponins (78.01 ± …
New Chlorogenic Acid Derivatives And Triterpenoids From Scorzonera Aucheriana, İshak Eri̇k, Kami̇l Çoşkunçelebi̇, Serdar Makbul, Nuretti̇n Yayli
New Chlorogenic Acid Derivatives And Triterpenoids From Scorzonera Aucheriana, İshak Eri̇k, Kami̇l Çoşkunçelebi̇, Serdar Makbul, Nuretti̇n Yayli
Turkish Journal of Chemistry
Chromatographic separation of n-hexane and ethyl acetate fraction of a crude methanol extract obtained from aerial parts of the Scorzonera aucheriana DC collected from Sivas province of Turkey yielded nine natural compounds; two new 3-caffeoyl-quinic acid analogs (1-2), one new taraxasterol oleate (3), and six known triterpenoids taraxasterol (4), taraxasterol acetate (5), ptiloepoxide (6), lupeol (7), lupeol acetate (8), and β-sitosterol (9) were characterized. The structures of the isolated compounds were elucidated on the basis of NMR (1H, 13C, COSY, HMBC, HSQC, and TOCSY), UV, FT-IR and LC-Q-TOF-MS spectrometric data.
Co2 Hydrogenation To Methanol And Dimethyl Ether At Atmospheric Pressure Using Cu-Ho-Ga/Γ-Al2o3 And Cu-Ho-Ga/Zsm-5: Experimental Study And Thermodynamic Analysis, Cansu Tuygun, Bahar İpek
Co2 Hydrogenation To Methanol And Dimethyl Ether At Atmospheric Pressure Using Cu-Ho-Ga/Γ-Al2o3 And Cu-Ho-Ga/Zsm-5: Experimental Study And Thermodynamic Analysis, Cansu Tuygun, Bahar İpek
Turkish Journal of Chemistry
CO2 valorization through chemical reactions attracts significant attention due to the mitigation of greenhouse gas effects. This article covers the catalytic hydrogenation of CO2 to methanol and dimethyl ether using Cu-Ho-Ga containing ZSM-5 and γ-Al2O3 at atmospheric pressure and at temperatures of 210 °C and 260 °C using a CO2:H2 feed ratio of 1:3 and 1:9. In addition, the thermodynamic limitations of methanol and DME formation from CO2 was investigated at a temperature range of 100?400 °C. Cu-Ho-Ga/γ-Al2O3 catalyst shows the highest formation rate of methanol (90.3 μmolCH3OH/gcat/h ) and DME (13.2 μmolDME/gcat/h) as well as the highest selectivity towards …
Microwave Assisted, Sequential Two-Step, One-Pot Synthesis Of Novel Imidazo[1,2-A]Pyrimidine Containing Tri/Tetrasubstituted Imidazole Derivatives, Tuğba Güngör
Turkish Journal of Chemistry
A series of novel imidazo[1,2-a]pyrimidine containing tri/tetrasubstituted imidazole derivatives (1-10) has been synthesized via sequential two-step, one-pot, multicomponent reaction using imidazo[1,2-a]pyrimidine-2-carbaldehyde, benzil, primary amines, and ammonium acetate catalyzed by p-toluenesulfonic acid under microwave-assisted conditions. The results showed that target compounds can be obtained from a wide range of primary amines bearing different functional groups with moderate to good yields (46%-80%) under optimum reaction conditions. This method provides a green protocol for imidazo[1,2-a]pyrimidine containing tri/ tetrasubstituted imidazole derivatives due to ethyl alcohol as a green solvent, microwave irradiation as a greener heating method and one-pot multicomponent reaction as a green technique. …
Spectrophotometric Analysis Of Stability Of Gold Nanoparticles During Catalytic Reduction Of 4-Nitrophenol, Farhat Saira, Samia Saleemi, Humaira Razzaq, Rumana Qureshi
Spectrophotometric Analysis Of Stability Of Gold Nanoparticles During Catalytic Reduction Of 4-Nitrophenol, Farhat Saira, Samia Saleemi, Humaira Razzaq, Rumana Qureshi
Turkish Journal of Chemistry
