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Beyond The Boundaries Of Childhood: African American Children In The Antebellum North, Anna Mae Duane Jan 2021

Beyond The Boundaries Of Childhood: African American Children In The Antebellum North, Anna Mae Duane

Civil War Book Review

"Crystal Lynn Webster’s new book, Beyond the Boundaries of Childhood, asks how gradual emancipation in Northern States assigned Black children spaces outside the boundaries of Victorian childhood. Webster also reveals the ways in which Black children were harmed when they were included in reformers’ ideals about childhood, as white reformers felt that Black children’s vulnerability required separation from their families."

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Household War: How Americans Lived And Fought The Civil War, J. Matthew Gallman Jan 2021

Household War: How Americans Lived And Fought The Civil War, J. Matthew Gallman

Civil War Book Review

"This superb collection of essays builds on the central observation that the Civil War was 'a household war.' Households, Lisa Tendrich Frank and LeeAnn Whites explain, were both a “physical place and an ideological construct” that became 'the guiding principle behind many of the war’s causes as well as the impetus for wartime strategies.' In sum, the Civil War was 'a conflict rooted in, fought by, and waged against households.'"

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Christian Citizens: Reading The Bible In Black And White In The Postemancipation South, Shakeel Harris Jan 2021

Christian Citizens: Reading The Bible In Black And White In The Postemancipation South, Shakeel Harris

Civil War Book Review

"Jemison’s concise monograph adds to the field of post-Reconstruction religious history by clearly articulating the impact faith had on the spiritual and civic lives of black and white southerners, and how both recognized the importance of faith in adjusting to changing times. Christian Citizens speaks to the malleability of faith and its ability to define who deserves to rule and be ruled in society."

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Civil War Obscura: Uncle Tom's Cabin; Or, Life Among The Lowly., Meg Groeling Jan 2021

Civil War Obscura: Uncle Tom's Cabin; Or, Life Among The Lowly., Meg Groeling

Civil War Book Review

"Civil War history is more than following battle plans and moving red and blue lines on a map . . . To understand Americans in the 1860s is difficult enough. At least we have Harriet Beecher Stowe to remind us of their complex moral lives and the decisions they made concerning human bondage. For these reasons, Harriet Beecher Stowe's Uncle Tom's Cabin is still worth the read."

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Slavery, Fatherhood, And Paternal Duty In African American Communities Over The Long Nineteenth Century., Kathleen Kennedy Jan 2021

Slavery, Fatherhood, And Paternal Duty In African American Communities Over The Long Nineteenth Century., Kathleen Kennedy

Civil War Book Review

"Overall, Hilde has written a convincing book that adds depth and complexity to the existing literature on enslaved masculinity . . . It thus encourages us to think about the complexities of enslaved men’s experiences and inner life as historians of women have done for enslaved women. Furthermore, the work is accessible as Hilde keeps the stories of enslaved people at the center of her work while deftly framing those stories within a narrative that emphasizes the interrelationships between gender and race in shaping social categories such as fatherhood."

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The Moral Project Of Childhood: Motherhood, Material Life, And Early Children’S Consumer Culture, Paul B. Ringel Jan 2021

The Moral Project Of Childhood: Motherhood, Material Life, And Early Children’S Consumer Culture, Paul B. Ringel

Civil War Book Review

"Perhaps Cook’s most important accomplishment in this book is discarding the perception of a “pre-capitalist” childhood overtaken by rampant commercialism during the nineteenth century. As he notes, the idea of commerce and consumerism acting as a toxic force in childhood is far more common in the literature of the 1980s than it ever was in writings of the 1800s. Such a dichotomy made little sense to nineteenth-century White and prosperous mothers who were focused on teaching their offspring how to engage with goods and money in a manner that would reflect a genteel level of “taste.” Thus, he argues that …

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Search For Long-Duration Gravitational-Wave Signals Associated With Magnetar Giant Flares, A Macquet, M A. Bizouard, E Burns, N Christensen, A Macquet, Z Wadiasingh, G Younes Jan 2021

Search For Long-Duration Gravitational-Wave Signals Associated With Magnetar Giant Flares, A Macquet, M A. Bizouard, E Burns, N Christensen, A Macquet, Z Wadiasingh, G Younes

Faculty Publications

Magnetar giant flares are rare and highly energetic phenomena observed in the transient sky whose emission mechanisms are still not fully understood. Depending on the nature of the excited modes of the magnetar, they are also expected to emit gravitational waves (GWs), which may bring unique information about the dynamics of the excitation. A few magnetar giant flares have been proposed to be associated with short gamma-ray bursts. In this paper we use a new gravitational-wave search algorithm to revisit the possible emission of GWs from four magnetar giant flares within 5 Mpc. While no gravitational-wave signals were observed, we …

