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Expression Of Soluble, Active, Fluorescently Tagged Hephaestin In Cos And Cho Cell Lines, Eli̇f Si̇bel Aslan, Kenneth N. White, Basharut A. Syed, Kaila S. Srai, Robert W. Evans
Expression Of Soluble, Active, Fluorescently Tagged Hephaestin In Cos And Cho Cell Lines, Eli̇f Si̇bel Aslan, Kenneth N. White, Basharut A. Syed, Kaila S. Srai, Robert W. Evans
Turkish Journal of Biology
Hephaestin (Hp) is a trans-membrane protein, which plays a critical role in intestinal iron absorption. Hp was originally identified as the gene responsible for the phenotype of sex-linked anaemia in the sla mouse. The mutation in the sla protein causes accumulation of dietary iron in duodenal cells, causing severe microcytic hypochromic anaemia. Although mucosal uptake of dietary iron is normal, export from the duodenum is inhibited. Hp is homologous to ceruloplasmin (Cp), a member of the family of multi copper ferroxidases (MCFs) and possesses ferroxidase activity that facilitates iron release from the duodenum and load onto the serum iron transport …
Insecticidal Effect Of Diatomaceous Earth And Dolomite Powder Against Corn Weevilsitophilus Zeamais Motschulsky, 1855 (Coleoptera: Curculionidae), Alyssa Cristina Oliveira Freitas, Adriana Aparecida Sinopólis Gigliolli, Ronaldo Roberto Tait Caleffe Caleffe, Helio Conte
Insecticidal Effect Of Diatomaceous Earth And Dolomite Powder Against Corn Weevilsitophilus Zeamais Motschulsky, 1855 (Coleoptera: Curculionidae), Alyssa Cristina Oliveira Freitas, Adriana Aparecida Sinopólis Gigliolli, Ronaldo Roberto Tait Caleffe Caleffe, Helio Conte
Turkish Journal of Zoology
Sitophilus zeamais Motschulsky, 1855 (Coleoptera: Curculionidae) which develops inside the grain, is an aggressive pest of stored grains. Here, we evaluated the efficiency of diatomaceous earth (DE), Diatomita CI/325 CX, and dolomite (DOL), Dolomita Dr. Kanyo, against S. zeamais reared on corn under laboratory conditions and observed external alterations on treated insects using scanning electron microscopy (SEM). Insects treated with both DE and DOL were impregnated with particles on the body surface, and they showed 100% mortality after 10 days of exposure. Damages caused by inert dusts may have contributed to dehydration and desiccation, consequently, leading insects to death. Thus, …
Data-Driven Identification Of Chemopreventive Agents For Breast Cancer, Deni̇z Can Güven, Cemal Orhan, Kazi̇m Şahi̇n, Fatih Mehmet Uçkun
Data-Driven Identification Of Chemopreventive Agents For Breast Cancer, Deni̇z Can Güven, Cemal Orhan, Kazi̇m Şahi̇n, Fatih Mehmet Uçkun
Turkish Journal of Medical Sciences
Preclinical animal models of breast cancer provide the opportunity to identify chemopreventive drugs with single-agent activity as well as effective multi-modality regimens for primary as well as secondary prevention in high-risk persons. Our group has used the 7,12-dimethylbenz(a)anthracene (DMBA) mouse model of carcinogen-induced breast cancer to explore the clinical potential of two tyrosine kinase inhibitors and a nucleoside analog as chemopreventive agents. All three agents exhibited promising preclinical activity both as monotherapy and as components of combination therapy with the standard chemotherapy drug paclitaxel. The tumors developing despite chemoprevention were not only small and grew slowly, but they also displayed …
Effects Of Oral/Enteral Nutrition Alone Versus Plus Pantoprazole On Gastrointestinalbleeding In Critically Ill Patients With Low Risk Factor: A Multicenter, Randomizedcontrolled Trial, Kürşat Gündoğan, Emre Karakoc, Turgut Teke, Avşar Zerman, Ali̇ye Esmaoglu, Şahi̇n Temel, Muhammet Güven, Murat Sungur
Effects Of Oral/Enteral Nutrition Alone Versus Plus Pantoprazole On Gastrointestinalbleeding In Critically Ill Patients With Low Risk Factor: A Multicenter, Randomizedcontrolled Trial, Kürşat Gündoğan, Emre Karakoc, Turgut Teke, Avşar Zerman, Ali̇ye Esmaoglu, Şahi̇n Temel, Muhammet Güven, Murat Sungur
Turkish Journal of Medical Sciences
