Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

Louisiana State University

Discipline
Keyword
Publication Year
Publication
Publication Type
File Type

Articles 3571 - 3600 of 45175

Full-Text Articles in Entire DC Network

A Numerical Experiment Of Cold Front Induced Circulation In Wax Lake Delta: Evaluation Of Forcing Factors, Sajjad Feizabadi, Chunyan Li, Matthew Hiatt Jan 2023

A Numerical Experiment Of Cold Front Induced Circulation In Wax Lake Delta: Evaluation Of Forcing Factors, Sajjad Feizabadi, Chunyan Li, Matthew Hiatt

Faculty Publications

The effects of passing atmospheric cold fronts with different orientations and moving directions on the hydrodynamics of the Wax Lake Delta (WLD) were analyzed by considering the influence of river discharge, cold front moving direction, wind magnitude, and Coriolis effect. The study employs numerical simulations using the Delft-3D model and an analytical model to explore water volume transport, water level variations, water circulation, and particle trajectories during nine cold front events. Results indicate that cold fronts cause a decrease in the average contribution of the water transport through western channels and an increase of that in central and eastern channels. …

Go to article

Global Sea Surface Cyclogeostrophic Currents Derived From Satellite Altimetry Data, Yuhan Cao, Changming Dong, Alexandre Stegner, Brandon J. Bethel, Chunyan Li, Jihai Dong, L. Haibin, Jingsong Yang Jan 2023

Global Sea Surface Cyclogeostrophic Currents Derived From Satellite Altimetry Data, Yuhan Cao, Changming Dong, Alexandre Stegner, Brandon J. Bethel, Chunyan Li, Jihai Dong, L. Haibin, Jingsong Yang

Faculty Publications

Sea surface currents (SSC) derived from the sea surface height anomalies (SSHA) as measured by multi-satellite altimeters are widely used for various applications including studies on ocean dynamics, marine ecology, and climate change. However, present SSC products estimated on the assumption of an idealized geostrophic balance is biased. To overcome this idealization, this study considers flow curvature in the estimation of sea surface velocities in the global ocean, with the computation scheme validated using numerical model results. It is demonstrated that the inclusion of curvature into SSC estimations significantly changes SSC dynamic features in terms of kinetic energy, enstrophy (the …

Go to article

Design And Field-Scale Demonstration Of The Buoyant-Kill Process For Restoring Integrity Of Wells With Sustained Casing Pressure, Efecan Demirci, Andrew Wojtanowicz Jan 2023

Design And Field-Scale Demonstration Of The Buoyant-Kill Process For Restoring Integrity Of Wells With Sustained Casing Pressure, Efecan Demirci, Andrew Wojtanowicz

Faculty Publications

Sustained Casing Pressure (SCP) is the persistent casinghead pressure resulting from the well’s annular integrity loss and migration of gas above the leaking cement sheath. Downhole—intervention methods for SCP removal employ workover rigs to access and plug off the leaking annulus at depth from within the well. The inexpensive rig-less method of Buoyant Kill involves surface injection of immiscible heavy fluid at the casinghead into the well’s annulus to replace the annular fluid column above the gas-leaking cement and stop gas migration. Laboratory and pilot-size testing have shown feasibility of the method. Presented here, is a field-scale demonstration experiment conducted …

Go to article

Lighting Energy Load Prediction Framework Using Agent-Based Simulation And Artificial Neural Network Models, Sorena Vosoughkhosravi, Seddigheh Norouziasl, Amirhosein Jafari Jan 2023

Lighting Energy Load Prediction Framework Using Agent-Based Simulation And Artificial Neural Network Models, Sorena Vosoughkhosravi, Seddigheh Norouziasl, Amirhosein Jafari

Faculty Publications

Lighting is responsible for 17% of the total electricity consumption in commercial buildings in the United States. Investigating the lighting energy load provides the potential for more energy-saving in commercial buildings. Nonetheless, the development of lighting load prediction models has received limited attention in extant literature. This study proposes a framework to predict the lighting schedule and load in office buildings by integrating an agent-based model into an artificial neural network model. A small office building is used as a case study to simulate lighting load based on occupancy information using an agent-based model. Then, an artificial neural network model …

Go to article

Interrelationship-Based Information Delivery Manual Development For Smart City Infrastructure Systems, Moeid Shariatfar, Yong Cheol Lee, Ahmad Mohammad Ahmad, Salim Ferwati Jan 2023

