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Assessing The Preparedness Of The Veterinary Profession To Communicate With Limited English Proficient Spanish-Speaking Pet Owners, Ruth Ellen Landau

Open Access Dissertations

The purpose of the present study was to assess the preparedness of the veterinary profession to communicate with limited English proficient Spanish-speaking pet owners (LEP SSPOs). Results of surveys with 393 Latino pet owners, 383 small animal veterinarians and staff, and over 2000 veterinary students indicate that interaction between veterinary professionals and LEP SSPOs is not a rare occurrence: Veterinarians in states with large established or fast-growing Latino communities are seeing LEP SSPOs and their pets on a regular basis: 89% of veterinarians have LEP Spanish-speaking clients, over half of these practitioners are seeing LEP SSPOs weekly, and over half …

Generation And Statistical Modeling Of Active Protein Chimeras: A Sequence Based Approach, Nicholas Fico

Open Access Dissertations

Generation of active protein chimeras is a valuable tool to probe the functional space of proteins. Statistical modeling is the next logical step, allowing us to build a model of gene fragment replaceability between species. In this thesis I begin to develop the statistical tools that are needed to systematically describe combinatorial protein libraries. I present three sets of diverse chimeric protein libraries developed using sequence information. The statistical model of the human N-Ras and human K-Ras-4B genes reveal a set previously unidetifed surface residues on the N-Ras G-Domain that may be involved in cellular localization. Statistical modeling of a …

Hybrid And Smart Topologically Interlocking Materials, Somesh Khandelwal

Open Access Dissertations

This thesis explores the mechanical properties of a new class of multifunctional architectured materials, Topologically Interlocking Materials (TIMs). These materials are created as an assembly of unit elements arranged in an interlocking pattern such that the load transfer between unit elements occurs by contact only. In the absence of adhesive interaction, the tensile component of the load is carried by complementary tensile elements in the form of external constraints or integrated filaments. By virtue of the bottom up design used in creating these materials, their mechanical properties are influenced by a number of controllable parameters including shape, confinement force, scale, …

Multiscale Simulation Of Thermocline Energy Storage For Concentrating Solar Power, Scott Michael Flueckiger

Open Access Dissertations

Concentrating solar power (CSP) is a renewable and demonstrated technology for large-scale power generation but requires multiple engineering advancements to achieve grid parity with conventional fossil fuels. Part of this advancement includes novel and inexpensive thermal energy systems to decouple daily power production from intermittent solar collection. Dual-media thermocline tanks, composed of molten salt and solid rock filler, offer low-cost storage capability but the concept has experienced limited deployment in CSP plants due to unresolved concerns about long-term thermal and structural stability. The main objective of the present work is to advance the understanding of thermocline storage design and operation …

Efficient Spectral-Element Methods For Acoustic Scattering And Related Problems, Ying He

Open Access Dissertations

This dissertation focuses on the development of high-order numerical methods for acoustic and electromagnetic scattering problems, and nonlinear fluid-structure interaction problems.

For the scattering problems, two cases are considered: 1) the scattering from a doubly layered periodic structure; and 2) the scattering from doubly layered, unbounded rough surface. For both cases, we first apply the transformed field expansion (TFE) method to reduce the two-dimensional Helmholtz equation with complex scattering surface into a successive sequence of the transmission problems with a plane interface. Then, we use Fourier-Spectral method in the periodic structure problem and Hermite-Spectral method in the unbounded rough surface …

The Application And Analysis Of Automated Triangulation Of Video Imagery By Successive Relative Orientation, Jae Sung Kim

Open Access Dissertations

The purpose of this thesis is the analysis and evaluation of methods to orient a strip of images using an automated approach. Automatic orientation of strips of video frame imagery would facilitate the construction of three dimensional models with less demand on a human operator for tedious measurement. Often one has no control points, so only relative orientation is possible. The relative orientation process gives camera parameters such as attitudes and selected baseline components and it can be implemented by using either collinearity or coplanarity equations. To automate the point selection, the pass and/or tie points were detected by the …

