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Mutations In The Pectin Methyltransferase Quasimodo2 Influence Cellulose Biosynthesis And Wall Integrity In Arabidopsis, Juan Du, Alex Kirui, Shixin Huang, Lianglei Wang, William J. Barnes, Sarah N. Kiemle, Yunzhen Zheng, Yue Rui, Mei Ruan, Shiqian Qi, Seong H. Kim, Tuo Wang, Daniel J. Cosgrove, Charles T. Anderson, Chaowen Xiao Nov 2020

Mutations In The Pectin Methyltransferase Quasimodo2 Influence Cellulose Biosynthesis And Wall Integrity In Arabidopsis, Juan Du, Alex Kirui, Shixin Huang, Lianglei Wang, William J. Barnes, Sarah N. Kiemle, Yunzhen Zheng, Yue Rui, Mei Ruan, Shiqian Qi, Seong H. Kim, Tuo Wang, Daniel J. Cosgrove, Charles T. Anderson, Chaowen Xiao

Faculty Publications

© 2020 ASPB. Pectins are abundant in the cell walls of dicotyledonous plants, but how they interact with other wall polymers and influence wall integrity and cell growth has remained mysterious. Here, we verified that QUASIMODO2 (QUA2) is a pectin methyltransferase and determined that QUA2 is required for normal pectin biosynthesis. To gain further insight into how pectin affects wall assembly and integrity maintenance, we investigated cellulose biosynthesis, cellulose organization, cortical microtubules, and wall integrity signaling in two mutant alleles of Arabidopsis (Arabidopsis thaliana) QUA2, qua2 and tsd2. In both mutants, crystalline cellulose content is reduced, cellulose synthase particles move …

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A Theory Of Multiformat Communication: Mechanisms, Dynamics, And Strategies, Jordan W. Moffett, Judith Anne Garretson Folse, Robert W. Palmatier Nov 2020

A Theory Of Multiformat Communication: Mechanisms, Dynamics, And Strategies, Jordan W. Moffett, Judith Anne Garretson Folse, Robert W. Palmatier

Faculty Publications

Extant communication theories predate the explosion of digital formats and technological advances such as virtual reality, which likely explains their predominant focus on traditional and format-level (e.g., face-to-face, email) rather than digital or characteristic-level (e.g., visual cues, synchronicity) design decisions. Firms thus lack insights into how to create and use emerging digital formats, individually or synergistically. To establish a holistic framework of bilateral multiformat communication for relationship marketing, this article reviews communication theory to establish a foundation for understanding multiformat communication and to identify any gaps (e.g., AI agents, simulated cues). The authors then review bilateral communication research in light …

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A Coded Aperture Microscope For X-Ray Fluorescence Full-Field Imaging, D. P. Siddons, A. J. Kuczewski, A. K. Rumaiz, R. Tappero, M Idir, K. Nakhoda, J. Khanfri, V. Singh, E. R. Farquhar, M. Sullivan, D. Abel, D. J. Brady, X. Yuan Nov 2020

A Coded Aperture Microscope For X-Ray Fluorescence Full-Field Imaging, D. P. Siddons, A. J. Kuczewski, A. K. Rumaiz, R. Tappero, M Idir, K. Nakhoda, J. Khanfri, V. Singh, E. R. Farquhar, M. Sullivan, D. Abel, D. J. Brady, X. Yuan

Faculty Publications

The design and construction of an instrument for full-field imaging of the X-ray fluorescence emitted by a fully illuminated sample are presented. The aim is to produce an X-ray microscope with a few micrometers spatial resolution, which does not need to scan the sample. Since the fluorescence from a spatially inhomogeneous sample may contain many fluorescence lines, the optic which will provide the magnification of the emissions must be achromatic, i.e. its optical properties must be energy-independent. The only optics which fulfill this requirement in the X-ray regime are mirrors and pinholes. The throughput of a simple pinhole is very …

