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Antioxidant Potential Of Sulfenimides In Waste Walnut Oil Biodiesel: Kinetic Stability, Phosphomolybdenum Activity, And Reducing Power Capacity, Nalan Türköz Karakullukçu, Hasan Yakan, Volkan Murat Yilmaz, Hali̇t Muğlu, Semi̇ha Yeni̇gün, Hali̇l Kütük

Turkish Journal of Chemistry

This study investigated the influence of synthetic sulfenimides on biodiesel–diesel fuel blends. Three previously synthesized sulfenimide derivatives were structurally characterized using spectroscopic techniques. We evaluated their antioxidant properties through phosphomolybdenum activity and reducing power capacity assays. The tested fuel samples were designated as D100, B10D90, B10D90_AA (ascorbic acid), B10D90_3, B10D90_2, and B10D90_1. The effect of adding 2000 ppm of the additive was measured using an Oxifast instrument following the ASTM D7545 standard, and the results were compared to those of the chemical antioxidant ascorbic acid. Inhibition time values were derived from the oxidation stability results. The starting temperatures for crystallization …

Investigating The Structure And Bioactivity Of Lanthanum Coordination Compounds, Shantanu Kadam, Bhushan Dhale, Bapu Yamgar, Swaminath Bhattar

Turkish Journal of Chemistry

Lanthanum metal complexes were synthesized using a classical condensation method by reacting lanthanum nitrate salts with a bidentate ligand in a 1:2:1 molar ratio (M:L:L). The formation and structure of the resulting complexes were confirmed through a combination of analytical techniques, including Fourier transformation infrared spectroscopy, thermal gravimetric analysis, X-ray diffraction, elemental microanalysis, and scanning electron microscopy. The lanthanum complexes synthesized exhibited strong in vitro antimicrobial activity. Antibacterial screening showed inhibition zones of 18–26 mm against Staphylococcus aureus and Escherichia coli, surpassing those of the reference drug ciprofloxacin (16–20 mm). Antifungal studies demonstrated inhibition zones of 15–23 mm against Candida …

Cover And Contents

Turkish Journal of Veterinary & Animal Sciences

No abstract provided.

Comparison Of The Mars And Xgboost Algorithms For Predicting Body Weight In Kalahari Red Goats, Louis Thobela Tyasi, Cem Tirink, Kwena Mokoena, Hasan Önder, Uğur Şen, Demet Çanga Boğa, Tolga Tolun, İsmai̇l Gök, Yüksel Aksoy, Lütfi̇ Bayyurt, Ömer Faruk Yilmaz

Turkish Journal of Veterinary & Animal Sciences

Estimating goat body weight from morphometric traits is essential for growth monitoring, health management, and welfare. Accurate weight informs nutrition, clinical interventions, and mating decisions. In this study, the MARS and XGBoost algorithms were used to estimate the live weight of Kalahari Red goats based on body measurements. A dataset containing body length (BL), birth type (single, twin, or triplet), withers height (WH), rump height (RH), and heart girth (HG) information for 200 goats was used in the training and testing of the models. The performances of the models were evaluated with the goodness-of-fit criteria. XGBoost showed a performance of …

Hatchability And Nestling Viability In An Extremely Short-Beaked Pigeon Breed, Türker Savaş, Hakan Erdem, Cemi̇l Tölü

Turkish Journal of Veterinary & Animal Sciences

The selection of hobby animals for breeding by enthusiasts is often based on aesthetic considerations, which can have a negative impact on the animals’ biology. Furthermore, “extreme traits” that deviate from ancestral norms, such as short beaks in pigeons, can be detrimental to the animal’s welfare. Beaks perform many essential functions, such as facilitating feed intake and eggshell breaking. The present study investigates possible hatching problems and the nestling viability of short-beak pigeons through a study of the breeding records of Mısıri (short beak), Baska (medium beak), and Turkish Dönek (normal beak) pigeons, as well as data from one breeding …

Determination Of Cortisol Concentrations Using Different Biomarkers In Dairy Goats During Pregnancy, Fatma Mi̇ra Güven, Erkan Pehli̇van

