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Losartan Inhibits Egfr Transactivation In Vascular Smooth Muscle Cells, Mustafa Kirça, Akin Yeşi̇lkaya
Losartan Inhibits Egfr Transactivation In Vascular Smooth Muscle Cells, Mustafa Kirça, Akin Yeşi̇lkaya
Turkish Journal of Medical Sciences
Background/aim: Angiotensin II (Ang II)-induced molecular signaling pathways play a significant role in the progression of cardiovascular diseases, including hypertension and atherosclerosis. In addition to the well-known effects of Ang II, it may activate epidermal growth factor receptor (EGFR) in a process known as transactivation, which contributes to vascular pathologies. The aim of this study was to determine whether losartan could reduce EGFR transactivation induced by Ang II. Additionally, we evaluated the roles of heparin-binding epidermal-like growth factor (HB-EGF) and matrix metalloproteinases (MMPs) in Ang II-induced EGFR transactivation. Materials and methods: Vascular smooth muscle cells were isolated from a rat …
Demonstration Of The Effect Of Brivaracetam On An Experimental Epilepsy Model, Mustafa Çeti̇ner, Hasan Emre Aydin
Demonstration Of The Effect Of Brivaracetam On An Experimental Epilepsy Model, Mustafa Çeti̇ner, Hasan Emre Aydin
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to investigate the effects of valproic acid (VPA) and a new-generation antiepileptic drug called brivaracetam (BRV) on the brain damage occurring after status epilepticus (SE) in rats. Materials and methods: In our study, an experimental animal model of SE, generated by stereotaxically injecting 0.4-2 μg of kainic acid into the rat hippocampus, was used. The laboratory animals were divided into 4 groups: the first group was a sham group that was subjected to anesthesia and SE was not induced; the second group was a SE group, in which SE was induced using kainic …
Investigation Of The Effect Of Combined Use Of Alloplastic-Based Tricalcium Phosphate Bone Graft And Antihemorrhagic Plant Extract (Abs) On Bone Regeneration In Surgically Induced Bone Defects In Nondiabetic Rats: An Experimental Animal Study, Abdulsamet Tani̇k, Arzum Güler Doğru, Veysi̇ Akpolat, Fi̇li̇z Acun Kaya, Ebru Saribaş, Mehmet Gül, Sevgi̇ İrtegün, Engi̇n Deveci̇
Investigation Of The Effect Of Combined Use Of Alloplastic-Based Tricalcium Phosphate Bone Graft And Antihemorrhagic Plant Extract (Abs) On Bone Regeneration In Surgically Induced Bone Defects In Nondiabetic Rats: An Experimental Animal Study, Abdulsamet Tani̇k, Arzum Güler Doğru, Veysi̇ Akpolat, Fi̇li̇z Acun Kaya, Ebru Saribaş, Mehmet Gül, Sevgi̇ İrtegün, Engi̇n Deveci̇
Turkish Journal of Medical Sciences
Background/aim: In this experimental study, we aimed to evaluate the late period effects of the combination of Ankaferd Blood Stopper (ABS), which has bone wound healing effects, and ß-tricalcium phosphate (TCP) on the regeneration of bone tissue through histopathological, immunohistochemical, and radiological (dual energy X-ray absorptiometry - DEXA) methods in nondiabetic rats. Materials and methods: Sixty-four Wistar albino male rats were used. In the calvaria of the rats, a bone defect 7.0 mm in diameter was created. These rats were divided into 4 different groups. Group 1 was the control group without any treatment, a 0.125 mL B-TCP graft was …
Vascular Responses Of Aortic, Renal, And Uterine Arteries In Suramin-Induced Preeclampsia-Like Syndrome In Rats, Sebi̇le Güler Çeki̇ç, Edi̇p Güvenç Çeki̇ç, Di̇lek Baydar, Meral Tuncer, Güray Soydan
Vascular Responses Of Aortic, Renal, And Uterine Arteries In Suramin-Induced Preeclampsia-Like Syndrome In Rats, Sebi̇le Güler Çeki̇ç, Edi̇p Güvenç Çeki̇ç, Di̇lek Baydar, Meral Tuncer, Güray Soydan
Turkish Journal of Medical Sciences
