Open Access. Powered by Scholars. Published by Universities.®
- Keyword
-
- Saudi Arabia (3)
- COVID-19 (2)
- Hospitalization (2)
- APRI (1)
- AST (1)
-
- Acute kidney injury (1)
- Algorithms (1)
- Allograft tolerance (1)
- Antibiotic stewardship (1)
- Antibiotics (1)
- Anxiety (1)
- Artificial intelligence (1)
- Attitude (1)
- Balance (1)
- Behaviour (1)
- Bibliometric analysis (1)
- Bibliometrics (1)
- Biomechanics (1)
- Blood transfusion (1)
- CMV (1)
- Center of mass (1)
- Center of pressure (1)
- Childhood obesity (1)
- Chimeric antigen receptor (1)
- Chronic disease prevention (1)
- Citation analysis (1)
- Clinical decision rules (1)
- Clinical guideline (1)
- Communicable diseases (1)
- Computer Simulation (1)
Articles 31 - 60 of 698
Full-Text Articles in Entire DC Network
Epidemiology And Risk Factors Of Methicillin-Resistant Staphylococcus Aureus (Mrsa) Infections In A Tertiary Care Hospital In Saudi Arabia: An 8-Year Retrospective Analysis, Jawharah S. Alhazmi, Ameera S. Al-Khaldi, Naoufel M. Kaabia, Nabiha A. Bouafia, Yasser K. Mohammed, Abdulrahman N. Odayani
Epidemiology And Risk Factors Of Methicillin-Resistant Staphylococcus Aureus (Mrsa) Infections In A Tertiary Care Hospital In Saudi Arabia: An 8-Year Retrospective Analysis, Jawharah S. Alhazmi, Ameera S. Al-Khaldi, Naoufel M. Kaabia, Nabiha A. Bouafia, Yasser K. Mohammed, Abdulrahman N. Odayani
Saudi Medical Journal
ABSTRACT Objectives: To control the spread of methicillin-resistant Staphylococcus aureus (MRSA) in healthcare institutions, understanding its local epidemiology is essential. We aimed to investigate the epidemiological, clinical, and bacteriological features of MRSA cases and compare their origin (hospital-acquired versus [vs.] community-acquired) and patient age (pediatric vs. adult). Methods: A retrospective survey was conducted using the electronic database of all MRSA cases reported to the Infection Prevention and Control Center at a tertiary care hospital in Saudi Arabia from 2012 to 2020. We collected epidemiological, clinical, and microbiological data and performed comparative analyses between groups using appropriate statistical tests. Results: Among …
A 12-Year Analysis Of Seasonal Patterns And Disease Dynamics Of Cutaneous Leishmaniasis In Saudi Arabia, Basmah F. Alharbi, Mawahib A. Ahmed
A 12-Year Analysis Of Seasonal Patterns And Disease Dynamics Of Cutaneous Leishmaniasis In Saudi Arabia, Basmah F. Alharbi, Mawahib A. Ahmed
Saudi Medical Journal
ABSTRACT Objectives: To investigate seasonal patterns of cutaneous leishmaniasis in Saudi Arabia, examining how incidence rates vary throughout the year. By exploring these dynamics, we aim to gain insights that could improve understanding and prevention strategies for this disease. Cutaneous leishmaniasis , a global parasitic disease affecting millions, presents a significant health challenge. Methods: This study analyzed epidemiological data from Saudi Arabia from January 2012 to December 2023, using records from the Ministry of Health to document incidence. Statistical methods, including Chi-squared tests and ANOVA, were employed, along with correlation and regression analyses to forecast future cases. Results: The findings …
Patterns Of Dermatological Emergencies At A Tertiary Hospital In Southwestern Saudi Arabia: A Descriptive Study, Hamad A. Alfahaad
Patterns Of Dermatological Emergencies At A Tertiary Hospital In Southwestern Saudi Arabia: A Descriptive Study, Hamad A. Alfahaad
Saudi Medical Journal
ABSTRACT Objectives: To examine the patterns and characteristics of dermatological emergencies managed at a tertiary hospital in the Southwest Region of Saudi Arabia. Methods: This study employed a retrospective cross-sectional design conducted at King Khalid Hospital in Najran, Saudi Arabia. The study included patients who either visited the dermatology or emergency departments or were hospitalized due to dermatological conditions treated between January 2019 and December 2024. Results: The study included 126 patients, with an almost equal distribution of males (50.8%) and females (49.2%), predominantly Saudi nationals (78.6%). Most patients were aged 18-60 (65.1%) years. The most common skin lesion was …
Osteoporosis Screening Practice At The National Guard Affiliated Primary Care Centers, Riyadh, Saudi Arabia, Moath Abdulmohsen Alkathiri, Duaa Abdullah Alammari
Osteoporosis Screening Practice At The National Guard Affiliated Primary Care Centers, Riyadh, Saudi Arabia, Moath Abdulmohsen Alkathiri, Duaa Abdullah Alammari
Saudi Medical Journal
