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Design And Development Of A Stewart Platform Assisted And Navigated Transsphenoidal Surgery, Selçuk Ki̇zi̇r, Zafer Bi̇ngül
Design And Development Of A Stewart Platform Assisted And Navigated Transsphenoidal Surgery, Selçuk Ki̇zi̇r, Zafer Bi̇ngül
Turkish Journal of Electrical Engineering and Computer Sciences
In this study, technical details of a Stewart platform (SP) based robotic system as an endoscope positioner and holder for endoscopic transsphenoidal surgery are presented. Inverse and forward kinematics, full dynamics, and the Jacobian matrix of the robotic system are derived and simulated in MATLAB/Simulink. The required control structure for the trajectory and position control of the SP is developed and verified by several experiments. The robotic system can be navigated using a six degrees of freedom (DOF) joystick and a haptic device with force feedback. Position and trajectory control of the SP in the joint space is achieved using …
A New Spectral Estimation-Based Feature Extraction Method For Vehicle Classification In Distributed Sensor Networks, Erdem Köse, Ali̇ Köksal Hocaoğlu
A New Spectral Estimation-Based Feature Extraction Method For Vehicle Classification In Distributed Sensor Networks, Erdem Köse, Ali̇ Köksal Hocaoğlu
Turkish Journal of Electrical Engineering and Computer Sciences
Ground vehicle detection and classification with distributed sensor networks is of growing interest for border security. Different sensing modalities including electro-optical, seismic, and acoustic were evaluated individually and in combination to develop a more efficient system. Despite previous works that mostly studied frequency-domain features and acoustic sensors, in this work we analyzed the classification performance for both frequency and time-domain features and seismic and acoustic modalities. Despite their infrequent use, we show that when fused with frequency-domain features, time-domain features improve the classification performance and reduce the false positive rate, especially for seismic signals. We investigated the performance of seismic …
Attempts To Save A Spanish Endemism Astragalus Devesae Talavera, A. González & G. López (Fabaceae) From Extinction, Karoline Aparecida Felix Ribeiro, José Ángel Sánchez Agudo, Silvia Sánchez Durán, Ester Vega Elices, José Sánchez Sánchez
Attempts To Save A Spanish Endemism Astragalus Devesae Talavera, A. González & G. López (Fabaceae) From Extinction, Karoline Aparecida Felix Ribeiro, José Ángel Sánchez Agudo, Silvia Sánchez Durán, Ester Vega Elices, José Sánchez Sánchez
Turkish Journal of Botany
Astragalus devesae Talavera, A. González & G. López (Fabaceae) is a threatened Hispanic endemic species whose distribution is restricted to the center of Spain (the province of Ávila). It is classified as ?Critically Endangered? in the 2010 List of Threatened Spanish Vascular Flora and as ?Endangered? in the ?Decree 63/2007? of Castile and Leon (administrative region in which Ávila is included). In this study, censuses of three existing populations were carried out and one of these that was found along the course of this work, was ecologically characterized. High interpopulation variability (0%, 26%, and 73%) was observed with respect to …
G-Quadruplex Enrichment Analysis Reveals Their Role As Intronic Regulatory Elements In Plants, Osman Doluca
G-Quadruplex Enrichment Analysis Reveals Their Role As Intronic Regulatory Elements In Plants, Osman Doluca
Turkish Journal of Botany
G-Quadruplexes, a class of noncanonical but highly stable nucleic acid structures, have the potential to be part of the regulatory mechanism of cells. They can form in the genome where the double-stranded helix is unwound to facilitate formation of a G-quadruplex. The biological significance of these structures is yet to be understood entirely. This work presents a novel approach and investigates common characteristics in the distribution of G-quadruplexes relative to genes in plants through analysis of genomes and gene expressions. The results indicate that G-quadruplex distribution has gone through significant changes with the evolution of higher plants and, for the …
