Digital Commons Network^™

Com Outlook Summer 2013, College Of Osteopathic Medicine

COM Outlook

No abstract provided.

Guidance On Performing Focused Ethnographies With An Emphasis On Healthcare Research, Gina M.A Higginbottom, Jennifer J. Pillay, Nana Y. Boadu

The Qualitative Report

Focused ethnographies can have meaningful and useful application in primary care, community, or hospital healthcare practice, and are often used to determine ways to improve care and care processes. They can be pragmatic and efficient ways to capture data on a specific topic of importance to individual clinicians or clinical specialties. While many examples of focused ethnographies are available in the literature, there is a limited availability of guidance documents for conducting this research. This paper defines focused ethnographies, locates them within the ethnographic genre, justifies their use in healthcare research, and outlines the methodological processes including those related to …

Antioxidant Treatment Regulates The Humoral Immune Response During Acute Viral Infection, Katie E. Crump, P. Kent Langston, Sujana Rajkarnikar, Jason M. Grayson

Biology Faculty Articles

Generation of reactive oxygen intermediates (ROI) following antigen receptor ligation is critical to promote cellular responses. However, the effect of antioxidant treatment on humoral immunity during a viral infection was unknown. Mice were infected with lymphocytic choriomeningitis virus (LCMV) and treated with Mn(III)tetrakis(4-benzoic acid)porphyrin chloride (MnTBAP), a superoxide dismutase mimetic, from days 0 to 8 postinfection. On day 8, at the peak of the splenic response in vehicle-treated mice, virus-specific IgM and IgG antibody-secreting cells (ASC) were decreased 22- and 457-fold in MnTBAP-treated animals. By day 38, LCMV-specific IgG ASC were decreased 5-fold in the bone marrow of drug-treated mice, …

College Of Osteopathic Medicine Entering Class 2013, Nova Southeastern University

Health Professions Divisions Course Catalogs and Course Descriptions

No abstract provided.

Com Outlook Winter 2013, College Of Osteopathic Medicine

COM Outlook

No abstract provided.

Host Genomic Influences On Hiv/Aids, Stephen J. O'Brien, Sher L. Hendrickson

Biology Faculty Articles

The AIDS era has seen multiple advances in the power of genetics research; scores of host genetic protective factors have been nominated and several have translated to the bedside. We discuss how genomics may inform HIV/AIDS prevention, treatment and eradication.

The Principal Genetic Determinants For Nasopharyngeal Carcinoma In China Involve The Hla Class I Antigen Recognition Groove, Minzhong Tang, J. A. Lautenberger, Xiaojiang Gao, Efe Sezgin, Sher L. Hendrickson, Jennifer L. Troyer, Victor A. David, Li Guan, Carl Mcintosh, Xiuchan Guo, Yuming Zheng, Jian Liao, Hong Deng, Michael Malasky, Bailey Kessing, Cheryl Winkler, Mary Carrington, Guy De The, Yi Zeng, Stephen J. O'Brien

Biology Faculty Articles

Nasopharyngeal carcinoma (NPC) is an epithelial malignancy facilitated by Epstein-Barr Virus infection. Here we resolve the major genetic influences for NPC incidence using a genome-wide association study (GWAS), independent cohort replication, and high-resolution molecular HLA class I gene typing including 4,055 study participants from the Guangxi Zhuang Autonomous Region and Guangdong province of southern China. We detect and replicate strong association signals involving SNPs, HLA alleles, and amino acid (aa) variants across the major histocompatibility complex-HLA-A, HLA –B, and HLA -C class I genes (P_{HLA-A-aa-site-62}= 7.4×10⁻²⁹; P _{HLA-B-aa-site-116}= 6.5×10⁻¹⁹; P _{HLA-C-aa-site-156} = 6.8×10 …

African American Women: The Face Of Hiv/Aids In Washington, Dc, Ndidiamaka N. Amutah

The Qualitative Report

In 2007, the estimated HIV and AIDS case rates among adult and adolescent African-American females in the United States was 60.6 per 100,000, as compared to 3.3 per 100,000 for adult and adolescent white American females. Women living with HIV or AIDS often face complex social problems that may inhibit them from accessing resources and healthcare services to assist them in coping with the disease. In-depth interviews and direct observations utilizing open-ended note taking were conducted at an HIV service provider’s office to determine the unique needs that develop because of these complex social issues, specifically among HIV positive women …

