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Partially Purified Glycine Max Proteinase Inhibitors: Potential Bioactive Compounds Against Tobacco Cutworm, Spodoptera Litura (Fabricius, 1775) (Lepidoptera: Noctuidae), Arti Vasudev, Satwinder Sohal
Partially Purified Glycine Max Proteinase Inhibitors: Potential Bioactive Compounds Against Tobacco Cutworm, Spodoptera Litura (Fabricius, 1775) (Lepidoptera: Noctuidae), Arti Vasudev, Satwinder Sohal
Turkish Journal of Zoology
Spodoptera litura (Fabricius, 1775), a polyphagous defoliator with broad host spectrum, causes significant damage to agriculturally important crops. Serine protease is primarily responsible for most of the proteolytic activity in the larval gut of lepidopteran insects. Second-instar larvae were reared on an artificial diet containing serine trypsin inhibitor partially purified from Glycine max seeds. Different concentrations were amended in the diet, i.e. 25, 50, 100, 200, and 400 μg/mL. The larval development period, total developmental period, longevity, fecundity, larval weight, and mean relative growth rate were decreased at the 100 μg/mL concentration. However, with further increase in concentration, the above …
A Comparative Study Of The Aquatic Insect Diversity Of Two Ponds Located In Cachar District, Assam, India, Arpita Dalal, Susmita Gupta
A Comparative Study Of The Aquatic Insect Diversity Of Two Ponds Located In Cachar District, Assam, India, Arpita Dalal, Susmita Gupta
Turkish Journal of Zoology
Ponds play a vital role in the conservation of aquatic biodiversity at the local level apart from other lakes and rivers. A comparative study was carried out on the aquatic insect diversity of two different ponds, one in an urban area (urban pond, UP) and another in a rural area (Jalinga pond, JP). Two seasonal collections (postmonsoon and winter) were made to check the pollution status of the two ponds based on the aquatic insect community and physicochemical properties of water. Consequently, 29 species, 17 families, and 5 orders of aquatic insects from UP and 17 species, 8 families, and …
Three New Species Of The Genus Macroocula Panfilov, 1954 (Hymenoptera: Bradynobaenidae: Apterogyninae) From Saudi Arabia, Ahmed Soliman, Neveen Gadallah, Hathal Aldhafer
Three New Species Of The Genus Macroocula Panfilov, 1954 (Hymenoptera: Bradynobaenidae: Apterogyninae) From Saudi Arabia, Ahmed Soliman, Neveen Gadallah, Hathal Aldhafer
Turkish Journal of Zoology
Three new species of the genus Macroocula Panfilov, 1954 from Saudi Arabia are described and illustrated: M. Atuberculata Soliman and Gadallah sp. Nov. (Al-Quwayiyah, Al-Aflag, Al-Zulfi, and Riyadh), M. Zulfiensis Soliman and Gadallah sp. Nov. (Al-Zulfi and Riyadh), and M. Khorimensis Soliman and Gadallah sp. Nov. (Muzahimiyah and Riyadh). A key to Macroocula species with a ventral protuberance on the hind trochanter is provided.
The Community Members Associated With Rose Gall Wasp Diplolepis Fructuum (Rübsaamen, 1895) (Hymenoptera: Cynipidae) In Tokat Province Of Turkey, Özlem Mete, Yusuf Orhan Mergen
The Community Members Associated With Rose Gall Wasp Diplolepis Fructuum (Rübsaamen, 1895) (Hymenoptera: Cynipidae) In Tokat Province Of Turkey, Özlem Mete, Yusuf Orhan Mergen
Turkish Journal of Zoology
Field studies were carried out in April, October, and November 2013 and March and October 2014 in Tokat Province of Turkey. Gall specimens of Diplolepis fructuum (Rübsaamen, 1895) (Hymenoptera: Cynipidae) on host plants from the genus Rosa were collected. Thirteen species from six families were reared. Among them, Eurytoma caninae Lotfalizadeh and Delvare, 2007 and Aximopsis collina (Zerova, 1984) are new records for Turkey. The most common parasitoids are Eupelmus urozonus Dalman, 1820 and Stepanovia eurytomae (Nees, 1834), respectively.
