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Evaluation Of Different Stocking Densities On Fattening Performance, Slaughter, Carcass, Meat Quality Characteristics, And Fatty Acid Composition In New Zealand Rabbits, Büşra Yaranoğlu, Mustafa Hi̇lmi̇ Yaranoğlu, Sali̇ha Uysal, Adnan Adi̇l Hi̇şmi̇oğullari
Evaluation Of Different Stocking Densities On Fattening Performance, Slaughter, Carcass, Meat Quality Characteristics, And Fatty Acid Composition In New Zealand Rabbits, Büşra Yaranoğlu, Mustafa Hi̇lmi̇ Yaranoğlu, Sali̇ha Uysal, Adnan Adi̇l Hi̇şmi̇oğullari
Turkish Journal of Veterinary & Animal Sciences
The aim of the research was to investigate the effects of different stocking densities on fattening performance, slaughter, carcass, meat quality characteristics, and fatty acid composition in New Zealand rabbits raised in cage conditions and also determine the ideal housing frequency so that yields were not adversely affected. In the study, 36 New Zealand rabbits were used. After weaning, the fattening was started and rabbits were put into cages at different stocking densities as 1 rabbit/cage, 2 rabbits/cage, and 3 rabbits/ cage. The live weight of rabbits and feed consumption data were taken every week. At the end of 8 …
A Review With Updated Perspectives On In Vitro And In Vivo Wound Healing Models, Murni Nazira Sarian, Nabilah Zulkefli, Shazeli Zain, Sandra Maniam, Sharida Fakurazi
A Review With Updated Perspectives On In Vitro And In Vivo Wound Healing Models, Murni Nazira Sarian, Nabilah Zulkefli, Shazeli Zain, Sandra Maniam, Sharida Fakurazi
Turkish Journal of Biology
A skin wound or perforation triggers a series of homeostatic reactions to safeguard internal organs from invasion by pathogens or other substances that could damage body tissues. An injury may occasionally heal quickly, leading to the closure of the skin's structure. Healing from chronic wounds takes a long time. Although many treatment options are available to manage wound healing, an unmet therapy need remains because of the complexity of the processes and the other factors involved. It is crucial to conduct consistent research on novel therapeutic approaches to find an effective healing agent. Therefore, this work aims to cover various …
Antioxidant Potential Of Nanomaterials, David Gonzalez Flores, Javier Espino, Jose A. Pariente
Antioxidant Potential Of Nanomaterials, David Gonzalez Flores, Javier Espino, Jose A. Pariente
Turkish Journal of Biology
Background/aim: The novel field of nanomaterials allows infinite possibilities in order to create antioxidant therapies. The present review is aimed to describe the state of art concerning on nanomaterials and their effects on reactive oxygen species (ROS) production. A wide range of nanoparticles has been designed for this purpose, and each one possesses some particular characteristics which allow these significant antioxidant results. Several in vivo and in vitro works state the ability of these nanoparticles to mimic the redox systems of the cells, and thus, the potential role of nanoparticles as antioxidant treatment for several diseases. Materials and methods: This …
Antileukemic Potential Of Nile Blue-Mediated Photodynamic Therapy On Hl60 Human Myeloid Leukemia Cells, Serçi̇n Özlem Çalişkan, Aynur Karadağ, Bariş Uzunok, Numan Taşpinar, Berna Akin, Meti̇n Çalişkan, Rahşan Ilikçi Sağkan
Antileukemic Potential Of Nile Blue-Mediated Photodynamic Therapy On Hl60 Human Myeloid Leukemia Cells, Serçi̇n Özlem Çalişkan, Aynur Karadağ, Bariş Uzunok, Numan Taşpinar, Berna Akin, Meti̇n Çalişkan, Rahşan Ilikçi Sağkan
Turkish Journal of Biology
Background/aim: Photodynamic therapy (PDT) has received great attention over the past decade in the treatment of diseases such as leukemia which is a cancer of the blood and bone marrow cells that causes a significant number of deaths worldwide. In this study, it was aimed to investigate the effects of Nile blue-mediated PDT (NB-mediated PDT) on HL60 cells. Materials and methods: The effect of NB-mediated PDT on cell proliferation was evaluated with cell volume analysis using flow cytometry at 24 h. Cell apoptosis, ROS production, mitochondrial membrane potential, and cell cycle analysis were evaluated using annexin V-FITC, H2 DCFDA, JC-1, …
Targeting Of Notch, Il-1, And Leptin Has Therapeutic Potential In Xenograft Colorectal Cancer, Rumeysa Özyurt, Ni̇lüfer Erkasap, Mete Özkurt, Serdar Mustafa Erkasap, Konstanti̇nos Di̇mas, Ayşe Çakir Gündoğdu, Engi̇n Ulukaya
Targeting Of Notch, Il-1, And Leptin Has Therapeutic Potential In Xenograft Colorectal Cancer, Rumeysa Özyurt, Ni̇lüfer Erkasap, Mete Özkurt, Serdar Mustafa Erkasap, Konstanti̇nos Di̇mas, Ayşe Çakir Gündoğdu, Engi̇n Ulukaya