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Searches For Continuous Gravitational Waves From 15 Supernova Remnants And Fomalhaut B With Advanced Ligo (Vol 875, 122, 2019), B P. Abbott, R Abbott, T D. Abbott, S Abraham, K Ackley, C Adams, R X. Adhikari, V B. Adya, C Affeldt, M Agathos, K Agatsuma, N Aggarwal, O D. Aguiar, L Aiello, A Ain, P Ajith, G Allen, A Allocca, M A. Aloy, P A. Altin, A Amato, A Ananyeva, S B. Anderson, W. G. Anderson, S V. Angelova, S Antier, S Appert, K Arai, M C. Araya, J S. Areeda, M Arene, N Arnaud, K G. Arun, S. Ascenzi, G. Ashton, S. M. Aston, P. Astone, F. Aubin, P. Aufmuth, K. Aultoneal, C. Austin, V. Avendano, A. Avila-Alvarez, S. Babak, P. Bacon, F. Badaracco, M. K. M. Bader, S. Bae, P. T. Baker, F. Baldaccinni Jan 2021

Searches For Continuous Gravitational Waves From 15 Supernova Remnants And Fomalhaut B With Advanced Ligo (Vol 875, 122, 2019), B P. Abbott, R Abbott, T D. Abbott, S Abraham, K Ackley, C Adams, R X. Adhikari, V B. Adya, C Affeldt, M Agathos, K Agatsuma, N Aggarwal, O D. Aguiar, L Aiello, A Ain, P Ajith, G Allen, A Allocca, M A. Aloy, P A. Altin, A Amato, A Ananyeva, S B. Anderson, W. G. Anderson, S V. Angelova, S Antier, S Appert, K Arai, M C. Araya, J S. Areeda, M Arene, N Arnaud, K G. Arun, S. Ascenzi, G. Ashton, S. M. Aston, P. Astone, F. Aubin, P. Aufmuth, K. Aultoneal, C. Austin, V. Avendano, A. Avila-Alvarez, S. Babak, P. Bacon, F. Badaracco, M. K. M. Bader, S. Bae, P. T. Baker, F. Baldaccinni

Faculty Publications

No abstract provided.

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Anomalies In The Cosmic Microwave Background And Their Non-Gaussian Origin In Loop Quantum Cosmology, I Agullo, D Kranas, V Sreenath Jan 2021

Anomalies In The Cosmic Microwave Background And Their Non-Gaussian Origin In Loop Quantum Cosmology, I Agullo, D Kranas, V Sreenath

Faculty Publications

Anomalies in the cosmic microwave background (CMB) refer to features that have been observed, mostly at large angular scales, and which show some tension with the statistical predictions of the standard ?CDM model. In this work, we focus our attention on power suppression, dipolar modulation, a preference for odd parity, and the tension in the lensing parameter A ( L ). Though the statistical significance of each individual anomaly is inconclusive, collectively they are significant, and could indicate new physics beyond the ?CDM model. In this article, we present a brief, but pedagogical introduction to CMB anomalies and propose a …

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Fast-Transient Searches In Real Time With Ztfrest: Identification Of Three Optically Discovered Gamma-Ray Burst Afterglows And New Constraints On The Kilonova Rate, Igor Andreoni, Michael W. Coughlin2, Erik C. Kool, Mansi M. Kasliwal, Harsh Kumar, Varun Bhalerao, Ana Sagues Carracedo, Anna Y. Q. Ho, Peter T. Pang, Divita Saraogi, Kritti Sharma, Vedant Shenoy, Eric Burns, Tomas Ahumada, Shreya Anand, Leo P. Singer, Daniel A. Perley, Kishalay De, U. C. Fremling, Eric C. Bellm, Mattia Bulla, Arien Crellin-Quick, Tim Dietrich, Andrew Drake, Dmitry A. Duev, Ariel Goobar, Matthew J. Graham, David L. Kaplan, S. R. Kulkarni, Russ R. Laher, Ashish A. Mahabal, David L. Shupe, Jesper Sollerman, Richard Walters, Yuhan Yao Jan 2021