In Silico Design And In Vitro Development Of A Highly Accurate Test To Detect Brucella Species, Hosein Safari, Setareh Shahnazari, Maysam Mard-Soltani, Somayeh Tavakoli, Bahman Khalesi
In Silico Design And In Vitro Development Of A Highly Accurate Test To Detect Brucella Species, Hosein Safari, Setareh Shahnazari, Maysam Mard-Soltani, Somayeh Tavakoli, Bahman Khalesi
Turkish Journal of Medical Sciences
Background: Conventionalmethods of detecting Brucella spp. suffer from technical and biological complications. Besides, newly characterized species of the genus Brucella could be neglected by previously designed polymerase chain reaction (PCR) tests. Therefore, a more accurate PCR-based test seems to be imminently needed. Materials and methods: Blood samples were collected from 39 patients diagnosed with brucellosis and 25 healthy controls. Multiple sequence alignments (MSA) were performed on 500 Omp2-related protein and gene sequences. Thereafter, specific primers were designed and synthesized for the regions with highest conservancy. The collected samples were assessed by PCR test. To overcome the cross-reactivity issue, PCR thermal …
Serum Prolidase Level In Patients With Brucellosis And Its Possible Relationship With Pathogenesis Of The Disease: A Prospective Observational Study, Oğuzhan Sitki Di̇zdar, Ayşe Turunç Özdemi̇r, Osman Başpinar, Derya Koçer, Yavuz Katircilar, İlhami̇ Çeli̇k
Serum Prolidase Level In Patients With Brucellosis And Its Possible Relationship With Pathogenesis Of The Disease: A Prospective Observational Study, Oğuzhan Sitki Di̇zdar, Ayşe Turunç Özdemi̇r, Osman Başpinar, Derya Koçer, Yavuz Katircilar, İlhami̇ Çeli̇k
Turkish Journal of Medical Sciences
Background/aim: Changes in collagen metabolism and fibroblastic activity may play a role in the pathogenesis of brucellosis. The prolidase enzyme plays an important role in collagen synthesis. We aimed to investigate the association of prolidase levels with brucellosis.Materials and methods: Serum prolidase levels in 20 patients newly diagnosed with brucellosis were compared with levels in 30 healthy control subjects. Patients with brucellosis were reassessed 3 months later for prolidase, other laboratory measurements, and response to treatment. Results: The levels of serum prolidase were significantly higher in brucellosis patients compared with those of healthy controls. Prolidase, sedimentation, and C-reactive protein levels …
Effects Of Phenytoin Injection On Vocal Cord Healing After Mechanical Trauma: An Experimental Study, Si̇bel Ali̇cura Tokgöz, Cem Saka, İstemi̇han Akin, Fatma Fulya Köybaşioğlu, Saffet Kiliçaslan, Murat Çalişkan, Ömer Beşalti, Emel Çadalli Tatar
Effects Of Phenytoin Injection On Vocal Cord Healing After Mechanical Trauma: An Experimental Study, Si̇bel Ali̇cura Tokgöz, Cem Saka, İstemi̇han Akin, Fatma Fulya Köybaşioğlu, Saffet Kiliçaslan, Murat Çalişkan, Ömer Beşalti, Emel Çadalli Tatar
Turkish Journal of Medical Sciences
Background/aim: Phenytoin is an anticonvulsant drug which causes fibroblast proliferation, collagen synthesis, and an increase in epidermal growth factor. Therefore, the aim of the present study is to evaluate the effect of phenytoin injection on the wound healing process in rats with vocal cord injury by histopathological methods. Materials and methods: The vocal cords of 10 albino Wistar rats were damaged bilaterally; the left vocal cord was kept as the control group. Phenytoin was injected in the right vocal cord. Ten rats were sacrificed. The thickness of the lamina propria and density of the fibroblast and collagen were evaluated histopathologically.Results: …
Tricholoma (Fr.) Staude In The Aegean Region Of Turkey, İsmai̇l Şen, Hakan Alli
Tricholoma (Fr.) Staude In The Aegean Region Of Turkey, İsmai̇l Şen, Hakan Alli
Turkish Journal of Botany
The Tricholoma biodiversity of the Aegean region of Turkey has been determined and reported in this study. As a consequence of field and laboratory studies, 31 Tricholoma species have been identified, and five of them (T. filamentosum, T. frondosae, T. quercetorum, T. rufenum, and T. sudum) have been reported for the first time from Turkey. The identification key of the determined taxa is given with this study.
