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Interactions Between Metabolism And Growth Can Determine The Co-Existence Of Staphylococcus Aureus And Pseudomonas Aeruginosa, Camryn Pajon, Marla C. Fortoul, Gabriela Diaz-Tang, Estefania Marin Meneses, Ariane R. Kalifa, Elinor Sevy, Taniya Mariah, Brandon Toscan, Maili Marcelin, Daniella M. Hernandez, Melissa M. Marzouk, Allison J. Lopatkin, Omar T. Eldakar, Robert Smith Apr 2023

Interactions Between Metabolism And Growth Can Determine The Co-Existence Of Staphylococcus Aureus And Pseudomonas Aeruginosa, Camryn Pajon, Marla C. Fortoul, Gabriela Diaz-Tang, Estefania Marin Meneses, Ariane R. Kalifa, Elinor Sevy, Taniya Mariah, Brandon Toscan, Maili Marcelin, Daniella M. Hernandez, Melissa M. Marzouk, Allison J. Lopatkin, Omar T. Eldakar, Robert Smith

Biology Faculty Articles

Most bacteria exist and interact within polymicrobial communities. These interactions produce unique compounds, increase virulence and augment antibiotic resistance. One community associated with negative healthcare outcomes consists of Pseudomonas aeruginosa and Staphylococcus aureus. When co-cultured, virulence factors secreted by P. aeruginosa reduce metabolism and growth in S. aureus. When grown in vitro, this allows P. aeruginosa to drive S. aureus toward extinction. However, when found in vivo, both species can co-exist. Previous work has noted that this may be due to altered gene expression or mutations. However, little is known about how the growth environment could influence the …

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Age And Growth For Three Members Of The Family Gempylidae: Escolar (Lepidocybium Flavobrunnuem), Oilfish (Ruvettus Pretiosus), And Snake Mackerel (Gempylus Serpens), Sydney N. Daniels Apr 2023

Age And Growth For Three Members Of The Family Gempylidae: Escolar (Lepidocybium Flavobrunnuem), Oilfish (Ruvettus Pretiosus), And Snake Mackerel (Gempylus Serpens), Sydney N. Daniels

All HCAS Student Capstones, Theses, and Dissertations

Escolar, Lepidocybium flavobrunnuem (Smith, 1849), Oilfish, Ruvettus pretiosus (Cocco, 1829), and Snake Mackerel, Gempylus serpens (Cuvier, 1829) belong to the family Gempylidae and are bycatch of the tuna-targeting pelagic longline fishery. There is limited know life-history information on these mesopelagic fishes, especially regarding growth rates. Age estimates were assigned by counting pairs of increment bands formed on the sagittal otoliths of Escolar (n = 133), Oilfish (n = 49), and Snake Mackerel (n = 46) collected between 2007 and 2022. Marginal increment analyses were used to validate age estimates and periodicity of increment formation, but no significant trends were observed …

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The Potential For Top-Down Control Of The Corallivorous Gastropod Coralliophila Galea And Its Effect On Coral Reef Ecosystems, Tanya Y. Kamerman Apr 2023

The Potential For Top-Down Control Of The Corallivorous Gastropod Coralliophila Galea And Its Effect On Coral Reef Ecosystems, Tanya Y. Kamerman

All HCAS Student Capstones, Theses, and Dissertations

Corallivores are understood to be ecologically important. However, their effects on reef ecosystems are difficult to distinguish from the multiple anthropogenic stressors currently affecting reefs. The corallivorous muricid snail, Coralliophila galea, has been documented to have a strong negative impact on Caribbean coral reefs, including curtailing reef recovery following other stressors. Although the basic biology of C. galea is relatively well understood, the limited information on its predators prevents a complete understanding of predator-snail-coral relationships, which limits proper protection and conservation of coral reef ecosystems. To determine the impact predators of C. galea have on coral reef ecosystems, I assessed …

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The Frequency And Relationships Of Frailty Markers In Older Populations With Low Health Literacy, Nikhil Bhave, Neil Patel, Rosemary Davenport, Michael Simonson, Raymond Ownby Apr 2023

The Frequency And Relationships Of Frailty Markers In Older Populations With Low Health Literacy, Nikhil Bhave, Neil Patel, Rosemary Davenport, Michael Simonson, Raymond Ownby

InterLACE Research Showcase

No abstract provided.