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A Solution For Funding The Development Of Technology In Oilwell Drilling, Dalmo S. Amorim, Otto L. A. Santos, Ricardo C. Azevedo, Ana Carolina Chieregati Nov 2020

A Solution For Funding The Development Of Technology In Oilwell Drilling, Dalmo S. Amorim, Otto L. A. Santos, Ricardo C. Azevedo, Ana Carolina Chieregati

Faculty Publications

This article proposes a novel methodology to solve an existing gap in benchmark definition by the adoption of statistically defined benchmarks as references to test products or technical procedures. In a win-win partnership, remuneration is made upon realistic bases of comparison being proportional to existing risks. However, establishing values for benchmarks is rarely unanimous if asked to different persons involved in drilling analysis. Conventional benchmarking, which enhances few results and leaves aside poor operational performances, produces references that do not properly represent the geological environment. Nonetheless, when testing new products, it serves as reference to remunerate suppliers. The review of …

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Single-Case Experimental Designs For Behavioral Neuroscience, Paul L. Soto Nov 2020

Single-Case Experimental Designs For Behavioral Neuroscience, Paul L. Soto

Faculty Publications

Single-case experimental designs (SCEDs) are commonly used in behavior analytic research but rarely used in behavioral neuroscience research. The recent development of technologies that allow control of the timing of neurobiological events such as gene expression and neuronal firing enable the fruitful application of SCEDs for the study of brain-behavior relations. There are at least 3 benefits expected from applying SCEDs to study how neurobiological events affect behavior. First, SCEDs entail direct within- and across-subject assessments of reliability, likely increasing the probability of replication across studies and encouraging a search for the causes of replication failure when they occur. Second, …

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Psychometric Analyses Of The Eating And Food Literacy Behaviors Questionnaire With University Students, Kwadernica C. Rhea, Melissa W. Cater, Kevin Mccarter, Georgianna Tuuri Nov 2020

Psychometric Analyses Of The Eating And Food Literacy Behaviors Questionnaire With University Students, Kwadernica C. Rhea, Melissa W. Cater, Kevin Mccarter, Georgianna Tuuri

Faculty Publications

Objectives: This study developed and validated a questionnaire to measure young adults’ perceived food literacy and behaviors toward food and created an explanatory model. Design: Cross-sectional. Setting: Large southeastern US university. Participants: A total of 1,896 students, aged 18–30 years, were recruited. Data from 1,813 were analyzed. Variables Measured: Health and nutrition, taste, food preparation, planning and decision-making, and convenience. Analysis: Exploratory factor analysis, test-retest reliability, confirmatory factor analysis, and structural equation modeling were performed. Results: Exploratory factor analysis returned 5 factors with acceptable internal structure. Test-retest reliability coefficients ranged from 0.63 to 0.92. Confirmatory factor analysis suggested that a …

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Utilization Of Deep Learning For Subphenotype Identification In Sepsis-Associated Acute Kidney Injury, Kumardeep Chaudhary, Akhil Vaid, Áine Duffy, Ishan Paranjpe, Suraj Jaladanki, Manish Paranjpe, Kipp Johnson, Avantee Gokhale, Pattharawin Pattharanitima, Kinsuk Chauhan, Ross O’Hagan, Tielman Van Vleck, Steven G. Coca, Richard Cooper, Benjamin Glicksberg, Erwin P. Bottinger, Lili Chan, Girish N. Nadkarni Nov 2020

Utilization Of Deep Learning For Subphenotype Identification In Sepsis-Associated Acute Kidney Injury, Kumardeep Chaudhary, Akhil Vaid, Áine Duffy, Ishan Paranjpe, Suraj Jaladanki, Manish Paranjpe, Kipp Johnson, Avantee Gokhale, Pattharawin Pattharanitima, Kinsuk Chauhan, Ross O’Hagan, Tielman Van Vleck, Steven G. Coca, Richard Cooper, Benjamin Glicksberg, Erwin P. Bottinger, Lili Chan, Girish N. Nadkarni