A Preliminary Qualitative Evaluation Of The Virginia Gold Quality Improvement Program, Gerald A. Craver, Amy K. Burkett

The Qualitative Report

Certified nursing assistants (CNAs) perform an important role in the long-term care system because they provide the majority of paid care to nursing facility residents. Unfortunately, annual CNA turnover often exceeds 100 percent nationally. Many factors account for this, including stressful working conditions, low pay, and limited benefits. The end result of high turnover is compromised continuity of care for residents, which often leads to poor quality and substandard care. In an effort to improve quality of care and staffing, the Virginia Department of Medical Assistance Services in 2009 implemented a pilot program, known as the Virginia Gold Quality Improvement …

2012-2013 Farquhar Forum, Farquhar College Of Arts And Sciences

The Farquhar Forum College Magazine

No abstract provided.

Com Outlook Summer 2012, College Of Osteopathic Medicine

COM Outlook

No abstract provided.

Assessment Of The Utilization Of Hiv Interventions By Sex Workers In Selected Brothels In Bangladesh: An Exploratory Study, Nafisa Lira Huq, Mahbub Elahi Chowdhury

The Qualitative Report

In this qualitative study of brothel-based Female Sex Workers (FSWs), the authors explored factors that influence safe sex practices of FSWs within an integrated HIV intervention. Qualitative methods, including focus group discussions (FGDs), in-depth interviews and key informant interviews were applied in four brothels in Bangladesh. Young and elderly FSWs, Sordarnis (Madams who own young FSWs and who may be either active or inactive sex workers themselves), program managers and providers were the participants for this study. Findings showed that condom use was high but not consistent among bonded FSWs (those who are under the control of a Sordarni) who …

The Current Volume 22 : Issue 19, Nova Southeastern University

Student Newspapers

No abstract provided.

Emerging Viruses In The Felidae: Shifting Paradigms, Stephen J. O'Brien, Jennifer L. Troyer, Meredith Brown, Warren E. Johnson, Agostinho Antunes, Melody E. Roelke, Jill Pecon-Slattery

Biology Faculty Articles

The domestic cat is afflicted with multiple viruses that serve as powerful models for human disease including cancers, SARS and HIV/AIDS. Cat viruses that cause these diseases have been studied for decades revealing detailed insight concerning transmission, virulence, origins and pathogenesis. Here we review recent genetic advances that have questioned traditional wisdom regarding the origins of virulent Feline infectious peritonitis (FIP) diseases, the pathogenic potential of Feline Immunodeficiency Virus (FIV) in wild non-domestic Felidae species, and the restriction of Feline Leukemia Virus (FeLV) mediated immune impairment to domestic cats rather than other Felidae species. The most recent interpretations indicate important …

A Preliminary Examination Of A Program That Provides Free Blood Glucose Testing Meters, And Subsidies On Test-Strips To Adult Diabetics, Cecil White

Abraham S. Fischler College of Education ETD Archive

This applied dissertation was designed to conduct a preliminary examination of the effects of the provision of free glucose testing meters, and test-strips subsidies on blood glucose control among diabetics. The study examined whether there was any impact on the frequency of testing, and whether there was a correlation between the frequency of testing and blood sugar control, as measured by HbA1c tests.

The researcher conducted a study of the program using a quasi-experimental design, and used the Glucose Monitoring Patient Questionnaire to compare the results between a test group and a control group of participants. Independent t tests were …

The Current Volume 22 : Issue 12, Nova Southeastern University

Student Newspapers

No abstract provided.

Aids Related Stigma In Social Relations: A Qualitative Study In Turkey, Aytul Kasapoglu, Elif Kus Saillard, Nilay Kaya, Feryal Turan

The Qualitative Report

The actual number of HIV/AIDS cases in Turkey is higher than the number of cases reported, and People Living with HIV (PLWHIV) may refrain from acknowledging their sickness or seeking help because of the stigma associated with HIV and fear of discrimination from their close friends, workmates, and even their families. In this paper we aim to explore HIV-positive people's relationships with significant others such as family members, friends, sexual partners, employers and health professionals in order to present the patients' perceptions about stigma and attitudes that lead to pro-social or anti-social behavior towards them. We carried out a qualitative …

Role Of Exonic Variation In Chemokine Receptor Genes On Aids: Ccrl2 F167y Association With Pneumocystis Pneumonia, Ping An, Rongling Li, Ji Ming Wang, Teizo Yoshimura, Munehisa Takahashi, Ram Samudralal, Stephen J. O'Brien, John Phair, James J. Goedert, Gregory D. Kirk, Jennifer L. Troyer, Efe Sezgin, Susan Buchbinder, Sharyne Donfield, George W. Nelson, Cheryl Winkler