Turkish Journal of Biology
Background/aim: Colorectal cancer (CRC) is a fatal malignancy type and its occurence still needs to be explored mechanistically. Notch, IL-1, and leptin crosstalk is reported to play a role in the proliferation, migration, and expression of proangiogenic molecules. In this study, we aimed to investigate the effect of inhibition of Notch, IL-1, and leptin on CRC. Materials and methods: To generate colorectal cancer tumor xenografts, 1 × 107 cells from exponentially growing cultures of HCT15 cells were injected subcutaneously, at the axillary region of the left and right rear flanks of forty NOD.CB17-Prkdcscid/J (NOD/SCID) female mice. The mice were then …
Soloxolone Methyl Induces Apoptosis And Oxidative/Er Stress In Breast Cancer Cells And Target Cancer Stem Cell Population, Eli̇f Ertürk, Oğuzhan Akgün, Yaren Yildiz, Pinar Kalkan, Oksana V. Salomatina, Nariman F. Salakhutdinov, Engi̇n Ulukaya, Ferda Ari
Soloxolone Methyl Induces Apoptosis And Oxidative/Er Stress In Breast Cancer Cells And Target Cancer Stem Cell Population, Eli̇f Ertürk, Oğuzhan Akgün, Yaren Yildiz, Pinar Kalkan, Oksana V. Salomatina, Nariman F. Salakhutdinov, Engi̇n Ulukaya, Ferda Ari
Turkish Journal of Biology
One of the most prevalent malignancies in women and one of the leading causes of cancer-related death is breast cancer. There is a need for new treatment approaches and drugs for breast cancer. Many studies show the high potential of triterpene compounds and their semisynthetic derivatives as anticancer agents due to their ability to induce apoptosis and suppress tumorigenesis. The effects of soloxolone methyl (SM), a semisynthetic derivative of 18-H-glycyrrhetinic acid, on the cytotoxicity and apoptosis of human breast cancer cell line (T-47D) and cancer stem cell (CSCs) population (mammospheres; CD44+/CD24-antigen) derived from breast cancer cells, were examined in this …
Reconstructing Dynamic Human Shapes From Sparse Silhouettes Via Latent Space Optimization Of Parametric Shape Models, Kanika Singla, Parma Nand
Reconstructing Dynamic Human Shapes From Sparse Silhouettes Via Latent Space Optimization Of Parametric Shape Models, Kanika Singla, Parma Nand
Turkish Journal of Electrical Engineering and Computer Sciences
The problem of dynamic 3D reconstruction has gained popularity over the last few years with most approaches relying on data driven learning and optimization methods. However this is quite a challenging task because of the need for tracking different features in both space and time?that too of deformable objects-where such robust tracking may not always be possible. A common way to better ground the problem is by using some forms of regularizations primarily on the shape representations. Over the years, mesh-based linear blend skinning models have been the standard for fitting templates of humans to the observed time series data …
Generalized Elliptical Quaternions With Some Applications, Harun Bariş Çolakoğlu, Mustafa Özdemi̇r
Generalized Elliptical Quaternions With Some Applications, Harun Bariş Çolakoğlu, Mustafa Özdemi̇r
Turkish Journal of Mathematics
In this article, quaternions, which is a preferred and elegant method for expressing spherical rotations, are generalized with the help of generalized scalar product spaces, and elliptical rotations on any given ellipsoid are examined by them. To this end, firstly, we define the generalized elliptical scalar product space which accepts the given ellipsoid as a sphere and determines skew symmetric matrices, and the generalized vector product related to this scalar product space. Then we define the generalized elliptical quaternions by using these notions. Finally, elliptical rotations on any ellipsoid in the space are examined by using the unit generalized elliptical …
Determination Of Cadmium And/Or Drought Stress Effects On Some Plant Phytohormone Contents And Hormone Gene Expressions In Bean (Phaseolus Vulgaris L), Melek Eki̇nci̇, Ertan Yildirim, Güleray Ağar, Esra Arslan Yüksel, Murat Aydin, Selda Örs, Razi̇ye Kul
Determination Of Cadmium And/Or Drought Stress Effects On Some Plant Phytohormone Contents And Hormone Gene Expressions In Bean (Phaseolus Vulgaris L), Melek Eki̇nci̇, Ertan Yildirim, Güleray Ağar, Esra Arslan Yüksel, Murat Aydin, Selda Örs, Razi̇ye Kul
Turkish Journal of Agriculture and Forestry