Spectrophotometric monitoring of 4-nitrophenol (4-NP) reduction by sodium borohydride (NaBH4) using gold nanoparticles (GNPs) as a catalyst has been extensively studied, but the stability of GNPs in terms of change in the surface plasmon resonance (SPR) at different temperatures has not been explored. In the present investigation, our aim was to evaluate the SPR stability of GNPs as a catalyst during the reduction of 4-NP at different elevated temperatures (i.e. 30-60 °C) and sodium borohydride concentrations. Sensitivity of this degradation process toward concentration of GNPs at a range of temperatures is also evaluated. The spectrophotometric results reveal that up to …
Cytotoxic And Apoptotic Potential Of Some Coumarin And 2-Amino-3-Carbonitrile Selenophene Derivatives In Prostate Cancer, Meti̇n Yildirim, Mehmet Erşatir, Badel Arslan, Eli̇fe Sultan Gi̇ray
Cytotoxic And Apoptotic Potential Of Some Coumarin And 2-Amino-3-Carbonitrile Selenophene Derivatives In Prostate Cancer, Meti̇n Yildirim, Mehmet Erşatir, Badel Arslan, Eli̇fe Sultan Gi̇ray
Turkish Journal of Chemistry
3-acetyl coumarin derivatives (1a-d) are formed as a result of condensation of salicylaldehyde derivatives and ethyl acetoacetate and were converted into coumarin-selenophene hybrid compounds (2a-d) in the basic medium by modified Gewald reaction in the presence of malononitrile and selenium. Products are characterized by nuclear magnetic resonance (NMR). The prepared compounds are screened for their anticancer activity against DU-145 cell line. In addition, selected target compounds are evaluated for apoptosis and oxidative stress on DU-145 (prostate carcinoma) cell lines.
4,4'-Trimethylenedipiperidine As A Nitrogen Heterocycle Solvent And/Or Catalyst: Liquid Phase Tandem Knoevenagel-Michael Condensation, Lia Zaharani, Nader Ghaffari Khaligh, Hayede Gorjian, Mohd Rafie Johan
4,4'-Trimethylenedipiperidine As A Nitrogen Heterocycle Solvent And/Or Catalyst: Liquid Phase Tandem Knoevenagel-Michael Condensation, Lia Zaharani, Nader Ghaffari Khaligh, Hayede Gorjian, Mohd Rafie Johan
Turkish Journal of Chemistry
Liquid phase tandem Knoevenagel-Michael condensation of various aromatic and heteroaromatic aldehydes with barbituric acid or 2-thiobarbituric acid and malononitrile was studied in a one-pot three-component reaction. For the first time, TMDP was employed as a safe and efficient solvent and/or catalyst in the liquid and aqueous ethanol medium, respectively, for the practical and eco-friendly Knoevenagel-Michael condensation. The reactions were carried out by using greener procedures, including a) the use of TMDP as an N-heterocycle organocatalyst in a green medium including water and ethanol (1:1 v/v) at reflux temperature, and b) the use of TMDP as a dual solvent-catalyst at 65 …
A New Electrochemical Impedance Biosensor Based On Aromatic Thiol For Alpha-1 Antitrypsin Determination, Hülya Yağar, Hakki Mevlüt Özcan, Osman Mehmet
A New Electrochemical Impedance Biosensor Based On Aromatic Thiol For Alpha-1 Antitrypsin Determination, Hülya Yağar, Hakki Mevlüt Özcan, Osman Mehmet
Turkish Journal of Chemistry
Alpha-1 antitrypsin (A1AT) is one of the acute phase proteins which are synthesized in the liver. A1AT inhibits the activity of many proteases, but its main task is to protect the lungs from the attack of neutrophil elastase. In an autosomal hereditary disease known as alpha-1 antitrypsin deficiency, the A1AT level in blood serum decreases, increasing the risk of developing emphysema, liver apoptosis, and liver cancer. Thus, the detection of A1AT concentration in blood serum is very important. In this study, an impedimetric biosensor was developed, forming an SAM (self-assembled monolayer) with 4-mercaptophenylacetic acid (4MPA) on the surface of the …