Cytotoxic And Genotoxic Action Of Tagetes Patula Flower Methanol Extract And Patuletin Using The Allium Test, Mudassar Azhar, Ahsana Dar Farooq, Sayedul Haque, Samina Bano, Lubna Zaheer, Shaheen Faizi
Cytotoxic And Genotoxic Action Of Tagetes Patula Flower Methanol Extract And Patuletin Using The Allium Test, Mudassar Azhar, Ahsana Dar Farooq, Sayedul Haque, Samina Bano, Lubna Zaheer, Shaheen Faizi
Turkish Journal of Biology
Tagetes patula is used to treat cancer patients in alternative healthcare systems. However, its cytotoxic and genotoxic effects have not been reported. Therefore, the methanol extract of T. patula flower, the ethyl acetate fraction, and the pure compound patuletin were evaluated using the Allium test. The methanol extract and fraction contained ~3% and ~36% patuletin, respectively, with ~98% purity. The methanol extract caused inhibition of Allium root growth displaying an IC50 value of ~500 μg/mL, while the fraction and patuletin were more potent by ~2 and ~5 times, respectively. The Allium root tips demonstrated a decline in prophase, metaphase, anaphase, …
Late Quaternary Landscape Evolution Of The Southern Marmara Region:Paleogeographic Implications For Settlements, Nw Turkey, Ni̇zametti̇n Kazanci, Zeynep Ergun, Kaan İren, Suzanne A. Leroy, Sonay Boyraz Aslan, Mehmet Sali̇m Öncel, Koray Koç, Alper Gürbüz
Late Quaternary Landscape Evolution Of The Southern Marmara Region:Paleogeographic Implications For Settlements, Nw Turkey, Ni̇zametti̇n Kazanci, Zeynep Ergun, Kaan İren, Suzanne A. Leroy, Sonay Boyraz Aslan, Mehmet Sali̇m Öncel, Koray Koç, Alper Gürbüz
Turkish Journal of Earth Sciences
This study presents the late Quaternary evolution of the southern Marmara region in northwestern Turkey and discusses the suitability of the area for settlements. It is based on interpretation of sediment analyses together with radiometric dates obtained from drilling cores. As three-fourths of the southern Marmara region (ca. 30,000 km2) is covered by the Susurluk Drainage Basin (SDB), the study focuses on this basin. The SDB has a concave surface morphology dipping northward, with highlands in the south (ca. 1300-1700 m a.s.l.) and lowlands in the north (ca. 0-250 a.s.l.). Lake Manyas, Lake Ulubat, and south-north flowing rivers, together with …
Genetic Diversity, Phylogeography And Population Gene Flow Of Tunisian Pistacia Vera L., Sarra Choulak, Zined Marzouk, Khaled Chatti̇, Soumaya Rhouma-Chatti̇, Rim Ouni̇, Noureddine Chatti
Genetic Diversity, Phylogeography And Population Gene Flow Of Tunisian Pistacia Vera L., Sarra Choulak, Zined Marzouk, Khaled Chatti̇, Soumaya Rhouma-Chatti̇, Rim Ouni̇, Noureddine Chatti
Turkish Journal of Botany
The aim of this paper was to determine how the pistachio trees evolve, and the evolving factors that influence pistachio population establishment. For that, we investigated pistachio genetic structure from some regions of Tunisia, by sequencing two noncoding chloroplastic regions (trnL (UAA) and trnL-trnF intergenic spacer). We found strong genetic diversity among groups, with the absence of high differentiation between population pairs. A deep phylogeographical break separated two major clusters: "El-Guetar and "Gafsa/Sidi-Bouzid. This conclusion is proved by the haplotype networks, the phylogenetic trees, and the molecular variance analysis. Different interpretations were proposed to explain this cytoplasm dimorphism, based on …
Folk Medicine In Düzce Province (Turkey), İlhan Gürbüz, Ayşe Mi̇ne Gençler Özkan, Gali̇p Akaydin, Ece Sali̇hoğlu, Tuğba Günbatan, Fati̇h Demi̇rci̇, Erdem Yeşi̇lada
Folk Medicine In Düzce Province (Turkey), İlhan Gürbüz, Ayşe Mi̇ne Gençler Özkan, Gali̇p Akaydin, Ece Sali̇hoğlu, Tuğba Günbatan, Fati̇h Demi̇rci̇, Erdem Yeşi̇lada
Turkish Journal of Botany
