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Full-Text Articles in Entire DC Network
Does The Volume Overload Exaggerate The Severity Of Mitral Regurgitation In Patients With Decompensated Heart Failure?, Göktuğ Savaş, Ömer Şahi̇n, Mustafa Yaşan, Uğur Karabiyik, Ni̇hat Kalay, Ali̇ Doğan, Ferhan Elmali, Abdurrahman Oğuzhan
Does The Volume Overload Exaggerate The Severity Of Mitral Regurgitation In Patients With Decompensated Heart Failure?, Göktuğ Savaş, Ömer Şahi̇n, Mustafa Yaşan, Uğur Karabiyik, Ni̇hat Kalay, Ali̇ Doğan, Ferhan Elmali, Abdurrahman Oğuzhan
Turkish Journal of Medical Sciences
Background/aim: Diagnosing and managing functional mitral regurgitation (MR) is often challenging and requires an integrated approach including a comprehensive echocardiographic examination. However, the effects of volume overload on the echocardiographic assessment of MR severity are uncertain. The purpose of this study was to weigh the effects of volume overload in the echocardiographic assessment of MR severity among patients with heart failure (HF). Materials and methods: Twenty-nine patients with decompensated HF, who had moderate or severe MR, were included in the present study. The volume status and the N-terminal pro-B-type natriuretic peptide (proBNP) levels were recorded and the echocardiographic parameters were …
Effects Of Acute Hypoxia On Auditory Pathway Of Wistar Albino Rats, Nevreste Di̇dem Sonbay Yilmaz, Cem Saka, Si̇bel Ali̇cura Tokgöz, Murat Çalişkan, Erkan Vuralkan, Ömer Beşalti
Effects Of Acute Hypoxia On Auditory Pathway Of Wistar Albino Rats, Nevreste Di̇dem Sonbay Yilmaz, Cem Saka, Si̇bel Ali̇cura Tokgöz, Murat Çalişkan, Erkan Vuralkan, Ömer Beşalti
Turkish Journal of Medical Sciences
Background/aim: Ischemia is insufficient blood flow to provide adequate oxygenation. In the present study, we aimed to show whether acute hypoxia has a critical oxygen value that may lead to the deterioration of cochlear function. Materials and methods: Under general anesthesia, prehypoxic signal-to-noise ratios were determined by distortion product otoacoustic emissions (DPOAE). The oxygen saturation (SaO2) values of rats were monitored with an oxygen saturation probe. Rats were injected with an extra dose of anesthetic agent, and SaO2 was reduced. DPOAE values in SaO2 100?90, 90?80, 80?70, and 70?60 posthypoxic values were measured and compared statistically with prehypoxic values. Results: …
Anakinra, An Interleukin-1 Receptor Antagonist, Increases The Morphine Analgesic Effectand Decreases Morphine Tolerance Development By Modulating Oxidative Stress Andendoplasmic Reticulum Stress In Rats, Onur Avci, Ahmet Şevki̇ Taşkiran
Anakinra, An Interleukin-1 Receptor Antagonist, Increases The Morphine Analgesic Effectand Decreases Morphine Tolerance Development By Modulating Oxidative Stress Andendoplasmic Reticulum Stress In Rats, Onur Avci, Ahmet Şevki̇ Taşkiran
Turkish Journal of Medical Sciences
Background/aim: Recent studies have shown that inflammation plays a role in morphine analgesia and tolerance development. Anakinra is a competitive inhibitor of IL-1 receptors and an antiinflammatory protein regulating IL-1ß's biological activity by avoiding signal transduction. In this study, we aimed to examine the effects of anakinra on morphine analgesia and tolerance. Materials and methods: In this study, 36 Wistar Albino (230-250 g) male rats were used. Animals were divided into 6 groups: saline (S), 100 mg/kg anakinra (A), 5mg/kg morphine (M), M+A, morphine tolerance (MT), and MT+A. The resulting analgesic effect was measured with hot plate and tail-flick analgesia …
Antiviral Treatment Of Covid-19, Serap Yavuz, Serhat Ünal
Antiviral Treatment Of Covid-19, Serap Yavuz, Serhat Ünal
Turkish Journal of Medical Sciences