Interrelationship-Based Information Delivery Manual Development For Smart City Infrastructure Systems, Moeid Shariatfar, Yong Cheol Lee, Ahmad Mohammad Ahmad, Salim Ferwati

Faculty Publications

Smart cities are comprised of various infrastructure systems interacting with heterogeneous context information that frequently causes critical challenges in data sharing, exchange, and integration of infrastructure components. The complicated structure of the infrastructure 3D models and the unraveled relationships of their functional, operational features remain elusive, hindering their seamless interactions. To ameliorate this issue, this paper proposes an interrelationship-based model view definition approach using an urban-level ontology that improves consistent data interoperability at the urban scale. The study includes the modularization of each infrastructure data conducted based on their functionalities and the development of an ontological structure for a smart …

Go to article

Floodsafehome: Evaluating Financial Benefits And Savings Of Freeboard For Improved Decision-Making In Flood Risk Mitigation, Carol J. Friedland, Yong Cheol Lee, Rubayet Bin Mostafiz, Jiyoung Lee, Shifat P. Mithila, Robert V. Rohli, Md Adilur Rahim, Ehab Gnan, Monica Teets Farris Jan 2023

Floodsafehome: Evaluating Financial Benefits And Savings Of Freeboard For Improved Decision-Making In Flood Risk Mitigation, Carol J. Friedland, Yong Cheol Lee, Rubayet Bin Mostafiz, Jiyoung Lee, Shifat P. Mithila, Robert V. Rohli, Md Adilur Rahim, Ehab Gnan, Monica Teets Farris

Faculty Publications

Freeboard—elevation of a structure above the base flood elevation (BFE)—is a critical component in mitigating or avoiding flood losses. However, the unrevealed benefits and savings of freeboard installation have prevented communities from adopting this approach. To improve decision-making for residents, prospective residents, and other stakeholders in flood-vulnerable communities and enhance flood risk mitigation strategies, this study presents the methodology underlying a new webtool, FloodSafeHome, that estimates comprehensively the economic benefits and savings of freeboard installation for new construction of residential buildings. Specifically, the proposed evaluation framework has been designed to calculate monthly savings for individual buildings by assessing freeboard cost, …

Go to article

Ontology For Experimentation Of Human-Building Interactions Using Virtual Reality, Chanachok Chokwitthaya, Yimin Zhu, Weizhuo Lu Jan 2023

Ontology For Experimentation Of Human-Building Interactions Using Virtual Reality, Chanachok Chokwitthaya, Yimin Zhu, Weizhuo Lu

Faculty Publications

Scientific experiments significantly enhance the understanding of human-building interactions in building and engineering research. Recently, conducting virtual reality (VR) experiments has gained acceptance and popularity as an approach to studying human-building interactions. However, little attention has been given to the standardization of the experimentations. Proper standardization can promote the reusability, replicability, and repeatability of VR experiments and accelerate the maturity of this emerging experimentation method. Responding to such needs, the authors proposed a virtual human-building interaction experimentation ontology (VHBIEO). It is an ontology at the domain level, extending the ontology of scientific experiments (EXPO) to standardize virtual human-building interaction experimentation. …

Go to article

Visual Literacy Unframed: Planning An Oer To Improve College-Level Visual Analysis Skills, Marty Miller Jan 2023

Visual Literacy Unframed: Planning An Oer To Improve College-Level Visual Analysis Skills, Marty Miller

Faculty Publications

No abstract provided.

Go to article

A Community-Engaged Oral History Study As A Tool For Understanding Environmental Justice Aspects Of Human Exposures To Hazardous Waste Thermal Treatment Emissions In Colfax, La, Matilda Odera, Blair Kelley, Louie Rivers, Alyanna Wilson, Jessica Tran, Khushi Patel, Brenda Vallee, Wilma Subra, Jennifer A. Cramer, Jennifer K. Irving, Margaret Reams, Jennifer Richmond-Bryant Jan 2023

A Community-Engaged Oral History Study As A Tool For Understanding Environmental Justice Aspects Of Human Exposures To Hazardous Waste Thermal Treatment Emissions In Colfax, La, Matilda Odera, Blair Kelley, Louie Rivers, Alyanna Wilson, Jessica Tran, Khushi Patel, Brenda Vallee, Wilma Subra, Jennifer A. Cramer, Jennifer K. Irving, Margaret Reams, Jennifer Richmond-Bryant

