Digital Commons Network^™

Mathematical Modeling And Simulation Of Human Motion Using 3-Dimensional, Multi-Segment Coupled Pendulum System : Derivation Of A Generalized Formula For Equations Of Motion, Loay Ahmed-Wasfe Al-Zube

Theses

The use of mathematical models to investigate the dynamics of human movement relies on two approaches: forward dynamics and inverse dynamics. In this investigation a new modeling approach called the Boundary Method is outlined. This method addresses some of the disadvantages of both the forward and the inverse approach. The method yields as output both a set of potential movement solutions to a given motor task and the net muscular impulses required to produce those movements. The input to the boundary method is a finite and adjustable number of critical target body configurations. In each phase of the motion that …

Systems Integration With Dlsi, Tarun Preet S. Bedi

Theses

Systems integration aims to provide a homogenous view to a system consisting of many heterogeneous systems. Systems integration can be achieved by many means out of which the middleware approach is the most popular. This is because middleware can be built around existing systems thereby reducing the amount of changes needed for the integration. Nowadays many middleware technologies are available to integrate heterogeneous systems. One can chose among them depending upon the requirements. But due to the many technologies available for Middleware, a muddle of middleware exists. To reduce this muddle and to integrate the systems already implemented using different …

Incineration And Environmental Justice : The Case Of Communities Around Connecticut Resource Recovery Facilities, Michael A. Bilheimer

Theses

The current depleting landfill capacity in Connecticut means that resource recovery facilities will be relied on heavily to meet the States' waste disposal needs. This heavy reliance on these facilities will place greater burdens on the host communities of these waste facilities. Therefore it is important to examine the citing of these facilities to determine if these sitings unfairly targeted a particular segment of the population.

To determine if siting has been unjust in Connecticut, this study uses a geographic information system (GIS) to analyze demographic data surrounding each facility in a comparison of demographic data from 1990 and 2000 …

The Rise And Fall Of Open Market Emissions Trading In New Jersey, Devin Peter Demarco

Theses

On August 2, 1996, the New Jersey Department of Environmental Protection (NJDEP) promulgated rules governing its Open Market Emissions Trading (OMET) program. With a goal to provide industry with a greater degree of flexibility in meeting federal air compliance directives and simultaneously move the state towards the attainment of National Ambient Air Quality Standards (NAAQS), this program is now slated for termination following scrutiny from the federal Environmental Protection Agency (EPA), environmental groups and a new NJDEP administration.

This thesis discusses the basis for this scrutiny and other program flaws discovered through interviews with, and public comments from, NJDEP and …

A Clustered Back-Bone For Routing In Ad-Hoc Networks, Delzad Kothawala

Theses

In the recent years, a lot of research work has been undertaken in the area of ad-hoc networks due to the increasing potential of putting them to commercial use in various types of mobile computing devices. Topology control in ad-hoc networks is a widely researched topic; with a number of algorithms being proposed for the construction of a power-efficient topology that optimizes the battery usage of the mobile nodes.

This research proposes a novel technique of partitioning the ad-hoc network into virtually-disjoint clusters. The ultimate aim of forming a routing graph over which power-efficient routing can be implemented in a …

Design And Implementation Of Heart Rate Variability Measures In The Time Domain, Binoy John Mathews

Theses

The following study was conducted to design and implement computer programs to derive five time domain and two frequency domain Heart Rate Variability (HRV) measures from 24 hour Holter monitor recordings and to generate activity plots that display the variation of three of the five time domain measures and two frequency domain measures over a period of 24 hours.

Working with known pre and post experimental ECG data taken from a cyclical exercise program, standard parameters in both the time and frequency domains were derived using programs designed in Labview 7.0 engineering software package. Five parameters in the time domain …

Review Of Algorithms For Rna Secondary Structure Prediction With Pseudoknots, Ingrid Helene Nielsen

Theses

Pseudoknots are structures that are formed from the base pairing of an RNA secondary loop structure with a complementary base which lies somewhere outside of the loop. The result is a structure, which plays a vital role in cell structure rigidity, regulation of protein synthesis, and in the structural organization of RNA complexes. Deciphering RNA folding patterns would begin to unravel some of the mysteries surrounding the cell and its functions and open a new world to scientists. Many algorithms have been written in this quest to predict RNA's secondary structure but not many have been very successful.

In this …

Extending The Boundary Method For Solving Human Motion Problems Using A 3 Dimensional Coupled Pendulum Model, Avani Janardan Patel

Theses

Mathematical modeling, an evolving area in movement analysis research, couples quantitative measures of human motion with theoretical concepts in physiology and mechanics. Literature reveals two methods to solve for human motion problems, Forward and Inverse Mechanics. In this investigation, a new approach called the Boundaty Method is adopted to solve for human motion. This approach has the advantage of being able to solve for both new motions and the net muscular joint forces required to produce those motions but only at those discrete times and body configurations that are believed to be most crucial for accomplishing the task.

