Digital Commons Network^™

Silent Dissent: The Effect Of Structural Secrecy On Professional Communication At Nasa, Charlotte N. Hyde

Open Access Dissertations

This dissertation examines the creation and legitimization of knowledge through an examination of Dr. Warner von Braun’s weekly communications with his department heads during the Apollo project. My researched is focused on an archive of memos from the Marshall Space Flight Center during the 60’s. The memos were referred to as either Monday Notes or Weekly notes. I use the terms interchangeably, but some scholars differentiate between the two and refer to the Monday Notes as the communication system that worked during the Apollo project and the weekly notes as the communication system that broke after the Apollo project. In …

Biochemical Changes In Animal Models Of Fetal Alcohol Spectrum Disorder, Christine E. M. Keller

Open Access Dissertations

Fetal alcohol spectrum disorder (FASD) is a completely preventable disease, that has profound effects on life-long health and function of the affected individual. Prevalence estimates of FASD in the United States indicate 33.5 per 1,000 live births are affected with this disorder (Roozen, 2016). FASD is caused by maternal ethanol intake during pregnancy. However, recommendations of the amounts of alcohol safe to drink during pregnancy are not established. Further, we lack a comprehensive understanding of the biochemical pathways modified in prenatal ethanol exposure. Biomarkers are also lacking. Our results demonstrate the vast array of biochemical pathways modified in the chronic …

Synthetic Studies Of Heparan Derivatives: Glycosyl Couplings And Post-Glycosylative Modifications, Hari Raj Khatri

Open Access Dissertations

Heparan sulfate (HS) and closely related heparin are comprised of alternating units of D-glucosamine and either D-glucuronic acid (D-GluA) or L-iduronic acid (L-IdoA), and support variable degrees of sulfation which can interact with a large number of proteins with diverse biological functions. HS oligosaccharides can be constructed from readily accessible D-GlcN and D-GlcA derivatives, but the inclusion of L-IdoA is less straightforward. To address this, our laboratory has developed alternative synthetic strategies for HS-like oligosaccharides to incorporate either D-GlcA or L-IdoA in a synthetically efficient manner by nucleophilic ring opening of 4-epoxypyranosides, which can be made from readily available D-hexoses …

An Examination Of Indiana Early College High School Students Who Attended Purdue University Between 2006 And 2015, Lisa P. Kirkham

Open Access Dissertations

Early College High Schools (ECHS) are an educational intervention designed to promote rigor in high school education along with increased post-secondary access and success for disadvantaged students. Based on evidence, the Early College High School program is effective at helping students who traditionally are not in college-bound tracks find their way into that path. ECHSs provide a comprehensive, rigorous high school experience allowing students to earn an associate’s degree along with the high school diploma. Regarding structure, the ECHS is an entire high school, with all students earning college credits. Examining post-secondary experiences of students participating in Early College High …

Nanophotonics For Dark Materials, Filters, And Optical Magnetism, Mengren Man

Open Access Dissertations

Research on nanophotonic structures for three application areas is described, a near perfect optical absorber based on a graphene/dielectric stack, an ultraviolet bandpass filter formed with an aluminum/dielectric stack, and structures exhibiting homogenizable magnetic properties at infrared frequencies. The graphene stack can be treated as a effective, homogenized medium that can be designed to reflect little light and absorb an astoundingly high amount per unit thickness, making it an ideal dark material and providing a new avenue for photonic devices based on two-dimensional materials. Another material stack arrangement with thin layers of metal and insulator forms a multi-cavity filter that …

Disentangling Universal And Cultural-Specific Risks To Mental Health Among Asian Americans: A Multi-Site Longitudinal Investigation, Pan Priscilla Lui

Open Access Dissertations

Objective: Development-based intergenerational conflict related to separation-individuation is normative and similar across ethnocultural groups. Intergenerational cultural conflict related to acculturation mismatch—where intercultural contact leads parents and offspring to diverge in heritage and mainstream American values and behaviors—is specific to immigrant families. Although development-based conflict does not result in serious psychological distress or behavioral problems among healthy adolescents and emerging adults, acculturation-based conflict has been linked to maladjustment among offspring with immigrant parents in cross-sectional studies. The distinct and potentially mutually influential contributions of these types of conflict have not been evaluated as simultaneous processes unfolding during the developmentally significant transition …