Faculty Publications

Background and objectives Sepsis-associated AKI is a heterogeneous clinical entity. We aimed to agnostically identify sepsis-associated AKI subphenotypes using deep learning on routinely collected data in electronic health records. Design, setting, participants, & measurements We used the Medical Information Mart for Intensive Care III database, which consists of electronic health record data from intensive care units in a tertiary care hospital in the United States. We included patients ≥18 years with sepsis who developed AKI within 48 hours of intensive care unit admission. We then used deep learning to utilize all available vital signs, laboratory measurements, and comorbidities to identify …

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The Impact Of Information-Based Interventions On Conservation Behavior: A Meta-Analysis, Mehdi Nemati, Jerrod Penn Nov 2020

The Impact Of Information-Based Interventions On Conservation Behavior: A Meta-Analysis, Mehdi Nemati, Jerrod Penn

Faculty Publications

Interest in using information-based interventions to induce energy and water conservation has increased in recent years but have shown mixed evidence of their effectiveness. This paper seeks to answer two main questions - whether these programs are broadly effective in inducing conservation, and what are the most effective versions of these programs. Using a meta-analysis of 116 studies, we examine the effects of information-based interventions on residential customers' consumption of electricity, gas, and water. We find evidence of publication bias in this literature. After correcting for publication bias, meta-analysis results indicate that information-based interventions reduce consumption by an average of …

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Effects Of Cold Storage On Life-History Traits Of Aphidius Matricariae, Mehran Rezaei, Ali A. Talebi, Yaghoub Fathipour, Javad Karimzadeh, Mohammad Mehrabadi, Gadi V.P. Reddy Nov 2020

Effects Of Cold Storage On Life-History Traits Of Aphidius Matricariae, Mehran Rezaei, Ali A. Talebi, Yaghoub Fathipour, Javad Karimzadeh, Mohammad Mehrabadi, Gadi V.P. Reddy

Faculty Publications

Aphidius matricariae Haliday (Hymenoptera: Braconidae) is a polyphagous solitary endoparasitoid, attacking more than 40 species of aphids. This parasitoid is an important commercial product of many companies that produce biological control agents. Storage at low temperature increases the shelf life of many biocontrol agents, allowing companies to provide a steady and sufficient supply of insects for biocontrol programs. In the current study, the effects of cold storage of 1-day-old host mummies with A. matricariae for various time periods (5, 10, 15, 20, and 30 days) at 5 °C on the parasitoid’s key life-history traits were investigated. Parameters assessed after storage …

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Potential Link Between Compromised Air Quality And Transmission Of The Novel Corona Virus (Sars-Cov-2) In Affected Areas, M. G. Manoj, M. K. Satheesh Kumar, K. T. Valsaraj, C. Sivan, Soumya K. Vijayan Nov 2020

Potential Link Between Compromised Air Quality And Transmission Of The Novel Corona Virus (Sars-Cov-2) In Affected Areas, M. G. Manoj, M. K. Satheesh Kumar, K. T. Valsaraj, C. Sivan, Soumya K. Vijayan

Faculty Publications

The emergence of a novel human corona virus disease (COVID-19) has been declared as a pandemic by the World Health Organization. One of the mechanisms of airborne transmission of the severe acute respiratory syndrome corona virus (SARS-CoV-2) amid humans is through direct ejection of droplets via sneezing, coughing and vocalizing. Nevertheless, there are ample evidences of the persistence of infectious viruses on inanimate surfaces for several hours to a few days. Through a critical review of the current literature and a preliminary analysis of the link between SARS-CoV-2 transmission and air pollution in the affected regions, we offer a perspective …

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Discrete Bethe-Sommerfeld Conjecture For Triangular, Square, And Hexagonal Lattices, Jake Fillman, Rui Han Nov 2020

Discrete Bethe-Sommerfeld Conjecture For Triangular, Square, And Hexagonal Lattices, Jake Fillman, Rui Han