Plants can sometimes be under the influence of more than one stress factor. In this case, combined stress factors can cause different responses in plants. In this study, the phytohormonal activity and hormone gene expressions of beans (Phaseolus vulgaris L.) were investigated in different drought levels and soils with different levels of cadmium accumulation. Plants were grown at 4 different cadmium (Cd) levels (Cd: 0, Cd1: 100, Cd2: 150, and Cd3: 200 mg kg$^{-1}$) and 3 irrigation levels (D0: 100%, D1: 75%, and D2: 50% of field capacity). Abscisic acid (ABA), indole acetic acid (IAA), gibberellic acid (GA), salicylic acid …
Early Assessment Of Extremity Compartment Syndrome By Biochemical Markers In A Rat Model, Ahmet Yildirim, İbrahi̇m Özkan Önal, Zeli̇ha Esi̇n Çeli̇k, Hüsametti̇n Vatansev, Esra Paydaş Hataysal
Early Assessment Of Extremity Compartment Syndrome By Biochemical Markers In A Rat Model, Ahmet Yildirim, İbrahi̇m Özkan Önal, Zeli̇ha Esi̇n Çeli̇k, Hüsametti̇n Vatansev, Esra Paydaş Hataysal
Turkish Journal of Medical Sciences
Background/aim: This experimental study aimed to define a biochemical marker that will enable early diagnosis of acute compartment syndrome (ACS) of extremities, a mortal condition that occurs due to trauma. Materials and methods: A total of 15 Wistar rats were included in the study in which saline infusion technique, a clinically compatible ACS model, was applied. After the rats were anesthetized with ketamine-xylazine, the in-compartment pressure of the hind limb was slowly increased with saline delivered through the angiocatheter, and after reaching the target compartment pressure, the pressure level was kept with a rubber tourniquet. The in-compartment pressure level was …
Effect Of Crocin And Losartan On Biochemical Parameters And Genes Expression Of Frmd3 And Bmp7 In Diabetic Rats, Yaser Mohammadi, Mohammad Zangooei, Fatemeh Salmani, Azam Rezaei Farimani
Effect Of Crocin And Losartan On Biochemical Parameters And Genes Expression Of Frmd3 And Bmp7 In Diabetic Rats, Yaser Mohammadi, Mohammad Zangooei, Fatemeh Salmani, Azam Rezaei Farimani
Turkish Journal of Medical Sciences
Background/aim: Diabetes is a multifactorial and growing disease, one of the severe complications of which is diabetic nephropathy (DN), which is the most common cause of chronic renal failure. FERM domain containing 3 (FRMD3) is responsible for maintaining the shape and integrity of nephron cells, and bone morphogenetic protein 7 (BMP7) helps maintain function and reduce kidney damage. This study aimed to evaluate the effect of crocin and losartan on biochemical parameters and the expression of FRMD3 and BMP7 genes in streptozotocin (STZ)-induced diabetic rats. Materials and methods: Forty male Wistar rats were randomly divided into five experimental groups as …
Effects Of Recurrent Ketamine Exposure On Brain Histopathology In Juvenile Rats, Ayşe Hande Arpaci, Süheyla Esra Özkoçer, Emel Güneş, Çi̇ğdem Elmas, Berri̇n Işik
Effects Of Recurrent Ketamine Exposure On Brain Histopathology In Juvenile Rats, Ayşe Hande Arpaci, Süheyla Esra Özkoçer, Emel Güneş, Çi̇ğdem Elmas, Berri̇n Işik
Turkish Journal of Medical Sciences
Background/aim: Ketamine (KET) is a commonly used anesthetic agent. However, several previous studies reported that KET leads to neuronal damage in neurodevelopmental stages and has neuroprotective effects. The present experimental study aimed to determine the undesirable histopathological effects of KET in the cerebral cortex, striatum, and hippocampus after recurrent KET administration in juvenile rats. Materials and methods: After ethical approval was obtained, 32 juvenile male Wistar Albino rats were randomized into four groups: 1 mg/kg serum saline intraperitoneally (i.p.), 5 mg/kg KET i.p., 20 mg/kg KET i.p., and 50 mg/kg KET i.p. KET was administered for three consecutive days at …
Investigation Of Taurine And Aqueous Garlic Extract Diet Supplementation Effect On The Healing Of Rat Osteoporotic Fractures, Mesut Misirlioğlu, İzzet Bi̇ngöl, Coşkun Genç, Ayli̇n Akbulut, Mert Ocak, Nezi̇ha Yağmur Di̇ker, Ahmet Özmeri̇ç, Gökhan Koca, Meli̇ke Bahçeci̇tapar, Mehmet Şeneş, Ayşegül Firat, Fevzi̇ye Fi̇gen Kaymaz, Hakan Hamdi̇ Çeli̇k, İffet İrem Çankaya, Meli̇ha Korkmaz
Investigation Of Taurine And Aqueous Garlic Extract Diet Supplementation Effect On The Healing Of Rat Osteoporotic Fractures, Mesut Misirlioğlu, İzzet Bi̇ngöl, Coşkun Genç, Ayli̇n Akbulut, Mert Ocak, Nezi̇ha Yağmur Di̇ker, Ahmet Özmeri̇ç, Gökhan Koca, Meli̇ke Bahçeci̇tapar, Mehmet Şeneş, Ayşegül Firat, Fevzi̇ye Fi̇gen Kaymaz, Hakan Hamdi̇ Çeli̇k, İffet İrem Çankaya, Meli̇ha Korkmaz
Turkish Journal of Medical Sciences