Currently, there is not any specific effective antiviral treatment for COVID-19. Although most of the COVID-19 patients have mild or moderate courses, up to 5%-10% can have severe, potentially life threatening course, there is an urgent need for effective drugs. Optimized supportive care remains the mainstay of therapy. There have been more than 300 clinical trials going on, various antiviral and immunomodulating agents are in various stages of evaluation for COVID-19 in those trials and some of them will be published in the next couple of months. Despite the urgent need to find an effective antiviral treatment for COVID-19 through …
Immune Gene Therapy Of Cancer, Hakan Akbulut
Immune Gene Therapy Of Cancer, Hakan Akbulut
Turkish Journal of Medical Sciences
Cancer gene therapy emerged as a promising treatment modality 3 decades ago. However, the failure of the first gene therapy trials in cancer treatment has decreased its popularity. Likewise, immunotherapy has followed a similar course. While it was a popular and promising treatment with IL-2 and interferon and cancer vaccines in the 1980s, it later lost its popularity. Immunotherapy became one of the main options for cancer treatment with the successful use of immune checkpoint inhibitors in clinics approximately 10 years ago. The success of immunotherapy has increased even more with the introduction of cancer gene therapy methods in this …
A Review On Ethnobotany And Promising Pharmacological Aspects Of An Endangered Medicinal Plant, Curcuma Caesia Roxb., Angana Borah, Deepak Kumar, Manabi Paw, Twahira Begum, Mohan Lal
A Review On Ethnobotany And Promising Pharmacological Aspects Of An Endangered Medicinal Plant, Curcuma Caesia Roxb., Angana Borah, Deepak Kumar, Manabi Paw, Twahira Begum, Mohan Lal
Turkish Journal of Botany
Curcuma caesia Roxb. is one of the rarest medicinal plants used traditionally for the mitigation of various ailments. It is now classified as an endangered species and through this review, an overview regarding the pharmacological benefits of this plant has been put forward. Information on the ethnobotany and phytochemistry along with pharmacological activities was retrieved from the electronic databases for the period from 1962 to 2019. A literature review of articles published in local magazines, conference papers, unpublished materials, and books on traditional and medicinal plants of India was also conducted. There is very little information on C.caesiais in the …
Aeropalynological Survey In The City Center Of Aydın (Turkey), Aykut Güvensen, Ulaş Uğuz, Tarik Altun, Ayli̇n Eşi̇z Dereboylu, Nedret Şengonca Tort
Aeropalynological Survey In The City Center Of Aydın (Turkey), Aykut Güvensen, Ulaş Uğuz, Tarik Altun, Ayli̇n Eşi̇z Dereboylu, Nedret Şengonca Tort
Turkish Journal of Botany
Airborne pollen grains in Aydın, an important city for agriculture and tourism in the western part of Turkey, were studied for 2 years (2014 and 2015) using the volumetric method. During a 2-year study conducted in the city center, an average of 19,226 pollen grains belonging to 46 taxa were detected. Among these detected taxa, 29 (average 73.97%) belonged to arboreal plants and 17 (average 24.95%) to nonarboreal plants. The highest pollen concentrations belonged to Olea europaea (21.02%), Quercus (15.23%), Poaceae (11.89%), Pinaceae (11.47%), Cupressaceae/Taxaceae (11.11%), Platanus(4.12%), Morus (3.83%), and Urticaceae (3.58%), which were considered to be the dominant species. …
Stress Response Related To Ultrasonographic Examination In Dogs, Cenker Çağri Cingi, Abdurrahman Fati̇h Fi̇dan, Durmuş Fati̇h Başer, Mehmet Uçar, Zülfükar Kadi̇r Saritaş
Stress Response Related To Ultrasonographic Examination In Dogs, Cenker Çağri Cingi, Abdurrahman Fati̇h Fi̇dan, Durmuş Fati̇h Başer, Mehmet Uçar, Zülfükar Kadi̇r Saritaş
Turkish Journal of Veterinary & Animal Sciences