Background/aim: Suramin is a potent angiogenesis inhibitor in rodents and attenuates placental development in rat pregnancy. We aimed to produce preeclampsia-like syndrome by suramin administration in rats and to investigate the functional responses in aortic, renal, and uterine arteries. Materials and methods: Pregnant and nonpregnant wistar rats received suramin (100 mg/kg, intraperitoneal) or equal volume of saline on days 10 and 11. Blood pressures of rats were observed daily. On the day 20, rats were executed. Protein levels in urine were measured and fetuses, placentas, and kidneys were weighted and evaluated. Thoracic aorta, renal, and uterine arteries were removed for …
Spalax Denizliensis Sp. Nov. (Spalacidae, Rodentia) From An Early Pleistocene-Aged Locality In The Denizli Basin (Southwestern Turkey), Hüseyi̇n Erten
Spalax Denizliensis Sp. Nov. (Spalacidae, Rodentia) From An Early Pleistocene-Aged Locality In The Denizli Basin (Southwestern Turkey), Hüseyi̇n Erten
Turkish Journal of Zoology
It is thought that Spalacidae (Rodentia, Mammalia) originated in Anatolia. They are widespread among Neogene-aged faunas in Anatolia and they are used as zonal fossils because of their strong evolutionary dynamics. Only one fossil species (S. odessanus, Middle Pliocene) has been identified from the genus Spalax, which has more than 14 species presently. There are no fossil findings of this genus in Anatolia. Early Pleistocene-aged Spalax denizliensis sp. nov. from the Denizli Basin is the youngest fossil Spalax species and it will be helpful to understand the evolution of recent Spalax species.
A New Ostracoda (Crustacea) Genus, Comalcandona Gen. Nov., From Texas, Usa, Okan Külköylüoğlu, Randy Gibson
A New Ostracoda (Crustacea) Genus, Comalcandona Gen. Nov., From Texas, Usa, Okan Külköylüoğlu, Randy Gibson
Turkish Journal of Zoology
A new freshwater ostracod genus, Comalcandona gen. nov., and its type species (Comalcandona tressleri sp. nov.) are described from John Knox Ranch, Comal County, Texas, USA. The new genus differs from the related genera in the presence of the shallow pits on the trapezoidal shape of the carapace and presence of one well-developed anterior claw (posterior claw and both anterior and posterior setae are absent) on the uropod, a diagnostic character. Differences in the structure of the hemipenes, length and numbers of setae on the extremities, and shape of some other soft body parts also separate this genus from the …
Tardigrada Of Bory Tucholskie National Park, Zaborski Landscape Park, And Their Surroundings (Pomerania Province, Poland), Lukasz Kaczmarek, Jakub Kosicki, Milena Roszkowska
Tardigrada Of Bory Tucholskie National Park, Zaborski Landscape Park, And Their Surroundings (Pomerania Province, Poland), Lukasz Kaczmarek, Jakub Kosicki, Milena Roszkowska
Turkish Journal of Zoology
In this paper, samples of mosses and lichens collected from Bory Tucholskie National Park, Zaborski Landscape Park, and their surroundings (Pomerania Province, northern Poland) were studied for water bears (Tardigrada). In total, 38 tardigrade taxa were identified and six of them (Hypsibius cf. allisoni, Hyp. scabropygus, Macrobiotus sottilei, Milnesium beasleyi, Mil. dornensis, and Mil. granulatum) are new records for the Polish fauna. Eighteen taxa (only 14 identified to the species level) were found in Bory Tucholskie National Park, whereas in Zaborski Landscape Park this number was much larger, i.e. 28 taxa (including 22 identified to the species level), as well …
Feeding Dynamics And Performance Of Beetal Does In Relation To Body Condition Score At The Time Of Mating, Arpan Sharma, Sandeep Kaswan, S. Siva Kumar, Jaspal Singh Lamba
Feeding Dynamics And Performance Of Beetal Does In Relation To Body Condition Score At The Time Of Mating, Arpan Sharma, Sandeep Kaswan, S. Siva Kumar, Jaspal Singh Lamba
Turkish Journal of Veterinary & Animal Sciences