The present study was conducted to collect, record, and document local knowledge of medicinal practices in Düzce, a northwestern Anatolian province. To the best of our knowledge, no comprehensive ethnobotanical study has been reported from this province. Information was acquired through semistructured interviews and personal conversations using a questionnaire and numerous guided field trips with local knowledgeable people. For quantitative analyses and comparisons, recorded data such as informant consensus factor (FIC) and use value (UV) were calculated, respectively. As a result of extensive field studies, 122 taxa were determined as folk medicines; 76 of were wild and 46 were cultivated. …
Squalene Attenuates The Oxidative Stress And Activates Akt/Mtor Pathway Against Cisplatin-Induced Kidney Damage In Mice, Ayşe Arzu Şakul, Mehmet Ozansoy, Bi̇rsen Eli̇bol, Şule Ayla, Mehmet Yalçin Günal, Yasemi̇n Yozgat, Selma Hüveyda Başağa, Kazi̇m Şahi̇n, Rümeyza Kazancioğlu, Ülkan Kiliç
Squalene Attenuates The Oxidative Stress And Activates Akt/Mtor Pathway Against Cisplatin-Induced Kidney Damage In Mice, Ayşe Arzu Şakul, Mehmet Ozansoy, Bi̇rsen Eli̇bol, Şule Ayla, Mehmet Yalçin Günal, Yasemi̇n Yozgat, Selma Hüveyda Başağa, Kazi̇m Şahi̇n, Rümeyza Kazancioğlu, Ülkan Kiliç
Turkish Journal of Biology
The clinical use of cisplatin, which is a first-line anticancer agent, is highly restricted due to its adverse effects on kidneys that lead to nephrotoxicity. Therefore, some potential reno-protective substances have been used in combination with cisplatin to cope with nephrotoxicity. Due to its high antitumor activity and oxygen-carrying capacity, we investigated the molecular effects of squalene against cisplatin-induced oxidative stress and kidney damage in mice. Single dose of cisplatin (7 mg/kg) was given to male Balb/c mice. Squalene (100 mg/kg/day) was administered orogastrically to mice for 10 days. Following sacrification, molecular alterations were investigated as analysis of the levels …
A Modified Gravitational Search Algorithm And Its Application In Lifetime Maximization Of Wireless Sensor Networks, Sepehr Ebrahimi Mood, Mohammad Masoud Javidi
A Modified Gravitational Search Algorithm And Its Application In Lifetime Maximization Of Wireless Sensor Networks, Sepehr Ebrahimi Mood, Mohammad Masoud Javidi
Turkish Journal of Electrical Engineering and Computer Sciences
Recently, academic communities and industrial sectors have been affected by significant advancements in wireless sensor networks (WSNs). Employing clustering methods is the dominant method to maximize the WSN's lifetime, which is considered to be a major issue. Metaheuristic algorithms have attracted wide attention in the research area of clustering. In this paper, first a novel nature-inspired optimization algorithm based on the gravitational search algorithm (GSA) is defined. To control the exploitation and exploration capabilities of this algorithm, along with calculating the masses value, the tournament selection method is employed. Tournament size, the parameter of this method, is computed automatically using …
Improving Word Embeddings Projection For Turkish Hypernym Extraction, Savaş Yildirim
Improving Word Embeddings Projection For Turkish Hypernym Extraction, Savaş Yildirim
Turkish Journal of Electrical Engineering and Computer Sciences
Corpus-driven approaches can automatically explore is-a relations between the word pairs from corpus. This problem is also called hypernym extraction. Formerly, lexico-syntactic patterns have been used to solve hypernym relations. The language-specific syntactic rules have been manually crafted to build the patterns. On the other hand, recent studies have applied distributional approaches to word semantics. They extracted the semantic relations relying on the idea that similar words share similar contexts. Former distributional approaches have applied one-hot bag-of-word (BOW) encoding. The dimensionality problem of BOW has been solved by various neural network approaches, which represent words in very short and dense …
