Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

Old Dominion University

Discipline
Keyword
Publication Year
Publication
Publication Type
File Type

Articles 3841 - 3870 of 6160

Full-Text Articles in Entire DC Network

Hierarchical Linear Modeling Of Drinking To Cope With Anxiety Among College Students, Bradley Wetzell, Matthew R. Pearson, James Henson Jan 2010

Hierarchical Linear Modeling Of Drinking To Cope With Anxiety Among College Students, Bradley Wetzell, Matthew R. Pearson, James Henson

OUR Journal: ODU Undergraduate Research Journal

Previous research has assumed that drinking motives (reasons for drinking) remain fairly stable over time (traits). The current study examines how drinking motives of college students may vary over time (states). Weekly measures were completed by 125 undergraduates at Old Dominion University, which examined how average levels of anxiety interacted with anxiety coping motives to influence drinking. Using Hierarchical Linear Modeling, it was found that anxiety coping motives were less predictive for participants with elevated average anxiety levels, as opposed to participants with normal to low anxiety levels. Implications and possible explanations are discussed.

Research Mentor: Dr. James Henson, Department …


Credits Jan 2010

Credits

OUR Journal: ODU Undergraduate Research Journal

No abstract provided.


Mesoscopic Methods In Engineering And Science, Alfons Hoekstra, Li-Shi Luo, Manfred Krafczyk Jan 2010

Mesoscopic Methods In Engineering And Science, Alfons Hoekstra, Li-Shi Luo, Manfred Krafczyk

Mathematics & Statistics Faculty Publications

(First paragraph) Matter, conceptually classified into fluids and solids, can be completely described by the microscopic physics of its constituent atoms or molecules. However, for most engineering applications a macroscopic or continuum description has usually been sufficient, because of the large disparity between the spatial and temporal scales relevant to these applications and the scales of the underlying molecular dynamics. In this case, the microscopic physics merely determines material properties such as the viscosity of a fluid or the elastic constants of a solid. These material properties cannot be derived within the macroscopic framework, but the qualitative nature of the …


Making Parents: Conventions, Intentions, And Biological Connections, Yvette Pearson, Stephen Scales (Ed.), Linda Oravecz (Ed.), Adam Potthast (Ed.) Jan 2010

Making Parents: Conventions, Intentions, And Biological Connections, Yvette Pearson, Stephen Scales (Ed.), Linda Oravecz (Ed.), Adam Potthast (Ed.)

Philosophy Faculty Publications

No abstract provided.


Experiencing Emotional Abuse During Childhood And Witnessing Interparental Verbal Aggression As Related To Emotional Aggression In Undergraduate Dating Relationships, Robert J. Milletich, Michelle Kelley Jan 2010

Experiencing Emotional Abuse During Childhood And Witnessing Interparental Verbal Aggression As Related To Emotional Aggression In Undergraduate Dating Relationships, Robert J. Milletich, Michelle Kelley

OUR Journal: ODU Undergraduate Research Journal

The present study examined whether witnessing interparental verbal aggression and/or experiencing emotional abuse during childhood were associated with emotional abuse in current or recent dating relationships in college students (M = 19.51 years; SD = 2.02). Participants (N = 715) completed the Conflicts Tactics 2-CA Scale (Straus & Donnelly, 2001), the Exposure to Abusive and Supportive Environments Parenting Inventory (Nicholas & Bieber, 1997), and the Emotional Abuse Scale (Murphy & Hoover, 1999). Results showed that witnessing interparental verbal aggression predicted males‟ self-use of Restrictive Engulfment and their partners‟ use of Restrictive Engulfment. For females, witnessing interparental verbal aggression predicted self-use …


Towards A Center For Modeling And Simulation: The Case For Jordan, Ghaith Rabadi, Hazem Kaylani, Joseph Barjis (Ed.), Murali Mohan Narasipuram (Ed.), Ghaith Rabadi (Ed.), Jolita Ralyt (Ed.), Pierluigi Plebani (Ed.) Jan 2010

Towards A Center For Modeling And Simulation: The Case For Jordan, Ghaith Rabadi, Hazem Kaylani, Joseph Barjis (Ed.), Murali Mohan Narasipuram (Ed.), Ghaith Rabadi (Ed.), Jolita Ralyt (Ed.), Pierluigi Plebani (Ed.)