The body condition of does at the time of mating may affect feeding patterns and production performance during forthcoming lactation. For investigation, 40 Beetal does available for breeding were utilized, and their body condition score (BCS) was estimated using the visual-cum-palpation method with a 9-point scale (scale of 1=5 with increments of 0.5 point). The available goats were divided into 3 groups: higher BCS (T$_{≥3.0}$; n =11), moderate BCS (T$_{2.5}$; n = 8), and lower BCS (T$_{≤2.0}$; n = 21) and maintained in 2 random groups (20 each). Beetal goats with higher BCS at breeding time spent significantly (P < 0.01) more time feeding comfortably and less time feeding with difficulty than moderate and lower BCS goats. T2.5 and T$_{≤2.0}$ goats struggled (displacement and pushing) more at feeders, which included T$_{≤2.0}$ goats eating from the ground for more time (P < 0.01) than the other groups. T$_{≥3.0}$ goats had more agonistic interactions (threatening and hitting) toward moderate and lower BCS goats at feeders. Goats with higher BCS at mating had significantly (P < 0.05) higher milk yield during subsequent lactation; however, the composition of the milk did not differ among the groups. Mean disease incidence rate and number of days of disease per goat were significantly (P < 0.01) lesser in the T$_{≥3.0}$ group than other groups. It was concluded that Beetal goats should not have less than 3.0 BCS at the time of mating for better performance and health status.
Morphological Diagnosis Of Johne?S Disease: A Case Report In Cattle, Siddharth Gautam, Chitra Joshi, Amol Gurav, Chandrakanta Jana, Anil Kumar Sharma
Morphological Diagnosis Of Johne?S Disease: A Case Report In Cattle, Siddharth Gautam, Chitra Joshi, Amol Gurav, Chandrakanta Jana, Anil Kumar Sharma
Turkish Journal of Veterinary & Animal Sciences
The present case report deals with the morphological (gross and histopathological) and histochemical characterization of Johne?s disease in a cow. The carcass was presented in a hidebound condition with sunken eyes and with a history of persistent and nonresponsive diarrhea. Necropsy revealed generalized gelatinization of the visceral and peripheral fat. Thorough gross examination unveiled major pathological changes in the digestive tract. The gallbladder was distended, with severely thickened walls and blood mixed with bile. The small intestine was severely congested and the mesenteric lymph nodes were enlarged. The opening of the small intestine showed marked thickening of the intestinal walls, …
The First-Time Isolation Of Brucella Canis From Two Aborted Bitches In A Kennel In Turkey, Ahmet Murat Sayteki̇n, Mustafa Sencer Karagül, Buket Altuntaş, Gülseren Yildiz Öz, Gülnaz Meci̇toğlu, Özge Yilmaz
The First-Time Isolation Of Brucella Canis From Two Aborted Bitches In A Kennel In Turkey, Ahmet Murat Sayteki̇n, Mustafa Sencer Karagül, Buket Altuntaş, Gülseren Yildiz Öz, Gülnaz Meci̇toğlu, Özge Yilmaz
Turkish Journal of Veterinary & Animal Sciences
Brucella canis is defined as the specific agent that is responsible for canine brucellosis. In this study, B. canis was isolated and identified from the clinical materials belonging to 2 dogs kept in a breeding kennel in Turkey and brought to the researchers? clinic with abortion complaints. With this study, for the first time ever, B. canis isolation and identification was made from dogs that aborted in a kennel. This study emphasizes
Impacts Of Environmental Factors On Zooplankton Taxonomic Diversity In Coastal Lagoons In Turkey, Nuray Akbulut, Ülkü Ni̇han Tavşanoğlu
Impacts Of Environmental Factors On Zooplankton Taxonomic Diversity In Coastal Lagoons In Turkey, Nuray Akbulut, Ülkü Ni̇han Tavşanoğlu
Turkish Journal of Zoology
Lagoons are valuable ecosystems providing various services, such as fishing, recreational activities, and land reclamation, as well as hosting high biodiversity. Although lagoons in Turkey cover a coastal area of more than 36,000 ha, few studies of them have been conducted. Therefore, two lagoons (Dalyan and Arapçiftliği) located on the coast of the Sea of Marmara in the Kocaçay Delta, which is under intense anthropogenic pressure, were investigated between November 2013 and March 2015 to examine the effects of environmental factors on taxonomic diversity. In addition, ongoing high nutrient flow from the Karacabey region triggers eutrophication in the lagoons, thus …