Knitting Rebellion: Elizabeth Zimmermann, Identity, And Craftsmanship In Post War America, Maureen Lilly Marsh

Open Access Dissertations

At mid 20th century, hand knitting in the United States was practiced as a minor and fading chore of the domestic economy, with decreasing pattern publications in national women’s magazines, and the demise of Vogue Knitting Book by the late nineteen-sixties. By 1990, it had rebounded into major new publications in periodicals and books, new and revived artisanship practices, gallery exhibitions and major international conferences and gatherings. A driving figure in this resurgence was the knitter, writer, teacher, designer, and publisher Elizabeth Zimmermann. With her initial publication in 1955 up to her retirement in 1989, Elizabeth’s philosophy of knitting stressed …

Improving Online Food Safety Communication: The Role Of Media, Jing Ma

Open Access Dissertations

Food safety is important as foodborne illness outbreaks cause great economic and societal losses. Efforts to protect public health and reduce foodborne illness outbreaks will not be fully effective unless the resulting information is communicated to consumers.

However, food safety communications have not been particularly satisfactory (Worsfold, 2006). If food safety information were more accessible, consumers would be more likely to use it (Worsfold, 2006). In this regard, the Internet presents great possibilities for communicating food safety information to the public. But media’s role has been largely overlooked in existing literature. When the lack of research is combined with consumers’ …

Encounters Beyond The Interface: Data Structures, Material Feminisms, And Composition, Christine L. Masters

Open Access Dissertations

This dissertation argues that data literacy should be taught in college writing classes along with other new media literacies. Drawing from several areas of study, this dissertation establishes a definition of data literacy, introduces a feminist methodological approach to Big Data and data studies, and makes a case for teaching data literacy in first year composition and professional writing courses as a foundational writing-related literacy. Information written into and read from databases supports research activities in any number of fields from STEM to the humanities; while different disciplines approach databases and data structures from diverse perspectives, all students need foundational …

Investigation Of Cellular Microenvironments And Heterogeneity With Biodynamic Imaging, Daniel Alexander Merrill

Open Access Dissertations

Imaging of biological tissue in a relevant environment is critical to accurately assessing the effectiveness of chemotherapeutic agents in combatting cancer. Though many three-dimensional (3D) culture models exist, conventional in vitro assays continue to use two-dimensional (2D) cultures because of the difficulty in imaging through deep tissue. 3D tomographic imaging techniques exist and are being used in the development of 3D efficacy assays. However, most of these assays look at therapy endpoint (dead or living cancer cell count) and do not capture the dynamics of tissue response.

Biodynamic imaging (BDI) is a 3D tomographic imaging and assay technique that uses …

Decentering The Writing Program Archive: How Composition Instructors Save And Share Their Teaching Materials, Stacy Olivia Nall

Open Access Dissertations

This dissertation decenters the writing program archive through research on instructors’ digital archives. Artifacts of composition instruction are no longer saved to print archives alone; rather, digital technologies expand the locations where artifacts of writing pedagogy can be archived and accessed. The following archival ethnography, focused on a community engagement writing course in the Introductory Composition at Purdue (ICaP) program, finds that many digital archives of composition are hidden to outside researchers or not sustained (which are theorized as either “abandoned” or “pop-up” archives). At the same time, some pedagogical materials are publicly visible by virtue of personal web spaces …

Gap Analysis Identifying The Current State Of Information Security Within Organizations Working With Victims Of Violence, Kelley K. Misata

Open Access Dissertations

Around the world, domestic violence, human trafficking, and stalking affect millions of lives every day. According to a report published by the Center for Disease Control and Prevention in January 2015, every minute 20 people fall victim to physical violence perpetrated by an intimate partner in the United States (US). As offenders use advancements in technology to perpetuate abuse and isolate victims, the scale of services provided by crisis organizations must rise to meet the demand while keeping a close eye on potential digital security vulnerabilities. It has been reported in general media and research that phishing emails, social engineering …

Influence Of Dietary Polyphenols On Carbohydrate Intestinal Digestion And Absorption, Sydney E. Moser