Engineering Management & Systems Engineering Faculty Publications

Modeling and Simulation (M&S) has recently become an important area that is pursued by many researchers and practitioners due to the role it plays in understanding complex systems and problems. We have therefore witnessed the establishment of many M&S organizations in the last two decades especially in the more developed world. Less developed countries are starting to recognize the need for such capability especially that the problems they face are not less complex. In this paper, we present a preliminary study towards a business plan for establishing a scientific center for Modeling, Analysis, Simulation and Animation in Jordan (JoSAMA) and …


Frustrated Drift Of An Anchored Scroll-Wave Filament And The Geodesic Principle, Marcel Wellner, Christian W. Zemlin, Arkady M. Pertsov Jan 2010

Frustrated Drift Of An Anchored Scroll-Wave Filament And The Geodesic Principle, Marcel Wellner, Christian W. Zemlin, Arkady M. Pertsov

Bioelectrics Publications

We investigate anchored scroll-wave filaments in an excitable medium whose diffusivity matrix, including its determinant, is spatially nonuniform. The study is motivated by cardiological applications where scroll-wave behavior in the presence of diffusivity gradients is believed to play an important role in the development of severe arrhythmias. A diffusivity gradient is expected to make the filament drift, unless drift is prevented ("frustrated") by anchoring to localized defects in the propagation medium. The resulting stationary filament is a geodesic curve, as demonstrated here in the case of a nonzero but constant gradient. That is, the diffusivity matrix has a determinant that …


Variable Number Of Tandem Repeat Polymorphisms (Vntrs) In The Acan Gene Associated With Pectus Excavatum, Michael W. Stacey, Serina Neumann, Ashley Dooley, Kara Segna, Robert Kelly, Donald Nuss, Anne Kuhn, Michael Goretsky, Annie Fecteau, Aimee Pastor, Virginia Proud Jan 2010

Variable Number Of Tandem Repeat Polymorphisms (Vntrs) In The Acan Gene Associated With Pectus Excavatum, Michael W. Stacey, Serina Neumann, Ashley Dooley, Kara Segna, Robert Kelly, Donald Nuss, Anne Kuhn, Michael Goretsky, Annie Fecteau, Aimee Pastor, Virginia Proud

Bioelectrics Publications

No abstract provided.


Electroporation-Mediated Delivery Of A Naked Dna Plasmid Expressing Vegf To The Porcine Heart Enhances Protein Expression, W. G. Marshall Jr., B. A. Boone, J. D. Burgos, S. I. Gografe, M. K. Baldwin, M. L. Danielson, M. J. Larson, D. R. Caretto, Y. Cruz, B. Ferraro, L. C. Heller, K. E. Ugen, M. J. Jaroszeski, R. Heller Jan 2010

Electroporation-Mediated Delivery Of A Naked Dna Plasmid Expressing Vegf To The Porcine Heart Enhances Protein Expression, W. G. Marshall Jr., B. A. Boone, J. D. Burgos, S. I. Gografe, M. K. Baldwin, M. L. Danielson, M. J. Larson, D. R. Caretto, Y. Cruz, B. Ferraro, L. C. Heller, K. E. Ugen, M. J. Jaroszeski, R. Heller

Bioelectrics Publications

Gene therapy is an attractive method for the treatment of cardiovascular disease. However, using current strategies, induction of gene expression at therapeutic levels is often inefficient. In this study, we show a novel electroporation (EP) method to enhance the delivery of a plasmid expressing an angiogenic growth factor (vascular endothelial growth factor, VEGF), which is a molecule previously documented to stimulate revascularization in coronary artery disease. DNA expression plasmids were delivered in vivo to the porcine heart with or without coadministered EP to determine the potential effect of electrically mediated delivery. The results showed that plasmid delivery through EP significantly …