Fast-Transient Searches In Real Time With Ztfrest: Identification Of Three Optically Discovered Gamma-Ray Burst Afterglows And New Constraints On The Kilonova Rate, Igor Andreoni, Michael W. Coughlin2, Erik C. Kool, Mansi M. Kasliwal, Harsh Kumar, Varun Bhalerao, Ana Sagues Carracedo, Anna Y. Q. Ho, Peter T. Pang, Divita Saraogi, Kritti Sharma, Vedant Shenoy, Eric Burns, Tomas Ahumada, Shreya Anand, Leo P. Singer, Daniel A. Perley, Kishalay De, U. C. Fremling, Eric C. Bellm, Mattia Bulla, Arien Crellin-Quick, Tim Dietrich, Andrew Drake, Dmitry A. Duev, Ariel Goobar, Matthew J. Graham, David L. Kaplan, S. R. Kulkarni, Russ R. Laher, Ashish A. Mahabal, David L. Shupe, Jesper Sollerman, Richard Walters, Yuhan Yao

Faculty Publications

The most common way to discover extragalactic fast transients, which fade within a few nights in the optical, is via follow-up of gamma-ray burst and gravitational-wave triggers. However, wide-field surveys have the potential to identify rapidly fading transients independently of such external triggers. The volumetric survey speed of the Zwicky Transient Facility (ZTF) makes it sensitive to objects as faint and fast fading as kilonovae, the optical counterparts to binary neutron star mergers, out to almost 200 Mpc. We introduce an open-source software infrastructure, the ZTF REaltime Search and Triggering, ZTFReST, designed to identify kilonovae and fast transients in ZTF …

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Discovering Features In Gravitational-Wave Data Through Detector Characterization, Citizen Science And Machine Learning, S Soni, C P. Berry, S B. Coughlin, M Harandi, S Soni, K Crowston, C Osterlund, O Patane, A K. Katsaggelos, L Trouille, V G. Baranowski, W F. Domainko, K Kaminski, M A. Rodriguez, U Marciniak, P Nauta, G Niklasch, R R. Rote, B Teglas, C Unsworth, C Zhang Jan 2021

Discovering Features In Gravitational-Wave Data Through Detector Characterization, Citizen Science And Machine Learning, S Soni, C P. Berry, S B. Coughlin, M Harandi, S Soni, K Crowston, C Osterlund, O Patane, A K. Katsaggelos, L Trouille, V G. Baranowski, W F. Domainko, K Kaminski, M A. Rodriguez, U Marciniak, P Nauta, G Niklasch, R R. Rote, B Teglas, C Unsworth, C Zhang

Faculty Publications

The observation of gravitational waves is hindered by the presence of transient noise (glitches). We study data from the third observing run of the Advanced LIGO detectors, and identify new glitch classes: fast scattering/crown and low-frequency blips. Using training sets assembled by monitoring of the state of the detector, and by citizen-science volunteers, we update the Gravity Spy machine-learning algorithm for glitch classification. We find that fast scattering/crown, linked to ground motion at the detector sites, is especially prevalent, and identify two subclasses linked to different types of ground motion. Reclassification of data based on the updated model finds that …

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Reducing Scattered Light In Ligo's Third Observing Run, S. Soni, C. Austin, A. Effler, R. M.S. Schofield, G. González, V. V. Frolov, J. C. Driggers, A. Pele, A. L. Urban, G. Valdes, R. Abbott, C. Adams, R. X. Adhikari, A. Ananyeva, S. Appert, K. Arai, J. S. Areeda, Y. Asali, S. M. Aston, A. M. Baer, M. Ball, S. W. Ballmer, S. Banagiri, D. Barker, L. Barsotti, J. Bartlett, B. K. Berger, J. Betzwieser, D. Bhattacharjee, G. Billingsley, S. Biscans, C. D. Blair, R. M. Blair Jan 2021

Reducing Scattered Light In Ligo's Third Observing Run, S. Soni, C. Austin, A. Effler, R. M.S. Schofield, G. González, V. V. Frolov, J. C. Driggers, A. Pele, A. L. Urban, G. Valdes, R. Abbott, C. Adams, R. X. Adhikari, A. Ananyeva, S. Appert, K. Arai, J. S. Areeda, Y. Asali, S. M. Aston, A. M. Baer, M. Ball, S. W. Ballmer, S. Banagiri, D. Barker, L. Barsotti, J. Bartlett, B. K. Berger, J. Betzwieser, D. Bhattacharjee, G. Billingsley, S. Biscans, C. D. Blair, R. M. Blair

Faculty Publications

Noise due to scattered light has been a frequent disturbance in the advanced LIGO gravitational wave detectors, hindering the detection of gravitational waves. The non stationary scatter noise caused by low frequency motion can be recognized as arches in the time-frequency plane of the gravitational wave channel. In this paper, we characterize the scattering noise for LIGO and Virgo's third observing run O3 from April, 2019 to March, 2020. We find at least two different populations of scattering noise and we investigate the multiple origins of one of them as well as its mitigation. We find that relative motion between …