Faculty Publications

This study investigates environmental justice (EJ) themes related to siting a hazardous waste thermal treatment facility near a low-income community of color. We investigated effects of living near a hazardous waste thermal treatment facility through three EJ aspects: recognitional, procedural, and distributive justice. The study involved the collection of oral history interviews from residents of Colfax, a town in Grant Parish, Louisiana, that hosts an open burn/open detonation hazardous waste thermal treatment facility. The facility processes materials such as munitions, theme park waste, and contaminated soils from Superfund sites, and it increased its volume drastically in 2014. Residents reported adverse …

Go to article

Poems On Gender, Sexuality, And Kinship, Elisa Subin Jan 2023

Poems On Gender, Sexuality, And Kinship, Elisa Subin

Comparative Woman

The attached poems are a series thematically linked through gender, sexuality, and kinship.

Go to article

Recent Insights Into The Molecular Mechanisms Of Simultaneous Fatty Acid Oxidation And Synthesis In Brown Adipocytes, Ji Suk Chang Jan 2023

Recent Insights Into The Molecular Mechanisms Of Simultaneous Fatty Acid Oxidation And Synthesis In Brown Adipocytes, Ji Suk Chang

Division of Basic Science Faculty Publications

Brown adipocytes is a specialized fat cell that dissipates nutrient-derived chemical energy in the form of heat, instead of ATP synthesis. This unique feature provides a marked capacity for brown adipocyte mitochondria to oxidize substrates independent of ADP availability. Upon cold exposure, brown adipocytes preferentially oxidize free fatty acids (FFA) liberated from triacylglycerol (TAG) in lipid droplets to support thermogenesis. In addition, brown adipocytes take up large amounts of circulating glucose, concurrently increasing glycolysis and de novo FA synthesis from glucose. Given that FA oxidation and glucose-derived FA synthesis are two antagonistic mitochondrial processes in the same cell, it has …

Go to article

Exercise Training, Cardiac Biomarkers, And Cardiorespiratory Fitness In Type 2 Diabetes: The Hart-D Study, Kershaw V. Patel, Amit Saha, Colby R. Ayers, Anand Rohatgi, Jarett D. Berry, Jaime P. Almandoz, Neil M. Johannsen, Christopher Defilippi, Timothy S. Church, James A. De Lemos, Ambarish Pandey Jan 2023

Exercise Training, Cardiac Biomarkers, And Cardiorespiratory Fitness In Type 2 Diabetes: The Hart-D Study, Kershaw V. Patel, Amit Saha, Colby R. Ayers, Anand Rohatgi, Jarett D. Berry, Jaime P. Almandoz, Neil M. Johannsen, Christopher Defilippi, Timothy S. Church, James A. De Lemos, Ambarish Pandey

Clinical Research Faculty Publications

Background: High-sensitivity cardiac troponin T (hs-cTnT) and N-terminal pro-B-type natriuretic peptide (NT-proBNP) are cardiac biomarkers commonly detected in adults with type 2 diabetes (T2D) and are associated with heart failure risk. Objectives: The purpose of this study was to evaluate the effects of exercise training (ET) on hs-cTnT and NT-proBNP and evaluate the associations of these biomarkers with cardiorespiratory fitness among adults with T2D. Methods: Participants of the HART-D (Health Benefits of Aerobic and Resistance Training in Individuals with Type 2 Diabetes) trial who were randomly assigned to one of 3 ET groups or a non-exercise control group were included. …

Go to article

The Role Of Fmri In Drug Development: An Update, Owen Carmichael Jan 2023

The Role Of Fmri In Drug Development: An Update, Owen Carmichael

Clinical Research Faculty Publications

Functional magnetic resonance imaging (fMRI) of the brain is a technology that holds great potential for increasing the efficiency of drug development for the central nervous system (CNS). In preclinical studies and both early- and late-phase human trials, fMRI has the potential to improve cross-species translation of drug effects, help to de-risk compounds early in development, and contribute to the portfolio of evidence for a compound’s efficacy and mechanism of action. However, to date, the utilization of fMRI in the CNS drug development process has been limited. The purpose of this chapter is to explore this mismatch between potential and …

Go to article

Aberrant Lipid Accumulation In The Mouse Visceral Yolk Sac Resulting From Maternal Diabetes And Obesity, Man Zhang, J. Michael Salbaum, Sydney Jones, David Burk, Claudia Kappen Jan 2023