On The Presence Of Lumbricus Terrestris Linnaeus 1758 (Oligochaeta, Lumbricidae) On The Balkan Peninsula: Some Aspects Of Ecology And Distribution, İbrahi̇m Mete Misirlioğlu, Ralitsa Tsekova, Mirjana Stojanovic
On The Presence Of Lumbricus Terrestris Linnaeus 1758 (Oligochaeta, Lumbricidae) On The Balkan Peninsula: Some Aspects Of Ecology And Distribution, İbrahi̇m Mete Misirlioğlu, Ralitsa Tsekova, Mirjana Stojanovic
Turkish Journal of Zoology
In this paper we summarize the current knowledge on the distribution of Lumbricus terrestris on the Balkan Peninsula. For this purpose we reviewed all published data on its distribution in addition to original data from our old institute collection and recent field investigations. The objective of this paper is to analyze the whole list of records in order to present a general overview of the distribution of Lumbricus terrestris on the Balkan Peninsula. Based on literature data, we also give some possible explanations of ecological influences on the current range characteristics. It belongs to peregrine species native to the Palearctic …
Microhabitats And Fragmentation Effects On A Ground Beetle Community (Coleoptera: Carabidae) In A Mountainous Beech Forest Landscape, Slav?O Hristovski, Aleksandra Cvetkovska-Gjorgievska, Trajce Mitev
Microhabitats And Fragmentation Effects On A Ground Beetle Community (Coleoptera: Carabidae) In A Mountainous Beech Forest Landscape, Slav?O Hristovski, Aleksandra Cvetkovska-Gjorgievska, Trajce Mitev
Turkish Journal of Zoology
The aim of this investigation was to analyze the effects of microhabitats and forest fragmentation on the composition and species abundance of a ground beetle community from three different beech forest patches on Mt. Osogovo (Macedonia), as well as to analyze the mobility (based on mark-recapture of individuals) and seasonal dynamics and sex ratio of the ground beetle community. The study site included three localities (A, B, C), one of them fragmented (A), with four microhabitats (open area, ecotone, forest stand, and forested corridor). Ground beetles were collected using pitfall traps during four sampling months (June-September 2009) that were operational …
Effects Of Agroecosystems On Insect And Insectivorous Bat Activity: A Preliminary Finding Based On Light Trap And Mist Net Captures, Eric Adjei Lawer, Esther Love Darkoh
Effects Of Agroecosystems On Insect And Insectivorous Bat Activity: A Preliminary Finding Based On Light Trap And Mist Net Captures, Eric Adjei Lawer, Esther Love Darkoh
Turkish Journal of Zoology
This study investigated the effects of agroecosystems on predator-prey activities. Therefore, bats and insects were sampled from various agroecosystems using mist netting and light trapping techniques. A generalized linear model was then employed to analyze some biotic and abiotic factors' effects on insect and insectivorous bat activities. The results indicate that agroecosystems and lunar cycles have significant effects on insect activity (Lepidopteran, Dipteran, and total insect activity) and insectivorous bat activity (Hipposideros jonesi, Hipposideros aff. Ruber, and overall insectivorous bat activity). Generally, inorganic farms recorded the least insect and insectivorous bat activity, while fallow lands and teak plantations obtained higher …
Role Of Indian Flying Fox Pteropus Giganteus Brünnich, 1782 (Chiroptera: Pteropodidae) As A Seed Disperser In Urban Areas Of Lahore, Pakistan, Tayiba Gulraiz, Arshad Javid, Muhammad Mahmood-Ul-Hassan, Syed Hussain, Hamda Azmat, Sharoon Daud
Role Of Indian Flying Fox Pteropus Giganteus Brünnich, 1782 (Chiroptera: Pteropodidae) As A Seed Disperser In Urban Areas Of Lahore, Pakistan, Tayiba Gulraiz, Arshad Javid, Muhammad Mahmood-Ul-Hassan, Syed Hussain, Hamda Azmat, Sharoon Daud
Turkish Journal of Zoology