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Development Of Models Of Alzheimer's Disease Progression Using Longitudinal Patient Data, Taravet Ghafourian, Benedict Albensi, Vivek Patel Apr 2023

Development Of Models Of Alzheimer's Disease Progression Using Longitudinal Patient Data, Taravet Ghafourian, Benedict Albensi, Vivek Patel

InterLACE Research Showcase

No abstract provided.

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The Role Of Long-Noncoding Rna Caren In Regulating Cardiac Cell Survival In Response To Ketogenic Diet, Narasimman Gurusamy, Natalia Noto, Zachary Lawrence, Yazmin Restrepo, Shalet James, Iliana Uribe, Ariana Hernandez, Robert Speth, Lisa Robison Apr 2023

The Role Of Long-Noncoding Rna Caren In Regulating Cardiac Cell Survival In Response To Ketogenic Diet, Narasimman Gurusamy, Natalia Noto, Zachary Lawrence, Yazmin Restrepo, Shalet James, Iliana Uribe, Ariana Hernandez, Robert Speth, Lisa Robison

InterLACE Research Showcase

No abstract provided.

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Sex Differences In The Physiological And Cognitive-Behavioral Effects Of High Fat And Ketogenic Diets In Mice, Lisa Robison, Zachary Lawrence, Shalet James, Natalia Noto, Yazmin Restropo, Iliana Uribe, Ariana Hernandez, Eleanor Wind, Blanche Tamiya, Victoria Pulido-Correa, Meha Pandaya, Robert Speth Apr 2023

Sex Differences In The Physiological And Cognitive-Behavioral Effects Of High Fat And Ketogenic Diets In Mice, Lisa Robison, Zachary Lawrence, Shalet James, Natalia Noto, Yazmin Restropo, Iliana Uribe, Ariana Hernandez, Eleanor Wind, Blanche Tamiya, Victoria Pulido-Correa, Meha Pandaya, Robert Speth

InterLACE Research Showcase

No abstract provided.

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Highly Antigenic Novel Soluble Hiv-1 Clade C 1086.C Env Trimer Vaccine Candidate, Mohammad Golam Sabbir, Alexander Bontempo, Mark Cayabyab Apr 2023

Highly Antigenic Novel Soluble Hiv-1 Clade C 1086.C Env Trimer Vaccine Candidate, Mohammad Golam Sabbir, Alexander Bontempo, Mark Cayabyab

InterLACE Research Showcase

No abstract provided.

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Therapeutic Effects Of Medicinal Mushrooms On Gastric, Breast, And Colorectal Cancer: A Scoping Review., Amit Dan, Robyn Swain, Seigna Belonce, Robin J. Jacobs Apr 2023

Therapeutic Effects Of Medicinal Mushrooms On Gastric, Breast, And Colorectal Cancer: A Scoping Review., Amit Dan, Robyn Swain, Seigna Belonce, Robin J. Jacobs

HPD Articles

Cancer is the leading cause of mortality globally. With anticancer medications causing severe adverse effects, understanding the role of alternative and efficacious anticancer treatments with minimal or no side effects can be beneficial. Edible mushrooms have been associated with certain health benefits and exhibit a broad range of pharmacological activities, including anti-inflammatory and immunomodulating activities. The anticancer potential of different mushrooms is now being tested. The goal of this scoping review was to discuss the most recent and available evidence on the therapeutic uses of medicinal mushrooms in cancer treatment, specifically those cancers with some of the highest mortality rates …

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Exploring The Dynamics Of Negotiating Everyday Sexism In India: A Daily Diary Study, Sudha Shashwati, Parul Gupta, Preeti Kapur Apr 2023

Exploring The Dynamics Of Negotiating Everyday Sexism In India: A Daily Diary Study, Sudha Shashwati, Parul Gupta, Preeti Kapur

The Qualitative Report

This study was undertaken to investigate the negotiation of everyday sexism encountered by college going young adult women in India in an urban context. An open-ended daily diary form was constructed, and 185 such forms were filled by 58 women enrolled in various colleges of a central university located in Delhi, India. These were analysed by content analysis with the help of NVivo software with a focus on target and type of sexism reported as well as response to sexist incident faced. The findings of this study reveal that participants chose inaction (53%) more than confronting sexism (47%), and reasons …

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The Current - Volume 33 Issue 9, Nova Southeastern University Apr 2023

The Current - Volume 33 Issue 9, Nova Southeastern University

Student Newspapers

No abstract provided.

