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Taking The Long View: A Case Study Of E-Book Usage At A Comprehensive Research University, Edward F. Lener, Mitch Moulton Sep 2018

Taking The Long View: A Case Study Of E-Book Usage At A Comprehensive Research University, Edward F. Lener, Mitch Moulton

Charleston Library Conference

The University Libraries at Virginia Tech made their first major acquisition of e-books in 2008 with a purchase of new e-book collections from Springer. While the business relationship has evolved over time, it has continued forward to the present day. Currently, the library’s online holdings include most of the frontlist subject collections available from what is now Springer Nature, as well as the Springer book series and the Springer Book Archives. In all, the University Libraries make over 120,000 e-books available to patrons through the SpringerLink platform. The cumulative usage of this material represents over two million chapter downloads by …


De Novo Sequence And Copy Number Variants Are Strongly Associated With Tourette Disorder And Implicate Cell Polarity In Pathogenesis, Sheng Wang, Jeffrey D. Mandell, Yogesh Kumar, Nawei Sun, Montana T. Morris, Juan Arbelaez, Cara Nasello, Shan Dong, Clif Duhn, Xin Zhao, Zhiyu Yang, Shanmukha S. Padmanabhuni, Dongmei Yu, Robert A. King, Andrea Dietrich, Najah Khalifa, Niklas Dahl, Alden Y. Huang, Benjamin M. Neale, Giovanni Coppola, Carol A. Mathews, Jeremiah M. Scharf, Tourette International Collaborative Genetics Study (Tic Genetics), Tourette Syndrome Genetics Southern And Eastern Europe Initiative (Tsgenesee), Tourette Association Of America International Consortium For Genetics (Taaicg), Thomas V. Fernandez, Joseph D. Buxbaum, Silvia De Rubeus, Dorothy E. Grice, Jinchuan Xing, Gary A. Heiman, Jay A. Tischfield, Peristera Paschou, A Jeremy Wilsey, Matthew W. State Sep 2018

De Novo Sequence And Copy Number Variants Are Strongly Associated With Tourette Disorder And Implicate Cell Polarity In Pathogenesis, Sheng Wang, Jeffrey D. Mandell, Yogesh Kumar, Nawei Sun, Montana T. Morris, Juan Arbelaez, Cara Nasello, Shan Dong, Clif Duhn, Xin Zhao, Zhiyu Yang, Shanmukha S. Padmanabhuni, Dongmei Yu, Robert A. King, Andrea Dietrich, Najah Khalifa, Niklas Dahl, Alden Y. Huang, Benjamin M. Neale, Giovanni Coppola, Carol A. Mathews, Jeremiah M. Scharf, Tourette International Collaborative Genetics Study (Tic Genetics), Tourette Syndrome Genetics Southern And Eastern Europe Initiative (Tsgenesee), Tourette Association Of America International Consortium For Genetics (Taaicg), Thomas V. Fernandez, Joseph D. Buxbaum, Silvia De Rubeus, Dorothy E. Grice, Jinchuan Xing, Gary A. Heiman, Jay A. Tischfield, Peristera Paschou, A Jeremy Wilsey, Matthew W. State

Department of Biological Sciences Faculty Publications

We previously established the contribution of de novo damaging sequence variants to Tourette disorder (TD) through whole-exome sequencing of 511 trios. Here, we sequence an additional 291 TD trios and analyze the combined set of 802 trios. We observe an overrepresentation of de novo damaging variants in simplex, but not multiplex, families; we identify a high-confidence TD risk gene, CELSR3 (cadherin EGF LAG seven-pass G-type receptor 3); we find that the genes mutated in TD patients are enriched for those related to cell polarity, suggesting a common pathway underlying pathobiology; and we confirm a statistically significant excess of de novo …


Supplemental Materials: Scalability Assessment Tools And Resources, United States Agency For International Development/Management Systems International, International Maize And Wheat Improvement Center, International Fund For Agricultural Development Sep 2018

Supplemental Materials: Scalability Assessment Tools And Resources, United States Agency For International Development/Management Systems International, International Maize And Wheat Improvement Center, International Fund For Agricultural Development

Scale Up Conference

INCLUDED:

USAID/MSI (United States Agency for International Development/Management Systems International), Agricultural Scalability Assessment Tool (ASAT)

  • Step 1: Decision tree
  • Step 2: Evaluate scalability using a worksheet/matrix
  • Detailed ASAT criteria

PPP Lab Food & Water and CIMMYT (International Maize and Wheat Improvement Center)

  • The Scaling Scan – A practical tool to determine strengths and weaknesses of a scaling ambition

IFAD (International Fund for Agricultural Development)

  • Questions on scaling up to be considered when designing an IFAD project to reach greater impact
  • The phases of scaling up


Tesselations And Percolations In Topologically Interlocked Stereotomic Material Systems, Andrew Williams, Thomas Siegmund Sep 2018

Tesselations And Percolations In Topologically Interlocked Stereotomic Material Systems, Andrew Williams, Thomas Siegmund

IUTAM Symposium Architectured Materials Mechanics

No abstract provided.