Turkish Journal of Veterinary & Animal Sciences

Pregnancy is considered one of the most physiologically stressful periods in mammals. In the present study, serum and hair cortisol concentrations were measured in nine female Akkeçi goats, including five primiparous (1.5 years old) and four multiparous (3.5 years old), to evaluate chronic stress during pregnancy. Hair samples were collected in October, November, and December following the introduction of bucks to the herd and within the first 12 h postpartum (corresponding to the 1st, 2nd, 3rd, and 7th sampling times). Hair samples were not collected in January, February, or March (the 4th, 5th, and 6th sampling times) due to insufficient …

Effects Of Zinc-Reinforced Clinoptilolite On Hematological Parameters, Igg Levels, And Enzyme Histochemistry In Fattening Lambs, İhsan Kisadere, Muhi̇tti̇n Zengi̇n, Özkan Demi̇rbaş, Mehmet Faruk Aydin

Turkish Journal of Veterinary & Animal Sciences

The study aimed to determine the effects of zinc-reinforced clinoptilolite supplementation to the diet on selected hematological parameters, serum immunoglobulin G (IgG) concentrations, and enzyme histochemical characteristics in fattening lambs. For this purpose, 40 healthy male lambs were randomly allocated into five equal groups: control (C; n = 8), natural clinoptilolite (NC; n = 8), zinc (ZN; n = 8), natural clinoptilolite plus zinc (NCZN; n = 8), and zinc-reinforced clinoptilolite (ZNRC; n = 8). All animals were housed in individual pens, and the supplementation period continued for 42 days. Blood samples were collected before the trial (day 0) and …

Human Bone Marrow-Mesenchymal Stem Cells Differentiation Into Brain-Like Endothelial Cells, Yomna Soliman, Güli̇n Baran, Nur Mustafaoğlu

Turkish Journal of Biology

Background/aim: Brain microvascular endothelial cells (BMECs), which constitute the blood–brain barrier (BBB), are essential for maintaining central nervous system homeostasis. Like BMECs, multipotent mesenchymal stem cells (MSCs) originate from the mesodermal lineage. Thus, MSCs may serve as a direct and efficient cellular source for BMEC-like differentiation. Notably, differentiation of human induced pluripotent stem cells (hiPSCs) into BMECs typically involves a 2-step protocol: inducing mesodermal commitment followed by endothelial specification. In contrast, direct differentiation from MSCs could bypass the initial mesodermal induction step, offering a streamlined alternative. This study tested a novel strategy for differentiating MSCs into brain-like endothelial cells (BLECs), …

Investigation Of Antimicrobial Synergism Of Actinomycin Derivatives From Streptomyces Parvus 35m1 Against Escherichia Coli Atcc 25922, Özge Can, Mustafa Ünver Kurt, Meli̇s Küçüksolak, Ataç Uzel, Erdal Bedi̇r

Turkish Journal of Biology

Background/aim: Limited drug development and increased antibiotic tolerance among Gram-negative bacteria have led researchers to consider combination therapy. Actinomycin derivatives, particularly actinomycin D, exhibit a wide range of bioactivities, including antibacterial effects. However, actinomycin D is less effective against Gram-negative pathogens. Therefore, it is essential to demonstrate the synergy of actinomycin D and its derivatives with clinically known antibiotics against Escherichia coli ATCC 25922 and investigate the effects on cellular morphology.

Materials and methods: Streptomyces parvus 35M1 isolated from coastal sediment in İzmir/Türkiye was identified via genome sequencing. Large-scale (30 L) fermentation followed by chromatographic purification yielded compounds 1 (actinomycin …

Transcriptomic Identification And Developmental Mapping Of Nrg3b Expression In Zebrafish, Elham Tarahomi, Nuray Soğünmez Erdoğan

Turkish Journal of Biology

Background/aim: Neuregulin 3 (NRG3) is an epidermal growth factor-like ligand that is involved in neuronal circuit formation in mammals. However, the expression profile of its zebrafish ortholog, nrg3b, remains poorly defined. The transcriptomic analyses of zebrafish sco-spondin mutants, which display alterations in their neurodevelopmental pathways, have indicated potential dysregulation of Nrg3b. Guided by these insights, this study aimed to characterize the temporal and spatial expression patterns of nrg3b in vivo in embryonic and adult zebrafish.

