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Articles 121 - 150 of 1022
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In Vitro Antimicrobial And Antibiofilm-Forming Activities Of Origanum Munzurense Plant Extract On Some Foodborne Gram-Negative Bacteria, Hali̇l Yalçin, Esra Zeybek, Oktay Özkan, Asim Kart
In Vitro Antimicrobial And Antibiofilm-Forming Activities Of Origanum Munzurense Plant Extract On Some Foodborne Gram-Negative Bacteria, Hali̇l Yalçin, Esra Zeybek, Oktay Özkan, Asim Kart
Turkish Journal of Veterinary & Animal Sciences
lants are an important source for the discovery of antimicrobial formulations due to the many biologically active components they contain. In this study, in vitro antimicrobial and antibiofilm forming activities of ethanolic extract of Origanum munzurense were investigated against some strains of foodborne pathogenic bacteria. To investigate the antimicrobial activity, the minimal inhibitory concentration values against the selected bacteria and antibiofilm-forming activity were tested with the liquid microdilution method and microplate method, respectively. MICs of Origanum munzurense extract against the bacteria tested are 32 mg/mL for Escherichia coli O157: H7 ATCC 35150, 32 mg/mL for Escherichia coli O157: H7 ATCC …
Novel Correlation Coefficients For Interval-Valued Fermatean Hesitant Fuzzy Sets With Pattern Recognition Application, İbrahi̇m Demi̇r
Novel Correlation Coefficients For Interval-Valued Fermatean Hesitant Fuzzy Sets With Pattern Recognition Application, İbrahi̇m Demi̇r
Turkish Journal of Mathematics
A combination of interval-valued Fermatean fuzzy sets with Fermatean hesitant fuzzy elements in the form of interval values is known as an interval-valued Fermatean hesitant fuzzy set. Since Fermatean hesitant fuzzy sets are effective instruments for representing more complex, ambiguous, and hazy information, interval-valued Fermatean hesitant fuzzy sets are expansions of these sets. This investigation will concentrate on four different types of correlation coefficients for Fermatean hesitant fuzzy sets and expand them to include correlation coefficients and weighted correlation coefficients for interval-valued Fermatean hesitant fuzzy sets. Finally, the numerical examples demonstrate the viability and usefulness of the suggested methodologies in …
On The Measure Of Noncompactness In $L_P(\Mathbb{R}^+)$ And Applications To A Product Of $N$-Integral Equations, Mohamed M. A. Metwali, Vishnu Narayan Mishra
On The Measure Of Noncompactness In $L_P(\Mathbb{R}^+)$ And Applications To A Product Of $N$-Integral Equations, Mohamed M. A. Metwali, Vishnu Narayan Mishra
Turkish Journal of Mathematics
In this article, we prove a new compactness criterion in the Lebesgue spaces $L_p({\mathbb{R}}^+), 1 \leq p < \infty$ and use such criteria to construct a measure of noncompactness in the mentioned spaces. The conjunction of that measure with the Hausdroff measure of noncompactness is proved on sets that are compact in finite measure. We apply such measure with a modified version of Darbo fixed point theorem in proving the existence of monotonic integrable solutions for a product of $n$-Hammerstein integral equations $n\geq 2$.
Significance Of The Immunofluorescence Staining Patterns And Titres Of The Antinuclear Antibody Test In Paediatric Rheumatology Setting, Özge Baba, Hakan Kisaoğlu, Mukaddes Kalyoncu
Significance Of The Immunofluorescence Staining Patterns And Titres Of The Antinuclear Antibody Test In Paediatric Rheumatology Setting, Özge Baba, Hakan Kisaoğlu, Mukaddes Kalyoncu
Turkish Journal of Medical Sciences
Background/aim: Antinuclear antibody (ANA) is among the most frequently ordered tests in paediatric rheumatology setting. Diseases like systemic lupus erythematosus and Sjögren syndrome is closely related with a positive ANA and classified as ANA associated diseases. Besides, ANA test is ordered in patients with juvenile idiopathic arthritis (JIA) to assess the risk for uveitis and a positive ANA could be detected in children with nonrheumaticrheumatic conditions. In this study, we aimed to investigate frequency of positive ANA in paediatric rheumatology setting and the association of immunofluorescence staining patterns and titres of ANA with rheumatic diseases. Materials and methods: Immunofluorescence staining …