Aberrant Lipid Accumulation In The Mouse Visceral Yolk Sac Resulting From Maternal Diabetes And Obesity, Man Zhang, J. Michael Salbaum, Sydney Jones, David Burk, Claudia Kappen

Division of Basic Science Faculty Publications

Maternal diabetes and obesity in pregnancy are well-known risk factors for structural birth defects, including neural tube defects and congenital heart defects. Progeny from affected pregnancies are also predisposed to developing cardiometabolic disease in later life. Based upon in vitro embryo cultures of rat embryos, it was postulated that nutrient uptake by the yolk sac is deficient in diabetic pregnancies. In contrast, using two independent mouse models of maternal diabetes, and a high-fat diet-feeding model of maternal obesity, we observed excessive lipid accumulation at 8.5 days in the yolk sac. The numbers as well as sizes of intracellular lipid droplets …

Go to article

Factors Influencing Nutritional Intake And Interests In Educational Content Of Athletes And Sport Professionals Toward The Development Of A Clinician-Supported Mobile App To Combat Relative Energy Deficiency In Sport: Formative Research And A Description Of App Functions, Jacob T. Mey, Christine A. Karpinski, Shengping Yang, Joseph D. Madere, Tavis Piattoly, Ronnie Harper, John P. Kirwan Jan 2023

Factors Influencing Nutritional Intake And Interests In Educational Content Of Athletes And Sport Professionals Toward The Development Of A Clinician-Supported Mobile App To Combat Relative Energy Deficiency In Sport: Formative Research And A Description Of App Functions, Jacob T. Mey, Christine A. Karpinski, Shengping Yang, Joseph D. Madere, Tavis Piattoly, Ronnie Harper, John P. Kirwan

Division of Basic Science Faculty Publications

Background: Relative energy deficiency in sport (RED-S) as a consequence of athlete malnutrition remains a prominent issue. However, it remains underrecognized, in part due to the perceived outward health of athletes. The Eat2Win app was designed to combat RED-S and athlete malnutrition by providing education, behavior modification, and direct communication with expert sports dietitians to athletes and sport professionals (professionals who work with athletes, eg, sport coaches and athletic trainers). Objective: The purpose of this formative research was to gain critical insight on motivators and barriers to optimal nutritional intake from both the athletes’ and sport professionals’ perspectives. Additionally, since …

Go to article

Joint Estimation Of Neural Events And Hemodynamic Response Functions From Task Fmri Via Convolutional Neural Networks, Kai Cheng Chuang, Sreekrishna Ramakrishnapillai, Krystal Kirby, Arend W.A. Van Gemmert, Lydia Bazzano, Owen T. Carmichael Jan 2023

Joint Estimation Of Neural Events And Hemodynamic Response Functions From Task Fmri Via Convolutional Neural Networks, Kai Cheng Chuang, Sreekrishna Ramakrishnapillai, Krystal Kirby, Arend W.A. Van Gemmert, Lydia Bazzano, Owen T. Carmichael

Clinical Research Faculty Publications

Joint decomposition of functional magnetic resonance imaging (fMRI) time series into time courses of neural activity events and hemodynamic response functions (HRF) can enable new insights into functional connectivity, task activation, and neurovascular coupling in health and disease. Current methods for this problem handle time series of either temporally isolated events or extended blocks of continuous events but not both; and they constrain the HRF to one specific functional form. We propose to use an autoencoder and a convolutional neural network (CNN) to overcome these challenges. The autoencoder uses convolutional neural networks to reconstruct the fMRI time series while estimating …

Go to article

S.W. Griffith: A Suitable Case For Indictment?, Mark Finnane, Jonathan Richards Jan 2023

S.W. Griffith: A Suitable Case For Indictment?, Mark Finnane, Jonathan Richards

Faculty Publications

In his 2021 book ‘Truth-Telling: History, Sovereignty and the Uluru Statement’, Henry Reynolds called for an inquiry into the historical record of Samuel Walker Griffith, Federation ‘father’ and first Chief Justice of the High Court of Australia. Reynolds’ iconoclasm targeted a historical figure whose name is memorialised in a Riverina town, a Canberra suburb and a Queensland university. Reynolds charged that Griffith was morally and politically responsible for the violence carried out by an agency of the Queensland government, the Native Police. This historically grounded allegation relates to Griffith's pre-Federation Queensland political career, 1874–93, when he served intermittently as Premier, …