Benthic Ecology From Space: Optics And Net Primary Production In Seagrass And Benthic Algae Across The Great Bahama Bank, Heidi M. Dierssen, Richard C. Zimmerman, Lisa A. Drake, David J. Burdige Jan 2010

Benthic Ecology From Space: Optics And Net Primary Production In Seagrass And Benthic Algae Across The Great Bahama Bank, Heidi M. Dierssen, Richard C. Zimmerman, Lisa A. Drake, David J. Burdige

OES Faculty Publications

Development of repeatable and quantitative tools are necessary for determining the abundance and distribution of different types of benthic habitats, detecting changes to these ecosystems, and determining their role in the global carbon cycle. Here we used ocean color remote sensing techniques to map different major groups of primary producers and estimate net primary productivity (NPP) across Great Bahama Bank (GBB). Field investigations on the northern portion of the GBB in 2004 revealed 3 dominant types of benthic primary producers: seagrass, benthic macroalgae, and microalgae attached to sediment. Laboratory measurements of NPP ranged from barely net autotrophic for grapestone sediment …


On The Fractional Solubillity Of Copper In Marine Aerosols: Toxicity Of Aeolian Copper Revisited, Edward R. Sholkovitz, Peter N. Sedwick, Thomas M. Church Jan 2010

On The Fractional Solubillity Of Copper In Marine Aerosols: Toxicity Of Aeolian Copper Revisited, Edward R. Sholkovitz, Peter N. Sedwick, Thomas M. Church

OES Faculty Publications

Paytan et al. (2009) argue that the atmospheric deposition of aerosols lead to copper concentrations that are potentially toxic to marine phytoplankton in a large area of tropical and subtropical North Atlantic Ocean. A key assumption in their model is that all marine aerosols (mineral dust and anthropogenic particles) have a high (40%) fractional solubility of copper. Our data show that the fractional solubility of copper for Saharan dust over the Sargasso Sea and Bermuda is significantly lower (1-7%). In contrast, anthropogenic aerosols with non-Saharan sources have significantly higher values (10-100%). Hence, the potential Cu toxicity in the tropical and …


Modeling The Vertical Distributions Of Downwelling Plane Irradiance And Diffuse Attenuation Coefficient In Optically Deep Waters, X. J. Pan, Richard C. Zimmerman Jan 2010

Modeling The Vertical Distributions Of Downwelling Plane Irradiance And Diffuse Attenuation Coefficient In Optically Deep Waters, X. J. Pan, Richard C. Zimmerman

OES Faculty Publications

The diffuse attenuation coefficient Kᵈ is critical to understand the vertical distribution of underwater downwelling irradiance (Eᵈ). Theoretically Eᵈ is composed of the direct solar beam and the diffuse sky irradiance. Applying the statistical results from Hydrolight radiative transfer simulations, Kᵈ is expressed into a mathematical equation (named as PZ06) integrated from the contribution of direct solar beam and diffuse sky irradiance with the knowledge of sky and water conditions. The percent root mean square errors (RMSE) for the vertical distribution of Eᵈ(z) under various sky and water conditions between PZ06 and Hydrolight results are typically less than 4%. Field …


The Path To Preservation: Using Proteomics To Decipher The Fate Of Diatom Proteins During Microbial Degradation, Brook L. Nunn, Ying S. Ting, Lars Malmström, Yihsuan S. Tsai, Angela Aquier, David R. Goodlett, H. Rodger Harvey Jan 2010

The Path To Preservation: Using Proteomics To Decipher The Fate Of Diatom Proteins During Microbial Degradation, Brook L. Nunn, Ying S. Ting, Lars Malmström, Yihsuan S. Tsai, Angela Aquier, David R. Goodlett, H. Rodger Harvey