Using X-Ray Imaging Techniques To Determine Density Of Foods, Shivangi Mohan Kelkar

Open Access Dissertations

Density depends on the experimental technique and structural properties of food. True, apparent and bulk are different types of densities. For porous foods such as baked food products and complex food systems, accurate measurement of density is challenging. Empirical correlations dependent on composition and temperature exist to calculate true density. Thus if composition and apparent density are known, porosity can be calculated, porosity = [1 - (apparent density/ true density)]. Various non-destructive diagnostic tools have been employed to study food microstructure. Among these, computed tomography (CT) and digital radiography (DR) utilizing x-ray imaging showed greater capability for evaluation of food …

Peridynamic Modeling Of Coupled Mechanical Deformations And Transient Flow In Unsaturated Soils, Rami Jabakhanji

Open Access Dissertations

A coupled peridynamic model for mechanical deformations and transient moisture flow in unsaturated soils is developed. The model is capable of simulating the emergence and evolution of cracks triggered by volumetric strains in the soil which are associated with changes in moisture content. The development of our model is motivated by the need for a tool to analyze and evaluate the impact of dessication cracks on the movement of moisture and the mechanical properties of soils at the field scale. The model is based on the peridynamic reformulation of elasticity proposed by Silling for simulating the deformation of bodies with …

Developing A Drug Delivery System For Treatment Of Vocal Fold Scarring, Aaron Michael Kosinski

Open Access Dissertations

Vocal fold scarring is an affliction that results in the formation of a disorganized and stiff extracellular matrix (ECM) with abnormal ECM component densities & structures including a significant increase in collagen deposition. It is caused by improper healing post injury and results in profound changes in the biomechanical properties of the vocal folds impairing their ability to generate a normal mucosal wave during phonation.

Finding an effective treatment for vocal fold scarring has been elusive. Currently, treatments seek temporary solutions that correct glottal incompetence and reduce stiffness caused by the scar through the augmentation of the vocal folds using …

Fluorous- Phase Synthesis Of Heparan Sulfate Disaccharides & Low-Molecular Weight Additives For Enhancing The Performance Of Lithium-Ion Batteries., Matthew Daniel Casselman

Open Access Dissertations

Heparan sulfate is a complex cell-surface proteoglycan that serves many important roles in biology, such as growth and development, immune response and pathogenesis. Heparan sulfate is structurally heterogeneous due to the variable post- glycosylation modifications, particularly the generation of diverse sets of sulfate esters (sulfoforms) for any given disaccharide unit. In order to establish useful relationships between heparan sulfate structure and biological activity, a set of well-defined sulfoforms is necessary to support binding affinity screening. In this thesis, we describe the generation of diverse sulfoforms from heparan disaccharides using a fluorous tag to facilitate purification of highly charged intermediates, and …

Examining Teachers' Perspectives On An Implementation Of Elementary Engineering Teacher Professional Development, Nikki Kim Boots

Open Access Dissertations

The emphasis on engaging young learners in science, technology, engineering, and math (STEM) professions is driving calls for educational reform. One movement that is gaining momentum is exposing K-12 learners to engineering. With the advent of the Next Generation Science Standards (2012b), engineering is being more formally integrated into standards for the K-12 level. As a result, in-service elementary teachers will need to become familiar with the core concepts of engineering to effectively teach aspects of the subject in their classrooms. Elementary engineering teacher professional development (EETPD) has been identified as a method to disseminate engineering content knowledge to elementary …

Multiscale Modeling Of The Hierarchical Structure Of Cellulose Nanocrystals, Fernando Luis Dri

