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The Influence Of Stage Of Ripeness On Consumer Perceptions Regarding Selected Aspects Of Non-Astringent Asian Persimmons (Diospyros Kaki Thunb), Robert A. Mirabello Jr May 2024

The Influence Of Stage Of Ripeness On Consumer Perceptions Regarding Selected Aspects Of Non-Astringent Asian Persimmons (Diospyros Kaki Thunb), Robert A. Mirabello Jr

LSU Doctoral Dissertations

Asian Persimmon (Diospyros kaki Thunb.) is an important fruit crop in Asia and in recent decades has experienced expanding production around the world. Non-astringent cultivars are highly desirable in world markets. In the United States the Asian Persimmon is lesser known and consumed although it can be successfully grown in California and the Southeastern United States.This novel study examined the physical/chemical properties of the non-astringent Asian Persimmon ‘Jiro’ grown in Southern Louisiana at three distinct stages of ripeness described as Green (mid-September harvest), Light Orange (mid-October harvest) and Dark Orange (mid-November harvest). Data collected included color, weight, size, soluble …


Pregnant Black Bodies In Peril: A Multi-Method Analysis Of Obstetric Outcomes And Gestational Experiences, Courtney E. Williams May 2024

Pregnant Black Bodies In Peril: A Multi-Method Analysis Of Obstetric Outcomes And Gestational Experiences, Courtney E. Williams

LSU Doctoral Dissertations

My multi-method three-paper dissertation provides a better understanding of the relationship between maternal racial identity, obstetric outcomes, and gestational experiences. Using birth certificate data from the 2016 U.S. National Vital Statistics System and binary logistic regression models, in the first paper I explore heterogeneity in severe maternal morbidity (SMM) by maternal race, maternal education, and maternal age. To complement the first paper, in the second paper I allow 35 Black and White women/birthing people to describe pregnancy, birth, and early motherhood in their own words. I situate the Covid-19 pandemic as a unique cultural backdrop in this qualitative paper to …


Extreme Climate Events And Agricultural Commodity Markets, Mohammad Abir Chowdhury Shovon May 2024

Extreme Climate Events And Agricultural Commodity Markets, Mohammad Abir Chowdhury Shovon

LSU Master's Theses

This article investigates the impact of extreme climate events on U.S. agricultural commodity markets, specifically focusing on corn and soybeans. Using event study methods and a comprehensive dataset of 254 extreme climate events for corn as well as 250 extreme climate events for soybeans in top ten corn & soybeans producing states of the USA between 1995 and 2023, we examine how storms, floods, extreme temperatures, and droughts affect the abnormal returns of these commodities. Our findings indicate that 22.04% of climate events significantly impact corn returns and 21.20% of climate events have significant impact on soybeans returns. Notably, extreme …


Synthesis And Regioselective Functionalization Of Tetrafluorobenzo-[Α]-Fused Bopypy Dyes, Sebastian O. Oloo, Guanyu Zhang, Petia Bobadova-Parvanova, Seleen Al Horani, Masa Al Horani, Frank R. Fronczek, Kevin M. Smith, Maria Da Graça H. Vicente May 2024

Synthesis And Regioselective Functionalization Of Tetrafluorobenzo-[Α]-Fused Bopypy Dyes, Sebastian O. Oloo, Guanyu Zhang, Petia Bobadova-Parvanova, Seleen Al Horani, Masa Al Horani, Frank R. Fronczek, Kevin M. Smith, Maria Da Graça H. Vicente

Faculty Publications

The synthesis of a new bis-BF2 tetrafluorobenzo-[α]-fused BOPYPY dye from 4,5,6,7-tetrafluoroisoindole and 2-hydrazinopyrazine is reported. The regioselectivity of nucleophilic substitution reactions at the periphery of the tetrafluorinated BOPYPY and its α-bromo derivative were investigated using N-, O-, S-, and C-based nucleophiles. Among the aromatic fluorine atoms, the F2 atom is consistently regioselectively substituted, except when the α-position contains a thiophenol group; in this case, F4 is substituted instead due to stabilizing π-π-stacking between the two aromatic groups. The α-bromo BOPYPY derivative also reacts under Stille cross-coupling reaction conditions to produce the corresponding α-substituted product. The spectroscopic properties of …


