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The Effect Of Y15 And Curcumin On The Ovarian Cancer Cell Line Ovcar3, Nicole Coelho, Amanda Ramnot Apr 2016

The Effect Of Y15 And Curcumin On The Ovarian Cancer Cell Line Ovcar3, Nicole Coelho, Amanda Ramnot

Undergraduate Student Symposium

Curcumin gives turmeric, a spice derived from Curcuma longa, its yellow color. Previous studies have reported that curcumin inhibits the proliferation of multiple cancer cell types, including ovarian, pulmonary, brain, and breast cancer through various pro-apoptotic mechanisms. In advanced ovarian cancer, focal adhesion kinase (FAK), a tyrosine kinase, is overexpressed and contributes to cancer aggression and resistance. 1,2,4,5-benzene tetraamine tetrahydrochloride (Y15) is an inhibitor of FAK and combining it with curcumin shows promise in reducing the FAK activity in ovarian cancer. Therefore, in the current study, the cytotoxic effect of Y15 and curcumin in combination and alone on the …

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The Impact Of Gender Inequality On Earnings Of Women In Stem Fields: Historical Evidence And Possible Solutions, Matthew Hoy, Teodora Suciu Apr 2016

The Impact Of Gender Inequality On Earnings Of Women In Stem Fields: Historical Evidence And Possible Solutions, Matthew Hoy, Teodora Suciu

Undergraduate Student Symposium

This study examines the current gender inequality in STEM fields, as well as its causes and some possible solutions. STEM–also known as the areas of science, technology, engineering, and math–are heavily male-dominated fields. The matter of gender inequality in these fields begins with gender separation during childhood and continues to the issue of the pay gap during adulthood. It is proven that currently women generate less capital than males in the same position in STEM fields, leading to a harsh divide between genders. Recent and relevant studies describing the statistics and explaining the reasons behind these gender and pay gaps …

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The Loss Of Modernism In Nazi Germany, Taylor Duggan Apr 2016

The Loss Of Modernism In Nazi Germany, Taylor Duggan

Undergraduate Student Symposium

Modernism in Germany was ultimately detested, ridiculed, and outlawed by Adolf Hitler in Nazi Germany but in turn was the movement that assured his position in power. In the year 1929, an opportunist and German Art Society organizer, Feistal-Rohmedar, designed the artistic revolution within Germany and first introduced the thought regarding the extermination of modern artwork. Between the years of 1933 and 1937, the Third Reich and the German Art Society were also on a mission to rid Germany of Modernism and it wasn’t until 1936 that Modernism was completely ruled out. The Third Reich believed that artistic manifestation and …

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Working Memory Capactiy And The Benefits Of Mental Imagery Practice On A Ring Toss Game, Kavan Thompson Apr 2016

Working Memory Capactiy And The Benefits Of Mental Imagery Practice On A Ring Toss Game, Kavan Thompson

Undergraduate Student Symposium

The goal of this experiment was to investigate how individual differences in working memory capacity affected an individuals’ ability to benefit from mental imaging. The main hypothesis for the experiment was that individuals with higher working memory capacity would benefit more from mental practice than individuals with lower working memory capacity. Subjects were placed in either a mental and physical practice group or a physical practice only group. The mental/physical practice group practiced a ring toss game for three minutes, then had five minutes of mentally visualizing a 25-point toss, followed by another two minutes of physical practice. The physical …

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How To Get The Word Out, Kathleen Bowman Apr 2016

How To Get The Word Out, Kathleen Bowman

Undergraduate Student Symposium

The survey, “How to get the Word Out”, was taken by 185 students of the NSU community at the end of April 2015. This survey was handed out as well as taken online. Thirty-six students took the online survey, while the other 149 students took the handout version. The surveys were collected from Parker, the UC, Flight Deck, and the Library Deli. The goal was to make sure to get a variety of different people represented in this data.