The Effect Of H$_{2}$O On The Sulfation Of Havelock Limestone Under Oxy-Fuel Conditions In Athermogravimetric Analyser, Murat Varol, Edward John Anthony, Arturo Macchi
The Effect Of H$_{2}$O On The Sulfation Of Havelock Limestone Under Oxy-Fuel Conditions In Athermogravimetric Analyser, Murat Varol, Edward John Anthony, Arturo Macchi
Turkish Journal of Chemistry
A gas mixture representing oxy-fuel combustion conditions was employed in a thermogravimetric analyser to determine the effect of water vapor and SO$_{2}$ concentration on limestone sulfation kinetics over the temperature range of 800 to 920 °C. Here, experiments used small samples of particles (4 mg), with small particle sizes (d$_{p}$ < 38 μm) and large gas flow rates (120 mL/min@ NTP) in order to minimize mass transfer interferences. The gas mixture contained 5000 ppm$_{v}$ SO$_{2}$, 2% O$_{2}$, and the H$_{2}$O content was changed from 0% to 25% with the balance CO$_{2}$. When water vapor was added to the gas mixture at lower temperatures (800-870 °C), the limestone SO$_{2}$ capture efficiency increased. However, as the temperature became higher, the enhancement in total conversion values decreased. As expected, Havelock limestone at higher temperatures (890 °C, 920 °C, and 950 °C) experienced indirect sulfation and reacted at a faster rate than for lower temperatures (800-870 °C) for direct sulfation over the first five minutes of reaction time. However, the total conversion of Havelock limestone for direct sulfation was generally greater than for indirect sulfation.
Development Of A Spiramycin Sensor Based On Adsorptive Stripping Linear Sweepvoltammetry And Its Application For The Determination Of Spiramycin In Chicken Eggsamples, Mustafa Ci̇ttan
Turkish Journal of Chemistry
Herein, an adsorptive stripping linear sweep voltammetric technique was described to determine spiramycin, a macrolide antibiotic, using a carboxylic multiwalled glassy carbon electrode modified with carbon nanotubes. The main principle of the analytical methodology proposed was based on the preconcentration of spiramycin by open-circuit accumulation of the macrolide onto the modified electrode surface. As a result of the adsorption affinity of spiramycin to the modified surface, the sensitivity of the glassy carbon electrode was significantly increased for the determination of spiramycin. The electrochemical behavior of spiramycin was evaluated by cyclic voltammetry and the irreversible anodic peak observed was measured as …
Synthesis Of Some Nh- And Nh,S- Substituted 1,4-Quinones, Ayşeci̇k Kaçmaz
Synthesis Of Some Nh- And Nh,S- Substituted 1,4-Quinones, Ayşeci̇k Kaçmaz
Turkish Journal of Chemistry
A series of NH-substituted-1,4-quinones, possessing one, two, three or not chlorine, were synthesized by the reaction between different quinones (p-chloranil (1), p-toluquinone (2), or 2,3-dichloro-1,4-naphthoquinone (3)) and (-)-cis-myrtanylamine (5) via nucleophilic reactions. Moreover, 2-bromo-1,4-naphthoquinone (4) was reacted with 2-(methylthio)ethylamine (11) to produce aminosubstituted naphthoquinones (12 and 13), bearing with bromine and not bromine. In addition, 2-bromo-1,4-naphthoquinone (4) was reacted with 4?-aminodibenzo-18-crown-6 (14) and 4'-aminobenzo-18-crown-6 (16) to yield crown-containing 1,4-naphthoquinones (15 and 17), respectively. New compounds were characterized, providing 1H NMR, 13C NMR, FTIR, MS-ESI, UV/Vis and elemental analysis.