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Open Data From The First And Second Observing Runs Of Advanced Ligo And Advanced Virgo, R. Abbott, T. D. Abbott, S. Abraham, F. Acernese, K. Ackley, C. Adams, R. X. Adhikari, V. B. Adya, C. Affeldt, M. Agathos, K. Agatsuma, N. Aggarwal, O. D. Aguiar, A. Aich, L. Aiello, A. Ain, P. Ajith, G. Allen, A. Allocca, P. A. Altin, A. Amato, S. Anand, A. Ananyeva, S. B. Anderson, W. G. Anderson, S. V. Angelova, S. Ansoldi, S. Antier, S. Appert, K. Arai, M. C. Araya, J. S. Areeda, M. Arène Jan 2021

Open Data From The First And Second Observing Runs Of Advanced Ligo And Advanced Virgo, R. Abbott, T. D. Abbott, S. Abraham, F. Acernese, K. Ackley, C. Adams, R. X. Adhikari, V. B. Adya, C. Affeldt, M. Agathos, K. Agatsuma, N. Aggarwal, O. D. Aguiar, A. Aich, L. Aiello, A. Ain, P. Ajith, G. Allen, A. Allocca, P. A. Altin, A. Amato, S. Anand, A. Ananyeva, S. B. Anderson, W. G. Anderson, S. V. Angelova, S. Ansoldi, S. Antier, S. Appert, K. Arai, M. C. Araya, J. S. Areeda, M. Arène

Faculty Publications

Advanced LIGO and Advanced Virgo are monitoring the sky and collecting gravitational-wave strain data with sufficient sensitivity to detect signals routinely. In this paper we describe the data recorded by these instruments during their first and second observing runs. The main data products are gravitational-wave strain time series sampled at 16384 Hz. The datasets that include this strain measurement can be freely accessed through the Gravitational Wave Open Science Center at http://gw-openscience.org, together with data-quality information essential for the analysis of LIGO and Virgo data, documentation, tutorials, and supporting software.

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Global Sex Disparity Of Covid-19: A Descriptive Review Of Sex Hormones And Consideration For The Potential Therapeutic Use Of Hormone Replacement Therapy In Older Adults, S C. Okpechi, J T. Fong, S S. Gill, J C. Harman, S C. Okpechi, Q C. Chukwurah, I O. Onor, S K. Alahari Jan 2021

Global Sex Disparity Of Covid-19: A Descriptive Review Of Sex Hormones And Consideration For The Potential Therapeutic Use Of Hormone Replacement Therapy In Older Adults, S C. Okpechi, J T. Fong, S S. Gill, J C. Harman, S C. Okpechi, Q C. Chukwurah, I O. Onor, S K. Alahari

Faculty Publications

The 2019-2020 SARS-related coronavirus-2 (SARS-CoV-2) pandemic has brought unprecedented challenges to healthcare sectors around the world. As of November 2020, there have been over 64 million confirmed cases and approaching 2 million deaths globally. Despite the large number of positive cases, there are very limited established standards of care and therapeutic options available. To date, there is still no Food and Drug Administration (FDA) approved vaccine for COVID-19, although there are several options in various clinical trial stages. Herein, we have performed a global review evaluating the roles of age and sex on COVID-19 hospitalizations, ICU admissions, deaths in hospitals, …

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Bats And Humans During Thesars-Cov-2outbreak: The Case Of Bat-Coronaviruses From Mexico, P Colunga-Salas, G Hernandez-Canchola Jan 2021

Bats And Humans During Thesars-Cov-2outbreak: The Case Of Bat-Coronaviruses From Mexico, P Colunga-Salas, G Hernandez-Canchola

Faculty Publications

The novelSARS-CoV-2coronavirus has attracted attention due to the high number of human cases around the world. It has been proposed that this virus originated in bats, possibly transmitted to humans by an intermediate host, making bats a group of great interest during this outbreak. Almost 10% of the world's bat species inhabit Mexico, and 14 previous novel CoVs have been recorded in Mexican bats. However, the phylogenetic relationships between these viruses and the novel coronavirus are unknown. The aim of this communication was therefore to describe the phylogenetic relationships between Mexican bat-CoVs andSARS-CoV-2. We showed that Mexican bat-CoVs sequences are …

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Physical Education Teachers' Experiences With Remote Instruction During The Initial Phase Of The Covid-19 Pandemic, K Mercier, E Centeio, A Garn, H Erwin, K Mercier, J Foley Jan 2021

Physical Education Teachers' Experiences With Remote Instruction During The Initial Phase Of The Covid-19 Pandemic, K Mercier, E Centeio, A Garn, H Erwin, K Mercier, J Foley