This study investigated whether abdominal ultrasonography, a frequently used examination method in clinics and hospitals, causes stress in dogs. For the study, 10 healthy dogs were used. Following general examination, intravenous catheters were placed in the V. cephalica accecorius of the dogs and blood specimens were collected to obtain serum and plasma samples (minute 0). After a 30- min break, ultrasonography was applied following shaving of the abdominal region. Serum and plasma samples were collected from the intravenous catheters at the 5th, 15th, and 20th minutes of the ultrasonographic examination during which the urinary bladder, left kidney, spleen, stomach, liver, …
Estimation Of Genetic Parameters For Weaning Weight Of Awassi Lambs By Using Classical And Bayesian Methods, Adi̇le Tatliyer, Si̇nan Baş
Estimation Of Genetic Parameters For Weaning Weight Of Awassi Lambs By Using Classical And Bayesian Methods, Adi̇le Tatliyer, Si̇nan Baş
Turkish Journal of Veterinary & Animal Sciences
The aim of this study was to estimate variance components and genetic parameters with six different animal models and two approaches (Bayesian and classical) on weaning weight (WW) of Awassi lambs. For this purpose, the data were obtained from Sheep and Goat Breeders' Associations of Osmaniye in Turkey. The data of 4971 progenies (from 80 rams and 1917 ewes) born between 2012 and 2016 raised under traditional conditions were evaluated. Year/season, sex, birth type, dam age, and flock size were fixed effects. All these effects except birth type were found statistically significant (P < 0.01). The overall least squares mean of weaning weight (WW) was obtained as 17.93 ± 0.05 kg. Variance components and genetic parameters were estimated by MCMC algorithms with R (for Bayesian approach) and by REML procedure with MTDFREML (for classical approach) programs. The Akaike information criterion (AIC), the log likelihood function (-2logL), and deviance information criterion (DIC) values were taken as criteria to choose the best model. Direct heritabilities of WW ranged from 0.20 to 0.35 across the models. The genetic correlation between additive genetic effect and maternal effect ranged from 0.00 to 1.00. The results were found similar across methodologies and maternal additive genetic variance resulted in lower than direct additive genetic variance. According to this study, both approaches are suitable for estimation of genetic parameters in the case of low sample size. However, the Bayesian approach, becoming increasingly popular, may be feasible to estimate variancecovariance components and genetic parameters.
Cranial Size And Shape Sexual Dimorphism In The Kangal Dog From Turkey, Pere Miquel Parés-Casanova, Abu Bakar Siddiq, Vedat Onar
Cranial Size And Shape Sexual Dimorphism In The Kangal Dog From Turkey, Pere Miquel Parés-Casanova, Abu Bakar Siddiq, Vedat Onar
Turkish Journal of Veterinary & Animal Sciences
This study has so far been the first attempt to characterize and quantify skull sexual variation in Kangal dog, by means of geometric morphometric techniques. A sample of 16 adult Kangal crania has been analyzed with this purpose. To obtain a full image of morphological pattern, digital pictures were taken from the ventral, left lateral, and dorsal sides of each skull, and a total of 16, 15, and 16 landmarks respectively were obtained on each image. Skull size and shape differed significantly in all aspects among different sexes, male skulls being bigger. Shape differences were observed mainly on zygomatic arch …
The Effects Of Different Doses Of Diclofenac Sodium On Newborn Rat Hippocampus Exposed During The Third Trimester, Ebru Eli̇bol, Süleyman Kaplan, Gamze Altun, Abdurrahman Aksoy, Berri̇n Zuhal Altunkaynak
The Effects Of Different Doses Of Diclofenac Sodium On Newborn Rat Hippocampus Exposed During The Third Trimester, Ebru Eli̇bol, Süleyman Kaplan, Gamze Altun, Abdurrahman Aksoy, Berri̇n Zuhal Altunkaynak
Turkish Journal of Veterinary & Animal Sciences