Identifying Self-Efficacy Factors Of Agriscience Teachers When Working With Supervised Agricultural Experiences For Students With Disabilities, Saralyn L. Smith May 2024

Identifying Self-Efficacy Factors Of Agriscience Teachers When Working With Supervised Agricultural Experiences For Students With Disabilities, Saralyn L. Smith

LSU Master's Theses

The number of students receiving disability services annually in the U.S. has increased in the last decade. Even with this growing population of students with disabilities, research continues to show a lack of confidence of School Based Agricultural Education (SBAE) teachers in their ability and skills to include these students. The purpose of this qualitative study was to describe the factors that influence how SBAE teachers support students with disabilities in Supervised Agricultural Experience Programs and identify perceived obstacles SBAE teachers have regarding working with students with disabilities. Semi-structed interviews were conducted with twelve SBAE teachers to understand their lived …


Controlling Phase Transitions In Mnnige Using Thermal Quenching And Hydrostatic Pressure, Jing Han Chen, Tej Poudel Chhetri, Anthony T. Grant, Xiaojian Bai, Qiang Zhang, Chung Kai Chang, David P. Young, Igor Dubenko, Saikat Talapatra, Naushad Ali, Shane Stadler May 2024

Controlling Phase Transitions In Mnnige Using Thermal Quenching And Hydrostatic Pressure, Jing Han Chen, Tej Poudel Chhetri, Anthony T. Grant, Xiaojian Bai, Qiang Zhang, Chung Kai Chang, David P. Young, Igor Dubenko, Saikat Talapatra, Naushad Ali, Shane Stadler

Faculty Publications

The phase transitions in MnNiGe compounds were explored by manipulating the heat treatment conditions and through hydrostatic pressure application. As the quenching temperature increased, both the first-order martensitic structural transition temperatures and magnetic transition temperatures decreased relative to those in the slowly-cooled samples. When the samples were quenched from 1200 °C, the first-order martensitic structural transition temperature lowered by more than 200 K. The structural transitions also shifted to lower temperature with the application of hydrostatic pressure during measurement. Temperature-dependent x-ray diffraction results reveal that the changes of the cell parameters resulting from the structural transitions are nearly identical for …


Learning Proximal Operators With Gaussian Process And Adaptive Quantization In Distributed Optimization, Aldo Duarte Vera Tudela May 2024

Learning Proximal Operators With Gaussian Process And Adaptive Quantization In Distributed Optimization, Aldo Duarte Vera Tudela

LSU Doctoral Dissertations

In networks consisting of agents communicating with a central coordinator and working together to solve a global optimization problem in a distributed manner, the agents are often required to solve private proximal minimization subproblems. Such a setting often requires a further decomposition method to solve the global distributed problem, resulting in extensive communication overhead. In networks where communication is expensive, it is crucial to reduce the communication overhead of the distributed optimization scheme. Integrating Gaussian processes (GP) as a learning component to the Alternating Direction Method of Multipliers (ADMM) has proven effective in learning each agent's local proximal operator to …


Optics Design And Fabrication For A Lung Interferometry-Radiography System, Rachael Lyn Blair May 2024

Optics Design And Fabrication For A Lung Interferometry-Radiography System, Rachael Lyn Blair

LSU Master's Theses

Purpose: High prevalence of lung diseases leads to many people worldwide needing spirometry and imaging testing. The typical imaging done uses chest radiography and/or low-dose CT. Lung tissue is difficult to visualize, making them substandard for monitoring lung disease progression. An improvement on these systems is x-ray interferometry which produces additional images that provide better visualization of changes in the lung tissue. The set-up of x-ray interferometry builds upon other imaging systems in that it includes diffraction gratings.