Background/aim: Critically ill patients are at risk of developing gastrointestinal (GI) bleeding due to stress causing mucosal damage. Aim of the study was to determine the effect of oral/enteral nutrition with or without concomitant pantoprazole on upper GI bleeding in low risk critically ill patients. Materials and methods: This was a prospective, randomized, open-label, multicenter study conducted with intensive care unit (ICU) patients receiving oral/enteral nutritional support. Patients were randomly assigned into two groups including intervention group (received oral/EN plus pantoprazole) and control group (received only oral/EN). Results: A total of 300 patients (intervention group: 152, control group: 148) participated …
Posterior Fossa Horns; A New Calvarial Finding Of Mucopolysaccharidoses With Well-Known Cranial Mri Features, Çağri Damar, Betül Emi̇ne Deri̇nkuyu, Muazzez Asburçe Bi̇ke Olgaç Kiliçkaya, Mehmet Öztürk, Çi̇ğdem Öztunali, Ayşe Gül Alimli, Öznur Leman Boyunaga, Murat Uçar, Fati̇h Süheyl Ezgü, Leyla Tümer, Alp Özgün Börcek, Ahmet Siğirci
Posterior Fossa Horns; A New Calvarial Finding Of Mucopolysaccharidoses With Well-Known Cranial Mri Features, Çağri Damar, Betül Emi̇ne Deri̇nkuyu, Muazzez Asburçe Bi̇ke Olgaç Kiliçkaya, Mehmet Öztürk, Çi̇ğdem Öztunali, Ayşe Gül Alimli, Öznur Leman Boyunaga, Murat Uçar, Fati̇h Süheyl Ezgü, Leyla Tümer, Alp Özgün Börcek, Ahmet Siğirci
Turkish Journal of Medical Sciences
Background/aim: Mucopolysaccharidoses (MPS) are a group of hereditary metabolic diseases. The aim of this study was to share the previously unreported calvarial finding of internal hypertrophy of the occipitomastoid sutures (IHOMS) together with some other well- known cranial MRI findings in this patient series. Materials and methods: A retrospective evaluation was conducted of 80 cranial MRIs of patients who had been diagnosed and followed up with MPS from 2008 to 2019 in our center. Of these patients, 11 had Hurler, 14 had Hunter, 24 had Sanfilippo, 15 had Morquio, 14 had Maroteaux-Lamy, and 2 had Sly disease. The cranial MRIs …
The Effect Of Baicalein On Wnt/Ss-Catenin Pathway And Mir-25 Expression In Saos-2 Osteosarcoma Cell Line, Esra Örenli̇li̇ Yaylagül, Celal Ülger
The Effect Of Baicalein On Wnt/Ss-Catenin Pathway And Mir-25 Expression In Saos-2 Osteosarcoma Cell Line, Esra Örenli̇li̇ Yaylagül, Celal Ülger
Turkish Journal of Medical Sciences
Background/aim: Osteosarcoma is the most common primary bone malignancy that occurs frequently in children and adolescents. Baicalein, a flavonoid that has attracted great attention in recent years with its strong antitumor activity, shows a wide range of biological and pharmaceutical effects.MicroRNAs have been found to be involved in many critical processes in cancers. This study aimed to investigate the effect of baicalein and miR-25 on Wnt/ß-catenin signaling pathway of osteosarcoma cell line Saos-2. Materials and methods: Cell viability was assessed, and qRT-PCR and Western blot were performed to study the effects of baicalein on expression of Wnt/ß-catenin signaling pathway-realted genes …
Baseline Characteristics Predicting Clinical Outcomes And Serious Adverse Events In Middle-Aged Hypertensive Women: A Subanalysis Of The Sprint In Women Aged, Volkan Aydin, Ahmet Akici, Si̇bel Sakarya, Mehmet Akman, Ali̇ Serdar Fak
Baseline Characteristics Predicting Clinical Outcomes And Serious Adverse Events In Middle-Aged Hypertensive Women: A Subanalysis Of The Sprint In Women Aged, Volkan Aydin, Ahmet Akici, Si̇bel Sakarya, Mehmet Akman, Ali̇ Serdar Fak
Turkish Journal of Medical Sciences
Background/aim: The predictability of clinical outcomes in hypertension in specific patient groups, especially underrepresented populations is the key to rational treatment. This study aimed to investigate the impact of baseline characteristics of
Effects Of Environmental Heterogeneity And Temporal Variation On Ecological Relationships Of Vegetation In A Seasonally Dry Tropical Forest In Brazil, Alisson Borges Miranda Santos, Nathalle Cristine Alencar Fagundes, Cleber Rodrigo Souza, Vinicius Andrade Maia, Wilder Bento Da Silva, Gabriela Gomes Pires De Paula, Felipe De Carvalho Araujo, Polyanne Coelho, Natália Aguiar-Campos, Diego Teixeira Girardelli, Jean Daniel Morel, Rubens Manoel Dos Santos
