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Full-Text Articles in Entire DC Network
Histological Changes Induced By Sialoadenectomy And Flutamide On The Epididymal Tissue And Epididymal Abnormalities, M.Aydin Ketani̇, Ahmet Ersay, Yusuf Nergi̇z, Mustafa Deni̇z, Şennur Ketani̇
Histological Changes Induced By Sialoadenectomy And Flutamide On The Epididymal Tissue And Epididymal Abnormalities, M.Aydin Ketani̇, Ahmet Ersay, Yusuf Nergi̇z, Mustafa Deni̇z, Şennur Ketani̇
Turkish Journal of Biology
In this study the purpose was to determine the effect of sialoadenectomy (Maternal Epidermal Growth Factor deficiency) on epididymal development and to compare it with that of antiandrogen (Flutamide) application.Forty 12-week-old, sexually mature and pregnant Sprague-Dawley rats were chosen as the animal model. They were divided into four groups; Group I : Control group, Group II : Sialoadenectomized (mated on 28^{th} day), Group III: Flutamide applied (between gestational day 11 and 21), Group IV: Sialoadenectomy + Flutamide applied. After birth, all male rats were observed morphologically on the 60th day and sacrificed on the 60^{th} day postpartum under general anaesthesia. …
The Effect Of Sulphur Dioxide On Macrophage Phagocytic Activity In Diabetic Rats, Veci̇he Ni̇met İzgüt Uysal, Vural Küçükatay, Aysel Ağar, Pi̇raye Yargiçoğlu
The Effect Of Sulphur Dioxide On Macrophage Phagocytic Activity In Diabetic Rats, Veci̇he Ni̇met İzgüt Uysal, Vural Küçükatay, Aysel Ağar, Pi̇raye Yargiçoğlu
Turkish Journal of Biology
Sulphur dioxide as a criterion of air pollution supresses macrophage functions. Some immunological changes in diabetes mellitus have been detected. In the present study, we examined the effect of sulphur dioxide on macrophage phagocytic activity in diabetic rats. The animals were separated into four groups as: 1) Control, 2) Sulphur dioxide, 3) Diabetes mellitus, 4) Diabetes mellitus+sulphur dioxide. The first and the third groups of animals were respirated with filtered atmosphere air in a special chamber one hour daily for eight weeks, while the other groups were exposed to 10 ppm sulphur dioxide in the same conditions and periods. The …
Effects Of Growth Hormone On Hepatic Regeneration, Mahmut Başoğlu, Ahmet A. Balik, İbrahi̇m Kavak, Cemal Gündoğdu, Zekai̇ Erman, İlhan Yildirgan, Durkaya Ören
Effects Of Growth Hormone On Hepatic Regeneration, Mahmut Başoğlu, Ahmet A. Balik, İbrahi̇m Kavak, Cemal Gündoğdu, Zekai̇ Erman, İlhan Yildirgan, Durkaya Ören
Turkish Journal of Medical Sciences
The aim of this experimental study was to determine the effects of growth hormone on hepatic regeneration after partial hepatectomy. Thirty pathogen free Sprague-Dawley rats were divided into three groups, each containing 10 rats. The animals were subjected to a sham operation in Group 1, and to left hepatic lobectomy in Groups 2 and 3. The animals in Groups 1 and 2 received saline solution (0.2 mg/kg/day), while growth hormone (Lilly Humotrope, Lilly France Usine de Fegersheim, France) (0.2 mg/kg/day) was given to the animals in Group 3 for seven days. On the seventh postoperative day, the animals were sacrificed …
Effects Of Acute Grayanotoxin-I Administrationon Hepatic And Renal Functions In Rats, Meral Aşçioğlu, Çi̇ğdem Özesmi̇, Paki̇ze Doğan, Fi̇ngen Öztürk
Effects Of Acute Grayanotoxin-I Administrationon Hepatic And Renal Functions In Rats, Meral Aşçioğlu, Çi̇ğdem Özesmi̇, Paki̇ze Doğan, Fi̇ngen Öztürk
Turkish Journal of Medical Sciences
The effects of acute Grayanotoxin-I (GTX-I) administration on hepatic and renal functions in rats were investigated. GTX-I was administrated to the animals of groups 1, 2 and 3 at a single i.p. dose of 1 mg/kg, 0.5 mg/kg and 0.25 mg/kg respectively, and group 4 (control) received i.p. saline (0.9 %) solution only. One hour following the administration of GTX-I or saline, urine analysis (leukocytes, urobilinogen, protein, pH, blood, ketone, glucose, nitrites) was performed and serum was evaluated for activities of glutamic pyruvic transaminase (GPT), \gamma-glutamyl transferase (\gamma-GT) and isoenzymes of lactate dehydrogenase (LDH) (as a percentage of total LDH …
Serum Antiotensin Converting Enzyme Activity In Streptozotocin-Induced Diabetic Rats, Mustafa Vakur Bor, Esra Seval Elmali, Ni̇lgün Altan
Serum Antiotensin Converting Enzyme Activity In Streptozotocin-Induced Diabetic Rats, Mustafa Vakur Bor, Esra Seval Elmali, Ni̇lgün Altan
Turkish Journal of Medical Sciences
No abstract provided.