Materials: This thesis focused on implementing the fabrication processes to create diffraction gratings for a lung imager prototype that is currently under …


Decay Spectroscopy Of 134sb Using X-Array And Saturn, Graeme E. Morgan May 2024

Decay Spectroscopy Of 134sb Using X-Array And Saturn, Graeme E. Morgan

LSU Doctoral Dissertations

The ground-state decay of 134Sb is reported by the current evaluated nuclear data to be dominated by a 0-→0+ first-forbidden Gamow-Teller transition to the ground state of 134Te. In 2013, a recoil-ion time-of-flight (RI-TOF) spectroscopy measurement of 134Sb with the Beta-decay Paul Trap (BPT) indicated that the ground-state feeding of 134Te is weaker than reported. Simulation work of 134Sb ground-state decays replicated the RI-TOF results with the addition of a theorised 5-MeV state that was fed with ~17% of the total β-decay strength. To search for higher energy states and transitions that …


Struggling To Be Positive Problem Solvers – A Study On The Relationship Of Elementary Mathematical Self-Concept, Gender, Learner Identification, And Productive Struggle Trajectories On Constructed Response Questions When Being Taught With A Standardized Curriculum, Kali D. Rogers May 2024

Struggling To Be Positive Problem Solvers – A Study On The Relationship Of Elementary Mathematical Self-Concept, Gender, Learner Identification, And Productive Struggle Trajectories On Constructed Response Questions When Being Taught With A Standardized Curriculum, Kali D. Rogers

LSU Doctoral Dissertations

Mathematical word problems are some of the most difficult problems for students to solve due to their complexity and relationship to real-world situations (Şahin et al., 2014; Verschaffel et al., 2020). With math being known for right-or-wrong answers, these open-ended questions cause much confusion and frustration, specifically for students of various subgroups. In the last several decades, educational teaching expectations have shifted from engaging, self-created learning to robotic and redundant curriculum expectations that induce a ‘teaching to the test’ environment (Shafiyeva, 2021). Mathematics is the powerhouse of where students can experience and succeed with productive struggle learning that teaches the …


Coordination Numbers And Grain Texture From Micro-Xray Tomography Of Angular Unconsolidated Sediments: Velocity Prediction Using Hertz-Mindlin Model., Kwabena Poku-Agyemang May 2024

Coordination Numbers And Grain Texture From Micro-Xray Tomography Of Angular Unconsolidated Sediments: Velocity Prediction Using Hertz-Mindlin Model., Kwabena Poku-Agyemang

LSU Master's Theses

Elastic properties of unconsolidated sediments depend on parameters such as porosity, grain texture (i.e., grain shape and sizes), sorting and coordination number. Coordination is the average number of grains each grain has with touching grains, is a critical parameter in rock physics models for estimating elastic moduli of materials. While previous works have focused on the influence of porosity and sorting on coordination numbers within well-rounded grains, natural sediments have a wide range of grain shapes and sizes, and it remains unclear how these parameters influence coordination numbers within angular unconsolidated sediments.

We investigate the impact of porosity, sorting and …


Educator Perceptions Of Working With Dreambox Learning, H. Colleen Sinclair, Nathaniel Armour, Judith L. F. Rhodes, Alyssa Spears May 2024

Educator Perceptions Of Working With Dreambox Learning, H. Colleen Sinclair, Nathaniel Armour, Judith L. F. Rhodes, Alyssa Spears

Reports

As part of a research-practitioner partnership with East Baton Rouge Parish School System (EBRPSS), LSU Social Research & Evaluation Center, and DreamBox Learning, we wanted to evaluate educator perceptions of the implementation of a digital learning platform into K-12 math classes. Our aim was to find ways to optimize both the program and the implementation to best enable educators to facilitate student success in math, especially for students who may be struggling. To do this, our initial step was to go to the educators and simply ask them about their experiences. This report outlines the procedures and the detailed examples …


Vibrato Rate And Extent In The Baritone Voice Through The Twentieth And Early Twenty-First Century, Scott Purcell May 2024

Vibrato Rate And Extent In The Baritone Voice Through The Twentieth And Early Twenty-First Century, Scott Purcell