Materials and methods: Publicly available RNA-seq data from heterozygous and maternal-zygotic zebrafish sco-spondin mutants at 5, 15, and 30 days postfertilization (dpf) were analyzed to …

Heavy Metals As Endocrine Disruptors, Arzu Or Koca

Turkish Journal of Medical Sciences

Heavy metals are widely recognized as endocrine-disrupting agents primarily originating from anthropogenic sources and persisting in soil, air, and water. This review aims to present an updated and comprehensive synthesis of current evidence regarding the endocrine-disrupting effects of heavy metals, with particular emphasis on their roles in the pathogenesis of common endocrine and metabolic disorders. The toxicological impact of these elements depends on the level and duration of exposure, their chemical form, and the biological susceptibility of target tissues. Chronic exposure, even at low doses, has been implicated in the development of diabetes mellitus, obesity, autoimmune thyroiditis, thyroid cancer, pubertal …

Involvement Of Swap-70 In Proteolipid Protein-Induced Experimental Autoimmune Encephalomyelitis, Canan Ulusoy, Gi̇zem Koral, Fatma Akpunar Salman, Meli̇s Şen, Emi̇ne Şekerdağ Kiliç, Recai̇ Türkoğlu, Cem İsmai̇l Küçükali̇, Yasemi̇n Gürsoy Özdemi̇r, Vuslat Yilmaz, Erdem Tüzün

Turkish Journal of Medical Sciences

Background/aim: Multiple sclerosis (MS) is a chronic demyelinating inflammatory disease of the central nervous system. Studies have shown that B cells may play an important role in the induction and progression of MS. Switch-associated protein 70 (SWAP-70) is a signal transduction molecule abundantly expressed in B cells and involved in B-cell polarization, directed migration, endothelial cell adhesion, and tissue homing. B-cell stimuli increase its expression. SWAP-70 has been implicated in the pathogenesis of autoimmune disorders, including MS. This study aims to investigate the effects of acquired SWAP-70 inhibition on immune cell subsets in experimental autoimmune encephalomyelitis (EAE).

Materials and methods: …

Oleanolic Acid–Chitosan Compound Inhibits Mitochondrial Autophagy And Malignant Transformation Of Lung Cancer Through The Pten/Akt Pathway, Abuli̇mi̇ti̇ Abulai̇ti̇, Xi̇aohong Sun, Waresijiang Yibulayin, Dan He, Kemi̇ng Xu, Xi̇ayi̇mai̇erdan Yi̇bulayi̇n

Turkish Journal of Medical Sciences

Background/aim: Oleanolic acid–chitosan compound (OAC) shows potent antinonsmall cell lung cancer (NSCLC) activity, but its mechanisms remain unclear. This study elucidates how OAC modulates autophagy and apoptosis via the Phosphatase and Tensin Homolog/Protein Kinase B (PTEN/AKT) signaling pathway.

Materials and methods: Oleanolic acid was coupled with chitosan to synthesize OAC. A549 and MRC-5 cells were cultured in Dulbecco’s Modified Eagle Medium and Minimum Essential Medium, respectively, supplemented with 10% fetal bovine serum and penicillin–streptomycin. Cells were pretreated with chloroquine before OAC treatment. Cell viability was assessed using the CCK- 8 assay, while 5-bromo-2′-deoxyuridine (BrdU) and colony formation tests were employed …

Contribution Of Adenosine A2a Receptor Agonist And Antagonist On Ovarian Ischemia/Reperfusion Injury In Rats, Azad Mammadov, Abdullah Tuncay Demi̇ryürek, Ahmet Saracaloğlu, Cahi̇t Demi̇rkiran, İsmai̇l Tuncer Deği̇m, Ömer Eronat, Şeni̇z Demi̇ryürek

Turkish Journal of Medical Sciences

Background/aim: To determine the effects of an A2A receptor agonist regadenoson, an A2A receptor antagonist istradefylline, and istradefylline nanosuspension on ovarian ischemia/reperfusion (I/R) injury in rats.