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Decontamination And Annotation Of The Draft Genome Sequence Of The Oomycete Lagenidium Giganteum Arsef 373, William R. Morgan, Aurelien Tartar Apr 2023

Decontamination And Annotation Of The Draft Genome Sequence Of The Oomycete Lagenidium Giganteum Arsef 373, William R. Morgan, Aurelien Tartar

Biology Faculty Articles

Scaffolds of a previously published Lagenidium giganteum ARSEF 373 genome assembly found at GenBank were filtered to remove contaminating sequences. Genome annotation of the 437 scaffolds (total length, 56.2 MB; GC content, 58.8%) with confirmed L. giganteum sequences identified 13,069 potential protein-coding genes, encoding at least 737 predicted secreted proteins and .100 putative translocated effectors

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A Voting-Based Machine Learning Approach For Classifying Biological And Clinical Datasets., Negar Hossein-Nezhad Daneshvar, Yosef Masoudi-Sobhanzadeh, Yadollah Omidi Apr 2023

A Voting-Based Machine Learning Approach For Classifying Biological And Clinical Datasets., Negar Hossein-Nezhad Daneshvar, Yosef Masoudi-Sobhanzadeh, Yadollah Omidi

HPD Articles

BACKGROUND: Different machine learning techniques have been proposed to classify a wide range of biological/clinical data. Given the practicability of these approaches accordingly, various software packages have been also designed and developed. However, the existing methods suffer from several limitations such as overfitting on a specific dataset, ignoring the feature selection concept in the preprocessing step, and losing their performance on large-size datasets. To tackle the mentioned restrictions, in this study, we introduced a machine learning framework consisting of two main steps. First, our previously suggested optimization algorithm (Trader) was extended to select a near-optimal subset of features/genes. Second, a …

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Disruption, Transformation, Resilience, And Hope: The Experience Of A Belizean Community During Covid-19 Lockdown, Jean D. Kirshner Dr. Apr 2023

Disruption, Transformation, Resilience, And Hope: The Experience Of A Belizean Community During Covid-19 Lockdown, Jean D. Kirshner Dr.

The Qualitative Report

This qualitative research explored the lived experience of teachers, school administrators, parents, and children in Belize, Central America during the COVID-19 lockdown. Through field notes, correspondence, and interviews, a narrative approach was leveraged to convey the impact of two years away from classrooms and from each other. Both the trauma and loss of this disruption on global literacy, along with three forces that nourished the capacity for resilience, were examined.

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Editorial To The Ijms Special Issue On Sglt2 Inhibitors Vol. 1, Anastasios Lymperopoulos Apr 2023

Editorial To The Ijms Special Issue On Sglt2 Inhibitors Vol. 1, Anastasios Lymperopoulos

HPD Articles

No abstract provided.

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Accommodations Needed For Asd Patients During Dental Care, Krystal Eischen Olsen Apr 2023

Accommodations Needed For Asd Patients During Dental Care, Krystal Eischen Olsen

Undergraduate Student Symposium

This project aimed to investigate caregiver perspective regarding dental provider care for visits for their child[ren] with autism spectrum disorder (ASD). ASD is a developmental disorder that affects communication, sensory processing, and behavior. ASD can cause problems regarding oral health care and treatments due to the overwhelming sensations experienced by the patient, resulting in refusal behaviors regarding prevention, maintenance, diagnosis, and treatment of oral health care needs (Zhou et al., 2020). Dental providers aren’t extensively trained on treatment or support techniques recommended for this population, leading to a drop-off in patient care and a lack of caregiver training or support …

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A Review Of Healthcare-Related Decisions Faced By Women At Risk For Hereditary Breast Cancer, Rathika Manikandan, Ilan Nedjar Apr 2023