LSU Doctoral Dissertations

Observations of vibrato rate and extent through the twentieth and early twenty-first century point to an overall decrease in rate and increase in extent. This descriptive analysis studied fifty-five randomly selected recordings of professional operatic baritones, five from each decade from 1910 to 2021, and analyzed their vibrato rate and extent with VoceVista Video Pro. Results showed a consistent decrease in mean vibrato rate from 1910 to 1960, with small increases and decreases from 1960-2021. Vibrato extent was less consistent, but still increased from 1910-2021. The mean vibrato rate was 5.84 Herz (Hz), with a coefficient of variation (CV) of …


An Analysis Of The Musical Gestures In Osvaldo Golijov’S The Dreams And Prayers Of Isaac The Blind And Their Relationship To The Kabbalah Sefirot, Jeremy Gdaniec May 2024

An Analysis Of The Musical Gestures In Osvaldo Golijov’S The Dreams And Prayers Of Isaac The Blind And Their Relationship To The Kabbalah Sefirot, Jeremy Gdaniec

LSU Doctoral Dissertations

Osvlado Golijov’s The Dreams and Prayers of Isaac the Blind, scored for klezmer clarinet and string quartet, remains one of his most influential works since its premier in 1994. Inspiration for the work came from the writings of Rabbi Isaac the Blind, a prominent 13th century figurehead in the branch of Jewish mysticism known as Kabbalah. In Kabbalah, symbols known as the sefirot are emanations of creation and the key to unlocking the divine secrets of the God-head. The analysis presented in this document combines musical gesture theory with Kabbalistic concepts for new perspectives on Golijov’s …


Examining The Use Of Vr As A Study Aid For University Students With Adhd, Isabelle Cuber, Juliana G. Goncalves De Souza, Irene Jacobs, Caroline Lowman, David Shepherd, Thomas Fritz, Joshua M. Langberg May 2024

Examining The Use Of Vr As A Study Aid For University Students With Adhd, Isabelle Cuber, Juliana G. Goncalves De Souza, Irene Jacobs, Caroline Lowman, David Shepherd, Thomas Fritz, Joshua M. Langberg

Faculty Publications

Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental condition characterized by patterns of inattention and impulsivity, which lead to difficulties maintaining concentration and motivation while completing academic tasks. University settings, characterized by a high student-to-staf ratio, make treatments relying on human monitoring challenging. One potential replacement is Virtual Reality (VR) technology, which has shown potential to enhance learning outcomes and promote fow experience. In this study, we investigate the usage of VR with 27 university students with ADHD in an efort to improve their performance in completing homework, including an exploration of automated feedback via a technology probe. Quantitative results show significant …


Examining The Authenticity Of The 'Ether Model' In Certain O-Glycosylation Reactions, Varad Vinayak Agarkar May 2024

Examining The Authenticity Of The 'Ether Model' In Certain O-Glycosylation Reactions, Varad Vinayak Agarkar

LSU Doctoral Dissertations

Acinetobacter baumannii is a gram-negative bacterium species that is responsible for nosocomial infections. It has shown antibiotic resistance and has been designated an urgent threat by the CDC. In Chapter 1, I highlight my efforts in the synthesis of a Kdo building block in the journey towards the construction of an A. baumannii lipooligosaccharide (LOS) core pentasaccharide- a potential candidate for glycoconjugate vaccine against A. baumannii infection. I talk about various optimizations and improvements in the Kdo monosaccharide synthesis and the mechanistic insights I provided about a critical transformation in the synthetic sequence.