Background/aim: We have evaluated the effects of taurine and aqueous garlic extract (AGE) as a dietary supplement on osteoporotic fracture (OPF) healing in the ovariectomized rat femur fracture model. Materials and methods: In this experimental animal study,twenty-four osteoporosis-remodeled female Wistar albino rats were randomly divided into 3 groups (n: 8) according to their supplemented diet; control, taurine, and AGE groups. Unilateral femur middiaphysis mini-open osteotomy was stabilized with Kirschner wires. Six weeks after osteotomy, the rats were sacrificed before the femurs were harvested and OPF healing was evaluated with biochemical, histologic, microcomputed-tomography, and scintigraphic methods. Results: As an indicator of …
The Role Of Curcumin Against Paclitaxel-Induced Oxidative Stress And Dna Damage In Testes Of Adult Male Rats, Esra Balcioğlu, Özge Göktepe, Fazi̇le Cantürk Tan, Pinar Bi̇lgi̇ci̇, Bi̇rkan Yakan, Sai̇m Özdamar
The Role Of Curcumin Against Paclitaxel-Induced Oxidative Stress And Dna Damage In Testes Of Adult Male Rats, Esra Balcioğlu, Özge Göktepe, Fazi̇le Cantürk Tan, Pinar Bi̇lgi̇ci̇, Bi̇rkan Yakan, Sai̇m Özdamar
Turkish Journal of Medical Sciences
Background/aim: Paclitaxel is a widely used drug for the treatment of cancer, but it possesses toxic effects on male reproductive system. Administering paclitaxel with an antioxidant has become a strategy for preventing the side effects of paclitaxel. Although curcumin is an antioxidant, data concerning the effect of curcumin on paclitaxel-induced testis tissue are lacking. The present study was established to examine the protective impact of curcumin against testicular damage induced by paclitaxel. Materials and methods: In the study, 40 Wistar albino male rats were used and randomly divided into 4 groups (n:10). The control group received only saline solution; the …
An Experimental Study: The Effect Of S. Boulardii On Abemaciclib-Induced Diarrhea, İbrahi̇m Ethem Cakcak, Yusuf Emre Ayti̇n, Sezi̇n Sayin, Ahmet Küçükarda, Ali̇ Gökyer, İvo Gökmen, Erkan Özcan, Selçuk Korkmaz, Ebru Taşteki̇n, İrfan Çi̇çi̇n
An Experimental Study: The Effect Of S. Boulardii On Abemaciclib-Induced Diarrhea, İbrahi̇m Ethem Cakcak, Yusuf Emre Ayti̇n, Sezi̇n Sayin, Ahmet Küçükarda, Ali̇ Gökyer, İvo Gökmen, Erkan Özcan, Selçuk Korkmaz, Ebru Taşteki̇n, İrfan Çi̇çi̇n
Turkish Journal of Medical Sciences
Background/aim: In our study, we aimed to investigate the protective effects of Saccharomyces boulardii on abemaciclib-induced diarrhea model, which is a commonly used drug in breast cancer. Materials and methods: Thirty rats were divided into 3 groups as control (Group 1), abemaciclib (Group 2), and abemaciclib + Saccharomyces boulardii (Group 3) groups. The clinical status, body weight, and defecation status were monitored daily. At the end of the 15-day experiment period, the rats were killed with high-dose anesthesia and the resected small intestine segments were evaluated histopathologically. Lesions were classified according to thickening of the villus, inflammation and edema of …
Evaluation Of The Effects Of Three Natural Products And A Hemostatic Agent On Wound Healing: An Experimental Study, Ayşe Çeli̇k Yilmaz, Di̇lek Aygi̇n
Evaluation Of The Effects Of Three Natural Products And A Hemostatic Agent On Wound Healing: An Experimental Study, Ayşe Çeli̇k Yilmaz, Di̇lek Aygi̇n
Turkish Journal of Medical Sciences
Background/aim: People have used many natural materials such as plant leaves, roots, liquids derived from plants, and animal products to treat wounds throughout history. It can be said that the research on wound care in recent years have focused on traditional and natural products again. This study aimed to investigate the effects of sweetgum oil, propolis, silk protein, and Ankaferd Blood Stopper (ABS) on wound healing in an experimental excisional wound model. Materials and methods: Including 36 Balb/c inbreed mice in the study were divided equally into four groups. Two circular excisional wounds were created on the dorsal skin of …
Postnatal Surgery For Myelomeningocele In Neonates: Neurodevelopmental Outcomes, Melek Akar, Gülşah Çeti̇n, Mi̇ne İnal, Mehmet Helvaci, Ni̇hal Olgaç Dündar, Firat Ergi̇n, Özgün Uygur, Si̇nem Akbay, Nai̇l Özdemi̇r, Meltem Koyuncu Arslan, Mehmet Yekta Öncel
Postnatal Surgery For Myelomeningocele In Neonates: Neurodevelopmental Outcomes, Melek Akar, Gülşah Çeti̇n, Mi̇ne İnal, Mehmet Helvaci, Ni̇hal Olgaç Dündar, Firat Ergi̇n, Özgün Uygur, Si̇nem Akbay, Nai̇l Özdemi̇r, Meltem Koyuncu Arslan, Mehmet Yekta Öncel
Turkish Journal of Medical Sciences