The Impact Of Antiphospholipid Antibodies In Takayasu Arteritis, Esra Firat Şentürk, Abdulsamet Erden, Alper Sari, Berkan Armağan, Levent Kiliç, Umut Kalyoncu, Ömer Karadağ, Şazi̇ye Şule Apraş Bi̇lgen, Sedat Ki̇raz, Ali̇ İhsan Ertenli̇, Ali̇ Akdoğan
The Impact Of Antiphospholipid Antibodies In Takayasu Arteritis, Esra Firat Şentürk, Abdulsamet Erden, Alper Sari, Berkan Armağan, Levent Kiliç, Umut Kalyoncu, Ömer Karadağ, Şazi̇ye Şule Apraş Bi̇lgen, Sedat Ki̇raz, Ali̇ İhsan Ertenli̇, Ali̇ Akdoğan
Turkish Journal of Medical Sciences
Background/aim: The significance of antiphospholipid antibodies (aPL) is controversial in Takayasu arteritis (TA). This study was conducted to explore the frequency of aPL and their association with disease-related complications in TA. Materials and methods: This cross-sectional study was conducted to investigate the presence of anti-cardiolipin (aCL), anti-beta 2 glycoprotein- 1(aß2G1) antibodies, and lupus anticoagulant (LA) in TA patients. TA patients admitted to the Department of Rheumatology of Hacettepe University Faculty of Medicine between December 2015 and September 2016 who fulfilled the American College of Rheumatology (ACR) classification criteria for TA were consecutively enrolled in the study. Patients were grouped according …
Tularemia Seroprevalence In Humans In The Region Of The Hittite-Arzawa War (Inner Aegean Region), Where The First Biological Weapon Was Used 3300 Years Ago, İsmai̇l Davarci, Canan Eryildiz, Duygu Perçi̇n Renders, Ufuk Berberoğlu, Şaban Gürcan
Tularemia Seroprevalence In Humans In The Region Of The Hittite-Arzawa War (Inner Aegean Region), Where The First Biological Weapon Was Used 3300 Years Ago, İsmai̇l Davarci, Canan Eryildiz, Duygu Perçi̇n Renders, Ufuk Berberoğlu, Şaban Gürcan
Turkish Journal of Medical Sciences
Background/aim: According to Egyptian records, tularemia emerged in the Canaan region, where it was first identified and spread to Anatolia over the Euphrates. It was used as an active biological weapon for the first time in the Hittite-Arzawa War in 1320-1318 BC. This study aimed to investigate the seroprevalence of tularemia in the Inner Aegean Region, which is thought to be the region where this war was fought 3300 years ago. Materials and methods: Tularemia seropositivity in humans was investigated in 27 villages/neighborhoods in 3 districts in each of Manisa, Kütahya, and Uşak provinces. Before the study, the participants were …
Covid-19 Modeling Based On Real Geographic And Population Data, Emi̇r Baysazan, Ahmet Ni̇hat Berker, Hasan Mandal, Hakan Kaygusuz
Covid-19 Modeling Based On Real Geographic And Population Data, Emi̇r Baysazan, Ahmet Ni̇hat Berker, Hasan Mandal, Hakan Kaygusuz
Turkish Journal of Medical Sciences
Background/aim: Intercity travel is one of the most important parameters for combating a pandemic. The ongoing COVID-19 pandemic has resulted in different computational studies involving intercity connections. In this study, the effects of intercity connections during an epidemic such as COVID-19 are evaluated using a new network model. Materials and methods: This model considers the actual geographic neighborhood and population density data. This new model is applied to actual Turkish data by means of provincial connections and populations. A Monte Carlo algorithm with a hybrid lattice model is applied to a lattice with 8802 data points. Results: Around Monte Carlo …
Risk Factors For Icu Mortality In Patients With Hematological Malignancies: A Singlecenter, Retrospective Cohort Study From Turkey, Şahender Gülbi̇n Aygencel Bikmaz, Onur Gökçe, Meryem Merve Haşi̇moğlu, Nazlihan Boyaci, Melda Türkoğlu, Zeynep Arzu Yegi̇n, Zübeyde Nur Özkurt, Abdullah Münci̇ Yağci
Risk Factors For Icu Mortality In Patients With Hematological Malignancies: A Singlecenter, Retrospective Cohort Study From Turkey, Şahender Gülbi̇n Aygencel Bikmaz, Onur Gökçe, Meryem Merve Haşi̇moğlu, Nazlihan Boyaci, Melda Türkoğlu, Zeynep Arzu Yegi̇n, Zübeyde Nur Özkurt, Abdullah Münci̇ Yağci
Turkish Journal of Medical Sciences
Background/aim: Patients with hematological malignancies (HM) often require admission to the intensive care unit (ICU) due to organ failure, disease progression or treatment-related complications, and they generally have a poor prognosis. Therefore, understanding the factors affecting ICU mortality in HM patients is important. In this study, we aimed to identify the risk factors for ICU mortality in our critically ill HM patients. Materials and methods: We retrospectively reviewed the medical records of HM patients who were hospitalized in our medical ICU between January 1, 2010 and December 31, 2018. We recorded some parameters of these patients and compared these parameters …