Materials and methods: A total of 80 female rats were divided into 10 groups: sham, ovarian I/R, blank nanosuspension + ovarian I/R, regadenoson (3 μg/kg) + ovarian I/R, regadenoson (30 μg/kg) + ovarian I/R, istradefylline (0.3 mg/kg) + ovarian I/R, istradefylline (3 mg/kg) + ovarian I/R, istradefylline-loaded nanosuspension (3 mg/kg) + ovarian I/R, istradefylline (3 mg/kg) + regadenoson (30 μg/kg) + ovarian I/R, and istradefylline-loaded nanosuspension (3 mg/kg) + regadenoson (30 μg/kg) + ovarian …

Mandibular Extension As A Trigger Of The Proprioceptive Trigeminocardiac Reflex, Massimo Conti, Giovanna Traina, Daniele Tonlorenzi

Turkish Journal of Medical Sciences

The trigeminocardiac reflex (TCR) is a physiological response characterized by a reduction in heart rate and arterial blood pressure following stimulation of any branch of the fifth cranial nerve. This review presents a novel mechanism of TCR induction through proprioceptive activation of the trigeminal nerve via mandibular extension (ME). Accordingly, it is referred to as the “proprioceptive trigeminocardiac reflex” (pTCR). An overview of the existing literature on ME-evoked TCR in humans and animals is presented, with particular emphasis on evidence of cerebral microcirculatory alterations. The magnitude of cardiovascular responses appears to depend on the duration of ME, with repeated applications …

Feeding Time Index And Mortality In Intensive Care Stroke Patients: An Exploratory Cohort Study, Nevzat Mehmet Mutlu, Duygu Karaköse Çalişkan, Tülay Tunçer Peker, Özlem Balkiz Soyal, Ayşe Pinar Ti̇ti̇z, Behi̇ye Deni̇z Kosovali, Göksal Günerhan, Büşra Tezcan

Turkish Journal of Medical Sciences

Background/aim: Stroke is a major cause of morbidity and mortality worldwide, with especially high mortality in intensive care unit (ICU) patients, whose prognosis is worsened by dysphagia, malnutrition, and aspiration risk. The Feeding Time Index (FTI)—defined as the ratio of feeding days to total ICU length of stay—quantified nutritional exposure. This exploratory cohort study aimed to evaluate the association between FTI and mortality in ICU patients with acute ischemic stroke (IS) or hemorrhagic stroke (HS) and to examine the potential role of FTI, together with the Acute Physiology and Chronic Health Evaluation II (APACHE II) score and oral feeding status, …

Association Of Mir-34a With Metastatic Progression Through The Foxo3a–Sirt1 Regulatory Axis In Breast Cancer, Banu Şahi̇n, İlker Batuhan Bural, Hüseyi̇n Özcan, Sendegül Yildirim, Gamze Tanriöver, Şükran Burçak Yoldaş

Turkish Journal of Medical Sciences

Background/aim: Breast cancer represents the foremost cause of cancer-related mortality among women worldwide and is characterized by a markedly high metastatic potential, contributing substantially to its clinical severity and poor prognosis. This study aimed to evaluate the interrelationship among silent information regulator (SIRT1), Forkhead box O3a (FoxO3a), and microRNA-34a (miR- 34a), the latter of which promotes apoptosis by suppressing the proliferation, migration, and invasion of breast cancer cells. Specifically, we investigated the tumor microenvironment associated with metastatic progression of malignant primary tumors, the influence of nonmetastatic (benign) tumors, and the potential roles of these proteins in both primary tumor development …