Go to article

Evaluation Of Fumigant And Non-Fumigant Nematicides For Management Of Rotylenchulus Reniformis On Sweetpotato, Tristan T. Watson, Caleb S. Hamm, J. Cole Gregorie Jan 2023

Evaluation Of Fumigant And Non-Fumigant Nematicides For Management Of Rotylenchulus Reniformis On Sweetpotato, Tristan T. Watson, Caleb S. Hamm, J. Cole Gregorie

Faculty Publications

Reniform nematode (Rotylenchulus reniformis) is a major pest of sweetpotato in many production regions in Southern United States. Applying soil fumigants and non-fumigant nematicides are the primary management strategies available to growers. This study compared the relative efficacy of nematicides (1,3-dichloropropene, fluopyram, oxamyl, fluazaindolizine, aldicarb, Majestene, and fluensulfone) for management of reniform nematode on sweetpotato. Fumigating soil with 1,3-dichloropropene consistently reduced soil population densities of reniform nematode at the time of planting in both trial years (31 - 36% reduction relative to the untreated control); however, the duration of suppression varied greatly by growing season. A similar trend was observed …

Go to article

Factors That Predict Weight Loss Success Differ By Diet Intervention Type, Jordan Losavio, Michael J. Keenan, Elizabeth A. Gollub, Heidi J. Silver Jan 2023

Factors That Predict Weight Loss Success Differ By Diet Intervention Type, Jordan Losavio, Michael J. Keenan, Elizabeth A. Gollub, Heidi J. Silver

Faculty Publications

Background: Many types of diet intervention can achieve negative energy balance and successful weight loss in persons with obesity. However, within any dietary strategy, there is large inter-individual variation in the weight loss response. The aim of this study is to determine factors that predict weight loss success for diet interventions that vary by macronutrient and caloric composition. Methods: Participants with BMI 30.0 to 49.9 kg/m2 self-selected one of three diet intervention trials for weight loss: low carbohydrate (LOW CHO), low fat (LOW FAT), or low calorie (LOW KCAL). Multivariable regression models were developed to determine the significance of predictor …

Go to article

Comparative Genomics Of The Niche-Specific Plant Pathogen Streptomyces Ipomoeae Reveal Novel Genome Content And Organization, Natasha R. Soares, José C. Huguet-Tapia, Dongli Guan, Christopher A. Clark, Kuei Ting Yang, Olivia R. Kluchka, Raju S. Thombal, Rendy Kartika, Jonathan H. Badger, Gregg S. Pettis Jan 2023

Comparative Genomics Of The Niche-Specific Plant Pathogen Streptomyces Ipomoeae Reveal Novel Genome Content And Organization, Natasha R. Soares, José C. Huguet-Tapia, Dongli Guan, Christopher A. Clark, Kuei Ting Yang, Olivia R. Kluchka, Raju S. Thombal, Rendy Kartika, Jonathan H. Badger, Gregg S. Pettis

Faculty Publications

The sweet potato soil rot pathogen Streptomyces ipomoeae differs in disease pathology, host range, and virulence factor production from Streptomyces species that cause scab diseases on potato and other plant hosts. Nevertheless, previous phylogenomic analysis suggested S. ipomoeae and the oldest scab species, Streptomyces scabiei, are derived from a common ancestor. While genomes of scab pathogens have been described in some detail, similar knowledge of S. ipomoeae has been lacking. Here, we performed comparative genomic analyses involving both virulent and avirulent strains of S. ipomoeae, along with other plant-pathogenic and saprophytic Streptomyces spp. The txt gene cluster for the phytotoxin …

Go to article

Ophiclypeus, A New Genus Of Cardiochilinae Ashmead (Hymenoptera, Braconidae) From The Oriental Region With Descriptions Of Three New Species, Ilgoo Kang, Mostafa Ghafouri Moghaddam, Michael J. Sharkey, Donald L.J. Quicke, Buntika A. Butcher, Christopher E. Carlton Jan 2023

Ophiclypeus, A New Genus Of Cardiochilinae Ashmead (Hymenoptera, Braconidae) From The Oriental Region With Descriptions Of Three New Species, Ilgoo Kang, Mostafa Ghafouri Moghaddam, Michael J. Sharkey, Donald L.J. Quicke, Buntika A. Butcher, Christopher E. Carlton