Faculty Publications

This study investigated physical education (PE) teachers' experiences with remote instruction in the United States during the initial outbreak of COVID-19. PE teachers (n = 4,362) from all 50 states completed a survey identifying their experiences with remote instruction in May, 2020. Survey responses were analyzed by geographic region, district type, and school level. Teachers reported having students submit assignments (51% yes), using video instruction (37% yes), being less effective when instructing remotely (20% yes), and emphasizing student outcomes focused on health-related fitness (32% yes), and physical activity value/ enjoyment (43% yes). Access to technology (40% yes) and required student …

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The Effectiveness Of Image Augmentation In Deep Learning Networks For Detecting Covid-19: A Geometric Transformation Perspective, M Elgendi, M U. Nasir, Q F. Tang, D Smith, M Elgendi, C Batte, B Spieler, W D. Leslie, C Menon, R R. Fletcher, N Howard, R Ward, W Parker, S Nicolaou Jan 2021

The Effectiveness Of Image Augmentation In Deep Learning Networks For Detecting Covid-19: A Geometric Transformation Perspective, M Elgendi, M U. Nasir, Q F. Tang, D Smith, M Elgendi, C Batte, B Spieler, W D. Leslie, C Menon, R R. Fletcher, N Howard, R Ward, W Parker, S Nicolaou

Faculty Publications

Chest X-ray imaging technology used for the early detection and screening of COVID-19 pneumonia is both accessible worldwide and affordable compared to other non-invasive technologies. Additionally, deep learning methods have recently shown remarkable results in detecting COVID-19 on chest X-rays, making it a promising screening technology for COVID-19. Deep learning relies on a large amount of data to avoid overfitting. While overfitting can result in perfect modeling on the original training dataset, on a new testing dataset it can fail to achieve high accuracy. In the image processing field, an image augmentation step (i.e., adding more training data) is often …

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The Interplay Between Environmental Exposures And Covid-19 Risks In The Health Of Children, P D. Sly, B A. Trottier, C M. Bulka, S A. Cormier, P D. Sly, R C. Fry, K W. Kim, S Kleeberger, P Kumar, P J. Landrigan, K L. Carlsen, A Pascale, F Polack, M Ruchirawat, H J. Zar, W A. Suk Jan 2021

The Interplay Between Environmental Exposures And Covid-19 Risks In The Health Of Children, P D. Sly, B A. Trottier, C M. Bulka, S A. Cormier, P D. Sly, R C. Fry, K W. Kim, S Kleeberger, P Kumar, P J. Landrigan, K L. Carlsen, A Pascale, F Polack, M Ruchirawat, H J. Zar, W A. Suk

Faculty Publications

Background: An unusual feature of SARS-Cov-2 infection and the COVID-19 pandemic is that children are less severely affected than adults. This is especially paradoxical given the epidemiological links between poor air quality and increased COVID-19 severity in adults and that children are generally more vulnerable than adults to the adverse consequences of air pollution. Objectives: To identify gaps in knowledge about the factors that protect children from severe SARS-Cov-2 infection even in the face of air pollution, and to develop a transdisciplinary research strategy to address these gaps. Methods: An international group of researchers interested in children's environmental health was …

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The Impact Of Covid-19 On Consumer Food Wastejel Codes, B E. Roe, K Bender, D Y. Qi Jan 2021

The Impact Of Covid-19 On Consumer Food Wastejel Codes, B E. Roe, K Bender, D Y. Qi

Faculty Publications

Perhaps no phenomenon has so quickly and radically altered household production parameters and daily food patterns as the onset of the COVID-19 pandemic. We contemplate the immediate and longer-term implications of this public health crisis on the amount of food wasted by consumers. We conclude that the pandemic and its aftermath may improve household skills and management practices in a manner that reduces day-to-day household food waste. However, pandemic-driven disruptions may induce larger intermittent purges of food due to changes in work patterns and food service and food retailing availability. We recommend several steps to reduce waste as the pandemic …

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Btk/Itk Dual Inhibitors: Modulating Immunopathology And Lymphopenia For Covid-19 Therapy, M C. Mcgee, A August, W S. Huang Jan 2021

Btk/Itk Dual Inhibitors: Modulating Immunopathology And Lymphopenia For Covid-19 Therapy, M C. Mcgee, A August, W S. Huang

Faculty Publications

Bruton's tyrosine kinase (BTK) signaling is involved in innate immune responses and regulates the production of proinflammatory cytokines that can contribute to COVID-19 immunopathology. Clinical trials with BTK inhibitors in COVID-19 treatment have been proposed, and previous studies have attempted to investigate the therapeutic effects of ibrutinib and underlying mechanisms in treating viral pneumonia. These attempts, however, did not consider potential off target effect of BTK inhibitors on T cell differentiation, function, and survival, which may be beneficial in treatment for COVID-19. Here, we summarize the current knowledge of BTK/IL-2-inducible T-cell kinase (ITK) signaling in immunopathology and lymphopenia and discuss …