Diversity Of Biochemical Content In Fruits Of Some Indigenous Mulberry Genotypes, Aytül Balik, Mustafa Kenan Geçer, Rafet Aslantaş
Diversity Of Biochemical Content In Fruits Of Some Indigenous Mulberry Genotypes, Aytül Balik, Mustafa Kenan Geçer, Rafet Aslantaş
Turkish Journal of Agriculture and Forestry
This research was carried out to assess the biochemical diversity of the fruits of mulberry genotypes grown in Muş Province in the eastern Anatolia region and to determine the genotypes available for breeding. Morphological and biochemical characteristics of 13 mulberry fruit genotypes, including 5 white (Morus alba) and 8 black (Morus nigra), were determined. Fruit antioxidant capacity was determined by Trolox equivalent antioxidant capacity assay. Fruit weight, pH, soluble solid content, titratable acidity, vitamin C, and antioxidant capacity were 1.38-3.77 g, 4.77-6.79, 14.33%-23.50%, 0.53%-2.20%, 4.47-35.83 mg 100 g-1, and 4.33-13.63 µmol Trolox equivalent g, respectively, indicating enough diversity among genotypes …
Improvement Of The In Vitro Regeneration And Agrobacterium-Mediated Genetic Transformation Of Medicago Sativa L., Farzad Nofouzi, Muhammet Çağri Oğuz, Saber Delpasand Khabbazi, Ali̇ Ergül
Improvement Of The In Vitro Regeneration And Agrobacterium-Mediated Genetic Transformation Of Medicago Sativa L., Farzad Nofouzi, Muhammet Çağri Oğuz, Saber Delpasand Khabbazi, Ali̇ Ergül
Turkish Journal of Agriculture and Forestry
Alfalfa is a fodder crop that accounts for one of the best sources of protein and is widely cultivated around the world. In vitro regeneration of alfalfa has been studied earlier; however, most of the studies were almost intervened with callus formation. In this study, 3 explant sources (cotyledonary node, hypocotyl, and root crown) of two Turkish cultivars (Nimet and Savaş) were excised from young seedlings. Explants were subjected to different concentrations of BAP, BAP-IBA, and TDZ to evaluate the direct in vitro regeneration potential of selected plant parts. Moreover, we transformed the alfalfa plant with pBin19 harboring 35s.GUS-INT_35s.nptII construct …
Effects Of Different Zinc Levels On Grain Yield And Some Phenological Characteristics Of Red Lentil (Lens Culinaris Medic.) Under Arid Conditions, Ayşe Gülgün Öktem
Effects Of Different Zinc Levels On Grain Yield And Some Phenological Characteristics Of Red Lentil (Lens Culinaris Medic.) Under Arid Conditions, Ayşe Gülgün Öktem
Turkish Journal of Agriculture and Forestry
This research aimed to determine the effects of different zinc (Zn) levels on the grain yield and some phenological characteristics of the Fırat-87 red lentil variety (Lens culinaris Medic.). The study was conducted during the winter months of 2013-2014 and 2014- 2015 in Zn-deficit areas of Şanlıurfa, Turkey. The experimental design was a randomized complete block design with 4 replicates. The Fırat-87 lentil variety and Zn sulfate (ZnSO4.7H2O) were used as the plant material and Zn source, respectively. The Zn levels used were the control (0 kg ha-1 Zn), 5 kg ha-1 Zn, 10 kg ha-1 Zn, 15 kg ha-1 …
Using Smoke Solutions In Grass Pea (Lathyrus Sativus L.) To Improve Germination And Seedling Growth And Reduce Toxic Compound Odap, Uğur Başaran, Medi̇ne Çopur Doğrusöz, Erdem Gülümser, Hani̇fe Mut
Using Smoke Solutions In Grass Pea (Lathyrus Sativus L.) To Improve Germination And Seedling Growth And Reduce Toxic Compound Odap, Uğur Başaran, Medi̇ne Çopur Doğrusöz, Erdem Gülümser, Hani̇fe Mut
Turkish Journal of Agriculture and Forestry
The effects of smoke solutions derived from wheat straw on the germination, seedling growth characteristics, and biochemical content of grass pea (Lathyrus sativus L.) were examined in this study. The smoke solutions were applied to petri and pot media at different concentrations. Both experiments were conducted in a randomized plot design with 3 replications. In the pot experiments, the smoke solutions were applied through the initial irrigation at 5 different concentrations (1%, 5%, 10%, 20%, and 40%) while 6 concentrations were used for petri experiments (0.5%, 1%, 2%, 4%, 8%, 10%) and results were compared to a control (distilled water). …