Chemical O-glycosylation is a significant research …


Multiphoton Quantum Sensing, Fatemeh Mostafavikhatam May 2024

Multiphoton Quantum Sensing, Fatemeh Mostafavikhatam

LSU Doctoral Dissertations

While the fundamental principles of light-matter interaction are well-understood and drive countless technologies, the world of multiphoton processes remains a fascinating puzzle, holding the potential to drastically alter our understanding of how light interacts with matter at its most basic level [1–4]. This rich interplay of light and matter unveils novel phenomena that can be harnessed for sensing with exceptional precision, as exemplified by multiphoton quantum sensing. This thesis delves into the applications of multiphoton quantum protocols, particularly in imaging, communication, and plasmonic sensing, to surpass classical limitations and achieve enhanced sensitivity. We explore the potential of multiphoton quantum processes, …


Temporal Dynamics Of The Multi-Omic Response To Endurance Exercise Training, David Amar, Nicole R. Gay, Pierre M. Jean-Beltran, Dam Bae, Surendra Dasari, Courtney Dennis, Charles R. Evans, David A. Gaul, Olga Ilkayeva, Anna A. Ivanova, Maureen T. Kachman, Hasmik Keshishian, Ian R. Lanza, Ana C. Lira, Michael J. Muehlbauer, Venugopalan D. Nair, Paul D. Piehowski, Jessica L. Rooney, Kevin S. Smith, Cynthia L. Stowe, Bingqing Zhao, Natalie M. Clark, David Jimenez-Morales, Malene E. Lindholm, Gina M. Many, James A. Sanford, Gregory R. Smith, Nikolai G. Vetr, Tiantian Zhang, Jose J. Almagro Armenteros, Julian Avila-Pacheco, Nasim Bararpour, Yongchao Ge, Zhenxin Hou May 2024

Temporal Dynamics Of The Multi-Omic Response To Endurance Exercise Training, David Amar, Nicole R. Gay, Pierre M. Jean-Beltran, Dam Bae, Surendra Dasari, Courtney Dennis, Charles R. Evans, David A. Gaul, Olga Ilkayeva, Anna A. Ivanova, Maureen T. Kachman, Hasmik Keshishian, Ian R. Lanza, Ana C. Lira, Michael J. Muehlbauer, Venugopalan D. Nair, Paul D. Piehowski, Jessica L. Rooney, Kevin S. Smith, Cynthia L. Stowe, Bingqing Zhao, Natalie M. Clark, David Jimenez-Morales, Malene E. Lindholm, Gina M. Many, James A. Sanford, Gregory R. Smith, Nikolai G. Vetr, Tiantian Zhang, Jose J. Almagro Armenteros, Julian Avila-Pacheco, Nasim Bararpour, Yongchao Ge, Zhenxin Hou

Clinical Research Faculty Publications

Regular exercise promotes whole-body health and prevents disease, but the underlying molecular mechanisms are incompletely understood1–3. Here, the Molecular Transducers of Physical Activity Consortium4 profiled the temporal transcriptome, proteome, metabolome, lipidome, phosphoproteome, acetylproteome, ubiquitylproteome, epigenome and immunome in whole blood, plasma and 18 solid tissues in male and female Rattus norvegicus over eight weeks of endurance exercise training. The resulting data compendium encompasses 9,466 assays across 19 tissues, 25 molecular platforms and 4 training time points. Thousands of shared and tissue-specific molecular alterations were identified, with sex differences found in multiple tissues. Temporal multi-omic and multi-tissue analyses revealed expansive biological …


Modes Of Weather System-Induced Flows Through An Arctic Lagoon, Chunyan Li, Wei Huang, Changsheng Chen, Kevin M. Boswell, Renhao Wu May 2024

Modes Of Weather System-Induced Flows Through An Arctic Lagoon, Chunyan Li, Wei Huang, Changsheng Chen, Kevin M. Boswell, Renhao Wu

Faculty Publications

With the increasing warming of the Arctic, the summertime ice-free period in the coastal Arctic becomes longer and the water exchange between arctic lagoons and coastal Beaufort Sea becomes more important for land–ocean interaction. This study examined the dynamics of water exchange between the arctic lagoons and the Arctic Ocean under the influence of weather systems (the transient arctic cyclones and hovering Beaufort High pressure system). We implemented rare observations, numerical modeling with the Finite Volume Community Ocean Model (FVCOM), and a forcing-response Empirical Orthogonal Function (fr-EOF) analysis to determine the weather-driven flow patterns and characteristics in the micro-tidal arctic …