Morphological Variation Of Pumpkinseed (Lepomis Gibbosus) With Emphasis On Allometry, Fati̇h Mangit, Mustafa Korkmaz, Sedat Vahdet Yerli̇
Morphological Variation Of Pumpkinseed (Lepomis Gibbosus) With Emphasis On Allometry, Fati̇h Mangit, Mustafa Korkmaz, Sedat Vahdet Yerli̇
Turkish Journal of Zoology
Pumpkinseed(Lepomis gibbosus)is an exotic fish species widely distributed in Europe and it has expanded its distribution area in Turkey since its first report in 1982. It is well known that invasive species like L. gibbosus adapt to introduced habitats relatively well. In order to evaluate morphological variation within this invasive species, sampling was carried out in June 2012 and May 2013 in the Aegean and Thrace regions, respectively. Body-form variability in sampled populations of L. gibbosus was investigated using landmark-based geometric morphometrics. L. gibbosus showed significant geographic- and habitat-based differences with and without allometric standardization. However, outcomes of these results …
Variations In Afrolaophonte Pori Masry, 1970 (Copepoda: Harpacticoida: Laophontidae): A Contribution Towards The Revision Of The Genus, Serdar Sönmez, Süphan Karaytuğ, Serdar Sak, Alp Alper
Variations In Afrolaophonte Pori Masry, 1970 (Copepoda: Harpacticoida: Laophontidae): A Contribution Towards The Revision Of The Genus, Serdar Sönmez, Süphan Karaytuğ, Serdar Sak, Alp Alper
Turkish Journal of Zoology
Afrolaophonte pori was originally described from the interstitial habitats of Israel and subsequently reported from Italy and the Aegean coasts of Turkey. It is the only representative of the genus in the Mediterranean Sea. The aim of this study is to present a detailed redescription of A. pori based on extensive material from different parts of the species' range to provide geographic distributional data and to reveal variations within and between the populations. We have examined numerous specimens collected from the Aegean and Mediterranean Turkish coasts and have presented a detailed redescription of both sexes. Despite the fact that the …
Distribution And Diversity Of Earthworm (Annelida, Clitellata)Populations Across Four Land Use Types In Northern Cameroon, Michel Mathurin Kamdem, Patricks Voua Otomo, Albert Ngakou, Nicolas Njintang Yanou
Distribution And Diversity Of Earthworm (Annelida, Clitellata)Populations Across Four Land Use Types In Northern Cameroon, Michel Mathurin Kamdem, Patricks Voua Otomo, Albert Ngakou, Nicolas Njintang Yanou
Turkish Journal of Zoology
Earthworms are present in all types of soil. Changes in land use influence populations of earthworms. However, information on the dynamics of earthworm populations in northern Cameroon is not available. This paper highlights the research carried out on the abundance, biomass, and diversity of earthworm populations throughout four types of land use in northern Cameroon. Earthworms were sampled throughout the rainy season in three regions, across pastures, woody savannahs, grass savannahs, and fields, using formaldehyde and hand sorting. Earthworms of the woody savannah and pasture have a high mean density (63 and 45 individuals/m2, respectively) and biomass (25.2 and 22 …
A Comprehensive Phylogenetic Analysis Of Grapsoidea Crabs (Decapoda: Brachyura) Based On Mitochondrial Cytochrome Oxidase Subunit 1 (Co1) Genes, Zhaozhe Xin, Yu Liu, Boping Tang, Chunlin Zhou, Qiuning Liu
A Comprehensive Phylogenetic Analysis Of Grapsoidea Crabs (Decapoda: Brachyura) Based On Mitochondrial Cytochrome Oxidase Subunit 1 (Co1) Genes, Zhaozhe Xin, Yu Liu, Boping Tang, Chunlin Zhou, Qiuning Liu
Turkish Journal of Zoology