A Review Of Healthcare-Related Decisions Faced By Women At Risk For Hereditary Breast Cancer, Rathika Manikandan, Ilan Nedjar

Undergraduate Student Symposium

Hereditary breast cancer is defined as cancer that results from pathogenic mutations that are generationally inherited. In the U.S., hereditary cancer accounts for 5-10% of all cancer cases. Furthermore, approximately 264,000 newly diagnosed breast cancer cases are linked to pathogenic mutations. Pathogenic mutations in BRCA1, BRCA2, PALB2, and other genes are linked to a higher lifetime risk of breast cancer and ovarian cancer; women with these pathogenic mutations have lifetime risk of breast cancer up to 85% and lifetime risk of ovarian cancer up to 54% . Previvors are defined as individuals with an identified pathogenic mutation prior to a …

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A Review Of Treatment Options For Women Facing Hereditary Breast Cancer, Ilan Nedjar, Rathika Manikandan Apr 2023

A Review Of Treatment Options For Women Facing Hereditary Breast Cancer, Ilan Nedjar, Rathika Manikandan

Undergraduate Student Symposium

BRCA1 and BRCA2 are tumor suppressor genes, which produce proteins that aid repair damaged DNA. Women who carry a pathogenic mutation in BRCA1/BRCA2 genes have an increased risk of developing breast cancer. Furthermore, BRCA1/BRCA2 pathogenic mutations are associated with more aggressive breast cancer types (i.e., triple negative) and higher recurrence rates (10.5%) than for breast cancer of non-carrier patients. Consequently, BRCA1+/BRCA2+ breast cancer patients require a specialized treatment approach. The objective of this literature review is to summarize the various treatment options offered to BRCA1+/BRCA2+ breast cancer patients. Peer reviewed articles were found through multiple databases such as PubMed and …

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A Simple Method To Assess Porphyrin Basicity Using Competition Studies, Pranav Madadi, Ofek Gur, Ayush Desai Apr 2023

A Simple Method To Assess Porphyrin Basicity Using Competition Studies, Pranav Madadi, Ofek Gur, Ayush Desai

Undergraduate Student Symposium

Competition studies of three freebase porphyrins (H2OEP, H2OETPP, and H2TPP) were carried to assess their basicities. These porphyrins were selected because they are a good representation of natural occurring ones. In each experiment, the resultant UV-vis spectra were obtained by mixing and analyzing two porphyrins in a double-sided cuvette in which one was protonated using either trifluoroacetic acid (TFA) or hydrochloric acid (HCl) while the other was kept as a freebase. After mixing, the two porphyrins “compete” available protons, thus the most basic of them will acquire most of the protons. By adjusting the ratios of dications and freebases we …

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A Search For A Solution To Antibiotic-Resistance: Uncovering Phage From Soil Samples That Bind To A Type Iii Secretion System Of Yersinia Pestis, Shruti Patel, Ritika Vonguru, Kenya Reid, Jewel Mousa, Megha Kurian Apr 2023

A Search For A Solution To Antibiotic-Resistance: Uncovering Phage From Soil Samples That Bind To A Type Iii Secretion System Of Yersinia Pestis, Shruti Patel, Ritika Vonguru, Kenya Reid, Jewel Mousa, Megha Kurian

Undergraduate Student Symposium

The rise of antibiotic-resistant bacteria has recently become a major global health concern, requiring new methods to successfully combat these highly resistant microbes. One promising alternative to traditional antibiotics is phage therapy, where bacteriophages (viruses that infect bacteria) are utilized to target and kill bacteria. This study primarily focuses on discovering phages that are effective against Yersinia pestis (Y. pestis), the bacteria responsible for bubonic and pneumonic plague. One distinctive aspect of Y. pestis is its utilization of a type III secretion system (T3SS), a needle-like structure used to inject host cells with toxins that lead to infection. …

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Acute Toxicity Study Of Novel Melanoma Actives In Mice, Trisha Seal, Samaya Danthurthy Apr 2023

Acute Toxicity Study Of Novel Melanoma Actives In Mice, Trisha Seal, Samaya Danthurthy