Emergent Wave Phenomena In Coupled Elastic Bars: From Extreme Attenuation To Realization Of Elastodynamic Switches, Qianli Chen, Ahmed Elbanna Sep 2018

Emergent Wave Phenomena In Coupled Elastic Bars: From Extreme Attenuation To Realization Of Elastodynamic Switches, Qianli Chen, Ahmed Elbanna

IUTAM Symposium Architectured Materials Mechanics

No abstract provided.


Fiber Reorientation Behavior Of Bioinspired Bouligand Architectures With Functional Graded Fiber Orientation, Di Wang, Alireza Zaheri, Benjamin Russell, Pablo Zavattieri Sep 2018

Fiber Reorientation Behavior Of Bioinspired Bouligand Architectures With Functional Graded Fiber Orientation, Di Wang, Alireza Zaheri, Benjamin Russell, Pablo Zavattieri

IUTAM Symposium Architectured Materials Mechanics

No abstract provided.


Topologically Interlocked Material Systems: From A Material Design Concept To Properties, Thomas Siegmund Sep 2018

Topologically Interlocked Material Systems: From A Material Design Concept To Properties, Thomas Siegmund

IUTAM Symposium Architectured Materials Mechanics

No abstract provided.


Extremal Material And Structure Design By Topology Optimization, Ole Sigmund, Jeroen Groen Sep 2018

Extremal Material And Structure Design By Topology Optimization, Ole Sigmund, Jeroen Groen

IUTAM Symposium Architectured Materials Mechanics

No abstract provided.


Energy Harvesting In Phase Transforming Materials, Aman Thakkar, Nilesh Mankame, Pablo Zavattieri, Andres F. Sep 2018

Energy Harvesting In Phase Transforming Materials, Aman Thakkar, Nilesh Mankame, Pablo Zavattieri, Andres F.

IUTAM Symposium Architectured Materials Mechanics

No abstract provided.


Design And Performance Of Periodic Trusses, Frank Zok, Matthew Begley, Ryan Latture Sep 2018

Design And Performance Of Periodic Trusses, Frank Zok, Matthew Begley, Ryan Latture

IUTAM Symposium Architectured Materials Mechanics

No abstract provided.


Lattice Structures And Strength Optimization, Vince Vernacchio, Thomas Siegmund Sep 2018

Lattice Structures And Strength Optimization, Vince Vernacchio, Thomas Siegmund

IUTAM Symposium Architectured Materials Mechanics

No abstract provided.


Intermittent Interfaces: Bioinspired Strategies Towards Material Resilience, H.Daniel Wagner, Israel Greenfeld, Wenyong Zhang, Xiaomeng Sui Sep 2018

Intermittent Interfaces: Bioinspired Strategies Towards Material Resilience, H.Daniel Wagner, Israel Greenfeld, Wenyong Zhang, Xiaomeng Sui

IUTAM Symposium Architectured Materials Mechanics

No abstract provided.


Flexoelectricity-Based Electromechanical Metamaterials, A. Mocci, D. Codony, A. Abdollahi, Irene Arias Sep 2018

Flexoelectricity-Based Electromechanical Metamaterials, A. Mocci, D. Codony, A. Abdollahi, Irene Arias

IUTAM Symposium Architectured Materials Mechanics

No abstract provided.


Extending Origami: Crease Pre-Stressing For Functional Adaptation, Andres Arrieta, Jakob Faber, Katherine Riley, André Studart Sep 2018

Extending Origami: Crease Pre-Stressing For Functional Adaptation, Andres Arrieta, Jakob Faber, Katherine Riley, André Studart

IUTAM Symposium Architectured Materials Mechanics

No abstract provided.


Bcc Metamaterials Composed Of Tapered Beams: Stiffness And Energy Absorption, Thomas Tancogne-Dejean, Dirk Mohr Sep 2018

Bcc Metamaterials Composed Of Tapered Beams: Stiffness And Energy Absorption, Thomas Tancogne-Dejean, Dirk Mohr

IUTAM Symposium Architectured Materials Mechanics

No abstract provided.


Exploiting Auxetics To Design Composite Materials With Enhanced Mechanical Performance, Tiantian Li, Lifeng Wang Sep 2018

Exploiting Auxetics To Design Composite Materials With Enhanced Mechanical Performance, Tiantian Li, Lifeng Wang

IUTAM Symposium Architectured Materials Mechanics

No abstract provided.


Exploring Material Property Space Using Bioinspiration And Architecture, Francois Barthelat Sep 2018

Exploring Material Property Space Using Bioinspiration And Architecture, Francois Barthelat

IUTAM Symposium Architectured Materials Mechanics

No abstract provided.


