Digital Commons Network^™

Nano-Injection Molding With Resin Mold Inserts For Prototyping Of Nanofluidic Devices For Single Molecular Detection, Farhad Shiri, Junseo Choi, Chad Vietz, Chathurika Rathnayaka, Anishkumar Manoharan, Suresh Shivanka, Guoqiang Li, Chengbin Yu, Michael C. Murphy, Steven A. Soper, Sunggook Park

Faculty Publications

While injection molding is becoming the fabrication modality of choice for high-scale production of microfluidic devices, especially those used for in vitro diagnostics, its translation into the growing area of nanofluidics (structures with at least one dimension <100 >nm) has not been well established. Another prevailing issue with injection molding is the high startup costs and the relatively long time between device iterations making it in many cases impractical for device prototyping. We report, for the first time, functional nanofluidic devices with dimensions of critical structures below 30 nm fabricated by injection molding for the manipulation, identification, and detection of single …

Are We There Yet?, Marion S. Freistadt

LSU Master's Theses

To solve the Climate Crisis, a global Energy Transition is required. The primary contemporary tool for tackling these two massive problems is modeling, both biophysical climate models and IAMS (Integrated Assessment Models) which combine socioeconomic and technological progress with Climate Change. However, the proliferation and complexity of modeling systems make it difficult for most people to contribute substantively to solutions. In particular, stakeholders, policymakers, nonspecialists and activists require sufficient understanding of modeling to impact outcomes.

In this thesis, after summarizing the Climate Crisis and potential Energy Transition solutions, I review current modeling approaches. Models can be considered in terms of …

Unveiling Indicator, Enteric, And Respiratory Viruses In Aircraft Lavatory Wastewater Using Adsorption-Extraction And Nanotrap® Microbiome A Particles Workflows, Warish Ahmed, Wendy J.M. Smith, Ananda Tiwari, Aaron Bivins, Stuart L. Simpson

Faculty Publications

The effective detection of viruses in aircraft wastewater is crucial to establish surveillance programs for monitoring virus spread via aircraft passengers. This study aimed to compare the performance of two virus concentration workflows, adsorption-extraction (AE) and Nanotrap® Microbiome A Particles (NMAP), in detecting the prevalence and concentrations of 15 endogenous viruses including ssDNA, dsDNA, ssRNA in 24 aircraft lavatory wastewater samples. The viruses tested included two indicator viruses, four enteric viruses, and nine respiratory viruses. The results showed that cross-assembly phage (crAssphage), human polyomavirus (HPyV), rhinovirus A (RhV A), and rhinovirus B (RhV B) were detected in all wastewater samples …

Secondary Traumatic Stress And Other Contributors To Teacher Burnout And Attrition, Mary Snellings W. Inabnett

LSU Master's Theses

Teachers are the most important factor in eliciting positive student outcomes. Yet, teacher attrition is an increasing problem, due to the demands of the profession. These demands are exacerbated in high-needs schools, which serve students who are exposed to higher levels of stress and trauma. It is understood that, because of the populations high-needs schools serve, teachers who work in these schools are exposed to secondary traumatic stress (STS) at higher rates than other teachers. What is less clear is if STS exposure contributes to teacher attrition, beyond other known factors. The current study surveyed 104 teachers from a school …

Building Solidarity Between Minority Groups, Seonwoo Kim

LSU Doctoral Dissertations

Although a considerable number of scholars agree that an intergroup coalition among minorities will be more powerful in changing biased perceptions, regulations, and policies (e.g., Burson & Godfrey, 2020; Lane et al., 2019), cross-minority solidarity is challenging due to the inherent difficulties in establishing a shared goal and reaching a consensus on methods and tactics (Gawerc, 2021; Rogers, 2004) and competing policy stances and stereotypes (Hope, 2019; Nopper, 2006). Numerous instances of social movements that failed due to the failure of coalitions to form have been documented in the literature (e.g., Almeida, 2010; Ferree & Roth, 1998; Gelb & Shogan, …

Deciphering The Role Of Molecular Interactions On The Interfacial Structure Of Aqueous And Non-Aqueous Interfaces, Dodangodage Ishara Indunil Senadheera, D I. Senadheera