Evaluation Of Prognostic Scoring Systems In Patients Hospitalized From The Emergency Department In A Low-Income Region: Northern Syria After Internal Turmoil As A Different Universe, Burak Çeli̇k, Bahadir Karaca
Evaluation Of Prognostic Scoring Systems In Patients Hospitalized From The Emergency Department In A Low-Income Region: Northern Syria After Internal Turmoil As A Different Universe, Burak Çeli̇k, Bahadir Karaca
Turkish Journal of Medical Sciences
Background/aim: In low-income or underdeveloped countries with conflict and internal unrest, healthcare facilities and staff are limited. For these reasons, it is necessary to use the most straightforward scoring systems to ensure that health facilities and staff are used effectively and to expedite processes through early and effective interventions for patients. In this study, we evaluate and compare the scoring systems used to predict patient prognosis for Emergency Department (ED) patients in northern Syria, which is an area marred by conflict and internal unrest. Materials and methods: In this study, patients hospitalized in the Afrin, Azez Vatan, Jarablus, Tel Abyad, …
New Insights On Epidemiology Of Infectious Bronchitis Virus In Iran By Comparing Two Genotyping Methods, Arash Ghalyanchilangeroudi, Hossein Hosseini, Zahra Ziafati Kafi, Naser Sadri, Ali Hojabr Rajeoni, Hamideh Najafi
New Insights On Epidemiology Of Infectious Bronchitis Virus In Iran By Comparing Two Genotyping Methods, Arash Ghalyanchilangeroudi, Hossein Hosseini, Zahra Ziafati Kafi, Naser Sadri, Ali Hojabr Rajeoni, Hamideh Najafi
Turkish Journal of Veterinary & Animal Sciences
Different genotypes of infectious bronchitis virus (IBV) in poultry are circulating worldwide. The most efficient classification system for IBV genotypes is based on the complete sequencing of S1 gene, and the target organ can be trachea, kidney, oviduct, lung, esophagus, proventriculus, intestine, liver, spleen, bursa, cecal tonsils, cloaca, and testis. In Iran, IBV genotyping is usually performed by partial sequencing of S1 gene, and the trachea is often selected for sampling. This study applies a different genotyping method, and compares the results with the routine method of genotyping. Samples were collected from the trachea and kidneys of 50 broiler flocks …
A Type-2 Fuzzy Rule-Based Model For Diagnosis Of Covid-19, İhsan Şahi̇n, Erhan Akdoğan, Mehmet Emi̇n Aktan
A Type-2 Fuzzy Rule-Based Model For Diagnosis Of Covid-19, İhsan Şahi̇n, Erhan Akdoğan, Mehmet Emi̇n Aktan
Turkish Journal of Electrical Engineering and Computer Sciences
In this study, a type-2 fuzzy logic-based decision support system comprising clinical examination and blood test results that health professionals can use in addition to existing methods in the diagnosis of COVID-19 has been developed. The developed system consists of three fuzzy units. The first fuzzy unit produces COVID-19 positivity as a percentage according to the respiratory rate, loss of smell, and body temperature values, and the second fuzzy unit according to the C-reactive protein, lymphocyte, and D-dimer values obtained as a result of the blood tests. In the third fuzzy unit, the COVID-19 positivity risks according to the clinical …
Serum Trace Element Levels In Dogs With Canine Visceral Leishmaniasis, Aycan Nuri̇ye Gazyağci, Bengü Bi̇lgi̇ç, Berna Baysal Bakay, Duygu Tarhan, Alev Meltem Ercan, Songül Erdoğan, Hasan Erdoğan, Mehmet Erman Or, Kerem Ural
Serum Trace Element Levels In Dogs With Canine Visceral Leishmaniasis, Aycan Nuri̇ye Gazyağci, Bengü Bi̇lgi̇ç, Berna Baysal Bakay, Duygu Tarhan, Alev Meltem Ercan, Songül Erdoğan, Hasan Erdoğan, Mehmet Erman Or, Kerem Ural
Turkish Journal of Veterinary & Animal Sciences
Canine visceral leishmaniasis has been denoted as neglected despite being a very well-known disease. Trace element alteration has been recognized in humans with visceral and cutaneous leishmaniasis, together with canine visceral leishmaniasis. The trace elements occupy a vital position in the immunological system, and host immune responses mitigate defense against leishmaniasis. We aimed to select trace elements in a total of 45 dogs of several breeds; those at the age of 11 months to 6 and from both sexes (26 male and 19 female) were enrolled in the study. The dogs included in the study were divided into leishmaniasis-infected and …