Open Access Dissertations

Both epidemiological and clinical evidence support the notion that polyphenol rich foods and beverages may modify glycemic response, glucose homeostasis and subsequent risk of Type-2 diabetes. In vitro evidence typically derived from experiments with pure phenolics and phenolic rich extracts have pointed to this benefit being associated with two potential mechanisms: (1) the ability of specific polyphenolics to inhibit carbohydrate digestion (amylase and glucosidase) and (2) polyphenolic inhibition of intestinal glucose transport. While the high potential of these activities is evident, little is actually known regarding the extent to which these benefits are extendable to the actual food matrix these …

Fabrication And Characterization Of Cellulose Nanocrystal Enhanced Sustainable Polymer Nanocomposites Through Surface Chemistry And Processing, Shane X. Peng

Open Access Dissertations

Cellulose nanocrystals (CNCs) belong to a class of cellulose based nanomaterials that are extracted from renewable and sustainable sources and have excellent mechanical and thermal properties. While applications for CNCs have been expanding, one of the challenges of utilizing CNCs is to overcome their low dispersibility in hydrophobic polymers. In the present work, several approaches are utilized to improve the interfacial compatibility and overall performance of CNC/epoxy and CNC/polyamide nanocomposite.

For a two-part epoxy system, a novel approach was taken to disperse CNC in epoxy matrix by pre-formulating CNC into the hardeners. Three types of hardeners were evaluated for their …

From Mechanic To Designer: Evolving Perceptions Of Elementary Students Over Three Years Of Engineering Instruction, Anastasia M. Rynearson

Open Access Dissertations

Due in part to increasing state standards that require engineering in K-12 curricula and the Next Generation Science Standards’ incorporation of engineering outcomes, inclusion of engineering into elementary classrooms is on the rise. Teacher development and experiences in learning about and implementing engineering have been studied, but elementary students’ experiences when learning about engineering have not been explored.

The purpose of this study is to address the question: How do elementary students’ knowledge of, attitudes toward, and overall conceptions of engineering evolve over three years of engineering instruction?

This study follows seven elementary school students through three years of engineering …

South Asian Women's Sexual Relationship Power: Examining The Role Of Sexism, Cultural Values Conflict, Discrimination, And Social Support, Chandni D. Shah

Open Access Dissertations

The lack of literature examining sexual experiences of South Asian women in dating relationships has important implications for the healthy development of long lasting romantic relationships. It is important to understand South Asian women’s relationship experiences in the context of power and sexism (interpersonal power framework; Pulerwitz, Gortmaker, & DeJong, 2000) and the role of specific sociopolitical factors (e.g., discrimination). Understanding South Asian women’s experiences of power in a sociopolitical context will help professionals when working with them to develop healthier sexual relationships through therapy outreach, and community programming. I used a correlational, quantitative study to examine the associations between …

Emerging Genres, Dangerous Classifications: The Kairos Of Digital Composing Policy, Ellery Sills

Open Access Dissertations

Emerging Genres, Dangerous Classifications: The Kairos of Digital Composing Policy argues that writing policy infrastructure plays a significant (if often invisible) role in affording emerging digital genres in rhetoric and composition. Within the last few decades, the accelerating transformations and instabilities of emerging genres have posed a challenge for contemporary writing programs, which demonstrate a persistent wariness over incorporating digital composing into their mission. In response to this challenge, national educational associations have issued a growing number of policy statements meant to encourage a broader understanding of composing in the classroom. Curiously, relatively little scholarly attention has been paid to …

Psychosocial Factors And Mental Health Of Muslims Living In The United States, Lamise N. Shawahin

Open Access Dissertations

Muslim Americans are at risk for experiencing systematic and interpersonal acts of discrimination (Rippy & Newman, 2006). Such experiences of discrimination can lead to the development of depressive symptoms. Thus, it is critical to understand factors that may influence the relationship between experiencing discrimination and developing depressive symptoms. The purpose of the present study was to examine the relationship between psychosocial adversities (i.e., perceived discrimination), psychosocial resources (i.e., coping strategies, religious community support) and depressive symptoms. Hypotheses regarding both the relationships among the variables, as well as the mediating role psychosocial resources play in the relationship between perceived discrimination and …

Coupling Qualitative And Quantitative Analyses Of Pharmaceutical Materials Enabled By Second Harmonic Generation Microscopy, Paul D. Schmitt