The main aim of the present study was to examine the neurotoxic effects of prenatal exposure to varying doses of diclofenac sodium (DS) on the rat hippocampus. Twenty-eight Wistar albino adult female rats weighing 280-300 g were initially used for pregnancy. When vaginal plaques were seen in female rats, it was accepted as the 0th day of pregnancy. Female rats were divided into five main groups; pure control, saline, low dose DS (3.6 mg/kg), moderate dose DS (9 mg/kg), and high dose DS (18 mg/kg). They were exposed to these treatments during their gestation. After birth, all newborn male rats …
Effect Of Transportation Distance And Crating Density On Preslaughter Losses And Blood Biochemical Profile In Broilers During Hot And Humid Weather, Faisal Hussnain, Athar Mahmud, Shahid Mahmood, Muhammad Hayat Jaspal
Effect Of Transportation Distance And Crating Density On Preslaughter Losses And Blood Biochemical Profile In Broilers During Hot And Humid Weather, Faisal Hussnain, Athar Mahmud, Shahid Mahmood, Muhammad Hayat Jaspal
Turkish Journal of Veterinary & Animal Sciences
Transportation of broilers from different localities to the processing plants is a critical step in the farm to fork chain, and any disturbance in this chain may result in worst consequences. Keeping this scenario in view, a study was conducted to determine the live losses at different transportation distances (~80, 160, 240 km) and crating densities (10, 12, 15 birds/crate) during hot and humid summer. The uniform weight birds were picked from a farm and placed in plastic crates (0.91 m × 0.55 m). The results showed a significant increase in body weight loss and dead on arrival (%) with …
Evaluation Of Cytotoxic, Apoptotic Effects And Phenolic Compounds Of Sea Cucumberholothuria Tubulosa (Gmelin, 1791) Extracts, Mehli̇ka Alper, Melek Güneş
Evaluation Of Cytotoxic, Apoptotic Effects And Phenolic Compounds Of Sea Cucumberholothuria Tubulosa (Gmelin, 1791) Extracts, Mehli̇ka Alper, Melek Güneş
Turkish Journal of Veterinary & Animal Sciences
This study aimed to investigate the potential cytotoxic effects and phenolic contents of aqueous (HTS) and methanolic (HTM) extracts of Holothuria tubulosa gathered from Muğla (Turkey) against different cancer cells for the first time. An MTT assay was carried out to determine cellular viability. Apoptotic cell death was determined using flow cytometry. DNA fragmentation assay and caspase-3 activity analysis were carried out. Both extracts were analyzed by high performance liquid chromatography (HPLC) for quantification of phenolic compounds. Both HTS and HTM extracts generally caused a decrease in the cell viability in a concentration- and timedependent manner. The lowest IC$_{50}$ value …
Gastrointestinal Helminths Detected In Wild Horses In Konya Province, Turkey, Onur Ceylan, Bi̇lal Di̇k, Ceylan Ceylan, Asma Semassel, Özlem Deri̇nbay Eki̇ci̇, Gonca Sönmez
Gastrointestinal Helminths Detected In Wild Horses In Konya Province, Turkey, Onur Ceylan, Bi̇lal Di̇k, Ceylan Ceylan, Asma Semassel, Özlem Deri̇nbay Eki̇ci̇, Gonca Sönmez
Turkish Journal of Veterinary & Animal Sciences
This study was conducted to identify the gastrointestinal helminths of wild horses in Konya, Turkey. Fresh stool samples collected from 66 horses were evaluated by flotation, sedimentation, Baermann-Wetzel, and stool culture methods. All 66 stool samples examined were found to be positive for helminths and the following parasites were detected: Trichonema spp. was detected in all stool samples (100%), followed by Poteriostomum spp. (45.5%), Strongylus vulgaris (34.9%), and Strongylus equinus (27.3%). In addition, Oesophagodontus spp. (9.1%), Strongylus edentatus (7.6%), Triodontophorus spp. (4.6%), Gyalocephalus spp. (4.6%), Oxyuris equi (3.0%), Parascaris equorum (1.5%), and Strongyloides westeri (1.5%) were detected at lower levels. …
Assessment Of Mitogen-Activated Protein Kinases As Therapeutic Targets For The Treatmentof Babesiosis And Theileriosis, Özal Mutlu
Turkish Journal of Veterinary & Animal Sciences