Does Apocynin Increase Liver Regeneration In The Partial Hepatectomy Model?, Yilmaz Bi̇lgi̇ç, Burhan Hakan Kanat, Onural Özhan, Azi̇be Yildiz, Zeynep Aksungur, Mehmet Erman Erdemli̇, Ni̇gar Vardi, Yusuf Türköz, Ahmet Sami̇ Akbulut, Adem Köse, Hakan Parlakpinar
Does Apocynin Increase Liver Regeneration In The Partial Hepatectomy Model?, Yilmaz Bi̇lgi̇ç, Burhan Hakan Kanat, Onural Özhan, Azi̇be Yildiz, Zeynep Aksungur, Mehmet Erman Erdemli̇, Ni̇gar Vardi, Yusuf Türköz, Ahmet Sami̇ Akbulut, Adem Köse, Hakan Parlakpinar
Turkish Journal of Medical Sciences
Background/aim: Hepayocyte loss may develop secondary to liver surgery and at this point liver regeneration plays a significant act in terms of liver reserve. The purpose of this research was to investigate the efficacy of apocynin on liver regeneration and preservation after partial hepatectomy in rats. Materials and methods: A total of 32 rats, have been divided into 4 groups (n: 8) for hepatectomy model. Inflammatory and antiinflammatory parameters were measured from blood and liver tissue samples. In addition, the effects of apocynin were examined immunohistochemically and histopathologically from liver tissue. Results: In liver tissue samples, a significant difference has …
Multidrug Resistance In Pathogens Of Community-Acquired Urinary Tract Infections In Turkey: A Multicentre Prospective Observational Study, İrfan Şencan, Oğuz Karabay, Fatma Aybala Altay, Serap Süzük Yildiz, Hüsni̇ye Şi̇mşek, Meli̇h Gaffar Gözükara, Semanur Kuzi̇, Gülden Eser Karlidağ, Şafak Kaya, Gülnur Kul, Emi̇ne Türkoğlu, Büşra Ergüt Sezer, Nesi̇be Korkmaz, Si̇bel Yildiz Kaya, Merve Sefa Sayar
Multidrug Resistance In Pathogens Of Community-Acquired Urinary Tract Infections In Turkey: A Multicentre Prospective Observational Study, İrfan Şencan, Oğuz Karabay, Fatma Aybala Altay, Serap Süzük Yildiz, Hüsni̇ye Şi̇mşek, Meli̇h Gaffar Gözükara, Semanur Kuzi̇, Gülden Eser Karlidağ, Şafak Kaya, Gülnur Kul, Emi̇ne Türkoğlu, Büşra Ergüt Sezer, Nesi̇be Korkmaz, Si̇bel Yildiz Kaya, Merve Sefa Sayar
Turkish Journal of Medical Sciences
Background/aim: To have country-wide information about multidrug resistance (MDR) in isolates from community-acquired urinary tract infections (CAUTI) of Turkey, in terms of resistance rates and useful options. Materials and methods: We used a geocode standard, nomenclature of territorial units for statistics (NUTS), and a total of 1588 community-acquired isolates of 20 centres from 12 different NUTS regions between March 2019 and March 2020 were analysed. Results: Of the 1588 culture growths, 1269 (79. 9%) were Escherichia coli and 152 (9.6%) were Klebsiella spp. Male sex, advanced age, and having two or more risk factors showed a statistically significant relation with …
Cryogenic X-Ray Crystallographic Studies Of Biomacromolecules At Turkish Light Source "Turkish Delight", Necati̇ Atalay, Enver Kami̇l Akcan, Mehmet Gül, Esra Ayan, Ebru Destan, Fatma Betül Ertem Kuzucu, Nuretti̇n Tokay, Bariş Çakilkaya, Zeli̇ş Nergi̇z, Gözde Karakadioğlu Usta, Abdullah Kepceoğlu, İlki̇n Yapici, Bi̇lge Tosun, Ni̇lüfer Baldir, Günseli̇ Yildirim, J Austin Johnson, Ömür Güven, Alaleh Shafiei, Nazli Eylül Arslan, Merve Yilmaz, Cahi̇ne Kulakman, Seyi̇de Seda Paydos, Seynep Sena Çi̇nal, Kardelen Şabanoğlu, Ayşegül Pazarçevi̇ren, Ayşenur Yilmaz, Başak Canbay, Bengi̇su Aşçi, Esra Kartal, Serra Tavli, Mehmet Çaliseki̇, Günce Göç, Ari̇f Mermer, Gamze Yeşi̇lay, Sevde Altuntaş, Hiroshi Tateishi, Masami Otsuka, Mikako Fujita, Şaban Teki̇n, Hali̇li̇brahi̇m Çi̇ftçi̇, Serdar Durdaği, Gi̇zem Di̇nler Doğanay, Ezgi̇ Karaca, Burcu Kaplan Türköz, Burak Veli̇ Kabasakal, Ahmet Kati, Hasan Demi̇rci̇
Cryogenic X-Ray Crystallographic Studies Of Biomacromolecules At Turkish Light Source "Turkish Delight", Necati̇ Atalay, Enver Kami̇l Akcan, Mehmet Gül, Esra Ayan, Ebru Destan, Fatma Betül Ertem Kuzucu, Nuretti̇n Tokay, Bariş Çakilkaya, Zeli̇ş Nergi̇z, Gözde Karakadioğlu Usta, Abdullah Kepceoğlu, İlki̇n Yapici, Bi̇lge Tosun, Ni̇lüfer Baldir, Günseli̇ Yildirim, J Austin Johnson, Ömür Güven, Alaleh Shafiei, Nazli Eylül Arslan, Merve Yilmaz, Cahi̇ne Kulakman, Seyi̇de Seda Paydos, Seynep Sena Çi̇nal, Kardelen Şabanoğlu, Ayşegül Pazarçevi̇ren, Ayşenur Yilmaz, Başak Canbay, Bengi̇su Aşçi, Esra Kartal, Serra Tavli, Mehmet Çaliseki̇, Günce Göç, Ari̇f Mermer, Gamze Yeşi̇lay, Sevde Altuntaş, Hiroshi Tateishi, Masami Otsuka, Mikako Fujita, Şaban Teki̇n, Hali̇li̇brahi̇m Çi̇ftçi̇, Serdar Durdaği, Gi̇zem Di̇nler Doğanay, Ezgi̇ Karaca, Burcu Kaplan Türköz, Burak Veli̇ Kabasakal, Ahmet Kati, Hasan Demi̇rci̇