Faculty Publications

We prove the discrete Bethe-Sommerfeld conjecture on the graphene lattice, on its dual lattice (the triangular lattice), and on the extended Harper lattice. For each of these lattice geometries, we analyze the behavior of small periodic potentials. In particular, we provide sharp bounds on the number of gaps that may perturbatively open, we describe sharp arithmetic criteria on the periods that ensure that no gaps open, and we characterize those energies at which gaps may open in the perturbative regime. In all three cases, we provide examples that open the maximal number of gaps and estimate the scaling behavior of …

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Evaluation Of Asphalt Mixtures’ Resistance To Cement-Treated Base (Ctb) Reflective Cracking In The Laboratory, Husam Sadek, Marwa Hassan, Charles Berryman, Mohammad Hossain, Ipshit Idris Nov 2020

Evaluation Of Asphalt Mixtures’ Resistance To Cement-Treated Base (Ctb) Reflective Cracking In The Laboratory, Husam Sadek, Marwa Hassan, Charles Berryman, Mohammad Hossain, Ipshit Idris

Data

The primary objective of this project is to propose a laboratory setup to test and evaluate an asphalt mixture layer on top of a simulated Cement-Treated Base (CTB) layer against reflective cracking. An in-depth literature review on the experimental studies that were conducted throughout the world to investigate the resistance of asphalt mixtures to reflective cracking was conducted. Texas Transportation Institute (TTI) Overlay Tester (OT) was found to be the most appropriate equipment to study thermally-induced reflective cracking in the laboratory, and thereby was selected to be modified and used to assess the performance of asphalt mixtures on top of …

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Evaluation Of Bagasse Ash As Cement And Sand Replacement For The Production Of Engineered Cementitious Composites (Ecc), Gabriel Arce, Marwa Hassan, Sujata Subedi, Ana Rivas, Samantha Hidalgo, Hugo Eguez Nov 2020

Evaluation Of Bagasse Ash As Cement And Sand Replacement For The Production Of Engineered Cementitious Composites (Ecc), Gabriel Arce, Marwa Hassan, Sujata Subedi, Ana Rivas, Samantha Hidalgo, Hugo Eguez

Data

The objective of this study was to develop novel Engineered Cementitious Composites (ECC) materials implementing sugarcane bagasse ash (SCBA). To this end, the effects on the mechanical and physical properties of ECC materials of: (1) Louisiana raw SCBA (RBA) as a partial and complete replacement of sand (i.e., class S mixtures); (2) Louisiana post-processed SCBA (PBA) as a partial replacement of cement (i.e., class C mixtures); and (3) Ecuador raw SCBA (EBA) as a partial and complete replacement of sand (i.e., class S-E mixtures) were studied. Sand replacement levels with RBA and EBA evaluated were 25, 50, 75, and 100% …

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Rails To Resilience: Evaluating New Orleans And Baton Rouge Rail Terminals And Transit Links, Tara M. Tolford, James Amdal, Guang Tian, Alahna Moore, Marin Tockman Nov 2020

Rails To Resilience: Evaluating New Orleans And Baton Rouge Rail Terminals And Transit Links, Tara M. Tolford, James Amdal, Guang Tian, Alahna Moore, Marin Tockman

Publications

This study evaluates the multimodal linkages to and opportunities for proposed terminal sites for a potential future passenger rail connection between Baton Rouge and New Orleans, Louisiana. The project included a comprehensive analysis of recent planning processes and documents and distribution of a statewide survey aimed at understanding ridership potential (including non-work trips) and the needs of likely users, the results of which were modeled to illuminate key considerations for service design and station area planning. This study finds a strong foundation for, and support of, the proposed rail service, but distinct deficiencies in the current multimodal transportation environment connecting …

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Rails To Resilience: Evaluating New Orleans And Baton Rouge Rail Terminals And Transit Links, Tara M. Tolford, James Amdal, Guang Tian, Alahna Moore, Marin Tockman Nov 2020