Hvj-Liposome-Mediated Gene Transfer To Healing Rat Meniscal Tissue, İlhan Özkan, Norimasa Nakamura, Konsei Shino, Takashi Natsu-Ume, Tetsuya Tomita, Yasufumi Kaneda, Takahiro Ochi
Hvj-Liposome-Mediated Gene Transfer To Healing Rat Meniscal Tissue, İlhan Özkan, Norimasa Nakamura, Konsei Shino, Takashi Natsu-Ume, Tetsuya Tomita, Yasufumi Kaneda, Takahiro Ochi
Turkish Journal of Medical Sciences
The success rate of a repaired torn meniscus is not more than 70%. Gene transfer to healing soft tissues appears to be a feasible method for manipulating the healing process. In an attempt to evaluate the feasibility of gene transfer to meniscal tissue we tried to transfer a reporter gene ( Echerichia coli, b-galactosidase gene) by using HVJ-liposome mediated gene transfer. After performing complete radial tear on the medial meniscus of fifty 14-week-old male Wistar rats, HVJ-liposomes with DNA were injected into the femoral artery of 15 rats and into the knee joint of the other 15 rats. HVJ- liposomes …
The Radioprotective Effect Of Vitamins C, E And Vitamin E + Glutathione On The Small Intestine And The Thyroid Gland In Rats Irradiated With X- Rays, Cemi̇l Sert, M. Sali̇h Çeli̇k, Zülküf Akdağ, M. Aydin Ketani̇, Yusuf Nergi̇z
The Radioprotective Effect Of Vitamins C, E And Vitamin E + Glutathione On The Small Intestine And The Thyroid Gland In Rats Irradiated With X- Rays, Cemi̇l Sert, M. Sali̇h Çeli̇k, Zülküf Akdağ, M. Aydin Ketani̇, Yusuf Nergi̇z
Turkish Journal of Medical Sciences
This investigation was carried out in order to determine the protective effects of long term administration at supraphysiologi- cal doses of vitamin E, vitamin C and a compound of vitamin E + glutathione against damage induced by free radicals produced by ionizing radiation. Five groups of 8-10-week-old Wistar albino rats were used in the study. Group I was the sham group and Group II was the radiation group (i.e. radiation alone). The rats in Group III were given a daily dose of 400 mg/kg of vit. C for one month. The rats in Group IV were given a daily dose …
Antioxidant And Hepatoprotective Activity Of Vitamin E And Egb 761 In Experimental Endotoxemic Rats, Ömer Coşkun, Bi̇rkan Yakan, Emi̇n Öztaş, Şaban Sezen, Ali̇ A. Günaydin
Antioxidant And Hepatoprotective Activity Of Vitamin E And Egb 761 In Experimental Endotoxemic Rats, Ömer Coşkun, Bi̇rkan Yakan, Emi̇n Öztaş, Şaban Sezen, Ali̇ A. Günaydin
Turkish Journal of Medical Sciences
In this experimental study, we investigated whether vitamin E and EGb 761 have any influence on endotoxemic rats and liver histopathology. Forty rats were divided into four groups of 10 animals in each group. The control rats were untreated and comprised group 1. Two ml serum was applied to the rats intraperitoneally (i.p.) in group 2, and then 0.5 ml endotoxin solution ( E. Coli 0:157:H7, 10 9 bacteria/ml) was given to the same group two hours later. Not only endotoxin solution but also vitamin E (600 mg/kg) was given to the rats in group 3. Endotoxin solution and EGb …
Contralateral White Noise-Induced Enhancement In The Guinea Pigõs Mlr: A Possible Link To Direc- Tional Hearing, Cüneyt Göksoy, Rezzan Utkuçal
Contralateral White Noise-Induced Enhancement In The Guinea Pigõs Mlr: A Possible Link To Direc- Tional Hearing, Cüneyt Göksoy, Rezzan Utkuçal
Turkish Journal of Medical Sciences
The evoked potential components in a time window of 10-50 ms following an acoustic stimulus are called middle latency responses (MLRs). It is known that an amplitude enlargement occurs in guinea pig MLRs to monaural clicks when continuous white noise is applied to the other ear. This study was undertaken to see whether this enlargement is due simply to an overall, generalised effect of contralateral white noise (WN), or whether it may have some connection to directional hearing. Recordings were made from chronic guinea pig preparations with epidural electrodes in the temporal regions. Parallel to the results in the literature, …
Quinolone Arthropathy Induced By Ofloxacin In Juvenile Rats: A Light Microscopic Study, İlki̇n Çavuşoğlu, Zeynep Kahveci̇, Semi̇ha Noyan, Zehra Mi̇nbay