The Application Of Hemp (Cannabis Sativa L.) For A Green Economy: A Review, Tahseen Karche, Manager Rajdeo Singh
The Application Of Hemp (Cannabis Sativa L.) For A Green Economy: A Review, Tahseen Karche, Manager Rajdeo Singh
Turkish Journal of Botany
The concern for the issues related to the growing needs of human civilization like resource depletion, pollution, climate changes, and health risk has led to a search for eco-friendly alternatives to environmental problems. Recently, hemp started gaining popularity for its medicinal, nontoxic, greenhouse negative, and biodegradable properties. Originating from the steppes of Central Asia, Cannabis sativa L. (hemp) is one of the oldest domesticated plants known to humans. Since 5000-4000 BC, different parts of the plant were used for spinning, weaving, papermaking, the seed for human feed, animal feeds, medicinal, and health purposes. Reports also suggest the use of hemp …
Word Sense Disambiguation Using Semantic Kernels With Class-Based Term Values, Ayşe Berna Altinel, Murat Can Gani̇z, Bi̇lge Şi̇pal, Eren Can Erkaya, Onur Can Yücedağ, Muhammed Ali̇ Doğan
Word Sense Disambiguation Using Semantic Kernels With Class-Based Term Values, Ayşe Berna Altinel, Murat Can Gani̇z, Bi̇lge Şi̇pal, Eren Can Erkaya, Onur Can Yücedağ, Muhammed Ali̇ Doğan
Turkish Journal of Electrical Engineering and Computer Sciences
In this study, we propose several semantic kernels for word sense disambiguation (WSD). Our approaches adapt the intuition that class-based term values help in resolving ambiguity of polysemous words in WSD. We evaluate our proposed approaches with experiments, utilizing various sizes of training sets of disambiguated corpora (SensEval). With these experiments we try to answer the following questions: 1.) Do our semantic kernel formulations yield higher classification performance than traditional linear kernel?, 2.) Under which conditions a kernel design performs better than others?, 3.) Does the addition of class labels into standard term-document matrix improve the classification accuracy?, 4.) Is …
Primary Report Of First Documentation Of Mammal Footprints From The Late Oligocene Inthe Sivas Basin, Turkey, Beki̇r Levent Mesci̇, Ahmet Cem Erkman, Şaki̇r Önder Özkurt
Primary Report Of First Documentation Of Mammal Footprints From The Late Oligocene Inthe Sivas Basin, Turkey, Beki̇r Levent Mesci̇, Ahmet Cem Erkman, Şaki̇r Önder Özkurt
Turkish Journal of Earth Sciences
The footprints in this study, which were considered to have been made by ungulates, were discovered on mudstone that was approximately 5 cm thick, near an abundant mud-cracked plane located on the stratigraphic subsurface of the late Oligocene Karayün Formation, which crops out over wide areas in southern Sivas (Turkey) and has terrestrial, fluvial sediment characteristics. These ungulate footprints documented from the late Oligocene of the Karayün Formation in southern Sivas represent the first reported vertebrates in Anatolia. The footprints of three different species of ungulates were identified. The shapes, depth, and widths of the footprints provided some basic ichnotaxonomic …
Analyzing The Effect Of Laparoscopy Duration Time On Peroperative Gastroesophageal Reflux, Gökhan Berktuğ Bahadir, Hakan Taşkinlar, Caner İsbi̇r, İsa Killi, Di̇lek Yünlüel, Ülkü Çömelekoğlu, Ali̇ Nayci
Analyzing The Effect Of Laparoscopy Duration Time On Peroperative Gastroesophageal Reflux, Gökhan Berktuğ Bahadir, Hakan Taşkinlar, Caner İsbi̇r, İsa Killi, Di̇lek Yünlüel, Ülkü Çömelekoğlu, Ali̇ Nayci
Turkish Journal of Medical Sciences