This 1-year study, extending from January to December 2011, was conducted to investigate the role of the Indian flying fox (Pteropus giganteus) as a seed disperser in Lahore, Pakistan. Ejecta of the species from two roosting sites, i.e. Jinnah garden and Lalazar garden, was collected and the plant seeds were extracted from bat boluses and guano. Various seeds of edible trees and forest plantation species extracted from ejecta of P. Giganteus included areca palm (Areca catechu), coromandel ebony (Diospyros melanoxylon), Indian gaabh (D. Peregrina), lemon-scented gum (Eucalyptus citriodora), Chinese fan palm (Livistona chinensis), sapodilla (Manilkara zapota), mahwa (Madhuca longifolia), Indian …
Interesting Rotifers (Rotifera: Eurotatoria) From A Subtropical Wetland Of Meghalaya, Northeast India: New Records, Bhushan Kumar Sharma
Interesting Rotifers (Rotifera: Eurotatoria) From A Subtropical Wetland Of Meghalaya, Northeast India: New Records, Bhushan Kumar Sharma
Turkish Journal of Zoology
The plankton and semiplankton samples examined from a subtropical wetland of Shillong, Meghalaya, Northeast India (NEI), revealed seven new records of rotifers belonging to six genera and six families. These include five species new to the Indian Rotifera and two species new to the rotifer fauna of NEI, thus meriting interest in terms of biodiversity and distribution. All the species are illustrated to warrant validation. While a detailed account of the rich rotifer diversity of the wetland is continuing, this interim report raises the total tally of Rotifera known from Meghalaya to 141 species belonging to 41 genera and 20 …
Faunistic Survey On The Agathidinae (Hymenoptera: Braconidae) In The Central Anatolia Region With A New Record For The Turkish Fauna: Bassus Tegularis (Thomson, 1895), Özlem Çeti̇n Erdoğan, Ahmet Beyarslan
Faunistic Survey On The Agathidinae (Hymenoptera: Braconidae) In The Central Anatolia Region With A New Record For The Turkish Fauna: Bassus Tegularis (Thomson, 1895), Özlem Çeti̇n Erdoğan, Ahmet Beyarslan
Turkish Journal of Zoology
This study is based upon material of the subfamily Agathidinae collected from different localities in the Central Anatolia Region of Turkey from 1988 to 2008. The study resulted in the recording for the Turkish fauna of 14 species belonging to 3 genera (Agathis Latreille, 1804; Bassus Fabricius, 1804; and Disophrys Förster, 1862) within the subfamily Agathidinae. Agathis fischeri Zettel and Beyarslan, Agathis fulmeki Fischer, Agathis fuscipennis (Zetterstedt), Agathis glaucoptera Nees, Agathis lugubris (Förster), Agathis malvacearum Latreille, Agathis nigra Nees, Agathis varipes Thomson, Bassus linguarius (Nees), Bassus tumidulus (Nees), and Disophrys caesa (Klug) are recorded for the first time in the …
New Records Of Cuvier's Beaked Whales (Ziphius Cavirostris) From The Turkish Levantine Sea, Ayli̇n Akkaya Baş, João Lagoa, Elizabeth Atchoi
New Records Of Cuvier's Beaked Whales (Ziphius Cavirostris) From The Turkish Levantine Sea, Ayli̇n Akkaya Baş, João Lagoa, Elizabeth Atchoi
Turkish Journal of Zoology
Cuvier's beaked whales were sighted once on each of three different surveys over Antalya Canyon, in June and September 2015. Sightings took place in waters between 600 and 1000 m in depth and at 8 km from the closest shore. While the first sighting was positively identified as Cuvier's beaked whale (Ziphius cavirostris (G. Cuvier, 1823)), latter sightings could not be identified to the species level. Nevertheless, noting that latter sightings had a similar spatial and temporal distribution to the first one and that there is an overwhelming difference between the probabilities of sighting Cuvier's beaked whales versus Mesoplodon sp. …
First Record Of The Genus Dactylothrombium Feider, 1952 (Acari: Microtrombidiidae) From Turkey, Sezai̇ Adi̇l, Sevgi̇ Sevsay, Sali̇h Doğan, Si̇bel Di̇lkaraoğlu
First Record Of The Genus Dactylothrombium Feider, 1952 (Acari: Microtrombidiidae) From Turkey, Sezai̇ Adi̇l, Sevgi̇ Sevsay, Sali̇h Doğan, Si̇bel Di̇lkaraoğlu
Turkish Journal of Zoology
In this study, diagnoses and original drawings of Dactylothrombium pulcherrimum (Haller, 1882) are given for postlarval forms. Morphometric data for adults and deutonymphs are given. Information about habitat and distribution for the species is also provided. The genus Dactylothrombium is recorded for the first time from Turkey.