Neuroendocrine Effects Of Exogenous Adropin Administration On The Hypothalamic Pituitary Testicular Axis In Male Rats, Ersen Eraslan, Ayhan Tanyeli̇, Mustafa Can Güler, Asli Özbek Bi̇lgi̇n, Fazi̇le Nur Eki̇nci̇ Akdemi̇r, Eli̇f Polat, Seli̇m Çomakli, Nezahat Kurt, Tuğba Bal Taştan

Turkish Journal of Medical Sciences

Background/aim: Obesity impairs male fertility through metabolic dysfunction, oxidative stress, and disruption of the hypothalamic– pituitary–testicular (HPT) axis. Adropin (ADR), a peptide hormone whose circulating levels are reduced in obesity, plays emerging roles in metabolic homeostasis; however, its involvement in reproductive endocrine regulation remains unclear. The present study was conducted in healthy, nonobese male rats and aimed to investigate the neuroendocrine and testicular effects of exogenous ADR administration, focusing on circulating reproductive hormones, hypothalamic regulatory peptides, and testicular antioxidant pathways.

Materials and methods: Thirty-two male Wistar rats were randomized into control, sham, low-dose ADR (4 μg/kg/day), and high-dose ADR (40 …

Fitness Cost And Biofilm Formation In Fosfomycin-Resistant Clinical Escherichia Coli And Klebsiella Pneumoniae Isolates, Mustafa Ökeer, Sabi̇re Şöhret Aydemi̇r, Bayri Eraç

Turkish Journal of Medical Sciences

Background/aim: Fosfomycin has regained importance owing to its unique mechanism of action and effectiveness against extended-spectrum β-lactamase-producing Gram-negative bacteria. This study aimed to evaluate the biological fitness cost associated with fosfomycin resistance and its impact on biofilm formation in clinical Enterobacteriaceae isolates.

Materials and methods: A total of 78 Escherichia coli and 34 Klebsiella pneumoniae strains isolated from urine samples at Ege University Hospital were analyzed. Fosfomycin minimum inhibitory concentrations (MICs) were determined using the reference agar dilution method. Resistance was induced by exposing two K. pneumoniae strains with a fosfomycin MIC of 4 μg/mL and two E. coli strains …

Complete Genome Characterization Of A New Alphapartitivirus Identified In The Ectomycorrhizal Fungus Lactarius Mediterraneensis, Aigul Kali̇yeva, Ergi̇n Şahi̇n, Gülce Edi̇ş, Ilgaz Akata

Turkish Journal of Botany

Viruses that naturally infect fungi capable of forming mycorrhizal symbioses remain poorly studied. In the present study, a new partitivirus associated with the basidiomycete mycorrhizal fungus Lactarius mediterraneensis was identified and characterized, and it was designated as Lactarius mediterraneensis partitivirus 1 (LmPV1). The complete genome of LmPV1 was determined through high throughput sequencing of double-stranded RNA (dsRNA) extracts and confirmed by Sanger sequencing of RLM-RACE PCR amplicons. T he genome comprises two dsRNA segments, 1899 bp and 1957 bp, each containing a single open reading frame (ORF) a putative RNA-dependent RNA polymerase (RdRp) and a capsid protein (CP). Comparative analysis …

Cover And Contents

Turkish Journal of Zoology

No abstract provided.

Zonation-Dependent Distribution Of Microplastic Occurrence In Patella Caerulea From Mersin Coast, Türkiye, Ezgi̇ Deği̇rmenci̇, Nuray Çi̇ftçi̇, Sedat Gündoğdu, Deni̇z Ayas

Turkish Journal of Zoology

Increasing plastic pollution has become a critical environmental issue, leading to  challenges in management. Specifically, microplastics (MPs) are of particular concern  because they can persist in aquatic ecosystems and adversely affect marine  organisms. The objective of this study was to assess the occurrence of MPs  in the soft tissues of Patella caerulea (Linnaeus, 1758) collected from the Mersin  Viranşehir coastal area. As no specimens were found in the supralittoral zone, the  decision was taken to conduct sampling only in the mediolittoral and infralittoral  zones. The total sampling area was 24 m2 divided into three 4-m2 plots in each zone.  A …