Background/aim: Intraabdominal pressure (IAP) is one of the main reasons for gastroesophageal reflux (GER). This study investigates whether IAP during laparoscopic surgery leads to GER in a time-dependent manner.Materials and methods: In a laparoscopy model, 15 mmHg IAP was created in 8 Wistar albino rats in the Trendelenburg position (TP). A 5 mm laparotomy was performed in the left lower abdominal region, and a 6 Fr catheter was placed intraabdominally. Air was insufflated into the abdominal cavity, and the pressure was kept constant at 15 mmHg. Esophageal pH alterations were measured by pH sticks for 4 h every 30 min.Results: …
A Pilot Study On The Beneficial Effects Of Additional Selenium Supplementation To Methimazole For Treating Patients With Graves' Disease, Bin Xu, Di Wu, Hong Ying, Ying Zhang
A Pilot Study On The Beneficial Effects Of Additional Selenium Supplementation To Methimazole For Treating Patients With Graves' Disease, Bin Xu, Di Wu, Hong Ying, Ying Zhang
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to assess the effect of a combination use of methimazole (MMI) and selenium (Se) in the treatment of Graves' disease (GD). Materials and methods: A total of 103 newly diagnosed hyperthyroidism patients were randomized to MMI and MMI + Se combination groups. After treatment for 6 months, the levels of triiodothyronine (FT3), free thyroxine (FT4), thyrotropin receptor antibody (TRAb), thyroid peroxidase antibody (TPOAb), and thyroglobulin antibody (TGAb) were observed. An in vitro culture model of thyroid cells was established and the protein expression and mRNA levels of TRAb, TPOAb, and TGAb were determined …
Can Apelin Play A Role In The Etiology Of Tinnitus?, Nuray Ensari̇, Özer Erdem Gür, Ni̇lgün Gür, Ömer Tarik Selçuk, Levent Renda, Mustafa Deni̇z Yilmaz, Mehmet Türker Öztürk, Yeşi̇m Çeki̇n
Can Apelin Play A Role In The Etiology Of Tinnitus?, Nuray Ensari̇, Özer Erdem Gür, Ni̇lgün Gür, Ömer Tarik Selçuk, Levent Renda, Mustafa Deni̇z Yilmaz, Mehmet Türker Öztürk, Yeşi̇m Çeki̇n
Turkish Journal of Medical Sciences
Background/aim: Tinnitus is seen in 15% of the general population; in 1%-6% of this number, the quality of life is seriously affected by this chronic condition. Chemical, oxidative, and emotional stressors are important in terms of the clinical course of tinnitus. Apelin is an endogenous peptide which is an oxidative stress mediator. It has been shown that the apelin/APJ (apelin junction receptor) system plays various roles in the physiology and pathophysiology of many organs. However, the role of the apelin/APJ system as an oxidative stress mediator in tinnitus is unknown. We investigated the level of apelin in patients with normal …
Evaluation Of Being Overweight/Obese And Related Sociodemographic Factors In 0-5 Year Age Group In Turkey: Turkey Demographic Health Survey 2013 Advanced Analysis, Asi̇ye Uğraş Di̇kmen, Hande Konşuk Ünlü, Lütfi̇ye Hi̇lal Özcebe
Evaluation Of Being Overweight/Obese And Related Sociodemographic Factors In 0-5 Year Age Group In Turkey: Turkey Demographic Health Survey 2013 Advanced Analysis, Asi̇ye Uğraş Di̇kmen, Hande Konşuk Ünlü, Lütfi̇ye Hi̇lal Özcebe
Turkish Journal of Medical Sciences
Background/aim: To determine risk factors of overweightness/obesity in children aged 0-5 years in the Turkish population.Materials and methods: We made advanced analysis using the Turkey Demographic Health Survey (TDHS) 2013 female database, in which data from children aged under five years and their mothers are included. Analyses were performed using weight for height index data. The children were divided into two groups by age as 0-23 months and 24-59 months.Results: The analysis comprised 2196 children aged under 5 years. Several factors were associated with an increase in overweightness/obesity of children aged under 5 years. Overweight/obesity in children aged 0-23 months …
Effect Of 4 Weeks Of Frankincense Consumption On Explicit Motor Memory And Serum Bdnf In Elderly Men, Elham Asadi, Mohammad Reza Shahabi Kaseb, Rasool Zeidabadi, Mohammad Reza Hamedinia