The method …

Human Factors Approach Towards Improving Readability Of Bus Schedules, Anand Tharanathan

Theses

Due to an increasing concern over the readability of existing bus schedules of a public transportation agency the schedule format was redesigned. Two prototype schedules were designed based on the gathered information from the literature survey, focus group meetings and data from other public transportation agencies' schedules. One of the prototypes was designed by giving primary importance to the direction of travel and was named the directional prototype schedule. The other prototype was designed by giving primary importance to the day of the week, and was named weekday / weekend prototype schedule. A time based laboratory experiment and a subjective …

Mathematical Modeling Of Transient State Transdermal Drug Delivery, Alison Nickol Weltner

Theses

In this work, a two-pathway mathematical model for transdermal drug delivery with iontophoresis is presented. The partial differential equations are described and then solved. An alternative, two-pathway, three-layer model is also presented, and the implications of the coefficients within the equation are discussed. Using Franz cell iontophoretic delivery data from three drug substances (amitriptyline HCl, clomipramine HCl, and nortriptyline HCl), the two-pathway model is regressed to determine the diffusion coefficient and the concentration within the skin at the drug reservoir interface. ANOVA analysis indicates a correlation between iontophoretic current and concentration of drug within the stratum corneum.

Analysis Of Molecular Conformations Using Relative Planes, Deepa S. Pai

Theses

Ring substructures of a drug usually participate actively in binding to the receptor. It is necessary to study the spatial relationship of these molecular recognition features in order to determine the pharmacophore of the drug. This is a particularly difficult problem when the drug is a flexible molecule with many energetically accessible conformations.

In this research an innovative approach to calculate the relative displacement and orientation of every possible pair of rings in a given molecule was designed, tested, and implemented in the "Planes" program. Planes were defined from each of the ring substructures and the displacement and rotation of …

Random Search Conformational Analysis Of Piperazine And Piperadine Analogs Of Gbr12909 : Implicit Aqueous Solvation Effects, William A. Roosma

Theses

The object of this work was to study the effect of solvent on the conformational potential energy surface (PES) of GBR12909 analogs. Local minima on the PES's were found by the Random Search algorithm using the Sybyl molecular modeling package from Tripos, Inc., and an implicit solvent model. Two force-field/charge models were employed in the analysis: the Tripos force field with Gasteiger-Huckel charges and the MMFF94 force field with MMFF94 charges.

The effect of solvent on the location of minima in multi-dimensional torsional angle space was studied by comparison to the vacuum phase results. Minima were plotted in torsional angle …

Effects Of Sleep Deprivation On Autonomic Nervous System, Jaeyeaon Cho

Theses

Sleep deprivation (SD) has been thought a potential factor to trigger cardiovascular events by increasing the sympathetic nervous system activity. The aim of the present study was to evaluate the relationship between sleep deprivation and the autonomic nervous system activity by means of heart rate variability (HRV) and blood pressure variability (BPV). All data were acquired in the sleep lab of Columbia University.

Data were acquired from the two groups, SD and control. Subjects in the SD group did not sleep for thirty-six hours but subjects in the control group slept at night as usual. There were five different data …

Participatory Learning Environment : Requirements And Design Analysis, Vikas Manohar Achhpiliya

Theses

The primary purpose of this thesis is to develop the requirements and model preliminary database and class designs for the Participatory Learning Approach Environment (PLAE). The requirements and the designs will be presented for version 1.0 and 2.0 with version 2.0 supporting an enhanced requirements set.

Participatory Learning Approach Environment (PLAE) is an exercise management tool for the Participatory Learning Approach (PLA) - a pedagogy approach based on the theory of constructivism. The PLAE facilitates and enhances learning among students while easing the administrative burden of the instructor and cognitive overload of the students. The theory and concepts on which …

Supply Chain Risk Mitigation, Roshan R. Pai

Theses

In recent years, especially post 9/11, there has been an increasing awareness for securing business supply chains against probable disruptions. With globalization and lean inventories, the efficiency of supply chain has greatly enhanced over the years, but at the expense of new vulnerabilities. Supply chain vulnerabilities have resulted in disruptions to the economic stability and security. As a result, risk analysis and mitigation has now grown to become one of the key links to business stabilization. To ensure business continuity, it is necessary to identify key assets (physical and operational) within the supply chain and secure them against probable threats. …

Electronic Marketplaces And Their Roles In The Staffing Industry : An Explorative Analysis, Vishal Khubani

Theses

This thesis will explore and analyze the role of electronic marketplaces in the staffing industry from the viewpoint of hiring executives, human resources personnel, staffing organizations, and candidates. Using analyses of popular electronic job marketplaces, this paper will establish the efficiency and effectiveness of electronic marketplaces as compared to traditional staffing methods. It will also provide a detailed view of various electronic marketplaces, their financial structure and analysis of their performance. This information will also result in a return on investment estimate for the average hiring organization using electronic marketplaces.

