Digital Commons Network^™

Assessment Of The Effect Of Acepromazine On Insulin Tolerance Tests (Itt) In Dairy Heifers, Mya Catherine Orantes

Honors Capstones

No abstract provided.

Conformational Change And The Effects Of A Substrate Mimetic On 5-Lipoxygenase, Mathes Akers Prometheus Forge

Honors Capstones

No abstract provided.

A Rapid Species-Specific Diagnostic Assay For Xylaria Necrophora, The Pathogen Behind Taproot Decline Of Soybean In The Southern United States, Sophie Baron Sheffield

Honors Capstones

No abstract provided.

Psychological Well-Being In The Years After A Flood And During A Pandemic, Angelina Cantelli

Honors Capstones

No abstract provided.

Ux/U-Eye: Designing Graphical User Interfaces For Exclusive Eye Gaze Control, Timothy Curol

Honors Capstones

No abstract provided.

A Sleeping Giant: Finding An Endogenous Solution For The U.S. Public Pension Underfunding Crisis, Caroline Crawford

Honors Capstones

No abstract provided.

Attitudes, Purchases, And Usage Of Lingerie Among College Women: An Exploratory Investigation, Madison Craig

Honors Capstones

No abstract provided.

Urination And Aggravation: Status-Relevant Visual And Chemosensory Signals Escalate Aggressive Interactions In An African Cichlid Fish, Evan J. Dorè

Honors Capstones

No abstract provided.

Illusory Effects On Stepping Over Obstacles After Lower Extremity Muscle Fatigue, Abayomi Gideon Adeyemo

Honors Capstones

No abstract provided.

The Effects Of Media Representation On Black Civic Engagement & Media Usage, Charity Williams

Honors Capstones

No abstract provided.

Early Foundational Cultures Of Modern Spain, Emily Webre

Honors Capstones

No abstract provided.

Being Black Is A Crime: An Examination Of The Historical Use Of Racist Rhetoric To Maintain The Mass Criminalization Of Black People, Charlisse Walters

Honors Capstones

No abstract provided.

Tales From Ladouleur: Fictive Grief And Blackness Through The Lens Of Fairytales, Exquisite Williams

Honors Capstones

No abstract provided.

Dynamic Design And Simulation Of Mechanical Baseball Launcher, Camille Wetekamm

Honors Capstones

No abstract provided.

Led Enhancements To The Mimir Animatronic Figure, Collin J. Devillier

Honors Capstones

No abstract provided.

Democracy’S Effect On Attributes Of Transnational Terrorism, Alice Epley

Honors Capstones

No abstract provided.

Influence Of Cavs On Driver’S Decisions In Various Roadway Scenarios, Nathalie Joy Taboga Dante

Honors Capstones

No abstract provided.

Pharmacological Extension Of Lifespan Via Mitochondrial Uncoupling In Drosophila Melanogaster, Analisa Taylor

Honors Capstones

No abstract provided.

Constraints On Dark Photon Dark Matter Using Data From Ligo's And Virgo's Third Observing Run, R. Abbott

Faculty Publications

We present a search for dark photon dark matter that could couple to gravitational-wave interferometers using data from Advanced LIGO and Virgo's third observing run. To perform this analysis, we use two methods, one based on cross-correlation of the strain channels in the two nearly aligned LIGO detectors, and one that looks for excess power in the strain channels of the LIGO and Virgo detectors. The excess power method optimizes the Fourier transform coherence time as a function of frequency, to account for the expected signal width due to Doppler modulations. We do not find any evidence of dark photon …

Are Long-Period Exoplants Around Cool Stars More Common Than We Thought?, Emily Jane Safron

LSU Doctoral Dissertations

The Kepler mission has been the catalyst for discovery of nearly 5,000 confirmed and candidate exoplanets. The majority of these candidates orbit Sun-like stars, and have orbital periods comparable to or shorter than that of the Earth, due to the selection bias inherent in the transit method and the limitations of automated transit search algorithms. We aim to develop a richer understanding of the population of exoplanets around the lowest-mass stars, the M spectral type. We are particularly interested in exoplanets with long orbital periods, which are difficult or impossible to find using standard transit search algorithms. In our study, …

Bipse: A Biomarker-Based Phase I/Ii Design For Immunotherapy Trials With Progression-Free Survival Endpoint, Beibei Guo, Yong Zang

Faculty Publications

A Bayesian biomarker-based phase I/II design (BIPSE) is presented for immunotherapy trials with a progression-free survival (PFS) endpoint. The objective is to identify the subgroup-specific optimal dose, defined as the dose with the best risk-benefit tradeoff in each biomarker subgroup. We jointly model the immune response, toxicity outcome, and PFS with information borrowing across subgroups. A plateau model is used to describe the marginal distribution of the immune response. Conditional on the immune response, we model toxicity using probit regression and model PFS using the mixture cure rate model. During the trial, based on the accumulating data, we continuously update …

Pharmakon In The Firelands: Connecting Historical Discourses And Small-Town Social Contexts With Substance Use Experience, Andrew Robert Burns

LSU Doctoral Dissertations

The ongoing increase in opioid and polysubstance-related overdoses and mortality in United States coincides with a shift in the ways substance use is understood. Once almost exclusively treated as a criminal problem, substance use, and overdose is increasingly viewed in terms of public health and from an urban to rural issue. The discourse surrounding the use of psychoactive substances largely omits the voices of the very people who use them. Likewise, the social context of small towns, at once not quite rural nor entirely urban, is generally given little consideration. To address these gaps in the research, I conduct two …

Performance Analysis And Improvement For Scalable And Distributed Applications Based On Asynchronous Many-Task Systems, Nanmiao Wu

LSU Doctoral Dissertations

As the complexity of recent and future large-scale data and exascale systems architectures grows, so do productivity, portability, software scalability, and efficient utilization of system resources challenges presented to both industry and the research community. Software solutions and applications are expected to scale in performance on such complex systems. Asynchronous many-task (AMT) systems, taking advantage of multi-core architectures with light-weight threads, asynchronous executions, and smart scheduling, are showing promise in addressing these challenges.