Effects Of Environmental Heterogeneity And Temporal Variation On Ecological Relationships Of Vegetation In A Seasonally Dry Tropical Forest In Brazil, Alisson Borges Miranda Santos, Nathalle Cristine Alencar Fagundes, Cleber Rodrigo Souza, Vinicius Andrade Maia, Wilder Bento Da Silva, Gabriela Gomes Pires De Paula, Felipe De Carvalho Araujo, Polyanne Coelho, Natália Aguiar-Campos, Diego Teixeira Girardelli, Jean Daniel Morel, Rubens Manoel Dos Santos
Turkish Journal of Botany
Species distribution patterns, community structure, and dynamics are determined on a small scale by soil and habitat heterogeneity. The aim of this work is to evaluate the temporal changes in composition and structure of a tree community, revealing the ecological drivers of the observed vegetation patterns. For 16 years (2000, 2005, 2010, and 2016) we monitored the temporal variations in structure and floristic composition of a semideciduous seasonal forest through 20 × 20 m2 (400 m2) plots, totaling 2.08 ha of sampled area encompassing Cambisol (0.4 ha), Oxysol (1.12 ha), and Nitosol (0.56 ha) soil classes. These tree communities were …
Enhanced Stress Tolerance In Transformed Ajuga Bracteosa Wall. Ex Benth. Regenerants By Upregulated Gene Expression Of Metabolic Pathways, Samina Rubnawaz, Waqas Kayani, Rashid Mahmood, Bushra Mirza
Enhanced Stress Tolerance In Transformed Ajuga Bracteosa Wall. Ex Benth. Regenerants By Upregulated Gene Expression Of Metabolic Pathways, Samina Rubnawaz, Waqas Kayani, Rashid Mahmood, Bushra Mirza
Turkish Journal of Botany
The rol oncogenes of Agrobacterium rhizogenes enhance the production of medicinally important compounds in plants and provide a first barrier against the overproduction of reactive oxygen species during biotic and abiotic stress. This study was designed to evaluate the expression of genes involved in biosynthetic pathways and their impact on metabolic contents and environmental stress tolerance in regenerated Ajuga bracteosa Wall. ex Benth. After successful transformation, real-time quantitative PCR confirmed the increased expression (1.94-6.59-fold) of HMGR, HDS, FDS, PAL, and TTG1 genes in transgenic lines. Furthermore, GC-MS coupled with principal component analysis revealed diverse concentrations of 97 metabolites in A. …
Assessment Of Genetic Gain And Its Simulation For Performance Traits In Sahiwal Cattle, Poonam Ratwan, Atish Kumar Chakravarty, Manoj Kumar
Assessment Of Genetic Gain And Its Simulation For Performance Traits In Sahiwal Cattle, Poonam Ratwan, Atish Kumar Chakravarty, Manoj Kumar
Turkish Journal of Veterinary & Animal Sciences
The study was conducted to estimate the expected genetic gain (ΔG) for first lactation performance traits in Sahiwal cattle as a result of direct selection of animals maintained at the ICAR-National Dairy Research Institute in India. Data pertaining to 305-day milk yield (305DMY), wet average (WA), and calving to first insemination interval (CFI) of the animals considering 13 counts of progenies/ sire were initially analyzed. The ΔG through direct selection was 43.68 kg/year, 0.13 kg/year, and 1.68 days/year for 305DMY, WA, and CFI, which was 1.97%, 1.65%, and 2.02% of herd average, respectively. In addition, ΔG was estimated by simulating …
Evaluation Of Animal Models For Genetic Analysis Of Growth Performance In Landlly Pigs, Snehasmita Panda, Gyanendra Kumar Gaur, Nihar Ranjan Sahoo, Sheikh Firdous Ahmad, Pruthviraj Devamma Ramachandrappa, Panch Kishor Bharti
Evaluation Of Animal Models For Genetic Analysis Of Growth Performance In Landlly Pigs, Snehasmita Panda, Gyanendra Kumar Gaur, Nihar Ranjan Sahoo, Sheikh Firdous Ahmad, Pruthviraj Devamma Ramachandrappa, Panch Kishor Bharti
Turkish Journal of Veterinary & Animal Sciences
Selection of the most appropriate animal model for the estimation of genetic parameters for body weight was carried out using restricted maximum likelihood (REML) procedure at birth and thereafter at 3, 6, and 8 weeks of age in Landlly pigs. Six different models were fitted for each trait; by inclusion or exclusion of maternal additive genetic effect, maternal permanent environmental effect, and covariance between direct and maternal additive genetic effects. Records on 1968 piglets, born in 4 parities of 131 gilts/sows, sired by 68 boars during a period of 5 years from 2014 to 2018 were used. In order to …