Background/aim: The study aims to evaluate the neurodevelopmental outcomes of neonates with myelomeningocele (MMC) operated in the postnatal period. Materials and methods: This is a prospective follow-up study in a tertiary neonatal intensive care unit. Neurodevelopmental outcomes of term neonates operated for MMC and healthy term newborns were compared with the Bayley Scales of Infant and Toddler Development -Third Edition (BSID III) at 12-18 months. Results: A total of 57 cases were included in the study (patient group = 27; control group = 30). Demographic data between the groups were similar. Cognitive, linguistic, and motor composite scores of the patient …
Transbronchial Lung Cryobiopsy For The Diagnosis Of Diffuse Parenchymal Lung Disease: Pitfalls And Challenges, A Single Center Experience, Kemal Can Tertemi̇z, Ayli̇n Özgen Alpaydin, Nurcan Güler, Volkan Karaçam, Duygu Gürel, Naci̇ye Si̇nem Gezer
Transbronchial Lung Cryobiopsy For The Diagnosis Of Diffuse Parenchymal Lung Disease: Pitfalls And Challenges, A Single Center Experience, Kemal Can Tertemi̇z, Ayli̇n Özgen Alpaydin, Nurcan Güler, Volkan Karaçam, Duygu Gürel, Naci̇ye Si̇nem Gezer
Turkish Journal of Medical Sciences
Background/aim: Transbronchial lung cryobiopsy (TBLC) is a minimally invasive technique of the diagnosis of diffuse parenchymal lung diseases (DPLD). The aim of this study is to determine the clinical-radiological and histopathological characteristics of patients in whom cryobiopsy contributes to the diagnosis. Materials and methods: In this retrospective study, we searched for the medical records of patients who underwent TBLC from July 2015 to March 2020 at the pulmonology department of our university hospital clinic. Radiological images were evaluated by a chest radiologist experienced in DPLD. Prediagnosis was indicated by clinical-radiological findings. The final diagnosis was determined by the contribution of …
Can Amniotic Fluid Protect Developing Fetal Lungs Against The Harmful Effects Of Oxidative Stress?, Levent Korkmaz, Cumali̇ Alan, İsmai̇l Topal, Mahi̇r Tayfur, Ali̇seydi̇ Bozkurt, Cebrai̇l Gürsul, Osman Baştuğ
Can Amniotic Fluid Protect Developing Fetal Lungs Against The Harmful Effects Of Oxidative Stress?, Levent Korkmaz, Cumali̇ Alan, İsmai̇l Topal, Mahi̇r Tayfur, Ali̇seydi̇ Bozkurt, Cebrai̇l Gürsul, Osman Baştuğ
Turkish Journal of Medical Sciences
Background/aim: Preterm births cause fetuses to be born without completing the development of their organs. Due to this undesirable situation, it is the pulmonary tissue which has to be most exposed to harmful effects of extrauterine environment. Early disappearance of the prophylactic and constructive effects of amniotic fluid (AF) on developing tissues, such as pulmonary tissue, facilitates the formation of pulmonary morbidities resulting from oxygen. Setting out from this knowledge, we wanted, in addition to assessing the beneficent effects of AF on pulmonary tissue, to study the importance of AF in morbidities of this tissue thought to originate from oxygen. …
Decreased Circulating Microrna-21 And Microrna-143 Are Associated To Pulmonary Hypertension, Zekeri̇ya Düzgün, Lati̇fe Meral Kayikçioğlu, Çağdaş Aktan, Buşra Bara, Fatma Zuhal Eroğlu, Burcu Yağmur, Vi̇ldan Bozok Çeti̇ntaş, Meli̇ke Bayindir, Sanem Nalbantgi̇l, Asli Teti̇k Vardarli
Decreased Circulating Microrna-21 And Microrna-143 Are Associated To Pulmonary Hypertension, Zekeri̇ya Düzgün, Lati̇fe Meral Kayikçioğlu, Çağdaş Aktan, Buşra Bara, Fatma Zuhal Eroğlu, Burcu Yağmur, Vi̇ldan Bozok Çeti̇ntaş, Meli̇ke Bayindir, Sanem Nalbantgi̇l, Asli Teti̇k Vardarli
Turkish Journal of Medical Sciences
Background/aim: Pulmonary arterial hypertension (PAH) is characterized by maladaptation of pulmonary vasculature which is leading to right ventricular hypertrophy and heart failure. miRNAs play a crucial role in the regulation of many diseases such as viral infection, cancer, cardiovascular diseases, and pulmonary hypertension (PH). In this study, we aimed to investigate the expression pattern of eight human plasma miRNAs (hsa-miR-21-3p, hsa-miR-143- 3p, hsa-miR-138-5p, hsa-miR-145-3p, hsa-miR-190a, hsa-miR-204-3p, hsamiR-206, hsa-miR-210-3p) in mild-to-severe PH patients and healthy controls. Materials and methods: miRNAs were extracted from the peripheral plasma of the PH patients (n: 44) and healthy individuals (n: 30) by using the miRNA …
The Impact Of Antiphospholipid Antibodies In Takayasu Arteritis, Esra Firat Şentürk, Abdulsamet Erden, Alper Sari, Berkan Armağan, Levent Kiliç, Umut Kalyoncu, Ömer Karadağ, Şazi̇ye Şule Apraş Bi̇lgen, Sedat Ki̇raz, Ali̇ İhsan Ertenli̇, Ali̇ Akdoğan
The Impact Of Antiphospholipid Antibodies In Takayasu Arteritis, Esra Firat Şentürk, Abdulsamet Erden, Alper Sari, Berkan Armağan, Levent Kiliç, Umut Kalyoncu, Ömer Karadağ, Şazi̇ye Şule Apraş Bi̇lgen, Sedat Ki̇raz, Ali̇ İhsan Ertenli̇, Ali̇ Akdoğan
Turkish Journal of Medical Sciences