Quinolone Arthropathy Induced By Ofloxacin In Juvenile Rats: A Light Microscopic Study, İlki̇n Çavuşoğlu, Zeynep Kahveci̇, Semi̇ha Noyan, Zehra Mi̇nbay
Turkish Journal of Medical Sciences
This study was conducted to examine the development, progression and reversibility of cartilage lesions in juvenile rats that had been given ofloxacin, a fluoroquinolone. Four-week-old rats were treated with an oral dose of 900 mg/kg/day of ofloxacin for 7 days. The animals were sacrificed at different (1 st^day, 1 st^week, 2^nd week, 4 th^ week, 8 th^ week, 12 th^ week, 16 th^ week) after the completion of the administration and the knee joints were prepared for light microscopic analysis. The lesions were demonstrated in the articular cartilage of all the animals. Acellular, oedematous matrix areas, and cavity formations were …
Role Of End-Tidal Co_2 Monitoring In Patients Intubated And Resuscitated In The Emergency Department, Özgür Karcioğlu, Yasemi̇n Karcioğlu
Role Of End-Tidal Co_2 Monitoring In Patients Intubated And Resuscitated In The Emergency Department, Özgür Karcioğlu, Yasemi̇n Karcioğlu
Turkish Journal of Medical Sciences
Objective: We examined the reliability of end-tidal CO_2 (ETCO_2 ) level in predicting mortality after endotracheal intubation in emergency situations. Methods: In this prospective study, the reliability of ETCO_2 monitoring in the emergency setting as a useful predictor of outcome was investigated in 36 adult patients with pending cardiopulmonary collapse. The cardiopulmonary resuscitation (CPR) procedure was performed as usual and the cardiac rhythm, arterial O_2 saturation, non- invasive blood pressure and ETCO_2 levels were continuously monitored in all the patients. Results: Patients with an ETCO_2 concentration below 0.5% had significantly lower rates of survival. The sensitivity and specificity values of …
Lamotrigine Treatment In Childhood Drug-Resistant Epilepsy, Nedret Uran, Gül Serdaroğlu, Şebnem Çalkavur, Erki̇n Serdaroğlu
Lamotrigine Treatment In Childhood Drug-Resistant Epilepsy, Nedret Uran, Gül Serdaroğlu, Şebnem Çalkavur, Erki̇n Serdaroğlu
Turkish Journal of Medical Sciences
Rationale: In this study the efficacy of Lamotrigine was evaluated in children with medically intractable epilepsy. Methods: 22 epileptic children, ranging between 4.2 years and 15 years of age (mean 9.3 years) were included in this study. Twelve (54.5%) were male and 10 (45.5%) were female. The seizure types were classified according to the International League Against Epilepsy criteria: simple partial seizures (8 cases), infantile spasms (4 cases), generalized tonic-clonic seizures (2 cases), tonic seizures (2 cases), complex partial seizure (2 cases), typical absence seizures (2 cases), myoclonic astatic seizures (1 case) and atypical absence seizures (1 case). The neurological …
High-Dose Intravenous Immunoglobulin Treatment In Intractable Childhood Epilepsy, Nedret Uran, Gül Serdaroğlu, Erki̇n Serdaroğlu, Sema Kalkan, Tuğrul Özcan
High-Dose Intravenous Immunoglobulin Treatment In Intractable Childhood Epilepsy, Nedret Uran, Gül Serdaroğlu, Erki̇n Serdaroğlu, Sema Kalkan, Tuğrul Özcan
Turkish Journal of Medical Sciences
Rationale: Intractable childhood epilepsy is characterised by convulsions, which are resistant to treatment with adequate dosage, combination and duration of appropriate anticonvulsant drugs. Many clinical and experimental studies support the role of the immune mechanism in the pathogenesis of childhood epilepsy. The purpose of the present study is to ascertain the possible efficacy of intravenous immunoglobulin in the treatment of intractable childhood epilepsy. Methods: The children aged 4-8 years suffering from intractable childhood epilepsy were treated with high-dose intravenous immunoglobulin (400 mg/kg) 5 times in the first week, on the 15th and 30th days. The treatments were repeated every 4 …
Effect Of Calcium, Magnesium, Sodium And Potassium Levels In Seminal Plasma Of Holstein Bulls On Spermatological Characters, Seyfetti̇n Gür, Eşref Demi̇rci̇