OES Faculty Publications

We drew upon recent advances in tandem mass spectrometry-based proteomic analyses in order to examine the proteins that remain after a diatom bloom enters the stationary phase, precipitates out of the photic zone, and is subjected to microbial degradation over a 23-d period within a controlled laboratory environment. Proteins were identified from tandem mass spectra searched against three different protein databases in order to track proteins from Thalassiosira pseudonana and any potential bacterial contributions. A rapid loss of diatom protein was observed over the incubation period; 75% of the proteins initially identified were not detected after 72 h of exposure …


Turbulent Mixing In A Strongly Forced Salt Wedge Estuary, David K. Ralston, W. Rockwell Geyer, James A. Lerczak, Malcolm Scully Jan 2010

Turbulent Mixing In A Strongly Forced Salt Wedge Estuary, David K. Ralston, W. Rockwell Geyer, James A. Lerczak, Malcolm Scully

OES Faculty Publications

Turbulent mixing of salt is examined in a shallow salt wedge estuary with strong fluvial and tidal forcing. A numerical model of the Merrimack River estuary is used to quantify turbulent stress, shear production, and buoyancy flux. Little mixing occurs during flood tides despite strong velocities because bottom boundary layer turbulence is dislocated from stratification elevated in the water column. During ebbs, bottom salinity fronts form at a series of bathymetric transitions. At the fronts, near-bottom velocity and shear stress are low, but shear, stress, and buoyancy flux are elevated at the pycnocline. Internal shear layers provide the dominant source …


Effect Of The Heterotrophic Dinoflagellate Oxyrrhis Marina And The Copepod Acartia Tonsa On Vertical Carbon Flux In And Around Thin Layers Of The Phytoflagellate Isochrysis Galbana, A. B. Bochdansky, S. M. Bollens, G. C. Rollwagen-Bollens, A. H. Gibson Jan 2010

Effect Of The Heterotrophic Dinoflagellate Oxyrrhis Marina And The Copepod Acartia Tonsa On Vertical Carbon Flux In And Around Thin Layers Of The Phytoflagellate Isochrysis Galbana, A. B. Bochdansky, S. M. Bollens, G. C. Rollwagen-Bollens, A. H. Gibson

OES Faculty Publications

Dynamics of material and energy flow through food webs differ when resources are allocated in patches in comparison to situations in which the same resources are distributed evenly throughout the water column. Thin layers of plankton are special cases of such resource patches. While previous studies have predominantly focused on the response of organisms to these layers, we investigated how 2 types of grazers in turn affect thin layers. In an experimental study with tightly controlled environmental conditions, we monitored the redistribution of particulate organic (POC), dissolved organic (DOC) and inorganic (DIC) carbon from thin layers of Isochrysis galbana. …


Role Of Macroscopic Particles In Deep-Sea Oxygen Consumption, Alexander B. Bochdansky, Hendrik M. Van Aken, Gerhard J. Herndl Jan 2010

Role Of Macroscopic Particles In Deep-Sea Oxygen Consumption, Alexander B. Bochdansky, Hendrik M. Van Aken, Gerhard J. Herndl

OES Faculty Publications

Macroscopic particles (> 500 µg), including marine snow, large migrating zooplankton, and their fast-sinking fecal pellets, represent primary vehicles of organic carbon flux from the surface to the deep sea. In contrast, freely suspended microscopic particles such as bacteria and protists do not sink, and they contribute the largest portion of metabolism in the upper ocean. In bathy- and abyssopelagic layers of the ocean (2,000-6,000 m), however, microscopic particles may not dominate oxygen consumption. In a section across the tropical Atlantic, we show that macroscopic particle peaks occurred frequently in the deep sea, whereas microscopic particles were barely detectable. In …


Determination Of Total Dissolved Cobalt In Uv-Irradiated Seawater Using Flow Injection With Chemiluminescence Detection, Rachel U. Shelley, Bernhard Zachhuber, Peter N. Sedwick, Paul J. Worsfold, Maeve C. Lohan Jan 2010