The purpose of this survey was to figure out a better way for student organizations to advertise on campus. The questions …

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Analyzing South Florida's Waterways For Lead Contamination, Megan Bruce Apr 2016

Analyzing South Florida's Waterways For Lead Contamination, Megan Bruce

Undergraduate Student Symposium

Periodic testing and analysis for lead contamination in surface waters is important to better prevent tragedies like the one currently happening in Flint, Michigan. For this project, water samples will be taken from various locations in South Florida, and the locations will be recorded using GPS coordinates listed as degrees, minutes, and seconds. The samples will then be analyzed for lead concentration using an Atomic Absorption Flame Spectrometer; the vales will be recorded in ppm. Finally, the concentrations of lead from environments that have little to no development will be compared to that of urban and rural locations. This type …

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Bacterial Analysis Of Skin Flora On Hands Throughout The Day, Leonor Sarria Apr 2016

Bacterial Analysis Of Skin Flora On Hands Throughout The Day, Leonor Sarria

Undergraduate Student Symposium

This project was part of an investigative report for Al Rojo Vivo’s “Amenaza Escondida” (“Hidden Threats”) on Telemundo. The television network’s team followed an individual as he carried on his daily activities. A sterile swab was used to test the objects being touched by the individual, as well as the individual’s hands after touching that object. The samples were placed on a nutrient agar plate and brought to us for incubation at 37 °C overnight. The goal of this study was to identify the bacterial changes on the hands of an individual as he goes about his daily activities. A …

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Biosorption Of Metal Ions By Neochloris Minuta And Neochloris Alveolaris Alga Grown In Regular And Nitrogen Depleted Media, Sara Rodriguez Apr 2016

Biosorption Of Metal Ions By Neochloris Minuta And Neochloris Alveolaris Alga Grown In Regular And Nitrogen Depleted Media, Sara Rodriguez

Undergraduate Student Symposium

Heavy metals are the most hazardous pollutants present in industrial and domestic waste water. The conventional methods for metal ions removal from wastewater are limited by technical and economical barriers, especially when concentration of metals in the wastewater is low (<100 ppm). Therefore the search and development of efficient and low-cost metal removal processes is of great importance. In this research project, two strains of algae Neochloris minuta and Neochloris alveolaris were grown in two different growth media: one with high nitrogen content (+N) and the other which was completely nitrogen depleted (-N). Nitrogen depletion increases the algal lipid content whereas a +N media would allow for the algae to synthesize more proteins. The dried algae strains were then mixed for 1 hour with metal …

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Changes In Coral (Pocillopora Damicornis) Population Structure In Concha De Perla Lagoon, Isabela Island, Galápagos Islands, Ecuador, Alexander Pich Apr 2016

Changes In Coral (Pocillopora Damicornis) Population Structure In Concha De Perla Lagoon, Isabela Island, Galápagos Islands, Ecuador, Alexander Pich

Undergraduate Student Symposium

Elevated sea surface temperatures associated with El Niño-Southern Oscillation (ENSO) can severely impact coral populations in the Galápagos Islands, Ecuador. During the 1982-83 event, 95-99% of reefbuilding corals bleached and died. This study examines if the onset of the 2015-2016 ENSO affected the important reef-building coral Pocillopora damicornis. The largest known population of this species in the Islands is found in the Concha de Perla lagoon on Isabela Island. It was first surveyed in 2012 and was visited again in 2015 to determine if colony size and coral condition (bleaching, paling, or mortality) changed. Underwater photographs were quantified for …

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Development Of A Method To Analyze Electronic Cigarette Liquid Solutions, Bendik Stenersen, Rebecca Nosal Apr 2016

Development Of A Method To Analyze Electronic Cigarette Liquid Solutions, Bendik Stenersen, Rebecca Nosal

Undergraduate Student Symposium

Electronic cigarettes have become increasingly popular in the last decade although there is minimal evidence to support their safety. The goal of this study is to develop a method to separate and analyze the contents of electronic cigarette liquid solutions. Various solutions of different nicotine concentrations were obtained from a commercial distributor. The e-liquid solutions were diluted to optimize analysis and separation. A method was established to separate the components of the solutions, and multiple chemical analysis tools were employed to collect and analyze the data.