ABSTRACT Objectives: To assess the use of osteoporosis screening tests in average-risk individuals at primary healthcare centers affiliated with the Ministry of National Guard Health Affairs in Riyadh, Saudi Arabia, between 2016 and 2023. Methods: Data were presented using frequencies n (%), mean, and standard deviation. Chi-square, t-test, and ANOVA tests were used for bivariate comparisons to evaluate test completion and prevalence estimates of osteopenia and osteoporosis. Binary logistic regression models were used to identify the factors associated with high odds of bone mineral density (BMD) test ordering and completion. For all analyses, a p ≤0.05 was considered statistically significant. …
The Impact Of Antibiotic Prophylaxis Appropriateness, Duration And Associated Cost On The Rate Of Surgical Site Infection At A Tertiary Hospital In Riyadh, Saudi Arabia: A Retrospective Study, Amal Bin Akresh, Deema S. Alzeet, Njoud Z. Alshalan, Marwa M. Alhawsawi, Nada A. Alsaleh, Reem A. Binsuwaidan, Alaa A. Alhubaishi, Abdulaziz I. Altowaijri, Najla N. Alebedah, Nisreen M. Sherbeeni, Lina I. Alnajjar
The Impact Of Antibiotic Prophylaxis Appropriateness, Duration And Associated Cost On The Rate Of Surgical Site Infection At A Tertiary Hospital In Riyadh, Saudi Arabia: A Retrospective Study, Amal Bin Akresh, Deema S. Alzeet, Njoud Z. Alshalan, Marwa M. Alhawsawi, Nada A. Alsaleh, Reem A. Binsuwaidan, Alaa A. Alhubaishi, Abdulaziz I. Altowaijri, Najla N. Alebedah, Nisreen M. Sherbeeni, Lina I. Alnajjar
Saudi Medical Journal
ABSTRACT Objectives: To evaluate the incidence of surgical site infections (SSIs) based on compliance with surgical antibiotic protocols and the duration of surgical antibiotic prophylaxis (SAP). Secondary objectives include assessing 30-day rehospitalization rates, 30-day mortality, antibiotic-associated adverse events, and the estimated additional costs of prolonged antibiotic use in patients receiving long courses of antibiotics. Methods: This retrospective observational study was conducted at Prince Sultan Military Medical City from 2021 to 2022. It included adult patients who underwent elective surgery and received antibiotic prophylaxis. Patients were divided into 4 groups based on SAP compliance and prophylaxis duration. Using data from electronic …
Evaluation Of Hbsag And Hbeag Seroconversion Rates In Patients Diagnosed With Chronic Hepatitis B: A 10-Year Retrospective Analysis
Saudi Medical Journal
ABSTRACT Objectives: To analyze the seroconversion rates over a ten-year follow-up period. Chronic hepatitis B (CHB) remains a critical public health concern globally. The seroconversion rates of hepatitis B surface antigen (HBs Ag) and hepatitis B e antigen (HBe Ag) are pivotal in evaluating treatment efficacy. Treatment cessation is guided by the identification of patients who have HBsAg seroclearance and HBeAg seroconversion. Methods: A 2,300 CHB patients treated with nucleos(t)ide analogues (NUCs) from 2013 to 2023 included the study. Based on their alanine aminotransferase (ALT) levels and HBeAg status, patients were divided into four phases and assessed the rates of …
Comparative Study Of Pregnancy Risks In Different Maternal Age Groups, Amala Sunder, Yusuf Khaled Hadi, Noor Ammar Alkhuzaei, Nayla Jamal Bushaqer, Basma Darwish, Nawal Dayoub
Comparative Study Of Pregnancy Risks In Different Maternal Age Groups, Amala Sunder, Yusuf Khaled Hadi, Noor Ammar Alkhuzaei, Nayla Jamal Bushaqer, Basma Darwish, Nawal Dayoub
Saudi Medical Journal
ABSTRACT Objectives: To evaluate and compare pregnancy complications associated with varying maternal age groups. Methods: A retrospective analysis of singleton pregnancy outcomes at Bahrain Defense Force Hospital from January to December 2022. The study population was divided into 4 age groups: <25 years, 25-29 years, 30-34 years, and ≥35 years. Data on demographics, maternal and fetal characteristics were collected, and statistical significance was set at p <0.05. Univariate logistic regression was performed to analyze maternal and neonatal outcomes, adjusting for maternal factors. Results: The study included 2,972 women aged 17-55. Significant associations were found between maternal age and outcomes. Body mass index (BMI) was significantly linked to age ( p <0.01), with younger women having lower BMI. Gestational diabetes mellitus (GDM) was more common in women ≥35 years (11.5%) vs. those <25 years (6.6%, p =0.027). Intrauterine growth restriction (IUGR) was more prevalent in the <25 years age group ( p =0.041).Logistic regression showed women 30-34 years had a lower risk of GDM compared to 25-29 years (odds ratio [OR]: 0.544, CI: 0.365-0.811), and women <25 years had a higher risk of preterm delivery (OR: 1.365, CI: 1.015-1.837). Conclusion: Maternal age is an independent risk factor for various adverse outcomes. Younger women (<25) are at higher risk for preterm delivery and IUGR, while older women (≥35) have higher rates of GDM.