Restricting Bioenergetic Efficiency Enhances Longevity And Mitochondrial Redox Capacity In Drosophila Melanogaster, Analisa L. Taylor, Olga Dubuisson, Pritika Pandey, Elizabeth R.M. Zunica, Bolormaa Vandanmagsar, Wagner S. Dantas, Alyssa Johnson, Christopher L. Axelrod, John P. Kirwan May 2024

Restricting Bioenergetic Efficiency Enhances Longevity And Mitochondrial Redox Capacity In Drosophila Melanogaster, Analisa L. Taylor, Olga Dubuisson, Pritika Pandey, Elizabeth R.M. Zunica, Bolormaa Vandanmagsar, Wagner S. Dantas, Alyssa Johnson, Christopher L. Axelrod, John P. Kirwan

Division of Basic Science Faculty Publications

Mitochondria are essential for survival and as such, impairments in organelle homeostasis significantly accelerate age-related morbidity and mortality. Here, we determined the contribution of bioenergetic efficiency to life span and health span in Drosophila melanogaster utilizing the mitochondrial uncoupler BAM15. Life span was determined in flies fed a normal diet (ND) or high fat diet (HFD) supplemented with vehicle or BAM15. Locomotor function was determined by negative geotaxis assay in middle-aged flies fed vehicle or BAM15 under ND or HFD conditions. Redox capacity (high-resolution respirometry/fluorometry), citrate synthase (enzyme activity), mtDNA content (qPCR), gene expression (qPCR), and protein expression (western blot) …


Detection Of Ochyromera Ligustri (Coleoptera: Curculionidae: Curculioninae) In Ligustrum Spp. (Oleaceae) Using Newly Developed Pcr Primers, Ilgoo Kang, Amy Roda, Brandi Misiaszek, Tanner Sparks, Rodrigo Diaz May 2024

Detection Of Ochyromera Ligustri (Coleoptera: Curculionidae: Curculioninae) In Ligustrum Spp. (Oleaceae) Using Newly Developed Pcr Primers, Ilgoo Kang, Amy Roda, Brandi Misiaszek, Tanner Sparks, Rodrigo Diaz

Faculty Publications

Ligustrum spp. (Oleaceae) have become invasive species in the US and negatively affect native plant diversity and richness in forests. Ochyromera ligustri (Coleoptera: Curculionidae) is considered a potential biological control agent in the US because adults feed on the foliage and larvae are seed-feeders of Ligustrum spp. To discover the relationships between O. ligustri and Ligustrum spp., fruit dissections or rearing and field observations are required. In the current research project, novel PCR primers were developed to rapidly detect the DNA of O. ligustri in molecular analyses without rearing and observation. The developed PCR primers worked even with 0.01 ng …


Breaking The Spatial Justice Emergency Cycle: The Role Of Foresight Planning, Fabio Capra-Ribeiro May 2024

Breaking The Spatial Justice Emergency Cycle: The Role Of Foresight Planning, Fabio Capra-Ribeiro

Faculty Publications

This paper examines the critical need to integrate prospective planning into territorial development processes for achieving spatial justice and sustainable urban futures. It highlights the limitations of a reactive approach to urban governance, particularly prevalent in Latin America, where weak institutions and unstable political systems often hinder long-term perspectives. The research emphasizes the importance of strategic foresight as a complementary tool to traditional planning practices. Territorial foresight facilitates the exploration of complex future scenarios, fostering collaborative learning and a shared vision among stakeholders. The study proposes a shift towards a proactive, foresight-driven approach that can help break the vicious cycle …


Spatial Justice: Deductions, Demonstrations, And Derivations, Fabio Capra-Ribeiro May 2024

Spatial Justice: Deductions, Demonstrations, And Derivations, Fabio Capra-Ribeiro

Faculty Publications

No abstract provided.