The sequences of mitochondrial cytochrome c oxidase subunit I (CO1) genes of eight species crabs of Grapsoidea were determined and analyzed in this paper. The traditional classification is that Grapsidae contains four subfamilies comprising Grapsinae, Varuninae, Sesarminae, and Plagusiinae, which are also treated as families in some studies. There is a lack of clarity in the classification of some species, such as Eriocheir species. In this study, we conducted the first exploration of evolutionary relationships among species based on analysis of the molecular data of CO1 genes of eight species (Sesarmops sinensis, Clistocoeloma sinensis, Perisesarma bidens, Helice latimera, Helice tientsinensis, …
Parasitoids Reared From Galls Of Stefaniola Sp. (Diptera, Cecidomyiidae) On Haloxylon Spp. In China, With Redescription Of Mesopolobus Quadrimaculatus Dzhanokmen (Chalcidoidea, Pteromalidae), Qin Li, Klarissa Alekseyevna Dzhanokmen, Serguei Vladimirovich Triapitsyn, Hongying Hu
Parasitoids Reared From Galls Of Stefaniola Sp. (Diptera, Cecidomyiidae) On Haloxylon Spp. In China, With Redescription Of Mesopolobus Quadrimaculatus Dzhanokmen (Chalcidoidea, Pteromalidae), Qin Li, Klarissa Alekseyevna Dzhanokmen, Serguei Vladimirovich Triapitsyn, Hongying Hu
Turkish Journal of Zoology
Mesopolobus quadrimaculatus Dzhanokmen (Hymenoptera: Pteromalidae) is recorded for the first time from China and outside of Kazakhstan. It was reared from galls of Stefaniola sp. (Diptera: Cecidomyiidae) on black saxaul, Haloxylon ammodendron (C.A.Mey.) Bunge ex Fenzl and white saxaul, H. persicum (Bunge ex Boiss. & Buhse) (Chenopodiaceae) in Beishawo Desert in Fukang, Xinjiang Uyghur Autonomous Region, China. Provided are its illustrated redescription and diagnosis, which was not included in the original escription, as well as data on the distribution and biology of this interesting, little known species. Mesopolobus deserti Dzhanokmen, which is also newly recorded from China, was swept on …
The First Annotated Checklist Of Mayflies (Ephemeroptera: Insecta) Of Georgia With New Distribution Data And A New Record For The Country, Sophio Gabelashvili, Levan Mumladze, Ani Bikashvili, Pavel Sroka, Roman J. Godunko, Bella Japoshvili
The First Annotated Checklist Of Mayflies (Ephemeroptera: Insecta) Of Georgia With New Distribution Data And A New Record For The Country, Sophio Gabelashvili, Levan Mumladze, Ani Bikashvili, Pavel Sroka, Roman J. Godunko, Bella Japoshvili
Turkish Journal of Zoology
The first comprehensive checklist of mayflies (Ephemeroptera) of Georgia is provided based on literature data supplemented by our unpublished data, including extensive samples in 2013-2017, works with the collections and types, faunistic observations, and taxonomical contributions. Records of 75 species are provided, with one species reported as a new finding for the country. Notes about the taxonomic status of several species are given. The present contribution represents the first publication of this kind for mayflies within the whole Caucasus area.
Benthic Invertebrates Associated With Subfossil Cold-Water Coral Frames And Hardgrounds In The Albanian Deep Waters (Adriatic Sea), Ina Nasto, Frine Cardone, Francesco Mastrototaro, Piero Panetta, Antonietta Rosso, Rosanna Sanfilippo, Marco Taviani, Angelo Tursi
Benthic Invertebrates Associated With Subfossil Cold-Water Coral Frames And Hardgrounds In The Albanian Deep Waters (Adriatic Sea), Ina Nasto, Frine Cardone, Francesco Mastrototaro, Piero Panetta, Antonietta Rosso, Rosanna Sanfilippo, Marco Taviani, Angelo Tursi
Turkish Journal of Zoology
The fauna collected associated with subfossil Lophelia pertusa and Dendrophyllia cornigera coral samples and hardgrounds from Albanian waters between 190?230 m is discussed. Eighty-three benthic species are recorded: 2 Foraminifera, 22 Porifera, 6 Cnidaria, 25 Mollusca, 14 Annelida, 1 Arthropoda, 12 Bryozoa, and 1 Echinodermata. Seventy-four species are new records for the poorly investigated Albanian deep waters.