Background/aim: The significance of antiphospholipid antibodies (aPL) is controversial in Takayasu arteritis (TA). This study was conducted to explore the frequency of aPL and their association with disease-related complications in TA. Materials and methods: This cross-sectional study was conducted to investigate the presence of anti-cardiolipin (aCL), anti-beta 2 glycoprotein- 1(aß2G1) antibodies, and lupus anticoagulant (LA) in TA patients. TA patients admitted to the Department of Rheumatology of Hacettepe University Faculty of Medicine between December 2015 and September 2016 who fulfilled the American College of Rheumatology (ACR) classification criteria for TA were consecutively enrolled in the study. Patients were grouped according …
Tularemia Seroprevalence In Humans In The Region Of The Hittite-Arzawa War (Inner Aegean Region), Where The First Biological Weapon Was Used 3300 Years Ago, İsmai̇l Davarci, Canan Eryildiz, Duygu Perçi̇n Renders, Ufuk Berberoğlu, Şaban Gürcan
Tularemia Seroprevalence In Humans In The Region Of The Hittite-Arzawa War (Inner Aegean Region), Where The First Biological Weapon Was Used 3300 Years Ago, İsmai̇l Davarci, Canan Eryildiz, Duygu Perçi̇n Renders, Ufuk Berberoğlu, Şaban Gürcan
Turkish Journal of Medical Sciences
Background/aim: According to Egyptian records, tularemia emerged in the Canaan region, where it was first identified and spread to Anatolia over the Euphrates. It was used as an active biological weapon for the first time in the Hittite-Arzawa War in 1320-1318 BC. This study aimed to investigate the seroprevalence of tularemia in the Inner Aegean Region, which is thought to be the region where this war was fought 3300 years ago. Materials and methods: Tularemia seropositivity in humans was investigated in 27 villages/neighborhoods in 3 districts in each of Manisa, Kütahya, and Uşak provinces. Before the study, the participants were …
Risk Factors For Icu Mortality In Patients With Hematological Malignancies: A Singlecenter, Retrospective Cohort Study From Turkey, Şahender Gülbi̇n Aygencel Bikmaz, Onur Gökçe, Meryem Merve Haşi̇moğlu, Nazlihan Boyaci, Melda Türkoğlu, Zeynep Arzu Yegi̇n, Zübeyde Nur Özkurt, Abdullah Münci̇ Yağci
Risk Factors For Icu Mortality In Patients With Hematological Malignancies: A Singlecenter, Retrospective Cohort Study From Turkey, Şahender Gülbi̇n Aygencel Bikmaz, Onur Gökçe, Meryem Merve Haşi̇moğlu, Nazlihan Boyaci, Melda Türkoğlu, Zeynep Arzu Yegi̇n, Zübeyde Nur Özkurt, Abdullah Münci̇ Yağci
Turkish Journal of Medical Sciences
Background/aim: Patients with hematological malignancies (HM) often require admission to the intensive care unit (ICU) due to organ failure, disease progression or treatment-related complications, and they generally have a poor prognosis. Therefore, understanding the factors affecting ICU mortality in HM patients is important. In this study, we aimed to identify the risk factors for ICU mortality in our critically ill HM patients. Materials and methods: We retrospectively reviewed the medical records of HM patients who were hospitalized in our medical ICU between January 1, 2010 and December 31, 2018. We recorded some parameters of these patients and compared these parameters …
Characteristics Of Children With Cat Sensitivity: A Prospective Cross-Sectional Study, Ezgi̇ Ulusoy Severcan, Nevzat Başkaya, Ayşegül Ertuğrul, Zeynep Şengül Emeksi̇z, İlknur Bostanci
Characteristics Of Children With Cat Sensitivity: A Prospective Cross-Sectional Study, Ezgi̇ Ulusoy Severcan, Nevzat Başkaya, Ayşegül Ertuğrul, Zeynep Şengül Emeksi̇z, İlknur Bostanci
Turkish Journal of Medical Sciences
Background/aim: Animal dander is one of the most common respiratory allergens in children, and there is evidence that cat sensitivity is a risk factor for asthma and allergic rhinitis. In this study, it was aimed to evaluate children with cat sensitivity and to identify their demographic and clinical characteristics. Materials and methods: Patients who were found to be sensitive to cats following skin prick tests performed in our allergy clinic over a period of one year (and two control groups), were included in the study. Patients in the study and control groups filled in a questionnaire including demographic and clinical …
The Molecular Regulators, Pathways, And Environmental Impacts Of White Flowers, Sagheer Ahmad, Zaibun Nisa, Muhammad Zeeshan Munir, Muhammad Imran, Shaista Nosheen, Kai Zhao
The Molecular Regulators, Pathways, And Environmental Impacts Of White Flowers, Sagheer Ahmad, Zaibun Nisa, Muhammad Zeeshan Munir, Muhammad Imran, Shaista Nosheen, Kai Zhao
Turkish Journal of Agriculture and Forestry