Patterns Of Antibiotic Resistance In Uropathogens Isolated From Pediatric Patients: A Multicenter Study, Zeyad A. Almatroudi, Abdullah M. Almazrou, Abdullah H. Aljomoai, Zaid M. Alsulami, Abdulaziz M. Alotaibi, Abdulmohsen A. Almutairi, Aiman El-Saed, Faisal A. Alsehli, Majid M. Alshamrani
Patterns Of Antibiotic Resistance In Uropathogens Isolated From Pediatric Patients: A Multicenter Study, Zeyad A. Almatroudi, Abdullah M. Almazrou, Abdullah H. Aljomoai, Zaid M. Alsulami, Abdulaziz M. Alotaibi, Abdulmohsen A. Almutairi, Aiman El-Saed, Faisal A. Alsehli, Majid M. Alshamrani
Saudi Medical Journal
ABSTRACT Objectives: To evaluate the antibiotic resistance patterns in common uropathogens isolated from pediatric patients. Methods: This was a retrospective chart review on the uropathogens causing first-time, community-acquired, symptomatic urinary tract infection (UTI). The data for this study was collected from one tertiary care hospital and 4 primary care centers in Riyadh, Saudi Arabia, with data spanning from 2017-2022. Diagnosis of UTIs was in line with the guidelines of the American Academy of Pediatrics. Results: Isolates were gathered from 610 patients, 101 (16.6%) of whom were male and 509 (83.4%) were female. The 3 most common species isolated were Escherichia …
Concordance Between Homeostatic Model Assessment And Triglyceride Glucose Index In Assessing Insulin Resistance Among Hiv-Infected Patients, Gokcen Gurkok Budak, Aslı Vatan, Ertuğrul Güçlü, Oğuz Karabay
Concordance Between Homeostatic Model Assessment And Triglyceride Glucose Index In Assessing Insulin Resistance Among Hiv-Infected Patients, Gokcen Gurkok Budak, Aslı Vatan, Ertuğrul Güçlü, Oğuz Karabay
Saudi Medical Journal
Objectives: To evaluate the concordance between the triglyceride glucose (TyG) index and the homeostatic model assessment of insulin resistance (HOMA-IR) in assessing insulin resistance (IR) in people living with HIV (PLWH). Additionally, we aimed to estimate a cut-off value for the TyG index in PLWH. Methods: This retrospective, observational study included medical records of patients diagnosed with HIV at Sakarya Training and Research Hospital from January 2019 to January 2024. Based on their HOMA-IR levels, PLWH patients were divided into 2 groups: Group A (patients without IR) and Group B (patients with IR). Results: In this study, insulin resistance was …
Shifting Sands: Unveiling The Changes In Respiratory Comorbidities And Fungal Pathogens In Saudi Arabia, Aiah M. Khateb, Fadwa S. Alofi, Mohammad A. Alturkostani, Abdullah Z. Almutairi
Shifting Sands: Unveiling The Changes In Respiratory Comorbidities And Fungal Pathogens In Saudi Arabia, Aiah M. Khateb, Fadwa S. Alofi, Mohammad A. Alturkostani, Abdullah Z. Almutairi
Saudi Medical Journal
Objectives: To investigate epidemiological changes in respiratory fungal infections (RFI), including fungal isolation and colonization, at one of the main centers in Medina. The incidence of RFI is rising due to an increase in the number of immunocompromised individuals, a higher prevalence of respiratory viral infections, and an aging population. Methods: A retrospective cross-sectional study was conducted by extracting data of patients with fungal-positive respiratory cultures from King Fahad Hospital (KFH), Al Madinah Al Munawwarah from 2013 to 2023. Results: A total of 352 episodes of fungal-positive cultures were identified in 79 patients, reflecting a 12-fold increase in RFI prevalence. …
Who Announces First Prequalification Of A Tuberculosis Diagnostic Test
Who Announces First Prequalification Of A Tuberculosis Diagnostic Test
Saudi Medical Journal
No abstract provided.