Effects Of Amniotic Fluid Mesenchymal Stem Cells In Carboxymethyl Cellulosegel On Healing Of Spontaneous Pressure Sores: Clinical Outcome In Sevenhospitalized Neonatal Foals, Eleonora Iacono, Aliai Lanci, Barbara Merlo, Francesca Ricci, Alessandro Pirrone, Carlotta Antonelli, Jole Mariella, Carolina Castagnetti
Effects Of Amniotic Fluid Mesenchymal Stem Cells In Carboxymethyl Cellulosegel On Healing Of Spontaneous Pressure Sores: Clinical Outcome In Sevenhospitalized Neonatal Foals, Eleonora Iacono, Aliai Lanci, Barbara Merlo, Francesca Ricci, Alessandro Pirrone, Carlotta Antonelli, Jole Mariella, Carolina Castagnetti
Turkish Journal of Biology
In the present study, an innovative therapy for spontaneously arisen pressure sores in seven hospitalized neonatal foals is described, using mesenchymal stem cells obtained from equine amniotic fluid. Amniotic fluid mesenchymal stem cells (AFMSCs) were isolated from fluid samples recovered at delivery. Heterologous cells, at passage three of in vitro culture, were applied to sores twice a week for four consecutive times in a carboxymethylcellulose (CMC) gel. As a control, a commercial ointment was used. The results showed that the mean sore regression rate with AFMSCs in CMC gel was statistically higher than the mean value recorded in the control …
First Record Of The Genus Lucoppia (Acari: Oribatida) From Turkey, Tunahan Bezci̇, Şule Baran
First Record Of The Genus Lucoppia (Acari: Oribatida) From Turkey, Tunahan Bezci̇, Şule Baran
Turkish Journal of Zoology
Redescription and SEM images of Lucoppia burrowsi (Michael, 1890) are given. The genus Lucoppia is recorded for the first time in Turkey.
Apoptotic Induction Via Membrane/Dna Damage And Metabolic Inactivation By Synthetic Food Colorants In Allium Cepa Root Meristem, Prajitha Vazhangat, John Ernest Thoppil
Apoptotic Induction Via Membrane/Dna Damage And Metabolic Inactivation By Synthetic Food Colorants In Allium Cepa Root Meristem, Prajitha Vazhangat, John Ernest Thoppil
Turkish Journal of Biology
The present study investigates the cytotoxic and genotoxic effects of two frequently employed synthetic food colorants, lemon yellow and orange red, using an Allium cepa assay. Uptake of food colorants by root cells at different concentrations and varied exposures significantly altered the cytogenetic system, membrane integrity, mitochondrial function, root growth, and cell division. The food colorants induced significant DNA damage, micronucleus formation, and other severe chromosomal aberrations at genetic level and inhibited cell division as well as root growth. Severe DNA damage, membrane damage, and metabolic inactivation observed in the result are indicative of apoptotic cell death. These results confirm …
Sensitization To Food And Inhalant Allergens In Healthy Children In Van, East Turkey, Mehmet Parlak, Ayteki̇n Çikman, Yasemi̇n Bayram, Nesri̇n Ceylan, Ulaş Çalişir, Mustafa Berktaş
Sensitization To Food And Inhalant Allergens In Healthy Children In Van, East Turkey, Mehmet Parlak, Ayteki̇n Çikman, Yasemi̇n Bayram, Nesri̇n Ceylan, Ulaş Çalişir, Mustafa Berktaş
Turkish Journal of Medical Sciences
Background/aim: The purpose of this study was to determine the most frequent food and inhalant allergens leading to allergic sensitization in children in Van Province of Turkey. Materials and methods: The study included 1052 serum samples with no diagnosis of allergy. The sera were tested with the Euroline Pediatric IgE test kit (EUROIMMUN, Germany). By using the EUROLineScan digital evaluation system, the intensity of bands was calculated with enzyme allergosorbent test classification. Results: Out of the 1052 tested sera, 143 were found to be cross-reactive carbohydrate determinant-positive and were discarded from the study. Of the remaining 909 sera, 513 (56%) …
The Prevalence Of Tularemia In Occupational Groups That Have Contact With Animals, Fati̇h Büyük, Özgür Çelebi̇, Eli̇f Çeli̇k, Beki̇r Çelebi̇, Selçuk Kiliç, Ali̇ye Gülmez Sağlam, Doğan Akça, Mehmet Doğanay, Sali̇h Otlu, Mi̇tat Şahi̇n