Open Access Dissertations

Cellulose constitutes the most abundant renewable polymeric resource available today. It considered an almost inexhaustible source of raw material, and holds great promise in meeting increasing demands for environmentally friendly and biocompatible products. Key future applications are currently under development for the automotive, aerospace and textile industries. When cellulose fibers are subjected to acid hydrolysis, the fibers yield rod-like, highly crystalline residues called cellulose nanocrystals (CNCs). These particles show remarkable mechanical and chemical properties (e.g. Young Modulus ~200 GPa) within the range of other synthetically-developed reinforcement materials. Critical to the design of these materials are fundamental material properties, many of …

Educational Standards, Teacher Preparation, And Metacognition Instruction For Elementary Students: Studies In Pre-College Engineering Education, Ronald Lee Carr

Open Access Dissertations

This dissertation is a compilation of three separate works representing a wide range of issues related to pre-college engineering. Each work addresses multiple levels of concern for educators from national policy to specific classroom intervention. Although presenting different styles of writing - due to different journals requirements - and various methods of research, all purpose to further research and instruction in pre-college engineering.

The research detailed in these papers has been inspired by the current STEM (science, technology, engineering, and mathematics) education movement and in particular, by the National Academy of Engineering's leadership in promoting the integration of engineering into …

Nanoscale Semiconductor Materials And Devices Employing Hybrid 1d And 2d Structures For Tunable Electronic And Photonic Applications, Suprem Ranjan Das

Open Access Dissertations

Das, Suprem R. Ph.D., Purdue University, December 2013. Nanoscale Semiconductor Materials and Devices employing Hybrid 1D and 2D structures for Tunable Electronic and Photonic Applications. Major Professor: Dr. David B. Janes.

Continued miniaturization of microelectronic devices over past decades has brought the device feature size towards the physical limit. Likewise, enormous `waste energy' in the form of self-heating in almost all of the electronic and optoelectronic devices needs an `energy-efficient low power' and `high performance' material as well as device with alternate geometry. III-V semiconductors are proven to be one of the alternate systems of materials for various applications including …

Measuring And Modeling The Response Characteristics Of The Environmental Phosphate Transducer In Escherichia Coli, Chetan Sood

Open Access Dissertations

The PhoR/PhoB two-component system in Escherichia coli is a biological transducer that senses the limitation of environmental inorganic orthophosphate, the bacteria's preferred source of the essential nutrient phosphate, and transmits that information to the interior of the cell initiating a response that mitigates phosphate starvation. In the first part of this study, we present and apply a fluorescence microscopy technique to measure, in vivo, the dynamic response characteristics of the transducer with single-cell resolution. We report that the transience in the PhoR/PhoB TCS response is consistent with the transducer having a threshold sensitivity to the concentration of environmental phosphate, …

Moocs Comparison And Implications For Purdue Nanohub-U Moocs, Wei Zakharov

Teaching and Learning Technologies Presentations

A massive open online course (MOOC) is an online course aiming at large-scale participation and open access via the web. Currently there are three main MOOCs providers: i.e. Udacity, Coursera, and edX. This presentation compared these providers in terms of their technical features and business models. On the other hand, the author presented how Purdue NanoHUB-U designed and developed MOOCs.

Improving Understanding Of Pre-Service Teacher Experience With Technology Integration., Christopher Mong

Teaching and Learning Technologies Publications

Pre-service teachers develop technology competency during their tenure in the college classroom. These stages coincide with Bloom's Revised Taxonomy and offer the opportunity to learn and model technology integration. 656 pre-service education students from five universities across the United States completed a qualitative survey aimed at identifying how they perceived technology integration throughout their teacher education program. Three themes, corresponding to Bloom's Revised Taxonomy, were identified; 1) pre-service teachers first identify and understand technology as a tool, 2) pre-service teachers apply technology and analyze the process of integration, and 3) overall, pre-service teachers do not evaluate and create technology integration …

Dil Symposium Day 2 Keynote: Engage In Culture Change: Fundamentals For Working In A Data Centric World, Viv Hutchison

Data Information Literacy Symposium

No abstract provided.