Evaluation Of Various Barley Processing Methods On Rumen Microbial Population,Histomorphometry, And Fermentation Characteristics In Fattening Lambs, Mohammad Hosseini Zangneh, Masihollah Forouzmand, Mokhtar Khajavi, Shima Hosseinifar, Reza Naghiha
Evaluation Of Various Barley Processing Methods On Rumen Microbial Population,Histomorphometry, And Fermentation Characteristics In Fattening Lambs, Mohammad Hosseini Zangneh, Masihollah Forouzmand, Mokhtar Khajavi, Shima Hosseinifar, Reza Naghiha
Turkish Journal of Veterinary & Animal Sciences
Barley deserves a top place in the farm for feeding livestock. It is irreplaceable by any other grain in sheep diets for producing capacious rumen microbial yields. The present study was conducted to investigate the effect of different methods of barley processing on a number of microbes, fermentation parameters, and the rumen tissue characteristics of fattening lambs. For this purpose, 20 fattening male lambs with a mean weight of 25 ± 1.1 kg were tested for 80 days based on a completely randomized design with four treatments (GRB: ground barley, SRB: steam-rolled barley, GEB: germinated barley, SOB: soaked barley) and …
Cover And Contents
Turkish Journal of Veterinary & Animal Sciences
No abstract provided.
Slaughter And Carcass Characteristics Of Kıvırcık, Karacabey Merino, Ramlıç, Germanblack-Head Mutton × Kıvırcık And Hampshire Down × Merino Crossbreed Lambs Rearedunder Intensive Conditions, Vasfi̇ye Kader Esen, Seli̇m Esen, Orhan Karadağ, Alper Önenç, Cengi̇z Elmaci
Slaughter And Carcass Characteristics Of Kıvırcık, Karacabey Merino, Ramlıç, Germanblack-Head Mutton × Kıvırcık And Hampshire Down × Merino Crossbreed Lambs Rearedunder Intensive Conditions, Vasfi̇ye Kader Esen, Seli̇m Esen, Orhan Karadağ, Alper Önenç, Cengi̇z Elmaci
Turkish Journal of Veterinary & Animal Sciences
This study aimed to determine the slaughter and carcass characteristics of five different meat-type lambs reared under intensive husbandry conditions. For this purpose, a total of 202 lambs-Kıvırcık (K, n = 51), Karacabey Merino (KM, n = 47), Ramlıç (R, n = 28), German Black-Head Mutton × Kıvırcık (GBK, n = 49), and Hampshire Down × Merino crossbreed (HM, n = 27)-were used to evaluate rearing performance. At the end of the rearing period, 10 male lambs of each breed were randomly selected to investigate slaughter and carcass characteristics. All lambs were housed in a single flock until the slaughtering …
Production And Egg Quality Traits Of Organic Hens In A Laying Period Under Commercialconditions In Turkey, Onur Saribaş, Umut Sami̇ Yamak
Production And Egg Quality Traits Of Organic Hens In A Laying Period Under Commercialconditions In Turkey, Onur Saribaş, Umut Sami̇ Yamak
Turkish Journal of Veterinary & Animal Sciences
The productive performance and egg quality traits of hens in an organic production system in Turkey were executed in this paper. A total of 6000 hens were reared in an organic system for 72 weeks. Two organic certified houses each with a capacity of 3000 hens were used in the study. Mean egg production during the laying period was 303 eggs per hen. Laying rate was 80.24% for 72 weeks, while mortality was 8.85%. The internal and external egg quality traits were determined between 25 and 72 weeks. Mean egg weight was 63.03 g and shell thickness was 0.35 mm. …
The Role Of Resveratrol On Mast Cell And Chymase And Tryptase Expression In Blunt-Chesttrauma-Induced Acute Lung Injury In Rats, Şeri̇fe Tütüncü, Aysun Çağlar Torun, Tuğrul Ertuğrul
The Role Of Resveratrol On Mast Cell And Chymase And Tryptase Expression In Blunt-Chesttrauma-Induced Acute Lung Injury In Rats, Şeri̇fe Tütüncü, Aysun Çağlar Torun, Tuğrul Ertuğrul
Turkish Journal of Veterinary & Animal Sciences
Acute lung injury is a clinical symptom that can cause morbidity, acute respiratory failure, and risk of developing pneumonia. Mast cells are found more commonly in places where antigens can enter the body, such as skin and respiratory and digestive systems, which enables them to be among the first groups of cell to act in the defense mechanism against foreign matter entry. Resveratrol is an active substance which is found in the structure of many plants and which can be used against pathogens due to its antimicrobial effect. The aim of our study is to show the degranulation and heterogeneity …