Biology Faculty Articles

Chromosome 3p21–22 harbors two clusters of chemokine receptor genes, several of which serve as major or minor coreceptors of HIV-1. Although the genetic association of CCR5 andCCR2 variants with HIV-1 pathogenesis is well known, the role of variation in other nearby chemokine receptor genes remain unresolved. We genotyped exonic single nucleotide polymorphisms (SNPs) in chemokine receptor genes: CCR3, CCRL2, and CXCR6 (at 3p21) and CCR8 and CX3CR1 (at 3p22), the majority of which were non-synonymous. The individual SNPs were tested for their effects on disease progression and outcomes in five treatment-naïve HIV-1/AIDS natural history cohorts. In …

2011 Fall Farquhar Forum, Farquhar College Of Arts And Sciences

The Farquhar Forum College Magazine

No abstract provided.

Gm-Csf Production Allows The Identification Of Immunoprevalent Antigens Recognized By Human Cd4+ T Cells Following Smallpox Vaccination, Valeria A. Judkowski, Alcinette Bunying, Feng Ge, Jon R. Appel, Kingyee Law, Atima Sharma, Claudia Raja-Gabaglia, Patricia Norori, Radleigh Santos, Marc Giulianotti, Mark K. Slifka, Daniel C. Douek, Barney S. Graham, Clemencia Pinilla

Mathematics Faculty Articles

The threat of bioterrorism with smallpox and the broad use of vaccinia vectors for other vaccines have led to the resurgence in the study of vaccinia immunological memory. The importance of the role of CD4+ T cells in the control of vaccinia infection is well known. However, more CD8+ than CD4+ T cell epitopes recognized by human subjects immunized with vaccinia virus have been reported. This could be, in part, due to the fact that most of the studies that have identified human CD4+ specific protein-derived fragments or peptides have used IFN-γ production to evaluate vaccinia specific T cell responses. …

An Effective Pedagogical Approach To Understanding Qualitative And Quantitative Organic Chemistry By Using A Gas Chromatograph Mass Spectrometer, Sagir Patel

Undergraduate Student Symposium

One main objective of organic chemistry courses is to show students how much of a desired organic product is synthesized in the reaction mixture. Here, we report how a Gas Chromatography-Mass Spectrometry (GC-MS) instrument can be applied to a set of common organic chemistry experiments for identifying the main product, any minor product(s) and quantifying the product yield. GC-MS is a powerful analytical instrumentation tool capable of detecting, identifying and quantifying many volatile organic compounds. The GC-MS technique is routinely used in chemistry research and manufacturing laboratories. Despite its wide application in organic chemistry and ease of use, many colleges …

Analyzing Hotel Room Cleanliness On A Microscopic Level, Ahmad Khalid, Kodi Stevens

Undergraduate Student Symposium

The cost of a hotel room is usually correlated to the quality of the hotel room and the quality of services provided during one’s stay; e.g. the cleanliness of the room and the thoroughness of the cleaning staff. The cleaner a hotel is the more desirable it is. The goal of this experiment was to analyze hotel cleanliness at the microscopic level to determine if pathogenic micro-organisms were present. Samples were taken from telephones, toilet seats, remotes, toilet flushers, bath tubs and doorknobs from five different hotels and grown at room temperature on nutrient agar plates, counted and then isolated. …

A Final Truth: Based On The True Story Of A College Student Diagnosed With Hiv/Aids, Uyen-Linh Jackie Dao

Undergraduate Student Symposium

“A Final Truth: Based on the True Story of a College Student Diagnosed with HIV/AIDS” is a short film about a student living with HIV/AIDS. It is a dramatic retelling of a true story. The film touches on the social stigma of a person living with the disease, and the implications that the disease can have on friendship, sexual health, and college life. This story is told through the perspectives of a close group of college friends. One of the friends is living with HIV/AIDS and is unable to tell her friends in fear of rejection and judgment by her …

The Effect Of Thimerosal-Containing And Thimerosal-Free Pediatric Flu Vaccine On Gene Expression In Saccharomyces Cerevisiae, Christie Rubio