In this research, we implement several scalable and distributed applications based on HPX, an exemplar AMT runtime system. First, a distributed HPX implementation for a parameterized benchmark …

Essays On Intersection Of Economics And Judicial Decision-Making, Masoud Asadi

LSU Doctoral Dissertations

This dissertation consists of two chapters on the economics of judicial decision-making. In chapter 2, using the data from U.S. immigration courts and the Global Terrorism Dataset, I investigate the effect of terrorist attacks on asylum decisions. I find that terrorist attacks within the courts' states reduce the likelihood of granting asylums by 1.9 percent. This effect is driven by Islamic, Right-wing, and Lone-wolf terrorist attacks, and the magnitude of the effect is largest in the case of Islamic terrorist attacks (3.6 %) and smallest in the case of Lone-wolf attacks (1.9 %). Left-wing terrorist attacks have no impact on …

Synthesis Of Thiol-Acrylate Hydrogels For 3d Cell Culture And Microfluidic Applications, Anowar Hossain Khan

LSU Doctoral Dissertations

Globally cell culture is an $18.98 billion industry as of 2020, with an 11.6 percent annual growth rate. Drug discovery has an estimated worth of $69.8 billion in 2020 and is predicted to grow to $110.4 billion by 2025. Three-dimensional (3D) cell culture of cancer cells is one of the rapidly growing felids since it better recapitulates in vivo conditions compared to two-dimensional (2D) models. However, it is challenging to grow 3D tumor spheroids outside the body, and some of the existing technology can generate these spheroids outside the human body but poorly mimic in vivo tumor models. Therefore, there …

Novel Roles For Viral Gpcrs In Cmv Latency And Immunity, Timothy White

LSU Doctoral Dissertations

Human cytomegalovirus (HCMV) is a widespread, highly prevalent pathogen with severe consequences in vulnerable populations. HCMV and the related murine cytomegalovirus (MCMV) encode multiple G protein-coupled receptor (GPCR) homologs which are involved in latency, immune evasion, and tissue tropism and dissemination. In this work, we investigate the mechanisms of two CMV-encoded GPCR homologs, HCMV US28 and MCMV M33, in latency and T cell immune evasion. Chapter 2 describes the isolation and immortalization of a salivary gland-derived mesenchymal cell line, termed mSGM. These cells are permissive to MCMV infection and express all three BALB/c mouse MHC class I isotypes, making them …

Visuomotor Rotation Adaptation And Workspace Manipulation: A Behavioral And Cognitive Emphasis, Reuben N. Addison

LSU Doctoral Dissertations

This is a three-study dissertation in which we aimed to broaden our knowledge of the mechanisms contributing to a 45° clockwise visuomotor adaptation by including variations in workspace. We provide behavioral and in one study physiological outcomes as evidence to support our conclusions. In the first experiment, we observed the adaptation of movement parameters such as pathlength, movement time, resultant velocity, and normalized jerk across groups trained with rotated visual feedback with both the left and right hands. Workspace location and hand differentially affected movement trajectory length. The group that practiced the task with their nondominant, left hand showed larger …

Structural Problems Of Latin American Cities 450 Years After Caracas’ Foundation, Fabio Capra-Ribeiro

Faculty Publications

Latin American cities face many problems that compromise them from different angles such as lack of infrastructure, government fragmentation, and environmental degradation. At the same time, each city tries to come up with its own solutions, but there are so many difficulties that in many cases it is difficult to keep attention and efforts focused on all these directions. For these reasons, this research aims to define some of the most common problems faced by cities in Latin America. Disseminating these similarities could help to face those problems, since, if local governments recognize that they face the same situations as …

The Spectra Of Hydrogen-Deficient Carbon Stars: The Effects Of Evolution And Nucleosynthesis, Courtney Lauren Crawford

LSU Doctoral Dissertations

The rare class of stars known as the Hydrogen-deficient Carbon (HdC) stars includes the R Coronae Borealis (RCB) variables and the non-variable Dustless HdC (dLHdC) stars. These stars are believed to be formed via the merger of two white dwarf (WD) stars. They are known to exhibit many spectral peculiarities, such as partial helium burning products, enhancement of s-processed material and severe hydrogen-deficiency. In this work I explore many facets of HdC evolution. I begin by creating 18 HdC models in the stellar evolution code Modules for Experiments in Stellar Astrophysics (MESA) by merging two WD progenitors and evolving the …

The Application Of Physics Informed Neural Networks To Compositional Modeling, Thelma A. Ihunde

LSU Master's Theses

Compositional modeling is essential when simulating processes involving significant changes in reservoir fluid composition. It is computationally expensive because we typically need to predict the states and properties of multicomponent fluid mixtures at several different points in space and time. To speed up this process, several researchers have used machine learning algorithms to train deep learning (DL) models on data from the rigorous phase-equilibrium (flash) calculations. However, one shortcoming of the DL models is that there is no explicit consideration for the governing physics. So, there is no guarantee that the model predictions will honor the thermodynamical constraints of phase …