Effect Of Light-Emitting Diode (Led)-Based Colors On Production Performance Andwelfare Of Commercial Layers, Fazal Raziq, Jibran Hussain, Athar Mahmud, Khalid Javed
Effect Of Light-Emitting Diode (Led)-Based Colors On Production Performance Andwelfare Of Commercial Layers, Fazal Raziq, Jibran Hussain, Athar Mahmud, Khalid Javed
Turkish Journal of Veterinary & Animal Sciences
Artificial light, in terms of its intensity and color, is of significant importance for the performance of laying hens. In this study, the efforts were made to evaluate the effect of different light-emitting diode (LED)-based light colors on production performance, welfare, and egg quality attributes of Lohmann LSL lite hens in an open-sided house. For this, 200 commercial laying hens were distributed into 4 treatment groups, having 5 replicates of 10 birds each. The treatments included different LED colors, i.e. white, monochromatic green, monochromatic red, and dichromatic red?green. Green light significantly increased body weight as compared to other LED light …
Pathogenicity Of Aerobic Bacteria Isolated From Honeybees (Apis Mellifera) In Ordu Province, Emi̇ne Şeyma Boğ, Ömer Ertürk, Mustafa Yaman
Pathogenicity Of Aerobic Bacteria Isolated From Honeybees (Apis Mellifera) In Ordu Province, Emi̇ne Şeyma Boğ, Ömer Ertürk, Mustafa Yaman
Turkish Journal of Veterinary & Animal Sciences
The honeybee (Apis mellifera) is an important pollinator insect. Any pathogenic infection in this beneficial insect is undesirable. In this study, bacterial diversity in beehives was investigated to determine the potential of pathogenic bacteria in honeybees. To do this, bacterial isolations were carried out from dead and diseased adult bees collected from 9 districts in Ordu Province in Turkey.Twenty species of pathogenic bacteria, 18 of which were nonsporeforming Staphylococcus lentus, Klebsiella oxytoca, Citrobacter freundii, Leucanostoc mesenteroides ssp. cremoris, Kocuria rosea, Kocuria kristinae, Sphingomonas paucimobilis slashline, Burkholderia cepacia, Leucanostoc mesenteroides ssp. dextranicum,Hafnia alvei, Escherichia coli, Aeromonas salmonicida, Citrobacter braakii, Pantoea agglomerans, …
The Effects Of Thyme Oil And Black Cumin Oil In Broiler Feeding On Growth Performance, Intestinal Histomorphology, And Cecal Volatile Fatty Acids, Özlem Durna Aydin, Gülteki̇n Yildiz
The Effects Of Thyme Oil And Black Cumin Oil In Broiler Feeding On Growth Performance, Intestinal Histomorphology, And Cecal Volatile Fatty Acids, Özlem Durna Aydin, Gülteki̇n Yildiz
Turkish Journal of Veterinary & Animal Sciences
The aim of the study was to investigate the effects of thyme oil and black cumin oil that are added to broiler rations at certain ratios, on performance (body weight, body weight gain, feed intake, feed conversion ratio, mortality, European Production Efficiency Factor (EPEF), histomorphological parameters of jejunum and ileum, and cecal short-chain fatty acid (SCFA) concentrations. In the study, 216 male chicks (Ross 308) were randomly divided into 4 groups of 54 chicks each. Each group was divided into 9 subgroups of 6 chicks. The chicks were fed with corn, soya bean, and full-fat soybean-based rations for 42 days. …
Herbal Feed Additives Containing Tannins: Impact On In Vitro Fermentation And Methanemitigation From Total Mixed Ration, Manju Wadhwa, Prabh Kaur Sidhu, Mohinder Pal Singh Bakshi
Herbal Feed Additives Containing Tannins: Impact On In Vitro Fermentation And Methanemitigation From Total Mixed Ration, Manju Wadhwa, Prabh Kaur Sidhu, Mohinder Pal Singh Bakshi
Turkish Journal of Veterinary & Animal Sciences