Turkish Journal of Biology
X-ray crystallography is a robust and powerful structural biology technique that provides high-resolution atomic structures of biomacromolecules. Scientists use this technique to unravel mechanistic and structural details of biological macromolecules (e.g., proteins, nucleic acids, protein complexes, protein-nucleic acid complexes, or large biological compartments). Since its inception, single-crystal cryocrystallography has never been performed in Türkiye due to the lack of a single-crystal X-ray diffractometer. The X-ray diffraction facility recently established at the University of Health Sciences, İstanbul, Türkiye will enable Turkish and international researchers to easily perform high-resolution structural analysis of biomacromolecules from single crystals. Here, we describe the technical and …
Genotoxic Effects Of Oxyclozanide On Hemocytes Of Galleria Mellonella (Lepidoptera: Pyralidae) Larvae, Ci̇hat Çeli̇k, David Stanley, Ender Büyükgüzel
Genotoxic Effects Of Oxyclozanide On Hemocytes Of Galleria Mellonella (Lepidoptera: Pyralidae) Larvae, Ci̇hat Çeli̇k, David Stanley, Ender Büyükgüzel
Turkish Journal of Zoology
Oxyclozanide is a salicylanilide derivative anthelmintic drug with a well-known effect on parasites that cause infections in humans and animals. In this study, the effect of oxyclozanide on DNA damage in hemocytes of Galleria mellonella (L.) (Lepidoptera: Pyralidae) larvae, which has been used as a model organism in many fields, was investigated. Hemolymph was collected from the last instar larvae (7th instar) reared on artificial diets containing oxyclozanide at different concentrations (0.003%, 0.03%, 0.3%, and 1.5%) under laboratory conditions and then hemocytes suspension was prepared. Genotoxic damage in hemocytes was determined by the comet assay which enables microscopically detecting DNA …
Is It Tuberculosis Mastitis Or Granulomatous Mastitis? A Thirteen-Year Experience At A University Hospital, Handan İnönü Köseoğlu, Mehmet Fati̇h Daşiran, Reşi̇t Doğan Köseoğlu, Zeki̇ye Ruken Yüksekkaya Çeli̇kyay, Mehmet Berati̇ Kaleli̇oğlu
Is It Tuberculosis Mastitis Or Granulomatous Mastitis? A Thirteen-Year Experience At A University Hospital, Handan İnönü Köseoğlu, Mehmet Fati̇h Daşiran, Reşi̇t Doğan Köseoğlu, Zeki̇ye Ruken Yüksekkaya Çeli̇kyay, Mehmet Berati̇ Kaleli̇oğlu
Turkish Journal of Medical Sciences
Background/aim: Granulomatous mastitis (GM) is a rare inflammatory disease of the breast. Tuberculosis mastitis (TM), one of the causes of GM, is a rare form of extrapulmonary tuberculosis. The clinical, radiological, and histopathological findings of TM and GM are similar, and sometimes it is difficult to make a distinction between these disease states. In this study, we aimed to evaluate the clinical and radiological features, diagnostic techniques, treatment modalities and treatment outcomes of the patients with GM and TM. Materials and methods: The data of the patients with confirmed GM by histopathologic examination of biopsy specimens between 2007 and 2020 …
Molecular Phylogenetics Of Aedes Aegypti (L., 1762) (Diptera: Culicidae) In Eastern Black Sea Area Of Turkey And Possible Relations With The Caucasian Invasion, Murat Öztürk, Muhammet Mustafa Akiner
Molecular Phylogenetics Of Aedes Aegypti (L., 1762) (Diptera: Culicidae) In Eastern Black Sea Area Of Turkey And Possible Relations With The Caucasian Invasion, Murat Öztürk, Muhammet Mustafa Akiner
Turkish Journal of Zoology
Aedes aegypti (L., 1762) (Diptera: Culicidae) is an important pest for human health. It vectors many diseases, including yellow fever (YF), dengue (DENV), and chikungunya (CHIKV). This species has invaded numerous countries including Balkan and Caucasian countries few past decades. The established populations of species were found in Turkey in 2015. We investigated the genetic variation, molecular phylogenetics, and differences between samples from Turkey and Georgia using four mitochondrial and one genomic DNA markers. The possible origin of the species was determined separately for each gene region using maximum likelihood trees. The ML analysis showed a close relation with the …