LSU Doctoral Dissertations

The study focused on "Deciphering the role of molecular interactions on the interfacial structure of aqueous and non-aqueous interfaces" holds immense significance in diverse scientific and industrial domains. Our primary objective is to unravel the intricate web of molecular interactions occurring at the boundaries between aqueous and non-aqueous phases. The research presented here spans a wide scope, encompassing applications in microelectromechanical systems in the semiconductor industry, energy-efficient membranes for electrochemical separations, and renewable energy storage systems. Molecular dynamics simulations were conducted in collaboration with experimental studies, specifically atomic force microscopy, to achieve insights at the molecular level.The first project centered …

Rangewide Migratory Connectivity And Migration Ecology In Swainson's Warblers (Limnothlypis Swainsonii) Derived From Multisensor Geolocators, Garrett Rhyne

LSU Master's Theses

Successful conservation of Neotropical migratory passerines requires a detailed understanding of their annual cycle ecology, including wintering and breeding distributions, migratory pathways and stopovers, and migratory phenology. It is also important to evaluate the extent of geographic isolation between separate breeding populations during the nonbreeding season, known as migratory connectivity. Swainson’s Warbler (Limnothlypis swainsonii) is a species of conservation concern that, due to their secretive nature and selection of dense forest habitats, is poorly studied and lacks migratory information. Our objective was to track Swainson’s Warblers across their breeding populations (Mississippi Valley, Coastal Plains, and Appalachian) to detail …

Nostalgic Reaction In Narratives Of Lost Memories In Negar Djavadi’S Désorientale, Zahra Vodjgani

Tête à Tête: Journal of Francophone Studies

No abstract provided.

A Metropolitan French Isolate In North America: The French Language In Saint-Pierre-Et-Miquelon, Marc Cormier

Tête à Tête: Journal of Francophone Studies

No abstract provided.

France Within Louisiana Law, Government, And Media, Nicolas Garon

Tête à Tête: Journal of Francophone Studies

No abstract provided.

Le Québec Entre Le « Past-Self » Et Le « Possible-Self » Dans La Face Cachée De La Lune, Andisheh Ghaderi

Tête à Tête: Journal of Francophone Studies

No abstract provided.

Tumultuous Devotions: Female Entrapment & Empowerment In The Lais Of Marie De France, Trent Dunkin

Tête à Tête: Journal of Francophone Studies

No abstract provided.

Entre Ombre Et Lumière : L’Artifice Et La Réflexion Sociétale Dans La Princesse Maleine De Maeterlinck, Anoosheh Ghaderi

Tête à Tête: Journal of Francophone Studies

No abstract provided.

Lrtransformer: Learn-Region Transformer For Object-Agnostic Point Cloud Segmentation, Dipesh Gyawali

LSU Master's Theses

3D point cloud segmentation segments the 3D point cloud data into different regions/instances depending on their features that have numerous applications in robotics, autonomous driving, digital twinning, augmented reality, etc. The majority of the existing point cloud segmentation methods depend on class labels to identify 3D objects in the surroundings. Our work focuses on segmenting point clouds into different regions/instances in an object-agnostic manner for any number of objects in the environment. Given the point cloud, our method can segment the entire scene into multiple instances without depending on object shape and size. We leverage the power of the self-attention …

Cationic Frontal Polymerization: Front Kinetics, Effects Of Additives, And Applications, Brecklyn R. Groce

LSU Doctoral Dissertations

Cationic frontal polymerization broadens the potential application of frontal polymerization by allowing for use of monomers such as epoxies and vinyl ethers. In this work, the effects of monomer and initiator composition and additives including fillers on front kinetics, along with applications of cationic frontal polymerization were investigated.

Using a radical-induced cationic frontal polymerization (RICFP) method with a superacid generating salt and a thermal radical initiator, the addition of vinyl ethers to epoxy formulations was studied, where an increase of front velocity was seen with increase of divinyl ether to epoxy ratio. Other aspects of vinyl ether systems, such as …

High Performance And Recyclable Thermoset Ink For 3d Or 4d Printing, Ang Li, Guoqiang Li

College of Engineering Patents

A UV-curable and recyclable thermoset shape memory polymer is provided. The polymer includes a vitrimer-based monomer and a photoinitiator. The vitrimer-based monomer includes a first unit rendering a high chain stiffness upon polymerization of the monomer, and a second photopolymerizable unit for photopolymerization of the monomer under a UV irradiation. The polymer has high strength, high stiffness, high recovery stress, high energy storage, reasonable recycling efficiency, and is printable using SLA with high resolution.