The Prevalence Of Tularemia In Occupational Groups That Have Contact With Animals, Fati̇h Büyük, Özgür Çelebi̇, Eli̇f Çeli̇k, Beki̇r Çelebi̇, Selçuk Kiliç, Ali̇ye Gülmez Sağlam, Doğan Akça, Mehmet Doğanay, Sali̇h Otlu, Mi̇tat Şahi̇n
Turkish Journal of Medical Sciences
Background/aim: The aim of the current study was to investigate the presence of antibodies against Francisella tularensis in individuals in different occupations that have contact with animals in the Kars region of northeastern Turkey. Materials and methods: A total of 201 blood samples specifically including 103 farmers, 45 clinical veterinarians, 42 butchers, and 11 hunters were analyzed. The results of the study were reported in relation to some sociodemographic features (age, sex, occupation, and experience) of the volunteers. The presence of antibodies was determined by a microagglutination (MA) test. In addition, positive sera were confirmed using an ELISA kit. Results: …
Traditional Practices Of Konya Women During Pregnancy, Birth, The Postpartumperiod, And Newborn Care, Berri̇n Okka, Yasemi̇n Durduran, Nesli̇han Değerli̇ Kodaz
Traditional Practices Of Konya Women During Pregnancy, Birth, The Postpartumperiod, And Newborn Care, Berri̇n Okka, Yasemi̇n Durduran, Nesli̇han Değerli̇ Kodaz
Turkish Journal of Medical Sciences
Background/aim: The purpose of the present study was to identify traditional practices and the extent to which they are practiced by mothers during pregnancy, birth, the postpartum period, and newborn care. Materials and methods: This study was conducted in the city center of Konya (Turkey). Data were collected through questionnaires completed by volunteers. The research sample comprised 450 mothers, all of whom had given birth to at least one live baby. The forms were completed during face-to-face interviews. Results: Some traditional pregnancy practices were followed by 70.7% of the participants. Of the women who performed these practices, 57.4% consciously chose …
Free Radical-Induced Nephrotoxicity Following Repeated Oral Exposureto Chlorpyrifos Alone And In Conjunction With Fluoride In Rats, Naseer Baba, Rajinder Raina, Pawan Verma, Mudasir Sultana
Free Radical-Induced Nephrotoxicity Following Repeated Oral Exposureto Chlorpyrifos Alone And In Conjunction With Fluoride In Rats, Naseer Baba, Rajinder Raina, Pawan Verma, Mudasir Sultana
Turkish Journal of Medical Sciences
Background/aim: Chronic renal disorder is becoming a major health problem worldwide. The purpose of the present study was to investigate alterations in the renal antioxidant system in rats induced by repeated exposure to chlorpyrifos (CPF) alone and in conjunction with fluoride. Materials and methods: Wistar rats were randomly allocated to seven groups, each consisting of six rats, and were subjected to different treatment regiments for 28 days. Results: Significant increases (P < 0.05) in plasma protein, blood urea nitrogen, and creatinine levels indicated alterations in renal functions on repeated exposure to CPF or fluoride; moreover, these changes were more pronounced in animals exposed to both toxicants concurrently. A significant increase (P < 0.05) in malondialdehyde levels and decreases in superoxide dismutase, catalase, and glutathione peroxidase activities in renal tissue were noted, indicating renal damage on exposure to CPF, fluoride, or the combination of those. Conclusion: Our observations suggested that the concurrent exposure to CPF and fluoride increased the extent of renal damage. These findings indicate that this damage is due to increased free radical formation and a reduced function of the antioxidant system in renal tissue. Thus, the application of CPF as an insecticide should be reduced in areas where the fluoride levels in ground waters are high in order to minimize renal damage in exposed populations.