Rails To Resilience: Evaluating New Orleans And Baton Rouge Rail Terminals And Transit Links, Tara M. Tolford, James Amdal, Guang Tian, Alahna Moore, Marin Tockman

Data

This study evaluates the multimodal linkages to and opportunities for proposed terminal sites for a potential future passenger rail connection between Baton Rouge and New Orleans, Louisiana. The project included a comprehensive analysis of recent planning processes and documents and distribution of a statewide survey aimed at understanding ridership potential (including non-work trips) and the needs of likely users, the results of which were modeled to illuminate key considerations for service design and station area planning. This study finds a strong foundation for, and support of, the proposed rail service, but distinct deficiencies in the current multimodal transportation environment connecting …

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Engineered Geopolymer Composites (Egcs) For Sustainable Transportation Infrastructure, Gabriel Arce, Marwa Hassan, Miladin Radovic, Svetlana Sukhishvili, Ruwa Abufarsakh, Oscar Huang, Sang Zhen, Mauricio Cornejo, Haci Baykara Nov 2020

Engineered Geopolymer Composites (Egcs) For Sustainable Transportation Infrastructure, Gabriel Arce, Marwa Hassan, Miladin Radovic, Svetlana Sukhishvili, Ruwa Abufarsakh, Oscar Huang, Sang Zhen, Mauricio Cornejo, Haci Baykara

Publications

The objective of this study was to develop novel Engineered Geopolymer Composite (EGC) materials implementing locally available ingredients to produce practical and cost-effective EGCs for repair and new construction of transportation infrastructure in the region. To this end, geopolymers (GPs) were synthesized by alkali activation of metakaolin (MK) or a combination of metakaolin and fly ash (MKFA) as GP precursors. MK-GPs were activated using sodium silicate and potassium silicate solutions prepared by dissolving silica fume (SiO2) and KOH or NaOH in deionized water. MKFA-GPs replaced silica fume using fly ash and were activated using only KOH solution. GP …

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Engineered Geopolymer Composites (Egcs) For Sustainable Transportation Infrastructure, Gabriel Arce, Marwa Hassan, Svetlana Sukhishvili, Ruwa Abufarsakh, Oscar Huang, Sang Zhen, Mauricio Cornejo, Haci Baykara Nov 2020

Engineered Geopolymer Composites (Egcs) For Sustainable Transportation Infrastructure, Gabriel Arce, Marwa Hassan, Svetlana Sukhishvili, Ruwa Abufarsakh, Oscar Huang, Sang Zhen, Mauricio Cornejo, Haci Baykara

Data

The objective of this study was to develop novel Engineered Geopolymer Composite (EGC) materials implementing locally available ingredients to produce practical and cost-effective EGCs for repair and new construction of transportation infrastructure in the region. To this end, geopolymers (GPs) were synthesized by alkali activation of metakaolin (MK) or a combination of metakaolin and fly ash (MKFA) as GP precursors. MK-GPs were activated using sodium silicate and potassium silicate solutions prepared by dissolving silica fume (SiO2) and KOH or NaOH in deionized water. MKFA-GPs replaced silica fume using fly ash and were activated using only KOH solution. GP …

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Evaluation Of Asphalt Mixtures’ Resistance To Cement-Treated Base (Ctb) Reflective Cracking In The Laboratory, Husam Sadek, Marwa Hassan, Charles Berryman, Mohammad Hossain, Ipshit Idris Nov 2020

Evaluation Of Asphalt Mixtures’ Resistance To Cement-Treated Base (Ctb) Reflective Cracking In The Laboratory, Husam Sadek, Marwa Hassan, Charles Berryman, Mohammad Hossain, Ipshit Idris

Publications

The primary objective of this project is to propose a laboratory setup to test and evaluate an asphalt mixture layer on top of a simulated Cement-Treated Base (CTB) layer against reflective cracking. An in-depth literature review on the experimental studies that were conducted throughout the world to investigate the resistance of asphalt mixtures to reflective cracking was conducted. Texas Transportation Institute (TTI) Overlay Tester (OT) was found to be the most appropriate equipment to study thermally-induced reflective cracking in the laboratory, and thereby was selected to be modified and used to assess the performance of asphalt mixtures on top of …