Undergraduate Student Symposium

Mercury-based preservatives including thimerosal, typically added to some vaccines, may pose health concerns as mercury toxicity has been implicated in many human diseases. In this study, microarray technology and reverse transcriptase-polymerase chain reaction (RT-PCR) were used to examine the potential effects of a typical dose of thimerosal-containing vaccine (TCV) or thimerosal-free (TFV) pediatric flu vaccine on gene expression in Saccharomyces cerevisiae, a model organism that shares roughly 30% of its genome with humans. Yeast were grown in three treatments: standard media (YEPD), YEPD plus TCV, and YEPD plus TFV. Microarray gene expression data were examined for variability both within …

The Effects Of Categorization On Memory, Logan Armstrong

Undergraduate Student Symposium

The purpose of this study was to explore the effects of categorization on our ability to remember events and objects. This is an important question because little research has tested the notion that the ability to categorize helps produce better memory. Morris & Baker-Ward (2007) studied a similar question when they examined whether having the vocabulary to describe an experience affected the ability to remember that experience. Specifically, they tested whether infants who had learned their colors prior to participating in an experiment involving different colored bubbles would recall the experiment better than those who learned the colors after the …

The Distribution Of Two Sea Pens (Pennatulidae) In The Sw Gulf Of California, Mexico With Reference To Predation, Angelica M. Garcia

Undergraduate Student Symposium

Sea pens (Pennatulidae) are sessile, benthic cnidarians that inhabit soft sediment, and rely on filter feeding to obtain energy. They have a central stalk (rachis) which contains secondary polyps for feeding. Since no previous data has been collected on their distribution, abundance or size in the SW Gulf of California, Mexico, benthic surveys were conducted at depths of 11.0 - 32.6 m near Isla San Fransiscito and El Pardito. Two species (Stylatula elongata and Ptilosarcus undulatus) were observed. The average height ± s.d. (tip to sediment surface) of S. elongata was 9.5 ± 3.8 cm (n=37) and was …

On Parmenides’ Reality, Nathaniel Dolan

Undergraduate Student Symposium

The treatment being submitted here for the Farquhar College of Arts and Sciences Undergraduate Student Symposium began quite simply in the form of a journal entry submitted as one of the required elements of Dr. Toscano’s Introduction to Philosophy (PHIL 1010) in the 2010 fall term. The professor’s review and critique of that original work (which was comparably brief compared to this final edition) produced remarks from Dr. Toscano that motivated me to reevaluate my own interpretations of the proposition on Reality put forth by Parmenides of Elea in the fifth century BCE. Having studied philosophy as a personal interest …

More Than Just A Memory, Sebastian Acosta-Nijamkin

Undergraduate Student Symposium

“More than just a memory” is a film about love and friendship. Ethan is confronted with a tough decision: whether to tell the girl he loves how he really feels, or whether to accept the fact that she loves someone else and that Ethan will only be a friend in her eyes. Throughout the film, Ethan is driving in a car, and flashbacks of the night where he chose to be just a friend keep entering his mind. That night he made a choice -- a choice that would change his life forever. The film is directed by Sebastian Acosta-Nijamkin.

Transcriptome Analysis Of Lagenidium Giganteum, Jennifer L. Grant

Undergraduate Student Symposium

Mosquitoes are carriers of numerous diseases for instance, malaria and west-Nile virus. Lagenidium giganteum is a parasitic organism during larval stage that infects and kills mosquitoes. In time, this could be proven to be useful in bioengineering to create an environmentally safe insecticide. Molecular research was performed in order to determine the imperative genes in Lagenidium giganteum that hinder the development in mosquito larvae. A culture of Lagenidium giganteum was used to extract RNA and initiate a transcriptome analysis. Large scale sequencing led to the annotation of 20,000 transcripts. PCR amplification was performed using a Qiagen PCR kit in order …

Cognitive Inhibition In Bilinguals Vs. Monolinguals, Juliana Acosta, Raquel Chocron, Jacqueline Pablos

Undergraduate Student Symposium

Bilingualism has been linked to enhanced cognitive abilities and these enhanced abilities are believed to be mediated by the same frontal lobe system that controls language output in bilinguals. Moreover, recent research suggests that this bilingual advantage may be moderated by degree of balance between the two languages such that those who are equally proficient in their two languages show the best performance on cognitive tasks compared to unbalanced bilinguals and monolinguals. For instance, results from one study revealed that balanced bilinguals showed significantly fewer errors on the Wisconsin Card Sorting Test (WCST) than unbalanced bilinguals. Thus, the purpose of …