Combination Immunotherapy With Extract Of Heated 4t1 And Naloxone In Mouse Model Of Breast Cancer, Shervin Jahangiri, Seyyed Meysam Abtahi Froushani, Norouz Delirezh
Combination Immunotherapy With Extract Of Heated 4t1 And Naloxone In Mouse Model Of Breast Cancer, Shervin Jahangiri, Seyyed Meysam Abtahi Froushani, Norouz Delirezh
Turkish Journal of Medical Sciences
Background/aim: This study was designed to investigate the efficacy of a new vaccine against breast cancer, which was made by mixing the extract of heated 4T1 cells and naloxone, as an adjuvant. Materials and methods: Female BALB/c mice of 6-8 weeks old were challenged subcutaneously in the right flanks with 4T1 cells. When all animals developed a palpable tumor, immunotherapy was initiated. Mice in the experimental groups received, twice with a 1-week interval, either the extract of heated 4T1 alone or in combination with naloxone, and mice in the negative control group received phosphate-buffered saline. One week after the last …
Comparison Between The Protective Effects Of Vitamin K And Vitamin A On The Modulation Of Hypervitaminosis D3 Short-Term Toxicity In Adult Albino Rats, Said Said Elshama, Hosam-Eldin Hussein Osman, Ayman El-Meghawry El-Kenawy, Hamdi Mohamed Youseef
Comparison Between The Protective Effects Of Vitamin K And Vitamin A On The Modulation Of Hypervitaminosis D3 Short-Term Toxicity In Adult Albino Rats, Said Said Elshama, Hosam-Eldin Hussein Osman, Ayman El-Meghawry El-Kenawy, Hamdi Mohamed Youseef
Turkish Journal of Medical Sciences
Background/aim: Vitamin D3 has increased risk of toxicity due to its common use in multivitamin preparations. Vitamin K and vitamin A play an important role in vitamin D action. The goal of the current study was to compare the protective effects of vitamin K and vitamin A on the modulation of hypervitaminosis D3 toxicity in rats by assessing serum calcium, renal function tests, cardiac enzymes, and related histopathological changes. Materials and methods: Eighty adult albino rats were divided into four groups; each group consisted of 20 rats. The first group received water; the second received a toxic dose of vitamin …
Evaluation Of The Effectiveness Of Biodegradable Electrospun Caprolactoneand Poly(Lactic Acid-?-Caprolactone) Nerve Conduits For Peripheral Nerveregenerations In A Rat Sciatic Nerve Defect Model, Mehmet Dadaci, Ni̇met Karagülle, Erhan Sönmez, Zeynep Dadaci, Evren Tevfi̇k İşci̇, Bi̇lsev İnce, İbrahi̇m Vargel, Erhan Pi̇şki̇n, Ali̇ Yücel Erk
Evaluation Of The Effectiveness Of Biodegradable Electrospun Caprolactoneand Poly(Lactic Acid-?-Caprolactone) Nerve Conduits For Peripheral Nerveregenerations In A Rat Sciatic Nerve Defect Model, Mehmet Dadaci, Ni̇met Karagülle, Erhan Sönmez, Zeynep Dadaci, Evren Tevfi̇k İşci̇, Bi̇lsev İnce, İbrahi̇m Vargel, Erhan Pi̇şki̇n, Ali̇ Yücel Erk
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to compare electrospun caprolactone (EC) and poly(lactic acid-?-caprolactone) (PLCL) nerve conduits with nerve graft in a rat sciatic nerve defect model. Materials and methods: A total of 32 male Wistar albino rats were divided into 4 groups, with 8 rats in each group. A nerve defect of 1 cm was constructed in the left sciatic nerve of the rats. These defects were left denuded in the sham group, and reconstructed with nerve grafts, PLCL, and EC nerve conduits in the other groups. After 3 months, nerve regenerations were evaluated macroscopically, microscopically, and electrophysiologically. …
Ameliorating Effects Of Curcumin On Nicotine-Induced Mice Testes, Gülfi̇dan Coşkun, Hülya Özgür, Şaban Doran, Sai̇t Polat
Ameliorating Effects Of Curcumin On Nicotine-Induced Mice Testes, Gülfi̇dan Coşkun, Hülya Özgür, Şaban Doran, Sai̇t Polat