Total mixed ration (TMR) containing roughage and concentrate mixture in a 65: 35 ratio on dry matter (DM) basis was supplemented with herbal feed additives [(HFAs); Acacia catechu (Katha), Areca catechu (Supari), and Acacia nilotica (Babul)] at 0-4% on DM basis to assess their impact on fermentation pattern and methane production by using in vitro gas production technique. Areca catechu had the highest (P < 0.01) concentration of condensed tannins (CTs), saponins, and vitamin C as compared to other HFAs. The net gas production (NGP), digestibility of NDF and true OM, and ME availability, partitioning factor (PF), volatile fatty acids (VFAs), and microbial biomass production were higher (P < 0.01) at 24 h as compared to t-half incubation, irrespective of type and level of HFAs supplemented. Acacia nilotica had an edge over Acacia catechu with respect to digestibility of nutrients and ME availability. VFAs production and efficiency of rumen fermentation was the highest from the Areca catechu-supplemented TMR. Irrespective of type of HFAs and incubation period, the digestibility of NDF and that of true OM were highest (P < 0.01) at the 1% level of supplementation, but depressed thereafter. Amongst HFAs-supplemented groups, VFA production and fermentation efficiency were highest at the 2% level. The results conclusively revealed that supplementing Areca catechu and Acacia nilotica at 2% of TMR (DM basis) inhibited the methane production, without affecting the fermentation pattern.
Changes In Serum Biochemical And Lipid Profile, And Fatty Acid Composition Of Breast Meat Of Broiler Chickens Fed Supplemental Grape Seed Extract, Özlem Karadağoğlu, Tarkan Şahi̇n, Mükremi̇n Ölmez, Akin Yakan, Bülent Özsoy
Changes In Serum Biochemical And Lipid Profile, And Fatty Acid Composition Of Breast Meat Of Broiler Chickens Fed Supplemental Grape Seed Extract, Özlem Karadağoğlu, Tarkan Şahi̇n, Mükremi̇n Ölmez, Akin Yakan, Bülent Özsoy
Turkish Journal of Veterinary & Animal Sciences
A study was conducted to evaluate the changes in serum biochemical and lipid profile, and fatty acid composition of breast meat of broiler chickens fed supplemental grape seed extract (GSE). A total of 240 1-day-old male broiler chickens were randomly allocated to 4 groups, each consisting of 4 replicate pens having 15 birds/replicate pen. One group served as control group fed basal diets and other groups received 100, 200, and 400 ppm GSE supplemented to the basal diets. Liver weight was greater in broilers fed 200 ppm GSE compared to the other groups (P = 0.004, L = 0.024, C …
The Effects Of Supplemental Niacin And Methionine On Serum Glucose, Betahydroxybutyric Acid, And Non-Esterified Fatty Acid Levels During Late Gestation And Early Postpartum Period In Damascus Dairy Goat, Mustafa Kemal Saribay, Ayşe Merve Köse, Bülent Özsoy, Umair Ahsan, Ece Koldaş Ürer, Serkan İrfan Köse, Gökhan Doğruer
The Effects Of Supplemental Niacin And Methionine On Serum Glucose, Betahydroxybutyric Acid, And Non-Esterified Fatty Acid Levels During Late Gestation And Early Postpartum Period In Damascus Dairy Goat, Mustafa Kemal Saribay, Ayşe Merve Köse, Bülent Özsoy, Umair Ahsan, Ece Koldaş Ürer, Serkan İrfan Köse, Gökhan Doğruer
Turkish Journal of Veterinary & Animal Sciences
The objective of this study was to assess the changes in serum glucose, beta-hydroxybutyric acid (ß-HBA), and nonesterified fatty acid (NEFA) levels in Damascus dairy goats fed niacin (Nia) and methionine (Met) during late gestation and early postpartum period. A total of 75 dairy goats at 105th day of gestation were divided into 3 groups as control (no supplementation), Nia (20 g/kg Nia), and Met (2.5 g/kg Met) groups. The dietary treatments continued until parturition. Dairy goats fed dietary Nia had greater serum glucose levels on day 125 of gestation compared to the other dietary treatments (P < 0.05). On day 135 of pregnancy, serum glucose levels were higher in Met group than control group (P < 0.05). Serum ß-HBA levels decreased on days 135 and 145 in dairy goats fed Nia than those in control group. Dietary Nia and Met lowered serum ß-HBA levels on day 10 postpartum compared to control group (P < 0.05). Serum NEFA levels decreased (P < 0.05) on days 135 and 145 in dairy goats fed Nia supplemented ration than those in control group. Serum NEFA levels d 10 postpartum were different among the groups (P < 0.05). In conclusion, dietary Nia and Met supplementation improved serum glucose levels on day 125 of gestation while decreasing ß-HBA and NEFA levels during late gestation and early postpartum period in Damascus dairy goats under the conditions of present study.