A New Species Of The Genus Microliobunum From Turkey (Opiliones, Sclerosomatidae), Kemal Kurt
A New Species Of The Genus Microliobunum From Turkey (Opiliones, Sclerosomatidae), Kemal Kurt
Turkish Journal of Zoology
A new harvestman species, Microliobunum erseni sp. nov., is described and illustrated with photographs of both sexes from Kilis Province, Turkey. It is the second species in this genus, which is otherwise known only from Lebanon.
Influence Of Tree Thinning On Abundance And Survival Probability Of Small Rodents In A Natural Deciduous Forest, Jae-Kang Lee, Hyun-Su Hwang, Tae-Kyung Eom, Shin-Jae Rhim
Influence Of Tree Thinning On Abundance And Survival Probability Of Small Rodents In A Natural Deciduous Forest, Jae-Kang Lee, Hyun-Su Hwang, Tae-Kyung Eom, Shin-Jae Rhim
Turkish Journal of Zoology
This study was conducted to investigate the influence of tree thinning on habitat variables and small rodents in a natural deciduous forest in South Korea. We focused on the populations of the small forest-dwelling rodents, striped field mouse Apodemus agrarius and Korean field mouse A. peninsulae. Populations were monitored for 2 years in a natural deciduous forest subject to tree thinning. The coverage of ground vegetation and number and volume of downed trees were significantly increased after thinning. However, the coverage of overstory and understory vegetation and number of standing trees were decreased in postthinning session. The abundance and survival …
Effects Of Genetic Relatedness, Spatial Distance, And Context On Intraspecificaggression In The Red Wood Ant Formica Pratensis (Hymenoptera: Formicidae), Volkan Aksoy, Yilmaz Çamlitepe
Effects Of Genetic Relatedness, Spatial Distance, And Context On Intraspecificaggression In The Red Wood Ant Formica Pratensis (Hymenoptera: Formicidae), Volkan Aksoy, Yilmaz Çamlitepe
Turkish Journal of Zoology
In the present study, we tested the level of aggression of monodomous and polydomous colonies of the wood ant Formica pratensis (Hymenoptera: Formicidae) with a behavioral assay in nature and laboratory conditions to see if the ants from neighboring colonies are more tolerant or more aggressive to each other than those from greater distances. We also tested how context (nature and laboratory conditions) affected aggression. Our results showed that the monodomous colonies were highly aggressive to all neighboring or nonneighboring conspecifics in nature irrespective of the spatial distance. The polydomous colony showed no aggression towards neighboring conspecifics but the level …
Lichens In The Nests Of European Starling Sturnus Vulgaris Serve A Mate Attraction Rather Than Insecticidal Function, Lucia Mariel Ibañez, Renato Andres García, Vanina Dafne Fiorini, Diego Montalti
Lichens In The Nests Of European Starling Sturnus Vulgaris Serve A Mate Attraction Rather Than Insecticidal Function, Lucia Mariel Ibañez, Renato Andres García, Vanina Dafne Fiorini, Diego Montalti
Turkish Journal of Zoology
The European starling Sturnus vulgaris is a hole-nesting bird in which the male builds a voluminous nest using a wide variety of materials such as twigs, grass, leaves, feathers, and lichens. The function of lichens in starling nests has not been assessed until now and we hypothesize that this material is related to a mate attraction function or is used to protect nestlings from parasites due to the presence of secondary compounds with insecticidal effects with the lichens. We aimed to identify the lichen species and frequency of lichen use in European starling nests, and to determine if the presence …
Adsorption Of Anionic And Cationic Dyes On Biochars, Produced By Hydrothermalcarbonization Of Waste Biomass: Effect Of Surface Functionalization And Ionicstrength, Ezgi̇ Çağlar, Yusuf Osman Donar, Ali̇ Sinağ, İbrahi̇m Bi̇roğul, Selva Bi̇lge, Kivanç Aydincak, Oleksii Pliekhov