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to determine the antioxidative effect of curcumin on nicotine-induced mice testis. Materials and methods: Sixty Swiss albino male mice were divided into five groups, each containing 12 mice. The first group was used as a control. To induce toxicity in the second and third group, nicotine (0.4 mg/kg/day) was injected intraperitoneally into mice for 14 and 28 days, respectively. The mice in the fourth and fifth group were injected with nicotine (0.4 mg/kg/day) and orally treated with curcumin (200 mg/kg) for 14 and 28 days, respectively. Testosterone levels were measured from blood samples …
The Protective Effect Of Capparis Ovata In Acute Hepatotoxicity Induced By Paracetamol, Nurcan Doğan, Mustafa Akçam, Tuğba Koca, Duygu Kumbul Doğuç, Meltem Özgöçmen
The Protective Effect Of Capparis Ovata In Acute Hepatotoxicity Induced By Paracetamol, Nurcan Doğan, Mustafa Akçam, Tuğba Koca, Duygu Kumbul Doğuç, Meltem Özgöçmen
Turkish Journal of Medical Sciences
Background/aim: To investigate the efficiency of Capparis ovata as a protective agent against acute paracetamol toxicity of the liver. Materials and methods: A total of 36 Wistar albino rats were divided into 4 groups: 1) paracetamol, 2) Capparis ovata + paracetamol, 3) Capparis ovata, and 4) control. Groups 2 and 3 were given Capparis ovata and Groups 1 and 4 distilled water for 8 days. On day 8, 3000 mg kg-1 paracetamol was administered orally to Groups 1 and 2. Samples were taken on day 9. AST, ALT, total bilirubin, direct bilirubin, GGT, and ALP levels were assessed. Lipid peroxidation …
Role Of Flt3 In The Proliferation And Aggressiveness Of Hepatocellular Carcinoma, Muammer Merve Aydin, Nermi̇n Sumru Bayin, Tolga Acun, Mustafa Cengi̇z Yakicier, Kami̇l Can Akçali
Role Of Flt3 In The Proliferation And Aggressiveness Of Hepatocellular Carcinoma, Muammer Merve Aydin, Nermi̇n Sumru Bayin, Tolga Acun, Mustafa Cengi̇z Yakicier, Kami̇l Can Akçali
Turkish Journal of Medical Sciences
Background/aim: Previously we showed that Fms-like tyrosine kinase (FLT3) changes its cellular localization upon partial hepatectomy, suggesting a role in liver regeneration. FLT3 was also shown to play an important function in cellular proliferation and activation of PI3K and Ras. Thus, we aimed to investigate the role of FLT3 in hepatocellular tumorigenesis utilizing in vitro and in vivo models. Materials and methods: We used Snu398 cells that express FLT3. We investigated these cells' in vitro proliferation and invasion abilities by treatment with the FLT3 inhibitor K-252a or by knocking-down with FLT3 shRNA,. Furthermore, the effect of blocking FLT3 activity and …
Evaluation Of Tetanus Antibody Levels In Adults In Yozgat, Turkey, Çi̇ğdem Kader, Mehmet Balci, Ayşe Erbay
Evaluation Of Tetanus Antibody Levels In Adults In Yozgat, Turkey, Çi̇ğdem Kader, Mehmet Balci, Ayşe Erbay
Turkish Journal of Medical Sciences
Background/aim: To assess the immune status against tetanus in relation to self-declared vaccination status among an adult population in Yozgat, Turkey. Methods: Questionnaires and blood specimens were collected from 267 individuals over 18 years of age in Yozgat, Turkey. Antitetanus antibodies were determined quantitatively by enzyme-linked immunosorbent assay. Results: Among the 267 subjects (mean age 43.4 ± 15.6; male:female, 133:134) 168 (62.9%) had protective level of tetanus antibody titers. There was a characteristic distribution of the tetanus antibody titers in different age groups as it dropped with increasing age. Protective immunity was obtained in 74.1% of urban and 47.9% of …
Investigation Of Enteropathogenic Escherichia Coli And Shiga Toxin-Producing Escherichia Coli Associated With Hemolytic Uremic Syndrome In İzmir Province, Turkey, Eli̇f Bozçal, Gürkan Yi̇ği̇ttürk, Ataç Uzel, Sabi̇re Şöhret Aydemi̇r
Investigation Of Enteropathogenic Escherichia Coli And Shiga Toxin-Producing Escherichia Coli Associated With Hemolytic Uremic Syndrome In İzmir Province, Turkey, Eli̇f Bozçal, Gürkan Yi̇ği̇ttürk, Ataç Uzel, Sabi̇re Şöhret Aydemi̇r
Turkish Journal of Medical Sciences