Open Access Dissertations

The detection and characterization of crystallinity is critical throughout the drug development process. From the initial establishment of an active pharmaceutical ingredient’s (API) crystal structure to stability testing and quality control, the phase of an API affects the solubility, bioavailability, stability, and efficacy of a drug product. Second harmonic generation (SHG) microscopy has recently been developed as a selective and rapid method for imaging crystallinity in drug formulations. While SHG microscopy can enable the high signal-to-noise (SNR) detection of crystallinity, the intrinsic chemical information content within SHG images is relatively low. In cases of trace crystallinity and/ or small crystal …

An Analysis Of The Current Strength Of The Academic Relationship With The Aerospace Industry, James A. Stratton

Open Access Dissertations

The objective of this research was to discover which methods of technology transfer were most commonly accessed within the Indiana manufacturing sector in an effort to best serve companies in the Hoosier State. Previous work has explored the perceived importance of various academic sources, but there has not been an investigation to identify the specific preferences of industry professionals. If these preferences can be identified, university assistance programs and other academic engagement programs will be able to predict, and hopefully influence how to grow and develop the domestic manufacturing sector, ultimately strengthening the channels of knowledge transfer between academia and …

The Graphic Side Of Fear: The Effects Of Anti-Tobacco Graphic Threat Appeals, Latasha R. Swanson

Open Access Dissertations

Many public health organizations have proposed and implemented campaigns and policies involving graphic ads or warnings to deter individuals from smoking. The current study evaluated how high-cigarette dependent smokers evaluate these messages compared to low-cigarette dependent smokers using a mixed, 3 x 2 factorial design. A pilot study involving focus groups, interviews, and evaluation questionnaires (N=10) was conducted to classify graphic threat appeals and develop stimulus materials for the primary study. For the primary study, three graphic threat appeal conditions were evaluated by Amazon Mechanical Turk (MTurk) users (N=200). Findings suggested that the graphicness of the …

Ultrasound And Photoacoustic Methods For Anatomic And Functional Imaging In Image Guided Radiation Therapy, Justin T. Sick

Open Access Dissertations

(MATERIAL and METHODS) First, we define the physical principals and optimal protocols that provide contrast when imaging with US and the transducer properties contributing to resolution limits. The US field of view (FOV) was characterized to determine the optimal settings with regard to imaging depth, focal region, with and without harmonic imaging, and artifact identification. This will allow us to determine the minimum errors expected when registering multimodal volumes (CT, US, CBCT).

Next, we designed an in-house integrated US manipulator and platform to relate CT, 3D-US and linear accelerator coordinate systems. To validate our platform, an agar-based phantom with measured …

Physical Properties, Evaporation And Combustion Characteristics Of Nanofluid-Type Fuels, Saad Tanvir

Open Access Dissertations

Nanofluids are liquids with stable suspension of nanoparticles. Limited studies in the past have shown that both energetic and catalytic nanoparticles once mixed with traditional liquid fuels can be advantageous in combustion applications, e.g., increased energy density and shortened ignition delay. Contradictions in existing literature, scarcity of experimental data and lack of understanding on how the added nanoparticles affect the physical properties as well as combustion characteristics of the resulting fuel motivated us to launch a detailed experimental and theoretical investigation.

The surface tension of ethanol and n-decane based nanofluid fuels containing suspended nanoparticles were measured using the pendant drop …

Essays In Labor Economics And Panel Data Analysis, Evan S. Totty

Open Access Dissertations

This dissertation is composed of three independent chapters. The first chapter studies the impact of minimum wage hikes on employment of low-skill workers in the United States. The second chapter studies the lasting impact of attending a higher value-added high school on college performance. The third chapter studies the impact of stuttering on labor market outcomes.

The first chapter resolves issues in the minimum wage-employment debate by using factor model econometric methods to address concerns related to unobserved heterogeneity. Recent work has shown that the negative effects of minimum wages on employment found using traditional methods are sensitive to the …

Evaluating The Prevalence And Effectiveness Of Breed-Specific Legislation, Felicia E. Trembath

Open Access Dissertations

Dog bites pose a persistent public health problem, which some jurisdictions pass breed-specific legislation (BSL) to address. However, very little non-anecdotal evidence regarding the efficacy of BSL has been presented. Currently, BSL research is hampered by the absence of standard terminology, an established prevalence, or a scientific consensus on its effectiveness. The purpose of this study is to propose standardized terminology for BSL, establish the prevalence of each type of BSL in the USA, and conduct a systematic review of the effectiveness of BSL.