The Piroplasmida order comprises parasitic protozoa including the Theileria and Babesia species that are transmitted by vector ticks and can cause severe diseases in domestic and wild animals. Because of limited therapies and available drug resistance, the discovery of new, effective, and safer drugs for veterinary use is important. Mitogen-activated protein kinases (MAPK) are a group of serine-threonine protein kinases found in diverse species, including animals and protozoa that conduct vital cellular functions. Therefore, they have been at the centre of drug design studies for many years. Computer-aided structure-based drug design is a fast and effective way in drug discovery …
Comparative Morphological Analysis Of Diploid And Triploid Oysters, Crassostrea Gigas,Farmed In The Black Sea, Oksana Yurievna Vialova
Comparative Morphological Analysis Of Diploid And Triploid Oysters, Crassostrea Gigas,Farmed In The Black Sea, Oksana Yurievna Vialova
Turkish Journal of Veterinary & Animal Sciences
Triploid organisms, in particular oysters, are widely used in marine aquaculture. However, the advantage of triploid oysters compared to diploids has not been proven in all cases. Comparative morphological analysis of Pacific oysters Crassostrea gigas of different ploidy levels allows evaluating the benefits of raising triploids in the Black Sea. First, the morphological characteristics of diploid and triploid Pacific oysters C. gigas farmed in the Black Sea were studied. Allometric ratios of weight (W, g) and shell height (H, mm) of oysters were obtained, which are described by the equations W$_{2n}$ = 4 × 10$^{-4}$ × H$_{2n}$ $^{2.56}$, R2 = …
Comparison Of Blup And Bayesian Methods For Different Sizes Of Training Population Ingenomic Selection, Samet Hasan Abaci, Hasan Önder
Comparison Of Blup And Bayesian Methods For Different Sizes Of Training Population Ingenomic Selection, Samet Hasan Abaci, Hasan Önder
Turkish Journal of Veterinary & Animal Sciences
This study aims to compare the accuracy of pedigree-based and genomic-based breeding value prediction for different training population sizes. In this study, Bayes (A, B, C, Cpi) and GBLUP methods for genomic selection and BLUP method for pedigree-based selection were used. Genomic and pedigree-based breeding values were estimated for partial milk yield (158 days) of Holstein cows (400 individuals) from a private enterprise in the USA. For this aim, populations were created for indirect breeding value estimates as training (322-360) and test (78-40) populations. In animals genotyped with a 54k SNP, the marker file was encoded as -10, 0, and …
Effects Of Oregano (Oreganum Onites L.) Aromatic Water On Rumen Microbialfermentation Of Holstein Calves, Serkan Özkaya, Ozan Emre Almali, Yavuz Ayan, Sabri̇ Erbaş, Taylan Aksu
Effects Of Oregano (Oreganum Onites L.) Aromatic Water On Rumen Microbialfermentation Of Holstein Calves, Serkan Özkaya, Ozan Emre Almali, Yavuz Ayan, Sabri̇ Erbaş, Taylan Aksu
Turkish Journal of Veterinary & Animal Sciences
The study aimed to determine the effects of the addition of aromatic oregano water (AOW) on rumen fermentation of Holstein calves. For this purpose, 20 Holstein calves were divided into four groups (n = 5) and fed with three different doses of AOW (1, 1.5, and 2%). The experimental groups were formed as follows; the control group (CNT): milk + starter; G1: 1% AOW supplemented milk + starter; G2: 1.5% AOW supplemented milk + starter; G3: 2% AOW supplemented milk + starter. The rumen fluid was taken from the oesophagus at 60 days of age with the aid of a …
Chemical Compounds And Gas Production Kinetics Of Annual Ryegrass Hay In Distinctnitrogen Levels And Cutting Heights, Juliana Reolon Pereira, Marcela Abbado Neres, Itacir Eloi Sandini, Ana Carolina Fluck, Olmar Antônio Denardin Costa, Laércio Ricardo Sartor
Chemical Compounds And Gas Production Kinetics Of Annual Ryegrass Hay In Distinctnitrogen Levels And Cutting Heights, Juliana Reolon Pereira, Marcela Abbado Neres, Itacir Eloi Sandini, Ana Carolina Fluck, Olmar Antônio Denardin Costa, Laércio Ricardo Sartor
Turkish Journal of Veterinary & Animal Sciences