Evaluation Of Treatment Regimens And Long-Term Clinical Outcomes In Patients With Isoniazid-Resistant Pulmonary Tuberculosis: A 5-Year Follow-Up, Ayşe Feyza Aslan, Medi̇ha Gönenç Ortaköylü, Belma Akbaba Bağci, Sezer Toprak
Evaluation Of Treatment Regimens And Long-Term Clinical Outcomes In Patients With Isoniazid-Resistant Pulmonary Tuberculosis: A 5-Year Follow-Up, Ayşe Feyza Aslan, Medi̇ha Gönenç Ortaköylü, Belma Akbaba Bağci, Sezer Toprak
Turkish Journal of Medical Sciences
Background/aim: Considering its early bactericidal activity, isoniazid (H) is an important first-line agent in tuberculosis (TB) treatment. The aim of this study was to evaluate the treatment regimens and results of H-resistant pulmonary TB patients. Materials and methods: We retrospectively evaluated treatment regimens and results of 188 H-resistant pulmonary TB patients who were treated in our center between January 2015 and December 2017. Treatment regimens applied were noted and treatment outcomes were recorded. The long-term results were evaluated. Results: Totally 174 (92.6%) of 188 patients with H-resistant pulmonary TB achieved treatment success. Ninety-seven patients (51.6%) were cured and 77 patients …
Occurrence Of Staphylococcus Aureus In Milk And Antibacterial Properties Of Some Herbal Extracts On Milk And Hospital-Acquired Strains, Reza Ebrahimi Hariry, Gülçi̇n Akca, Ayhan Fi̇lazi̇
Occurrence Of Staphylococcus Aureus In Milk And Antibacterial Properties Of Some Herbal Extracts On Milk And Hospital-Acquired Strains, Reza Ebrahimi Hariry, Gülçi̇n Akca, Ayhan Fi̇lazi̇
Turkish Journal of Veterinary & Animal Sciences
Staphylococcus aureus is a remarkable infectious agent, and with the development of antibiotic resistance by S. aureus, finding new, effective, and safe alternative therapeutic options in animals and humans is crucially demanded. In this study, the occurrence of S. aureus was explored by collecting nonmastitis bovine milk samples first, and then the effects of herbal extracts on methicillinresistant S. aureus (MRSA) strains isolated from cow's milk and humans in the hospitals were investigated. The occurrences of S. aureus in bovine raw milk samples were 13.4%. All raw milk S. aureus isolates were fully susceptible to cefoxitin, ceftiofur, penicillin G, …
Phenotypic And Genotypic Characterization Of Antimicrobial Resistance In Commonly Isolated Salmonella Serovars From Chickens, Seyyi̇de Sariçam İnce, Mehmet Akan
Phenotypic And Genotypic Characterization Of Antimicrobial Resistance In Commonly Isolated Salmonella Serovars From Chickens, Seyyi̇de Sariçam İnce, Mehmet Akan
Turkish Journal of Veterinary & Animal Sciences
Salmonellosis caused by Salmonella agents is the second most common zoonotic infection in humans. In recent years, Salmonella's increasing antimicrobial resistance (AMR) has been a concern. The major transmission route of Salmonella is consumption of contaminated poultry products. Therefore, monitoring of antimicrobial resistance in chicken-originated Salmonella is critically important. This study investigated AMR in four commonly isolated Salmonella serovars from chickens, namely Salmonella Enteritidis (S. Enteritidis), Salmonella Infantis (S. Infantis), Salmonella Kentucky (S. Kentucky), and Salmonella Typhimurium (S. Typhimurium). A total of 133 isolates were examined by phenotypic and genotypic AMR characterization. Resistance to 14 different antimicrobials and eight …
Examination Of Canine Herpesvirus-1 In Dogs By Serological, Molecular, And Pathological Methods, Serkan Yildirim, Fatma Gülten Bayraktar, Hakan Aydin, Yavuz Seli̇m Sağlam, Gi̇zem Eser, Muhammet Bahaeddi̇n Dörtbudak
Examination Of Canine Herpesvirus-1 In Dogs By Serological, Molecular, And Pathological Methods, Serkan Yildirim, Fatma Gülten Bayraktar, Hakan Aydin, Yavuz Seli̇m Sağlam, Gi̇zem Eser, Muhammet Bahaeddi̇n Dörtbudak
Turkish Journal of Veterinary & Animal Sciences
In this study, it was aimed to examine Canine Herpesvirus-1 (CHV-1) with different diagnostic methods and investigate the pathological changes in positive samples. For this purpose, 100 dog uteruses of different ages and breeds, were removed by ovariohysterectomy and their blood samples were used as the study material. Enzyme-linked immunosorbent assay (ELISA) and Indirect Fluorescent Antibody Test (IFAT) for serological diagnosis, polymerase chain reaction (PCR) method for molecular diagnosis, immunohistochemistry (IHC) and immunofluorescence (IF) staining for immunopathological diagnosis were performed on the samples. Additionally, hematoxylin and eosin (HE) staining was performed to examine the histopathological changes in the CHV- 1-positive …