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Telehealth And Autism Prior To And In The Age Of Covid-19: A Systematic And Critical Review Of The Last Decade, K S. Ellison, J Guidry, P Picou, P Adenuga, K S. Ellison Jan 2021

Telehealth And Autism Prior To And In The Age Of Covid-19: A Systematic And Critical Review Of The Last Decade, K S. Ellison, J Guidry, P Picou, P Adenuga, K S. Ellison

Faculty Publications

There has been growing interest in the use of telehealth; however, the COVID-19 pandemic and the subsequent isolation and restrictions placed on in-person services have fast-tracked implementation needs for these services. Individuals with autism spectrum disorder (ASD) have been particularly affected due to the often-intensive service needs required by this population. As a result, the aim of this review was to examine the evidence base, methodology, and outcomes of studies that have used telehealth for assessment and/or intervention with children and adolescents with ASD as well as their families over the last decade. Further, the goal is to highlight the …

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Experimental Re-Infected Cats Do Not Transmit Sars-Cov-2, N N. Gaudreault, M Carossino, I Morozov, J D. Trujillo, N N. Gaudreault, D W. Madden, K Cool, B L. Artiaga, C Mcdowell, D Bold, V Balaraman, T Kwon, W J. Ma, J Henningson, D W. Wilson, W C. Wilson, U C. Balasuriya, A Garcia-Sastre, J A. Richt Jan 2021

Experimental Re-Infected Cats Do Not Transmit Sars-Cov-2, N N. Gaudreault, M Carossino, I Morozov, J D. Trujillo, N N. Gaudreault, D W. Madden, K Cool, B L. Artiaga, C Mcdowell, D Bold, V Balaraman, T Kwon, W J. Ma, J Henningson, D W. Wilson, W C. Wilson, U C. Balasuriya, A Garcia-Sastre, J A. Richt

Faculty Publications

SARS-CoV-2 is the causative agent of COVID-19 and responsible for the current global pandemic. We and others have previously demonstrated that cats are susceptible to SARS-CoV-2 infection and can efficiently transmit the virus to naive cats. Here, we address whether cats previously exposed to SARS-CoV-2 can be re-infected with SARS-CoV-2. In two independent studies, SARS-CoV-2-infected cats were re-challenged with SARS-CoV-2 at 21 days post primary challenge (DPC) and necropsies performed at 4, 7 and 14 days post-secondary challenge (DP2C). Sentinels were co-mingled with the re-challenged cats at 1 DP2C. Clinical signs were recorded, and nasal, oropharyngeal, and rectal swabs, blood, …

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Online-Delivered Group And Personal Exercise Programs To Support Low Active Older Adults' Mental Health During The Covid-19 Pandemic: Randomized Controlled Trial, M R. Beauchamp, R M. Hulteen, G R. Ruissen, Y Liu, M R. Beauchamp, C M. Wierts, K J. Waldhauser, S H. Harden, E Puterman Jan 2021

Online-Delivered Group And Personal Exercise Programs To Support Low Active Older Adults' Mental Health During The Covid-19 Pandemic: Randomized Controlled Trial, M R. Beauchamp, R M. Hulteen, G R. Ruissen, Y Liu, M R. Beauchamp, C M. Wierts, K J. Waldhauser, S H. Harden, E Puterman

Faculty Publications

Background: In response to the COVID-19 pandemic, experts in mental health science emphasized the importance of developing and evaluating approaches to support and maintain the mental health of older adults. Objective: The aim of this study was to assess whether a group-based exercise program relative to a personal exercise program (both delivered online) and waitlist control (WLC) can improve the psychological health of previously low active older adults during the early stages of the COVID-19 pandemic. Methods: The Seniors COVID-19 Pandemic and Exercise (SCOPE) trial was a 3-arm, parallel randomized controlled trial conducted between May and September 2020 in which …

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Increases In Distress During Stay-At-Home Mandates During The Covid-19 Pandemic: A Longitudinal Study, J D. Buckner, C N. Abarno, E M. Lewis, M J. Zvolensky, J D. Buckner Jan 2021

Increases In Distress During Stay-At-Home Mandates During The Covid-19 Pandemic: A Longitudinal Study, J D. Buckner, C N. Abarno, E M. Lewis, M J. Zvolensky, J D. Buckner