Deconvoluting Charge-Transfer, Mass Transfer, And Ohmic Resistances In Phosphonic Acid-Sulfonic Acid Ionomer Binders Used In Electrochemical Hydrogen Pumps, Karthik Arunagiri, Andrew Jark Wah Wong, Luis Briceno-Mena, Hania Mohamed Gaber Hassan Elsayed, José A. Romagnoli, Michael J. Janik, Christopher G. Arges

Faculty Publications

Ion-pair high-temperature polymer electrolyte membranes (HT-PEMs) paired with phosphonic acid ionomer electrode binders have substantially improved the performance of HT-PEM electrochemical hydrogen pumps (EHPs) and fuel cells. Blending poly(pentafluorstyrene-co-tetrafluorostyrene phosphonic acid) (PTFSPA) with Nafion™, and using this blend as an electrode binder, improved proton conductivity in the electrode layer resulting in a 2 W cm−2 peak power density of fuel cells at 240 °C (a HT-PEM fuel cell record). However, much is unknown about how phosphonic acid ionomers blended with perfluorosulfonic acid materials affect electrode kinetics and gas transport in porous electrodes. In this work, we studied the proton conductivity, …

How Ubiquitous Is Entanglement In Quantum Field Theory, Ivan Agullo, Béatrice Bonga, Patricia Ribes-Metidieri, Dimitrios Kranas, Sergi Nadal-Gisbert

Faculty Publications

It is well known that entanglement is widespread in quantum field theory, in the following sense: every Reeh-Schlieder state contains entanglement between any two spatially separated regions. This applies, in particular, to the vacuum of a noninteracting scalar theory in Minkowski spacetime. Discussions on entanglement in field theory have focused mainly on subsystems containing infinitely many degrees of freedom - typically, the field modes that are supported within a compact region of space. In this article, we study entanglement in subsystems made of finitely many field degrees of freedom, in a free scalar theory in D+1-dimensional Minkowski spacetime. The focus …

Ready Worker One? High-Res Vr For The Home Office, Anastasia Ruvimova, Felipe Fronchetti, Boden A. Kahn, Luiz Henrique Susin, Zekeya Hurley, Thomas Fritz, Mark Hancock, David Shepherd

Faculty Publications

Many employees prefer to work from home, yet struggle to squeeze their office into an already fully-utilized space. Virtual Reality (VR) seemingly offered a solution with its ability to transform even modest physical spaces into spacious, productive virtual offices, but hardware challenges - such as low resolution - have prevented this from becoming a reality. Now that hardware issues are being overcome, we are able to investigate the suitability of VR for daily work. To do so, we (1) studied the physical space that users typically dedicate to home offices and (2) conducted an exploratory study of users working in …

Influences On Participation In The National Flood Insurance Program’S Community Rating System In Coastal Counties In Louisiana, Mississippi, Alabama, And Florida, Jennifer E. Argote

LSU Doctoral Dissertations

The National Flood Insurance Program provides an incentive-based program, the Community Rating System (“CRS”), to encourage communities to improve their hazard mitigation protocols to better protect against and prevent flood-related hazards. This dissertation analyzes factors that influence participation and points scored within the CRS to gain an understanding of the conditions under which communities are willing and able to take advantage of an incentive-based flood hazard mitigation program. It also includes an analysis of survey responses from 41 coastal county floodplain and CRS managers to gauge their opinions on the CRS and how it can be improved to better serve …

Continuous Spin Excitations In The Three-Dimensional Frustrated Magnet K2ni2 (So4)3, Weiliang Yao, Qing Huang, Tao Xie, Andrey Podlesnyak, Alexander Brassington, Chengkun Xing, Ranuri S.Dissanayaka Mudiyanselage, Haozhe Wang, Weiwei Xie, Shengzhi Zhang, Minseong Lee, Vivien S. Zapf, Xiaojian Bai, D. Alan Tennant, Jian Liu, Haidong Zhou