Dil Symposium Program Development Exercise: Social Sciences, Jake Carlson, Camille Andrews, Marianne S. Bracke, Michael Fosmire, Jon Jeffryes, Lisa Johnston, Megan R. Sapp Nelson, Dean Walton, Brian Westra, Sarah J. Wright

Data Information Literacy Symposium

No abstract provided.

Integrating Data Management Literacies With Data Visualization Instruction A One-Shot Workshop, Stacy Konkiel, Brianna Marshall, David Polley

Data Information Literacy Symposium

This poster describes a drop-in data management and visualization workshop under development. The workshop, scheduled for October 2013, will be aimed at graduate student researchers but open to all. The authors have mapped the core competencies for data information literacy outlined in "Determining Data Information Literacy Needs: A Study of Students and Research Faculty" (2011) with the workshop learning outcomes. Workshop planning considerations, content, and problems faced are described below. While this poster describes a workshop being developed at Indiana University, the authors hope this model will prove informative for other institutions looking to create similar workshops pairing data management …

Assessing The Need For Digital Information Literacy (Dil) For Graduate Students At The University Of Notre Dame, Mandy Havert, Parker Ladwig

Data Information Literacy Symposium

No abstract provided.

Desorption Electrospray Ionization Mass Spectrometry Reveals Lipid Metabolism Of Individual Oocytes And Embryos., Andrés Felipe González-Serrano, Valentina Pirro, Christina R. Ferreira, Paolo Oliveri, Livia S. Eberlin, Julia Heinzmann, Andrea Lucas-Hahn, Heiner Niemann, Robert Graham Cooks

Department of Chemistry Faculty Publications

Alteration of maternal lipid metabolism early in development has been shown to trigger obesity, insulin resistance, type 2 diabetes and cardiovascular diseases later in life in humans and animal models. Here, we set out to determine (i) lipid composition dynamics in single oocytes and preimplantation embryos by high mass resolution desorption electrospray ionization mass spectrometry (DESI-MS), using the bovine species as biological model, (ii) the metabolically most relevant lipid compounds by multivariate data analysis and (iii) lipid upstream metabolism by quantitative real-time PCR (qRT-PCR) analysis of several target genes (ACAT1, CPT 1b, FASN, SREBP1 and SCAP). Bovine oocytes and blastocysts …

The Role Of Microstructure Refinement On The Impact Ignition And Combustion Behavior Of Mechanically Activated Ni/Al Reactive Composites, B A. Mason, Lori J. Groven, Steven F. Son

Purdue Energetics Research Center Articles

Metal-based reactive composites have great potential as energetic materials due to their high energy densities and potential uses as structural energetic materials and enhanced blast materials however these materials can be difficult to ignite with typical particle size ranges. Recent work has shown that mechanical activation of reactive powders increases their ignition sensitivity, yet it is not fully understood how the role of microstructure refinement due to the duration of mechanical activation will influence the impact ignition and combustion behavior of these materials. In this work, impact ignition and combustion behavior of compacted mechanically activated Ni/Al reactive powder were studied …

Correlating The Purdue Spatial Visualization Test With The Wonderlic Personnel Test For American Football Players, Karthik Sukumar

Department of Computer Graphics Technology Degree Theses

This research study aims to find the relationship between the scores for the Purdue Spatial Visualization test (PSVT) and the Wonderlic Personnel test (WPT) for American collegiate football players. Fifty-five collegiate football players took part in the study by attempting the PSVT and the WPT. The scores on these tests were compared to find if there existed a correlation between the scores on both these tests. The results showed that the scores on both these tests had a significant correlation with respect to each other. But, the group that took the WPT before the PSVT showed a lower correlation between …