After review of terminology currently in use, as well as review of the regulatory actions of …

After The Honeymoon: The Obama Effect On Political Attitudes And Participation, Laurent W. Vesely

Open Access Dissertations

My dissertation takes a mixed-methods approach to investigating the possibility of a lasting Obama Effect on the political attitudes and behaviors of Obama supporters from 2008. Defining the Obama Effect as the extraordinary enthusiasm surrounding Barack Obama’s 2008 campaign, I argue that a short term Obama Effect was clearly present in 2008 based on Obama’s electoral success, fundraising prowess, and ability to inspire volunteerism, as well as on the historic nature of his candidacy. But I ask, was it a lasting effect? My quantitative analyses—built upon panel survey data from the American National Election Studies—suggest little evidence of a lasting …

China Twenty Years After: Substance Use Under Rapid Social Changes, Xiaozhao Y. Yang

Open Access Dissertations

This dissertation discusses how China’s rapid modernization and social transformation over the last twenty years since a series of reforms at the end of 1980s contribute to the changes in substance use behaviors. Specifically, there are three individual empirical chapters in this dissertation, each exploring one dimension of social change and its association with substance use. First, I have demonstrated how substance use can be a protective factor against unemployment over the long term, especially against the background of massive layoffs among former socialist industrial workers and landless peasants during this period. Second, another chapter examines how social mobility (i.e. …

Physiological Bases And A Novel Genetic Determinant Of Water-Use Efficiency (Wue), Jie Yin

Open Access Dissertations

Water-use efficiency (WUE), the ratio of biomass to water loss, is a heritable but complex trait, the genetic basis of which is largely unknown. We utilized diverse accessions of the halophyte Eutrema salsugineum to ultimately identify a novel genetic determinant of WUE. E. salsugineum accessions from locations with low water availability, temperature, and radiation have lower transpirational water loss and greater biomass, resulting in higher WUE. High-WUE accessions also have lower stomatal density and index and larger thinner leaves than low-WUE accessions. We identified 14,808 single nucleotide polymorphisms (SNPs) between two accessions of E. salsugineum,Shandong (SH) and Yukon (YK), …

Seismic Body-Wave Interferometry Using Noise Autocorrelations For Crustal Structure And A Tutorial On 3d Seismic Processing And Imaging Using Madagascar, Can Oren

Open Access Theses

Seismic body-wave interferometry is applied to selected seismic stations from the USArray Earthscope Transportable Array (TA) by autocorrelating ambient seismic noise recordings to construct effective zero-offset reflection seismograms. The robustness of the auto-correlations of noise traces is first tested on a TA station in Nevada where body-wave reflections similar to those found in an earlier study are identified. This approach is then applied to several TA stations in the central U.S., and the results are compared with synthetic data. Different stacking time periods are then examined to find the shortest time intervals that provide stable correlation stacks.

A tutorial on …

Fructose 1,6-Bisphosphate Aldolase, A Novel Immunogenic Surface Protein On Listeria Species, Mercelo L. Mendonça, Gustavo Marçal Schmidt Garcia Moreira, Fabrício Fabrício Conceição, Michael Hust, Karla Sequeira Mendonça, Ângela Nunes Moreira, Rodrigo Correa Orrea França, Wladimir Padilha Da Silva, Arun K. Bhunia, José Antônio Guimarães Uimarães Aleixo

Department of Food Science Faculty Publications

Listeria monocytogenes is a ubiquitous food-borne pathogen, and its presence in food or production facilities highlights the importance of surveillance. Increased understanding of the surface exposed antigens on Listeria would provide potential diagnostic and therapeutic targets. In the present work, using mass spectrometry and genetic cloning, we show that fructose-1,6-bisphosphate aldolase (FBA) class II in Listeria species is the antigen target of the previously described mAb-3F8. Western and dot blot assays confirmed that the mAb-3F8 could distinguish all tested Listeria species from close-related bacteria. Localization studies indicated that FBA is present in every fraction of Listeria cells, including supernatant and …