Synthesis, Characterization And Catalytic Properties Of Cationic N-Heterocyclic Carbene Silver Complexes, Deni̇z Demi̇r Atli
Synthesis, Characterization And Catalytic Properties Of Cationic N-Heterocyclic Carbene Silver Complexes, Deni̇z Demi̇r Atli
Turkish Journal of Chemistry
Three new dibenzimidazolium salts bridged by 2-methylenepropane-1,3-diyl group were synthesized. Their dinuclear N-heterocyclic carbene Ag(I) complexes were prepared by the reactions of these salts with Ag2O. The structures of the synthesized compounds were defined by nuclear magnetic resonance (NMR), Fourier-transform infrared spectroscopy (FT-IR), elemental analysis, and LC-MSMS (for complexes) techniques. Stability of the silver complexes was confirmed by 1H NMR spectroscopy. Catalytic activities of Ag(I) compounds were tested for three-component coupling reaction of some aldehydes, amines, and phenylacetylene.
Synthesis, Characterization, And Biological Evaluation Of New Copper Complexes Ofnaphthyl Pyrazole Ligands, Melek Hinis, Kuldip Singh, Demet Erdönmez, Ayfer Menteş
Synthesis, Characterization, And Biological Evaluation Of New Copper Complexes Ofnaphthyl Pyrazole Ligands, Melek Hinis, Kuldip Singh, Demet Erdönmez, Ayfer Menteş
Turkish Journal of Chemistry
Two naphthalene pyrazole ligands were synthesized using KOH/DMSO and Cu catalyst and characterized with FT-IR, ESIMS, 1H, and 13C NMR spectroscopies. The crystal structures of 1-(2-methylnaphthalen-1-yl)-1H-pyrazole (MeNap-Pz) ligand have been determined with X-ray crystal structure analysis. Reaction of the ligands with Cu(NO3)2x3.5H2O gave two new complexes and characterized with magnetic susceptibility, molar conductance, FT-IR, LCMS-MS, ICP-OES, NMR, thermogravimetric analysis, and ESR spectra. The spectral data of the ligands are coordinated to the metal ion through the nitrogen atoms of the pyrazole ring. Consequently, it has been determined that [Cu(MeNap-Pz)2 (NO3)]NO3.2H2O complex showed square planar geometry and [Cu(NapMe-Pz)2(NO3)2].H2O complex showed octahedral …
Synthesis, Spectral Characterization, And Biological Studies Of 3,5-Disubstituted- 1,3,4-Oxadiazole-2(3h)-Thione Derivatives, Tuğçe Özyazici, Fi̇kretti̇n Şahi̇n, Meri̇ç Köksal Akkoç
Synthesis, Spectral Characterization, And Biological Studies Of 3,5-Disubstituted- 1,3,4-Oxadiazole-2(3h)-Thione Derivatives, Tuğçe Özyazici, Fi̇kretti̇n Şahi̇n, Meri̇ç Köksal Akkoç
Turkish Journal of Chemistry
The reaction of 3,4-dichlorophenyl-1,3,4-oxadiazole-2(3H)-thione with piperidine derivatives via Mannich reaction was used to generate eleven novel compounds in moderate to good yields. Synthesized molecules were characterized according to their structure with 1H NMR, 13C NMR and FT-IR spectral foundations, which were compatible with literature informations. Antimicrobial activity and cytotoxicity studies were done by disc diffusion and NCI-60 sulphordamine B assay methods. The antimicrobial test results revealed that synthesized compounds have better activity against gram-positive species than gram-negative ones. A total analysis of the antibacterial, antifungal, and antiyeast activity revealed that newly synthesized compounds were really active against Bacillus cereus, Bacillus …
Novel Mannich Bases With Strong Carbonic Anhydrases And Acetylcholinesterase Inhibition Effects: 3-(Aminomethyl)-6-{3-[4-(Trifluoromethyl)Phenyl]Acryloyl}-2(3h)- Benzoxazolones, Si̇nan Bi̇lgi̇ner, Bariş Anil, Mehmet Koca, Yeli̇z Demi̇r, İlhami̇ Gülçi̇n
Novel Mannich Bases With Strong Carbonic Anhydrases And Acetylcholinesterase Inhibition Effects: 3-(Aminomethyl)-6-{3-[4-(Trifluoromethyl)Phenyl]Acryloyl}-2(3h)- Benzoxazolones, Si̇nan Bi̇lgi̇ner, Bariş Anil, Mehmet Koca, Yeli̇z Demi̇r, İlhami̇ Gülçi̇n