Simulation Analysis Of Anti-Rollover Mechanism For Vehicles, Mohib L. Raid

Theses

Rollover accidents are considered the most significant safety problems for all classes of light vehicles, especially pickups, Sport Utility Vehicles (SUV), Light Truck Vehicle (LTV) and vans. The main objective of the research is the design of a new mechanism able to keep the vehicle stable under various road conditions and high speeds, to prevent the vehicle from rolling over and to maintain the stability for the vehicle by creating an anti-rolling torque on the vehicle body capable of turning the vehicle smoothly to stable position.

Analysis Of Auf1 Targeted Mrna Sequences, Jiebo Lu

Theses

AUF 1, an A+U rich element (ARE) binding protein, plays an important role in mRNA decay. To identify the mRNAs that interact with AUF 1, mRNA derived from a human cardiac cDNA expression library was purified by AUF 1 affinity chromatography and cloned following RT-PCR. 261 sequences were obtained. The sequences were searched against two protein databases and four nucleic acid databases, and the sequence information and database search results were input into a local Microsoft Access database, BLAST-AUF 1, by Java applets for parsing document. Analysis of protein information by querying BLAST-AUF 1 identified 194 function-known proteins, which were …

Fabrication Of Nanofiber Scaffolds By Electrospinning And It's Potential For Tissue Engineering, Shobana Shanmugasundaram

Theses

Electrospinning is a fabrication process that uses an electric field to control the deposition of polymer fibers on to a target substrate. This electrospinning strategy can be used to fabricate fibrous polymer mats composed of fiber diameters ranging from several microns down to tens of nanometers. This study assesses the potential of electrospinning, as an alternative scaffold fabrication technique for tissue engineering applications. In this study, electrospinning is adapted to produce tissue-engineering scaffolds of two different size ranges composed of non-woven poly-L-lactide (PLLA) nanofibers and as a first study, the potential use of these scaffolds as tissue engineering scaffolds was …

Adaptive Learning For Event Modeling And Pattern Classification, Shuangshuang Dai

Dissertations

It is crucial to detect, characterize and model events of interest in a new propulsion system. As technology advances, the amount of data being generated increases significantly with respect to time. This increase substantially strains our ability to interpret the data at an equivalent rate. It demands efficient methodologies and algorithms in the development of automated event modeling and pattern recognition to detect and characterize events of interest and correlate them to the system performance. The fact that the information required to properly evaluate system performance and health is seldom known in advance further exacerbates this issue.

Event modeling and …

Virtual Teams Combining Mobile Devices With Web-Based Communication On Group Decision Making, Hyo-Joo Han

Dissertations

Organizations have moved from a face-to-face team environment to a virtual team environment using communication technology during the last decade. More and more workers use asynchronous tools (including email, discussion groups, information sharing tools, and group calendaring systems), and synchronous tools, such as instant messaging and web-based chatting features, to coordinate and share information with people within and outside of organizations. This empirical study on how virtual teams work, integrating mobile devices with web-based group communication for decision-making tasks, examines which technologies and communication modes are the best for distributed group teamwork, and, mainly, what are the predictive characteristics making …

Intercity Travel Demand : A Utility-Consistent Simultaneous Trip Generation And Mode Choice Model, Guilin Li

Dissertations

An intercity travel decision includes a complex set of subdecisions, such as when to travel, where to travel, which mode to choose, and others. The main focus of this dissertation is to examine trip frequency and mode choice of intercity non-business travel.

The objective of this study is to understand intercity travel behavior using disaggregate models. The proposed conceptual framework for intercity travel behavior leads to a nested logit/continuous choice model that is rigorously linked to the utility maximization theory. Compared to a traditional intercity travel demand model, the proposed model is utility consistent in that trip generation and mode …

Effect Of Fullerene Containing Lubricants On Wear Resistance Of Machine Components In Boundary Lubrication, Andriy Titov

Dissertations

Fullerenes, a new form of carbon nanomaterials, possess unique physical and mechanical properties that make their use as additives to liquid lubricants potentially beneficial. The goal of this study was to investigate the effect of fullerene containing lubricants on wear resistance of steel-bronze couples operating under boundary lubrication conditions. A mathematical model of deformed asperity contact was built to calculate real contact area and real contact pressure. Computer controlled wear friction testing methodology and equipment were designed, developed and implemented for obtaining reliable and objective experimental data. In addition, optical and scanning electron microscopy and standard surface texture analysis were …

Migration Of An Intruder Particle In A Boundary Driven Shear Flow, Jian Liu

Dissertations

This study reports on three-dimensional, discrete element simulations of a single large spherical intruder in a Couette shear flow composed of uniform sized particles. The simulation results are useful in providing a numerical reproduction of the experiments for size segregation and mixing. This in turn has a major importance in many industries which are concerned with handling of particles and powders, such as pharmaceutical manufacturing, agriculture, chemical and mineral processing.