Effects Of Activated Charcoal And Zeolite On Serum Lipopolysaccharides And Someinflammatory Biomarkers Levels In Experimentally Induced Subacute Ruminal Acidosis Inlambs, Ali Abbas Nikvand, Mohammad Nouri, Mohammad Razi Jalali, Mohammad Reza Teimory Azadbakht
Effects Of Activated Charcoal And Zeolite On Serum Lipopolysaccharides And Someinflammatory Biomarkers Levels In Experimentally Induced Subacute Ruminal Acidosis Inlambs, Ali Abbas Nikvand, Mohammad Nouri, Mohammad Razi Jalali, Mohammad Reza Teimory Azadbakht
Turkish Journal of Veterinary & Animal Sciences
Bacterial lipopolysaccharides (LPS) play a key role in the pathogenesis of subacute ruminal acidosis (SARA). Limited attempts have been made to inhibit LPS absorption during SARA. Therefore, this study aimed to evaluate the impacts of oral usage of activated charcoal and zeolite on serum LPS and acute phase proteins (APPs) levels in lambs with SARA. Fifteen lambs were randomly assigned to 3 groups, each containing 5 lambs: control, activated charcoal, and zeolite. In all groups, SARA was induced for 7 days through increasing the crushed corn ration to 52.8% and reducing the rumen pH to the range of 5.7-5.6. In …
The Association Between The Route Of Nutrition And Serum Levels Of Adipokines In Critical Illness: A Pilot Study, Kürşat Gündoğan, Ender Doğan, Nurhayat Tuğra Özer, Gülşah Güneş Şahi̇n, Serap Şahi̇n, Murat Sungur, İsmai̇l Hakki Akbudak, Sabahatti̇n Muhtaroğlu, Muhammet Güven, Thomas R. Ziegler
The Association Between The Route Of Nutrition And Serum Levels Of Adipokines In Critical Illness: A Pilot Study, Kürşat Gündoğan, Ender Doğan, Nurhayat Tuğra Özer, Gülşah Güneş Şahi̇n, Serap Şahi̇n, Murat Sungur, İsmai̇l Hakki Akbudak, Sabahatti̇n Muhtaroğlu, Muhammet Güven, Thomas R. Ziegler
Turkish Journal of Medical Sciences
Background/aim: Adipokines play an important role in the regulation of metabolism. In critical illness, they alter serum levels and are suspected to worsen clinical outcomes. But the effect of the route of nutrition on adipokines is not known. The purpose of this study was to evaluate the association between the route of nutrition and adipokine levels in critically ill patients. Materials and methods: This prospective study was performed in an intensive care unit (ICU). Patients admitted to the ICU for least 72 h and receiving either enteral nutrition (EN) via tube feeding or parenteral nutrition (PN) were enrolled. Serum was …
Factors Associated With Severe Lung Disease In An Adult Population With Cystic Fibrosis: A Single-Center Experience, Berri̇n Er, Ebru Çelebi̇oğlu, Ebru Yalçin, Deni̇z Doğru, Özlem Erden Aki̇, Ömrüm Uzun, Murat Akova, Uğur Özçeli̇k, Nural Ki̇per, Sali̇h Emri̇
Factors Associated With Severe Lung Disease In An Adult Population With Cystic Fibrosis: A Single-Center Experience, Berri̇n Er, Ebru Çelebi̇oğlu, Ebru Yalçin, Deni̇z Doğru, Özlem Erden Aki̇, Ömrüm Uzun, Murat Akova, Uğur Özçeli̇k, Nural Ki̇per, Sali̇h Emri̇
Turkish Journal of Medical Sciences
Background/Aim: The patients with cystic fibrosis (CF) are living longer compared to the past, but respiratory failure is still the most common cause of mortality. The aim of this study is to investigate factors associated with severe lung disease in a cohort of adult patients with CF. Materials and methods: Demographic data, clinical and laboratory findings of the patients aged 18 years and more were collected and the patients were grouped according to forced expiratory volume in 1 s (FEV1) as severe group:
Risk Indices That Predict In-Hospital Mortality Of Elderly Patients, Di̇lek Dülger, Özgür Albuz
Risk Indices That Predict In-Hospital Mortality Of Elderly Patients, Di̇lek Dülger, Özgür Albuz
Turkish Journal of Medical Sciences