Undergraduate Student Symposium

Although there have been promising advances in melanoma drug discovery, the average overall survival of patients with late-stage metastatic melanoma is approximately 3 years, which suggests a need for identifying new melanoma targets. We previously reported a discovery of melanoma actives acting via binding and down regulating human nuclear ribonuclear protein H1/H2 (hnRNP H1/H2), which is a novel target with unknown toxicity. Therefore, the aim of this study was to study the safety of novel anti-melanoma compounds 2155-14 and 2155-18 in mice. The methodology of the study involved injecting male and female Balb/C mice three times a week for three …

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An Impartial Supreme Court? Evaluating The Role Of Public Opinion In Supreme Court Rulings, Alexis Lass Apr 2023

An Impartial Supreme Court? Evaluating The Role Of Public Opinion In Supreme Court Rulings, Alexis Lass

Undergraduate Student Symposium

Susceptibility to public opinion is a phenomena faced by most political leaders, whether that be in City Halls or the United States’ Senate. Regardless, when separation of powers was conceptualized and the Supreme Court of the United States was created, the intent was to have a particular branch that didn’t make the law, but interpreted it, impartially, with a lack of partisanship opinion. In recent years, researchers have noticed a pattern of Supreme Court rulings aligning perfectly with public opinion, making field experts and citizens alike, question the integrity of the institution. The current study seeks to better understand the …

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Are Students In Broward County, Fl, Who Get Less Sleep More Likely To Experience Depressive Symptoms?, Kelly Nyman, Alissa Lopez, Lauren Herrera Apr 2023

Are Students In Broward County, Fl, Who Get Less Sleep More Likely To Experience Depressive Symptoms?, Kelly Nyman, Alissa Lopez, Lauren Herrera

Undergraduate Student Symposium

It is commonly known that sleep can significantly affect overall health in both physical and mental states, but can getting less sleep be an attributing factor to high school students experiencing symptoms of depression? In this study, we will determine whether less sleep is associated with feelings of sadness or hopelessness which are common symptoms of depression. Finding a link between the two could allow us to implement sleep education programs that would lower rates of depression in high school students. Using data collected from the 2019 YRBSS from Broward County, Florida, data was run comparing high school students who …

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An Examination Of The Social Reponse Of Children With Autism, Shriya Reddy, Shreeya Patel Apr 2023

An Examination Of The Social Reponse Of Children With Autism, Shriya Reddy, Shreeya Patel

Undergraduate Student Symposium

Children with Autism Spectrum Disorder (ASD) lack the ability to engage with others and make correct social predictions. Therefore, they misinterpret cues and exhibit incorrect social responses. The study’s aim was to compare the response of children with neurotypical development and children with ASD when presented with a friendly social interaction stimulus. Neurotypical children and children with ASD were recruited from public events and educational programs. Data were collected using Tobii Pro Nano eye-tracking device to measure eye movement while children’s autism risk was assessed with the MCHAT tool. Eye-tracking data were analyzed using Tobii Pro lab and statistical data …

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An Optimal Strategy For Using Mixture-Based Combinatorial Library Data To Find T-Cell Epitopes, Sofia Celis Apr 2023

An Optimal Strategy For Using Mixture-Based Combinatorial Library Data To Find T-Cell Epitopes, Sofia Celis

Undergraduate Student Symposium

Positional scanning libraries are well established in their use for peptide sequence identification and binding site optimization. Their use in identifying T cell stimulatory peptides has also previously been explored. Here we present a retrospective analysis on the results of mixture based positional scanning libraries of T-cell stimulatory peptides done before 2019 in order to identify an optimal strategy for using mixture based combinatorial library data to find T cell epitopes. The screening of positional scanning libraries against CD4+ and CD8+ T cell clones was analyzed using biometrical analysis approaches of various kinds in order to evaluate their relative effectiveness …

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Analysis Of Errors In Ecgs Data Captured By Patients Using At-Home Device Compared To Qualified Healthcare Professionals, Colin Pulickathadam Apr 2023

Analysis Of Errors In Ecgs Data Captured By Patients Using At-Home Device Compared To Qualified Healthcare Professionals, Colin Pulickathadam