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Comparison Of Living And Dead Populations Of The Fungiid Coral Cycloseris Curvata In The Galápagos Isalnds, Ecuador, Brandon Brulé Apr 2016

Comparison Of Living And Dead Populations Of The Fungiid Coral Cycloseris Curvata In The Galápagos Isalnds, Ecuador, Brandon Brulé

Undergraduate Student Symposium

This study compares living and dead populations of the rare fungiid coral, Cycloseris curvata, from two locations at opposite ends of the Galápagos Archipelago. Cycloseris is one of only two fungiid coral species in the Eastern Pacific, and occurs in isolated, patchy populations. The only known live population of this species in the Galápagos Islands is found at Devil’s Crown, Floreana Island at the southern end of the Archipelago. Additionally, dead skeletons were first observed in 2012 at Darwin Reef, 364 km north-northwest of the living population. Skeleton size was quantified from digital photographs using the program Coral Point …

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Effects And Success Of The Americans With Disabilities Act Of 1990 (Ada), Emily Lowry Apr 2016

Effects And Success Of The Americans With Disabilities Act Of 1990 (Ada), Emily Lowry

Undergraduate Student Symposium

On July 26, 1990, the Americans with Disabilities Act was signed by George H.W. Bush with the intent of prohibiting discrimination based on disability. It affects access to employment, state and local government programs and services; access to places of public accommodation such as businesses, transportation, and non-profit service providers, and telecommunications. This act was implemented to protect the rights and equality of the vast amount of disabled citizens in America. According to the Census Bureau, About 56.7 million people — 19 percent of the population — had a disability in 2010, according to a broad definition of disability. During …

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Fighting Thyroid Cancer, Rosie Khachatryan Apr 2016

Fighting Thyroid Cancer, Rosie Khachatryan

Undergraduate Student Symposium

“Fighting Thyroid Cancer” is a short film about my experience with thyroid cancer. The film was created to raise awareness regarding this kind of cancer, because it can go unnoticed for many years. With the use of my real life experience, as well as interviews from people close to me that have gone through the same things, I hope to help people with this disease know that it can get better. I want to encourage others to ask their doctor to see if they might have this disease, because I had no idea. The film is directed by Rosie Khachatryan.

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Frozen Brain Atlas: Individualized Brain Mapping For Receptor Autoradiography Analysis, Samantha Bergoine Apr 2016

Frozen Brain Atlas: Individualized Brain Mapping For Receptor Autoradiography Analysis, Samantha Bergoine

Undergraduate Student Symposium

The Frozen Brain Atlas provides students, educators, and scientists with a tool to further explore the architecture of the brain. Current brain atlases allow users to navigate sectioned brain tissue using histological staining; however, they fail to capture naturally visible structures post sectioning. Through immediate post sectioning image collection, the natural contrast of the brain reveals unique structural details that are rarely seen by traditional staining procedures. By utilizing indexing and interactive labeling, the Nova Southeastern University Frozen Brain Atlas will allow identification of brain regions when used as a correlative tool for modalities including receptor autoradiography, immunofluorescence, and other …

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Isolation Of Antibiotic Producing Microorganisms From Various Soil: The Everglades, Davie, And West Palm Beach, Antonina Bukatevych, Taura Khorramshahi, Nick Morgan Apr 2016

Isolation Of Antibiotic Producing Microorganisms From Various Soil: The Everglades, Davie, And West Palm Beach, Antonina Bukatevych, Taura Khorramshahi, Nick Morgan