The Future Of Personalized Medicine In Saudi Arabia: Opportunities And Challenges, Wedad A. Mawkili
The Future Of Personalized Medicine In Saudi Arabia: Opportunities And Challenges, Wedad A. Mawkili
Saudi Medical Journal
Personalized medicine is a healthcare approach that designs treatment plans of each patient, considering genetic, environmental, and lifestyle factors. This model leverages genomic information, advanced diagnostics, and data analytics to predict disease risk, optimize prevention strategies, and provide customized treatments. In Saudi Arabia, personalized medicine is gaining momentum, driven by the country’s Vision 2030 initiative, which aims to transform the healthcare sector by integrating advanced medical technologies and improving healthcare delivery. The Kingdom has made significant strides in genomics and bioinformatics, with initiatives such as the Saudi Human Genome Program and advancements in institutions i.e., King Faisal Specialist Hospital and …
The Relationship Between Mothers With Careers In Higher Education And Child Development In Indonesia, Zakiyah Yasin, Ahmad Nawawi, Shrimarti R. Devy, Siti R. Nadhiroh
The Relationship Between Mothers With Careers In Higher Education And Child Development In Indonesia, Zakiyah Yasin, Ahmad Nawawi, Shrimarti R. Devy, Siti R. Nadhiroh
Saudi Medical Journal
Objectives: To identify the association of mothers with a career in higher educati--on and their children’s growth and development. Methods: This was an analytical study with a cross-sectional design carried out at Wiraraja University, Sumenep, Indonesia, from March to August 2023. The samples were female lecturers at Wiraraja University. A total of 107 mothers were selected using total sampling. The mother’s career was identified using a questionnaire and their child’s growth and development were measured using child development pre-screening questionnaire. This study used Spearman’s test data analysis. Results: The correlation coefficient was 0.512 indicating a moderately strong relationship between working …
Elevated Levels Of Cd56+ T Cells, Cd16+ Cd56+ T Cells, And Cd56dim Nk Cells In Herpes Simplex Virus Type 1 Seropositive Healthy Individuals, Mazen Almehmadi, Mamdouh Allahyani, Abdulelah Aljuaid, Meshari A. Alsuwat, Mustafa Halawi
Elevated Levels Of Cd56+ T Cells, Cd16+ Cd56+ T Cells, And Cd56dim Nk Cells In Herpes Simplex Virus Type 1 Seropositive Healthy Individuals, Mazen Almehmadi, Mamdouh Allahyani, Abdulelah Aljuaid, Meshari A. Alsuwat, Mustafa Halawi
Saudi Medical Journal
Objectives: To investigate the numbers of natural killer (NK) cells, CD56+ T-cells and CD56- T cells, and the levels ofCD16 in healthy individuals seropositive for herpes simplex virus Type 1 (HSV-1). Specifically, it seeks to measure the levels of these cells to learn about the possible immunological significance during HSV-1 seropositive status. Methods: This study employed a cross-sectional research design to examine the levels of CD56+ T-cells and CD16+ among individuals seropositive for herpes simplex virus type 1 (HSV-1) in Taif city. A total of 112 participants were enrolled, with HSV-1 serostatus determined via ELISA, and cellular evaluation conducted using …
Rising Epidemiological Trends In Prevalence And Mortality Of Mpox: Global Insights And Analysis, Muhammad Os. Meo, Muhammad Zs. Meo, Isra M. Khan, Muhammad As. Butt, Adnan M. Usmani, Sultan A. Meo
Rising Epidemiological Trends In Prevalence And Mortality Of Mpox: Global Insights And Analysis, Muhammad Os. Meo, Muhammad Zs. Meo, Isra M. Khan, Muhammad As. Butt, Adnan M. Usmani, Sultan A. Meo
Saudi Medical Journal
Objectives: To explore the global epidemiological trends in the prevalence and mortality due to mpox in various regions worldwide. Methods: In this cross-sectional study the data about mpox outbreak were recorded by the “World Health Organization, Centers for Disease Control and Prevention, and GSAID” from August 2023 to August 2024, analyzing the epidemiological trends from different countries worldwide. Results: The total number of mpox cases has reached 99,518 (95,196 cases from 115 countries that have not historically reported mpox; and 4,322 cases from 07 states that have traditionally reported mpox), from a total of 122 countries. The top 10 countries …
Comparing Tele-Pharmacy And Standard Clinic Follow-Up For Newly Initiated Warfarin Anticoagulation Therapy: A Retrospective Study, Sumaiah J. Alarfaj, Sara Alsulami, Ebtehaj Alashjaey, Reema Albulayhi, Faisal Alqarni, Abeer Alharbi