The aim of our work was to evaluate the chemical composition and cumulative gas production profiles of annual ryegrass hay through in vitro incubations for two cutting heights and different nitrogen fertilization doses. The experimental design was randomized blocks with split-plots. The nitrogen doses (0, 75, 150, and 225 kg N ha$^{-1}$) were distributed in the main plot and the subplots. To make the hay, the annual ryegrass was cut at heights of 5 and 10 cm from the ground, with three replications each. In the experimental area, corn was cropped in the summer and annual ryegrass pasture in the …
Macro- And Micromineral Contents Of Different Quinoa (Chenopodium Quinoa Willd.)Varieties Used As Forage By Cattle, Mustafa Tan
Macro- And Micromineral Contents Of Different Quinoa (Chenopodium Quinoa Willd.)Varieties Used As Forage By Cattle, Mustafa Tan
Turkish Journal of Agriculture and Forestry
Mineral deficiencies or mineral excess affect livestock production in most regions of the world. For this reason, it is important to know the mineral contents of forages used in animal feeding. Quinoa (Chenopodium quinoa Willd.), which has become a popular grain crop around the world in recent years, is used as forage in animal feeding. This study was carried out to determine the contents of macro- and microminerals and mineral balance in 9 different quinoa varieties. The results of the study indicated that mineral contents of forages show great variation between quinoa varieties. The Cherry Vanilla variety is rich in …
Agronomic Traits Of Einkorn And Emmer Under Different Seeding Rates And Topdressingwith Organic Fertilizers, Ana Pospisil, Milan Pospisil, Marina Brcic
Agronomic Traits Of Einkorn And Emmer Under Different Seeding Rates And Topdressingwith Organic Fertilizers, Ana Pospisil, Milan Pospisil, Marina Brcic
Turkish Journal of Agriculture and Forestry
The goal of this research carried out at the experimental facility of the Faculty of Agriculture of the University of Zagreb in 2015/2016, 2016/2017 and 2017/2018 was to determine the influence of seeding rate and topdressing with organic fertilizers on yield and yield components in einkorn (Triticum monococcum subsp. monococcum) and emmer (Triticum dicoccon) populations collected in the Croatian region of Slavonia. The research comprised four seeding rates: 100, 150, 200, and 250 grains per m2; topdressing with organic fertilizers (Fertil Supernova 12.5 N and Ilsamin N90); and a control (no topdressing). Einkorn populations achieved a higher yield of hulled …
Dna Fingerprinting And Genetic Diversity Analysis Of World Quinoa Germplasm Usingipbs-Retrotransposon Marker System, Muzaffer Barut, Muhammad Azhar Nadeem, Tolga Karaköy, Faheem Shahzad Baloch
Dna Fingerprinting And Genetic Diversity Analysis Of World Quinoa Germplasm Usingipbs-Retrotransposon Marker System, Muzaffer Barut, Muhammad Azhar Nadeem, Tolga Karaköy, Faheem Shahzad Baloch
Turkish Journal of Agriculture and Forestry
Quinoa is an important staple food crop for millions of impoverished rural inhabitants of the Andean region. Quinoa is considered a good source of protein,vitamins, minerals, and antioxidants. This study aimed to investigate the genetic diversity and population structure of world quinoa germplasm originating from 8 countries through the iPBS-retrotransposon marker system. Molecular characterization was performed using the 11 most polymorphic primers. A total of 235 bands were recorded, of which 66.8% were polymorphic. Mean polymorphism information content (PIC) was 0.410. Various diversity indices including mean effective number of alleles (1.269), mean Shannon's information index (0.160) and gene diversity (0.247) …
Dihydroquercetin Increases The Adaptive Potential Of Wild Soybean Against Copper Sulfateand Cadmium Sulfate Toxicity, Darya Konstantinovna Chernyshuk, Lubov Yegorovna Ivachenko, Hülya Doğan, Ghulam Raza, Muhammad Amjad Ali, Kirill Sergeyevich Golokhvast, Muhammad Amjad Nawaz