Undergraduate Student Symposium

The Small World Initiative is combating the decrease in antibiotic effectiveness. The majority of antibiotics in current use originate from soil dwelling bacteria. The soil samples were obtained from The Everglades, West Palm Beach, and Davie. After these soil samples were collected, they were serially diluted and plated to isolate bacteria. Isolated bacteria from the diluted plates were tested against tester strains to determine if a zone of inhibition was present. Isolates that presented of zone of inhibition were further characterized via Basic Local Alignment Search Tool (BLAST) Analysis to identify the genus of the bacteria. We have also identified …

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Love Another Day, Emalee Shrewsbury Apr 2016

Love Another Day, Emalee Shrewsbury

Undergraduate Student Symposium

“Love Another Day” is a short dramatic film about Tucker, who shuns love after a series of blind dates go wrong, all in an attempt to lead a life he feels is more suitable and happy. The film is directed by Emalee Shrewsbury. Other crew members and actors include Sandra Badrous, Kirin Kaur, Gabby McCue, Ashley Rivera, Shannon Alivio, and Joshua Haeffner.

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Measuring The Time Diffusion Of A Colored Gas In A Small Enclosed Container, Fernando Reachy-Guadarrama Apr 2016

Measuring The Time Diffusion Of A Colored Gas In A Small Enclosed Container, Fernando Reachy-Guadarrama

Undergraduate Student Symposium

The diffusion time measurement of colored gases in closed containers is extremely important for many experiments in chemistry. For example, we used the diffusion time (Δt) of iodine in air -inside a closed container- to calculate the free mean path (λ) of molecules by using the relation λ = (Srms)2/(≺υ≻δt); here ≺υ≻ is the average molecular speed of the gas and Srms can be reasonably estimate to be one-half of the predetermine height that the gas has to reach. The usual method to measure Δt for a vertically upward …

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Quantitative Measurement Of Learning And Memory In Caenorhabditis Elegans In Response To An Engineered Nematicidal Bacterium, Krunal Patel, Natalie Neves Apr 2016

Quantitative Measurement Of Learning And Memory In Caenorhabditis Elegans In Response To An Engineered Nematicidal Bacterium, Krunal Patel, Natalie Neves

Undergraduate Student Symposium

Despite their global prevalence, there are very few strategies to prevent infections due to parasitic nematodes. Recent studies have shown that bacteria engineered using the principles of synthetic biology may serve as an alternative approach to intoxicating nematodes. While these engineered bacteria were initially shown to be relatively efficacious in intoxicating the model nematode Caenorhabditis elegans, the nematodes quickly learned to avoid the engineered bacteria through aversive associative learning, rendering them less effective as biocontrols. In this study, we sought to quantify the rate at which C. elegans learns to avoid the engineered nematicidal bacteria. Using nematode learning assays, …

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Quick Contrast Sensitivity Function Testing In Adults Without Ocular Disease And Patients With Retinitis Pigmentosa, Manonmani Murugappan Apr 2016

Quick Contrast Sensitivity Function Testing In Adults Without Ocular Disease And Patients With Retinitis Pigmentosa, Manonmani Murugappan

Undergraduate Student Symposium

The objective was to determine the reliability and range of results for area under the log contrast sensitivity function (AULCSF) measures obtained with the quick contrast sensitivity function (qCSF) test in adults without eye disease and those with retinitis pigmentosa (RP). Nineteen RP patients and 39 adults with normal visual acuity (VA better than 20/25) and no ocular disease repeated qCSF testing at two sessions within ~1 week binocularly and monocularly, as well as with a NoIR 4% transmission filter to simulate low illumination in the eye with better VA for normals and binocularly for RP patients. Compared to younger …

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Recovery Of Larval Strongylid Nematodes From Raccoon, Procyon Lotor, Hema Narlapati, Rebekah St. Godard Apr 2016

Recovery Of Larval Strongylid Nematodes From Raccoon, Procyon Lotor, Hema Narlapati, Rebekah St. Godard