Determination Of Total Dissolved Cobalt In Uv-Irradiated Seawater Using Flow Injection With Chemiluminescence Detection, Rachel U. Shelley, Bernhard Zachhuber, Peter N. Sedwick, Paul J. Worsfold, Maeve C. Lohan

OES Faculty Publications

A sensitive flow-injection method with chemiluminescence detection (FI-CL) for the determination of dissolved cobalt in open ocean samples, suitable for shipboard use has been developed. To date, FI methods for dissolved cobalt have been used only in coastal and estuarine waters. Therefore, significant modifications to existing methods were required, including (1) the use of a commercially available iminodiacetate (IDA) resin (Toyopearl AF-chelate 650M) in place of resin immobilized 8-hydroxyquinoline for online preconcentration and matrix removal, (2) the introduction of acidified ammonium acetate (pH 4) as a column-conditioning step before sample loading and rinse steps, and most importantly, (3) UV irradiation …


Theory Of Island Biogeography On A Microscopic Scale: Organic Aggregates As Islands For Aquatic Pathogens, M. M. Lyons, J. E. Ward, Holly Gaff, R. E. Hicks, J. M. Drake, Fred C. Dobbs Jan 2010

Theory Of Island Biogeography On A Microscopic Scale: Organic Aggregates As Islands For Aquatic Pathogens, M. M. Lyons, J. E. Ward, Holly Gaff, R. E. Hicks, J. M. Drake, Fred C. Dobbs

OES Faculty Publications

Four predictions of the MacArthur-Wilson theory of island biogeography were evaluated to assess the degree to which detrital-based organic aggregates (e.g. marine snow, organic detritus, and bioflocs) may provide a favorable microhabitat (i.e. an 'island') for bacteria in general, and specifically aquatic pathogens. We demonstrate the theory's relevance for microbial communities in aquatic environments by describing the community metabolic response and functional diversity of individual organic aggregates while documenting the persistence of potential pathogens and fecal indicator bacteria. Our results support the 4 predictions, including a significant species-area relationship, consistency of species richness at equilibrium, non-zero level of species turnover …


A Seasonal Study Of Dissolved Cobalt In The Ross Sea, Antarctica: Micronutrient Behavior, Absence Of Scavenging, And Relationships With Zd, Cd, And P., M. A. Saito, T. J. Goepfert, A. E. Noble, E. M. Bertrand, Peter N. Sedwick, Giacomo R. Ditullio Jan 2010

A Seasonal Study Of Dissolved Cobalt In The Ross Sea, Antarctica: Micronutrient Behavior, Absence Of Scavenging, And Relationships With Zd, Cd, And P., M. A. Saito, T. J. Goepfert, A. E. Noble, E. M. Bertrand, Peter N. Sedwick, Giacomo R. Ditullio

OES Faculty Publications

We report the distribution of cobalt (Co) in the Ross Sea polynya during austral summer 2005-2006 and the following austral spring 2006. The vertical distribution of total dissolved Co (dCo) was similar to soluble reactive phosphate (PO(4)(3-)), with dCo and PO(4)(3-) showing a significant correlation throughout the water column (r(2) = 0.87, 164 samples). A strong seasonal signal for dCo was observed, with most spring samples having concentrations ranging from similar to ~ 45-85 pM, whereas summer dCo values were depleted below these levels by biological activity. Surface transect data from the summer cruise revealed concentrations at the low range …


Variations In Synechococcus Cell Quotas Of Phosphorus, Sulfur, Manganese, Iron, Nickel, And Zinc Within Mesoscale Eddies In The Sargasso Sea, Benjamin S. Twining, Daliangelis Nunez-Milland, Stefan Vogt, Rodney S. Johnson, Peter N. Sedwick Jan 2010