Effect Of Calcium, Magnesium, Sodium And Potassium Levels In Seminal Plasma Of Holstein Bulls On Spermatological Characters, Seyfetti̇n Gür, Eşref Demi̇rci̇
Turkish Journal of Veterinary & Animal Sciences
This study was conducted to investigate the levels calcium, magnesium, sodium and potassium in the seminal plasma of bulls, semen volume, sperm motility, sperm concentration and the correlation between these parametres. Five Holstein bulls constituted the material of this study. Twenty ejaculates were collected from each bull and the spermatological characteristics of these ejaculates were determined. Then, seminal plasma was separated from 3ml semen from each ejaculate by centrifugation at 1500g for 20 min at 4 °C. Calcium, magnesium, sodium and potassium concentrations in seminal plasma were determined by atomic absorption spectrophotometry. The average values for calcium, magnesium, sodium and …
Experimentally Developed Secondaryechinococcosis In Pleural And Peritoneal Cavitiesand The Utility Of Serological Tests During Thefollow Up, Kadi̇r Kazez, Mustafa Şahi̇n, Celaletti̇n Vatansev, Yücel Aritaş, Faruk Aksoy, Hüsametti̇n Vatansev
Experimentally Developed Secondaryechinococcosis In Pleural And Peritoneal Cavitiesand The Utility Of Serological Tests During Thefollow Up, Kadi̇r Kazez, Mustafa Şahi̇n, Celaletti̇n Vatansev, Yücel Aritaş, Faruk Aksoy, Hüsametti̇n Vatansev
Turkish Journal of Medical Sciences
Secondary echinococcosis is an important complication of hydatid disease and is not rare in the peritoneal cavity. However, the frequency of secondary hydatidosis in the pleural cavity is not very well known. This study was planned to elicit the frequency of secondary cyst development in the pleural cavity, and to compare this with secondary peritoneal hydatidosis. It was also intended to follow up cyst development by serological tests. Twelve white female Island rabbits were used. The mean weight of the rabbits was 2450±420 g. Cystic fluid containing protoscolex, hydatid sand and germinative membrane homogenate was injected via an 18 F …
Comparative Studies On The Production Performances Of Chios And Imroz Breeds Kept Under Semi-Intensive Conditionus Ii. Milk Production, Fleece Yields And Characteristics, Şebnem Gündal Çörekçi̇, Mehmet Evri̇m
Comparative Studies On The Production Performances Of Chios And Imroz Breeds Kept Under Semi-Intensive Conditionus Ii. Milk Production, Fleece Yields And Characteristics, Şebnem Gündal Çörekçi̇, Mehmet Evri̇m
Turkish Journal of Veterinary & Animal Sciences
This paper is the second part of a study carried out to reveal the comparative production performances and effect of some environmental factors on the production characteristics of Chios and Imroz ewes kept in a single flock under semi-intensive conditions. In this part of the study milk yields, lactation lengths and fleece weights and characteristics were considered. Mean lactation lengths and milk yield of Chios ewes were 203 days and 73.92 kg respectively; the comparative values for Imroz ewes were 223 days and 102.04 kg respectively. At the first shearing (6 months of age), average fleece weights of Chios and …
Distributions And Possible Roles Of Laminin, Fibronectin And Theirreceptor Subunits Integrin \Beta4 And \Alpha5 In Remodelling Of Extracellularmatrix During Decidualization In Rats, Ümi̇t Ali̇ Kayişli, Mevlüt Asar, Ramazan Demi̇r
Distributions And Possible Roles Of Laminin, Fibronectin And Theirreceptor Subunits Integrin \Beta4 And \Alpha5 In Remodelling Of Extracellularmatrix During Decidualization In Rats, Ümi̇t Ali̇ Kayişli, Mevlüt Asar, Ramazan Demi̇r
Turkish Journal of Biology
In the endometrium preparing for pregnancy, the stromal matrix components of the cells and their products begin structural differentiation due to endometrial receptivity. According to the hypothesis that 'extracellular matrix (ECM) proteins and adhesion molecules take roles in the structural differentiation as a result of endometrial decidualization', our aim was to determine the roles of ECM molecules laminin, fibronectin and adhesion proteins integrin \alpha5 and \beta4 in the decidulization and implantation by examining the emergence and changing distribution of these proteins. In this study, five experimental groups, consisting of 40 pregnant animals on pregnancy days 4-8, were used. Paraffin tissue …