A Neutralizing Monoclonal Antibody Targeting The Acid-Sensitive Region In Chikungunya Virus E2 Protects From Disease., Suganya Selvarajah, Nicole R. Sexton, Kristen M. Kahle, Rachel H. Fong, Kimberly-Anne Mattia, Joy Gardner, Kai Lu, Nathan M. Liss, Beatriz Salvador, David F. Tucker, Trevor Barnes, Manu Mabila, Xiangdong Zhou, Giada Rossini, Joseph B. Rucker, David Avram Sanders, Andreas Suhrbier, Vittorio Sambri, Alain Michault, Marcus O. Muench, Benjamin J. Doranz, Graham Simmons

Department of Biological Sciences Faculty Publications

The mosquito-borne alphavirus, chikungunya virus (CHIKV), has recently reemerged, producing the largest epidemic ever recorded for this virus, with up to 6.5 million cases of acute and chronic rheumatic disease. There are currently no licensed vaccines for CHIKV and current anti-inflammatory drug treatment is often inadequate. Here we describe the isolation and characterization of two human monoclonal antibodies, C9 and E8, from CHIKV infected and recovered individuals. C9 was determined to be a potent virus neutralizing antibody and a biosensor antibody binding study demonstrated it recognized residues on intact CHIKV VLPs. Shotgun mutagenesis alanine scanning of 98 percent of the …

Improving Problem-Based Learning In Creative Communities Through Effective Group Evaluation, Richard E. West, Greg S. Williams, David D. Williams

Interdisciplinary Journal of Problem-Based Learning

In this case study, we researched one cohort from the Center for Animation, a higher education teaching environment that has successfully fostered group creativity and learning outcomes through problem-based learning. Through live and videotaped observations of the interactions of this community over 18 months, in addition to focused interviews with nine key community leaders, we considered the evaluative culture and actions of this community, and how these evaluative practices improved their creative problem solving. We describe their evaluation practices in the context of principles derived from the Joint Committees’ Evaluation Standards (Yarbrough, Shulha, Hopson, & Caruthers, 2011), which are well-respected …

Perspectives On Literary Reading And Book Culture, Geert Vandermeersche, Ronald Soetaert

CLCWeb: Comparative Literature and Culture

In their article "Perspectives on Literary Reading and Book Culture" Geert Vandermeersche and Ronald Soetaert provide a narrative framework for analyzing literary scholars' argumentation in the debate on literature and the humanities. Starting from MacIntyre's narrative description of epistemic "crises" they analyze the stories authors construct and the positions they take and ascribe to others within larger developing (grand) narratives on the value and function of literary reading. Both traditional narratives and new alternative (i.e., enlarged) narratives are discussed in how they set up and frame the argument and how they create dichotomies.

Reading, Literacy, And Education, Mikko Lehtonen

CLCWeb: Comparative Literature and Culture

In his article "Reading, Literacy, and Education" Mikko Lehtonen outlines a contextual approach to literacy. He asks how the changing relations of culture and economy, transformation of nation states and national cultures and changing notions concerning affect and cognition, transform notions of literacy and reading. Relying on the results of a recent Finnish research project on new reading communities and new ways of reading, Lehtonen highlights substantial continuities in the reading habits of the so called Google generation when compared to other generations of readers. Print media is not, however, connected self-evidently to cognitive reading among the said generation. Lehtonen …

“Seeing, Seeing, Seeing”: Deafness, Knowledge, And Subjectivity In Elizabeth Bowen, Maren Linett

Department of English Faculty Publications

In What is Posthumanism, Cary Wolfe enlists Temple Grandin’s account of her autism to critique reductive ideas of subjectivity. He quotes Oliver Sacks’s comment that Grandin’s first book was “unthinkable because it had been medical dogma for forty years or more that there was no ‘inside,’ no inner life, in the autistic, or that if there was it would be forever denied access or expression” (129). As Wolfe sees it, that dogma is founded in no small part on the too-rapid assimilation of the questions of subjectivity, consciousness, and cognition to the question of language ability—a dogma that is perhaps …

Little Red Herrings-Freedom, Freedom, Freeee-Dom, Mark Y. Herring

Against the Grain

No abstract provided.