Faculty Publications

A new genus of the braconid subfamily Cardiochilinae, Ophiclypeus gen. nov., is described and illustrated based on three new species: O. chiangmaiensis Kang, sp. nov. type species (type locality: Chiang Mai, Thailand), O. dvaravati Ghafouri Moghaddam, Quicke & Butcher, sp. nov. (type locality: Saraburi, Thailand), and O. junyani Kang, sp. nov. (type locality: Dalin, Taiwan). We provide morphological diagnostic characters to separate the new genus from other cardiochiline genera. A modified key couplet (couplet 5) and a new key couplet (couplet 16) are provided with detailed imag-es for Dangerfield’s key to the world cardiochiline genera to facilitate recognition of Ophiclypeus …

Go to article

Effect Of Storage Temperature And Produce Type On The Survival Or Growth Of Listeria Monocytogenes On Peeled Rinds And Fresh-Cut Produce, Juan Moreira, Erika Mera, Vijay Singh Chhetri, Joan M. King, Thanos Gentimis, Achyut Adhikari Jan 2023

Effect Of Storage Temperature And Produce Type On The Survival Or Growth Of Listeria Monocytogenes On Peeled Rinds And Fresh-Cut Produce, Juan Moreira, Erika Mera, Vijay Singh Chhetri, Joan M. King, Thanos Gentimis, Achyut Adhikari

Faculty Publications

Whole and fresh-cut produce are minimally processed and susceptible to microbial contamination. This study evaluated the survival or growth of L. monocytogenes on peeled rinds, and fresh-cut produce at different storage temperatures. Fresh-cut fruits and vegetables, including cantaloupe, watermelon, pear, papaya, pineapple, broccoli, cauliflower, lettuce, bell pepper, and kale (25 g pieces) were spot inoculated with 4 log CFU/g of L. monocytogenes and stored at 4 or 13°C for 6 days. Cantaloupe and bell pepper rind disks (20 cm2), mimicking whole produce were inoculated with low inoculum level (4 log CFU/mL) and high inoculum level (6 log CFU/mL) and stored …

Go to article

Challenges In The Combination Of Radiotherapy And Immunotherapy For Breast Cancer, Rui Zhang, Samantha D. Clark, Beibei Guo, Tianyi Zhang, Duane Jeansonne, Samithamby J. Jeyaseelan, Joseph Francis, Weishan Huang Jan 2023

Challenges In The Combination Of Radiotherapy And Immunotherapy For Breast Cancer, Rui Zhang, Samantha D. Clark, Beibei Guo, Tianyi Zhang, Duane Jeansonne, Samithamby J. Jeyaseelan, Joseph Francis, Weishan Huang

Faculty Publications

Introduction: Immunotherapy (IT) is showing promise in the treatment of breast cancer, but IT alone only benefits a minority of patients. Radiotherapy (RT) is usually included in the standard of care for breast cancer patients and is traditionally considered as a local form of treatment. The emerging knowledge of RT-induced systemic immune response, and the observation that the rare abscopal effect of RT on distant cancer metastases can be augmented by IT, have increased the enthusiasm for combinatorial immunoradiotherapy (IRT) for breast cancer patients. However, IRT largely follows the traditional sole RT and IT protocols and does not consider patient …

Go to article

A Bayesian Phase I/Ii Design To Determine Subgroup-Specific Optimal Dose For Immunotherapy Sequentially Combined With Radiotherapy, Beibei Guo, Yong Zang, Li Hsiang Lin, Rui Zhang Jan 2023

A Bayesian Phase I/Ii Design To Determine Subgroup-Specific Optimal Dose For Immunotherapy Sequentially Combined With Radiotherapy, Beibei Guo, Yong Zang, Li Hsiang Lin, Rui Zhang

Faculty Publications

Sequential administration of immunotherapy following radiotherapy (immunoRT) has attracted much attention in cancer research. Due to its unique feature that radiotherapy upregulates the expression of a predictive biomarker for immunotherapy, novel clinical trial designs are needed for immunoRT to identify patient subgroups and the optimal dose for each subgroup. In this article, we propose a Bayesian phase I/II design for immunotherapy administered after standard-dose radiotherapy for this purpose. We construct a latent subgroup membership variable and model it as a function of the baseline and pre-post radiotherapy change in the predictive biomarker measurements. Conditional on the latent subgroup membership of …