Variations In Synechococcus Cell Quotas Of Phosphorus, Sulfur, Manganese, Iron, Nickel, And Zinc Within Mesoscale Eddies In The Sargasso Sea, Benjamin S. Twining, Daliangelis Nunez-Milland, Stefan Vogt, Rodney S. Johnson, Peter N. Sedwick

OES Faculty Publications

The quotas of P, S, Mn, Fe, Ni, and Zn in individual Synechococcus cells collected from the surface and deep chlorophyll maximum (DCM) layer of three mesoscale eddies in the Sargasso Sea were measured using synchrotron X-ray fluorescence microscopy. Cells in a mode-water eddy had significantly higher P (57 +/- 10 amol) and Mn (28 +/- 7 zmol) cell quotas than cells collected from a cyclone (22 +/- 2 amol and 10 +/- 1 zmol, respectively) or anticyclone (25 +/- 3 amol and 18 +/- 3 zmol, respectively). Conversely, Ni and Zn quotas were significantly higher in the cells from …


Exchange Across The Shelf Break At High Southern Latitudes, J. M. Klinck, M. S. Dinniman Jan 2010

Exchange Across The Shelf Break At High Southern Latitudes, J. M. Klinck, M. S. Dinniman

CCPO Publications

Exchange of water across the Antarctic shelf break has considerable scientific and societal importance due to its effects on circulation and biology of the region, conversion of water masses as part of the global overturning circulation and basal melt of glacial ice and the consequent effect on sea level rise. The focus in this paper is the onshore transport of warm, oceanic Circumpolar Deep Water (CDW); export of dense water from these shelves is equally important, but has been the focus of other recent papers and will not be considered here. A variety of physical mechanisms are described which could …


Apoptosis Initiation And Angiogenesis Inhibition: Melanoma Targets For Nanosecond Pulsed Electric Fields, Xinhua Chen, Juergen F. Kolb, R. James Swanson, Karl H. Schoenbach, Stephen J. Beebe Jan 2010

Apoptosis Initiation And Angiogenesis Inhibition: Melanoma Targets For Nanosecond Pulsed Electric Fields, Xinhua Chen, Juergen F. Kolb, R. James Swanson, Karl H. Schoenbach, Stephen J. Beebe

Bioelectrics Publications

Many effective anti-cancer strategies target apoptosis and angiogenesis mechanisms. Applications of non-ionizing, nanosecond pulsed electric fields (nsPEFs) induce apoptosis in vitro and eliminate cancer in vivo; however in vivo mechanisms require closer analysis. These studies investigate nsPEF-induced apoptosis and anti-angiogenesis examined by fluorescent microscopy, immunoblots, and morphology. Six hours after treatment with one hundred 300 ns pulses at 40 kV/cm, cells transiently expressed active caspases indicating that caspase-mediated mechanisms. Three hours after treatment transient peaks in Histone 2AX phosphorylation coincided with terminal deoxynucleotidyl transferase dUTP nick end labeling positive cells and pyknotic nuclei, suggesting caspase-independent mechanisms on nuclei/DNA. Large …


Breathing Like A Fish, Petros J. Katsioloudis Jan 2010

Breathing Like A Fish, Petros J. Katsioloudis

STEMPS Faculty Publications

The article offers information on industrial oxygen rebreathers, an underwater breathing equipment used by divers. It states that rebreather is an electromechanical device that supply breathing gas through infusion of oxygen and reprocessing of carbon dioxide by using a chemical scrubber. It mentions that most rebreathers comprise of breathing loop, breathing lungs, and a canister where the scrubber is placed with the partial pressure (pO2) sensors and interface devices like heads-up display (HUD) to show pO2 levels. It also discusses types of rebreathers such as the oxygen rebreather, the oldest rebreather mainly used by navy diver, and …


Micro-Environment And Plant Assemblage Structure On Virginia's Barrier Island "Pimple" Dunes, Brett A. Mcmillan, Frank P. Day Jan 2010