Comparing Tele-Pharmacy And Standard Clinic Follow-Up For Newly Initiated Warfarin Anticoagulation Therapy: A Retrospective Study, Sumaiah J. Alarfaj, Sara Alsulami, Ebtehaj Alashjaey, Reema Albulayhi, Faisal Alqarni, Abeer Alharbi
Saudi Medical Journal
ABSTRACT Objectives: To compare the effectiveness of providing telepharmacy anticoagulation to on-site clinics in achieving optimal outcomes for patients newly starting warfarin. Methods: This single-center retrospective cohort study included adult patients who started warfarin for the first time and were monitored by clinical pharmacists either on-site or via telepharmacy anticoagulation clinics between January 2017 and March 2024. The primary outcome is to compare the time in therapeutic range (TTR) between the 2 groups. The secondary outcome is the occurrence of anticoagulation therapy–related complications. Results: We included 191 patients, with 77 in the telepharmacy group and 114 in the on-site group. …
Assessing The Accuracy And Efficiency Of Chat Gpt-4 Omni (Gpt-4o) In Biomedical Statistics: Comparative Study With Traditional Tools, Anusha S. Meo, Narmeen Shaikh, Sultan A. Meo
Assessing The Accuracy And Efficiency Of Chat Gpt-4 Omni (Gpt-4o) In Biomedical Statistics: Comparative Study With Traditional Tools, Anusha S. Meo, Narmeen Shaikh, Sultan A. Meo
Saudi Medical Journal
ABSTRACT Objectives: To assess the accuracy of ChatGPT-4 Omni (GPT-4o) in biomedical statistics. The recent novel inauguration of Artificial Intelligence ChatGPT-Omni (GPT-4o), has emerged with the potential to analyze sophisticated and extensive data sets, challenging the expertise of statisticians using traditional statistical tools for data analysis. Methods: This study was performed in the Department of Physiology, College of Medicine, King Saud University, Riyadh, Saudi Arabia, in May 2024. Three datasets in a raw Excel file format were imported onto Statistical Package for the Social Sciences (SPSS) version 29 for data analysis. Based on this analysis, a script of 9 questions …
Characteristics And One-Year Outcomes Of Patients With Advanced Atrioventricular Block In Saudi Arabia: A Single-Center Retrospective Cohort Study, Wael A. Alqarawi, Abdulrahman S. Alarifi
Characteristics And One-Year Outcomes Of Patients With Advanced Atrioventricular Block In Saudi Arabia: A Single-Center Retrospective Cohort Study, Wael A. Alqarawi, Abdulrahman S. Alarifi
Saudi Medical Journal
Objectives: To report and describe the characteristics and outcomes of patients with advanced atrioventricular block (AVB) in Saudi Arabia. Methods: We included consecutive patients who underwent pacemaker implantation at King Khaled University Hospital, Riyadh, Saudi Arabia, for advanced AVB, which was defined as second degree type 2 AVB, third degree AVB, and symptomatic atrial fibrillation with slow ventricular response. The variable “young patient” was defined as age of 60 or less, based on guidelines recommending cardiac sarcoidosis (CS) evaluation at this age or younger. Results: Among 100 patients (median age: 71 males, 51%), 29 (29%) were young patients. Most patients …
The Association Of Liver Fibrosis And Chronic Kidney Disease In Patients With Metabolic Associated Fatty Liver Disease: A Cross-Sectional Study, Rehab Badawi, Sara Essam Hasby, Walaa Elkhalawany, Waleed Elrefaey, Nahla Ahmed Khalf, Hanaa Ibrahim Okda
The Association Of Liver Fibrosis And Chronic Kidney Disease In Patients With Metabolic Associated Fatty Liver Disease: A Cross-Sectional Study, Rehab Badawi, Sara Essam Hasby, Walaa Elkhalawany, Waleed Elrefaey, Nahla Ahmed Khalf, Hanaa Ibrahim Okda
Saudi Medical Journal
Objectives: To examine the relation between liver fibrosis and chronic kidney disease (CKD) in metabolic-associated fatty liver disease (MAFLD) patients and its risk factors. Methods: The current study was carried out at Tanta University Hospital, Tanta, Egypt, from May 2021 to January 2023 and included 84 MAFLD patients with CKD and 80 MAFLD patients without CKD. All participants had been examined by abdominal ultrasonography and transient elastography with controlled attenuation parameter. Results: Chronic kidney disease patients exhibited a greater incidence of fibrosis compared to patients without CKD (75.6% vs. 24.4%). Logistic analysis demonstrated that the presence of multiple health conditions, …
Global Strategic Preparedness And Response Plan Launched By Who To Contain Mpox Outbreak
Global Strategic Preparedness And Response Plan Launched By Who To Contain Mpox Outbreak
Saudi Medical Journal
No abstract provided.