Go to article

“Knowing Which Way The Wind Was Blowing During Reconstruction”, Hans Rasmussen Jan 2023

“Knowing Which Way The Wind Was Blowing During Reconstruction”, Hans Rasmussen

Civil War Book Review

The events of Reconstruction played out within the context of an agrarian society where most people lived in rural areas, close to nature and susceptible to the fickle whims of weather and climate. A dry summer, a wet spring, a sudden flood, or an early killing frost may have put a locality’s agricultural economy out of joint for a while and spun off other political or social reverberations. Understanding how these various political, economic, social, and climactic factors played off each other to produce the volatile events of the Reconstruction era will present a challenging puzzle for historians to unravel. …

Go to article

Horse Soldiers At Gettysburg: The Cavalryman’S View Of The Civil War’S Pivotal Campaign, Allen C. Guelzo Jan 2023

Horse Soldiers At Gettysburg: The Cavalryman’S View Of The Civil War’S Pivotal Campaign, Allen C. Guelzo

Civil War Book Review

Daniel Murphey's Horse Soldiers at Gettysburg: The Cavalryman’s View of the Civil War’s Pivotal Campaign brings to his account a lively appreciation for the character of horses and their high-maintenance demands. He adds to that another virtue, that of not being obsessed with J.E.B. Stuart, so that both Federal and Confederate cavalry get remarkably equal billing. For those interested in cavalry operations during the Gettysburg campaign, this book stands as a fine introduction to the cavalry’s campaign at Gettysburg, and well-illustrated.

Go to article

2023 Annual Report, Louisiana Rice Research Board, Lsu Agcenter Jan 2023

2023 Annual Report, Louisiana Rice Research Board, Lsu Agcenter

Louisiana Rice Research Board Annual Report

No abstract provided.

Go to article

Impact Report, 2022-2023, Lsu Libraries Jan 2023

Impact Report, 2022-2023, Lsu Libraries

Libraries Impact Reports

No abstract provided.

Go to article

A Man Of Bad Reputation: The Murder Of John Stephens And The Contested Landscape Of North Carolina Reconstruction, Evan Rothera Jan 2023

A Man Of Bad Reputation: The Murder Of John Stephens And The Contested Landscape Of North Carolina Reconstruction, Evan Rothera

Civil War Book Review

A Man of Bad Reputation opens with John G. Lea’s confession that he had assassinated North Carolina State Senator John Walter Stephens in 1870. Lea gave his confession in 1919, nearly half a century after the murder. Stephens’s death, Drew A. Swanson contends, had profound repercussions. On the one hand, it “featured prominently in the US Congress’s investigation of Klan activities in the South,” which eventually led for the Enforcements Acts and the end of the first Ku Klux Klan. On the other hand, it sparked the Kirk-Holden War, which led to the impeachment of Governor William Woods Holden, his …

Go to article

Targeting The Aspergillus Flavus P2c Gene Through Host-Induced Gene Silencing Reduces A. Flavus Infection And Aflatoxin Contamination In Transgenic Maize, Yenjit Raruang, Olanike Omolehin, Dongfang Hu, Qijian Wei, Surassawadee Promyou, Lidiya J. Parekattil, Kanniah Rajasekaran, Jeffrey W. Cary, Kan Wang, Zhi Yuan Chen Jan 2023

Targeting The Aspergillus Flavus P2c Gene Through Host-Induced Gene Silencing Reduces A. Flavus Infection And Aflatoxin Contamination In Transgenic Maize, Yenjit Raruang, Olanike Omolehin, Dongfang Hu, Qijian Wei, Surassawadee Promyou, Lidiya J. Parekattil, Kanniah Rajasekaran, Jeffrey W. Cary, Kan Wang, Zhi Yuan Chen

Faculty Publications

Aspergillus flavus is an opportunistic fungal pathogen that infects maize and produces aflatoxins. Using biocontrol or developing resistant cultivars to reduce aflatoxin contamination has only achieved limited success. Here, the A. flavus polygalacturonase gene (p2c) was targeted for suppression through host-induced gene silencing (HIGS) to reduce aflatoxin contamination in maize. An RNAi vector carrying a portion of the p2c gene was constructed and transformed into maize B104. Thirteen out of fifteen independent transformation events were confirmed to contain p2c. The T2 generation kernels containing the p2c transgene had less aflatoxin than those without the transgene in six out of eleven …

Go to article

First Prev Next Last