Faculty Publications

The Coronavirus disease 2019 (COVID-19) pandemic has contributed to over 500,000 deaths, and hospitalization of thousands of individuals worldwide. Cross-sectional data indicate that anxiety and depression levels are greater during the pandemic, yet no known prospective studies have tested this assertion. Further, individuals with elevated trait anxiety prior to a global pandemic may theoretically be more apt to experience greater pandemic-related anxiety and/or impairment. The current study tested whether anxiety and depression increased from the month before the state?s Stay-At-Home order to the period of the Stay-At-Home order among 120 young adults in Louisiana, a state with especially high rates …

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Cognitive Disorders Associated With Hospitalization Of Covid-19: Results From An Observational Cohort Study, J Q. Zhou, C Liu, Y T. Sun, W S. Huang, J Q. Zhou Jan 2021

Cognitive Disorders Associated With Hospitalization Of Covid-19: Results From An Observational Cohort Study, J Q. Zhou, C Liu, Y T. Sun, W S. Huang, J Q. Zhou

Faculty Publications

Introduction: Our understanding of risk factors for COVID-19, including pre-existing medical conditions and genetic variations, is limited. To what extent the pre-existing clinical condition and genetic background have implications for COVID-19 still needs to be explored. Methods: Our study included 389,620 participants of European descent from the UK Biobank, of whom 3,884 received the COVID-19 test and 1,091 were tested positive for COVID-19. We examined the association of COVID-19 status with an extensive list of 974 medical conditions and 30 blood biomarkers. Additionally, we tested the association of genetic variants in two key genes related to severe acute respiratory syndrome …

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Top1 Inhibition Therapy Protects Against Sars-Cov-2-Induced Lethal Inflammation, J S. Ho, B W. Mok, L Campisi, T Jordan, J S. Ho, S Parameswaran, J A. Wayman, N N. Gaudreault, D A. Meekins, S V. Indran, I Morozov, J D. Trujillo, Y S. Fstkchyan, R Rathnasinghe, Z Y. Zhu, S M. Zheng, N M. Zhao, K White, H Ray-Jones, V Malysheva, M J. Thiecke, S Y. Lau, H L. Liu, A N. Zhang, S Lee, W C. Liu, S Jangra, A Escalera, T Aydillo, B S. Melo, E Guccione, R Sebra, E Shum, J Bakker Jan 2021

Top1 Inhibition Therapy Protects Against Sars-Cov-2-Induced Lethal Inflammation, J S. Ho, B W. Mok, L Campisi, T Jordan, J S. Ho, S Parameswaran, J A. Wayman, N N. Gaudreault, D A. Meekins, S V. Indran, I Morozov, J D. Trujillo, Y S. Fstkchyan, R Rathnasinghe, Z Y. Zhu, S M. Zheng, N M. Zhao, K White, H Ray-Jones, V Malysheva, M J. Thiecke, S Y. Lau, H L. Liu, A N. Zhang, S Lee, W C. Liu, S Jangra, A Escalera, T Aydillo, B S. Melo, E Guccione, R Sebra, E Shum, J Bakker

Faculty Publications

The ongoing pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is currently affecting millions of lives worldwide. Large retrospective studies indicate that an elevated level of inflammatory cytokines and pro-inflammatory factors are associated with both increased disease severity and mortality. Here, using multidimensional epigenetic, transcriptional, in vitro, and in vivo analyses, we report that topoisomerase 1 (TOP1) inhibition suppresses lethal inflammation induced by SARS-CoV-2. Therapeutic treatment with two doses of topotecan (TPT), an FDA-approved TOP1 inhibitor, suppresses infection-induced inflammation in hamsters. TPT treatment as late as 4 days post-infection reduces morbidity and rescues mortality in a transgenic mouse …

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The Infrared Evolution Of Dust In V838 Monocerotis, C E. Woodward, A Evans, D P. Banerjee, T Liimets, C E. Woodward, S Starrfield, G C. Clayton, S P. Eyres, R D. Gehrz, R M. Wagner Jan 2021

The Infrared Evolution Of Dust In V838 Monocerotis, C E. Woodward, A Evans, D P. Banerjee, T Liimets, C E. Woodward, S Starrfield, G C. Clayton, S P. Eyres, R D. Gehrz, R M. Wagner

Faculty Publications

Luminous Red Variables are most likely eruptions that are the outcome of stellar mergers. V838 Mon is one of the best-studied members of this class, representing an archetype for stellar mergers resulting from B-type stars. As result of the merger event, nova-like eruptions occur driving mass loss from the system. As the gas cools considerable circumstellar dust is formed. V838 Mon erupted in 2002 and is undergoing very dynamic changes in its dust composition, geometry, and infrared luminosity providing a real-time laboratory to validate mineralogical condensation sequences in stellar mergers and evolutionary scenarios. We discuss recent NASA Stratospheric Observatory for …