Blinking Without Eyelids: First Video-Documented Evidence Of A Blink-Like Reflex In Ophisops Elegans (Reptilia: Lacertidae), Turan Meri̇ç Çelebi̇, Yusuf Çeli̇kaği, Tuana Kinay, Arda Cem Kuyucu, Muammer Kurnaz, Mehmet Kürşat Şahi̇n

Turkish Journal of Zoology

Eyelids play a crucial role in protecting the eyes of vertebrates; however, certain  reptile species, such as Ophisops elegans, completely lack movable eyelids. In this  study, we present the first video-documented evidence of a blink-like reflex in O.  elegans, captured through endoscopic field observations and corroborated by laboratory video analysis. The observed movement consisted of a brief convex  deformation of the ocular surface, lasting approximately 0.3 s and resembling a blink  despite the presence of a fixed transparent brille. This behavior was observed once in  the field and twice under controlled laboratory conditions. We propose that O.  elegans may employ …

Growth Patterns And The Shift From Predominantly Female To Balanced Sex Ratios In Carassius Gibelio (Bloch, 1782): A Comparative Study Of Lotic And Lentic Populations In  Serbia, Tamara Mitić, Jelena Čanak Atlagić, Ana Marić, Jelena Stanković Ristić, Nikola Marinković, Momir Paunović, Predrag Simonović

Turkish Journal of Zoology

Since its introduction into Serbian watercourses, the invasive Carassius gibelio (Bloch, 1782) (Prussian carp) has spread rapidly. This paper provides an up-to-date overview of the sex ratio, age structure, and growth parameters in Serbian  populations of this fish and describes how growth varies in two contrasting  ecosystems: lotic and lentic. A total of 133 individuals were sampled. The individuals  from lentic habitats were longer on average, with no significant differences in average  weight or age between the two ecosystem types. There was a difference in  the sex ratio between the ecosystems, as indicated by a higher proportion of males in …

Habitat Diversity Or Altitudinal Gradient? Which Factor Better Explains Ground Beetle (Coleoptera: Carabidae) Biodiversity? A Case Study From Davraz Mountain (Isparta, Türkiye), Ebru Ceren Fi̇dan, Ali̇ Gök

Turkish Journal of Zoology

Ground beetle (Carabidae) species diversity and spatial distribution were surveyed  across five habitat types along an elevational gradient on Davraz Mountain, a  biogeographical transition area in southwestern Türkiye. The analyses showed that  habitat heterogeneity—particularly soil moisture and texture—exerts a stronger  influence on carabid diversity than elevation. Sørensen’s and Jaccard similarity  indices showed strong faunal overlap between some sampling areas, while  multivariate principal components and canonical correspondence analyses verified  distinct environmental gradients influencing community structure. Diversity indices  indicated varying levels of species richness and evenness across sampling areas.  The data highlight the importance of fine-scaled habitat features in driving ground  beetle …

Dna Metabarcoding Approach To The Determination Of The Diet Spectrum Of The Common  Sunbleak Leucaspius Delineatus (Heckel, 1843), Elena V. Dzyuba, Yurij S. Bukin, Bakhtiar E. Bogdanov, Yulia P. Sapozhnikova, Natalia N. Denikina

Turkish Journal of Zoology

The common sunbleak (Leucaspius delineatus) is an invasive fish found in Siberian  water bodies, the trophic interactions and impact on local ecosystems of which  remain poorly understood. Traditional diet analyses are limited by the mechanical  damage to the prey. For the present study, therefore, we employed DNA  metabarcoding of the cytochrome c oxidase I (cox1) gene to analyze the digestive  tract contents of the common sunbleak obtained from Irkutsk Reservoir. Our analysis  revealed 53 operational taxonomic units (OTUs), with sequences of amphibiotic  insects (58.66%) and fish (34.10%) being the most prevalent. A significant proportion  of the fish DNA, including sequences …

Bioerosion And Encrustation As Paleoenvironmental Indicators In Upper Cretaceous Corals, Aruma Formation, Saudi Arabia, Abdelbaset S. El-Sorogy, Huriye Demi̇rcan, Khaled Al-Kahtany, Taisser Zumlot, Talal Alharbi, Mohamed Tawfik