Dihydroquercetin Increases The Adaptive Potential Of Wild Soybean Against Copper Sulfateand Cadmium Sulfate Toxicity, Darya Konstantinovna Chernyshuk, Lubov Yegorovna Ivachenko, Hülya Doğan, Ghulam Raza, Muhammad Amjad Ali, Kirill Sergeyevich Golokhvast, Muhammad Amjad Nawaz
Turkish Journal of Agriculture and Forestry
In this study, the mechanism of the biochemical adaptation of wild soybean to the experimentally modeled effects of cadmium sulfate and copper sulfate in approximately double permissible concentration was investigated. The extracted concentrations of cadmium and copper in the experimental soil were determined by inversion voltammetry - 1.46 and 48.25 mg/kg, respectively. Growing soybeans in soil with the addition of copper and cadmium sulfates led to an increase in the concentration of malonic dialdehyde in soybean seeds relative to control by 62% and 38%, respectively, which confirmed the strengthening of oxidative processes. There was also an increase in the specific …
Determination Of The Chemical Composition Of Seeds, Peels, And Seedcakes From Two Genotypes Of Cape Gooseberry (Physalis Peruviana L.), Venelina Popova, Zhana Petkova, Tanya Ivanova, Magdalena Stoyanova, Nikolay Panayotov, Nadezhda Mazova, Albena Stoyanova
Determination Of The Chemical Composition Of Seeds, Peels, And Seedcakes From Two Genotypes Of Cape Gooseberry (Physalis Peruviana L.), Venelina Popova, Zhana Petkova, Tanya Ivanova, Magdalena Stoyanova, Nikolay Panayotov, Nadezhda Mazova, Albena Stoyanova
Turkish Journal of Agriculture and Forestry
Physalis peruviana L. fruit (Cape gooseberry, CG) is a rich source of phytonutrients, including vitamins, minerals, polyphenols, polyunsaturated fatty acids (FAs), phytosterols, dietetic fibers, and others. The popularity and production areas of CG have been expanding worldwide, thus producing fruit with origin-substantiated differences in their nutrient composition.This study was based on the comparative assessment of 2 genotypes of CG produced in Bulgaria (CG-P and CG-F), through analysis of the lipid fraction of different fruit elements (seeds, peels), and further examination of the extracted seedcakes. The CG seeds reasonably yielded more oil (17.0%-22.2%) than the isolated peels (2.8%-2.9%). The main FAs …
Evolutionary Analyses Of Phylum Chaetognatha Based On Mitochondrial Cytochromeoxidase I Gene, Sam Peter, Manojkumar Bhaskaran Nair, Devika Pillai
Evolutionary Analyses Of Phylum Chaetognatha Based On Mitochondrial Cytochromeoxidase I Gene, Sam Peter, Manojkumar Bhaskaran Nair, Devika Pillai
Turkish Journal of Zoology
Chaetognaths (arrow worms) are an enigmatic group of transparent planktonic invertebrates and play an important role in the marine food web. Their morphological and developmental features have raised extensive debates since the discovery of the phylum in the 18th century. Uncertainty in the phylogenetic placement of certain chaetognath species still exists and is puzzling many scientists who have tried to clarify this task. Studies using a portion of both small subunit ribosomal ribonucleic acid (SSU rRNA) and large subunit ribosomal ribonucleic acid (LSU rRNA) genes when integrated with conventional taxonomy were contributed to resolve taxonomical issues in this group. Here …
The Occurrence Of Xanthochroism In The Thinlip Grey Mullet, Chelon Ramada(Teleostei: Mugilidae), From The Aegean Sea, Sencer Akalin, Zafer Tosunoğlu
The Occurrence Of Xanthochroism In The Thinlip Grey Mullet, Chelon Ramada(Teleostei: Mugilidae), From The Aegean Sea, Sencer Akalin, Zafer Tosunoğlu
Turkish Journal of Zoology
In this study, the first case of aberrant coloration, namely xanthochroism or xanthism, in the thinlip grey mullet, Chelon ramada (Teleostei: Mugilidae), was reported. The specimen was caught by a purse seiner in November 2019, in İzmir Bay, in the Aegean Sea, and was a female, with mature ovaries, which indicated that it had been in spawning migration or activity on the sampling date.