Micro-Environment And Plant Assemblage Structure On Virginia's Barrier Island "Pimple" Dunes, Brett A. Mcmillan, Frank P. Day

Biological Sciences Faculty Publications

“Pimple” dunes are small, rounded coastal dunes that form along major dune ridges of the barrier islands along the Eastern Shore of Virginia. Although most pimple dunes are small structures ranging between 10 and 20 m in diameter, they have distinct plant assemblages that replicate the upland ecotones of their barrier islands. We examined the relationship between microenvironment, edaphic factors, and plant assemblage structure on pimple dunes. Water availability was an obvious major ecological driver, but we also tested other environmental factors that may correlate with plant assemblage structure. We found distinct assemblage types that segregated themselves by habitat type: …


Spawning-Related Movements Of Barred Sand Bass Paralabrax Nebulifer, In Southern California: Interpretations From Two Decades Of Historical Tag And Recapture Data, E. T. Jarvis, Christi Linardich, C. F. Valle Jan 2010

Spawning-Related Movements Of Barred Sand Bass Paralabrax Nebulifer, In Southern California: Interpretations From Two Decades Of Historical Tag And Recapture Data, E. T. Jarvis, Christi Linardich, C. F. Valle

Biological Sciences Faculty Publications

During the 1960s and 1990s, the California Department of Fish and Game tagged 8,634 barred sand bass in southern California, and 972 fish (11%) were recaptured. Tag returns suggest barred sand bass are transient aggregate spawners that form spawning aggregations consisting of both resident and migrant individuals. Spawning residency at a historic spawning location was estimated by the frequency of returns over time; most same-year returns (82%, n  =  141) were recaptured within a 7 to 35-day period. The maximum recapture distance was 92 km. The average (± SD) non-spawning season recapture distance from peak spawning season tagging locations was …


Prospective Associations Of Insomnia Markers And Symptoms With Depression, Mariana Szklo-Coxe, Terry Young, Paul E. Peppard, Laurel A. Finn, Ruth M. Benca Jan 2010

Prospective Associations Of Insomnia Markers And Symptoms With Depression, Mariana Szklo-Coxe, Terry Young, Paul E. Peppard, Laurel A. Finn, Ruth M. Benca

Community & Environmental Health Faculty Publications

Whether insomnia, a known correlate of depression, predicts depression longitudinally warrants elucidation. The authors examined 555 Wisconsin Sleep Cohort Study participants aged 33-71 years without baseline depression or antidepressant use who completed baseline and follow-up overnight polysomnography and had complete questionnaire-based data on insomnia and depression for 1998-2006. Using Poisson regression, they estimated relative risks for depression (Zung scale score >= 50) at 4-year (average) follow-up according to baseline insomnia symptoms and polysomnographic markers. Twenty-six participants (4.7%) developed depression by follow-up. Having 3-4 insomnia symptoms versus none predicted depression risk (age-, sex-, and comorbidity-adjusted relative risk (RR) = 3.2, 95% …


Robustness Of The Healthcare Utilization Results From The Rotavirus Efficacy And Safety Trial (Rest) Evaluating The Human-Bovine (Wc3) Reassortant Pentavalent Rotavirus Vaccine (Rv5), Robbin Itzler, Gary Koch, David O. Matson, Leif Gothefors, Pierre Van Damme, Mark J. Dinubile, Penny M. Heaton Jan 2010

Robustness Of The Healthcare Utilization Results From The Rotavirus Efficacy And Safety Trial (Rest) Evaluating The Human-Bovine (Wc3) Reassortant Pentavalent Rotavirus Vaccine (Rv5), Robbin Itzler, Gary Koch, David O. Matson, Leif Gothefors, Pierre Van Damme, Mark J. Dinubile, Penny M. Heaton