Turkish Journal of Earth Sciences

This study documents and interprets bioerosion and encrustation traces on Upper Cretaceous scleractinian corals from the Hajajah Member of the Aruma Formation in northern Khashm Buwaibiyat, central Saudi Arabia. Fieldwork in 2023 and 2024 involved detailed bed-by-bed stratigraphic logging, ichnological assessment, and fossil collection across marl and limestone units. A total of 213 coral specimens with bioerosional features were analyzed, leading to the identification of 10 ichnospecies across 5 ichnogenera, including Gastrochaenolites, Entobia, Caulostrepsis, Rogerella, and Labyrintichnus. These traces reflect a range of ethological categories, primarily domichnia, indicating permanent dwelling structures by polychaetes, sponges, bivalves, barnacles, and crustaceans. The Hajajah …

Effect Of Nettle (Urtica Dioica L.) Seed Powder Supplementation On Some Important Quality Characteristics Of Cakes, Esra İrem Can, Kadi̇r Çebi̇

Turkish Journal of Agriculture and Forestry

The nutritional adjustment of food products has gained popularity in recent years as consumer interest in healthy eating has increased. Cake is a widely consumed cereal-based product containing such key nutrients as carbohydrate, fat, protein, fiber, vitamins, and minerals. In the present study, crust and crumb color, specific volume, microstructure, antimicrobial activity, total phenolic content, antioxidant activity, and sensory analyses were evaluated in four cake groups: a control cake (IT0) and cakes supplemented with 1% (IT1), 3% (IT2), and 5% (IT3) nettle seed powder. The addition of nettle seed powder to the cakes significantly reduced the crust (L*, a* and …

Eucommia Ulmoides Extract Attenuates Oxidative Stress And Promotes Melanogenesis Via Wnt/Β-Catenin Signaling In B16 Cells And Mice, Xiaojin Liu, Yaqian Qiu, Xiaobing Lv, Lei Chang, Tiancheng Ji, Yefan Gu, Shuyue Chen

Turkish Journal of Biology

Background/aim: Oxidative stress is a major contributor to melanocyte dysfunction and hair graying by impairing key signaling pathways. Eucommia ulmoides bark extract (EUE), rich in antioxidant phytochemicals, has shown potential in combating oxidative damage. This study investigated the protective and promelanogenic effects of EUE under hydrogen peroxide (H₂O₂)-induced oxidative stress, with a focus on the Wnt/β-catenin signaling pathway. Materials and methods: An oxidative stress model was established using B16 cells and a C57BL/6 mouse hair follicle model. Results: EUE significantly improved melanocyte survival and reduced intracellular reactive oxygen species (ROS). Mechanistically, EUE activated the Wnt/β-catenin pathway, leading to upregulation of …

Effects Of Different Perfluoroalkyl Substances On Rice Morphology, Physiology, And Biochemistry, Maryam M. Alomran, Muhammad Aqeel, Noreen Khalid, Noreen Akhter, Muhammad Kashif Irshad, Suliman Mohammed Suliman Alghanem, Fahad Mohammed Alzuaibr, Saher Nawaz, Omar Mahmoud Alzoubi, Muhammad Usman Akbar, Ali Noman

Turkish Journal of Agriculture and Forestry

Perfluoroalkyl substances (PFASs) are synthetic organic compounds that have not been extensively studied in natural environments. The current study aimed to explore how PFASs, including perfluorooctane sulfonic acid (PFOS), perfluorobutane sulfonate (PFBS), perfluorohexanoate (PFHxA), perfluorotetradecanoate (PFTeDA), and perfluorobutanoate (PFBA), affect rice plants and influence their metabolism. These substances had a notable impact on root and shoot growth, reducing fresh and dry weights across various treatments compared to the control. These attributes were the least affected by PFOS treatment. PFBA treatment had significant adverse effects on chlorophyll a, b, and total chlorophyll levels, followed by the effects of PFHxA and PFTeDA. …