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Corrosion Management System Of Regional Reinforced Concrete (Rc) Bridges, Homero Castaneda, Ayman Okeil Nov 2020

Corrosion Management System Of Regional Reinforced Concrete (Rc) Bridges, Homero Castaneda, Ayman Okeil

Data

Civil infrastructure assets, including buildings, transportation networks, energy grids and networks, and water-sewer systems, are critical functional components of day-to-day life activity in a modern society. The durability and reliability of these civil infrastructures are largely affected by corrosion-induced structural deterioration. In addition to continual use and increasing traffic demands, natural environmental conditions set degradation due to corrosion damage as a critical condition to durable and reliable infrastructures. Therefore, in order to improve the durability of the bridge infrastructures affected by corrosion in the most efficient manor, we propose a procedure/methodology to manage integrity of corroding RC bridges which is …

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Extensions Of Real Bounded Symmetric Domains, Gestur Ólafsson, Robert J. Stanton Nov 2020

Extensions Of Real Bounded Symmetric Domains, Gestur Ólafsson, Robert J. Stanton

Faculty Publications

For a real bounded symmetric domain, G/K, we construct various natural enlargements to which several aspects of harmonic analysis on G/K and G have extensions. Our starting point is the realization of G/K as a totally real submanifold in a bounded domain Gh/Kh. We describe the boundary orbits and relate them to the boundary orbits of Gh/Kh. We relate the crown and the split-holomorphic crown of G/K to the crown Ξh of Gh/Kh. We identify an extension of a representation of K to a larger group Lc and use that to extend sections of vector bundles over the Borel compactification …

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P1 Finite Element Methods For An Elliptic State-Constrained Distributed Optimal Control Problem With Neumann Boundary Conditions, S. C. Brenner, M. Oh, L. Y. Sung Nov 2020

P1 Finite Element Methods For An Elliptic State-Constrained Distributed Optimal Control Problem With Neumann Boundary Conditions, S. C. Brenner, M. Oh, L. Y. Sung

Faculty Publications

We investigate two P finite element methods for an elliptic state-constrained distributed optimal control problem with Neumann boundary conditions on general polygonal domains. 1

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Enhancing The Performance Of Asphalt Mixtures Containing High Rap Content With The Use Of Different Wma Technologies, Husam Sadek, Marwa Hassan, Charles Berryman, Mohammad Hossain, Farah Zaremotekhases Nov 2020

Enhancing The Performance Of Asphalt Mixtures Containing High Rap Content With The Use Of Different Wma Technologies, Husam Sadek, Marwa Hassan, Charles Berryman, Mohammad Hossain, Farah Zaremotekhases

Data

The production of Warm-mix asphalt mixtures in conjunction with reclaimed asphalt pavement (RAP) has received considerable interest in recent years for economic and environmental reasons. The primary objective of this project is to enhance the performance of asphalt mixtures containing RAP in Region 6 using different WMA technologies. In this project, the effect of utilizing 0%, 25%, and 35% RAP contents on the performance of different WMA mixtures against rutting, moisture damage, and fatigue cracking are evaluated. The effects of the WMA technologies on the rutting performance of the asphalt mixtures and recovered binders were investigated using loaded wheel tracker …

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Bridge Deck Inspection Using Small Unmanned Aircraft Systems Based Airborne Imaging Techniques, Su Zhang, Shirley Baros, Susan Bogus Nov 2020

Bridge Deck Inspection Using Small Unmanned Aircraft Systems Based Airborne Imaging Techniques, Su Zhang, Shirley Baros, Susan Bogus