Undergraduate Student Symposium

A major challenge in the development of biocontrol methods targeting intestinal helminths is the lack of readily available strongylid experimental models that are also noninfective to humans. Noninfectivity to humans (and other nontarget organisms) is an important criterion for such models as this allows them to be used experimentally with minimal biosecurity measures, in standard laboratory settings. Preliminary laboratory work on raccoon feces in the context of an undergraduate parasitology course indicated that local raccoons are host to a specialist strongylid, Arthrocephalus lotoris, which only infects raccoons and skunks. Athrocephalus does not directly penetrate into its host, but must …

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The Impact Of Social Media On Small And Medium Businesses, Albert Baldoni Apr 2016

The Impact Of Social Media On Small And Medium Businesses, Albert Baldoni

Undergraduate Student Symposium

In the past few years, social media’s popularity has increased exponentially. Its fundamental uses were for entertainment, but as it evolved, it became a greater part of everyone’s lives; including businesses. This analysis takes a look at the impact of social media and networking on small and medium enterprises (SMEs). First the characteristics of businesses adopting social media will be analyzed to see what factors promote its adoption. These aspects are grouped into the three main categories of organizational, manager, and environmental. Then, the impact of social media adding value to a company through branding will be looked at. This …

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The Impact Of The Patient Protection And Affordable Care Act On Businesses And The American Workforce, Shona Joseph Apr 2016

The Impact Of The Patient Protection And Affordable Care Act On Businesses And The American Workforce, Shona Joseph

Undergraduate Student Symposium

The Patient Protection and Affordable Care Act or PPACA has caused many changes that have affected both businesses and employees. Many businesses have lost profits because they had to provide insurance for their workers. Thus, some businesses have changed their organization structures in order to combat mandates from the PPACA. First, businesses have cut down the number of employees working for their firm in order to have fewer than fifty workers. When a business is under fifty employees, it is considered a small business allowing it the right to legally not have to provide health insurance for its workers. Secondly, …

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The Linguistics Of Terrorism, Leigh-Ana Mumford Apr 2016

The Linguistics Of Terrorism, Leigh-Ana Mumford

Undergraduate Student Symposium

With the inequities present around the world, the nature of terrorism is both puzzling and ruinous. What remains irrefutable about terrorism is how its connotation translates into its accepted definition. Political rhetoric often utilizes “terrorism” to create a narrative, often to justify the use of state violence to preserve “national security.” This research investigates to what extent the definition of terrorism has been altered to serve as a mask for naked self-interest by the US state and political elites. Emphasis will be placed on spikes of anti-terrorism rhetoric in US foreign policy since the 1980’s. Three case studies display the …

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The Role Of Cheating Behavior And Personality Traits In Deception Detection Ability, Joshua Braverman Apr 2016

The Role Of Cheating Behavior And Personality Traits In Deception Detection Ability, Joshua Braverman

Undergraduate Student Symposium

In this study we examined the relationship that propensity for cheating, as well as several other personality traits, have with deception detection ability. Participants were first administered a behavioral measure of their tendency to cheat on a short mathematics exam, as well as a measure of anger toward hypothetical cheaters. Second, participants viewed a series of video clips of NSU students making truthful and deceptive statements; participants attempted to discriminate between truthful and deceptive statements, and also rated the personality traits of the NSU students. Third, participants attempted to discriminate between truthful and deceptive statements in 8 media clips of …

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Using Engineered Bacteria To Explore Biological Invasions, Josue Conde, Neil Thackar Apr 2016

Using Engineered Bacteria To Explore Biological Invasions, Josue Conde, Neil Thackar

Undergraduate Student Symposium

One critical ecological challenge is to circumvent invasion from non-indigenous organisms. Studying the factors that affect the ability of a non-indigenous species to colonize and spread into a new territory is very challenging due to multiple confounding factors. Synthetic biology is often not subject to these confounds, and thus we utilize it to explore factors that allow invasive species to successfully invade a new area. Specifically, we use engineered bacteria that are programmed to have an Allee effect, a fundamental growth dynamic that is observed in most invasive species. Using these bacteria, we take a two-pronged approach. First, we examine …

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Yoga - Beyond The Asana, Christa Barone Apr 2016

Yoga - Beyond The Asana, Christa Barone

Undergraduate Student Symposium

“Yoga - Beyond the Asana” is a documentary that explores the yoga lifestyle, demonstrating that yoga is for everyone. This documentary shatters preconceived notions, one yoga class at a time. The documentary is directed by Christa Barone.