Adsorption Of Anionic And Cationic Dyes On Biochars, Produced By Hydrothermalcarbonization Of Waste Biomass: Effect Of Surface Functionalization And Ionicstrength, Ezgi̇ Çağlar, Yusuf Osman Donar, Ali̇ Sinağ, İbrahi̇m Bi̇roğul, Selva Bi̇lge, Kivanç Aydincak, Oleksii Pliekhov
Turkish Journal of Chemistry
In this work, surface-functionalization agents and various salts as auxiliaries were used to improve the adsorption capacity of biochars produced via hydrothermal carbonization of glucose, cellulose, and hazelnut shell. The effect of surface functionalization with different acids and bases as well as neutral salts on the adsorption of methylene blue and methyl orange was investigated using Boehm titration, Fourier transform infrared spectroscopy, and X-ray photoelectron spectroscopy techniques. Surface functionalization of biochars leads to an increase in the number of oxygen-containing functional groups on the surface, thus increasing the adsorption capacity. To probe the influence of ionic strength on the adsorption …
The Synthesis Of New Oxindoles As Analogs Of Natural Product 3,3$^\Prime $-Bis(Indolyl)Oxindole And In Vitro Evaluation Of The Enzyme Activity Of G6pd And 6pgd, Si̇nan Bayindir, Adnan Ayna, Yusuf Temel, Mehmet Çi̇ftci̇
The Synthesis Of New Oxindoles As Analogs Of Natural Product 3,3$^\Prime $-Bis(Indolyl)Oxindole And In Vitro Evaluation Of The Enzyme Activity Of G6pd And 6pgd, Si̇nan Bayindir, Adnan Ayna, Yusuf Temel, Mehmet Çi̇ftci̇
Turkish Journal of Chemistry
Natural and synthetic derivatives that contain an indole core are being used in medical treatments and technological processes. Therefore, the development of new synthetic methods for the synthesis of indole derivatives is very popular. In this study, new oxindoles with reaction of 4,7-dihydro-1$H$-indole (2) and isatin (4) were synthesized as analogs of natural product 3,3$^\prime $-bis(indolyl)oxindole. The biological properties of the compounds obtained during this study were also studied, showing that compounds 5, 7, and 12 inhibited the activity of G6PD with an IC$_{50}$ of 99 $\mu $M, 231 $\mu $M, and 304 $\mu $M respectively. The activity of rat …
Photocatalytic Degradation Of The Herbicide Quinclorac In Water Using Mn (Iii) Salen And Solar Light, Yisi Yang, Yan Zhang, Qingru Zeng
Photocatalytic Degradation Of The Herbicide Quinclorac In Water Using Mn (Iii) Salen And Solar Light, Yisi Yang, Yan Zhang, Qingru Zeng
Turkish Journal of Chemistry
Quinclorac (QNC) is a widely used herbicide and is persistent in surface and ground waters. Its residuals and converted products are hazardous to aquatic animals, vegetation, and microbes, and it is therefore important to degrade QNC using an efficient and environmental friendly technology. In this study, the photocatalytical degradation of QNC using [(R,R)-(N,N$'$-bis(3,5,3$'$,5$'$-tetra-tert-butylsalicylidene)-1,2-cyclohexanediaminato] manganese(III) acetate (Mn (III) salen) and H$_{2}$O$_{2}$ was performed under natural sunlight irradiation and a 91% degradation rate was achieved in neutral pure water in 240 min. The identified degradation products confirmed that the cleavage of QNC molecules was the main process involved in the hydroxylation, along …
Recent Advances In Organ-On-A-Chip Technologies And Future Challenges: A Review, Hüseyi̇n Avci, Fatma Doğan Güzel, Sali̇m Erol, Ali̇ Akpek
Recent Advances In Organ-On-A-Chip Technologies And Future Challenges: A Review, Hüseyi̇n Avci, Fatma Doğan Güzel, Sali̇m Erol, Ali̇ Akpek
Turkish Journal of Chemistry