Data

As one of critical components of a transportation infrastructure system, bridges are very important to a country’s economy because they provide passage over physical obstacles to substantially reduce travel time and travel cost. Similar to other types of transportation infrastructure, bridges deteriorate over time. Therefore, bridges should be routinely inspected to ensure their serviceability, capacity, and safety under current traffic. Subsequently, transportation agencies at all levels (e.g., federal, state, local, and tribal) dedicate large amounts of time and money to routinely monitor and inspect bridge conditions as part of their infrastructure asset management programs. These transportation agencies use the collected …

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Development Of A Low Power, Low Cost Rural Railway Intersection Smart Detection And Warning System, Sara Ahmed, Samer Dessouky, Raymond Downing Nov 2020

Development Of A Low Power, Low Cost Rural Railway Intersection Smart Detection And Warning System, Sara Ahmed, Samer Dessouky, Raymond Downing

Data

This project explores a different approach to provide preemptive warning for train detection at grade-crossings to increase safety and reduce motor vehicle congestion. The development of a novel, low cost, low power, and off rail right-of-way (ROW) detection and warning system will be presented. A background of track circuits, which is the rail industries standard for train detection, will also be provided to highlight the benefits and challenges of the rail industry installing a system at every grade-crossings that lack any type of active warning. The benefits of using thermal imaging instead of traditional video for computer vision will also …

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Bridge Deck Inspection Using Small Unmanned Aircraft Systems Based Airborne Imaging Techniques, Su Zhang, Shirley Baros, Susan Bogus Nov 2020

Bridge Deck Inspection Using Small Unmanned Aircraft Systems Based Airborne Imaging Techniques, Su Zhang, Shirley Baros, Susan Bogus

Publications

As one of critical components of a transportation infrastructure system, bridges are very important to a country’s economy because they provide passage over physical obstacles to substantially reduce travel time and travel cost. Similar to other types of transportation infrastructure, bridges deteriorate over time. Therefore, bridges should be routinely inspected to ensure their serviceability, capacity, and safety under current traffic. Subsequently, transportation agencies at all levels (e.g., federal, state, local, and tribal) dedicate large amounts of time and money to routinely monitor and inspect bridge conditions as part of their infrastructure asset management programs. These transportation agencies use the collected …

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Multivariate Analyses Of Water Quality Dynamics Over Four Decades In The Barataria Basin, Mississippi Delta, John W. Day, Bin Li, Brian D. Marx, Dongran Zhao, Robert Lane Nov 2020

Multivariate Analyses Of Water Quality Dynamics Over Four Decades In The Barataria Basin, Mississippi Delta, John W. Day, Bin Li, Brian D. Marx, Dongran Zhao, Robert Lane

Faculty Publications

No abstract provided.

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A Novel Approach To Assess Metabolic Flexibility Overnight In A Whole-Body Room Calorimeter, David H. Mcdougal, Kara L. Marlatt, Robbie A. Beyl, Leanne M. Redman, Eric Ravussin Nov 2020

A Novel Approach To Assess Metabolic Flexibility Overnight In A Whole-Body Room Calorimeter, David H. Mcdougal, Kara L. Marlatt, Robbie A. Beyl, Leanne M. Redman, Eric Ravussin

Division of Basic Science Faculty Publications

Objective: This study aimed to investigate a novel approach for determining the effects of energy-standardized dinner meals (high-fat and low-fat) on respiratory exchange ratio (RER) dynamics and metabolic flexibility. Methods: Using a randomized crossover study design, energy expenditure, RER, and macronutrient oxidation rates were assessed in response to a single dinner meal during an overnight stay in a whole-body room calorimeter. Eight healthy adults completed two overnight chamber stays while fed either a high-fat (60% fat, 20% carbohydrate [CHO], 20% protein; food quotient [FQ] = 0.784) or low-fat (20% fat, 60% CHO, 20% protein; FQ = 0.899) dinner containing 40% …

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Novel Targets In Glucose Homeostasis And Obesity—Lesson From Rare Mutations, Bing Feng, Pingwen Xu, Yanlin He Nov 2020