Turkish Journal of Chemistry
In this study, a new series of Mannich bases, 3-(aminomethyl)-6-{3-[4-(trifluoromethyl)phenyl]acryloyl}-2(3H)- benzoxazolones (1a-g), were synthesized by the Mannich reaction. Inhibitory effects of the newly synthesized compounds towards carbonic anhydrases (CAs) and acetylcholinesterase (AChE) enzymes were evaluated to find out new potential drug candidate compounds. According to the inhibitory activity results, Ki values of the compounds 1 and 1a-g were in the range of 12.3 ± 1.2 to 154.0 ± 9.3 nM against hCA I, and they were in the range of 8.6 ± 1.9 to 41.0 ± 5.5 nM against hCA II. Ki values of acetazolamide (AZA) that was used as …
The Impact Of Chilling On Selected Attributes Of The Blowfly, Calliphora Vicina(Robineau-Desvoidy, 1830) (Diptera: Calliphoridae), Under Laboratory Conditions, Meltem Kökdener, Nevran Eylem Akman Gündüz, Ünal Zeybekoğlu
The Impact Of Chilling On Selected Attributes Of The Blowfly, Calliphora Vicina(Robineau-Desvoidy, 1830) (Diptera: Calliphoridae), Under Laboratory Conditions, Meltem Kökdener, Nevran Eylem Akman Gündüz, Ünal Zeybekoğlu
Turkish Journal of Zoology
The purpose of this study was to evaluate the effects of four different chilling periods, varying from 24 to 120 h, on the mean survival rate, larval and pupal development durations and the pupal and adult weight of Calliphora vicina (Robineau-Desvoidy) (Diptera: Calliphoridae) under laboratory conditions at 4 ºC in 2018 at Ondokuz Mayıs University. Chilling reduced the survival rate of the pupae of all developmental stages. The adult eclosion rate of first instar larvae and pupae was lower, especially after 72 and 120 h chilling periods, but it increased for the second instar, third instar and postfeeding larvae with …
First Report On Mild Insecticide Resistance In Newly Established Aegean Aedes Albopictus Populations Of Turkey, Sare İlknur Yavaşoğlu
First Report On Mild Insecticide Resistance In Newly Established Aegean Aedes Albopictus Populations Of Turkey, Sare İlknur Yavaşoğlu
Turkish Journal of Zoology
The invasive nature of Aedes albopictus, a competent vector of dengue, zika, yellow fever, and chikungunya viruses, has spread to many parts of the world. To date, there have been no report regarding the insecticide resistance status of Aedes albopictus populations along the Aegean coasts of Turkey. This study aims to confirm the occurrence of Aedes albopictus populations in the Aegean region of Turkey and test their susceptibility against different insecticide classes. Bioassay for susceptibility to Dikloro difenil trikloroetan (DDT) (4%), propoxur (0.1%), fenitrothion (1%), bendiocarb (0.1%), permethrin (0.75%), and deltamethrin (0.05%) of each population was assessed through the World …
A Standardised Analytical Framework For Sampling Fish Communities: Relevance Toturkish Riverine Ecosystems, Lorenzo Vilizzi, Ali̇ Serhan Tarkan, Baran Yoğurtçuoğlu
A Standardised Analytical Framework For Sampling Fish Communities: Relevance Toturkish Riverine Ecosystems, Lorenzo Vilizzi, Ali̇ Serhan Tarkan, Baran Yoğurtçuoğlu
Turkish Journal of Zoology
Fish communities are important indicators of the health of riverine ecosystems. Fish monitoring for The Living Murray (TLM) initiative, one of Australia's most ambitious restoration undertakings for the degraded river-floodplain biota of the River Murray system (south-eastern Australia), was carried out annually from 2005 to 2011 across six 'Icon Sites', including the habitats and reaches therein. These spatial and temporal components of variation in fish community abundance and composition must be taken explicitly into account for consistent assessment of riverine ecosystem health. To address this requirement, a standardised analytical framework, consisting of a sampling design and appropriate statistical methods, is …