Removal Of Amoxicillin Via Chromatographic Monolithic Columns: Comparison Between Batch And Continuous Fixed Bed, Mustafa Deni̇z Ağlamaz, Koray Şarkaya, Deni̇z Türkmen, Mustafa Uçar, Adi̇l Deni̇zli̇
Removal Of Amoxicillin Via Chromatographic Monolithic Columns: Comparison Between Batch And Continuous Fixed Bed, Mustafa Deni̇z Ağlamaz, Koray Şarkaya, Deni̇z Türkmen, Mustafa Uçar, Adi̇l Deni̇zli̇
Turkish Journal of Chemistry
This study presented a hydrophobic interaction-based poly(HEMA-MATrp) monolithic chromatographic column (MCC) to remove amoxicillin from aqueous solutions. In addition to their porous structure, monolithic-filled columns offer superior properties without loss of performance, which is one of the points that make them unique. The specific surface area of the monolithic column synthesized by the bulk polymerization of 2-hydroxyethyl methacrylate and N-Methacryloyl-L-tryptophan. Also, poly(HEMAMATrp) MCC has been characterized via FTIR, SEM, and elemental analysis. According to BET analysis, the specific surface area of the poly(HEMA-MATrp) monolithic chromatographic column (MCC) is 14.2 mg/g. The adsorption and desorption of amoxicillin in an aqueous solution …
Sars-Cov-2 Main Protease Targeting Potent Fluorescent Inhibitors: Repurposing Thioxanthones, Gönül Saadet Batibay, Eyüp Meti̇n
Sars-Cov-2 Main Protease Targeting Potent Fluorescent Inhibitors: Repurposing Thioxanthones, Gönül Saadet Batibay, Eyüp Meti̇n
Turkish Journal of Chemistry
The coronavirus disease, COVID-19, is the major focus of the whole world due to insufficient treatment options. It has spread all around the world and is responsible for the death of numerous human beings. The future consequences for the disease survivors are still unknown. Hence, all contributions to understand the disease and effectively inhibit the effects of the disease have great importance. In this study, different thioxanthone based molecules, which are known to be fluorescent compounds, were selectively chosen to study if they can inhibit the main protease of SARS-CoV-2 using various computational tools. All candidate ligands were optimized, molecular …
Blockchain And Federated Learning-Based Security Solutions For Telesurgery System: A Comprehensive Review, Sachi Chaudjary, Riya Kakkar, Rajesh Gupta, Sudeep Tanwar, Smita Agrawal, Ravi Sharma
Blockchain And Federated Learning-Based Security Solutions For Telesurgery System: A Comprehensive Review, Sachi Chaudjary, Riya Kakkar, Rajesh Gupta, Sudeep Tanwar, Smita Agrawal, Ravi Sharma
Turkish Journal of Electrical Engineering and Computer Sciences
The advent of telemedicine with its remote surgical procedures has effectively transformed the working of healthcare professionals. The evolution of telemedicine facilitates the remote monitoring of patients that lead to the advent of telesurgery systems, i.e. one of the most critical applications in telemedicine systems. Apart from gaining popularity, the telesurgery system may encounter security and trust issues of patients? data while communicating with the surgeon for their remote treatment. Motivated by this, we have presented a comprehensive survey on secure telesurgery systems comprising healthcare, surgical robots, traditional telesurgery systems, and the role of artificial intelligence to deal with the …
Mocmin: Convex Inferring Of Modular Low-Rank Contact Networks Over Covid Diffusion Data, Emre Sefer
Mocmin: Convex Inferring Of Modular Low-Rank Contact Networks Over Covid Diffusion Data, Emre Sefer
Turkish Journal of Electrical Engineering and Computer Sciences
SEIR (which consists of susceptible, exposed, infected, and recovered states) is a common diffusion model which could model different disease propagation dynamics across various domains such as influenza and COVID diffusion. As a motivation, across these domains, observing the node states is relatively easier than observing the network edges over which the diffusion is taking place, or it may not even be possible to observe the underlying network. This paper focuses on the problem of predicting modular low-rank human contact network edges only if a SEIR diffusion dynamics spreading among the human on their contact network can be observed. Such …