Background/aim: Mortality in the elderly population tends to be higher than in all other age groups; the risk factors that predict mortality among those in this age cohort are not fully understood. This large-scale clinical study aimed to identify effective risk factors that predict mortality in the elderly population with a particular focus on age and hospitalization status. Material and methods: We retrospectively analyzed outcomes from patients with clinical follow-up between July 2015 and January 2020 at 29 Mayıs State Hospital, Ankara, Turkey. Patient records with missing or ambiguous data were excluded. Age, sex, length of hospital stay, comorbidities, consultation …
Does Capsaicin Have Therapeutic Benefits In Human Colon Adenocarcinoma? Selection Of The Most Reliable Dose Via Agnor, Mustafa Ni̇sari̇, Recep Eröz
Does Capsaicin Have Therapeutic Benefits In Human Colon Adenocarcinoma? Selection Of The Most Reliable Dose Via Agnor, Mustafa Ni̇sari̇, Recep Eröz
Turkish Journal of Medical Sciences
Background/aim: To determine the effect of different doses of capsaicin on AgNOR protein synthesis in human colon adenocarcinoma derivate from colon cancer (Caco-2 cell). Materials and methods: In this experimental study, after the cultured of Caco-2 cell line, the cells are divided into 4 groups as control and different capsaicin exposed doses (25uµ, 50uµ, and 75uµ). Mean AgNOR number and total AgNOR area/nuclear area (TAA/NA) were calculated. Results: A significant differences were detected between control and capsaicin (50uµ) (P = 0.001), between control and capsaicin (75uµ) (P = 0.000), between capsaicin (25uµ) and capsaicin (50uµ) (P = 0.001) and between …
The Effect Of Rituximab On Encapsulated Peritoneal Sclerosis In An Experimental Rat Model, Süleyman Karaköse, Ayşe Zeynep Bal, Eylem Pinar Eser, Murat Duranay
The Effect Of Rituximab On Encapsulated Peritoneal Sclerosis In An Experimental Rat Model, Süleyman Karaköse, Ayşe Zeynep Bal, Eylem Pinar Eser, Murat Duranay
Turkish Journal of Medical Sciences
Background/aim: Peritoneal sclerosis may be observed in varied manifestations. However, the most serious form is the encapsulated peritoneal sclerosis. We researched the effect of rituximab on peritoneal fibrosis in an experimental rat model. Materials and methods: Twenty-four Wistar Albino rats were divided into 4 equal groups. During weeks 0-3; group I received isotonic saline (IS) solution, group II, group III, and group IV received chlorhexidine gluconate (CG) via intraperitoneal (i.p.) route. In the next 3 weeks nothing adminestred to both group I and group II but IS solution was adminestred to group III via i.p. route and 375 mg/m2/ week …
Nanotoxicity: A Challenge For Future Medicine, Ramazan Akçan, Hali̇t Canberk Aydogan, Mahmut Şeri̇f Yildirim, Burak Taşteki̇n, Necdet Sağlam
Nanotoxicity: A Challenge For Future Medicine, Ramazan Akçan, Hali̇t Canberk Aydogan, Mahmut Şeri̇f Yildirim, Burak Taşteki̇n, Necdet Sağlam
Turkish Journal of Medical Sciences
Background/aim: Due to nanomaterials' potential benefits for diagnosis and treatment, they are widely used in medical applications and personal care products. Interaction of nanomaterials, which are very small in size, with tissue, cell and microenvironment, can reveal harmful effects that cannot be created with chemically identical and larger counterparts in biological organisms. In this review, a challenge for future medicine, nanotoxicity of nanomaterials is discussed. Materials and methods: A detailed review of related literature was performed and evaluated as per medical applications of nanomaterials their toxicity. Results and conclusion: Most authors state "the only valid technology will be nanotechnology in …