Background/aim: The purpose of this study was to investigate Shiga toxin-producing Escherichia coli (STEC) and enteropathogenic Escherichia coli (EPEC) strains originating from diarrheagenic patients. Materials and methods: A total of 102 patients with diarrhea between October 2012 and January 2013 were enrolled in this study. Multiplex and standard polymerase chain reactions were performed to detect and distinguish STEC and EPEC strains. O serotyping of EPEC was carried out by monovalent antisera. The O and H serotyping of STEC strains was performed at the Refik Saydam Institute, Ankara. Results: A total of 5 (3.42%) strains were identified as STEC, and 3 …
Levels Of Nitric Oxide, Asymmetric Dimethyl Arginine, Symmetric Dimethyl Arginine,And L-Arginine In Patients With Obsessive-Compulsive Disorder, Enver Demi̇rel Yilmaz, Mehmet Fati̇h Üstündağ, Ali̇ Görkem Gençer, Yüksel Kivrak, Özge Ünal, Mustafa Bi̇li̇ci̇
Levels Of Nitric Oxide, Asymmetric Dimethyl Arginine, Symmetric Dimethyl Arginine,And L-Arginine In Patients With Obsessive-Compulsive Disorder, Enver Demi̇rel Yilmaz, Mehmet Fati̇h Üstündağ, Ali̇ Görkem Gençer, Yüksel Kivrak, Özge Ünal, Mustafa Bi̇li̇ci̇
Turkish Journal of Medical Sciences
Background/aim: We aimed to investigate and compare to healthy controls the variations in the levels of nitric oxide (NO), asymmetric dimethyl arginine (ADMA), symmetric dimethyl arginine (SDMA), and L-arginine levels in patients with obsessive-compulsive disorder (OCD). Materials and methods: We enrolled 30 patients with OCD and 30 healthy controls in the study consecutively. Diagnostic interviews of all participants were conducted with the Structured Clinical Interview for Axis I Disorders (SCID-I), and sociodemographic data of the participants were recorded. Patients scoring 10 points or more on the Yale-Brown Obsessive-Compulsive Scale were enrolled in the study. Results: The NO levels of patients …
Prospects Of Curcumin As An Additive In Storage Solutions: A Study On Erythrocytes, Soumya Ravikumar, Carl Hsieh, Vani Rajashekharaiah
Prospects Of Curcumin As An Additive In Storage Solutions: A Study On Erythrocytes, Soumya Ravikumar, Carl Hsieh, Vani Rajashekharaiah
Turkish Journal of Medical Sciences
Background/aim: Curcumin, a naturally occurring antioxidant, shows a wide variety of medicinal properties. The possibility of utilizing curcumin as an additive in storage solutions of blood has not been explored. The purpose of this study was to analyze the effect of curcumin on erythrocytes during storage. Materials and methods: Blood obtained from rats was stored (4 °C) for 20 days in citrate-phosphate-dextrose-adenine-1 solution. Samples were divided into four groups: 1) Controls; 2) Curcumin 10 mM; 3) Curcumin 30 mM; and 4) Curcumin 60 mM. Every fifth day, hemoglobin, superoxide, antioxidant enzymes (superoxide dismutase, catalase, and glutathione peroxidase (GSH-Px)), lipid peroxidation …
Hepatoprotective And Antidiabetic Activities Of Fraxinus Angustifolia Vahl Extracts In Animal Models: Characterization By High Performance Liquid Chromatography Analysis, Zineb Medjahed, Dina Atman-Kilani, Marie-Laure Fauconnier, Gaetan Richard, Djebbar Atmani
Hepatoprotective And Antidiabetic Activities Of Fraxinus Angustifolia Vahl Extracts In Animal Models: Characterization By High Performance Liquid Chromatography Analysis, Zineb Medjahed, Dina Atman-Kilani, Marie-Laure Fauconnier, Gaetan Richard, Djebbar Atmani
Turkish Journal of Medical Sciences
Background/aim: The present study was designed to explore antidiabetic and hepatoprotective potentials of Fraxinus angustifolia leaf (FAL) and bark (FAB) extracts in vivo. Materials and methods: Streptozotocin (STZ)-induced diabetic rats, pretreated with the extracts (25 and 50 mg/kg), were monitored for fasting blood glucose (FBG) levels. Hepatoprotective potential was examined after injection of an excessive dose of paracetamol (10 g/60 kg) by analysis of biochemical parameters (transaminases, bilirubin), malondialdehyde (MDA) levels, and histological sections. high performance liquid chromatography analysis was also performed for partial characterization. Results: A considerable hypoglycemic effect was noticed 2 h after the STZ-induction, with a higher …