Developing A Fake News Identification Model With Advanced Deep Languagetransformers For Turkish Covid-19 Misinformation Data, Mehmet Bozuyla, Akin Özçi̇ft
Developing A Fake News Identification Model With Advanced Deep Languagetransformers For Turkish Covid-19 Misinformation Data, Mehmet Bozuyla, Akin Özçi̇ft
Turkish Journal of Electrical Engineering and Computer Sciences
The massive use of social media causes rapid information dissemination that amplifies harmful messages such as fake news. Fake-news is misleading information presented as factual news that is generally used to manipulate public opinion. In particular, fake news related to COVID-19 is defined as 'infodemic' by World Health Organization. An infodemic is a misleading information that causes confusion which may harm health. There is a high volume of misinformation about COVID-19 that causes panic and high stress. Therefore, the importance of development of COVID-19 related fake news identification model is clear and it is particularly important for Turkish language from …
Distribution And Molecular Differentiation Of Culex Pipiens Complex Species In Themiddle And Eastern Black Sea Regions Of Turkey, Muhammet Mustafa Akiner, Murat Öztürk, Fati̇h Şaban Beri̇ş, Çağaşan Karacaoğlu, Fati̇h Mehmet Şi̇mşek, Aytül Uzun Akgeyi̇k
Distribution And Molecular Differentiation Of Culex Pipiens Complex Species In Themiddle And Eastern Black Sea Regions Of Turkey, Muhammet Mustafa Akiner, Murat Öztürk, Fati̇h Şaban Beri̇ş, Çağaşan Karacaoğlu, Fati̇h Mehmet Şi̇mşek, Aytül Uzun Akgeyi̇k
Turkish Journal of Zoology
Culex pipiens species complex is commonly found in tropical and subtropical areas. Identification of species complexes and their spatial distribution patterns are fundamental steps needed to improve our understanding of arboviral disease circulation and their control. The specimens were differentiated using the Ace-2 gene, and the ecological forms of Culex pipiens were identified by analysis of the CQ11 microsatellite locus. Results showed that all sample points comprised of Culex pipiens s.s., and seven points contained Culex torrentium. Further, we determined that 22 haplotypes from five haplogroups were identified within the Ace-2 marker, and three haplotypes were contained within the CQ11 …
Evaluation Of The Feeding Patterns Of Important Mosquito Vector Species Using Molecular Techniques, Fatma Bursali, Fati̇h Mehmet Şi̇mşek
Evaluation Of The Feeding Patterns Of Important Mosquito Vector Species Using Molecular Techniques, Fatma Bursali, Fati̇h Mehmet Şi̇mşek
Turkish Journal of Zoology
This study investigated the feeding patterns of populations of Anopheles sacharovi, Culex tritaeniorhynchus, and Culex pipiens in the Mediterranean and Aegean regions of Turkey. Blood-fed females resting inside barns, houses, and chicken coops in the rural areas were collected between May 2017 and September 2019, and the genomic DNA from each female was isolated to determine the blood source after amplification of the mitochondrial cytochrome b gene region. Cytb results showed that out of 445 blood-fed An. sacharovi females 2 blood-fed from dogs, 9 from birds, and 434 from cows. The results also showed that all 216 blood-fed females Cx. …
Recombinant Ahpc Antigen From Mycobacterium Bovis Boosts Bcg-Primed Immunity In Mice, Özgün Firat Düzenli̇, Sezer Okay, İnci̇ Kazkayasi Bölük, Ayşe Fi̇li̇z Öner
Recombinant Ahpc Antigen From Mycobacterium Bovis Boosts Bcg-Primed Immunity In Mice, Özgün Firat Düzenli̇, Sezer Okay, İnci̇ Kazkayasi Bölük, Ayşe Fi̇li̇z Öner
Turkish Journal of Biology
Tuberculosis (TB) is still one of the most common infectious diseases around the world despite the widespread use of BCG (bacille Calmette-Guerin) strain of Mycobacterium bovis as a vaccine. This vaccine does not always protect people from TB, and, thus, new effective vaccines or vaccination strategies are being investigated. In this study, alkyl hydroperoxide reductase (AhpC) from M. bovis was evaluated as a new candidate vaccine antigen against TB in BALB/c mice model. The ahpC gene was amplified from M.bovis genome, cloned, and expressed in Escherichia coli. Vaccine antigen AhpC was formulated with Montanide ISA 61 VG, an oil-based emulsion …