Mapping And Omics Integration: Towards Precise Rice Disease Resistance Breeding, John Christian Ontoy, Jong Hyun Ham May 2024

Mapping And Omics Integration: Towards Precise Rice Disease Resistance Breeding, John Christian Ontoy, Jong Hyun Ham

Faculty Publications

Rice (Oryza sativa), as a staple crop feeding a significant portion of the global population, particularly in Asian countries, faces constant threats from various diseases jeopardizing global food security. A precise understanding of disease resistance mechanisms is crucial for developing resilient rice varieties. Traditional genetic mapping methods, such as QTL mapping, provide valuable insights into the genetic basis of diseases. However, the complex nature of rice diseases demands a holistic approach to gain an accurate knowledge of it. Omics technologies, including genomics, transcriptomics, proteomics, and metabolomics, enable a comprehensive analysis of biological molecules, uncovering intricate molecular interactions within the rice …


Exploring Pathways Toward Open-Hardware Ecosystems To Safeguard Genetic Resources For Biomedical Research Communities Using Aquatic Model Species, Yue Liu, Jack C. Koch, Lucía Arregui, Allyssa Oune, Sarah Bodenstein, Maria T. Gutierrez-Wing, Terrence R. Tiersch May 2024

Exploring Pathways Toward Open-Hardware Ecosystems To Safeguard Genetic Resources For Biomedical Research Communities Using Aquatic Model Species, Yue Liu, Jack C. Koch, Lucía Arregui, Allyssa Oune, Sarah Bodenstein, Maria T. Gutierrez-Wing, Terrence R. Tiersch

Faculty Publications

Development of reliable germplasm repositories is critical for preservation of genetic resources of aquatic species, which are widely utilized to support biomedical innovation by providing a foundational source for naturally occurring variation and development of new variants through genetic manipulations. A significant barrier in repository development is the lack of cryopreservation capability and reproducibility across the research community, posing great risks of losing advances developed from billions of dollars of research investment. The emergence of open scientific hardware has fueled a new movement across biomedical research communities. With the increasing accessibility of consumer-level fabrication technologies, such as three-dimensional printers, open …


Sexual Orientation-Based Microaggressions And Cannabis Use Outcomes Among Sexual Minority Individuals: The Impact Of Negative Affect And Coping-Motivated Cannabis Use, Evan M. Threeton, Paige E. Morris, Julia D. Buckner May 2024

Sexual Orientation-Based Microaggressions And Cannabis Use Outcomes Among Sexual Minority Individuals: The Impact Of Negative Affect And Coping-Motivated Cannabis Use, Evan M. Threeton, Paige E. Morris, Julia D. Buckner

Faculty Publications

Introduction: Sexual minority individuals report significantly more cannabis use and problems than their heterosexual peers, possibly due to their frequent experiences with sexual orientation-based microaggressions. As a result, sexual minority individuals may turn to cannabis use to cope with the negative affect associated with these experiences. No known studies have tested this hypothesis; therefore, the current study tested if sexual orientation microaggressions are positively associated with negative affect (anxiety and depression), cannabis coping motives, and cannabis-related outcomes (frequency, problems); if coping motives are positively associated with cannabis-related outcomes; and if negative affect and cannabis use to cope with negative affect …


Differential Risk: Gender And Racial Differences In The Relationship Between Trauma, Discrimination, And Schizotypy, Mahogany A. Monette, Madisen T. Russell, Danielle B. Abel, Jarrett T. Lewis, Jessica L. Mickens, Evan J. Myers, Megan M. Hricovec, David C. Cicero, J. Wolny, William P. Hetrick, Michael D. Masucci, Alex S. Cohen, Christopher J. Burgin, Thomas R. Kwapil, Kyle S. Minor May 2024

Differential Risk: Gender And Racial Differences In The Relationship Between Trauma, Discrimination, And Schizotypy, Mahogany A. Monette, Madisen T. Russell, Danielle B. Abel, Jarrett T. Lewis, Jessica L. Mickens, Evan J. Myers, Megan M. Hricovec, David C. Cicero, J. Wolny, William P. Hetrick, Michael D. Masucci, Alex S. Cohen, Christopher J. Burgin, Thomas R. Kwapil, Kyle S. Minor