In This Issuereview Articleoriginal Articlecase Report
In This Issuereview Articleoriginal Articlecase Report
Saudi Medical Journal
No abstract provided.
The Protagonist Of Contemporary And Emerging Nanotechnology-Based Theranostics And Therapeutic Approaches In Reshaping Intensive Care Unit, Ling Xie, Yun Chen
The Protagonist Of Contemporary And Emerging Nanotechnology-Based Theranostics And Therapeutic Approaches In Reshaping Intensive Care Unit, Ling Xie, Yun Chen
Saudi Medical Journal
To maintain a clean and hygienic environment in the intensive care unit (ICU) is crucial for ensuring patient safety, preventing infections, and reducing healthcare-associated complications. With the increasing prevalence of infections and the emergence of viral and bacterial resistance to standard antiseptics, there is a pressing need for innovative antiseptic solutions. Nanotechnology is increasingly being employed in medicine, particularly focusing on mitigating the activities of various pathogens, including those associated with hospital-acquired infections. This paper explores the current impact of nanotechnology, with a particular focus on bacterial infections and SARS-CoV-2, which significantly strain healthcare systems, and then discusses how nanotechnology …
Serological Markers Of Transfusion Transmissible Infections And Abo Blood Groups In Najran, Saudi Arabia, Ahmad A. Alshehri, Ahmad Adebayo Irekeola, Mohammed Merae Alshahrani, Saeed Ahmed Asiri, Banan F. Aboluluy, Abdulaziz Hassan Alhasaniah, Ibrahim Abdullah Almazni, Saleh A. Alshamrani, Abdullah J. Alshahrani, Ahmad M. Saif, Osman Ae. Elnoubi, Abdulrahim R. Hakami, Abdulrazzag Abdulaziz Othman, Mansor H. Almohi
Serological Markers Of Transfusion Transmissible Infections And Abo Blood Groups In Najran, Saudi Arabia, Ahmad A. Alshehri, Ahmad Adebayo Irekeola, Mohammed Merae Alshahrani, Saeed Ahmed Asiri, Banan F. Aboluluy, Abdulaziz Hassan Alhasaniah, Ibrahim Abdullah Almazni, Saleh A. Alshamrani, Abdullah J. Alshahrani, Ahmad M. Saif, Osman Ae. Elnoubi, Abdulrahim R. Hakami, Abdulrazzag Abdulaziz Othman, Mansor H. Almohi
Saudi Medical Journal
Objectives: To ascertain the prevalence of transfusion transmissible infections (TTIs) across diverse donor groups in the Najran province. Additionally, to establish a potential association between the development of TTI and the donors’ blood group, as determined by the ABO/Rh blood grouping system. Methods: Blood donation data of 4120 donors, spanning from January to December 2020, were retrospectively reviewed. The blood were screened for TTI markers, including hepatitis B surface antigen (HBsAg), anti-hepatitis B core (anti-HBc), anti-hepatitis C virus (anti-HCV), anti-human immunodeficiency viruses 1 and 2 (anti-HIV1&2), anti-human T-lymphotropic virus types 1 and 2 (anti-HTLV-1&2), and syphilis antigen. Results: Positive TTI …
Retrospective Analysis Of The Clinical Utility Of Multi-Cytokine Profiles In Smear-Negative Pulmonary Tuberculosis, Xuemei Li, Weidong Zhao, Hong Han, Zhi Yang, Fengqing Bi, Yingchun He
Retrospective Analysis Of The Clinical Utility Of Multi-Cytokine Profiles In Smear-Negative Pulmonary Tuberculosis, Xuemei Li, Weidong Zhao, Hong Han, Zhi Yang, Fengqing Bi, Yingchun He
Saudi Medical Journal
Objectives: To evaluate cytokine profiles and interferon-gamma release assay (IGRA) for their diagnostic capabilities in the differentiation of tuberculosis (TB) from non-TB conditions, as well as smear-negative pulmonary tuberculosis (SNPT) from smear-positive pulmonary tuberculosis (SPPT). Methods: A total of 125 participants were included, 77 of whom had TB and 48 who didn’t, and demographic, clinical, and laboratory data were collected, including cytokine levels and IGRA results. The TB patients were further divided into 2 subgroups: SNPT (n=42) and SPPT (n=35). Results: Compared to non-TB, the TB group had lower BMI, higher