Architecture And Internal Material Length Scale: Fatigue Crack Growth Across Weak Interfaces, Josh Pribe, Thomas Siegmund Sep 2018

Architecture And Internal Material Length Scale: Fatigue Crack Growth Across Weak Interfaces, Josh Pribe, Thomas Siegmund

IUTAM Symposium Architectured Materials Mechanics

No abstract provided.


Mechanical Instability-Driven Architecturing Of Atomically-Thin Materials, Sungwoo Nam Sep 2018

Mechanical Instability-Driven Architecturing Of Atomically-Thin Materials, Sungwoo Nam

IUTAM Symposium Architectured Materials Mechanics

No abstract provided.


A Numerical Simulation Capability For Electroelastic Wave Propagation In Dielectric Elastomer Composites: Application To Tunable Soft Phononic Crystals, Michael Jandron, David Henann Sep 2018

A Numerical Simulation Capability For Electroelastic Wave Propagation In Dielectric Elastomer Composites: Application To Tunable Soft Phononic Crystals, Michael Jandron, David Henann

IUTAM Symposium Architectured Materials Mechanics

No abstract provided.


Acoustic Band Gaps, Sound Attenuation, And Elastic Stiffness Of Pmma Cellular Materials Based On Triply Periodic Minimal Surfaces, Diab Abueidda, Iwona Jasiuk, Nahil Sobh Sep 2018

Acoustic Band Gaps, Sound Attenuation, And Elastic Stiffness Of Pmma Cellular Materials Based On Triply Periodic Minimal Surfaces, Diab Abueidda, Iwona Jasiuk, Nahil Sobh

IUTAM Symposium Architectured Materials Mechanics

No abstract provided.


Fishnet Statistics For Failure Probability Of Nacreous Staggered Laminar Materials, Zdeněk Bažant, Wen Luo Sep 2018

Fishnet Statistics For Failure Probability Of Nacreous Staggered Laminar Materials, Zdeněk Bažant, Wen Luo

IUTAM Symposium Architectured Materials Mechanics

No abstract provided.


Architected Materials: From Reconfigurability To Nonlinear Waves, Katia Bertoldi Sep 2018

Architected Materials: From Reconfigurability To Nonlinear Waves, Katia Bertoldi

IUTAM Symposium Architectured Materials Mechanics

No abstract provided.


Non-Reciprocity In Mechanical Metamaterials, Corentin Coulais Sep 2018

Non-Reciprocity In Mechanical Metamaterials, Corentin Coulais

IUTAM Symposium Architectured Materials Mechanics

No abstract provided.


Fracture Toughness Of Hierarchical, Low Density Architected Metamaterials, H. Cui, M.R. O'Masta, V.S. Deshpande, Xiaoyu Zheng Sep 2018

Fracture Toughness Of Hierarchical, Low Density Architected Metamaterials, H. Cui, M.R. O'Masta, V.S. Deshpande, Xiaoyu Zheng

IUTAM Symposium Architectured Materials Mechanics

No abstract provided.


Piezoelectric Polymer Thin Films With Architected Cuts, Lichen Fang, Jing Li, Zeyu Zhu, Santiago Orrego Sep 2018

Piezoelectric Polymer Thin Films With Architected Cuts, Lichen Fang, Jing Li, Zeyu Zhu, Santiago Orrego

IUTAM Symposium Architectured Materials Mechanics

No abstract provided.


Thermally Actuated Planar Lattices With High Fractal Stiffness, Amr Farag, Hang Xu, Damiano Pasini Sep 2018

Thermally Actuated Planar Lattices With High Fractal Stiffness, Amr Farag, Hang Xu, Damiano Pasini

IUTAM Symposium Architectured Materials Mechanics

No abstract provided.


Architected Cardiovascular Implants For Accommodating Growth, Sung Hoo Kang, Galip Erol, Emilio Bachtiar, Azra Horowitz Sep 2018

Architected Cardiovascular Implants For Accommodating Growth, Sung Hoo Kang, Galip Erol, Emilio Bachtiar, Azra Horowitz

IUTAM Symposium Architectured Materials Mechanics

No abstract provided.


Assembled Composite Lattice Structures: Towards Ideal Performance In Large-Scale Applications, Christine Gregg, Benjamin Jenett, Kenneth Cheung Sep 2018

Assembled Composite Lattice Structures: Towards Ideal Performance In Large-Scale Applications, Christine Gregg, Benjamin Jenett, Kenneth Cheung

IUTAM Symposium Architectured Materials Mechanics

No abstract provided.


Topology Matters: Expanding The Design Space Of Lightweight Mechanical Metamaterials, Julian Rimoli, Hossein Salahshoor, Raj-Kumar Pal Sep 2018

Topology Matters: Expanding The Design Space Of Lightweight Mechanical Metamaterials, Julian Rimoli, Hossein Salahshoor, Raj-Kumar Pal

IUTAM Symposium Architectured Materials Mechanics

No abstract provided.