The significant development in the construction of microscale cell culture platforms and the interest in bioanalytical analysis have recently resulted in the emergence of a new concept of `organ-on-a-chip' systems. Organ-on-a-chip is a new three-dimensional (3D) in vitro microfabricated unit that contains a multichannel microfluidic cell culture. Even if many informative and useful data are obtained from animal models and in vitro assays, they are still limited for extrapolation to human systems during drug design and development. Only about 1 out of 10,000 compounds is processed in clinical trials for final approval. As being the first example of its kind, …
An Ionic Liquid/Bismuth Film-Modified Sensor For The Electrochemical Detection Of Cefixime, Yeşi̇m Tuğçe Yaman, Gülçi̇n Bolat, Ceren Yardimci, Serdar Abaci
An Ionic Liquid/Bismuth Film-Modified Sensor For The Electrochemical Detection Of Cefixime, Yeşi̇m Tuğçe Yaman, Gülçi̇n Bolat, Ceren Yardimci, Serdar Abaci
Turkish Journal of Chemistry
A highly sensitive and simple method based on an ionic liquid/ex situ bismuth film-modified single-use pencil graphite electrode (IL/Bi/PGE) was offered for the electrochemical detection of cefixime (CEF) for the first time. The synergistic effects of the ionic liquid and bismuth film combination as the surface modifier remarkably improved the electrochemical response of the modified sensor. Anodic oxidation of CEF was observed at 0.9 V vs. Ag/AgCl/3 M KCl as one well-defined irreversible oxidation peak. Under optimum experimental conditions, the IL/Bi/PGE exhibited a linear relationship for CEF concentrations in the range of 0.005--0.5 $\mu $M (R$^{2}$ = 0.996) with a …
Solid-Phase Extraction Method For Preconcentration Of Cadmium And Lead In Environmental Samples Using Multiwalled Carbon Nanotubes, Ayman A. Gouda, Wael A. Zordok
Solid-Phase Extraction Method For Preconcentration Of Cadmium And Lead In Environmental Samples Using Multiwalled Carbon Nanotubes, Ayman A. Gouda, Wael A. Zordok
Turkish Journal of Chemistry
A new sensitive and accurate solid-phase extraction method for preconcentration of trace amounts of cadmium and lead in various environmental samples prior to flame atomic absorption spectrometry determination has been developed. The proposed method is based on the utilization of multiwalled carbon nanotubes in combination with 5-benzyl-4-[-chlororbenzylidene amine]-4H-1,2,4-triazole-3-thiol (BCBATT) as a solid-phase sorbent with the aid of ultrasonication. The effect of the preconcentration parameters was investigated. Good recoveries ranging from 95% to 102% with relative standard deviations of 3.2% and 2.8% for Cd$^{2+}$ and Pb$^{2+}$, respectively, were obtained, indicating high accuracy and precision. The limits of detection were 0.2 and …
Exploring Inhibition Of Chemiluminescence Mechanisms With Fluorescence Quenching Studies And Interaction Energy Calculations, Zhenbo Liu, Tangmi Yuan, Yongming Liu, Wenzuo Li, Qingzhong Li, Bo Xiao, Jianbo Cheng
Exploring Inhibition Of Chemiluminescence Mechanisms With Fluorescence Quenching Studies And Interaction Energy Calculations, Zhenbo Liu, Tangmi Yuan, Yongming Liu, Wenzuo Li, Qingzhong Li, Bo Xiao, Jianbo Cheng
Turkish Journal of Chemistry
Carbamates weaken the luminol-H$_{2}$O$_{2}$ chemiluminescence (CL) catalyzed by sodium copper chlorophyll (SCC). The capacity to inhibit the CL of three carbamates is in the order of carbaryl (CBL) \textgreater carbofuran (CBF) \textgreater metolcarb (MTC). Mechanisms of carbamates inhibiting SCC-luminol-H$_{2}$O$_{2}$ CL are investigated using fluorescence quenching and quantum chemistry simulations for the first time in this work. Carbamate-SCC interactions studied using fluorescence spectroscopy show that with the increasing concentration of the SCC, the fluorescence of carbamate is quenched regularly, and the quenching mechanism is a static quenching process. Binding constants ($K_{B})$ of the three carbamates with SCC are CBL (4.39 x …