Novel Targets In Glucose Homeostasis And Obesity—Lesson From Rare Mutations, Bing Feng, Pingwen Xu, Yanlin He

Division of Basic Science Faculty Publications

Purpose of Review: Obesity and diabetes have already become the second largest risk factor for cardiovascular disease. During the last decade, remarkable advances have been made in understanding the human genome’s contribution to glucose homeostasis disorders and obesity. A few studies on rare mutations of candidate genes provide potential genetic targets for the treatment of diabetes and obesity. In this review, we discussed the detailed findings of these studies and the possible causalities between specific genetic variations and dysfunctions in energy or glucose homeostasis. We are optimistic that novel therapeutic strategies targeting these specific mutants for treating and preventing diabetes …

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Indirect, Non-Thermal Atmospheric Plasma Promotes Bacterial Killing In Vitro And Wound Disinfection In Vivo Using Monogenic And Polygenic Models Of Type 2 Diabetes (Without Adverse Metabolic Complications), Chris R. Cooley, John Mark Mclain, Samuel D. Dupuy, Adrianna E. Eder, Molly Wintenberg, Kimberly Kelly-Wintenberg, Alan Wintenberg, J. Jason Collier, Susan J. Burke, Michael D. Karlstad Nov 2020

Indirect, Non-Thermal Atmospheric Plasma Promotes Bacterial Killing In Vitro And Wound Disinfection In Vivo Using Monogenic And Polygenic Models Of Type 2 Diabetes (Without Adverse Metabolic Complications), Chris R. Cooley, John Mark Mclain, Samuel D. Dupuy, Adrianna E. Eder, Molly Wintenberg, Kimberly Kelly-Wintenberg, Alan Wintenberg, J. Jason Collier, Susan J. Burke, Michael D. Karlstad

Division of Basic Science Faculty Publications

ABSTRACTA novel atmospheric plasma device that uses indirect, non-thermal plasma generated from room air is being studied for its effects on wound disinfection in animal wounds of monogenic and polygenic murine models of type 2 diabetes. As a proof-of-concept report, the goal of this study was to demonstrate the efficacy and safety of the indirect non-thermal plasma (INTP) device in disinfecting polycarbonate filters established with Pseudomonas aeruginosa (PAO1) biofilms as well as wound disinfection in diabetic murine wounds. Dorsal excisional wounds in BALB/c, polygenic TALLYHO, and monogenic db/db mice established with PAO1 infection all demonstrated a 3-log colony-forming unit (CFU) …

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Metabolic Health Status Contributes To Transcriptome Alternation In Human Visceral Adipose Tissue During Obesity, Qiuzhong Zhou, Zhenzhen Fu, Yingyun Gong, Veerabrahma Pratap Seshachalam, Jia Li, Yizhe Ma, Hui Liang, Wei Guan, Shibo Lin, Sujoy Ghosh, Lei Sun, Hongwen Zhou Nov 2020

Metabolic Health Status Contributes To Transcriptome Alternation In Human Visceral Adipose Tissue During Obesity, Qiuzhong Zhou, Zhenzhen Fu, Yingyun Gong, Veerabrahma Pratap Seshachalam, Jia Li, Yizhe Ma, Hui Liang, Wei Guan, Shibo Lin, Sujoy Ghosh, Lei Sun, Hongwen Zhou

Division of Basic Science Faculty Publications

Objective: BMI is a well-established factor affecting the transcriptome profile of adipose tissue, but there are few reports on the relationship between the metabolic health status of people with obesity and the transcriptional changes, particularly in visceral adipose tissue. Methods: Visceral adipose tissue was collected from three subgroups of patients, lean (n = 11), metabolically healthy obesity (MHO; n = 22), and metabolically unhealthy obesity (MUO; n = 26), and RNA sequencing was conducted to profile the transcriptome changes between these groups in a pairwise manner. Results: Comparing MUO with lean and comparing MHO with lean revealed similar patterns in …

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