The Possibility Of Using Crustacean Waste Products(Cwp) On Rainbow Trout ( Oncorhynchus Mykiss)Feeding, Yeşi̇m Özoğul
The Possibility Of Using Crustacean Waste Products(Cwp) On Rainbow Trout ( Oncorhynchus Mykiss)Feeding, Yeşi̇m Özoğul
Turkish Journal of Biology
Crustacean waste product (CWP) generated from the fishing industry could be used in diets for rainbow trout as an alternative animal protein. Some experiments have been undertaken with penaid species, showing that it is possible to partially replace fish meal with CWP in penaid feeds. This study has been designed to assess whether CWP could be used to partially replace fish meal in diets for rainbow trout. The results show that CWP improved the digestibility of the diet, yielding the highest performance, and also that the addition of large amounts of CWP to a low-protein diet did not depress appetite. …
Effects Of Different Media, Type And Concentrations Of Auxin On Callus Induction And Plant Regeneration From Young Inflorescences Of Yellow Bluestem (Bothriochloa Ischaemum(L.) Keng), Ersi̇n Can, Rüştü Hati̇poğlu
Effects Of Different Media, Type And Concentrations Of Auxin On Callus Induction And Plant Regeneration From Young Inflorescences Of Yellow Bluestem (Bothriochloa Ischaemum(L.) Keng), Ersi̇n Can, Rüştü Hati̇poğlu
Turkish Journal of Agriculture and Forestry
This study was conducted to determine the effects of different media, auxin types and concentrations on callus induction and plant regeneration from young inflorescences of 15 ecotypes of yellow bluestem ( Bothriochloa ischaemum). The young inflorescences were cultured on two different basal media (LS and SH) containing different concentrations (2, 4, 6, and 8 mg/l) of two different auxins (2, 4-D and Dicamba). The results showed that the ecotypes were significantly different from each other in callus induction rate, callus weight per dish and regenerate number per inflorescence segment. Depending on the ecotypes, mean callus induction rate varied from 9.7% …
Macrophyte-Dominated Clearwater State Of Lake Mogan, S. Levent Burnak, Meryem Bekli̇oğlu
Macrophyte-Dominated Clearwater State Of Lake Mogan, S. Levent Burnak, Meryem Bekli̇oğlu
Turkish Journal of Zoology
In this study, the water chemistry and zooplankton community of Lake Mogan studied between March 1997 and April 1998. Small-scale industries, crop-farming, urban settlement of the municipality of Gölbaşı with the untreated raw sewage effluent and recreational activities are examples of the human impact within the catchment and the lake, leading to high loading of DIN and TP into the lake via the inflows. However, the natural wetland with the dense reedbeds (Çölovası or Çökek Bataklığı), located on the southern end of the lake, appear to act as a sink for these nutrients. Therefore, the in-lake concentartions of DIN and …
Transfer Of A \Beta-Glucuronidase Reporter Gene To Sugarbeet (Beta Vulgaris L.) Via Microprojectile Bombardment, Sertaç Önde, Melahat Bi̇rsi̇n, Mustafa Yildiz, Cengi̇z Sancak, Murat Özgen
Transfer Of A \Beta-Glucuronidase Reporter Gene To Sugarbeet (Beta Vulgaris L.) Via Microprojectile Bombardment, Sertaç Önde, Melahat Bi̇rsi̇n, Mustafa Yildiz, Cengi̇z Sancak, Murat Özgen
Turkish Journal of Agriculture and Forestry
For the transfer of a \beta -Glucuronidase (GUS) reporter gene to sugarbeet (Beta vulgaris L.) callus and leaf explants by microprojectile bombardment, various rupture disk pressures and sample plate distances were tested. By coating the pBI221.23 DNA construct over the gold particles, bombardments were carried out by the DuPont PDS-1000/He system and the results clearly indicated the superiority of leaf explants over the callus structures as targets. The sample plate distances affected the distribution pattern of the particles and the cells expressing the GUS reporter gene were noted to be aggregated in short distances whereas longer distance shots yielded better …