Undergraduate Student Symposium

Cardiovascular Diseases (CVDs) are a leading cause of death worldwide, accounting for 17.3 million deaths per year. General at-home care has been proven to improve patient outcomes and decrease hospitalization rates. The purpose of this presentation is to present pilot data results comparing the electrocardiogram (ECG) readability from patients and their caregivers, who conducted at-home ECGs in the experimental group, versus data on ECG readability from patients at routine office visits, where a qualified healthcare professional takes the ECG readings as the control group. The pilot data involves a sample of 20 patients’ 105 ECG records analyzed using SPSS with …

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Assessing Social Humanoid Interaction Across Levels Of Trust, Persuasion, And Empathy, Expert Panel Survey Validation, Nitya Alaparthy, Brigitte Wodrich Apr 2023

Assessing Social Humanoid Interaction Across Levels Of Trust, Persuasion, And Empathy, Expert Panel Survey Validation, Nitya Alaparthy, Brigitte Wodrich

Undergraduate Student Symposium

Social humanoids present a wide range of opportunities regarding interactions with humans with the purpose of using artificial intelligence systems to aid with day-to-day activities. Humanoids can be programmed to provide high levels of intelligence for task fulfillment such as assisting caregivers/patients, washing human limbs autonomously, assisting with lift-and-transfer patients, and even delivering blood samples. Additional tasks include carrying objects, opening doors, operating telehealth consultations, providing demonstrations, coaching, and serving companionship for any patients. Researchers are assessing the interactions between social humanoids and patients across levels of trust, persuasion, and empathy. This project aims to explore such interactions in the …

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Assessment Of Brain Function And Putting Performance Of Collegiate Golfers, Marissa Bonsangue Apr 2023

Assessment Of Brain Function And Putting Performance Of Collegiate Golfers, Marissa Bonsangue

Undergraduate Student Symposium

Electroencephalography (EEG) is a noninvasive method for assessing brain activity. Significant correlation has been indicated between performance outcome and brain wave measures. During a putting sequence, a golfer requires significant focus to successfully perform the skill, therefore certain brain wave frequencies are more apparent. Male and female golfers (n = 11) from a National Collegiate Athletic Association (NCAA) Division II Program were asked to complete 10 putts at 5 varied hole distances (total- 50 putts) on an outdoor putting surface. EEG was recorded in 4-second epochs and assessed to the extent of power spectral density (PSD). Each epoch was classified …

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Assessment Of Gopher Tortoise (Gopherus Polyphemus) Activity And Faunal Diversity Associated With Tortoise Burrows Using Trail Cameras At Three South Florida Natural Areas, Reginald Kempson Iii, Indaya Byer, Grace Mikus, Emma Pinard, Hiba Ali Apr 2023

Assessment Of Gopher Tortoise (Gopherus Polyphemus) Activity And Faunal Diversity Associated With Tortoise Burrows Using Trail Cameras At Three South Florida Natural Areas, Reginald Kempson Iii, Indaya Byer, Grace Mikus, Emma Pinard, Hiba Ali

Undergraduate Student Symposium

The gopher tortoise (Gopherus polyphemus) is a protected keystone species found in our area. The excavated burrows they create are shelter for hundreds of commensal species during wildfires and extreme heat. Nine motion-activated trail cameras (three at each site) were mounted outside burrows in three local natural areas (Fern Forest (FF), Military Trail (MT), and Deerfield Island Park (DI)). Pictures and videos of animals were recorded at burrow entrances intermittently over an 11-month period between January 2022 and November 2022. Cameras were left in the field between 15-30 days at a time before retrieval and exchange of SD …

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Association Between School Mental Health And Suicide Prevention Education Policies And Adolescent Suicide Attempts, Sonia Rao Apr 2023

Association Between School Mental Health And Suicide Prevention Education Policies And Adolescent Suicide Attempts, Sonia Rao

Undergraduate Student Symposium

In the past ten years, the intensity and complexity of declining mental health has been on the rise among high school students. This increasing trend may impact the rates at which students consider or even attempt suicide. In 2019, 10,520 of high school students in the United States reported attempting suicide out of which 8,749 (83.2%) needed medical attention. The current ecological study investigates the association between state-level mental and emotional health education and suicide prevention education policies to suicide attempts among high school students. Secondary data collected from the CDC’s Youth Behavior Risk Surveillance System (YRBSS) and National Association …

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