WBC, neutrophils, monocytes, ESR and CRP ( p <0.05). TB patients showed higher IL-2, IL-6, IFN-γ, IL-8 ( p <0.001) and higher IGRA positivity (88.3% versus [vs.] 29.2%, p <0.001). Between SNPT and SPPT, moderate effect sizes were observed for IFN-α, IL-2, IL-10, IL-8 (Cohen’s d 0.59-0.76), with lower IGRA positivity in SNPT (81.0% vs. 97.1%, p =0.015). ROC analysis indicated IFN-α, IL-2, IL-10, IL-8 had moderate accuracy for SNPT diagnosis (AUCs 0.668-0.734), and combining these improved accuracy (AUC 0.759, 80% sensitivity, 64.2% specificity). Conclusion: A multi-biomarker approach combining these cytokines demonstrates enhanced diagnostic accuracy for tuberculosis.
Childhood Vaccination Hesitancy In Saudi Arabia: Are We Still Facing A Problem?: A Narrative Review
Childhood Vaccination Hesitancy In Saudi Arabia: Are We Still Facing A Problem?: A Narrative Review
Saudi Medical Journal
Vaccination is a crucial public health intervention for infection prevention. Yet, vaccine hesitation has emerged as a pressing public health concern. The objective of this review is to identify the widespread and causes of vaccine hesitancy prevalance among parents of children in Saudi Arabia. A narrative review, surveying several databases, including PubMed, PubMed Central, Scopus, Google Scholar, and relevant regional journals. We selected studies related to vaccine hesitancy prevalence and causes after removing duplicates and screening for relevance and access to full text. A total of 18 articles met the final selection criteria. The prevalence of parental vaccination reluctance in …
Evaluation Of Candidemia Risk Factors And Candida Species Distribution In Intensive Care Units Among Patients With And Without Covid-19, Cemile Uyar, Emel Yıldız, Özlem Genç, Öznur Ak, Emel Koçak, Sevil Alkan, Canan Balcı, Pınar Korkmaz, Duru Mıstanoğlu Özatağ, Halil Aslan
Evaluation Of Candidemia Risk Factors And Candida Species Distribution In Intensive Care Units Among Patients With And Without Covid-19, Cemile Uyar, Emel Yıldız, Özlem Genç, Öznur Ak, Emel Koçak, Sevil Alkan, Canan Balcı, Pınar Korkmaz, Duru Mıstanoğlu Özatağ, Halil Aslan
Saudi Medical Journal
Objectives: To assess the risk variables related to the types of candidemia for each patient, who was admitted into the intensive care unit regardless of the patient with or without complete diagnosis of COVID-19, during the period of March 2019 to December 2022. Methods: The evaluation comparison of demographic and clinical data of COVID-19 positive and negative patients with candidemia confirmed in blood, 113 cases were assessed. Variables such as gender, age, age of hospitalization, history of hospitalization, concurrently infection, The acute physiology and chronic health evaluation-II scores, comorbidity checking, intubation, central venous catheter use, parenteral nutrition use, steroid use, …
Effect Of Cortisol And Glycosylated-Hemoglobin Levels On Mortality In Intensive Care Unit, Oznur Sen, Ugur Uzun, Nurdan Aydin, Isil Guldogan
Effect Of Cortisol And Glycosylated-Hemoglobin Levels On Mortality In Intensive Care Unit, Oznur Sen, Ugur Uzun, Nurdan Aydin, Isil Guldogan
Saudi Medical Journal
Objectives: To research the effects of blood cortisol and hemoglobinA1c (HBA1C) levels on mortality in patients admitted to the intensive care unit (ICU) and whether these factors could be used as reliable indicators for mortality risk assessment in these patients. Methods: After receiving approval from the ethics committee, 79 patients admitted to ICU were included in the study. From patient files, we collected data on demographics (age, gender), presence of diabetes mellitus, and levels of cortisol, HbA1C, glucose, and lactate measured during hospitalization, along with acute physiology and chronic health evaluation (APACHE) II scores calculated within the first 24 hours. …
Molecular Epidemiology And Molecular Typing Methods Of Acinetobacter Baumannii: An Updated Review, Razique Anwer