Faculty Publications

Continuous spin excitations are widely recognized as one of the hallmarks of novel spin states in quantum magnets, such as quantum spin liquids (QSLs). Here, we report the observation of such kind of excitations in K2Ni2(SO4)3, which consists of two sets of intersected spin-1 (Ni2+) trillium lattices. Our inelastic neutron scattering measurement on single crystals clearly shows a dominant excitation continuum, which exhibits a distinct temperature-dependent behavior from that of spin waves, and is rooted in strong quantum spin fluctuations. Further using the self-consistent-Gaussian-approximation method, we determine that the fourth- and fifth-nearest-neighbor exchange interactions are dominant. These two bonds together …

Role Of Domain-Domain Interactions On The Self-Association And Physical Stability Of Monoclonal Antibodies: Effect Of Ph And Salt, Amy Y. Xu, Marco A. Blanco, Maria Monica Castellanos, Curtis W. Meuse, Kevin Mattison, Ioannis Karageorgos, Harold W. Hatch, Vincent K. Shen, Joseph E. Curtis

Faculty Publications

Monoclonal antibodies (mAbs) make up a major class of biotherapeutics with a wide range of clinical applications. Their physical stability can be affected by various environmental factors. For instance, an acidic pH can be encountered during different stages of the mAb manufacturing process, including purification and storage. Therefore, understanding the behavior of flexible mAb molecules in acidic solution environments will benefit the development of stable mAb products. This study used small-angle X-ray scattering (SAXS) and complementary biophysical characterization techniques to investigate the conformational flexibility and protein-protein interactions (PPI) of a model mAb molecule under near-neutral and acidic conditions. The study …

Noise In The Ligo Livingston Gravitational Wave Observatory Due To Trains, J. Glanzer, S. Soni, J. Spoon, A. Effler, G. González

Faculty Publications

Environmental seismic disturbances limit the sensitivity of LIGO gravitational wave detectors. Trains near the LIGO Livingston detector produce low frequency (0.5- 10 H z ) ground noise that couples into the gravitational wave sensitive frequency band (10- 100 H z ) through light reflected in mirrors and other surfaces. We investigate the effect of trains during the Advanced LIGO third observing run, and propose a method to search for narrow band seismic frequencies responsible for contributing to increases in scattered light. Through the use of the linear regression tool Lasso (least absolute shrinkage and selection operator) and glitch correlations, we …

Backward Stochastic Differential Equations In A Semi-Markov Chain Model, Robert J. Elliott, Zhe Yang

Journal of Stochastic Analysis

No abstract provided.

International Pediatric Covid-19 Severity Over The Course Of The Pandemic, Yanshan Zhu, Flávia Jacqueline Almeida, J. Kenneth Baillie, Asha C. Bowen, Philip N. Britton, Martin Eduardo Brizuela, Danilo Buonsenso, David Burgner, Keng Yih Chew, Kulkanya Chokephaibulkit, Cheryl Cohen, Stephania A. Cormier, Nigel Crawford, Nigel Curtis, Camila G.A. Farias, Charles F. Gilks, Anne Von Gottberg, Diana Hamer, Daniel Jarovsky, Waasila Jassat, Ana Rita Jesus, Lisa S. Kemp, Benjawan Khumcha, Georgina Mccallum, Jessica E. Miller, Rosa Morello, Alasdair P.S. Munro, Peter J.M. Openshaw, Srivatsan Padmanabhan, Wanatpreeya Phongsamart, Gary Reubenson, Nicole Ritz, Fernanda Rodrigues, Supattra Rungmaitree

Division of Basic Science Faculty Publications

Importance: Multiple SARS-CoV-2 variants have emerged over the COVID-19 pandemic. The implications for COVID-19 severity in children worldwide are unclear. Objective: To determine whether the dominant circulating SARS-CoV-2 variants of concern (VOCs) were associated with differences in COVID-19 severity among hospitalized children. Design, Setting, and Participants: Clinical data from hospitalized children and adolescents (younger than 18 years) who were SARS-CoV-2 positive were obtained from 9 countries (Australia, Brazil, Italy, Portugal, South Africa, Switzerland, Thailand, UK, and the US) during 3 different time frames. Time frames 1 (T1), 2 (T2), and 3 (T3) were defined to represent periods of dominance by …

An Investigation Into The Characteristics Of Reactive Silicon Pools Of Coastal Marine Sediments, Rebecca A. Pickering, Xiangli L. Wang, Katharine R. Hendry, Kanchan Maiti, Jeffrey W. Krause