Faculty Publications

Traumatic experiences are associated with increased experiences of positive schizotypy. This may be especially important for People of Color, who experience higher rates of trauma and racial discrimination. No study to date has examined how racial disparities in traumatic experiences may impact schizotypy. Furthermore, of the studies that have examined the relationship between trauma and schizotypy, none have examined racial discrimination as a potential moderator. The present study examined if racial discrimination moderates the relationship between trauma and multidimensional (positive, negative, and disorganized) schizotypy. In a sample of 770 college students, we conducted chi-squared analyses, analyses of variance, and stepwise …


Kat8 Beyond Acetylation: A Survey Of Its Epigenetic Regulation, Genetic Variability, And Implications For Human Health, Lindsey Yoo, David Mendoza, Allison J. Richard, Jacqueline M. Stephens May 2024

Kat8 Beyond Acetylation: A Survey Of Its Epigenetic Regulation, Genetic Variability, And Implications For Human Health, Lindsey Yoo, David Mendoza, Allison J. Richard, Jacqueline M. Stephens

Division of Basic Science Faculty Publications

Lysine acetyltransferase 8, also known as KAT8, is an enzyme involved in epigenetic regulation, primarily recognized for its ability to modulate histone acetylation. This review presents an overview of KAT8, emphasizing its biological functions, which impact many cellular processes and range from chromatin remodeling to genetic and epigenetic regulation. In many model systems, KAT8’s acetylation of histone H4 lysine 16 (H4K16) is critical for chromatin structure modification, which influences gene expression, cell proliferation, differentiation, and apoptosis. Furthermore, this review summarizes the observed genetic variability within the KAT8 gene, underscoring the implications of various single nucleotide polymorphisms (SNPs) that affect its …


Transitioning From A Research Protocol To A Scalable Applied Pathway For Xenopus Laevis Sperm Cryopreservation At A National Stock Center: The Effect Of Cryoprotectants, Lucía Arregui, Jack C. Koch, Terrence R. Tiersch May 2024

Transitioning From A Research Protocol To A Scalable Applied Pathway For Xenopus Laevis Sperm Cryopreservation At A National Stock Center: The Effect Of Cryoprotectants, Lucía Arregui, Jack C. Koch, Terrence R. Tiersch

Faculty Publications

Sperm cryopreservation is a critical tool for safeguarding and managing valuable genetic resources. Protocols for cryopreservation of Xenopus laevis sperm were available but lacking sperm quality evaluation and scalability and the outcomes were inconsistent. The goal of this study was to begin developing a center-level cryopreservation pathway for this species by integrating French straws as containers that would facilitate germplasm repository development. The objectives were to analyze the effect of: (1) three sperm concentrations (33, 50, and 100 × 106 sperm/mL) on post-thaw fertilization, (2) three final concentrations (2.5%, 5%, and 10%) of dimethyl sulfoxide, methanol, and dimethylformamide (DMFA) on …


Energy Compensation For Crop Growth Under Plastic Mulching: Theories, Models, And Limitations, Dianyuan Ding, Ting Li, Lihong Wu, Xi Zhang, Ying Zhao, Hao Feng, Chao Zhang, Ole Wendroth May 2024

Energy Compensation For Crop Growth Under Plastic Mulching: Theories, Models, And Limitations, Dianyuan Ding, Ting Li, Lihong Wu, Xi Zhang, Ying Zhao, Hao Feng, Chao Zhang, Ole Wendroth

Faculty Publications

Plastic film mulching (PM) is a useful agronomic means to adapt to the environmental conditions of dryland agriculture and improve crop production. To improve the theoretical framework of PM technology, this study focuses on the interaction between the soil temperature change caused by PM and crop growth. The definition, action mechanism, and simulation of the compensatory effect of PM on growing degree days are introduced to reveal the effect of soil temperature under PM on crop development and growth. Our summary shows that the strength of the warming effect changes with the growth and development of crops, strengthening during the …