Molecular Epidemiology And Molecular Typing Methods Of Acinetobacter Baumannii: An Updated Review, Razique Anwer
Saudi Medical Journal
The aim of this study was to go through the molecular methods used for typing of carbapenem-resistant Acientobacter baumannii (CRAB) isolates for investigating the molecular epidemiology all over the world. Multiple typing techniques are required to understand the source and nature of outbreaks caused by Acientobacter baumannii ( A. baumannii ) and acquired resistance to antimicrobials. Nowadays, there is gradual shift from traditional typing methods to modern molecular methods to study molecular epidemiology and infection control. Molecular typing of A. baumannii strains has been revolutionized significantly in the last 2 decades. A few sequencing-based techniques have been proven as a …
Investigation Of Hematologic Findings Related To Brucellosis In Anatolian Region, Mehmet Çelik, Yusuf Arslan, Ertuğrul Topcu, Mustafa Serhat Şahinoğlu, Deniz Altındağ, Esra Gürbüz, Ebru Atalay, Sümeyye Kışlak Demircan, Salih Emre, Yasemin Kırık, Pınar Yürük Atasoy, Deniz Özer, Davut İpek, Ebru Doğan, Seval Bilgiç Atlı, Evrim Gülderen Kuşçu, Sevil Alkan, Yeliz Çiçek, Esra Yüksekkaya, Özlem Aldemir, Ahmet Şahin, Fatma Yekta Ürkmez, Sevda Özdemir Al, Riyad Boran, Serpil Oğuz Mızrakçı, Mehmet Reşat Ceylan, Hamza Erdoğdu, Süda Tekin
Investigation Of Hematologic Findings Related To Brucellosis In Anatolian Region, Mehmet Çelik, Yusuf Arslan, Ertuğrul Topcu, Mustafa Serhat Şahinoğlu, Deniz Altındağ, Esra Gürbüz, Ebru Atalay, Sümeyye Kışlak Demircan, Salih Emre, Yasemin Kırık, Pınar Yürük Atasoy, Deniz Özer, Davut İpek, Ebru Doğan, Seval Bilgiç Atlı, Evrim Gülderen Kuşçu, Sevil Alkan, Yeliz Çiçek, Esra Yüksekkaya, Özlem Aldemir, Ahmet Şahin, Fatma Yekta Ürkmez, Sevda Özdemir Al, Riyad Boran, Serpil Oğuz Mızrakçı, Mehmet Reşat Ceylan, Hamza Erdoğdu, Süda Tekin
Saudi Medical Journal
Objectives: To investigate the prevalence of hematologic findings and the relationship between hemogram parameters and brucellosis stages in patients. Methods: This multi-center study included patients older than 16 years of age who were followed up with a diagnosis of brucellosis. Patients’ results, including white blood cell, hemoglobin, neutrophil, lymphocyte, monocyte, mean platelet volume, platelet and eosinophil counts were analyzed at the initial diagnosis. Results: In this study 51.3% of the patients diagnosed with brucellosis were male. The age median was 45 years for female and 41 years for male. A total of 55.1% of the patients had acute brucellosis, 28.2% …
Association Of Abo, Rh-D And Kell Blood Groups With Transfusion Transmitted Infections Among Blood Donors From The Asir Region, Saudi Arabia: A Retrospective Observational Study, Ahmad A. Shaikh, Hassan M. Alqasem, Yahya A. Alshubruqi, Sultan Z. Alasmari, Mohammed H. Makkawi
Association Of Abo, Rh-D And Kell Blood Groups With Transfusion Transmitted Infections Among Blood Donors From The Asir Region, Saudi Arabia: A Retrospective Observational Study, Ahmad A. Shaikh, Hassan M. Alqasem, Yahya A. Alshubruqi, Sultan Z. Alasmari, Mohammed H. Makkawi
Saudi Medical Journal
Objectives: To evaluate the association between transfusion-transmitted infections (TTIs) and ABO, Rh-D, and Kell blood systems among blood donors. Methods: This was a retrospective study of 10,095 donors who visited the Blood Bank at Asir Hospital, Abha, Saudi Arabia. Data including demographic information, ABO, Rh-D, and Kell blood groups, and serological and molecular test results of TTIs (the TTIs were obtained from each donor’s records). Chi-squared and Fisher’s exact tests were employed to establish possible associations between blood groups and TTIs. Results: The prevalence rate of TTIs among donors was 6.3%, with HBcAb (70%) being the most prevalent biomarker among …