Coculture Model Of Blood-Brain Barrier On Electrospun Nanofibers, Mustafa Görkem Özyurt, Ece Bayir, Şule Doğan, Şükrü Öztürk, Ayli̇n Şendemi̇r
Coculture Model Of Blood-Brain Barrier On Electrospun Nanofibers, Mustafa Görkem Özyurt, Ece Bayir, Şule Doğan, Şükrü Öztürk, Ayli̇n Şendemi̇r
Turkish Journal of Biology
The blood-brain barrier (BBB) is a control mechanism that limits the diffusion of many substances to the central nervous system (CNS). In this study, we designed an in-vitro 3-dimensional BBB system to obtain a fast and reliable model to mimic drug delivery characteristics of the CNS. A support membrane of polycaprolactone nanofiber surfaces was prepared using electrospinning. After confirming the fiber morphology and size, endothelial cells (HUVEC) and glial cells were cultured on either side of this membrane. The model's similarity to in vivo physiology was tested with a home-designed transmembrane resistance (TR) device, with positive and negative control molecules. …
Akt-Mediated Phosphorylation Of Twist1 Is Essential For Breast Cancer Cell Metastasis, Mustafa Gökhan Ertosun, Suray Pehli̇vanoğlu, Sayra Di̇lmaç, Gamze Tanriöver, Osman Ni̇dai̇ Özeş
Akt-Mediated Phosphorylation Of Twist1 Is Essential For Breast Cancer Cell Metastasis, Mustafa Gökhan Ertosun, Suray Pehli̇vanoğlu, Sayra Di̇lmaç, Gamze Tanriöver, Osman Ni̇dai̇ Özeş
Turkish Journal of Biology
Previously, it was shown that human TWIST1 (basic helix-loop-helix (b-HLH) is phosphorylated by Akt kinase at S42, T121, and S123. To show in vivo effect of these phosphorylations, we created mouse TWIST1 expression vector and converted the codons of S42, T125, and S127 to unphosphorylatable alanine and phosphorylation mimicking Glutamic acid. We hypothesized that alanine mutants would inhibit the metastatic ability of 4T1 cells while glutamic acid mutants would convert nonmetastatic 67NR cells into metastatic phenotype. To confirm this hypothesis, we created metastatic 4T1 and nonmetastatic 67NR cells expressing alanine mutants and glutamic acid mutants mouse TWIST1, respectively. Then, we …
Simultaneous Production Of Alpha And Beta Amylase Enzymes Using Separate Gene Bearing Recombinant Vectors In The Same Escherichia Coli Cells, Di̇lek Özcan Yardim, Hi̇kmet Murat Si̇pahi̇oğlu
Simultaneous Production Of Alpha And Beta Amylase Enzymes Using Separate Gene Bearing Recombinant Vectors In The Same Escherichia Coli Cells, Di̇lek Özcan Yardim, Hi̇kmet Murat Si̇pahi̇oğlu
Turkish Journal of Biology
The present study describes the simultaneous expression of thermostable industrial alpha (α) and beta (ß) amylase enzymes that have been used widely in starch industry. Genomic DNA of Bacillus stearothermophilus DSM 22 strain for α amylase and, Thermoanaerobacterium (Clostridium) thermosulfurogenes DSM 2229 strain for ß amylase were used as gene sources. Both genes were ligated into pETDuet-1 expression vector separately and resulting recombinant vectors were transformed into Escherichia coli BL21 competent cells by electroporation. The cells were first transformed by pETDuet-1/ αAmy recombinant plasmid, then the competent cells carrying this plasmid were prepared for the transformation of pETDuet-1/ ßAmy plasmid. …
Genetic Diversity Of Pinto And Fresh Bean (Phaseolus Vulgaris L.) Germplasm Collected From Erzincan Province Of Turkey By Inter-Primer Binding Site (Ipbs) Retrotransposon Markers, Hali̇l İbrahi̇m Öztürk, Ati̇lla Dursun, Arash Hosseinpour, Kami̇l Hali̇loğlu
Genetic Diversity Of Pinto And Fresh Bean (Phaseolus Vulgaris L.) Germplasm Collected From Erzincan Province Of Turkey By Inter-Primer Binding Site (Ipbs) Retrotransposon Markers, Hali̇l İbrahi̇m Öztürk, Ati̇lla Dursun, Arash Hosseinpour, Kami̇l Hali̇loğlu
Turkish Journal of Agriculture and Forestry
In this study, genetic diversity among 71 bean genotypes (41 pinto beans and 30 fresh bean genotypes) and 4 commercial cultivars (Aleyna, Gina, Perolar, and Serra) commonly grown at Erzincan province in Turkey were investigated. The iPBS (inter-primer binding site) markers were used to investigate the genetic diversity of the genotypes. Polymorphism ratio was identified as 100% in all primers. Twenty-seven primers were studied and number of alleles in primers varied between 13?69 (with an average value of 37.14). According to cluster analysis based on iPBS data, genotypes were divided into 2 groups. Polymorphic information content (PIC) values varied between …