Morphology And Phylogeny Of A New Soil Ciliate, Colpodidium Zelihayildizi N. Sp. (Ciliophora, Nassophorea, Colpodidiidae), From Van, Turkey, İsmai̇l Yildiz
Morphology And Phylogeny Of A New Soil Ciliate, Colpodidium Zelihayildizi N. Sp. (Ciliophora, Nassophorea, Colpodidiidae), From Van, Turkey, İsmai̇l Yildiz
Turkish Journal of Zoology
new ciliate species Colpodidium zelihayildizae n. sp., which was discovered in a dry irrigation channel in Van (Turkey), was investigated morphologically using standard live and silver impregnation methods, and its SSU rRNA gene phylogeny was provided. This new species was characterized as follows: body size about 40-60 × 15-20 ?m in vivo, elongated ellipsoidal with flat or slightly concave ventral surface; the buccal cavity slightly below equatorial plane; macronucleus spherical or slightly elliptical, usually located in the last third of the cell; cortex distinctly furrowed in the anterior half; 19-22 somatic kineties, 4 postoral kineties; paroral membrane has 20 dikinetids; …
The Inhibition Of Src Kinase Suppresses The Production Of Matrix Metalloproteinases Infrom Synovial Fibroblasts And Inhibits Mapk And Stats Pathways, Demet Yalçin Kehri̇bar, Meti̇n Özgen, Servet Yolbaş, Ahmet Yildirim, Neşe Başak Türkmen, Ebru Önalan, Osman Çi̇ftçi̇, İbrahi̇m Hani̇fi̇ Özercan, Süleyman Serdar Koca
The Inhibition Of Src Kinase Suppresses The Production Of Matrix Metalloproteinases Infrom Synovial Fibroblasts And Inhibits Mapk And Stats Pathways, Demet Yalçin Kehri̇bar, Meti̇n Özgen, Servet Yolbaş, Ahmet Yildirim, Neşe Başak Türkmen, Ebru Önalan, Osman Çi̇ftçi̇, İbrahi̇m Hani̇fi̇ Özercan, Süleyman Serdar Koca
Turkish Journal of Medical Sciences
Background/aim: The purpose of this study was to investigate the antiarthritic potentials of the inhibition of Src kinase in vivo and in vitro settings. Materials and methods: Arthritis was induced by intradermal injection of chicken type II collagen combined with incomplete Freund's adjuvant (collagen induced arthritis [CIA] model) in Wistar albino rats. One day after the onset of arthritis, dasatinib, a potent Src kinase inhibitor, (5 mg/kg/day) was given via oral gavage. Tissue Src, Fyn, MAPK and STAT mRNA expressions were determined by real-time polymerase chain reaction. On the other hand, fibroblast like synoviocytes (FLSs) were harvested patients with rheumatoid …
Comparison Of The Effect Of Bipolar Coagulation And Fibrillar Structured Oxidizedcellulose On Formation Epidural Fibrosis In Rats, Eyüp Çeti̇n, Burak Eren, Feyza Karagöz Güzey, Azmi̇ Tufan, Abdurrahi̇m Taş, Mustafa Örnek, Bülent Uyanik, Tuğçe Çay
Comparison Of The Effect Of Bipolar Coagulation And Fibrillar Structured Oxidizedcellulose On Formation Epidural Fibrosis In Rats, Eyüp Çeti̇n, Burak Eren, Feyza Karagöz Güzey, Azmi̇ Tufan, Abdurrahi̇m Taş, Mustafa Örnek, Bülent Uyanik, Tuğçe Çay
Turkish Journal of Medical Sciences
Background/aim: Epidural fibrosis (EF) is a common cause of failed back surgery syndrome seen after spinal surgeries. The most frequent reason for the formation of EF is accumulated blood and its products in the operation zone. On the development of EF, the effect of bipolar coagulation and fibrillar oxidized cellulose, which are used frequently to control bleeding, was investigated. Materials and methods: In the study, 45 male Sprague Dawley rats were divided into three groups (control, fibrillar, and bipolar). Lumbar laminectomy was applied to all rats under sterile conditions. In the control group, the epidural area was washed with saline …