White flowers are an important element of natural beauty, although they are thought of colorless. Anthocyanins are the major compounds responsible for a variety of pigments in flowers. White flowers surely lack pigmented anthocyanins and other compounds, but there are regulatory mechanisms that hinder the deposition of color pigments in white flowers. Moreover, there are also some compounds that deposit to instigate white appearance and the genetic regulators control the biosynthesis and deposition of such compounds. Experts have shown that fluctuation in the equilibrium of FLS and DFR genes determines the degree of accumulation of anthocyanins and flavonols in the …
A Concise Study On Essential Parameters For The Sustainability Of Lagoon Waters In Terms Of Scientific Literature, Shuraik Kader, Morufu Olalekan Raimi, Velibor Spalevic, Austin-Asomeji Iyingiala, Raheem Waliyat Bukola, Lizny Jaufer, Talib E. Butt
A Concise Study On Essential Parameters For The Sustainability Of Lagoon Waters In Terms Of Scientific Literature, Shuraik Kader, Morufu Olalekan Raimi, Velibor Spalevic, Austin-Asomeji Iyingiala, Raheem Waliyat Bukola, Lizny Jaufer, Talib E. Butt
Turkish Journal of Agriculture and Forestry
Agriculture encompasses both plant growing (agronomy, horticulture, and forestry) and animal husbandry. Aquaculture is the aquatic embodiment of agriculture. Lagoons are the main sources of aquaculture in various countries around the world which especially yield shrimp, finfish, macrophytes, and mollusk. Agricultural effluents are highly affecting the lagoon water quality parameters in Sri Lanka since most of the agricultural farmlands in the country are on coastal landmasses. It leads to the increased risks of lagoon water contamination. Therefore, it is essential to identify the water quality parameters affected by anthropogenic agricultural activities and establish their threshold limits for ensuring the sustainability …
Genetic Diversity, Heritability, Correlation Coefficient, And Path Analysis Of Forage Yield Components In Iranian Phalaris Aquatica L. Genotypes, Reza Mohammadi, Alireza Pourmohammad, Mohammad Bagher Hassanpouraghdam, Serap Di̇ler
Genetic Diversity, Heritability, Correlation Coefficient, And Path Analysis Of Forage Yield Components In Iranian Phalaris Aquatica L. Genotypes, Reza Mohammadi, Alireza Pourmohammad, Mohammad Bagher Hassanpouraghdam, Serap Di̇ler
Turkish Journal of Agriculture and Forestry
Twenty-six selected genotypes of Phalaris aquatica L. from Iranian germplasm were evaluated to evaluate the genetic diversity of some agromorphological characteristics. Each selected genotype was cloned and planted as spaced single plants according to a randomized complete block design (RCBD) with four replications in 2016 and 2017. Large and significant (p < 0.01) differences among genotypes were found for all traits. The estimates of broad sense heritability were low to high (h$^{2}$$_{b}$ = 0.16 - 0.75) for studied traits. High heritability estimates for dry matter yield (DMY) indicate a sufficient genetic variability for further improvement. There was the highest heritability rate and genetic advance for plant height and DMY. Selection for traits with high heritability and genetic advance can be successful. The dry matter yield cut 1 (DMY1) correlation with the number of days to flowering, number of days to pollination, plant height, and crown diameter cut 2 was positive and significant. In stepwise multiple linear regression, the plant height, number of stems per plant, and spike length explained more than 84% of the total variation of DMY1. The plant height was the most crucial component of DMY1. The path analysis showed that plant height positively affected DMY1 (0.83). The highest negative indirect effects on DMY1 were observed for plant height via the number of stems per plant (-0.238). Axes 1 and 2 of the principal coordinate analysis explained 40.94% and 18.48% of the variation, respectively, and, although not entirely separated, general groupings can be determined. In factor analysis, component 1 was positively associated with the traits dry matter yield cut 2 (DMY2) (0.855), dry matter yield (0.821), and plant height (0.755). Therefore, the first component can be called the biomass component. Finally, selection would be more effective in improving forage yield based on yield components. In conclusion, the results indicated appropriate genetic variability in the studied genotypes. However, the studied genotypes will deliver a valuable germplasm to employ in breeding programs for forage cultivar production. This progress is crucial in introducing these selected genotypes to develop a core collection of Phalaris aquatica germplasm in Iran.