Effect Of 4 Weeks Of Frankincense Consumption On Explicit Motor Memory And Serum Bdnf In Elderly Men, Elham Asadi, Mohammad Reza Shahabi Kaseb, Rasool Zeidabadi, Mohammad Reza Hamedinia
Turkish Journal of Medical Sciences
Background/aim: Memory is a mechanism for coding, storing, and recalling information. Weak memory and learning disability are common psychological problems in the elderly. The aim of this study was to investigate the effect of 4 weeks of frankincense consumption on explicit motor memory and serum BDNF in the elderly.Materials and methods: Twenty elderly men (mean age of 60.2 ± 1.7 years) were randomly divided into two groups: experimental (n = 12) and placebo (n = 8). The first blood samples were collected 24 h before the pretest. Then both groups participated in a 4-week exercise program based on the protocol …
Development Of Antimicrobial Gelatin Films With Boron Derivatives, Sanem Argin, Merve Güleri̇m, Fi̇kretti̇n Şahi̇n
Development Of Antimicrobial Gelatin Films With Boron Derivatives, Sanem Argin, Merve Güleri̇m, Fi̇kretti̇n Şahi̇n
Turkish Journal of Biology
Food packaging technology has been advancing to provide safe and high quality food products and to minimize food waste. Moreover, there is a dire need to replace plastic materials in order to reduce environmental pollution. The aim of this study was to prepare biodegradable antimicrobial packaging films from gelatin. Boric acid, disodium octaborate tetrahydrate, and sodium pentaborate were incorporated as the antimicrobial agents. Films containing boric acid and its salts showed antibacterial effect against Staphylococcus aureus and Pseudomonas aeruginosa, as well as antifungal and anticandidal effects against Aspergillus niger and Candida albicans. The mechanical strength of the films was mostly …
Prediction And Expression Analysis Of G Protein-Coupled Receptors In The Laboratory Stick Insect, Carausius Morosus, Burçi̇n Duan Şahbaz, Necla Bi̇rgül İyi̇son
Prediction And Expression Analysis Of G Protein-Coupled Receptors In The Laboratory Stick Insect, Carausius Morosus, Burçi̇n Duan Şahbaz, Necla Bi̇rgül İyi̇son
Turkish Journal of Biology
G protein-coupled receptors (GPCRs) are 7-transmembrane proteins that transduce various extracellular signals into intracellular pathways. They are the major target of neuropeptides, which regulate the development, feeding behavior, mating behavior, circadian rhythm, and many other physiological functions of insects. In the present study, we performed RNA sequencing and de novo transcriptome assembly to uncover the GPCRs expressed in the stick insect Carausius morosus. The transcript assemblies were predicted for the presence of 7-transmembrane GPCR domains. As a result, 430 putative GPCR transcripts were obtained and 43 of these revealed full-length sequences with highly significant similarity to known GPCR sequences in …
Characterization Of Mesenchymal Stem Cells In Mucolipidosis Type Ii (I-Cell Disease), Sevi̇l Köse, Fati̇ma Aerts Kaya, Bülent Bariş Kuşkonmaz, Fahri̇ye Duygu Çeti̇nkaya
Characterization Of Mesenchymal Stem Cells In Mucolipidosis Type Ii (I-Cell Disease), Sevi̇l Köse, Fati̇ma Aerts Kaya, Bülent Bariş Kuşkonmaz, Fahri̇ye Duygu Çeti̇nkaya
Turkish Journal of Biology
Mucolipidosis type II (ML-II, I-cell disease) is a fatal inherited lysosomal storage disease caused by a deficiency of the enzyme N-acetylglucosamine-1-phosphotransferase. A characteristic skeletal phenotype is one of the many clinical manifestations of ML-II. Since the mechanisms underlying these skeletal defects in ML-II are not completely understood, we hypothesized that a defect in osteogenic differentiation of ML-II bone marrow mesenchymal stem cells (BM-MSCs) might be responsible for this skeletal phenotype. Here, we assessed and characterized the cellular phenotype of BM-MSCs from a ML-II patient before (BBMT) and after BM transplantation (ABMT), and we compared the results with BM-MSCs from a …