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Defining Success: Developing An Effective Grassroots Mobilization Strategy, Nucleus Shelton Apr 2016

Defining Success: Developing An Effective Grassroots Mobilization Strategy, Nucleus Shelton

Undergraduate Student Symposium

The ability of citizens to petition elected officials for the purpose of redressing grievances are essential tenets to any functioning democracy. This research focuses on examining the divergent political outcomes of the Taxed Enough Already (TEA) Party and the Occupy Wall Street movement. The research seeks to understand why was one able to produce viable political candidates and gain considerable influence over the American political system, while the other withered away into the history of American politics. The researcher emphasizes different aspects of grassroots politics including framing, organizational structure, and resource mobilization. The research is conducted as a qualitative empirical …

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Development Of A Library Of Synthetic Compounds With Multiple Pharmacophores, Alissa Svedberg, Zachary Galloway, Akshay Naraine Apr 2016

Development Of A Library Of Synthetic Compounds With Multiple Pharmacophores, Alissa Svedberg, Zachary Galloway, Akshay Naraine

Undergraduate Student Symposium

It is known that chalcones and pyrazolines possess antibacterial and antifungal activity; the overall goal of this project was the development of a library by synthesizing novel hybrids containing both chalcones and pyrazolines. The hybrids may show antibacterial efficiency against S. aureus, E. coli, and Candida albicans. Oxindole derivatives have shown previous biological activity in combating bacteria such as S. aureus and E. coli, but using N-alkylation, the novel derivative may be further reacted using various aldehydes yielding a library of hybrids that may have antimalarial, antitubercular, and cytotoxic effects.

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Efficiency Of An Electrostatic Sprayer In The Application Of Disinfectant, Karan Patel, Leonor Sarria, Antonia Bukatevych Apr 2016

Efficiency Of An Electrostatic Sprayer In The Application Of Disinfectant, Karan Patel, Leonor Sarria, Antonia Bukatevych

Undergraduate Student Symposium

Continuing research and development has led to new advancements in sanitation technology which allows for better preventative techniques against disease and illnesses. A total solutions company, ByoPlanet, developed an electrostatic sprayer that applies a negative charge to a disinfectant. This permits a stronger attraction to the environment as objects are naturally positively charged. Our goal was to determine if the electrostatic sprayer was able to treat objects that are not in the direct line of contact with the spray. The treatment was Clorox Hydrogen Peroxide and water was used as a control. The electrostatic sprayer was placed three feet from …

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Evaluation Of The Cytotoxic Profile Of Metformin And Y15 In Platinum Resistance Ovarian Cancer Cells, Keerthi Thallapureddy, Sam Batko, Zara Khan Apr 2016

Evaluation Of The Cytotoxic Profile Of Metformin And Y15 In Platinum Resistance Ovarian Cancer Cells, Keerthi Thallapureddy, Sam Batko, Zara Khan

Undergraduate Student Symposium

Metformin, an antidiabetic drug, has been previously shown to induce cytotoxicity in platinum resistant ovarian cancer cells and increase phosphorylation of Focal Adhesion Kinase (FAK), a tyrosine kinase implicated in the development of this platinum resistance. Therefore, we evaluated the combined cytotoxic efficacy of Metformin and the focal adhesion kinase inhibitor 1,2,4,5-Benzene Tetra amine tetra hydrochloride (Y15) in platinum resistant OVCAR 3 ovarian cancer cells. The cells were treated with concentrations of Y15 and Metformin to determine IC50 values, which were then used to treat cells with Y15 and Metformin separately and in combination. DNA fragmentation and poly ADP …

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