A Novel Marker Of Systemic Inflammation In Psoriasis And Related Comorbidities: Chitotriosidase, Bi̇lal İlanbey, Ömer Faruk Elmas, Eser Yildirim Sözmen, Ümran Günay, Abdullah Demi̇rbaş, Mustafa Atasoy, Ümi̇t Türsen, Torello Lotti̇
A Novel Marker Of Systemic Inflammation In Psoriasis And Related Comorbidities: Chitotriosidase, Bi̇lal İlanbey, Ömer Faruk Elmas, Eser Yildirim Sözmen, Ümran Günay, Abdullah Demi̇rbaş, Mustafa Atasoy, Ümi̇t Türsen, Torello Lotti̇
Turkish Journal of Medical Sciences
Background/aim: Chitotriosidase (ChT) is an enzyme secreted by activated macrophages and neutrophils in response to proinflammatory signals. There is growing evidence indicating that ChT activity reflects the systemic inflammatory status. This study aimed to investigate whether serum ChT activity increased in patients with psoriasis and related comorbidities. Materials and methods: This cross-sectional study included 53 (28 with associated comorbidities and 25 without comorbidities) patients with psoriasis and 52 healthy volunteers. All participants underwent laboratory investigations for serum ChT levels, complete blood count, erythrocyte sedimentation rate, C-reactive protein, and serum lipid levels. Results: The patients with psoriasis showed significantly higher levels …
Risk Of Autism Spectrum Disorder In Children With A History Of Hospitalization Forneonatal Jaundice, Gaffari̇ Tunç, Ayla Uzun Çi̇çek, Fati̇h Kiliçbay
Risk Of Autism Spectrum Disorder In Children With A History Of Hospitalization Forneonatal Jaundice, Gaffari̇ Tunç, Ayla Uzun Çi̇çek, Fati̇h Kiliçbay
Turkish Journal of Medical Sciences
Background/aim: Limited research has focused explicitly on the association between neonatal jaundice and autism spectrum disorder (ASD), and inconclusive evidence exists in the literature within this framework. This study aimed specifically to investigate whether neonatal jaundice is a potential risk factor for ASD and whether there is a connection between the types of neonatal jaundice and the severity of ASD. Materials and method: This study involved 119 children with ASD [90 males (75.6%), 29 females (24.4%), mean age: 45.39 ± 11.29 months] and 133 healthy controls [100 males (75.2%), 33 females (24.8%), mean age: 46.92 ± 11.42 months]. Psychiatric disorders …
Efficacy Of The In Vitro Splitting Of Human Preimplantation Embryos From Art Programs, Marjan Omidi, Mohammad Ali Khalili, Azam Agha-Rahimi, Stefania Nottola, Fatemeh Anbari, Azita Faramarzi, Maria Grazia Palmerini
Efficacy Of The In Vitro Splitting Of Human Preimplantation Embryos From Art Programs, Marjan Omidi, Mohammad Ali Khalili, Azam Agha-Rahimi, Stefania Nottola, Fatemeh Anbari, Azita Faramarzi, Maria Grazia Palmerini
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to evaluate the efficiency of in vitro embryo splitting (IES) procedures. We also assessed the quality of the blastocysts developed from embryos obtained from different sources. Materials and methods: Good quality embryos at 6-8-cell stages were categorized according to their fertilization sources: 1) frozenwarmed donated embryos, 2) chromosomally abnormal embryos, 3) parthenogenetic embryos, and 4) embryos derived from fertilization of in vitro matured oocytes (rescue IVM). After IES, splitting and developmental efficiency was assessed. Furthermore, the quality of the developed blastocysts was evaluated by Hoechst and propidium iodide (PI) staining. Results: The data …