Effect Of Row Spacing Under Maize-Soybean Relay Intercropping System On Yield, Competition, And Economic Returns, Muhammad Hayder Bin Khalid, Liang Cui, Ghulam Abbas, Muhammad Ali Raza, Adeel Anwar, Zaheer Ahmed, Abdul Waheed, Amjad Saeed, Waqas Ahmed, Muhammad Jawad Babar, Shakeel Ahmad, Rezwan Tariq, Muhammad Maroof Ajmal, Ali Ahsan Bajwa, Hülya Doğan
Effect Of Row Spacing Under Maize-Soybean Relay Intercropping System On Yield, Competition, And Economic Returns, Muhammad Hayder Bin Khalid, Liang Cui, Ghulam Abbas, Muhammad Ali Raza, Adeel Anwar, Zaheer Ahmed, Abdul Waheed, Amjad Saeed, Waqas Ahmed, Muhammad Jawad Babar, Shakeel Ahmad, Rezwan Tariq, Muhammad Maroof Ajmal, Ali Ahsan Bajwa, Hülya Doğan
Turkish Journal of Agriculture and Forestry
Interrow spacing of intercrop species directly affects yield and competition indices such as land equivalent ratio of intercropping. The objectives of this research were to analyze (i) the maize and soybean yields under different spatial arrangements in maize-soybean relay strip intercropping (MSR) and (ii) the interspecies competition to provide a basis for optimization of rowspacing in MSR. The field trial was conducted in 2011 and 2012 at the Research Farm of the Sichuan Agricultural University in Ya'an to determine the impacts of various interrow planting distances on yield and competition indices in cereal (maize crop)-legume (soybean crop) relay strip intercropping. …
Rectal Temperature And Respiration Rate As Indicators Of Heat Stress In Broiler Chickens Subjected To Early-Age Thermal Conditioning And Vitamin C Supplementation, Zoran Ruzic, Zdenko Kanacki, Slobodan Stojanovic, Zorana Kovacevic, Slobodan Knezevic, Srdan Todorovic, Smiljana Paras
Rectal Temperature And Respiration Rate As Indicators Of Heat Stress In Broiler Chickens Subjected To Early-Age Thermal Conditioning And Vitamin C Supplementation, Zoran Ruzic, Zdenko Kanacki, Slobodan Stojanovic, Zorana Kovacevic, Slobodan Knezevic, Srdan Todorovic, Smiljana Paras
Turkish Journal of Veterinary & Animal Sciences
One of the major concerns in poultry production presents heat stress (HS) and it is followed by significant economic loss manifested by reduced growth, decreased immune response, increased mortality, etc. The objective of this study was to investigate whether the early-age thermal conditioning (ETC) and vitamin C (Vit.C) treatments, individually and in combination, produce their beneficial effects through increased heat release manifested as a change in respiration rate consequentially leading to a decrease in the chicken's body temperature and thus reduce the harmful effects of HS. A 400 broiler chicks mixed sex male and female were split into four groups. …
Design, Synthesis, And Enzyme Inhibition Evaluation Of Some Novel Mono- And Di-O-Ss-D-Glycopyranosyl Chalcone Analogues With Molecular Docking Studies, Gonca Çeli̇k, Gi̇zem Tatar Yilmaz, Hüseyi̇n Şahi̇n, Burak Barut, Nuretti̇n Yayli
Design, Synthesis, And Enzyme Inhibition Evaluation Of Some Novel Mono- And Di-O-Ss-D-Glycopyranosyl Chalcone Analogues With Molecular Docking Studies, Gonca Çeli̇k, Gi̇zem Tatar Yilmaz, Hüseyi̇n Şahi̇n, Burak Barut, Nuretti̇n Yayli
Turkish Journal of Chemistry
In this study, some novel mono- and di-O-β-D-glycopyranosyl chalcone analogs were designed, synthesized, and characterized. The chalcone derivatives were synthesized with good yields by base-catalyzed Claisen-Schmidt condensation in EtOH solution. Then these chalcones were reacted with TAGBr (2,3,4,6-tetra-O-acetyl-μ-D-glucopyranosylbromide) in dry acetone under the anhydrous condition at 0-5 °C. Deacylated was carried out by the Zemplen's method with NaOCH3 in dry methanol results in substituted chalcone-O-glycosides (mono- and di-O-β-D-glycopyranosyl chalcone analogs). The chemical structures of all synthesized compounds were elucidated based on IR, NMR spectral data, and mass spectrometry. Further, the compounds (7a-c, 8a-c, 12a-c, 16a-c, and 17a-c) …