Faculty Publications

Many studies use traditional alkaline leach digestions to quantify biogenic silica (bSiO2) in sediments. Studies from river-plume systems demonstrate this methodology precludes information on other operational Si reactive pools, missing potentially valuable information on early diagenetic products. We build on previous studies by broadly examining the reactive Si pools in Mississippi River plume-influenced coastal sediments. The magnitude of Si released among operational pools across the region revealed large spatial variations in the conservation of detrital materials. Contrary to other analyses using different approaches, we suggest the availability of detrital sourced components (i.e. Al, Fe and Mn) may be a factor …

Regional Variation In The Trophic Ecology Of Wahoo (Acanthocybium Solandri) In The Western Atlantic Ocean, Brendan Gough, Alexandra Prouse, Michael A. Dance, R. J.David Wells, Jay R. Rooker

Faculty Publications

Intrinsic tracers, such as stable isotopes of carbon and nitrogen, are common dietary markers that accumulate in the muscle tissue of consumers and can be used to determine the dietary sources and trophic positions of consumers. The aim of this study was to assess regional variation in the trophic ecology of wahoo (Acanthocybium solandri) using bulk stable isotopes. Muscle biopsies of wahoo were collected from four regions in the western Atlantic Ocean: the eastern Gulf of Mexico, western Gulf of Mexico, Northwest Atlantic Ocean, and Caribbean Sea. Muscle tissue δ¹³C and δ¹⁵N values for wahoo ranged …

Journey Of A Thousand Miles: From Manpo-Kei' To The First Steps-Based Physical Activity Recommendations, Emmanuel Stamatakis, Matthew Ahmadi, Marie H. Murphy, Timothy James Chico, Karen Milton, Borja Del Pozo Cruz, Peter T. Katzmarzyk, I. Min Lee, Jason Gill

Population and Public Health Science Faculty Publications

No abstract provided.

Second International Consensus Report On Gaps And Opportunities For The Clinical Translation Of Precision Diabetes Medicine, Deirdre K. Tobias, Jordi Merino, Abrar Ahmad, Catherine Aiken, Jamie L. Benham, Dhanasekaran Bodhini, Amy L. Clark, Kevin Colclough, Rosa Corcoy, Sara J. Cromer, Daisy Duan, Jamie L. Felton, Ellen C. Francis, Pieter Gillard, Véronique Gingras, Romy Gaillard, Eram Haider, Alice Hughes, Jennifer M. Ikle, Laura M. Jacobsen, Anna R. Kahkoska, Jarno L.T. Kettunen, Raymond J. Kreienkamp, Lee Ling Lim, Jonna M.E. Männistö, Robert Massey, Niamh Maire Mclennan, Rachel G. Miller, Mario Luca Morieri, Jasper Most, Rochelle N. Naylor, Bige Ozkan, Kashyap Amratlal Patel, Scott J. Pilla

Clinical Research Faculty Publications

Precision medicine is part of the logical evolution of contemporary evidence-based medicine that seeks to reduce errors and optimize outcomes when making medical decisions and health recommendations. Diabetes affects hundreds of millions of people worldwide, many of whom will develop life-threatening complications and die prematurely. Precision medicine can potentially address this enormous problem by accounting for heterogeneity in the etiology, clinical presentation and pathogenesis of common forms of diabetes and risks of complications. This second international consensus report on precision diabetes medicine summarizes the findings from a systematic evidence review across the key pillars of precision medicine (prevention, diagnosis, treatment, …

White Adipose Tissue Heterogeneity In The Single-Cell Era: From Mice And Humans To Cattle, Hunter Ford, Qianglin Liu, Xing Fu, Clarissa Strieder-Barboza

Faculty Publications

Adipose tissue is a major modulator of metabolic function by regulating energy storage and by acting as an endocrine organ through the secretion of adipokines. With the advantage of next-generation sequencing-based single-cell technologies, adipose tissue has been studied at single-cell resolution, thus providing unbiased insight into its molecular composition. Recent single-cell RNA sequencing studies in human and mouse models have dissected the transcriptional cellular heterogeneity of subcutaneous (SAT), visceral (VAT), and intramuscular (IMAT) white adipose tissue depots and revealed unique populations of adipose tissue progenitor cells, mature adipocytes, immune cell, vascular cells, and mesothelial cells that play direct roles on …