Discrete element simulations are carried out using the "soft sphere" model of Walton, et. al., which provides a method for obtaining the information at a macroscopic level from multi-body collisions …

Studies On Improved Integrated Membrane-Based Chromatographic Process For Bioseparation, Yanke Xu

Dissertations

To improve protein separation and purification directly from a fermentation broth, a novel membrane filtration-cum-chromatography device configuration having a relatively impermeable coated zone near the hollow fiber module outlet has been developed. The integrated membrane filtration-cum-chromatography unit packed with chromatographic beads on the shell side of the hollow fiber unit enjoys the advantages of both membrane filtration and chromatography; it allows one to load the chromatographic media directly from the fermentation broth or lysate and separate the adsorbed proteins through the subsequent elution step in a cyclic process.

Interfacial polymerization was carried out to coat the bottom section of the …

The Use Of A Water Quality Model To Evaluate The Impacts Of Combined Sewer Overflows On The Lower Hudson River, Wen-Pin Shu

Dissertations

CSO discharges have long been recognized as a significant source of water pollution. While many sources of water pollution have been controlled over the past 20 years, CSOs continue to be a main environmental concern in several areas, especially in old cities. In the past, most CSO research focused on the CSO control processes, including floatables and suspended solids removal. Few studies have been conducted in the area of the impacts of CSO discharge on the receiving water quality. To achieve this purpose, a powerful water-modeling tool, WASP 6.1, is utilized in this study. The Lower Hudson River is selected …

Vibration-Induced Densification Of Granule Materials, Ninghua Zhang

Dissertations

Physical experiments as well as discrete element simulations of vibration are carried out. The use of different amplitudes and frequencies are applied in the experiments to facilitate the observation of densification trends with mono-disperse acrylic spheres and multi-disperse polyethylene pellets. For mono-disperse acrylic spheres, four densification trends are found at different vibration conditions, and attaining the "maximum density" is closely related to the combination of vibration frequency and amplitude, in agreement with experiments in the literature. For multi-disperse polyethylene pellets, there is a substantial increase in solids fraction due to the effects of particle shape and surface friction. Computer simulations …

Multi-Spectral Light Interaction Modeling And Imaging Of Skin Lesions, Sachin Vidyanand Patwardhan

Dissertations

Nevoscope as a diagnostic tool for melanoma was evaluated using a white light source with promising results. Information about the lesion depth and its structure will further improve the sensitivity and specificity of melanoma diagnosis. Wavelength-dependent variable penetration power of monochromatic light in the trans-illumination imaging using the Nevoscope can be used to obtain this information. Optimal selection of wavelengths for multi-spectral imaging requires light-tissue interaction modeling. For this, three-dimensional wavelength dependent voxel-based models of skin lesions with different depths are proposed. A Monte Carlo simulation algorithm (MCSVL) is developed in MATLAB and the tissue models are simulated using the …

Ip-Based Virtual Private Networks And Proportional Quality Of Service Differentiation, Jingdi Zeng

Dissertations

IP-based virtual private networks (VPNs) have the potential of delivering cost-effective, secure, and private network-like services. Having surveyed current enabling techniques, an overall picture of IP VPN implementations is presented.

In order to provision the equivalent quality of service (QoS) of legacy connection-oriented layer 2 VPNs (e.g., Frame Relay and ATM), IP VPNs have to overcome the intrinsically best effort characteristics of the Internet. Subsequently, a hierarchical QoS guarantee framework for IP VPNs is proposed, stitching together development progresses from recent research and engineering work.

To differentiate IP VPN QoS, the proportional QoS differentiation model, whose QoS specification granularity compromises …

High Resolution Solar Observations In The Context Of Space Weather Prediction, Guo Yang

Dissertations

Space weather has a great impact on the Earth and human life. It is important to study and monitor active regions on the solar surface and ultimately to predict space weather based on the Sun's activity. In this study, a system that uses the full power of speckle masking imaging by parallel processing to obtain high-spatial resolution images of the solar surface in near real-time has been developed and built. The application of this system greatly improves the ability to monitor the evolution of solar active regions and to predict the adverse effects of space weather. The data obtained by …