Community & Environmental Health Faculty Publications

Background: The Rotavirus Efficacy and Safety Trial was a placebo-controlled Phase III study that evaluated the safety and efficacy of a three-dose pentavalent rotavirus vaccine (RV5) including its effect on healthcare utilization for rotavirus gastroenteritis (RVGE). The per-protocol (PP) analyses, which counted events occurring 14 days after dose 3 among infants without protocol violations, have already been published. This paper evaluates the consistency of the healthcare utilization results based on the modified intention to treat (MITT) analyses with the PP analyses. The MITT analyses include all infants receiving at least one dose of vaccine or placebo and follow-up begins after …


Effluent Organic Nitrogen (Eon): Bioavailability And Photochemical And Salinity-Mediated Release, Deborah A. Bronk, Quinn N. Roberts, Marta P. Sanderson, Elizabeth A. Canuel, Patrick G. Hatcher, Rajaa Mesfioui, Katherine C. Filippino, Margaret R. Mulholland, Nancy G. Love Jan 2010

Effluent Organic Nitrogen (Eon): Bioavailability And Photochemical And Salinity-Mediated Release, Deborah A. Bronk, Quinn N. Roberts, Marta P. Sanderson, Elizabeth A. Canuel, Patrick G. Hatcher, Rajaa Mesfioui, Katherine C. Filippino, Margaret R. Mulholland, Nancy G. Love

Chemistry & Biochemistry Faculty Publications

The goal of this study was to investigate three potential ways that the soluble organic nitrogen (N) fraction of wastewater treatment plant (WWTP) effluents, termed effluent organic N (EON), could contribute to coastal eutrophication - direct biological removal, photochemical release of labile compounds, and salinity-mediated release of ammonium (NH4+). Effluents from two WWTPs were used in the experiments. For the bioassays, EON was added to water from four salinities (∼0 to 30) collected from the James River (VA) in August 2008, and then concentrations of N and phosphorus compounds were measured periodically over 48 h. Bioassay results, based …


Electric Pulses To Prepare Feeder Cells For Sustaining And Culturing Of Undifferentiated Embryonic Stem Cells, Lauren M. Browning, Tao Huang, Xiao-Hong Nancy Xu Jan 2010

Electric Pulses To Prepare Feeder Cells For Sustaining And Culturing Of Undifferentiated Embryonic Stem Cells, Lauren M. Browning, Tao Huang, Xiao-Hong Nancy Xu

Chemistry & Biochemistry Faculty Publications

Current challenges in embryonic-stem-cell (ESC) research include inability of sustaining and culturing of undifferentiated ESCs over time. Growth-arrested feeder cells are essential to the culture and sustaining of undifferentiated ESCs, and they are currently prepared using gammaradiation and chemical inactivation. Both techniques have severe limitations. In this study, we developed a new, simple and effective technique (pulsed-electric-fields, PEFs) to produce viable growth-arrested cells (RTS34st) and used them as high-quality feeder cells to culture and sustain undifferentiated zebrafish ESCs over time. The cells were exposed to 25 sequential 10- nanosecond-electric-pulses (10nsEPs) of 25, 40 and 150 kV/cm with 1s pulse interval, …


Sequence And Structural Analysis Of The Chitinase Insertion Domain Reveals Two Conserved Motifs Involved In Chitin Binding, Hai Li, Lesley H. Greene Jan 2010

Sequence And Structural Analysis Of The Chitinase Insertion Domain Reveals Two Conserved Motifs Involved In Chitin Binding, Hai Li, Lesley H. Greene

Chemistry & Biochemistry Faculty Publications

Background: Chitinases are prevalent in life and are found in species including archaea, bacteria, fungi, plants, and animals. They break down chitin, which is the second most abundant carbohydrate in nature after cellulose. Hence, they are important for maintaining a balance between carbon and nitrogen trapped as insoluble chitin in biomass. Chitinases are classified into two families, 18 and 19 glycoside hydrolases. In addition to a catalytic domain, which is a triosephosphate isomerase barrel, many family 18 chitinases contain another module, i.e., chitinase insertion domain. While numerous studies focus on the biological role of the catalytic domain in chitinase activity, …