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Spitzer's Last Look At Extragalactic Explosions: Long-Term Evolution Of Interacting Supernovae, T Szalai, O D. Fox, R G. Arendt, E Dwek, T Szalai, G C. Clayton, A V. Filippenko, J Johansson, P L. Kelly, K Krafton, A P. Marston, J C. Mauerhan, D Y. Van, Sd Jan 2021

Spitzer's Last Look At Extragalactic Explosions: Long-Term Evolution Of Interacting Supernovae, T Szalai, O D. Fox, R G. Arendt, E Dwek, T Szalai, G C. Clayton, A V. Filippenko, J Johansson, P L. Kelly, K Krafton, A P. Marston, J C. Mauerhan, D Y. Van, Sd

Faculty Publications

Here we present new, yet final, mid-infrared (mid-IR) data for supernovae (SNe) based on measurements with the Spitzer Space Telescope. Comparing our recent 3.6 and 4.5 mu m photometry with previously published mid-IR and further multiwavelength data sets, we were able to draw some conclusions about the origin and heating mechanism of the dust in these SNe or in their environments, as well as about possible connection with circumstellar matter (CSM) originating from pre-explosion mass-loss events in the progenitor stars. We also present new results regarding both certain SN classes and single objects. We highlight the mid-IR homogeneity of SNe …

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All-Sky Search For Continuous Gravitational Waves From Isolated Neutron Stars In The Early O3 Ligo Data, R Abbott, T D. Abbott, S Abraham, F Acernese, R Abbott, A Adams, C Adams, R X. Adhikari, V B. Adya, C Affeldt, D Agarwal, M Agathos, K Agatsuma, N Aggarwal, O D. Aguiar, L Aiello, A Ain, P Ajith, T Akutsu, K M. Aleman, G Allen, A Allocca, P A. Altin, A Amato, S B. Anand, A Ananyeva, S B. Anderson, W G. Anderson, M Ando, S V. Angelova, S Ansoldi, J M. Antelis, S Antier, S Appert Jan 2021

All-Sky Search For Continuous Gravitational Waves From Isolated Neutron Stars In The Early O3 Ligo Data, R Abbott, T D. Abbott, S Abraham, F Acernese, R Abbott, A Adams, C Adams, R X. Adhikari, V B. Adya, C Affeldt, D Agarwal, M Agathos, K Agatsuma, N Aggarwal, O D. Aguiar, L Aiello, A Ain, P Ajith, T Akutsu, K M. Aleman, G Allen, A Allocca, P A. Altin, A Amato, S B. Anand, A Ananyeva, S B. Anderson, W G. Anderson, M Ando, S V. Angelova, S Ansoldi, J M. Antelis, S Antier, S Appert

Faculty Publications

We report on an all-sky search for continuous gravitational waves in the frequency band 20-2000 Hz and with a frequency time derivative in the range of [-1.0; +0.1] x 10(-8) Hz/s. Such a signal could be produced by a nearby, spinning and slightly nonaxisymmetric isolated neutron star in our Galaxy. This search uses the LIGO data from the first six months of Advanced LIGO's and Advanced Virgo's third observational run, O3. No periodic gravitational wave signals are observed, and 95% confidence-level (C.L.) frequentist upper limits are placed on their strengths. The lowest upper limits on worst-case (linearly polarized) strain amplitude …

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Kepler K2 Campaign 9-I. Candidate Short-Duration Events From The First Space-Based Survey For Planetary Microlensing, I Mcdonald, E Kerins, R Poleski, M T. Penny, I Mcdonald, S Mao, P Fouque, W Zhu, W Zang Jan 2021

Kepler K2 Campaign 9-I. Candidate Short-Duration Events From The First Space-Based Survey For Planetary Microlensing, I Mcdonald, E Kerins, R Poleski, M T. Penny, I Mcdonald, S Mao, P Fouque, W Zhu, W Zang

Faculty Publications

We present the first short-duration candidate microlensing events from the Kepler K2 mission. From late April to early July 2016, Campaign 9 of K2 obtained high temporal cadence observations over a 3.7 deg(2) region of the Galactic bulge. Its primary objectives were to look for evidence of a free-floating planet (FFP) population using microlensing, and demonstrate the feasibility of space-based planetary microlensing surveys. Though Kepler K2 is far from optimal for microlensing, the recently developed MCPM photometric pipeline enables us to identify and model microlensing events. We describe our blind event-selection pipeline in detail and use it to recover 22 …

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